Facial cleansing composition with deep penetration-cleaning synergistic effect as well as preparation method and application of facial cleansing composition

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a face cleaning composition with a deep penetration-cleaning synergistic effect and a preparation method and application thereof.The face cleaning composition comprises a cleaning phase D and an effect phase F, and the cleaning phase D and the effect phase F jointly construct a deep penetration-cleaning synergistic mechanism; the cleaning component of the cleaning phase D comprises candida albicans / glucose / rapeseed methyl oleate fermentation products; the functional F phase is a composite plant extract and comprises a papaya extract, salvia miltiorrhiza root powder, angelica sinensis root powder, houttuynia cordata powder, scutellaria baicalensis root powder and a honeysuckle flower extract. According to the composition, a deep penetration-cleaning synergistic mechanism is jointly constructed through the synergistic effect of the cleaning phase D and the effect phase F, the synergistic effect of deep penetration of cleaning and skin care active ingredients can be achieved on the basis that the efficient and mild cleaning effect is guaranteed, and the skin barrier is repaired and enhanced.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and specifically relates to a cosmetic composition for skin cleansing, and more particularly to a facial cleansing composition with deep penetration-cleansing synergistic effects, and a preparation method and application thereof. Background Art

[0002] The skin is the body's largest organ, and its outermost layer, the stratum corneum, forms a core barrier against physical, chemical, and biological damage. Daily cleansing is a fundamental step in skincare, aiming to remove excess sebum, metabolic waste, makeup residue, and environmental pollutants (such as PM2.5 particles) from the skin's surface.

[0003] Existing facial cleansers face two major technical challenges. First, the conflict between cleansing power and mildness. Traditional facial cleansers rely heavily on powerful anionic surfactants, such as sodium laureth sulfate (SLES). While these surfactants offer strong cleansing power, they work by emulsifying and removing oil from the skin's surface. This process often excessively removes intercellular lipids, which are crucial for barrier function, and can lead to denaturation of stratum corneum proteins. Long-term use can lead to dryness, tightness, sensitivity, and even barrier damage. In pursuit of mildness, many products have turned to amino acid surfactants or amphoteric surfactants, but these often exhibit reduced cleansing power, particularly for waterproof makeup and stubborn dirt.

[0004] Second, there's the "wash-off dilemma" of active ingredients. Facial cleansers, as rinse-off products, have a very short duration of action on the skin, typically less than a minute. This makes it extremely difficult for various skincare active ingredients (such as moisturizers, soothing agents, and antioxidants) added to the formula to penetrate the skin and take effect. Most of these active ingredients are washed away during the rinsing process and are not truly utilized by the skin. This waste also limits the functionality of facial cleansers. While existing technologies have attempted to deliver active ingredients to the skin by increasing the concentration of active ingredients or using basic penetration enhancers, these efforts have been limited. High concentrations of active ingredients in facial cleansers can also increase the risk of skin irritation. Furthermore, while facial cleansers cleanse facial dirt, especially to achieve oil control, they also inevitably remove a significant amount of facial oil, leading to dryness and tightness. Therefore, developing a facial cleanser that is both gentle and effective, while also providing functionality, is a constant pursuit within the industry.

[0005] Chinese patent document CN117815158A discloses a repairing and whitening composition and its preparation method. The composition comprises, by mass percentage, the following: Phase A: humectant A, stabilizer, antioxidant A, and water; Phase B: thickener A and humectant B; Phase C: skin conditioner A; Phase D: emollient, Candida albiflora / glucose / rapeseed oleate fermentation product, avocado butter, and dimethylmethoxychromanol; Phase E: skin conditioner B, thickener B, and antioxidant B; and Phase F: hydrolyzed rice protein, chlorella extract, plum blossom extract, yeast lysate extract, baobab seed extract, leontopodium alpinum callus extract, and hops extract. This technical solution can effectively reduce the amount of active ingredients used while providing improved whitening, repairing, and moisturizing benefits. However, it lacks gentle and effective cleansing properties.

[0006] Chinese patent document CN118490595A discloses a composition with oil-control and moisturizing properties and its use. The composition comprises a first active ingredient, capryloylglycine, and a fermentation product of Candida mellifera, glucose, and rapeseed methyl ester; the first active ingredient comprises Centella asiatica extract, madecassoside, and glucose. While this technical solution can remove oil and provide good moisturizing properties, the moisturizing effect is only temporary on the skin's surface and fails to penetrate deeper into the skin's layers.

[0007] Therefore, how to break through the limitations of existing technologies and develop a new cleansing composition that can overcome the "wash-off dilemma" while ensuring efficient and gentle cleansing, achieve the synergistic effect of deep penetration of cleansing and skin care active ingredients, and thus provide additional health benefits to the skin while cleansing, is a technical problem that needs to be urgently solved in this field. Summary of the Invention

[0008] The purpose of the present invention is to provide a cleansing composition with synergistic effects of deep penetration and efficient cleaning, as well as its preparation method and application, to alleviate the above-mentioned shortcomings in the prior art. On the basis of taking into account the high efficiency and mild cleaning effects, it realizes the deep penetration of skin care active ingredients, and ultimately enhances the skin barrier based on the synergistic effect of deep penetration and effective cleaning.

[0009] In order to solve the above-mentioned technical problems, the present invention specifically adopts the following technical solutions: A first aspect of the present invention is to provide a facial cleansing composition with a deep penetration-cleansing synergistic effect, the composition comprising a cleansing phase D and a functional phase F, which together construct a deep penetration-cleansing synergistic mechanism; the cleansing phase D comprises a biosurfactant and an emollient; the biosurfactant is a fermentation product of Candida albicans / glucose / rapeseed oleic acid methyl ester; the synergistic phase F is a composite plant extract, comprising carica papaya (Carica papaya) extract, salvia miltiorrhiza (Salvia miltiorrhiza) root powder, angelica sinensis (Angelica sinensis) root powder, houttuynia cordata (Houttuynia cordata) powder, scutellaria baicalensis (Scutellaria baicalensis) root powder, and honeysuckle (Lonicera japonica) flower extract.

