Hollow guidewire and method of use thereof

Abstract

The invention discloses a hollow guide wire, which relates to the technical field of medical instruments and comprises a circular-tube-shaped external hollow guide wire, a circular-tube-shaped internal hollow guide wire, a mandrel and an air bag system, the internal hollow guide wire is fixed in the tubular interior of the external hollow guide wire through threads; the mandrel is detachably arranged in the tubular interior of the internal hollow guide wire; the shaft outer wall of the mandrel is attached to the inner wall of the internal hollow guide wire; the external hollow guide wire, the internal hollow guide wire and the mandrel are coaxial; the air bag system comprises an annular air bag; the air bag can be expanded and shrunk; an air bag is fixed at the tubular end part of the internal hollow guide wire; the air bag distribution centroid is located on the axis of the mandrel. The circular tube length of the external hollow guide wire is larger than that of the internal hollow guide wire, and the circular tube length of the internal hollow guide wire is larger than that of the mandrel. According to the hollow guide wire provided by the invention, the problems of tedious operation and long time of a neural interventional therapy operation in the prior art are solved, the operation steps of the neural interventional therapy can be optimized, and the operation time is shortened.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a hollow guide wire and its usage method. Background Art

[0002] In neurointerventional therapy, the treatment of chronic total occlusion (CTO) lesions is a highly challenging operation, and the main problems faced by clinicians are the complexity of the operation and the long operation time. At present, the 0.035" guide wire is widely used in the treatment of slow occlusion because it can quickly pass through the thrombotic organization segment, but it has many obvious defects, seriously affecting the surgical efficiency and safety.

[0003] For long-segment occluded blood vessels, clinicians often use a 0.035" guide wire for superselection until the distal true lumen is reached. However, after reaching the true lumen, the subsequent operations are cumbersome and risky. The doctor must first withdraw the angiography guide wire and then re-use a micro-guide wire or micro-catheter for further superselection. This series of operations not only significantly increases the surgical steps and prolongs the operation time, exposing the patient to a longer surgical risk, but also significantly increases the possibility of entering the false lumen. Once entering the false lumen, the subsequent operations will be more complex and may even lead to surgical failure.

[0004] In terms of the performance of the guide wire itself, the 0.035" guide wire has a large effective payload at the tip and cannot enter the intracranial blood vessels for further superselection, greatly limiting its application in the treatment of intracranial lesions. At the same time, its outer diameter is relatively large, and when passing through a narrow blood vessel segment, the puncture is difficult, and the risk of blood vessel rupture or guide wire jamming increases significantly, posing a great obstacle to the smooth progress of the operation.

[0005] In terms of device adaptation, the 0.035" guide wire has poor adaptability to the thinner 0.014" micro-guide wire or 0.017" micro-catheter. When it is necessary to switch to these thinner devices, it is often necessary to replace the guide wire and catheter multiple times, which not only increases the complexity and time cost of the operation, but also may lead to the loss of the established blood vessel lumen. Once the lumen is lost, it is difficult and time-consuming to re-establish the access, further increasing the surgical difficulty and risk.

[0006] In addition, during the process of withdrawing the angiography guide wire and re-using the micro-guide wire and micro-catheter, due to the too thin diameter of the micro-guide wire and micro-catheter, they are extremely easily blocked by the thrombus in the blood vessel. This not only affects the normal use of the micro-guide wire and micro-catheter, but also may cause serious complications such as thrombus displacement and blood vessel blockage during the operation, posing a great risk to the operation.

[0007] In summary, the existing 0.035" guide wire has many problems in neurointerventional therapy, such as cumbersome operation, long time, limited application, high puncture risk, poor adaptability, and susceptibility to thrombus obstruction. Summary of the Invention

[0008] To address the above technical problems, the hollow guide wire provided by the present invention can optimize the operation steps of neurointerventional therapy and reduce the operation time by optimizing the structure of the guide wire. The main purpose of this guide wire is to act as a relay. It can utilize the good shaping ability and tip payload of a 0.035 guide wire to guide a 0.014 micro-guide wire or even a 0.017 micro-catheter to the corresponding position.

