Sample analysis device and sample analysis method

Abstract

A sample analyzer (10) and a sample analysis method are provided. The sample analysis device (10) comprises a reaction container supply device (130), a sample distribution device (150), a reagent distribution device (160), a transfer device (140), a controller (200), a first determination device (110) and a second determination device (120), wherein the sample distribution device (150) is used for sucking a sample from a sample container (40) and distributing the sample to the reaction container provided by the reaction container supply device (130); the controller (200) is configured to: control the transfer device (140) to transfer the first reaction vessel (20) provided by the reaction vessel supply device (130) to the first measurement device (110) for measurement of a blood coagulation test item; a transfer device (140) is controlled to transfer the second reaction container (30) provided by the reaction container supply device (130) to a second measurement device (120) for measurement of non-clotting test items; any one reaction vessel provided by the reaction vessel supply device (130) can be selectively used as the first reaction vessel (20) or the second reaction vessel (30). The sample analysis device (10) has a blood coagulation detection function and a non-blood coagulation detection function, and is simple in structure and low in cost.

Description

Sample analysis device and sample analysis method Technical Field

[0001] The present application relates to the field of in vitro diagnostic equipment, and in particular to a sample analysis device and a sample analysis method. Background Art

[0002] In clinical tests related to coagulation, in addition to using coagulation methods, immunoturbidimetry, and chromogenic substrate methods to measure routine coagulation test items, it is sometimes necessary to assist with the determination of some molecular markers for better clinical application. Due to the low content of the analyte, the determination of these molecular markers generally adopts chemiluminescence methods, typically such as the four thrombosis items (thrombin-antithrombin complex TAT, plasmin-antiplasmin complex PIC, tissue plasminogen activator-plasminogen activator inhibitor complex tPAI.C, thrombomodulin TM). In traditional technology, if auxiliary molecular marker determination is needed in clinical tests related to coagulation, two blood samples need to be drawn from the patient, one tube is placed on a coagulation analyzer for the determination of coagulation test items, and the other tube is placed on an immunoassay analyzer for the determination of molecular markers. This test method is relatively cumbersome and requires two blood samples to be drawn from the patient.

[0003] In order to solve the problems of the above-mentioned traditional technology, the related technology provides a sample analysis device with both coagulation detection function and immunoassay function, that is, an integrated machine for coagulation detection and immunoassay. The working principle of the sample analysis device is as follows: when a sample needs to be tested for coagulation, the sample needle of the coagulation detection unit first draws the sample from the sample container and distributes it to the coagulation reaction container, and then transfers the coagulation reaction container from the turntable of the coagulation detection unit to the incubation device of the coagulation detection unit for incubation, and then to the coagulation determination device for determination of the coagulation detection item; when a sample needs to be tested for immunoassay, the sample needle of the coagulation detection unit first draws the sample from the sample container and distributes it to the coagulation reaction container, and then transfers the coagulation reaction container from the turntable of the coagulation detection unit to the transfer part, and then the clamp of the immunoassay unit takes out the coagulation reaction container and puts it into the immunoassay unit, and then the sample needle of the immunoassay unit draws the sample from the coagulation reaction container containing the sample and distributes it to the immunoassay container for incubation and determination of the immunoassay item. Among them, the coagulation reaction container and the immunoassay container are two different reaction containers.

[0004] The sample analysis device provided by the above-mentioned related technologies has the following deficiencies in specific applications: (1) Since coagulation detection and immunoassay use two different reaction containers, two different reaction container supply devices are required to provide the two different reaction containers. Even the grippers, incubation structures, etc. of the two detection units cannot be reused, resulting in the sample analysis device having the defects of complex structure, high cost, and large size. (2) The samples of the immunoassay project must first be allocated to the coagulation reaction container of the coagulation detection unit for transfer, and then the coagulation reaction container containing the samples for the immunoassay project is transferred to the immunoassay unit for repackaging of the samples, which seriously affects the detection efficiency of the immunoassay project. In addition, each immunoassay project requires the consumption of an additional coagulation reaction container in addition to the immunoassay reaction container, thereby increasing the number of coagulation reaction containers consumed.

