Reagent conveying device and blood analyzer

Abstract

The invention discloses a reagent conveying device and a blood analyzer. The reagent conveying device comprises a reagent assembly, a first pipeline, a constant delivery pump assembly, a second pipeline and a controller. The second pipeline is connected to the joint of the first sub-pipeline and the second sub-pipeline of the first pipeline, and the second sub-pipeline is connected with the liquid using assembly through the metering pump assembly. The controller controls the constant delivery pump assembly to be started, so that the reagent in the reagent assembly is conveyed into the liquid using assembly through the first pipeline. When the bubbles detected on the first sub-pipeline are responded, the controller judges that the reagent of the reagent assembly is insufficient, controls the constant delivery pump assembly to be closed, and conveys the bubbles of the first sub-pipeline into the second pipeline, so that the bubbles are prevented from entering the constant delivery pump assembly through the second sub-pipeline, and the safety of the constant delivery pump assembly is improved; the time for discharging bubbles of the reagent conveying device is shortened, and the reagent conveying efficiency and the detection accuracy of the reagent conveying device are improved.

Description

Technical Field

[0001] The present application relates to the technical field of reagent delivery, and particularly to a reagent delivery device and a hematology analyzer. Background Art

[0002] In a hematology analyzer, when the remaining amount of the reagent in the reagent bottle is insufficient and the reagent is still aspirated from the reagent bottle, a large number of bubbles will enter the pipeline. The bubbles are difficult to handle and easily enter the devices connected to the pipeline, affecting the performance of the devices in the hematology analyzer. Therefore, after the bubbles enter the devices and the pipeline, they need to be discharged in time to avoid affecting the detection accuracy. After the bubbles enter different instrument components, the difficulty of discharging the bubbles varies.

[0003] Among them, due to the special structure of the metering pump, the gas and the liquid are separated, and only a fixed amount of liquid can be pumped out, and it is impossible to discharge all the bubbles at one time. Therefore, the bubbles in the metering pump are extremely difficult to handle. Currently, the common technical means is to strengthen the measures for discharging the bubbles in the metering pump after the bubbles enter the metering pump. These means cannot effectively avoid the influence of the bubbles in the metering pump, and often require a large amount of reagent to discharge the bubbles in the metering pump. Summary of the Invention

[0004] The present application provides a reagent delivery device to solve the above technical problems. The reagent delivery device includes:

[0005] a reagent assembly for storing reagents;

[0006] a first pipeline, one end of the first pipeline is connected to the reagent assembly;

[0007] a metering pump assembly, the other end of the first pipeline is connected to a liquid-using assembly through the metering pump assembly;

[0008] a second pipeline, the first end of the second pipeline is connected to the first pipeline;

[0009] a controller, connected to the metering pump assembly, and the controller is configured to:

[0010] control the metering pump assembly to start, and deliver the reagent of the reagent assembly to the liquid-using assembly through the first pipeline;

[0011] in response to detecting bubbles in the first pipeline, determine that the reagent in the reagent assembly is insufficient, control the metering pump assembly to close, deliver the bubbles in the first pipeline to the second pipeline, and replace the reagent assembly to supplement the reagent.

[0012] Among them, the first pipeline includes a first sub-pipeline and a second sub-pipeline; one end of the first sub-pipeline is connected to the reagent assembly, the other end of the first sub-pipeline is connected to one end of the second sub-pipeline, and the other end of the second sub-pipeline is connected to the metering pump assembly;

[0013] The reagent delivery device further includes a reagent detection optocoupler disposed on the first sub-pipeline, and the controller is further connected to the reagent detection optocoupler. Among them, the controller is further configured to:

[0014] Control the reagent detection optocoupler to detect the first sub-pipeline. In response to the reagent detection optocoupler detecting the bubble in the first sub-pipeline, control the metering pump assembly to close so as to transport the bubble to the second pipeline.

