Hydrophilic coating groove round hole drainage tube and preparation method thereof

Abstract

The invention relates to the technical field of medical instruments, in particular to a hydrophilic coating groove round hole drainage tube and a preparation method thereof, and the preparation method comprises the following steps: S1, preparing a groove round hole drainage tube; s2, preparing a bottom layer coating solution; s3, preparing a surface layer coating solution; and S4, preparing the hydrophilic coating groove round hole drainage tube. According to the hydrophilic coating groove round hole drainage tube and the preparation method thereof, the outer wall of the drainage tube is coated with the hydrophilic coating, after the outer wall hydrophilic coating is activated, the friction resistance between the drainage tube and human tissue can be remarkably reduced, the inner wall of the drainage tube is coated with the hydrophilic coating, after the inner wall hydrophilic coating is activated, the flow resistance between liquid and the inner wall of the drainage tube can be reduced, and the drainage tube has the advantages that the flow resistance is reduced; due to the unique groove round hole design, blocking prevention, bending resistance and extrusion resistance are achieved, the drainage efficiency of the drainage tube is remarkably improved, and continuity and stability of drainage can be guaranteed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a hydrophilic-coated groove round-hole drainage tube and a preparation method thereof. Background Art

[0002] After surgery, the drainage tube uses the continuous negative pressure generated by the negative pressure drainage device to draw out the gas and liquid at the surgical site, which can effectively control the amount of wound exudate, avoid subcutaneous accumulation or other complications caused by fluid accumulation, such as hematoma and seroma. The negative pressure environment can promote the formation of new blood vessels, increase local blood supply, and at the same time stimulate the generation of granulation tissue, accelerate the wound healing process, and improve the rehabilitation effect of patients.

[0003] Currently, the common drainage tubes on the market mainly include perforated round-tube drainage tubes and cross-groove round-hole drainage tubes, whose material is silicone rubber polymer material with strong hydrophobicity. During clinical use, they will generate a large frictional resistance with the skin or tissue, causing pain to the patient during tube removal or large friction with the tissue, resulting in injury and many other adverse complications. The production process of the perforated round-tube drainage tube is simple, but it has poor drainage of viscous pus and the drainage holes are easily blocked. For the cross-groove round-hole drainage tube, due to the presence of reinforcing ribs at the connection between the groove and the tube body, the internal flow area at the connection between the groove and the tube body is suddenly reduced, thus having a greater impact on the drainage rate, and there is also a problem of poor drainage of viscous pus. Therefore, there is an urgent need for a hydrophilic-coated groove round-hole drainage tube and a preparation method thereof to improve the above problems. Summary of the Invention

[0004] The purpose of the present invention aims to solve at least one of the above technical defects.

[0005] Therefore, an object of the present invention is to provide a hydrophilic-coated groove round-hole drainage tube and a preparation method thereof to solve the problems mentioned in the background art and overcome the deficiencies in the prior art.

[0006] 1. To achieve the above object, an embodiment of one aspect of the present invention provides a hydrophilic-coated groove round-hole drainage tube and a preparation method thereof, including the following steps:

[0007] S1: Mix the raw material solid silicone rubbers A and B and the developer silicone rubber, then put them into an extruder for extrusion. Intermittent punching is performed on the part between the transition section and the tube body of the groove round-hole drainage tube to prepare the groove round-hole drainage tube, and then printing and drying of the marking points are carried out;

[0008] S2: Mix tetrahydrofuran, diacetone alcohol, isopropanol, silane coupling agent γ-glycidoxypropyltrimethoxysilane, and polyurethane acrylate to prepare the bottom layer coating liquid;

[0009] S3: Mix tetrahydrofuran, diacetone alcohol, n-heptane, silane coupling agent N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, polyurethane acrylate, and hydrophilic polymer to prepare a surface layer coating solution.

[0010] S4: Immerse the grooved round hole drainage tube into the bottom layer coating solution and the surface layer coating solution respectively, coat and cure the drainage tube to prepare a hydrophilic coating grooved round hole drainage tube.