[0010] Using the above technical solution, first of all, in terms of the cleansing mechanism, the present invention abandons traditional highly irritating surfactants and innovatively adopts the fermentation product of Candida albicans / glucose / rapeseed oleate as the core cleansing ingredient. This is a biologically derived surfactant belonging to the sophorolipid family, and its molecular structure enables it to form micelles that are very gentle on the skin's lipid structure. It can effectively encapsulate and remove sebum and dirt, while also having its own biological activity to protect the skin and regulate sebum secretion, thus avoiding damage to the skin barrier during the cleansing process at the source.

[0011] At the same time, it is recognized that in skin care, an intact, undamaged skin barrier is more effective in transporting substances than a barrier damaged by chemicals. Therefore, the present invention constructs a "deep penetration-cleansing synergy" mechanism through the synergistic action of the cleansing efficacy phase D and the synergistic efficacy phase F. That is, it utilizes the short process of cleansing massage to create a "transient penetration window" through the synergistic plant extract complex in the synergistic efficacy phase F. The specific mechanism of action is as follows: (1) Opening channels: First, the root powder of Salvia miltiorrhiza (SALVIA MILTIORRHIZA) in the synergistic efficacy phase F has been scientifically proven to effectively stimulate the synthesis of aquaporin-3 (AQP3) in keratinocytes; AQP3 is a key channel in the skin responsible for the transmembrane transport of small molecules such as water and glycerol. During the short period of cleansing and massage, the instantaneous activation of AQP3 provides a "highway" for the rapid penetration of water-soluble active ingredients. At the same time, the root powder extract of Angelica sinensis has been reported to improve the connection and transport between epidermal cells, which may further promote the penetration of active ingredients by regulating tight junction proteins; that is, opening the permeation channel; (2) Nutrient delivery and repair: While the permeation channel is instantaneously opened, other ingredients in the complex are efficiently delivered. Synergistic Efficacy The papaya (CARICA PAPAYA) extract in Phase F is rich in specific polysaccharides and proteins. Studies have shown that it can promote cell migration and skin barrier repair. Houttuynia cordata powder is rich in glycosaminoglycan (GAGs) precursors and minerals, which can provide deep hydration to the skin and support collagen synthesis, instantly replenishing skin moisture and structural support after cleansing; Scutellaria baicalensis root powder, as a powerful antioxidant, can instantly neutralize free radicals caused by pollutants during the cleansing process, protect collagen and elastin from degradation, and play an anti-inflammatory and anti-aging role. (3) Protection after cleansing: Lonicera japonica flower extract is rich in polysaccharides, which can form a breathable, non-occlusive three-dimensional network protective film on the skin surface, reducing water loss after rinsing and giving the skin a smooth and firm feel, avoiding the tightness and discomfort after traditional cleansing; Therefore, by using mild bio-sourced surfactants and specific plant extract complexes to work synergistically, while effectively cleaning skin dirt and makeup, plant extracts are used to promote the instantaneous penetration of active ingredients and repair and nourish the skin barrier, achieving a synergistic effect of deep penetration and efficient cleansing. After use, the skin feels refreshed, hydrated and not tight, and long-term use helps improve skin health.

[0012] Preferably, the mass ratio of the fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester to the efficacy phase F is (1-2): 1. The composite plant extract of the efficacy phase F is prepared in advance as an aqueous premix.

[0013] Preferably, the mass ratio of papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria root powder and honeysuckle extract in the efficacy F phase is (4-6):(4-6):(3-5):(1-3):(1-3):(1-3).

[0014] More preferably, the mass ratio of papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria baicalensis root powder and honeysuckle flower extract is (0.375-0.75):(0.375-0.75):(0.3-0.6):(0.15-0.3):(0.15-0.3):(0.15-0.3).

[0015] Preferably, the composition further comprises a base A phase, a thickening B phase, an efficacy C phase and an efficacy E phase; The base phase A comprises 0.5-5 wt% of a first moisturizing agent, 2-5 wt% of a second moisturizing agent, 0.1-2 wt% of a stabilizer, and the balance is made up of water; The thickening phase B comprises 0.1-2 wt% of a thickener and 2-10 wt% of a third moisturizing agent; The efficacy phase C comprises 0.1-5 wt% of a skin conditioning agent; The efficacy E phase includes 0.1-5 wt% active matter.

[0016] Preferably, the cleansing efficacy D phase further comprises 5-15 wt% of an emollient.

[0017] Preferably, the first moisturizing agent in the base phase A is at least one of sodium polyglutamate, glycosyl trehalose, and erythritol; and the stabilizer is at least one of tetrasodium dicarboxymethylaspartate, sodium phytate, and a dipotassium hydrogen phosphate / potassium dihydrogen phosphate buffer pair.

[0018] Preferably, the first moisturizing agent in the base phase A is sodium polyglutamate; the stabilizer is tetrasodium dicarboxymethylaspartate; and the second moisturizing agent is glycerin.

[0019] Preferably, the thickener in the thickening phase B is polyacrylate crosspolymer-6 and / or ammonium polyacryloyldimethyltaurate; and the third humectant is at least one of butylene glycol, propylene glycol, and pentylene glycol.