[0009] To achieve the above object, the technical solution adopted by the present invention is as follows:

[0010] The hollow guide wire provided by the present invention includes a circular tubular outer hollow guide wire, a circular tubular inner hollow guide wire, a mandrel, and an airbag system; the inner hollow guide wire is detachably fixed inside the tubular inner part of the outer hollow guide wire by a threaded method; the mandrel is detachably arranged inside the tubular inner part of the inner hollow guide wire; the outer wall of the mandrel is closely attached to the inner wall of the inner hollow guide wire; the outer hollow guide wire, the inner hollow guide wire, and the mandrel are all coaxially arranged; the airbag system includes an annular airbag; the airbag can be inflated and deflated; the airbag is fixed at the tubular end of the inner hollow guide wire; the centroid of the airbag distribution is located on the axis of the mandrel; a part of the inner wall of the airbag is attached to the outer wall of the inner hollow guide wire; a part of the inner wall of the airbag extends beyond the end of the inner hollow guide wire; when the airbag is in a deflated state, the inner diameter of the inner wall of the airbag is larger than the circular tube diameter of the inner hollow guide wire; when the airbag is in an inflated state, the inner diameter of the airbag extending beyond the inner circular diameter of the inner hollow guide wire is smaller than the circular tube diameter of the inner hollow guide wire, and the outer diameter of the airbag is larger than the outer diameter of the circular tube of the inner hollow guide wire; the length of the circular tube of the outer hollow guide wire is greater than the length of the circular tube of the inner hollow guide wire, and the length of the circular tube of the inner hollow guide wire is greater than the length of the mandrel.

[0011] Preferably, the detachable fixation by the threaded method for the hollow guide wire provided by the present invention means that: an external thread is provided on the outer wall of the inner hollow guide wire; an internal thread is provided on the inner wall of the outer hollow guide wire; the crest size of the external thread is smaller than the inner diameter of the circular tube of the outer hollow guide wire; the external thread and the internal thread are mutually adapted; after the external thread and the internal thread are threadedly engaged, the inner hollow guide wire is restricted from moving along the axis direction of the circular tube of the outer hollow guide wire by the threaded engagement.

[0012] Preferably, for the hollow guide wire provided by the present invention, the inner diameter of the inner hollow guide wire is uniformly distributed, and the size is 0.008 - 0.035 in, and the outer diameter of the mandrel is 80 - 90% of the inner diameter of the inner hollow guide wire.

[0013] Preferably, the mandrel of the hollow guide wire provided by the present invention is made of stainless steel or made of stainless steel and nitinol alloy.

[0014] For the hollow guide wire provided by the present invention, preferably, the materials of the external hollow guide wire and the internal hollow guide wire are respectively one of polyethylene, stainless steel, nitinol alloy and titanium-nickel alloy.

[0015] For the hollow guide wire provided by the present invention, preferably, the airbag system further includes an airbag adjusting device; the airbag adjusting device includes an expansion unit and a contraction unit; the expansion unit can release an expansion substance into the airbag; the contraction unit can recover the expansion substance from the airbag.

[0016] For the hollow guide wire provided by the present invention, preferably, the expansion substance is one of normal saline and 5%-10% glucose solution.

[0017] For the hollow guide wire provided by the present invention, preferably, a PTFE coating is provided on the inner side of the external hollow guide wire.

[0018] For the hollow guide wire provided by the present invention, preferably, a TPU coating is provided on the outside of the external hollow guide wire, a flat wire layer is provided inside the internal hollow guide wire, the flat wire layer is made by winding flat wires, the material of the flat wires is stainless steel, and the thickness of the flat wire layer is 0.01-0.025 mm.

[0019] For the hollow guide wire provided by the present invention, preferably, the material used for the airbag is one of TPU, nylon and silica gel.

[0020] A method for using a hollow guide wire includes the following steps: S1: Place the hollow guide wire into a blood vessel and reach a designated position, control the airbag to expand, and pull out the mandrel; S2: Insert a replacement material into the hole of the internal hollow guide wire until the replacement material reaches the airbag; S3: Control the airbag to contract, and continue to insert the replacement material provided in step S2 through the annular inner ring of the airbag; S4: Fix the external hollow guide wire, rotate the internal hollow guide wire so that the external hollow guide wire is separated from the internal hollow guide wire, and pull out the internal hollow guide wire.

[0021] The above technical solutions have the following advantages or beneficial effects:

[0022] The present invention discloses a hollow guide wire, which relates to the technical field of medical devices and includes a circular tubular outer hollow guide wire, a circular tubular inner hollow guide wire, a mandrel and an airbag system; the inner hollow guide wire is detachably fixed inside the tubular outer hollow guide wire by means of threads; the mandrel is detachably arranged inside the tubular inner hollow guide wire; the outer wall of the mandrel is closely attached to the inner wall of the inner hollow guide wire; the outer hollow guide wire, the inner hollow guide wire and the mandrel are all arranged coaxially; the airbag system includes an annular airbag; the airbag can be inflated and deflated; the airbag is fixedly attached to the tubular end of the inner hollow guide wire in a sealed and firm manner; the centroid of the distribution of the airbag is located on the axis of the mandrel; the length of the circular tube of the outer hollow guide wire is greater than the length of the circular tube of the inner hollow guide wire, and the length of the circular tube of the inner hollow guide wire is greater than the length of the mandrel; when the airbag is in a deflated state, the annular outer diameter of the airbag is smaller than the inner diameter of the outer hollow guide wire, and the inner hollow guide wire with the deflated airbag can move inside the outer hollow guide wire; when the airbag is in an inflated state, the annular outer wall of the airbag is in contact with the inner wall of the outer hollow guide wire. The hollow guide wire provided by the present invention solves the problems of cumbersome operation and long time in the existing neurointerventional treatment surgery, can optimize the operation steps of neurointerventional treatment, and reduce the operation time. Description of the Drawings