[0011] The present invention is further configured as follows: In step S2, first add 47.9 - 52.6 parts of the tetrahydrofuran, 10.1 - 14.2 parts of diacetone alcohol, and 31.2 - 34.4 parts of isopropanol into a reaction vessel and place it on a magnetic stirrer to stir evenly. Then add 0.6 - 1.3 parts of silane coupling agent γ-glycidoxypropyltrimethoxysilane and 2.3 - 4.2 parts of polyurethane acrylate into the reaction vessel and stir for 2 h until completely dissolved to obtain the bottom layer coating solution.

[0012] By adopting the above technical solution, the bottom layer coating solution can be obtained.

[0013] The present invention is further configured as follows: In step S3, first add 46.4 - 49.8 parts of the tetrahydrofuran, 8.7 - 10.3 parts of diacetone alcohol, and 35.7 - 38.1 parts of n-heptane into a reaction vessel and place it on a magnetic stirrer to stir evenly. Then add 0.5 - 0.9 parts of silane coupling agent N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, 1.5 - 2.5 parts of polyurethane acrylate, and 2.5 - 3.6 parts of hydrophilic polymer into the reaction vessel and stir for 3 h until completely dissolved to obtain the surface layer coating solution.

[0014] By adopting the above technical solution, the surface layer coating solution can be obtained.

[0015] The present invention is further configured as follows: The inner and outer walls of the drainage tube are both coated with a hydrophilic coating. The drainage tube includes a tube body. One side of the tube body is provided with a round hole section, the round hole section is provided with drainage holes, one side of the round hole section is provided with a transition section, and one side of the transition section is provided with a grooved section. The grooved section includes a connecting pipe, and a reinforcing rib is arranged inside the connecting pipe. A groove is formed on the outer surface of the tube body, a developing wire is arranged inside the groove, and a marking point is arranged on the outer surface of the tube body.

[0016] By adopting the above technical solution, the surface friction coefficient of the drainage tube can be greatly reduced, and the flow resistance between the liquid and the inner wall of the tube can be reduced.

[0017] The present invention is further configured as follows: The drainage tube is made of medical polymer material silicone rubber. The hydrophilic coatings on the inner and outer walls of the drainage tube are composed of hydrophilic polymers, and the hydrophilic polymer is selected from one or two of polyvinylpyrrolidone and polyacrylamide.

[0018] By adopting the above technical solution, the hydrophilic coating can be activated by water to generate a lubricating effect.

[0019] The present invention is further configured such that: the drainage holes penetrate through the circular hole section, and the drainage holes are staggered and evenly distributed on the surface of the circular hole section.

[0020] By adopting the above technical solution, gases and liquids can be attracted into the tube body in all directions.

[0021] The present invention is further configured such that: drainage grooves are provided on both sides of the reinforcing rib, the reinforcing rib is in a straight shape, and the reinforcing rib is fixedly connected to the connecting pipe.

[0022] By adopting the above technical solution, large particles can be attracted into the tube body.

[0023] The present invention is further configured such that: the reinforcing rib is in an "I" shape, a "trident" shape or a "cross" shape.

[0024] By adopting the above technical solution, the applicable range of the drainage tube can be expanded.

[0025] The present invention is further configured such that: the groove section is fixedly connected to the transition section, the transition section is fixedly connected to the circular hole section, and the circular hole section is fixedly connected to the tube body.

[0026] By adopting the above technical solution, particulate matters, liquids, etc. can be drained out of the body.

[0027] The present invention is further configured such that: the groove extends to the groove section, and the developer line is fixedly connected to the groove.

[0028] By adopting the above technical solution, it is convenient to observe the drainage tube catheterization under fluoroscopy.

[0029] In summary, the beneficial technical effects of the present invention are as follows:

[0030] 1. For the hydrophilic coating groove circular hole drainage tube and its preparation method, the outer wall of the drainage tube is coated with a hydrophilic coating. When the hydrophilic coating contacts tissue fluid, body fluid or pus, it is activated to generate a lubricating effect, which can greatly reduce the surface friction coefficient of the drainage tube, relieve the pain or damage caused to the patient during catheterization and tube removal. At the same time, the hydrophilic coating coated on the inner wall of the tube can reduce the flow resistance between the liquid and the inner wall of the tube for viscous pus, making the drainage smoother;