[0020] Preferably, the thickener in the thickening phase B is polyacrylate crosspolymer-6; and the third humectant is butylene glycol.

[0021] Preferably, the skin conditioning agent in the efficacy phase C is a nonionic emulsifier, which is polyglyceryl-10 laurate and / or polyglyceryl-3 diisostearate.

[0022] Preferably, the emollient in the cleansing efficacy phase D is selected from at least one of hydrogenated polydidecene, caprylic / capric triglyceride, and jojoba seed oil.

[0023] Preferably, the efficacy phase E comprises active substances with antioxidant efficacy and / or active substances with barrier repair efficacy.

[0024] The second aspect of the present invention is to provide a cleansing composition with deep penetration-cleansing synergistic effect and its use in preparing cleansing products.

[0025] Preferably, the types of the facial cleansing product include oil-in-water emulsion type, gel / gel (emulsion) type, paste or cream type, oil type, powder type or solid soap type.

[0026] The third aspect of the present invention is to provide a novel cleansing product comprising the above-mentioned cleansing composition with deep penetration-cleansing synergistic effect.

[0027] A fourth aspect of the present invention is to provide a method for preparing the novel facial cleanser, comprising the following steps: S1: Mix the components of the base phase A evenly, heat them to 75-85°C to obtain the base phase A, and set aside; mix the components of the cleansing phase D evenly, heat them to 75-85°C to obtain the cleansing phase D, and set aside; S2: Disperse the components of the thickening phase B in the base phase A, use a frame stirrer at a stirring speed of 50-100 rpm, and stir for 15-20 minutes until completely dissolved and uniform to obtain a mixed phase; S3: Under stirring conditions, slowly add the cleansing phase D mixed evenly in the step S1 to the mixed phase obtained in the step S2, and perform high-speed homogenization and emulsification at a speed of 3000-5000 rpm; S4: Turn on the cooling, cool to 55-65°C, add the components of the efficacy phase C and efficacy phase E, and stir evenly; S5: Continue to cool to 40-45°C, add the components of the efficacy phase F, stir evenly, and cool to room temperature to obtain the cleansing composition.

[0028] Preferably, the homogenizing and emulsifying process in step S3 and the cooling and stirring processes in steps S4 and S5 are all performed under a vacuum condition of -0.06 MPa to -0.1 MPa to ensure that the emulsion system is delicate, stable, and free of bubbles.

[0029] Preferably, the homogenization and emulsification time in step S3 is 3-8 minutes.

[0030] Beneficial technical effects: Compared with the prior art, the technical solution of the present invention has the following beneficial technical effects.

[0031] (1) Achieved synergistic effect of cleaning and penetration: The present invention transforms the cleaning process into an efficient active substance introduction process through a specific formula design, overcoming the "washing away dilemma" of the effective ingredients of cleansing products, and achieving the three major effects of cleaning, penetration and repair in just one minute, which is a significant technological advancement.

[0032] (2) Novel formula and distinct technical features: The core ingredients selected by the present invention, such as the fermentation product of Candida albicans / glucose / rapeseed oleic acid methyl ester, and the complex composed of a variety of uncommon plant extracts such as papaya extract and salvia miltiorrhiza root powder, synergistically construct a "deep penetration-cleansing synergy" mechanism. Each component is indispensable and has not been reported in existing cleansing products.

[0033] (3) Mildness and efficacy: This composition provides a cleansing power comparable to traditional products while significantly reducing irritation and damage to the skin barrier. Long-term use will not cause dryness or sensitivity to the skin. Instead, it can continuously introduce repairing ingredients, enhance the skin barrier function, improve skin hydration, and achieve a "healthier with each wash" skin care effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 These are skin test photographs of a volunteer using the product prepared in Specific Test Example 1 of the present invention; (a) is the original photograph of the volunteer's skin condition before using the product of the present invention; (b) is the original photograph of the volunteer's skin condition 14 days after using the product of the present invention; (c) is a photograph of the skin condition as measured by an instrument before using the product of the present invention; and (d) is a photograph of the skin condition as measured by an instrument after using the product of the present invention for 14 days. Figure 2 These are skin test photos of the product prepared by specific Test Example 1 of the present invention used in another volunteer example, wherein (a) is the original photo of the volunteer's skin condition before using the product of the present invention; (b) is the original photo of the skin condition 14 days after using the product of the present invention; (c) is a photo of the skin condition detected by an instrument before using the product of the present invention; and (d) is a photo of the skin condition detected by an instrument 14 days after using the product of the present invention. DETAILED DESCRIPTION

[0035] To make the purpose, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0036] As used herein, "and / or" includes any and all combinations of one or more of the associated listed items.

[0037] Herein, "plurality" means two or more than two, ie, it includes two, three, four, five, etc.

[0038] As used in this specification, the term "about" typically means + / - 5% of the stated value, more typically + / - 4% of the stated value, more typically + / - 3% of the stated value, more typically + / - 2% of the stated value, even more typically + / - 1% of the stated value, and even more typically + / - 0.5% of the stated value.

[0039] In this specification, certain embodiments may be disclosed in a format that is within a range. It should be understood that this description of "within a range" is merely for convenience and brevity and should not be interpreted as a rigid limitation on the disclosed range. Therefore, the description of a range should be considered to have specifically disclosed all possible subranges and individual numerical values ​​within this range. For example, the description of a range of 1-6 should be considered to have specifically disclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., as well as individual numbers within this range, such as 1, 2, 3, 4, 5, and 6. Regardless of the breadth of the range, the above rules apply.

[0040] Definition of noun: The "deep penetration-cleansing synergy" described in the present invention means that after the composition provided by the present invention is prepared into a cleansing product, it can achieve gentle and efficient cleansing of the skin while also allowing the effective ingredients contained in the composition to efficiently penetrate into the skin, thereby improving the skin's barrier function and the absorption effect of the functional ingredients.