[0023] By reading the detailed description of the non-restrictive embodiments with reference to the following drawings, the present invention and its features, shapes and advantages will become more obvious. The same reference numerals indicate the same parts in all the drawings. The drawings are not deliberately drawn to scale, and the focus is on showing the gist of the present invention.

[0024] Figure 1 It is a three-dimensional sectional view of the hollow guide wire provided in Embodiment 1 of the present invention.

[0025] Figure 2 It is a planar sectional view of the hollow guide wire provided in Embodiment 1 of the present invention.

[0026] Figure 3 It is a side view of the hollow guide wire provided in Embodiment 1 of the present invention. Detailed Description of the Embodiments

[0027] It should be noted that, without conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. It should be noted that the terms used in the present invention are only for describing specific embodiments, and are not intended to limit the exemplary embodiments according to the present application.

[0028] The following will describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments. Therefore, the detailed description of the embodiments of the present invention provided in the following drawings is not intended to limit the scope of the claimed present invention, but only represents the selected embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative efforts belong to the protection scope of the present invention.

[0029] Embodiment 1:

[0030] The hollow guide wire provided in Embodiment 1 of the present invention, as Figures 1 to 3 shown, includes a circular tubular outer hollow guide wire 1, a circular tubular inner hollow guide wire 2, a mandrel 3 and an airbag system 4; the inner hollow guide wire 2 is detachably fixed inside the tubular outer hollow guide wire 1 by a threaded manner; the mandrel 3 is detachably arranged inside the tubular inner hollow guide wire 2; the outer wall of the axis of the mandrel 3 closely abuts against the inner wall of the tube of the inner hollow guide wire 2; the outer hollow guide wire 1, the inner hollow guide wire 2 and the mandrel 3 are all coaxially arranged; the airbag system 4 includes an annular airbag; the airbag can be inflated and deflated; the airbag is fixed at the tubular end of the inner hollow guide wire 2; the centroid of the distribution of the airbag is located on the axis of the mandrel 3; the length of the circular tube of the outer hollow guide wire 1 is greater than the length of the circular tube of the inner hollow guide wire 2, and the length of the circular tube of the inner hollow guide wire 2 is greater than the length of the mandrel 3; when the airbag is in a deflated state, the annular outer diameter of the airbag is smaller than the inner diameter of the outer hollow guide wire 1, and the inner hollow guide wire 2 with the deflated airbag can move inside the outer hollow guide wire 1; when the airbag is in an inflated state, the annular outer wall of the airbag abuts against the inner wall of the outer hollow guide wire 1.

[0031] Specifically, when in use, it is according to the following steps:

[0032] S1: Place the hollow guide wire into the blood vessel and reach the designated position, control the airbag to inflate, and pull out the mandrel.

[0033] S2: Insert the replacement material through the hole of the inner hollow guide wire until the replacement material reaches the airbag.

[0034] S3: Control the airbag to deflate, and continue to insert the replacement material provided in Step S2 through the annular inner ring of the airbag.

[0035] S4: Fix the outer hollow guide wire, rotate the inner hollow guide wire so that the outer hollow guide wire is separated from the inner hollow guide wire, and pull out the inner hollow guide wire.

[0036] The differences from the prior art are as follows: Compared with conventional hollow guidewires, in this embodiment, the internal hollow guidewire 2, the mandrel 3, and the balloon system 4 are added. The inner diameter of a conventional hollow guidewire is relatively fixed and limited in size. In complex surgeries such as neurointervention, there are various types of instruments to be inserted, with different sizes. When the diameter of the instrument to be inserted does not match the inner diameter of the hollow guidewire, the hollow guidewire inserted into the blood vessel needs to be frequently replaced. For some instruments to be inserted, such as microcatheters, although their diameters may theoretically conform to the size of the guidewire's hollow channel, due to the certain flexibility of the instrument itself, it is prone to bending and jamming when passing through the guidewire channel and is difficult to reach the target position smoothly. However, the structure of this embodiment has a balloon system 4, which is fixed to the internal hollow guidewire 2 by plasma welding to assist the internal hollow guidewire 2 in centering within the external hollow guidewire 1. After the external hollow guidewire 1 is sent into the human body at one time, replacement materials can be directly inserted through the internal hollow guidewire 2, reducing the instrument replacement steps and thus saving surgical time. The 0.035" guidewire has a large tip load and a large outer diameter, making it prone to puncture difficulties when passing through narrow blood vessel segments, increasing the risk of blood vessel rupture or guidewire jamming, and it is difficult to enter the intracranial superselection. In the embodiment of the present invention, the mandrel is provided to enhance the guidewire support, and the balloon is provided to block blood clots. In addition, the internal hollow guidewire 2 is detachably fixed to the tubular interior of the external hollow guidewire 1 by a threaded manner. This detachable design enables the current internal hollow guidewire 2 to be conveniently removed and replaced with an internal hollow guidewire 2 adapted to a specific instrument when different instruments need to be delivered. For example, when a microcatheter with a relatively small diameter needs to be delivered, an internal hollow guidewire 2 with a smaller inner diameter and a thicker tube wall to ensure strength can be used; while when a larger-diameter embolization material needs to be delivered, an internal hollow guidewire 2 with a larger inner diameter can be replaced.