[0005] Summary of the Invention

[0006] The first purpose of the present application is to provide a sample analysis device, which aims to solve the technical problems of complex structure and high cost of the integrated machine of coagulation detection and immunoassay in the related art.

[0007] To achieve the above objectives, the present application provides a solution: a sample analysis device comprising:

[0008] A reaction vessel supply device, wherein the reaction vessel supply device is used to provide reaction vessels;

[0009] a sample distributing device, configured to draw a sample from a sample container and distribute at least a portion of the drawn sample to the reaction container provided by the reaction container supply device;

[0010] a reagent dispensing device for sucking a reagent from a reagent container and dispensing at least a portion of the sucked reagent into the reaction container provided by the reaction container supply device;

[0011] At least two measuring devices, the at least two measuring devices include a first measuring device and a second measuring device, the first measuring device is used to measure coagulation test items on the sample, and the second measuring device is used to measure non-coagulation test items on the sample;

[0012] A transfer device, the transfer device is used to transfer the reaction container;

[0013] a controller configured to: control the transfer device to transfer the first reaction container provided by the reaction container supply device to the first measuring device, and control the first measuring device to perform a coagulation test on a first specimen prepared from at least a sample and a first type of reagent in the first reaction container;

[0014] The controller is further configured to: control the transfer device to transfer the second reaction container provided by the reaction container supply device to the second measuring device, and control the second measuring device to measure a non-coagulation test item on a second sample prepared from at least the sample and the second type of reagent in the second reaction container;

[0015] Wherein, any one of the reaction containers provided by the reaction container supply device can be selectively used as the first reaction container or the second reaction container.

[0016] In one embodiment, the reaction container supply device has a single output channel for outputting the reaction containers, and any reaction container output from the single output channel can be selectively used as the first reaction container or the second reaction container; or,

[0017] The reaction container supply device has at least two output channels for respectively outputting the reaction containers, and any reaction container output from each output channel can be selectively used as the first reaction container or the second reaction container.

[0018] In one embodiment, the sample analysis device includes a single reaction container supply device, and the first reaction container and the second reaction container are reaction containers provided by the same single reaction container supply device.

[0019] As an embodiment, the first reaction container and the second reaction container are the same reaction container provided by the same reaction container supply device; and / or,

[0020] The first reaction container and the second reaction container are reaction containers with the same shape and size.

[0021] As an embodiment, the controller is further configured to: first control the sample dispensing device to dispense the sample into the first reaction container provided by the reaction container supply device; then control the transfer device to transfer the first reaction container loaded with the sample into the first measuring device;

[0022] The controller is further configured to: first control the sample dispensing device to dispense the sample to the second reaction container provided by the reaction container supply device; and then control the transfer device to transfer the second reaction container loaded with the sample to the second measurement device.

[0023] As an embodiment, the sample analysis device further includes a first identification component, the first identification component being used to identify the sample container before aspirating the sample from the sample container;

[0024] The controller is further configured to:

[0025] According to the feedback information of the first identification component, at least obtaining the to-be-tested test item of the sample in the sample container;

[0026] According to the test item of the sample, the reaction container provided by the reaction container supply device is selectively used as the first reaction container or the second reaction container.

[0027] In one embodiment, the controller selectively uses the reaction container provided by the reaction container supply device as the first reaction container or the second reaction container according to the test item of the sample, including:

[0028] When the test item of the sample to be tested includes a coagulation test item, at least one reaction container provided by the reaction container supply device is used as the first reaction container, the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the first reaction container provided by the reaction container supply device; the transfer device is controlled to transfer the first reaction container loaded with the sample to the first measuring device; the reagent dispensing device is controlled to draw a first type of reagent from the reagent container and distribute at least part of the drawn first type of reagent to the first reaction container loaded with the sample in the first measuring device; the first measuring device is controlled to measure the first test specimen prepared from at least the sample and the first type of reagent in the first reaction container;