[0041] CARICA PAPAYA means papaya; SALVIA MILTIORRHIZA means Salvia miltiorrhiza; ANGELICA SINENSIS means angelica; HOUTTUYNIA CORDATA means houttuynia cordata; SCUTELLARIA BAICALENSIS) means Scutellaria baicalensis; LONICERA JAPONICA means honeysuckle; SIMMONDSIA CHINENSIS means jojoba; SLES stands for traditional surfactant sodium laureth sulfate In the following examples, unless otherwise specified, all raw materials used are commercially available cosmetic grade raw materials, and the mass percentages thereof are based on the total mass of the composition.

[0042] Example 1 Provided is a cleansing composition with a deep penetration-cleansing synergistic effect, the composition comprising a cleansing phase D and an efficacy phase F, wherein the cleansing phase D and the efficacy phase F jointly construct a deep penetration-cleansing synergistic mechanism; the cleansing composition further comprises a base phase A, a thickening phase B, an efficacy phase C, and an efficacy phase E; The base phase A comprises 0.5-5 wt% of a first moisturizing agent, 2-5 wt% of a second moisturizing agent, 0.1-2 wt% of a stabilizer, and the balance is made up of water; The thickening phase B comprises 0.1-2 wt% of a thickener and 2-10 wt% of a third moisturizing agent; The efficacy phase C comprises 0.1-5 wt% of a skin conditioning agent; The cleansing phase D comprises 5-15 wt% of an emollient and 0.5-5 wt% of a biosurfactant; the biosurfactant is a fermentation product of Candida albicans / glucose / rapeseed oleate; The efficacy E phase includes 0.1-5wt% active ingredients; The efficacy F phase comprises 0.1-5 wt% of a composite plant extract, and the synergistic plant extract complex comprises papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria baicalensis root powder and honeysuckle flower extract.

[0043] The mass ratio of the fermentation product of Candida albiflora / glucose / rapeseed methyl ester to the functional F phase is (1-2):1.

[0044] The mass ratio of papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria root powder and honeysuckle extract in the efficacy F phase is (4-6):(4-6):(3-5):(1-3):(1-3):(1-3).

[0045] The first moisturizing agent in the base phase A is at least one of sodium polyglutamate, glycosyl trehalose, and erythritol; the stabilizer is at least one of tetrasodium dicarboxymethylaspartate, sodium phytate, and a dipotassium hydrogen phosphate / potassium dihydrogen phosphate buffer pair.

[0046] The second moisturizing agent is glycerin.

[0047] In some specific embodiments, the first humectant in the base phase A is sodium polyglutamate; the stabilizer is tetrasodium dicarboxymethyl aspartate; and the second humectant is glycerin.

[0048] The thickener in the thickening phase B is polyacrylate crosspolymer-6 and / or ammonium polyacryloyldimethyltaurate; the third moisturizing agent is at least one of butylene glycol, propylene glycol, and pentylene glycol.

[0049] In some specific embodiments, the thickener in the thickening phase B is polyacrylate crosspolymer-6; and the third humectant is butylene glycol.

[0050] The skin conditioning agent in the efficacy phase C is a nonionic emulsifier, specifically polyglyceryl-10 laurate and / or polyglyceryl-3 diisostearate.

[0051] The emollient in the cleansing phase D is selected from at least one of hydrogenated polydidecene, caprylic / capric triglyceride, and jojoba seed oil.

[0052] After being prepared as a cleaning product, the facial cleansing composition with deep penetration-cleansing synergistic effect is in the form of an oil-in-water emulsion or a gel emulsion.

[0053] Definitions, preferred examples and action mechanisms of the components in the cleansing composition with deep penetration-cleansing synergistic effect: (1) Basic phase A: 1) First Moisturizer: Preferably, a mild moisturizer with excellent moisturizing properties is used, such as sodium polyglutamate, glycosyl trehalose, erythritol, etc. In the present invention, sodium polyglutamate is preferred because of its strong water-binding capacity, which can pre-establish a moisturizing foundation in the aqueous phase.

[0054] 2) Stabilizer: This primarily chelates metal ions and regulates pH to maintain system stability. Preferred are skin-friendly chelating agents or buffers, such as tetrasodium dicarboxymethylaspartate, sodium phytate, and a dipotassium hydrogen phosphate / potassium dihydrogen phosphate buffer pair. In this invention, tetrasodium dicarboxymethylaspartate is preferred, as it is a biodegradable, green chelating agent.

[0055] (2) Thickening phase B: 1) Thickener: This is used to build the product's base viscosity and texture. Pre-neutralized, electrolyte-resistant synthetic polymers are preferred, such as polyacrylate crosspolymer-6 and ammonium polyacryloyldimethyltaurate. In this application, polyacrylate crosspolymer-6 is preferred, as it forms a light, non-sticky gel network.

[0056] 2) Third Moisturizing Agent: As a solvent and moisturizing agent, preferably a small molecule polyol, such as butanediol, propylene glycol, pentanediol, etc. Butanediol is preferred in the embodiment of the present invention.

[0057] (3) Efficacy Phase C: Skin Conditioning Agent: This agent primarily assists in emulsification and regulates skin feel. Nonionic emulsifiers are preferred, such as polyglycerol esters, for example, polyglyceryl-10 laurate, polyglyceryl-3 diisostearate, etc.

[0058] (4) Cleaning phase D: 1) Emollients: These provide a lubricating effect during cleansing and help dissolve oil-soluble impurities. Preferred are synthetic esters or hydrocarbons that are light and spreadable, such as caprylic / capric triglyceride, hydrogenated polydidecene, squalane, and jojoba (Simmondsia Chinensis) seed oil.