[0037] The threaded connection is for providing a stable detachable connection. Compared with other detachable connection methods, the threaded connection has the functions of simplicity and centering. It can continue to rotate to connect or loosen the external hollow guidewire 1 and the internal hollow guidewire 2. The threaded connection between the external hollow guidewire 1 and the internal hollow guidewire 2 can maintain centering according to the engagement between the threads and maintain the positional relationship between the external hollow guidewire 1 and the internal hollow guidewire 2.

[0038] The distance dimension between the thread on the inner hollow guide wire 2 and the port of the outer hollow guide wire 1 is smaller than the distance dimension between the balloon and the port of the outer hollow guide wire 1. When the inner hollow guide wire 2 is connected to the outer hollow guide wire 1 through the thread, ensuring that the threaded part is located in front of the balloon can make the connection point closer to the front end of the guide wire, thereby enhancing the stability of the connection. This design helps prevent the overall performance and accuracy of the guide wire from being affected due to loosening or displacement at the connection when the balloon expands or contracts. Setting the balloon behind the thread can ensure that the balloon will not be interfered by the threaded connection when it expands. In this way, the balloon can expand more freely to achieve the expected blocking effect.

[0039] The mandrel 3 is in contact connection with the inner hollow guide wire 2, and the outer hollow guide wire 1, the inner hollow guide wire 2, and the mandrel 3 are all coaxially arranged. The centroid of the balloon distribution is located on the axis of the outer hollow guide wire 1, the inner hollow guide wire 2, and the mandrel 3. The length dimension of the outer hollow guide wire 1 is greater than the dimension length of the inner hollow guide wire 2, and the length dimension of the inner hollow is greater than the length dimension of the mandrel 3.

[0040] Since the centroid of the balloon distribution is located on the axis of the outer hollow guide wire 1, the inner hollow guide wire 2, and the mandrel 3, this coaxial arrangement can ensure the precise positioning of the balloon in the blood vessel, thereby more effectively controlling the blocking effect of the balloon on the thrombus.

[0041] The length of the outer hollow guide wire 1 is greater than that of the inner hollow guide wire 2, and the length of the inner hollow guide wire 2 is greater than that of the mandrel 3. Such a length configuration can provide better operation flexibility and the ability to adapt to different blood vessel lengths, which helps the guide wire pass smoothly through the blood vessel and reach the target position, reducing the blockage caused by thrombus detachment.

[0042] The inner diameter of the inner hollow guide wire 2 is evenly distributed, and the size is 0.008 - 0.035 in. The outer diameter dimension of the mandrel 3 is 80 - 90% of the inner diameter dimension of the inner hollow guide wire 2. The uniform distribution of the inner diameter of the inner hollow guide wire 2 and the precise size range can ensure the adaptability of the guide wire in the blood vessel, enabling it to adapt to blood vessels of different diameters while maintaining sufficient flexibility and tracking ability to pass through the blood vessel and reach the target position smoothly.

[0043] The contact connection between the mandrel 3 and the inner hollow guide wire 2 and their coaxial arrangement can improve the pushing performance and torsional controllability of the guide wire, making the operation more precise and controllable, which is crucial for preventing thrombus detachment and blockage.

[0044] The material of the mandrel 3 is stainless steel or one of stainless steel and nickel-titanium alloy. The presence of the mandrel 3 provides additional support, making the guide wire more stable in the blood vessel, reducing the displacement or deformation of the guide wire caused by the thrombus shedding, thereby reducing the risk of blockage caused by the thrombus shedding. Nickel-titanium alloy has good shape memory properties and superelasticity, so that the mandrel 3 can maintain flexibility when passing through complex paths in the blood vessel, is not easy to damage the blood vessel wall, and can restore to its original state after bending. The stainless steel material has strong hardness, and the guide wire made has good support force, pushability and torque transmission performance. This characteristic makes the mandrel 3 more effective when pushing the guide wire that has penetrated into the blood vessel in vitro, and it is also convenient to realize in vitro control and torsion operation. The guide wire made of nickel-titanium alloy has good anti-winding ability, which helps to reduce the mutual entanglement of the guide wire during use and improve the safety and efficiency of the operation. By combining the advantages of stainless steel and nickel-titanium alloy, the mandrel 3 can maintain sufficient hardness and pushability while also having good flexibility and intravascular tracking, which helps to improve the success rate of the operation.

