Sugarcane field herbicide composition

Abstract

The invention belongs to the technical field of herbicides, and particularly relates to a sugarcane field herbicide composition. The invention relates to a herbicide composition for a sugarcane field. The herbicide composition for the sugarcane field is formed by binary compounding of propyrisulfuron, indoxacarb, quinolone or pyroxasulfone. When the propyrisulfuron is compounded with the indolinone-ethyl, the quinolone or the pyroxasulfone according to a certain mass ratio, the co-toxicity coefficient of the compounded composition on weeds is greater than 120, a synergistic interaction effect is shown, and the control effect on the weeds in the sugarcane field can be improved. In the compound composition, the weeding action mechanisms of the propyrisulfuron are different from the weeding action mechanisms of the indolinone-ethyl, the quinolone or the pyroxasulfone, so that accumulation and development of weed drug resistance are effectively delayed, and the weed drug resistance management cost is further reduced. Therefore, the compound composition provided by the invention can provide support for developing medicaments for preventing and removing weeds in the sugarcane field.

Description

Technical Field

[0001] This invention belongs to the field of herbicide technology, and specifically relates to a herbicide composition for sugarcane fields. Background Technology

[0002] Propyrisulfuron is a selective, broad-spectrum sulfonylurea herbicide, belonging to the selective, systemic, post-emergence foliar application class. It is an acetolactate synthase (ALS) inhibitor, which inhibits the biosynthesis of key amino acids (valine, leucine, and isoleucine), hindering cell division, suppressing weed growth, and ultimately causing weed death. It can be absorbed not only through weed leaves but also through roots and stem bases, and translocated throughout the entire weed plant. Propyrisulfuron controls grasses such as barnyard grass, duckweed, arrowhead, and goosegrass, as well as broadleaf and sedges, and is particularly effective against sulfonylurea-resistant weeds.

[0003] During sugarcane production, weeds compete with sugarcane plants for nutrients, affecting their growth. While herbicides can control weeds in sugarcane fields, the effectiveness of single herbicides is limited, and long-term use of a single herbicide can lead to the accumulation of herbicide resistance in weeds, resulting in reduced efficacy. Although increasing the application dosage can temporarily improve efficacy, this exacerbates the development of resistance and causes pesticide residues and increased environmental pollution. Combining different herbicidal activities can effectively solve these problems; therefore, researching compound herbicide combinations for controlling weeds in sugarcane fields is of great significance.

[0004] There are currently no reports of compounding promethazine with indolesulfanil, quinclorac, or sulfopyrazine.

[0005] The information disclosed in this background section is intended only to enhance the understanding of the overall background of the invention and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art. Summary of the Invention

[0006] The purpose of this invention is to provide a herbicide composition for sugarcane fields.

[0007] To achieve the above objectives, the present invention provides the following technical solution: A sugarcane field herbicide composition, wherein the sugarcane field herbicide composition is a binary compound of promethazine sulfadiazine and indole-3-methyl, quinalazine or sulfopyrazosulfuron.

[0008] For even better results, the mass ratio of the compound of promethazine and indolesulfanil is 1-7:7-1.

[0009] For even better results, the mass ratio of the compound of promethazine and quinclorac is 1-10:10-1.

[0010] For even better results, the mass ratio of the compound of promethazine and sulfonylpyrazine is 1-3:25-1.

[0011] The present invention also provides the application of the sugarcane field herbicide composition in the preparation of herbicides for controlling weeds in sugarcane fields.

[0012] For even better results, the sugarcane field weeds include goosegrass, bermudagrass, cyperus, and maidenhair fern.

[0013] Compared with the prior art, the present invention has the following beneficial effects: (1) When the present invention combines promethazine with indole-3-methyl, quinalazine or sulfonylpyrazine in a certain mass ratio, the co-toxicity coefficient of the compound combination against goosegrass weeds is greater than 120, showing a synergistic effect and improving the control effect on sugarcane weeds.

[0014] (2) The herbicidal mechanism of the compound combination of the present invention is different from that of indole-3-methyl, quinalazine or sulfonylpyrazine, which is conducive to effectively delaying the accumulation and development of herbicide resistance in weeds, thereby reducing the cost of herbicide resistance management.

[0015] Therefore, the compound combination of the present invention can support the development of agents for controlling weeds in sugarcane fields. Detailed Implementation

[0016] The following is a clear and complete description of the technical solution of this invention patent. Obviously, the described embodiments are some, but not all, of the embodiments of this invention.