[0059] 2) Candida albicans / glucose / rapeseed methyl ester fermentation product: The core cleansing and emulsifying ingredient of this invention is a sophorolipid biosurfactant that can replace some traditional emulsifiers. It has multiple functions such as cleansing, emulsification, antibacterial, and oil control, and is extremely gentle on the skin.

[0060] (5) Efficacy phase E: Active ingredients: Additional functional ingredients added as needed, such as antioxidants (such as tocopheryl acetate, ergothioneine), repair ingredients (such as ceramide), etc.

[0061] (6) Efficacy Phase F: Complex plant extracts: The usage information of all extracts contained in Efficacy Phase F can be found in the "Information on the Use of Raw Materials of Cosmetic Products on the Market" to ensure their compliance.

[0062] The synergistic effect of the cleansing phase D and the efficacy phase F is achieved together to achieve a "deep penetration-cleansing synergy" effect; that is, it utilizes the short process of cleansing massage to create an "instantaneous penetration window" through the synergistic plant extract complex in the efficacy phase F; in addition, the synergistic effect of the emollients and biosurfactants in the efficacy phase F achieves a gentle yet highly effective cleansing effect; the mechanism of action is: (1) Efficacy: The various plant extract ingredients in phase F have the ability to open skin channels and effectively stimulate the synthesis of water channel proteins in keratinocytes, thereby enabling a variety of water-soluble active ingredients to penetrate quickly, providing a repairing effect on the skin, and ultimately achieving the effect of improving the skin barrier function.

[0063] (2) Gentle and efficient cleansing: The emollient in the cleansing phase D can help dissolve oil-soluble dirt on the skin surface and assist the fermentation product of Candida albicans / glucose / rapeseed oleate to play an emulsifying and cleansing role.

[0064] In summary, the cleansing composition with deep penetration-cleansing synergistic effect has a prospect of being prepared into a cleansing product.

[0065] In some specific embodiments, the facial cleansing product is in the form of an oil-in-water emulsion, a gel / gel emulsion, a foam, a paste, a cream, an oil, a powder, or a solid soap.

[0066] A method for preparing a facial cleansing product comprising a facial cleansing composition having a deep penetration-cleansing synergistic effect comprises the following steps: S1: Mix the components of the base phase A evenly, heat to 75-85°C, and obtain the base phase A, which is set aside; mix the components of the clean phase D evenly, heat to 75-85°C, and obtain the clean phase D, which is set aside; S2: Disperse the components of the thickening phase B in the base phase A, using a frame stirrer at a stirring speed of 50-100 rpm for 15-20 minutes, and stir until completely dissolved and uniformly dissolved to obtain a mixed phase; S3: Under stirring conditions, slowly add the cleansing phase D mixed uniformly in step S1 to the mixed phase obtained in step S2, and perform high-speed homogenization and emulsification at a speed of 3000-5000 rpm for 3-8 minutes; S4: Turn on the cooling, cool to 55-65°C, add the components of the efficacy phase C and efficacy phase E, and use magnetic stirring at a stirring speed of 50-100 rpm until uniformly stirred; S5: Continue to cool to 40-45°C, add the components of the efficacy phase F, and use magnetic stirring at a stirring speed of 50-100 rpm until uniformly stirred, and cool to room temperature to obtain the cleansing composition; The homogenization and emulsification process in step S3 and the cooling and stirring processes in steps S4 and S5 are all carried out under a vacuum condition of -0.06 MPa to -0.1 MPa to ensure that the emulsion system is delicate, stable, and free of bubbles.

[0067] Example 2 A specific test example 1: a facial cleansing composition with deep penetration-cleansing synergistic effect, specifically, by mass percentage: The base phase A includes 1.0 wt% of the first moisturizing agent sodium polyglutamate, 0.2 wt% of the stabilizer tetrasodium dicarboxymethyl aspartate, and 3.0 wt% of the second moisturizing agent glycerol; deionized water is used to make up to 100 mL; Thickened Phase B includes 0.8 wt% of the thickener Polyacrylate Crosspolymer-6 and 5.0 wt% of the third humectant Butylene Glycol; Efficacy Phase C includes 1.5 wt% of the skin conditioning agent polyglyceryl-10 laurate; The cleansing ingredients of the cleansing phase D include 3.0 wt% Candida albiflora / glucose / rapeseed oleate ferment product, 8.0 wt% of the emollient caprylic / capric triglyceride; The efficacy E phase includes 0.5 wt% of the first active ingredient, tocopheryl acetate; The efficacy F phase includes 2.0wt% of a composite plant extract, which contains 0.5wt% of papaya extract, 0.5wt% of salvia miltiorrhiza root powder, 0.4wt% of angelica root powder, 0.2wt% of houttuynia cordata powder, 0.2wt% of scutellaria baicalensis root powder and 0.2wt% of honeysuckle flower extract.