[0031] 2. For the hydrophilic coating groove circular hole drainage tube and its preparation method, the surface of the hydrophilic coating is smooth, which greatly reduces the adsorption of cells and proteins on the surface of the tube body, is not conducive to the attachment and growth of bacteria, and greatly reduces the possibility of infection, providing a safer environment for the postoperative recovery of patients;

[0032] 3. The hydrophilic coating groove round hole drainage tube and its preparation method are provided with a groove section and a round hole section. The inside of the groove section is designed with reinforcing ribs, which have the advantages of anti-blocking, anti-bending and anti-extrusion. The synergistic effect of the grooves and round holes greatly increases the drainage area and the liquid flow channel, enabling the liquid to be led out of the body more quickly and smoothly, greatly enhancing the drainage rate, promoting wound healing and shortening the patient's recovery time.

[0033] 4. The hydrophilic coating groove round hole drainage tube and its preparation method. The staggered distribution mode of the drainage holes and the drainage effect of the long strip grooves can effectively prevent the drainage tube from being blocked by tissue debris, blood clots, etc., ensuring the continuity and stability of drainage.

[0034] 5. The hydrophilic coating groove round hole drainage tube and its preparation method. The preparation method of the coating liquid is simple. For the silicone rubber material groove round hole drainage tube, dip coating and heat curing methods are adopted. There is no need for cumbersome pretreatment steps before dip coating, and the operation is simple and convenient, with strong practicability.

[0035] Additional aspects and advantages of the present invention will be given in part in the following description, become apparent in part from the following description, or be understood through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] The above and / or additional aspects and advantages of the present invention will become apparent and be readily understood from the description of the embodiments in conjunction with the following drawings, wherein:

[0037] Figure 1 is a schematic structural diagram of the present invention;

[0038] Figure 2 is a schematic structural diagram of the tube body of the present invention;

[0039] Figure 3 is a schematic cross-sectional structural diagram of the tube body of the present invention;

[0040] Figure 4 is a schematic structural diagram of the I-shaped reinforcing rib of the present invention;

[0041] Figure 5 is a schematic structural diagram of the three-pronged reinforcing rib of the present invention;

[0042] Figure 6 is a schematic structural diagram of the cross-shaped reinforcing rib of the present invention.

[0043] In the figure: 1, tube body; 2, round hole section; 3, drainage hole; 4, transition section; 5, groove section; 6, connecting tube; 7, reinforcing rib; 8, groove; 9, developer line; 10, drainage groove; 11, marking point; 12, hydrophilic coating. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0044] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0045] Embodiment 1

[0046] A hydrophilic coating groove round hole drainage tube and its preparation method disclosed by the present invention include the following steps:

[0047] S1: First, put the raw material solid silicone rubbers A and B, and the developing silicone rubber into a mixer in a certain proportion for uniform mixing, then put them into an extruder to extrude an "I-shaped" tube blank, and then obtain an "I-shaped" groove round hole drainage tube through a series of processes such as vulcanization and cutting. Punch holes alternately in the part between the transition section 4 and the tube body 1 of the "I-shaped" groove round hole drainage tube to obtain a groove round hole drainage tube, and then perform printing and drying of the marking point 11. After the whole drainage tube is cleaned, apply and cure the hydrophilic coating 12.

[0048] S2: First, add 52.6 parts of tetrahydrofuran, 10.1 parts of diacetone alcohol, and 34.4 parts of isopropanol into a reaction vessel and place it on a magnetic stirrer for uniform stirring. Then, add 0.6 part of the silane coupling agent γ-glycidoxypropyltrimethoxysilane and 2.3 parts of polyurethane acrylate into the reaction vessel and stir for 2 h until completely dissolved to obtain a bottom layer coating solution.

[0049] S3: Add 49.8 parts of tetrahydrofuran, 9.5 parts of diacetone alcohol, and 35.7 parts of n-heptane into a reaction vessel and place it on a magnetic stirrer for uniform stirring. Then, add 0.5 part of the silane coupling agent N-aminoethyl-γ-aminopropyltrimethoxysilane, 1.5 parts of polyurethane acrylate, and 3.0 parts of polyvinylpyrrolidone into the reaction vessel and stir for 3 h until completely dissolved to obtain a surface layer coating solution.

