Fat-burning oral liquid

By using synephrine in the fat burning oral liquid to activate fat decomposition and green tea polyphenols to oxidize fatty acids, combined with plant charcoal powder to block intestinal absorption, the problem of poor effectiveness of existing fat burning products is solved, and efficient fat decomposition and taste improvement are achieved.

CN120754168APending Publication Date: 2025-10-10GUANGZHOU BENHAO BRAND SERVICE CO LTD
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Patent Information

Application Number
CN202511062634.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-31
Publication Date
2025-10-10

AI Technical Summary

Technical Problem

Existing fat-burning oral liquids lack active substances that directly promote fat decomposition, are not designed with ingredients that block intestinal fat absorption, are less effective in treating excessive dietary fat intake, and have a bitter taste that affects user experience.

Method used

Synephrine in the unripe fruit extract of bitter orange is used to directly stimulate β3-adrenergic receptors to promote the release of glycerol from fat cells. Green tea polyphenols activate the AMPK pathway to increase CPT-1 enzyme activity and accelerate fatty acid β-oxidation. At the same time, plant charcoal powder is used to block intestinal fat absorption, and fennel volatile oil and silymarin are used to inhibit fat synthesis. Pineapple concentrate and apple concentrate are combined to mask the bitter taste.

Benefits of technology

Significantly increases fat decomposition rate, reduces dietary fat absorption, improves digestive discomfort, provides natural sweetness, avoids cardiovascular side effects, and enhances the effect on people with a high-fat diet.

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Abstract

The invention discloses a fat-burning oral liquid, and relates to the technical field of oral liquids, and the fat-burning oral liquid comprises the following components by weight: 0.8-1.5% of a plant-derived alkaloid active component; 15-30% of a fruit juice concentrate; 0.5 to 5% of a plant synergistic interaction composition; 0.01%-0.1% of a preservative; 0.05 to 0.3 percent of a thickening agent; 0.1%-0.5% of an acidifying agent; 0.01%-0.1% of a flavoring agent; the plant source alkaloid active ingredient is a bitter orange immature fruit extract, synephrine accounts for 5-8% of the total weight of the extract, the fruit juice concentrate comprises pineapple concentrated juice and apple concentrated juice, the weight ratio of the pineapple concentrated juice to the apple concentrated juice is (1.5: 1)-(3: 1), and the total soluble solid content is greater than or equal to 65-degree Brix. The invention solves the problems that the existing compound fruit vinegar juice and cyperus esculentus meal oligosaccharide indirectly regulate metabolism, lack active substances for directly promoting lipolysis, do not design components for blocking intestinal fat absorption, only depend on synthesis inhibition and decomposition promotion, and have poor effect on excessive intake of dietary fat, and in addition, the cistanche juice has earthy smell, and is easy to eat. And the compound fruit vinegar juice has strong acerbity and influences the eating of users.
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Description

Technical Field

[0001] The present invention relates to the technical field of oral liquids, in particular to a fat burning oral liquid. Background Art