[0015] Among them, after the reagent assembly is replaced, the controller is further configured to:

[0016] Control the reagent detection optocoupler to detect the first sub-pipeline. In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the metering pump assembly to open so as to transport the reagent to the liquid using assembly.

[0017] Among them, one end of the second pipeline is connected to the connection point of the first sub-pipeline and the second sub-pipeline. Among them,

[0018] The distance between the reagent detection optocoupler on the first sub-pipeline and the connection point of the first sub-pipeline and the second sub-pipeline is greater than the product of the transport speed of the bubble in the first sub-pipeline and the control time, where the control time is the time from the reagent detection optocoupler detecting the bubble in the first sub-pipeline to the controller controlling the metering pump assembly to close.

[0019] Among them, the metering pump assembly includes a first control valve, a metering pump, a second control valve, a positive pressure source and a negative pressure source;

[0020] Among them, the first end of the first control valve is connected to the first end of the metering pump, the second end of the first control valve is connected to the second sub-pipeline, and the third end of the first control valve is connected to the liquid using assembly;

[0021] The positive pressure source is connected to the first end of the second control valve, the negative pressure source is connected to the second end of the second control valve, and the second end of the metering pump is connected to the third end of the second control valve;

[0022] Among them, the controller is further configured to control the first control valve and the second control valve to open so as to turn on the metering pump assembly and transport the reagent in the second sub-pipeline to the liquid using assembly.

[0023] Wherein, the controller is further configured to:

[0024] Control the first control valve to connect the second sub-pipeline and the metering pump, and control the second control valve to connect the negative pressure source and the metering pump, thereby controlling the start of the negative pressure source, and the metering pump sucks the reagent in the second sub-pipeline into the metering pump;

[0025] Control the first control valve to connect the liquid-using assembly and the metering pump, and control the second control valve to connect the positive pressure source and the metering pump, thereby controlling the start of the positive pressure source, and the metering pump transports the reagent in the metering pump to the liquid-using assembly.

[0026] Wherein, the reagent delivery assembly further includes a power source assembly, which is connected to the second end of the second pipeline, and the controller is also connected to the power source assembly for:

[0027] In response to the reagent detection optocoupler detecting the bubble in the first sub-pipeline, control the first control valve and the second control valve to close, and control the power source assembly to turn on, so as to suck the bubble in the first sub-pipeline into the second pipeline.

[0028] Wherein, the controller is further configured to:

[0029] In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the metering pump assembly to turn on, control the power source assembly to turn off, and the metering pump assembly transports the reagent in the first pipeline to the liquid-using assembly;

[0030] In response to the reagent detection optocoupler detecting the bubble in the first sub-pipeline, control the metering pump assembly to turn off, control the power source assembly to turn on, and the power source assembly sucks the bubble into the second pipeline.

[0031] Wherein, in response to the completion of the replacement of the reagent assembly, the controller is further configured to:

[0032] Control the power source assembly to turn on, so that the reagent in the reagent assembly is transported to the first sub-pipeline.

[0033] In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the power source assembly to turn off after a preset time, and control the metering pump assembly to turn on, so that the metering pump assembly transports the reagent to the liquid-using assembly;

[0034] Wherein, the preset time is greater than or equal to the time for the reagent to reach the connection between the first sub-pipeline and the second sub-pipeline from the reagent detection optocoupler of the first sub-pipeline.

[0035] To solve the above technical problems, the present application also provides a sample analyzer, including the reagent delivery device and the liquid using component as described above. The reagent delivery device is connected to the liquid using component to deliver the reagent to the liquid using component.