[0017] Example: Indoor bioactivity test of the combination of promethazine and pyrisulfuron 1. Experimental weeds Goosegrass: Seeds collected from sugarcane fields.

[0018] 2. Test reagents 99% Promethazine-sulfuron technical grade (Wuhan Xinxin Jiali Biotechnology Co., Ltd.), 99% Indole-methyl technical grade (Haitaitan Technology Co., Ltd.), 98% Quinalazine technical grade (Liaoning Xianda Agricultural Science Co., Ltd.), 98% Sulfonazole technical grade (Shandong Jingbo Agricultural Chemical Technology Co., Ltd.) The above test reagents were dissolved in dimethyl sulfoxide and then diluted with 0.1% Tween-80 aqueous solution to prepare single-agent stock solutions. Based on the results of the preliminary test, multiple groups of ratios were set up. Then, each single-agent stock solution and each group of ratio mixtures were diluted with 0.1% Tween-80 aqueous solution to prepare 5 mass concentration gradients. The above reagents were prepared and used immediately.

[0019] 3. Test methods: (Refer to NY / T 1155.4-2006 Guidelines for Indoor Bioassay Testing of Pesticides - Herbicides - Part 4: Activity Assay Test - Foliar Spray Method) Fill plastic pots (12cm in diameter) 3 / 4 full with sterilized soil and thoroughly moisten the soil by drip irrigation from the bottom of the pot. Then, evenly scatter 20 goosegrass seeds on the soil surface in each pot and cover with 0.5-1.0cm of soil. Transfer the pots to a greenhouse at 25℃ with 12 hours of light for cultivation. When the weed seedlings reach the 3-leaf stage, thin them out, leaving 5 seedlings of uniform growth in each pot for bioassay.

[0020] The above-mentioned pesticide solution was sprayed onto the stems and leaves of weed seedlings using a mobile sprayer. Each treatment was replicated four times, with a 0.1% Tween-80 aqueous solution treatment serving as a blank control. The fresh weight of the above-ground portion of the weeds was weighed 14 days after application, and the fresh weight control efficacy was calculated. Then, the efficacy of each single agent and different mixtures was calculated using DPS software. 50 The co-toxicity coefficient (CTC value) of the mixture was calculated using the Sun Yunpei method.

[0021] 4. Calculation Method

[0022] In the above formula: E --Fresh weight efficacy (%) C --Comparison of fresh weight of the above-ground portion of weeds (g); T --Fresh weight (g) of the aboveground portion of the weeds.

[0023]

[0024] In the above formula: ATI --Measured toxicity index of the mixture; S --ED of standard reagents 50 The unit is g ai / hm2; M --ED of the test reagent 50 The unit is g ai / hm 2 .

[0025]

[0026] In the above formula: TTI --Theoretical toxicological index of the mixture; TI A --Toxicity index of drug A; P A --Percentage content of drug A in the mixture, expressed as percentage (%). TI B --Toxicity index of drug B; P B--The percentage content of drug B in the mixture, expressed as a percentage (%).

[0027]

[0028] In the above formula: CTC --Cotoxicity coefficient; ATI --Measured toxicity index of the mixture; TTI --Theoretical toxicity index of mixed formulations.

[0029] 5. Pharmaceutical Evaluation Based on the cotoxicity coefficient ( CTC The synergistic effect of drug mixtures was evaluated, with CTC ≤ 80 indicating an antagonistic effect, 80 < CTC < 120 indicating an additive effect, and CTC ≥ 120 indicating a synergistic effect. The experimental results are shown in Table 1-3.

[0030] Table 1. Results of indoor bioactivity assays of the combination of propazin and indolesulfanilamide on Eleusine indica. Test reagents Mass ratio <![CDATA[ED 50 (g a.i. / hm 2 )]]> ATI TT1 CTC Promethazine sulfadiazine -- 27.5104 100.0000 -- -- Indole-3-butanol -- 33.9248 81.0923 -- -- Promethazine + Indolesulfanilamide 1：7 18.1427 151.6334 83.4558 181.6932 1：3 25.5683 107.5957 85.8192 125.3749 1：1 21.8140 126.1135 90.5461 139.2809 3：1 23.5666 116.7347 95.2731 122.5264 7：1 19.4899 141.1521 97.6365 144.5689 Table 1 shows that when promethazine and indolesulfanil are combined in a mass ratio of 1-7:7-1, the co-toxicity coefficient against goosegrass is greater than 120, exhibiting a synergistic effect. This indicates that the combination of promethazine and indolesulfanil in this invention can improve the control effect on weeds such as goosegrass in sugarcane fields.