[0050] S4: Immerse the cleaned and dried "I-shaped" groove round hole drainage tube in the bottom layer coating solution for 40 s to enable the bottom layer coating solution to fully infiltrate the inner and outer walls of the drainage tube. Take it out and dry it for 60 s, then vertically hang it in an oven at 60 °C for 3 h of curing. Then, immerse the groove round hole drainage tube after bottom layer curing in the surface layer coating solution for 40 s, take it out and dry it for 120 s, and then vertically hang it in an oven at 60 °C for 5 h of curing, that is, complete the preparation of the "I-shaped" hydrophilic coating 12 groove round hole drainage tube.

[0051] Refer to Figures 1 to 6, hydrophilic coatings 12 are applied to both the inner and outer walls of the drainage tube. The drainage tube includes a tube body 1. One side of the tube body 1 is provided with a round hole section 2. In this embodiment, the tube body 1 and the round hole section 2 are integrally formed. The round hole section 2 is provided with drainage holes 3. One side of the round hole section 2 is provided with a transition section 4, which is integrally formed with the round hole section 2. One side of the transition section 4 is provided with a groove section 5, which is integrally formed with the transition section 4. The groove section 5 includes a connecting tube 6. A reinforcing rib 7 is arranged inside the connecting tube 6, which can support the connecting tube 6. A groove 8 is formed on the outer surface of the tube body 1. A developing wire 9 is arranged inside the groove 8 and is fixedly connected to the tube body 1 through the groove 8. Marking points 11 are arranged on the outer surface of the tube body 1, which can greatly reduce the surface friction coefficient of the drainage tube, relieve the pain or injury caused to the patient during catheter placement and removal, and can reduce the flow resistance between the liquid and the inner wall of the tube, making the drainage smoother. The drainage tube is made of medical polymer material silicone rubber. The hydrophilic coatings 12 on the inner and outer walls of the drainage tube are composed of hydrophilic polymers. The hydrophilic polymers are selected from one or two of polyvinylpyrrolidone and polyacrylamide, which can activate the hydrophilic coatings 12 by water and generate a lubricating effect, and can greatly reduce the surface friction coefficient of the drainage tube.

[0052] Referring to Figures 1 to 6 , the drainage holes 3 penetrate through the round hole section 2, and the drainage holes 3 are staggered and evenly distributed on the surface of the round hole section 2, which can attract gas and liquid into the tube body 1, and then can discharge the liquid and gas out of the body. Drainage grooves 10 are arranged on both sides of the reinforcing rib 7. The connecting tube 6 is divided into different drainage grooves 10 by the reinforcing rib 77. The reinforcing rib 7 is in a straight shape and is fixedly connected to the connecting tube 6, which can attract large particles into the tube body 1 and then discharge them out of the body. The reinforcing rib 7 is in a "work" shape, "trident" shape or "cross" shape, which can expand the application range of the drainage tube. The groove section 5 is fixedly connected to the transition section 4, the transition section 4 is fixedly connected to the round hole section 2, and the round hole section 2 is fixedly connected to the tube body 1, which can drain particulate matter, liquid, etc. out of the body. The groove 8 extends to the groove section 5, and then the developing wire 9 can extend to the groove section 5, and the developing wire 9 is fixedly connected to the groove 8, which can facilitate the observation of the catheter placement length of the drainage tube and then facilitate the use of the drainage tube.

[0053] Embodiment 2

[0054] The preparation method of the hydrophilic coating groove round hole drainage tube is as follows: First, put the raw material solid silicone rubbers A and B and the developing silicone rubber into a mixer according to a certain proportion and mix them evenly, then put them into an extruder to extrude a "trident" tube blank, and then obtain a "trident" groove round hole drainage tube through a series of processes such as vulcanization and cutting. Punch holes staggered between the transition section 4 and the tube body 1 of the "trident" groove round hole drainage tube to obtain a groove round hole drainage tube, and then print and dry the marking points 11. After the whole drainage tube is cleaned, the hydrophilic coating 12 is coated and cured.