[0045] The mandrel 3 plays a key supporting role in the hollow guidewire. It ensures that the internal hollow guidewire 2 maintains a stable shape and structure during use, especially when the balloon is inflated, the presence of the mandrel 3 can prevent the internal hollow guidewire 2 from being deformed or damaged by the pressure of the balloon. This stability is crucial to ensure that the guidewire can accurately reach the specified position. The tight structure formed between the mandrel 3 and the internal hollow guidewire 2 allows for more precise control. During the balloon expansion and contraction process, the presence of the mandrel 3 makes the operation more stable. The use of the mandrel 3 can make the balloon in a contracted state during the insertion process, and the hardness of the mandrel 3 is used for support, which can avoid the swing problem caused by the balloon expansion blocking the insertion process, thereby maintaining the controllability of the guidewire.

[0046] The materials of the outer hollow guide wire 1 and the inner hollow guide wire 2 are respectively one of polyethylene, stainless steel, nickel-titanium alloy and titanium-nickel alloy. Nickel-titanium alloy has unique shape memory, superelasticity, good mechanical properties, friction resistance, corrosion resistance and biocompatibility, which makes nickel-titanium alloy an ideal material for guide wires and reduces the risk of thrombosis. Polyethylene material provides good flexibility and chemical corrosion resistance, which helps to push and position the guide wire in the blood vessel, reduce the operation time and operation complexity, and reduce the risk of thrombus detachment.

[0047] The balloon regulating device includes an inflation unit and a deflation unit. The inflation unit is used to release an inflation substance into the balloon, and the deflation unit recovers the inflation substance from the balloon. By releasing the inflation substance into the balloon through the inflation unit and recovering the inflation substance from the balloon through the deflation unit, the inflation and deflation states of the balloon can be precisely controlled. This precise control helps to effectively manage blood clots at different stages, such as inflating the balloon to fix the position of the guide wire or block blood clots when needed, and deflating the balloon after the operation to facilitate the removal of the guide wire. During interventional surgery, the inflation of the balloon can act as a physical barrier to prevent dislodged blood clots from shifting with the blood flow and reduce the risk of thromboembolism.

[0048] The inflation substance is one of normal saline and a 5%-10% glucose solution. Both normal saline and the 5%-10% glucose solution can be used as inflation substances to inflate the balloon, enabling the balloon to expand. Normal saline and the 5%-10% glucose solution can be present in the blood in appropriate amounts, avoiding harm to the patient's life safety due to the leakage of the inflation substance.

[0049] A PTFE coating is provided inside the outer hollow guide wire 1. The PTFE coating has excellent non-adhesiveness and wear resistance, which can reduce the friction force between the guide wire and the vascular intima. This low friction performance helps the guide wire to pass more easily through the blood vessel and reduces damage to the blood vessel wall. The PTFE coating has good biocompatibility and can reduce irritation and damage to the inner wall of the blood vessel.

[0050] A TPU coating is provided outside the outer hollow guide wire 1, and a flat wire layer is provided inside the inner hollow guide wire 2. The flat wire layer is made by winding flat wires, the material of the flat wires is stainless steel, and the thickness of the flat wire layer is 0.01 - 0.025 mm. The TPU coating has good lubricity, which can reduce the friction force when the guide wire moves in the blood vessel and improve the passability of the guide wire. The flat wire layer provided inside the inner hollow guide wire 2 is made of stainless steel, which can improve the supporting force and tracking performance of the guide wire. The strength and hardness of the stainless steel flat wires contribute to the stable operation of the guide wire in the blood vessel. The anti-thrombogenic property on the surface of the guide wire is crucial for preventing the formation and embolism of blood clots. The combined use of the TPU coating and the stainless steel flat wire layer can inhibit platelet adhesion and thrombus formation, ensuring the smooth operation of the guide wire.

[0051] The material used for the balloon is one of TPU, nylon, and silicone. The antibacterial and waterproof properties of the TPU balloon facilitate the cleaning and disinfection of medical balloons. The silicone balloon, due to its softness and elasticity, can reduce the interference of the catheter on blood flow, thereby reducing the risk of thrombus complications. TPU, silicone, and nylon also have good biocompatibility and are widely used in the medical field.