[0068] Specific Test Example 2: A facial cleansing composition with deep penetration-cleansing synergistic effect, specifically, by mass percentage: The base A phase includes 1.5 wt% of the first moisturizing agent sodium polyglutamate, 0.2 wt% of the stabilizer tetrasodium dicarboxymethyl aspartate, and 3.0 wt% of the second moisturizing agent glycerol; and 100 mL of deionized water; Thickened Phase B includes 1.0 wt% of the thickener Polyacrylate Crosspolymer-6 and 6.0 wt% of the third humectant Butylene Glycol; Efficacy Phase C includes 2.0 wt% of the skin conditioning agent polyglyceryl-10 laurate; The cleansing ingredients of the cleansing phase D include 4.0 wt% Candida albiflora / glucose / rapeseed oleate ferment product, 10.0 wt% of the emollient caprylic / capric triglyceride; Efficacy phase E includes 0.5 wt% of the second active ingredient, ceramide NP; Efficacy phase F includes 3.0 wt% of a complex plant complex, which contains 0.75 wt% of papaya extract, 0.75 wt% of salvia miltiorrhiza root powder, 0.6 wt% of angelica root powder, 0.3 wt% of houttuynia cordata powder, 0.3 wt% of scutellaria baicalensis root powder and 0.3 wt% of honeysuckle flower extract.

[0069] Specific Test Example 3: A facial cleansing composition with deep penetration-cleansing synergistic effect, specifically, by mass percentage: The base A phase includes 0.8 wt% of the first moisturizing agent sodium polyglutamate, 0.2 wt% of the stabilizer tetrasodium dicarboxymethyl aspartate, and 3.0 wt% of the second moisturizing agent glycerol; deionized water is 100 mL; Thickened Phase B includes 0.6 wt% of the thickener Polyacrylate Crosspolymer-6 and 4.0 wt% of the third humectant Butylene Glycol; Efficacy Phase C includes 1.0 wt% of the skin conditioning agent polyglyceryl-10 laurate; The cleansing ingredients of the cleansing phase D include 2.0 wt% Candida albiflora / glucose / rapeseed oleate ferment product, 6.0 wt% emollient caprylic / capric triglyceride; The efficacy E phase includes 0.5 wt% of the first active ingredient, tocopheryl acetate; The efficacy F phase includes 1.5wt% of a composite plant extract, which contains 0.375wt% of papaya extract, 0.375wt% of salvia miltiorrhiza root powder, 0.3wt% of angelica root powder, 0.15wt% of houttuynia cordata powder, 0.15wt% of scutellaria baicalensis root powder and 0.15wt% of honeysuckle flower extract.

[0070] Comparative Test Example 1: The difference from Specific Test Example 1 is that the fermentation product of Candida albiflora / glucose / rapeseed oleate was not used in the cleaning phase D, but 5.0 wt% of a common surfactant sodium laureth sulfate (SLES) was used.

[0071] Comparative Test Example 2: The main difference from Specific Test Example 1 is that the non-efficacy F phase is used; secondly, the efficacy E phase uses the second active ingredient ceramide NP.

[0072] Comparative Test Example 3: The main difference from Specific Test Example 1 is that there is no caprylic / capric triglyceride in the cleansing D phase and no efficacy F phase.

[0073] The specific formulas of specific test examples 1-3 and comparative test examples 1-3 are shown in Table 1.

[0074] Table 1-1 Formula of the compositions of specific test examples 1-3 and comparative test examples 1-3 (unit: wt%) Table 1-2 Formulations of the compositions of specific test examples 1-3 and comparative test examples 1-3 (unit: wt%) The preparation method of the facial cleansing product comprising the composition of specific test examples 1-3 and comparative test examples 1-3 comprises the following specific steps: Step 1: Combine the ingredients of Phase A (deionized water, sodium polyglutamate, tetrasodium dicarboxymethyl aspartate, glycerin) and heat to 80°C. Combine the ingredients of Phase D (caprylic / capric triglyceride, Candida albiflora / glucose / rapeseed methyl ester ferment or SLES) and heat to 80°C. Step 2: Slowly add the thickening components of phase B (polyacrylate crosspolymer-6, butanediol) to phase A while stirring (stirring speed is 50-70 rpm) for 15-20 minutes until completely dissolved and transparent; Step 3: Under vacuum (-0.08 MPa) and high-speed stirring (stirring speed 5000 rpm), slowly pump the clean phase D into the main pot and homogenize and emulsify for 5 minutes; Step 4: Turn off the homogenizer, turn on stirring and cooling. When the temperature drops to 60°C, add the components of efficacy phase C and efficacy phase E, and stir evenly in a vacuum (-0.08MPa) (stirring speed 40-60rpm, stirring time 10 minutes); Step 5: Continue cooling to 40°C, add the functional phase F component, stir evenly in a vacuum (-0.08MPa) (stirring speed 40-60rpm, stirring time 10 minutes), continue cooling to 25°C, discharge, and obtain the final cleansing product.

[0075] The following is an efficacy test and result analysis of the facial cleansing products prepared by specifically including the compositions of Test Examples 1-3 and Comparative Test Examples 1-3.

[0076] 1. Cleaning power evaluation Evaluation method: Apply 0.05g of a commercially available waterproof liquid foundation evenly onto artificial skin. After drying to form a film, take 0.5g of the cleansed sample to be tested (Test Examples 1-3, Comparative Test Examples 1-3), add water and rub for 30 seconds, then rinse thoroughly with clean water. Use a skin tester (such as VISIA) to capture high-definition images before and after cleansing. Image analysis software then calculates the residual percentage of the liquid foundation. The lower the residual percentage, the stronger the cleansing power. The evaluation results are shown in Table 2.

[0077] Table 2 Cleaning power test results Results Analysis: The data in Table 2 shows that all test examples and comparative examples demonstrated strong cleaning performance. Based on the residual rate results, Comparative Example 1, which used the powerful SLES surfactant, achieved the best cleaning effect. However, the present invention, which optimized the formulation and incorporated biosurfactants, achieved comparable cleaning results. However, the biosurfactant system was milder, demonstrating that this technical solution ensures that its cleansing products achieve the goal of gentle, efficient cleansing.