[0055] The preparation method of the hydrophilic coating liquid and the coating and curing process of the whole drainage tube are as follows:

[0056] S2 Preparation of the bottom layer coating liquid

[0057] First, add 51.3 parts of tetrahydrofuran, 12.9 parts of diacetone alcohol, and 31.2 parts of ethanol into a reaction vessel, place it on a magnetic stirrer and stir evenly. Then add 1.3 parts of silane coupling agent γ-glycidoxypropyltrimethoxysilane and 3.3 parts of polyurethane acrylate into the reaction vessel and stir for 2 h until completely dissolved to obtain the bottom layer coating liquid.

[0058] S3 Preparation of the surface layer coating liquid

[0059] Add 46.4 parts of tetrahydrofuran, 10.3 parts of diacetone alcohol, and 38.1 parts of n-heptane into a reaction vessel, place it on a magnetic stirrer and stir evenly. Then add 0.7 part of silane coupling agent N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, 2.0 parts of polyurethane acrylate, and 2.5 parts of polyacrylamide into the reaction vessel and stir for 3 h until completely dissolved to obtain the surface layer coating liquid.

[0060] S4 Coating and curing of the drainage tube

[0061] Immerse the cleaned and dried "trident-shaped" grooved round-hole drainage tube in the bottom layer coating liquid for 50 s to allow the bottom layer coating liquid to fully infiltrate the inner and outer walls of the drainage tube. Take it out and dry it for 80 s, then vertically hang it in an oven at 70 °C for curing for 2 h. Then immerse the grooved round-hole drainage tube with the bottom layer cured in the surface layer coating liquid for 50 s, take it out and dry it for 150 s, and then vertically hang it in an oven at 70 °C for curing for 4 h to complete the preparation of the "trident-shaped" hydrophilic coating 12 grooved round-hole drainage tube.

[0062] Example 3

[0063] The preparation method of the hydrophilic coating grooved round-hole drainage tube is as follows: First, put the raw material solid silicone rubbers A and B and the developing silicone rubber into a mixer according to a certain ratio and mix them evenly. Then put them into an extruder to extrude a "cross-shaped" tube blank, and then obtain a "cross-shaped" grooved round-hole drainage tube through a series of processes such as vulcanization and cutting. Make staggered holes in the part between the transition section 4 and the tube body 1 of the "cross-shaped" grooved round-hole drainage tube to obtain a grooved round-hole drainage tube, and then perform printing and drying of the marking point 11. After cleaning the tube body 1, perform hydrophilic coating and curing.

[0064] The preparation method of the hydrophilic coating liquid and the coating and curing process of the whole drainage tube are as follows:

[0065] S1 Preparation of the bottom layer coating liquid

[0066] First, add 47.9 parts of tetrahydrofuran, 14.2 parts of diacetone alcohol, and 32.8 parts of isopropanol into a reaction vessel, place it on a magnetic stirrer and stir evenly. Then, add 0.9 part of silane coupling agent γ-glycidoxypropyltrimethoxysilane and 4.2 parts of polyurethane acrylate into the reaction vessel and stir for 2 h until completely dissolved to obtain the bottom layer coating solution.

[0067] S2 Preparation of surface layer coating solution

[0068] Add 47.8 parts of tetrahydrofuran, 8.7 parts of diacetone alcohol, and 36.5 parts of n-heptane into a reaction vessel, place it on a magnetic stirrer and stir evenly. Then, add 0.9 part of silane coupling agent N-aminoethyl-γ-aminopropyltrimethoxysilane, 2.5 parts of polyurethane acrylate, 1.8 parts of polyvinylpyrrolidone, and 1.8 parts of polyacrylamide into the reaction vessel and stir for 4 h until completely dissolved to obtain the surface layer coating solution.

[0069] S3 Coating and curing of drainage tube

[0070] Immerse the cleaned and dried "cross-shaped" grooved round-hole drainage tube into the bottom layer coating solution for 30 s to allow the bottom layer coating solution to fully infiltrate the inner and outer walls of the drainage tube. After taking it out, dry it for 50 s, then vertically hang it in an oven at 60 °C for 4 h of curing. Then, immerse the grooved round-hole drainage tube with the bottom layer cured into the surface layer coating solution for 30 s, take it out and dry it for 110 s, and then vertically hang it in an oven at 60 °C for 6 h of curing, thus completing the preparation of the "cross-shaped" hydrophilic coating 12 grooved round-hole drainage tube.