[0002] In the fight against obesity, a global health challenge, oral fat-burning products have always held a key position due to their convenience. Traditional solutions rely primarily on three main approaches: chemically synthesized drugs, strict lifestyle interventions (diet and exercise), and naturally derived dietary supplements. While drugs such as orlistat can inhibit lipase, their effects are limited to intestinal fat absorption and are often accompanied by significant gastrointestinal discomfort such as oily stools, leading to low compliance. Central nervous system appetite suppressants such as sibutramine, which have been banned due to serious cardiovascular risks, highlight the potential systemic side effects of synthetic drugs. While lifestyle interventions are the cornerstone of health, they require strong self-discipline, are difficult to adhere to long-term, and their effects are slow to show. In recent years, natural plant extracts have become a research and development focus due to their relatively high safety profile and potential for multi-target regulation. Green tea extract has been widely demonstrated to promote energy expenditure and lipolysis by activating the AMPK signaling pathway, enhancing lipoxygenase activity, and slightly increasing metabolic rate (approximately 4%). Garcinia cambogia extract (the main active ingredient is hydroxycitric acid (HCA)) competitively inhibits ATP-citrate lyase, thereby hindering the de novo synthesis of fatty acids and cholesterol. Caffeine, as a central nervous system stimulant, not only increases metabolic rate but also synergistically enhances adipose tissue lipolysis by stimulating catecholamine release. Capsaicinoids induce thermogenesis and activate brown adipose tissue by stimulating transient receptor potential vanilloid type 1 (TRPV1) channels. Furthermore, white kidney bean extract (an α-amylase inhibitor) indirectly reduces energy intake by blocking the hydrolysis of carbohydrates into absorbable sugars. Existing public document: CN119924425B, "A fat-reducing and metabolism-promoting oral liquid and its preparation process," includes the following steps: preparation of Cistanche deserticola juice; preparation of compound fruit vinegar juice; preparation of cyperus oleifera meal oligosaccharides; preparation of a compound concentrated liquid of citronella fruit; and preparation of a fat-reducing and metabolism-promoting oral liquid. This invention uses the compound fruit vinegar juice to inhibit the activity of lipase, reducing fat synthesis; cyperus oleifera meal oligosaccharides promote the growth and reproduction of beneficial bacteria such as Bifidobacterium and Lactobacillus, thereby assisting in fat reduction; and the compounding of citronella fruit simultaneously inhibits fat synthesis and promotes fat decomposition, more effectively reducing body fat accumulation and fundamentally resolving the problem of fat accumulation. Through the synergistic action of multiple ingredients and angles, the effects of fat reduction and metabolism promotion are effectively achieved. The above-mentioned technology mainly relies on compound fruit vinegar juice and jatropha meal oligosaccharides to indirectly regulate metabolism. It lacks active substances that directly promote fat decomposition, and no ingredients are designed to block intestinal fat absorption. It only relies on inhibiting synthesis and promoting decomposition, and is less effective for excessive dietary fat intake. In addition, Cistanche juice has an earthy smell, and the compound fruit vinegar juice has a strong sour and astringent feeling, which affects users' consumption. For this reason, a fat burning oral liquid is provided. Summary of the Invention

[0003] The purpose of the present invention is to provide a fat burning oral liquid to solve the technical problems raised in the above background technology, such as the lack of active substances that directly promote fat decomposition, the lack of ingredients that block intestinal fat absorption, and poor effect on excessive dietary fat intake.

[0004] To achieve the above object, the present invention provides the following technical solution: a fat burning oral liquid comprising the following components by weight percentage: Plant-derived alkaloid active ingredients 0.8-1.5%; Juice concentrate 15-30%; Plant synergistic composition 0.5-5%; Preservatives 0.01-0.1%; Thickener 0.05-0.3%; Acidifier 0.1-0.5%; Flavoring 0.01-0.1%; Water-based carrier 55-75%.

[0005] Preferably, the plant-derived alkaloid active ingredient is an extract of unripe bitter orange fruit, wherein synephrine accounts for 5-8% of the total weight of the extract.

[0006] Preferably, the fruit juice concentrate comprises pineapple juice concentrate and apple juice concentrate in a weight ratio of 1.5:1-3:1, and the total soluble solids content is ≥65°Brix.

[0007] Preferably, the plant synergistic composition comprises the following components: Green tea polyphenol extract 40-60%; Fennel fruit volatile oil 20-35%; Silymarin 15-25%.

[0008] Preferably, the weight ratio of the green tea polyphenol extract to the bitter orange extract is 1:3-1:5.

[0009] Preferably, the fat burning oral liquid further comprises: 0.5-1.2% of plant charcoal powder, the particle size of which is ≤10 μm, the plant charcoal powder is activated by citric acid, and the specific surface area is ≥800 m 2 / g.

[0010] Preferably, the preservative is potassium sorbate.

[0011] Preferably, the thickening agent is xanthan gum.

[0012] Preferably, the acidifying agent is citric acid.

[0013] Preferably, the flavoring agent is natural peppermint oil or pineapple essence.