[0036] The beneficial effects of the present application: Different from the prior art, the reagent delivery device of the present application includes a reagent component, a first pipeline, a metering pump component, a second pipeline, and a controller. The second pipeline is connected to the connection between the first sub-pipeline and the second sub-pipeline of the first pipeline. The second sub-pipeline is connected to the liquid using component through the metering pump component. The controller controls the metering pump component to start, so as to deliver the reagent in the reagent component to the liquid using component through the first pipeline. And in response to detecting a bubble in the first sub-pipeline, the controller determines that the reagent in the reagent component is insufficient, controls the metering pump component to close, and delivers the bubble in the first sub-pipeline to the second pipeline, avoiding the bubble from entering the metering pump component through the second sub-pipeline, improving the safety of the metering pump component, reducing the time for exhausting bubbles in the reagent delivery device, and improving the efficiency of reagent delivery and the accuracy of detection of the reagent delivery device. Description of the Drawings

[0037] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are only some embodiments of the present application. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0038] Wherein:

[0039] Figure 1 is a schematic structural diagram of an embodiment of the reagent delivery device of the present application.

[0040] Reference numerals in the drawings: Reagent delivery device 1; Reagent component 11; First pipeline 12; First sub-pipeline 121; Second sub-pipeline 122; Metering pump component 13; First control valve 131; Metering pump 132; Second control valve 133; Positive pressure source 134; Negative pressure source 135; Second pipeline 14; Reagent detection optocoupler 15; Power source component 16. Detailed Embodiments

[0041] The following will describe the solutions of the embodiments of the present application in detail with reference to the drawings of the specification.

[0042] In the following description, specific details such as specific system architectures, interfaces, and technologies are presented for the purpose of illustration rather than limitation, in order to provide a thorough understanding of the present application.

[0043] In the present application, the mention of "embodiment" means that the specific features, structures, or characteristics described in connection with the embodiment may be included in at least one embodiment of the present application. The occurrence of this phrase at various positions in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.

[0044] In the present application, the term "and / or" is merely a description of the association relationship of associated objects, indicating that there can be three relationships. For example, A and / or B can represent: A exists alone, A and B exist simultaneously, and B exists alone. In addition, the character " / " in this text generally represents an "or" relationship between the associated objects before and after. Furthermore, "plurality" in this text means two or more than two. In addition, the term "at least one" in this text represents any one of a plurality or any combination of at least two of a plurality. For example, including at least one of A, B, and C can represent including any one or more elements selected from the set composed of A, B, and C. In addition, the terms "first", "second", and "third" in the present application are only for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features.

[0045] Please refer to Figure 1 , Figure 1 is a schematic structural diagram of an embodiment of the reagent delivery device of the present application. The reagent delivery device 1 provided by the embodiment of the present application includes a reagent assembly 11, a first pipeline 12, a metering pump assembly 13, a second pipeline 14, and a controller (not shown in the figure). Among them, the reagent delivery device 1 can be installed inside a sample analyzer or a blood analyzer, etc., to provide reagents for the internal detection devices of the sample analyzer or the blood analyzer, etc.

[0046] Among them, the reagent assembly 11 is used to store reagents; one end of the first pipeline 12 is connected to the reagent assembly 11, and the other end of the first pipeline 12 is connected to the liquid-using assembly through the metering pump assembly 13. Among them, the metering pump assembly 13 is used to quantitatively suck the reagents in the first pipeline 12 to quantitatively provide reagents for the liquid-using assembly. The first end of the second pipeline 14 is connected to the first pipeline 12. The controller is connected to the metering pump assembly 13 and is used to control the opening and closing of the metering pump assembly 13.

[0047] Specifically, the controller can control the metering pump assembly 13 to open, and deliver the reagents in the reagent assembly 11 to the liquid-using assembly through the first pipeline 12. Then, the liquid-using assembly can use the reagents for subsequent operations.

[0048] When the controller detects a bubble on the first pipeline 12, it determines that the reagent in the reagent assembly 11 is insufficient. The controller controls the metering pump assembly 13 to close, so that the bubble or the reagent carrying the bubble is transported into the second pipeline 14, preventing the bubble from entering the metering pump assembly 13 and causing damage to the metering pump assembly 13, reducing the time for venting bubbles in the metering pump assembly 13, and improving the reagent delivery efficiency of the reagent delivery device 1. At the same time, an additional second pipeline 14 is provided to accommodate the bubbles, preventing the situation where, after the metering pump assembly 13 is closed, the bubble enters the first pipeline 12 and then is transported to other devices, thereby improving the safety of the reagent delivery device 1.