[0052] To achieve the above object, the second technical solution adopted by the present invention is: a method for using a hollow guide wire, comprising the following steps:

[0053] S1: Place the hollow guide wire into the blood vessel and reach the designated position. Expand the balloon through the balloon adjustment device and pull out the mandrel 3. After reaching the designated position, a physical barrier can be immediately formed in the blood vessel through the expansion of the balloon, preventing the further movement of the detached thrombus and reducing the risk of thrombus spreading with the blood flow. At the same time, pulling out the mandrel 3 prepares for the next operation.

[0054] The balloon adjustment device in the embodiment of the present invention can adopt the balloon adjustment device of a health care or medical surgical device disclosed in Chinese Patent Application No. 202022804846.4. The preferred balloon adjustment device in this embodiment is a balloon adjustment device with remote control. The balloon adjustment device is fixed on the outer wall of the inner hollow guide wire, and its own structure does not affect the passing of the inner hollow guide wire 2 through the outer hollow guide wire 1. The balloon adjustment device has a power supply, a remote control chip, and a liquid injection pump. The expansion unit and the contraction unit respectively control the injection and extraction of the liquid injection pump. Medical staff can control the expansion unit and the contraction unit to work through the remote control chip to realize the work of injecting and extracting liquid into the balloon.

[0055] S2: Insert the replacement material into the hole of the inner hollow guide wire 2 until the replacement material reaches the balloon. The replacement material is directly delivered to the balloon position through the inner hollow guide wire 2. This can ensure that the treatment material acts precisely on the target area, improve the use effect, and reduce the impact on the surrounding healthy blood vessels at the same time. The replacement materials in this application are thrombolytic drugs, embolization materials, stents, coils, etc., preferably 0.014" micro guide wire, 0.018" micro guide wire, and 0.017" micro catheter.

[0056] S3: Make the balloon shrink through the balloon adjustment device, and continue to insert the replacement material until the replacement material exceeds the balloon. The setting of the annular balloon enables the balloon to switch between two states of blockage and dredging through the expansion and contraction of the balloon, so that the balloon can block the contact between the thrombus and the replacement material in the blocked state and reduce the obstruction of the thrombus. Shrinking the balloon can create space for the further insertion of the replacement material, ensuring that the replacement material can smoothly pass through the balloon position and continue to advance forward until it exceeds the balloon. In the dredging state, the hole in the center of the annular balloon can be opened, enabling the replacement material to pass through it, preparing for the subsequent pulling out of the inner hollow guide wire 2.

[0057] S4: Fix the external hollow guide wire 1, rotate the internal hollow guide wire 2 to disengage the external hollow guide wire 1 from the internal hollow guide wire 2, and then pull out the internal hollow guide wire 2. After the delivery of the replacement material is completed, by rotating and pulling out the internal hollow guide wire 2, the guide wire can be safely removed while keeping the external hollow guide wire 1 fixed, which can ensure the stability of the replacement material in the blood vessel.

[0058] During the process of pulling out the mandrel 3, the annular structure of the balloon can be made tighter under the action of atmospheric pressure, thus ensuring the sealing of the internal hollow guide wire 2, and providing a good environment for the subsequent placement of the replacement substance, enabling the replacement substance to be smoothly placed into the blood vessel.

[0059] During the process of pulling out the mandrel 3, reduce the pressure of the balloon. During the process of placing the replacement material, increase the pressure of the balloon. Reducing the pressure of the balloon when pulling out the mandrel 3 can reduce the binding force of the balloon on the mandrel 3, enabling the mandrel 3 to be pulled out more smoothly from the internal hollow guide wire. This helps to avoid excessive resistance during the pulling out process of the mandrel 3, thus preventing its damage or deformation. Increasing the pressure of the balloon when placing the replacement material can ensure that the replacement material is sufficiently supported and fixed when passing through the balloon. This helps to prevent the replacement material from being disturbed by the external environment during the passing process, such as being washed back or disrupted by blood, thus protecting its integrity and function.

[0060] Through the expansion unit and the contraction unit in the balloon adjustment device, the expansion and contraction speeds of the balloon can be precisely controlled, and the insertion speed of the replacement material can be coordinated. By precisely controlling the contraction speed of the balloon and the insertion speed of the replacement material, it can be ensured that the replacement material will not be washed back or disrupted by the inflowing blood during the contraction process of the balloon. By precisely controlling the movement of the balloon and the replacement material, more accurate positioning and operation can be achieved, thereby improving the accuracy of the operation.