[0071] Comparative example 1

[0072] Put raw material solid silicone rubbers A and B and developing silicone rubber into a mixer according to a certain proportion and mix evenly. Then, put it into an extruder to extrude an "I-shaped" tube blank, and then obtain an "I-shaped" grooved round-hole drainage tube through a series of processes such as vulcanization and cutting. Replace the die head of the extruder and successively extrude "trident-shaped" and "cross-shaped" grooved round-hole drainage tubes.

[0073] Comparative example 2

[0074] Put raw material solid silicone rubbers A and B and developing silicone rubber into a mixer according to a certain proportion and mix evenly. Then, put it into an extruder to extrude an "I-shaped" tube blank, and then obtain an "I-shaped" grooved round-hole drainage tube through a series of processes such as vulcanization and cutting. For the "I-shaped" grooved round-hole drainage tube, make staggered holes in the part between the transition section 4 and the tube body 1 to obtain an "I-shaped" grooved round-hole drainage tube, and then perform printing and drying of the marking point 11. Replace the die head of the extruder and successively extrude "trident-shaped" and "cross-shaped" grooved round-hole drainage tubes. Then, make staggered holes in the part between the transition section 4 and the tube body 1 of the grooved round-hole drainage tube to obtain "trident-shaped" and "cross-shaped" grooved round-hole drainage tubes.

[0075] The lubricity, unobstructedness, and smoothness of Example 1, Example 2, Example 3, Comparative Example 1, and Comparative Example 2 were tested as follows:

[0076] For lubricity, the friction coefficient was tested according to the test method specified in the "YY / T 1536-2017 Standard Test Model for Evaluating the Surface Sliding Performance of Non-Vascular Catheters".

[0077] For unobstructedness, the unobstructedness test was carried out with deionized water according to the test method specified in Appendix G of "YY / T 0489-2023 Disposable Sterile Drainage Catheters and Auxiliary Instruments".

[0078] The smoothness test method was to test the inner wall of the tube body 1. For the smoothness test of the inner wall of the tube body 1, simulated sputum was used to represent viscous pus. The simulated sputum was injected into the inside of the tube body 1. By applying a certain pressure, the simulated sputum was made to flow through the drainage tube. During the drainage process, the amount of the drained fluid at different time points was recorded, the drainage speed was calculated, and at the same time, the flow state of the simulated sputum in the drainage tube was observed, such as whether there was a phenomenon of adhering to the tube wall.

[0079] The test results are shown in the following table:

[0080]

[0081]

[0082] By analyzing the test results, compared with Example 1, Example 2, Example 3, Comparative Example 1, and Comparative Example 2, the friction coefficient was significantly reduced by more than 95%, and the lubricity of the entire drainage tube was significantly improved. The unobstructedness of the grooved round-hole drainage tube in Comparative Example 1 was 560 mL / min. In Comparative Example 2, after drilling a hole between the grooved transition section 4 and the tube body 1, the unobstructedness was increased to 705 mL / min, and the unobstructedness index was significantly increased by 25.9%. In Example 1, Example 2, and Example 3, due to the hydrophilic coating 12 being coated on the inner wall of the tube body 1, the unobstructedness was slightly improved compared with Comparative Example 2. However, when analyzing the smoothness index for viscous pus, there were significant changes in Example 1, Example 2, and Example 3 compared with Comparative Example 1 and Comparative Example 2, and no phenomenon of adhering to the tube wall was observed when observing the flow state of the simulated sputum. In summary, this hydrophilic coating 12 grooved round-hole drainage tube can greatly reduce the surface friction coefficient of the drainage tube. The grooved round-hole design greatly increases the drainage area and the liquid flow channel, enabling the liquid to be drawn out of the body more quickly and smoothly, and significantly enhancing the drainage rate.