[0078] 2. Evaluation of skin barrier function and moisturizing effect Evaluation Method: 30 healthy volunteers were recruited and randomly divided into 6 groups, with 5 participants in each group. The products of Specific Test Examples 1-3 and Comparative Test Examples 1-3 were used once daily, morning and evening, for 14 consecutive days. Transepidermal water loss (TEWL) and stratum corneum water content were measured on the inner forearm using a skin tester (e.g., Tewameter® or Corneometer®) on day 0 and day 14, respectively. An increase in TEWL indicates barrier damage, while a decrease indicates barrier repair. An increase in stratum corneum water content indicates improved moisturizing. The evaluation results are shown in Table 3.

[0079] Table 3 Skin barrier function test results Results Analysis: Table 3 clearly demonstrates that after 14 days of use of a traditional SLES cleanser (Comparative Example 1), skin TEWL values ​​significantly increased and water content decreased, confirming damage to the skin barrier. Although a composite plant extract was also incorporated into Comparative Example 1, the results did not significantly increase the water content of the stratum corneum. On the other hand, the formulations of Comparative Examples 2 and 3, while utilizing biosurfactants, did not incorporate a composite plant extract. Therefore, while there was no significant negative impact on the skin barrier, the improvement was limited. However, after 14 days of use, the volunteers' TEWL values ​​significantly decreased and stratum corneum water content increased significantly in specific Examples 1-3 of the present invention. This strongly demonstrates that the present composition formula not only effectively cleanses but also effectively repairs the skin barrier and enhances the skin's moisturizing capacity. These results demonstrate that the cleansing phase D and the efficacy phase F in the present composition formula exhibit a synergistic effect.

[0080] The volunteers were tested using VISIA-Timm and VISIA-Tcl skin testers, respectively. Figure 1 and Figure 2 As shown, Figure 1 This is a photo of a skin test of a volunteer using the product prepared in specific Test Example 1 of the present invention; Figure 1 As can be seen from the comparison of (a) to (d), after the volunteers used the product of specific test example 1 for 14 days, their skin barrier was significantly improved, and the water content of the stratum corneum was greatly increased; Figure 2 This is a photo of the skin test of another volunteer using the product prepared in specific test example 1 of the present invention. Figure 2 From the comparison of (a) to (d), it can be seen that after the volunteers used the product of specific test example 1 for 14 days, the skin barrier was significantly improved and the water content of the stratum corneum was greatly increased.

[0081] The above volunteer examples can prove that the present invention constructs a "deep penetration-cleansing synergy" mechanism through the synergistic effect of the cleansing efficacy phase D and the synergistic efficacy phase F, enhances the skin barrier function, improves the skin's hydration state, and achieves a "healthier the more you wash" skin care effect.

[0082] 3. In vitro permeability test Methods: To verify the "deep penetration and synergistic cleansing" effect of the present invention, in vitro permeation experiments were conducted using a Franz diffusion cell. Niacinamide was used as a model active (added at 2% in each formulation) and Bama Xiang pig skin served as a permeation barrier. Each sample was applied to the membrane for 2 minutes, followed by rinsing with water to simulate a cleansing process. The liquid in the receiving cell was collected, and the cumulative permeation of niacinamide was determined by high-performance liquid chromatography (HPLC). The results are shown in Table 4.

[0083] Table 4 In vitro cumulative permeation of nicotinamide (μg / cm²) Results Analysis: In vitro permeability is the core effect of the composition of the present invention. Table 4 presents key data demonstrating this in vitro permeability. The results show that the niacinamide penetration of Specific Test Examples 1-3 was significantly higher than that of all comparative test examples. Compared with Comparative Test Example 3 (containing a biosurfactant but without a synergistic plant extract complex), the penetration of Specific Test Example 1 increased by approximately 140%. Furthermore, based on the results of Specific Test Examples 1-3, Specific Test Example 2 achieved the highest penetration. Analysis of the formula revealed that Specific Test Example 2 contained the largest amount of complex plant extracts. This demonstrates the effectiveness of the complex plant extracts in Efficacy Phase F, which requires each component. In particular, Danshen root powder and Angelica root powder significantly enhanced the penetration of the active ingredient during the brief cleansing process. Compared with Comparative Test Example 1 (SLES system), the penetration was lower, indicating that simply disrupting the barrier does not lead to effective penetration. These experimental results strongly confirm the scientific and effective nature of the "deep penetration-synergistic cleansing" mechanism proposed in this invention.

[0084] 4. Consumer Usage Test Methods: Fifty consumers who self-reported combination or dry-sensitive skin were recruited. Specific Test Example 1 and Comparative Test Example 1 were used in a double-blind, left-right comparison for seven consecutive days. A questionnaire was used to collect consumers' ratings of their product experience (on a scale of 1-5, with higher scores indicating a positive evaluation). The results are shown in Table 5.

[0085] Table 5 Consumer experience ratings Results: Consumers' subjective evaluations were highly consistent with objective instrumental testing results. Specifically, Test Example 1 significantly outperformed Comparative Test Example 1 using SLES in terms of "mildness" and "hydration," while performing comparably in terms of "freshness," demonstrating that the composition of the present invention achieves a perfect combination of effective cleansing and a gentle feel. The extremely high "overall satisfaction" rating also demonstrates that the product of the present invention provides consumers with an excellent skincare experience in actual use.

[0086] 5. Product stability test To verify product stability, the final product prepared in Specific Experimental Example 1 was tested for stability during storage. The appearance, color, and odor of the final product were observed at 0 days, 10 days, 20 days, and 30 days, and the total bacterial count, mold and yeast count, thermotolerant coliforms, Staphylococcus aureus, and Pseudomonas aeruginosa were tested. The specific results are shown in Table 6.