[0014] Compared with the prior art, the present application has the following advantages: (1) The present application directly stimulates β3-adrenergic receptor through synephrine in bitter orange extract, promotes the release of glycerol from fat cells, activates AMPK pathway through green tea polyphenols, improves CPT-1 enzyme activity, accelerates fatty acid β oxidation, reduces fat from the source of energy metabolism, avoids gastric irritation through silymarin inhibition of fat synthesis, has stronger liver targeting, promotes fat decomposition through synephrine, improves fat decomposition rate, and directly reduces dietary fat absorption through plant charcoal powder.

[0015] (2) Citric acid is weaker than acetic acid, reduces mucous membrane irritation, anise volatile oil relieves intestinal spasm, improves indigestion, pineapple concentrate + apple concentrate provides a natural sweet base, masks the bitter orange astringency, plant charcoal powder adsorbs bile acids, is more effective for high-fat diet groups, and avoids cardiovascular side effects without caffeine ingredients. DETAILED DESCRIPTION

[0016] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all embodiments.

[0017] Embodiment one An embodiment provided by the present application: a fat-burning oral liquid, comprising the following components in percentage of total weight: Plant-derived alkaloid active ingredient 1.25%; Fruit juice concentrate 12%; Plant synergistic composition 73.55%; Preservative 0.05%; Thickening agent 0.15%; Acidifying agent 0.25%; Flavoring agent 0.03%; Water-based carrier 73.55%.

[0018] Further, the plant-derived alkaloid active ingredient is bitter orange immature fruit extract, wherein synephrine accounts for 5-8% of the total weight of the extract.

[0019] Furthermore, the juice concentrate comprises pineapple concentrated juice and apple concentrated juice, the weight ratio of the two is 1.5:1-3:1, and the total soluble solid content is ≥65°Brix.

[0020] Furthermore, the plant synergistic composition comprises the following components: Green tea polyphenol extract 40-60%; Fennel fruit volatile oil 20-35%; Artichoke silymarin 15-25%.

[0021] Furthermore, the weight ratio of the green tea polyphenol extract to the bitter orange extract is 1:3-1:5.

[0022] Furthermore, the fat burning oral solution also contains: 0.5-1.2% plant charcoal powder, the particle size of which is ≤10μm, and the plant charcoal powder is activated by citric acid and has a specific surface area of ​​≥800m 2 / g.

[0023] Furthermore, the preservative is potassium sorbate.

[0024] Furthermore, the thickener is xanthan gum.

[0025] Furthermore, the acidulant is citric acid.

[0026] Furthermore, the flavoring agent is natural mint oil or pineapple essence.

[0027] Preparation method of the fat burning oral liquid: Step 1: Take 55-75% of the formula volume of purified water, temperature 40-45°C, add 0.1-0.5% of acidifier, stir and dissolve until the pH is 3.5-4.5, add 0.05-0.3% of thickener, and high-speed shear at 2000-3000 rpm for 10 minutes to form a homogeneous colloid; Step 2: Mix 15-30% of the juice concentrate with 0.8-1.5% of the plant-derived alkaloid under inert gas protection, control the temperature at 50-55°C, and stir for 30 minutes to fully disperse the synephrine in the juice micelles; Step 3: Mix 0.5-5% of the plant synergistic composition with the product obtained in step 2, gradually cool to 35-40°C, add 0.5-1.2% of plant carbon powder, and perform ultrasonic treatment at 20kHz for 5 minutes to break up agglomerates; Step 4: Add preservatives ≤ 0.1%, flavoring 0.01-0.1%, and the remaining water carrier, and adjust the volume to 100%, maintaining the temperature at 30±2℃; Step 5: Perform two-stage homogenization: the first stage is 20MPa to break up large particles, the second stage is 35MPa to refine the particles to a size of ≤50μm, and vacuum degassing is performed at -0.08MPa for 10 minutes to remove dissolved oxygen and prevent polyphenol oxidation; Step 6: sterilize the product through a 0.22 μm microporous filter membrane, fill it with nitrogen and fill it into brown glass ampoules, seal it and pasteurize it at 70°C for 15 minutes.