[0049] Furthermore, the controller can control the replacement of the reagent assembly 11 to replenish the reagent. In one embodiment, it can be that the controller controls the replacement assembly to automatically replace the reagent assembly 11, or when a bubble is detected on the first pipeline 12, the controller controls the metering pump assembly 13 to close and simultaneously issues an alarm to remind the user to replace the reagent assembly 11. After receiving the alarm, the user replaces the reagent assembly 11 to replenish the reagent in the reagent delivery device 1.

[0050] Optionally, the reagent delivery device 1 further includes a reagent detection optocoupler 15.

[0051] Among them, the first pipeline 12 includes a first sub-pipeline 121 and a second sub-pipeline 122. One end of the first sub-pipeline 121 is connected to the reagent assembly 11, the other end of the first sub-pipeline 121 is connected to one end of the second sub-pipeline 122, and the other end of the second sub-pipeline 122 is connected to the metering pump assembly 13. In one embodiment, as Figure 1 shown, the second pipeline 14 can be connected to the first pipeline 12 through a tee joint. The first end of the tee joint is connected to the first sub-pipeline 121, the second end of the tee joint is connected to the second sub-pipeline 122, and the third end of the tee joint is connected to the second pipeline 14. That is, the first pipeline 12 is divided into the first sub-pipeline 121 and the second sub-pipeline 122 with the tee joint as the boundary, and the second pipeline 14 is connected to the connection point of the first sub-pipeline 121 and the second sub-pipeline 122.

[0052] The reagent detection optocoupler 15 is arranged on the first sub-pipeline 121, and the controller is also connected to the reagent detection optocoupler 15. Among them, when the reagent detection optocoupler 15 detects a bubble on the first sub-pipeline 121, it can quickly upload the information to the controller, and then the controller controls the metering pump assembly 13 to close. And there is a certain time difference from when the reagent detection optocoupler 15 detects a bubble to when the controller controls the metering pump assembly 13 to close. The reagent detection optocoupler 15 is arranged on the first sub-pipeline 121, which can extend the time for the bubble to travel from the reagent detection optocoupler 15 on the first pipeline 12 to the metering pump assembly 13, avoiding the bubble entering the metering pump assembly 13 before the metering pump assembly 13 closes, and ensuring the safety of the metering pump assembly 13.

[0053] In one embodiment, the reagent detection optocoupler 15 may include a light beam emitter and a light beam receiver, which are respectively arranged on both sides of the first sub-pipeline 121. Then, when the reagent and the bubble pass through the first sub-pipeline 121, the reagent or the bubble can absorb the light beam emitted by the light beam emitter to different degrees, and the light beam receiver can receive the partially absorbed light beam, thereby determining whether the substance passing through the first sub-pipeline 121 is a reagent or a bubble.

[0054] In another embodiment, the distance between the reagent detection optocoupler 15 on the first sub-pipeline 121 and the connection between the first sub-pipeline 121 and the second sub-pipeline 122 is greater than the product of the conveying speed of the bubble in the first sub-pipeline 121 and the control time. As described above, there is a certain time difference from when the reagent detection optocoupler 15 detects a bubble to when the controller controls the metering pump assembly 13 to close, and the control time is the time from when the reagent detection optocoupler 15 detects a bubble in the first sub-pipeline 121 to when the controller controls the metering pump assembly 13 to close.

[0055] To ensure that when the metering pump assembly 13 closes, the bubble is still only in the first sub-pipeline 121 and has not entered the second sub-pipeline 122, and when subsequent bubbles continuously pass through the reagent assembly 11 and enter the first sub-pipeline 121, the bubble can enter the second pipeline 14 through the first sub-pipeline 121, avoiding the situation where the bubble enters the metering pump assembly 13 through the second sub-pipeline 122.