[0031] Table 2. Results of indoor bioactivity assays of the combination of propazin and quinclorac on Eleusine indica. Test reagents Mass ratio <![CDATA[ED 50 (g a.i. / hm 2 )]]> ATI TT1 CTC Promethazine sulfadiazine -- 27.5104 100.0000 -- -- Quinacridone -- 42.2539 65.1074 -- -- Promethazine + Quinalazine 1：10 29.3144 93.8460 68.2794 137.4441 1：7 26.8519 102.4523 69.4689 147.4793 1：3 22.3930 122.8527 73.8305 166.3982 1：1 27.6501 99.4948 82.5537 120.5213 3：1 13.8276 198.9528 91.2768 217.9664 7：1 9.4485 291.1616 95.6384 304.4400 10：1 14.9752 183.7064 96.8279 189.7246 Table 2 shows that when promethazine and quinclorac are combined at a mass ratio of 1-10:10-1, the co-toxicity coefficient against goosegrass is greater than 120, exhibiting a synergistic effect. This indicates that the combination of promethazine and quinclorac in this invention can improve the control effect on weeds such as goosegrass in sugarcane fields.

[0032] Table 3. Results of indoor bioactivity assays of the combination of promethazine and sulfonylpyrazole with *Eleusine indica*. Test reagents Mass ratio <![CDATA[ED 50 (g a.i. / hm 2 )]]> ATI TT1 CTC Promethazine sulfadiazine -- 27.5104 100.0000 -- -- Sulfonazole -- 63.7481 43.1549 -- -- Promethazine + Sulfonazole 1：25 47.5244 57.8869 45.3412 127.6695 1：15 31.6285 86.9798 46.7077 186.2216 1：7 37.9226 72.5435 50.2605 144.3351 1：3 35.6583 77.1501 57.3661 134.4871 1：1 24.7482 111.1612 71.5774 155.3021 3：1 25.9308 106.0916 85.7887 123.6661 Table 3 shows that when promethazine and sulfonylpyrazole are combined at a mass ratio of 1-3:25-1, the co-toxicity coefficient against goosegrass is greater than 120, exhibiting a synergistic effect. This indicates that the combination of promethazine and sulfonylpyrazole in this invention can improve the control effect on goosegrass and other weeds in sugarcane fields.

[0033] In summary, when promethazine-sulfuron is combined with indole-methyl, quinclorac, or sulfonylpyrazole in a certain mass ratio, the co-toxicity coefficient against *Eleusine indica* is greater than 120, demonstrating a synergistic effect and improving the control efficacy against weeds in sugarcane fields. Furthermore, the different herbicidal mechanisms of promethazine-sulfuron compared to indole-methyl, quinclorac, or sulfonylpyrazole in the compound formulation of this invention are beneficial in effectively delaying the accumulation and development of herbicide resistance in weeds, thereby reducing the cost of herbicide resistance management. Therefore, the compound formulation of this invention can provide support for the development of herbicides for controlling weeds in sugarcane fields.

[0034] The foregoing description of specific exemplary embodiments of the invention is for illustrative and explanatory purposes. These descriptions are not intended to limit the invention to the precise forms disclosed, and it will be apparent that many changes and variations can be made in accordance with the foregoing teachings. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application, thereby enabling those skilled in the art to implement and utilize various different exemplary embodiments of the invention, as well as various different choices and variations. The scope of the invention is intended to be defined by the claims and their equivalents.

Claims

1. A herbicide composition for sugarcane fields, characterized in that, The sugarcane field herbicide composition is a binary compound of promethazine sulfadiazine, indole-3-methyl, quinalazine, or sulfopyrazine.

2. The sugarcane field herbicide composition according to claim 1, characterized in that, The mass ratio of the compound of promethazine and indolesulfanil is 1-7:7-1.

3. The sugarcane field herbicide composition according to claim 1, characterized in that, The mass ratio of the compound of promethazine and quinclorac is 1-10:10-1.

4. The sugarcane field herbicide composition according to claim 1, characterized in that, The mass ratio of the compound of promethazine and sulfonylpyrazole is 1-3:25-1.

5. The use of the sugarcane field herbicide composition according to any one of claims 1-4 in the preparation of an herbicide for controlling weeds in sugarcane fields.

6. The application according to claim 5, characterized in that, The sugarcane field weeds include goosegrass, bermudagrass, cyperus rhizome, and maidenhair fern.

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