[0028] Example 2 An embodiment of the present invention provides a fat burning oral liquid, comprising the following components by weight: Bitter orange extract (containing 7% synephrine) 1.43%; Green tea polyphenol extract (EGCG 55%) 0.60% Fennel fruit essential oil 0.15%; Silymarin 0.30%; pineapple juice concentrate 18.0%; Apple juice concentrate 6.0%; Water-based carrier 68.17%; Xanthan gum 0.20%; Citric acid 0.30%: Natural peppermint oil 0.05%.

[0029] Example 3 An embodiment of the present invention provides a fat burning oral liquid, comprising the following components by weight: Bitter orange extract (containing 8% synephrine) 1.50%; Green tea polyphenol extract 1.00%; Activated plant charcoal powder (1000m 2 / g) 1.20%; Fennel essential oil + artichoke complex 1.30%; pineapple juice concentrate 22.0%; Water-based carrier 68.65%; Xanthan gum 0.25%; Citric acid 0.35%; Potassium sorbate 0.08%; Pineapple-mint compound flavor 0.07%.

[0030] Comparative Example 1 Cassia seed extract 15%; Nuciferine 0.6%; Hawthorn concentrated juice 10%; Konjac flour 2%; Preservative 0.1%.

[0031] Comparative Example 2 Caffeine 1.2%; L-carnitine 2.5%; Artificial sweetener 0.05%; Citric acid 0.3%; Potassium sorbate 0.08%.

[0032]

[0033] Among them, the triple effects of bitter orange β-3 receptor activation + green tea EGCG inhibition of COMT + fennel PPARα activation are significantly better than caffeine in comparative example 2, namely central stimulation. The specific surface area of ​​activated plant charcoal is higher than that of konjac flour, the adsorption selectivity is improved, and the plant charcoal has directional adsorption. Compared with comparative example 1, it adsorbs lipid metabolites but does not affect electrolytes. Green tea polyphenols prolong the half-life of synephrine to a lower level than comparative example 2, avoiding peak and valley fluctuations in blood drug concentration.

[0034] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations that come within the meaning and range of equivalents of the claims be embraced therein.

Claims

1. Fat burning oral liquid, characterized in that, The total weight percentage contains the following components: Plant-derived alkaloid active ingredients 0.8-1.5%; Juice concentrate 15-30%; Plant synergistic composition 0.5-5%; Preservatives 0.01-0.1%; Thickener 0.05-0.3%; Acidifier 0.1-0.5%; Flavoring 0.01-0.1%; Water-based carrier 55-75%.

2. The fat burning oral liquid according to claim 1, characterized in that: The plant-derived alkaloid active ingredient is an extract of unripe bitter orange fruit, wherein synephrine accounts for 5-8% of the total weight of the extract.

3. The fat burning oral liquid according to claim 2, characterized in that: The fruit juice concentrate comprises pineapple concentrated juice and apple concentrated juice, the weight ratio of the two is 1.5:1-3:1, and the total soluble solid content is ≥65°Brix.

4. The fat burning oral liquid according to claim 3, characterized in that: The plant synergistic composition comprises the following components: Green tea polyphenol extract 40-60%; Fennel fruit volatile oil 20-35%; Silymarin 15-25%.

5. The fat burning oral liquid according to claim 4, characterized in that: The weight ratio of the green tea polyphenol extract to the bitter orange extract is 1:3-1:

5.

6. The fat burning oral liquid according to claim 1, characterized in that Also contains: 0.5-1.2% plant charcoal powder, with a particle size of ≤10μm, plant charcoal powder activated by citric acid, with a specific surface area of ​​≥800m 2 / g.

7. The fat burning oral liquid according to claim 6, characterized in that: The preservative is potassium sorbate.

8. The fat burning oral liquid according to claim 7, characterized in that: The thickener is xanthan gum.

9. The fat burning oral liquid according to claim 8, characterized in that: The acidulant is citric acid.

10. The fat burning oral liquid according to claim 8, characterized in that: The flavoring agent is natural mint oil or pineapple essence.

Citation Information

Patent Citations

  • An oral liquid for reducing fat and promoting metabolism and its preparation process

    CN119924425B