[0056] It can be understood that since the bubble does not enter the second sub-pipeline 122 when the metering pump assembly 13 closes, that is, at this time, the second sub-pipeline 122 is filled with the reagent without bubbles. Therefore, when subsequent bubbles pass through the reagent assembly 11 and enter the first sub-pipeline 121, since the second sub-pipeline 122 is filled with the reagent, the bubble can only enter the second pipeline 14 to enable the second pipeline 14 to accommodate the bubble, improving the efficiency of bubble treatment in the reagent delivery device 1.

[0057] In other embodiments, after the reagent component 11 is replaced, the new reagent in the reagent component 11 will enter the first sub-pipeline 121, flushing the bubbles in the first sub-pipeline 121. The bubbles in the first sub-pipeline 121 burst and disappear, eliminating the need for additional reagent bubble discharge, reducing the reagent consumption of the reagent delivery device 1, and saving reagent costs.

[0058] The reagent detection optocoupler 15 can further detect the reagent passing through the first sub-pipeline 121. When the controller responds to the completion of the replacement of the reagent component 11, the controller controls the reagent detection optocoupler 15 to detect the first sub-pipeline 121. In response to the reagent detection optocoupler 15 detecting the reagent in the first sub-pipeline 121, the metering pump assembly 13 is controlled to start, so as to deliver the reagent to the liquid-using component. This avoids the situation where the replacement operation of the reagent component 11 fails or the reagent has not entered the first sub-pipeline 121, but the metering pump assembly 13 starts, sucking the bubbles originally in the first sub-pipeline 121 into the metering pump assembly 13 through the second sub-pipeline 122, which affects the metering pump assembly 13, improving the safety of the metering pump assembly 13 and the safety and practicability of the reagent delivery device 1.

[0059] Optionally, the metering pump assembly 13 includes a first control valve 131, a metering pump 132, a second control valve 133, a positive pressure source 134, and a negative pressure source 135. Among them, the first control valve 131 and the second control valve 133 can be three-way valves.

[0060] Among them, the first end of the first control valve 131 is connected to the first end of the metering pump 132, the second end of the first control valve 131 is connected to the second sub-pipeline 122, and the third end of the first control valve 131 is connected to the liquid-using component. The positive pressure source 134 is connected to the first end of the second control valve 133, the negative pressure source 135 is connected to the second end of the second control valve 133, and the second end of the metering pump 132 is connected to the second control valve 133.

[0061] Among them, the controller can control the first control valve 131 and the second control valve 133 to open, so that the metering pump assembly 13 starts. Through the cooperation of the components in the metering pump assembly 13, the reagent in the second sub-pipeline 122 is delivered to the liquid-using component.

[0062] Specifically, the controller can control the first control valve 131 to connect the second sub-pipeline 122 and the metering pump 132, and control the second control valve 133 to connect the negative pressure source 135 and the metering pump 132, and then control the negative pressure source 135 to start. The metering pump 132 sucks the reagent in the second sub-pipeline 122 into the metering pump 132.

[0063] Then, the controller controls the first control valve 131 to switch to connect the liquid using assembly and the metering pump 132, and the second control valve 133 to switch to connect the positive pressure source 134 and the metering pump 132. Further, the controller controls the positive pressure source 134 to start, and the metering pump 132 conveys the reagent in the metering pump 132 to the liquid using assembly.

[0064] In one embodiment, the controller controlling the first control valve 131 to close as described above may be that the controller controls the first control valve 131 to neither connect the second sub-pipeline 122 and the metering pump 132 nor connect the metering pump 132 and the liquid using assembly; or the controller controls the first control valve 131 to switch to connect the metering pump 132 and the liquid using assembly to cut off the connection between the second sub-pipeline 122 and the metering pump 132. On the basis of realizing the cut-off relationship between the second sub-pipeline 122 and the metering pump 132, the specific form of the controller controlling the first control valve 131 to close is not limited in this embodiment.

[0065] Optionally, the reagent delivery device 1 further includes a power source assembly 16.