[0061] The winding of the flat wire can provide additional stability and support for the internal hollow guide wire 2. The winding of the flat wire can also play a certain protective role for the mandrel 3, reducing the direct friction between the mandrel 3 and the inner wall of the guide wire during the pulling out process, thereby reducing the risk of wear of the mandrel 3. The flat wire is wound on the inner wall of the guide wire, which can form a certain guiding channel. This helps to make it easier for the replacement material to enter the target position along the predetermined path when it is placed. The softness and elasticity of the flat wire help to reduce the damage to the internal hollow guide wire 2 and the mandrel 3 inside the guide wire during the placement process of the replacement material. This can not only extend the service life of the internal hollow guide wire 2 and the mandrel 3, but also reduce the risks during the operation or procedure.

[0062] Both the openings of the external hollow guide wire 1 and the internal hollow guide wire 2 are rounded. The rounding treatment can reduce the stress concentration at the opening of the guide wire, avoiding fracture or damage due to excessive force during use. This design helps to extend the service life of the guide wire and improve the reliability and safety of the operation. The rounding treatment makes the opening of the guide wire smoother, reducing the friction with the blood vessel wall or other medical devices. This helps the guide wire to move more smoothly in the blood vessel, reducing the resistance and discomfort during the operation.

[0063] After the hollow guide wire is used up, first pull out the entire hollow guide wire. When the replacement materials include materials that need to be taken out, such as micro guide wires or micro catheters, the replacement materials need to be additionally pulled out from the hollow guide wire.

[0064] Embodiment 2

[0065] This embodiment provides a hollow guide wire, including: an external hollow guide wire 1, an internal hollow guide wire 2 disposed inside the external hollow guide wire 1, and a mandrel 3 disposed inside the internal hollow guide wire 2.

[0066] The connection between the external hollow guide wire 1 and the internal hollow guide wire 2 is a threaded connection. An airbag system 4 is provided at one end of the internal hollow guide wire 2. The airbag system 4 includes an airbag and an airbag adjusting device. The airbag adjusting device is used to control the inflation and deflation of the airbag. The airbag is an annular airbag. The thread on the internal hollow guide wire 2 and the airbag are located at the same end.

[0067] The mandrel 3 is in contact connection with the internal hollow guide wire 2. The external hollow guide wire 1, the internal hollow guide wire 2, and the mandrel 3 are all coaxially arranged. The centroid of the airbag distribution is located on the axis of the external hollow guide wire 1, the internal hollow guide wire 2, and the mandrel 3. The length dimension of the external hollow guide wire 1 is greater than the dimension length of the internal hollow guide wire 2, and the length dimension of the internal hollow dimension is greater than the length dimension of the mandrel 3.

[0068] The inner diameter of the internal hollow guide wire 2 is evenly distributed and has a size of 0.02 in. The outer diameter size of the mandrel 3 is 0.017 in.

[0069] The material of the mandrel 3 is stainless steel, the material of the external hollow guide wire 1 is polyethylene, and the material of the internal hollow guide wire 2 is polyethylene.

[0070] The airbag adjusting device includes an inflation unit and a deflation unit. The inflation unit is used to release the inflation substance into the airbag, and the deflation unit recovers the inflation substance from the airbag. The inflation substance is normal saline.

[0071] A PTFE coating is provided on the inner side of the external hollow guide wire 1.

[0072] The outer hollow guide wire 1 is externally provided with a TPU coating, and the inner hollow guide wire 2 is internally provided with a flat wire layer. The flat wire layer is made by winding flat wires. The flat wire is made of stainless steel, and the thickness of the flat wire layer is 0.025 mm.

[0073] In summary, the present invention discloses a hollow guide wire, which relates to the technical field of medical devices and includes a circular tubular outer hollow guide wire, a circular tubular inner hollow guide wire, a mandrel and an airbag system; the inner hollow guide wire is detachably fixed in the tubular interior of the outer hollow guide wire by a threaded manner; the mandrel is detachably arranged in the tubular interior of the inner hollow guide wire; the outer wall of the mandrel is closely attached to the inner wall of the inner hollow guide wire; the outer hollow guide wire, the inner hollow guide wire and the mandrel are all coaxially arranged; the airbag system includes an annular airbag; the airbag can be inflated and deflated; the tubular end of the inner hollow guide wire is fixedly provided with the airbag in a sealed and firm manner; the centroid of the distribution of the airbag is located on the axis of the mandrel; the length of the circular tube of the outer hollow guide wire is greater than the length of the circular tube of the inner hollow guide wire, and the length of the circular tube of the inner hollow guide wire is greater than the length of the mandrel; when the airbag is in a deflated state, the annular outer diameter of the airbag is smaller than the inner diameter of the outer hollow guide wire, and the inner hollow guide wire with the deflated airbag can move within the outer hollow guide wire; when the airbag is in an inflated state, the annular outer wall of the airbag is in contact with the inner wall of the outer hollow guide wire. The hollow guide wire provided by the present invention solves the problems of cumbersome operation and long time in the existing neurointerventional treatment surgery, can optimize the operation steps of neurointerventional treatment, and reduce the operation time.