[0087] Table 6 Product stability test results Before each test, the product was first observed for changes in appearance, such as delamination, precipitation of solids or transparent liquids, or other inhomogeneities. The color was then observed for changes, and finally, the odor was smelled for changes. Various bacterial colony tests were then performed. As shown in Table 6, the product of Specific Test Example 1 showed no changes over 30 days, including no delamination, precipitation of solids or transparent liquids, or other inhomogeneities. Furthermore, no bacterial colonies were detected, demonstrating that the product of the present invention exhibited stable performance and high stability during storage.

[0088] In summary, the present invention provides a cleansing composition with deep penetration-cleansing synergistic effects. Through innovative formula design, it successfully solves the difficult problem of balancing cleaning power and mildness, and cleaning and skin care effects in the existing technology. It has significant creativity and practical value and has broad market prospects.

[0089] It should be noted that, in this document, the terms "comprises," "includes," or any other variations thereof are intended to encompass non-exclusive inclusion, such that a process, method, article, or apparatus comprising a series of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or apparatus comprising the element.

[0090] The embodiments of the present invention are described above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned specific embodiments. The above-mentioned specific embodiments are merely illustrative and not restrictive. Under the guidance of the present invention, ordinary technicians in this field can also make many forms, such as equivalent replacements of various components, without departing from the scope of protection of the present invention and the claims, and all of these are protected by the present invention.

Claims

1. A facial cleansing composition with deep penetration-cleansing synergistic effect, characterized in that: The cleansing composition with deep penetration and synergistic cleansing effects comprises a cleansing phase D and an efficacy phase F; the cleansing phase D comprises a biosurfactant and an emollient; the biosurfactant is a fermentation product of Candida albicans / glucose / rapeseed oleate; the efficacy phase F comprises a composite plant extract; the composite plant extract comprises papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria root powder, and honeysuckle flower extract; The mass ratio of the biosurfactant to the composite plant extract is (1-2):

1.

2. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 1, characterized in that: The mass ratio of papaya extract, salvia miltiorrhiza root powder, angelica root powder, houttuynia cordata powder, scutellaria root powder and honeysuckle extract in the efficacy F phase is (4-6):(4-6):(3-5):(1-3):(1-3):(1-3).

3. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 1, characterized in that: The cleansing composition with deep penetration-cleansing synergistic effect further comprises a basic phase A, a thickening phase B, an efficacy phase C and an efficacy phase E; The base phase A comprises 0.5-5 wt% of a first moisturizing agent, 2-5 wt% of a second moisturizing agent, 0.1-2 wt% of a stabilizer, and the balance is made up of water; The thickening phase B comprises 0.1-2 wt% of a thickener and 2-10 wt% of a third moisturizing agent; The efficacy phase C comprises 0.1-5 wt% of a skin conditioning agent; The efficacy E phase includes 0.1-5wt% active ingredients; The cleansing efficacy D phase also includes 5-15 wt% of an emollient.

4. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 3, characterized in that: The first moisturizing agent includes sodium polyglutamate, glycosyl trehalose and / or erythritol; or, the second moisturizing agent is glycerol; or, the third moisturizing agent includes butylene glycol, propylene glycol and / or pentylene glycol.

5. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 3, characterized in that: The stabilizers include tetrasodium dicarboxymethylaspartate, sodium phytate and / or a dipotassium hydrogen phosphate / potassium dihydrogen phosphate buffer pair.

6. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 3, characterized in that: The thickener in the thickening phase B includes polyacrylate crosspolymer-6 and / or ammonium polyacryloyldimethyltaurate; alternatively, the skin conditioning agent in the efficacy phase C is a nonionic emulsifier including polyglyceryl-10 laurate and / or polyglyceryl-3 diisostearate; alternatively, the efficacy phase E includes active ingredients with antioxidant efficacy and / or active ingredients with barrier repair efficacy.

7. The facial cleansing composition with deep penetration-cleansing synergistic effect according to claim 3, characterized in that: The emollients in the cleansing phase D include hydrogenated polydidecene, caprylic / capric triglyceride and / or jojoba seed oil.

8. Use of the facial cleansing composition with deep penetration-cleansing synergistic effect according to any one of claims 1 to 7 in the preparation of facial cleansing products, characterized in that: The types of facial cleansing products include oil-in-water emulsion type, gel / gel type, paste or cream type, oil type, powder type or solid soap type.

9. A new facial cleansing product, characterized in that: The novel facial cleansing product comprises the facial cleansing composition with deep penetration-cleansing synergistic effect according to any one of claims 1 to 7.

10. The preparation method of the novel facial cleanser according to claim 9, characterized in that: The following steps are involved: S1: Mix the components of base phase A evenly, heat to 75-85°C to obtain base phase A, and set aside; The components of the cleansing phase D are mixed evenly and heated to 75-85°C to obtain the cleansing phase D, which is set aside. S2: The components of the thickening phase B are dispersed in the base phase A and stirred until completely dissolved to obtain a mixed phase. S3: Under stirring conditions, the cleansing phase D mixed evenly in step S1 is slowly added to the mixed phase obtained in step S2, and high-speed stirring is performed at a speed of 3000-5000 rpm to homogenize and emulsify. S4: Cooling is started, the temperature is lowered to 55-65°C, the components of the efficacy phases C and E are added, and the mixture is stirred evenly. S5: The temperature is further lowered to 40-45°C, the components of the efficacy phase F are added, the mixture is stirred evenly, and the mixture is cooled to room temperature to obtain the novel facial cleanser. The homogenizing and emulsifying process in step S3 and the cooling and stirring processes in steps S4 and S5 are all carried out under a vacuum condition of -0.06 MPa to -0.1 MPa.

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