[0066] The power source assembly 16 is connected to the second end of the second pipeline 14, and is used to provide a force for sucking the air bubbles into the second pipeline 14, and the controller is also connected to the power source assembly 16.

[0067] Wherein, when the controller detects an air bubble in the first sub-pipeline 121 in response to the reagent detection optocoupler 15, the controller controls the first control valve 131 and the second control valve 133 to close, and controls the power source assembly 16 to open to suck the air bubble in the first sub-pipeline 121 into the second pipeline 14. By arranging the power source assembly 16 to suck the air bubble at the second end of the second pipeline 14, the air bubble entering the second sub-pipeline 122 is further prevented, and the protection of the metering pump assembly 13 by the reagent delivery device 1 is improved.

[0068] In one embodiment, it may be that the controller first controls the first control valve 131 and the second control valve 133 to close, and then controls the power source assembly 16 to open to avoid the backflow of the reagent in the second sub-pipeline 122 caused by the power source assembly 16; or the controller controls the first control valve 131 and the second control valve 133 to close and simultaneously controls the power source assembly 16 to open to suck the air bubble; the present application does not limit this.

[0069] Specifically, in combination with the metering pump assembly 13 and the power source assembly 16 described above, the reagent delivery process of the reagent delivery device 1 is briefly described as follows:

[0070] When the controller detects that the reagent detection optocoupler 15 detects the reagent in the first sub-pipeline 121, that is, when the remaining amount of the reagent in the reagent component 11 is sufficient at this time, the controller controls the metering pump component 13 to start and controls the power source component 16 to turn off. The metering pump component 13 transports the reagent in the first pipeline 12 to the liquid-using component.

[0071] When the controller detects that the reagent detection optocoupler 15 detects a bubble in the first sub-pipeline 121, that is, when the remaining amount of the reagent in the reagent component 11 is insufficient at this time, the controller controls the metering pump component 13 to turn off and controls the power source component 16 to start. The power source component 16 sucks the bubble into the second pipeline 14. This avoids bubbles entering the metering pump component 13, making it difficult to handle the bubbles in the metering pump component 13 and affecting the transportation of the reagent and the accuracy of subsequent detection of the reagent. It improves the transportation efficiency and practicality of the reagent delivery device 1 for the reagent.

[0072] Furthermore, after the controller detects that the reagent detection optocoupler 15 detects a bubble in the first sub-pipeline 121, determines that the reagent in the reagent component 11 is insufficient and replaces the reagent component 11, the controller also controls the power source component 16 to start (at this time, the metering pump component 13 is in the off state) so that the reagent in the reagent component 11 is transported to the first sub-pipeline 121. When the controller detects that the reagent detection optocoupler 15 detects the reagent in the first sub-pipeline 121, after a preset time, it controls the power source component 16 to turn off and controls the metering pump component 13 to start so that the metering pump component 13 transports the reagent to the liquid-using component.

[0073] Among them, the preset time is greater than or equal to the time for the reagent to reach the connection between the first sub-pipeline 121 and the second sub-pipeline 122 from the reagent detection optocoupler 15 of the first sub-pipeline 121. When the preset time is equal to the time for the reagent to reach the connection between the first sub-pipeline 121 and the second sub-pipeline 122 from the reagent detection optocoupler 15 of the first sub-pipeline 121, when the metering pump component 13 starts, the reagent fills the intersection of the reagents in the first sub-pipeline 121 and the second sub-pipeline 122, the first pipeline 12 is filled with the reagent, and the reagent eliminates the bubbles in the first sub-pipeline 121 to prevent the bubbles from mixing with the reagent and entering the metering pump component 13. The bubbles in the second pipeline 14 will also burst and disappear over time.

[0074] When the preset time is greater than the time for the reagent to reach the connection between the first sub-pipeline 121 and the second sub-pipeline 122 from the reagent detection optocoupler 15 of the first sub-pipeline 121, that is, before the metering pump assembly 13 is turned on, the reagent fills the first sub-pipeline 121 and the reagent in the second sub-pipeline 122 meets, and part of the reagent will enter the second pipeline 14, eliminating the bubbles in the second pipeline 14, improving the elimination efficiency of the bubbles in the first sub-pipeline 121 and the second pipeline 14, preventing the bubbles from entering the metering pump assembly 13, and improving the practicability of the reagent delivery device 1.