[0074] The above are only the preferred embodiments of the present invention, and do not limit the patent scope of the present invention. Any equivalent structural transformation made by using the content of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, shall be included in the patent protection scope of the present invention by the same token.

Claims

1. A hollow guide wire, characterized in that, It includes a circular tubular outer hollow guide wire, a circular tubular inner hollow guide wire, a mandrel and an airbag system; The inner hollow guide wire is detachably fixed inside the tubular interior of the outer hollow guide wire by means of threads; The mandrel is detachably arranged inside the tubular interior of the inner hollow guide wire; The outer wall of the mandrel closely abuts against the inner wall of the inner hollow guide wire; The outer hollow guide wire, the inner hollow guide wire and the mandrel are all coaxially arranged; The airbag system includes an annular airbag; the airbag can be inflated and deflated; The airbag is fixed to the tubular end of the inner hollow guide wire; The centroid of the distribution of the airbag is located on the axis of the mandrel; a part of the inner wall of the airbag abuts against the outer wall of the inner hollow guide wire; a part of the inner wall of the airbag extends beyond the end of the inner hollow guide wire; When the airbag is in the deflated state, the inner diameter of the inner wall of the airbag is larger than the circular tube diameter of the inner hollow guide wire; When the airbag is in the inflated state, the inner diameter of the airbag extending beyond the inner circular diameter of the inner hollow guide wire is smaller than the circular tube diameter of the inner hollow guide wire, and the outer circular diameter of the airbag is larger than the outer diameter dimension of the circular tube of the inner hollow guide wire; The length of the circular tube of the outer hollow guide wire is greater than the length of the circular tube of the inner hollow guide wire, and the length of the circular tube of the inner hollow guide wire is greater than the length of the mandrel.

2. The hollow guide wire according to claim 1, characterized in that, Detachable fixation by means of threads means that: an external thread is provided on the outer wall of the inner hollow guide wire; an internal thread is provided on the inner wall of the outer hollow guide wire; the crest dimension of the external thread is smaller than the inner diameter dimension of the circular tube of the outer hollow guide wire; the external thread and the internal thread are mutually adapted; after the external thread and the internal thread are thread - mated, the inner hollow guide wire is restricted from moving along the axis direction of the circular tube of the outer hollow guide wire by the thread - mating.

3. The hollow guide wire according to claim 1, characterized in that, The inner diameter of the inner hollow guide wire is uniformly distributed; the inner diameter dimension of the inner hollow guide wire is 0.008 - 0.035 in; the outer diameter dimension of the mandrel is 80 - 90% of the inner diameter dimension of the inner hollow guide wire.

4. The hollow guide wire according to claim 1, wherein, The mandrel is made of stainless steel or made of stainless steel and nitinol alloy.

5. The hollow guide wire according to claim 1, characterized in that, The materials of the outer hollow guide wire and the inner hollow guide wire are respectively one of polyethylene, stainless steel, nitinol alloy and titanium - nickel alloy.

6. The hollow guide wire according to claim 1, characterized in that, The airbag system further includes an airbag adjusting device; the airbag adjusting device is fixed to the outer wall of the inner hollow guide wire; the airbag adjusting device includes an inflation unit and a deflation unit; the inflation unit can release an inflation substance into the airbag; the deflation unit can recover the inflation substance from the airbag.

7. The hollow guide wire according to claim 6, characterized in that, The inflation substance is one of physiological saline and a 5% - 10% glucose solution.

8. The hollow guide wire according to claim 1, characterized in that, A PTFE coating is provided on the inner side of the outer hollow guide wire.

9. The hollow guide wire according to claim 1, wherein, A TPU coating is provided on the outside of the outer hollow guide wire; a flat wire layer is provided inside the inner hollow guide wire; the flat wire layer is made by winding flat wires; the material of the flat wire is stainless steel; the thickness of the flat wire layer is 0.01 - 0.025 mm.

10. A hollow guide wire according to claim 1, characterized in that, The material used for the airbag is one of TPU, nylon and silica gel.

11. A method for using a hollow guide wire, based on a hollow guide wire according to any one of claims 1-10, characterized in that, It includes the following steps: S1: Place the hollow guide wire into the blood vessel and reach the designated position, control the balloon to expand, and pull out the mandrel; S2: Insert the replacement material through the hole of the inner hollow guide wire until the replacement material reaches the balloon; S3: Control the balloon to shrink, and continue to insert the replacement material provided in step S2 through the annular inner ring of the balloon; S4: Fix the outer hollow guide wire, rotate the inner hollow guide wire so that the outer hollow guide wire is separated from the inner hollow guide wire, and pull out the inner hollow guide wire.

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