[0083] The implementation principle of this embodiment is:

[0084] The hydrophilic-coated grooved round-hole drainage tube is provided with a tube body 1. When using this grooved round-hole drainage tube, medical staff insert the drainage tube into the end of the tube body 1 with a guiding needle. The guiding needle punctures through the skin and pulls out the drainage tube to the marking point 11 and stops. At this time, the grooved section 5, the transition section 4, and the round-hole section 2 of the drainage tube are placed at the part of the human body that needs drainage. During this process, the hydrophilic coating 12 on the outer wall of the tube body 1 comes into contact with the moisture in human tissues, reducing the friction during catheter placement. The tube body 1 is connected to an external negative-pressure device, and negative pressure can be generated inside the tube body 1. Under the action of negative pressure, the drainage grooves 10 in the grooved section 5 and the drainage holes 3 in the round-hole section 2 can attract the gas and liquid in human tissues in all directions to the inside, and finally flow into the tube body 1 and be drained out of the body. Since the inner and outer walls of the grooved section 5, the transition section 4, and the round-hole section 2 are all coated with the hydrophilic coating 12, when this hydrophilic coating 12 comes into contact with the pus, blood, etc. of human tissues, the coating is activated by the moisture and has a lubricating function, significantly reducing the friction with human tissues during tube removal. Also, because the inner wall of the tube body 1 is coated with the hydrophilic coating 12, the viscous pus is attracted to the inside of the tube body 1 after passing through the grooved section 5 and the round-hole section 2, wetting the hydrophilic coating 12 and reducing the friction between the viscous pus and the inner wall of the tube body 1, so that the viscous pus can be drained out of the body more smoothly.

[0085] In summary, the beneficial technical effects of the present invention are as follows:

[0086] 1. For the hydrophilic-coated grooved round-hole drainage tube and its preparation method, the outer wall of the drainage tube is coated with a hydrophilic coating. When the hydrophilic coating comes into contact with tissue fluid, body fluid or pus, it is activated and generates a lubricating effect, which can greatly reduce the surface friction coefficient of the drainage tube, relieve the pain or damage suffered by the patient during catheter placement and tube removal. At the same time, the hydrophilic coating coated on the inner wall of the tube body is aimed at viscous pus, which can reduce the flow resistance between the liquid and the inner wall of the tube, making the drainage smoother;

[0087] 2. For the hydrophilic-coated grooved round-hole drainage tube and its preparation method, the surface of the hydrophilic coating is smooth, greatly reducing the adsorption of cells, proteins, etc. on the surface of the tube body, being not conducive to the attachment and growth of bacteria, and greatly reducing the possibility of infection to provide a safer environment for the postoperative recovery of patients;

[0088] 3. For the hydrophilic-coated grooved round-hole drainage tube and its preparation method, it is provided with a grooved section and a round-hole section. The inside of the grooved section is designed with reinforcing ribs, which has the advantages of anti-blocking, anti-bending, and anti-extrusion. The synergistic effect of the grooves and the round holes greatly increases the drainage area and the liquid flow channel, enabling the liquid to be led out of the body more quickly and smoothly, greatly enhancing the drainage rate, promoting wound healing, and shortening the patient's recovery time;

[0089] 4. The hydrophilic coating groove round-hole drainage tube and its preparation method, the staggered distribution mode of drainage holes and the drainage effect of long grooves can effectively prevent the drainage tube from being blocked by tissue debris, blood clots, etc., and ensure the continuity and stability of drainage;

[0090] 5. The hydrophilic coating groove round-hole drainage tube and its preparation method have a simple coating liquid preparation method. For the silicone rubber material groove round-hole drainage tube, dip coating and heat curing methods are adopted. There is no need for complicated pretreatment steps before dip coating, and the operation is simple and convenient, with strong practicability.

[0091] The embodiments of this specific implementation manner are all preferred embodiments of the present invention, and do not limit the protection scope of the present invention accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of the present invention should be covered within the protection scope of the present invention.