[0075] In summary, the reagent delivery device 1 provided by the embodiment of the present application includes a reagent assembly 11, a first pipeline 12, a metering pump assembly 13, a second pipeline 14, a reagent detection optocoupler 15, a power source assembly 16, and a controller. The controller determines the remaining amount of the reagent in the reagent assembly 11 through the reagent detection optocoupler 15. When the reagent in the reagent assembly 11 is sufficient, the controller controls the metering pump assembly 13 to turn on to deliver the reagent to the liquid-using assembly through the first pipeline. When the reagent in the reagent assembly 11 is insufficient and bubbles are generated, the controller controls the metering pump assembly 13 to turn off to prevent the bubbles from entering the metering pump assembly 13, and controls the power source assembly 16 to turn on to suck the bubbles into the second pipeline 14 to prevent the bubbles from entering the metering pump assembly 13. The reagent delivery device 1 does not need to perform bubble removal treatment on the metering pump assembly 13, reducing the time and difficulty of removing bubbles by the reagent delivery device 1 and improving the reagent delivery efficiency of the reagent delivery device 1.

[0076] Moreover, the distance between the reagent detection optocoupler 15 on the first sub-pipeline 121 and the connection between the first sub-pipeline 121 and the second sub-pipeline 122 is greater than the product of the conveying speed of the bubbles in the first sub-pipeline 121 and the control time, ensuring that the bubbles will not enter the second sub-pipeline 122 before the controller controls the metering pump assembly 13 to turn off, further preventing the bubbles from entering the metering pump assembly 13 through the second sub-pipeline 122 and improving the safety of the metering pump assembly 13.

[0077] Furthermore, after the reagent assembly 11 is replaced, the power source assembly 16 sucks the reagent in the reagent assembly 11 to at least fill the first sub-pipeline 121, and the reagent eliminates the bubbles in the first sub-pipeline 121. Then the controller controls the metering pump assembly 13 to turn on to deliver the reagent to the liquid-using assembly, improving the reagent delivery efficiency of the reagent delivery device 1.

[0078] The present application also provides a hematology analyzer (not shown in the figure), including a reagent delivery device 1 and a liquid-using assembly. The reagent delivery device 1 is connected to the liquid-using assembly to deliver the reagent to the liquid-using assembly, and the liquid-using assembly receives the reagent and uses the reagent for detection operations.

[0079] The above are only the embodiments of the present application, and do not thus limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of the present application, or directly or indirectly applied in other related technical fields, shall similarly be included within the patent protection scope of the present application.

Claims

1. A reagent delivery device, characterized in that, Comprising: A reagent component for storing reagents; A first pipeline, one end of the first pipeline being connected to the reagent component; A metering pump component, the other end of the first pipeline being connected to a liquid-using component through the metering pump component; A second pipeline, the first end of the second pipeline being connected to the first pipeline; A controller, connected to the metering pump component, the controller being configured to: Control the metering pump component to start, and convey the reagent in the reagent component to the liquid-using component through the first pipeline; In response to detecting air bubbles in the first pipeline, determine that the reagent in the reagent component is insufficient, control the metering pump component to close, convey the air bubbles in the first pipeline to the second pipeline, and replace the reagent component to replenish the reagent.

2. The reagent delivery device according to claim 1, wherein The first pipeline includes a first sub-pipeline and a second sub-pipeline; one end of the first sub-pipeline is connected to the reagent component, the other end of the first sub-pipeline is connected to one end of the second sub-pipeline, and the other end of the second sub-pipeline is connected to the metering pump component; The reagent delivery device further includes a reagent detection optocoupler disposed on the first sub-pipeline, and the controller is further connected to the reagent detection optocoupler. Wherein, the controller is further configured to: Control the reagent detection optocoupler to detect the first sub-pipeline. In response to the reagent detection optocoupler detecting the air bubbles in the first sub-pipeline, control the metering pump component to close so that the air bubbles are conveyed to the second pipeline.