Claims

1. A preparation method of a hydrophilic coating groove round hole drainage tube, characterized in that: It includes the following steps: S1: Mix the raw material solid silicone rubbers A and B and the developing silicone rubber, then put them into an extruder for extrusion. Intermittent punching is carried out on the part between the groove round-hole drainage tube transition section (4) and the tube body (1) to prepare a groove round-hole drainage tube, and then printing and drying of the marking points (11) are carried out; S2: Mix tetrahydrofuran, diacetone alcohol, isopropanol, silane coupling agent γ-glycidoxypropyltrimethoxysilane, and polyurethane acrylate to prepare a bottom layer coating solution; S3: Mix tetrahydrofuran, diacetone alcohol, n-heptane, silane coupling agent N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, polyurethane acrylate, and hydrophilic polymer to prepare a surface layer coating solution; S4: Immerse the groove round-hole drainage tube into the bottom layer coating solution and the surface layer coating solution respectively, and coat and cure the drainage tube to prepare a hydrophilic coating groove round-hole drainage tube.

2. The preparation method of a hydrophilic coating groove round hole drainage tube according to claim 1, characterized in that: In step S2, first add 47.9 - 52.6 parts of the tetrahydrofuran, 10.1 - 14.2 parts of the diacetone alcohol, and 31.2 - 34.4 parts of the isopropanol into a reaction vessel and place it on a magnetic stirrer to stir evenly. Then add 0.6 - 1.3 parts of the silane coupling agent γ-glycidoxypropyltrimethoxysilane and 2.3 - 4.2 parts of the polyurethane acrylate into the reaction vessel and stir for 2 h until completely dissolved to obtain the bottom layer coating solution.

3. The preparation method of a hydrophilic coating groove round hole drainage tube according to claim 1, characterized in that: First add 46.4 - 49.8 parts of the tetrahydrofuran, 8.7 - 10.3 parts of the diacetone alcohol, and 35.7 - 38.1 parts of the n-heptane into a reaction vessel and place it on a magnetic stirrer to stir evenly. Then add 0.5 - 0.9 parts of the silane coupling agent N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, 1.5 - 2.5 parts of the polyurethane acrylate, and 2.5 - 3.6 parts of the hydrophilic polymer into the reaction vessel and stir for 3 h until completely dissolved to obtain the surface layer coating solution.

4. A hydrophilic coating groove round hole drainage tube according to claim 1, characterized in that: Both the inner and outer walls of the drainage tube are coated with a hydrophilic coating (12). The drainage tube includes a tube body (1). One side of the tube body (1) is provided with a round-hole section (2). Drainage holes (3) are formed in the round-hole section (2). One side of the round-hole section (2) is provided with a transition section (4). One side of the transition section (4) is provided with a groove section (5). The groove section (5) includes a connecting tube (6). A reinforcing rib (7) is arranged inside the connecting tube (6). A groove (8) is formed on the outer surface of the tube body (1). A developing line (9) is arranged inside the groove (8). Marking points (11) are arranged on the outer surface of the tube body.

5. A hydrophilic coating groove round hole drainage tube and a preparation method thereof according to claim 4, characterized in that: The drainage tube is made of a medical polymer material silicone rubber. The hydrophilic coatings (12) on both the inner and outer walls of the drainage tube are composed of a hydrophilic polymer. The hydrophilic polymer is selected from one or two of polyvinylpyrrolidone and polyacrylamide.

6. The hydrophilic coating groove round hole drainage tube and its preparation method according to claim 4, characterized in that: The drainage holes (3) penetrate through the round-hole section (2), and the drainage holes (3) are intermittently and evenly distributed on the surface of the round-hole section (2).

7. A hydrophilic coating groove round hole drainage tube and its preparation method according to claim 4, characterized in that: Drainage grooves (10) are arranged on both sides of the reinforcing rib (7). The reinforcing rib (7) is in a straight shape, and the reinforcing rib (7) is fixedly connected to the connecting tube (6).

8. A hydrophilic coating groove round hole drainage tube and its preparation method according to claim 4, characterized in that: The reinforcing rib (7) is in a "I" shape, a "trident" shape, or a "cross" shape.

9. A hydrophilic coating groove round hole drainage tube and a preparation method thereof according to claim 4, characterized in that: The groove section (5) is fixedly connected to the transition section (4), the transition section (4) is fixedly connected to the round hole section (2), and the round hole section (2) is fixedly connected to the pipe body (1).

10. A hydrophilic coating groove round hole drainage tube according to claim 4 and a preparation method thereof, characterized in that: The groove (8) extends to the groove section (5), and the developer line (9) is fixedly connected to the groove (8).

Images