3. The reagent delivery device according to claim 2, wherein, After the reagent component is replaced, the controller is further configured to: Control the reagent detection optocoupler to detect the first sub-pipeline. In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the metering pump component to start to convey the reagent to the liquid-using component.

4. The reagent delivery device according to claim 3, wherein, One end of the second pipeline is connected to the connection point of the first sub-pipeline and the second sub-pipeline. Wherein, The distance between the reagent detection optocoupler on the first sub-pipeline and the connection point of the first sub-pipeline and the second sub-pipeline is greater than the product of the conveying speed of the air bubbles in the first sub-pipeline and the control time, where the control time is the time from the reagent detection optocoupler detecting the air bubbles in the first sub-pipeline to the controller controlling the metering pump component to close.

5. The reagent delivery device according to claim 3, wherein The metering pump component includes a first control valve, a metering pump, a second control valve, a positive pressure source, and a negative pressure source; Wherein, the first end of the first control valve is connected to the first end of the metering pump, the second end of the first control valve is connected to the second sub-pipeline, and the third end of the first control valve is connected to the liquid-using component; The positive pressure source is connected to the first end of the second control valve, the negative pressure source is connected to the second end of the second control valve, and the second end of the metering pump is connected to the third end of the second control valve; Wherein, the controller is further configured to control the first control valve and the second control valve to open so that the metering pump component starts to convey the reagent in the second sub-pipeline to the liquid-using component.

6. The reagent delivery device according to claim 5, characterized in that, The controller is further configured to: Control the first control valve to connect the second sub-pipeline and the metering pump, and control the second control valve to connect the negative pressure source and the metering pump, thereby controlling the start of the negative pressure source, and the metering pump sucks the reagent in the second sub-pipeline into the metering pump; Control the first control valve to connect the liquid-using assembly and the metering pump, and control the second control valve to connect the positive pressure source and the metering pump, thereby controlling the start of the positive pressure source, and the metering pump transports the reagent in the metering pump to the liquid-using assembly.

7. The reagent delivery device according to claim 5, characterized in that, The reagent delivery device further includes a power source assembly connected to the second end of the second pipeline, and the controller is also connected to the power source assembly for: In response to the reagent detection optocoupler detecting the bubble in the first sub-pipeline, control the first control valve and the second control valve to close, and control the power source assembly to turn on to suck the bubble in the first sub-pipeline into the second pipeline.

8. The reagent delivery device according to claim 7, characterized in that, The controller is further used for: In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the metering pump assembly to turn on, control the power source assembly to turn off, and the metering pump assembly transports the reagent in the first pipeline to the liquid-using assembly; In response to the reagent detection optocoupler detecting the bubble in the first sub-pipeline, control the metering pump assembly to turn off, control the power source assembly to turn on, and the power source assembly sucks the bubble into the second pipeline.

9. The reagent delivery device according to claim 7, wherein, In response to the completion of the replacement of the reagent assembly, the controller is further used for: Control the power source assembly to turn on so that the reagent in the reagent assembly is transported to the first sub-pipeline; In response to the reagent detection optocoupler detecting the reagent in the first sub-pipeline, control the power source assembly to turn off after a preset time, and control the metering pump assembly to turn on so that the metering pump assembly transports the reagent to the liquid-using assembly; Wherein, the preset time is greater than or equal to the time for the reagent to reach the connection between the first sub-pipeline and the second sub-pipeline from the reagent detection optocoupler of the first sub-pipeline.

10. A hematology analyzer, characterized in that, Comprising the reagent delivery device and the liquid-using assembly according to any one of claims 1-9, the reagent delivery device is connected to the liquid-using assembly to deliver the reagent to the liquid-using assembly.

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