[0029] When the test items of the sample to be tested include non-coagulation test items, at least one reaction container provided by the reaction container supply device is used as the second reaction container, the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the second reaction container provided by the reaction container supply device; the transfer device is controlled to transfer the second reaction container loaded with the sample to the second measuring device, the reagent dispensing device is controlled to draw a second type of reagent from the reagent container and distribute at least part of the drawn second type of reagent to the second reaction container loaded with the sample in the second measuring device; the second measuring device is controlled to measure the second test sample prepared by at least the sample and the second type of reagent in the second reaction container;

[0030] The controller is further configured to: parse and obtain a measurement result of the sample according to feedback information from the first measurement device and / or the second measurement device.

[0031] As an embodiment, the reagent dispensing device includes a first reagent dispensing mechanism and a second reagent dispensing mechanism;

[0032] The sample analysis device further includes a first reagent tray and a second reagent tray, wherein the first reagent tray is used to carry a first reagent container, the first reagent container being loaded with a first type of reagent for performing a coagulation test, and the first reagent dispensing mechanism being used to draw the first type of reagent from the first reagent container and dispense the drawn first type of reagent into the first reaction container loaded with the sample;

[0033] The second reagent tray is used to carry a second reagent container, the second reagent container is loaded with a second type of reagent for performing non-coagulation test items, and the second reagent dispensing mechanism is used to draw the second type of reagent from the second reagent container and dispense the drawn second type of reagent into the second reaction container loaded with the sample;

[0034] The first assay device comprises a first incubation mechanism and a first assay component, wherein the first incubation mechanism is used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and the first assay component is used to assay a coagulation test item on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container;

[0035] The second measuring device includes a second incubation mechanism and a second measuring component. The second incubation mechanism is used to incubate the third liquid in the second reaction container containing at least the sample and the second type of reagent to produce a fourth liquid. The second measuring component is used to perform non-coagulation detection items on the second sample made of at least the fourth liquid in the second reaction container.

[0036] In one embodiment, the controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the first transfer area, and control the transfer device to transfer the first reaction container from the first transfer area to the first incubation mechanism;

[0037] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the first transfer area, and control the transfer device to transfer the second reaction container from the first transfer area to the second incubation mechanism.

[0038] As an embodiment, the first transfer area includes a first transfer position, a second transfer position and a third transfer position;

[0039] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the first intermediate transfer position, control the transfer device to transfer the first reaction container from the first intermediate transfer position to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism;

[0040] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the first transfer position, control the transfer device to transfer the second reaction container from the first transfer position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

[0041] As an embodiment, the first transfer area includes a fourth transfer position;

[0042] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the fourth transfer position, and control the transfer device to transfer the first reaction container from the fourth transfer position to the first incubation mechanism;

[0043] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the fourth transfer position, and control the transfer device to transfer the second reaction container from the fourth transfer position to the second incubation mechanism.

[0044] As an embodiment, the first transfer area includes a fifth transfer position and a sixth transfer position;

[0045] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the fifth intermediate transfer position, control the transfer device to transfer the first reaction container from the fifth intermediate transfer position to the sixth intermediate transfer position, and control the transfer device to transfer the first reaction container from the sixth intermediate transfer position to the first incubation mechanism;

[0046] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the fifth transfer position, control the transfer device to transfer the second reaction container from the fifth transfer position to the sixth transfer position, and control the transfer device to transfer the second reaction container from the sixth transfer position to the second incubation mechanism.

[0047] As an embodiment, the first transfer area includes a second transfer position and a third transfer position;

[0048] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism;

[0049] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

[0050] As an embodiment, the transfer device includes:

[0051] a first transfer mechanism, the first transfer mechanism being used to transfer the first reaction container loaded with the sample from the reaction container supply device to the first transfer area under the control of the controller, and being used to transfer the second reaction container loaded with the sample from the reaction container supply device to the first transfer area under the control of the controller;

[0052] a second transfer mechanism, configured to transfer the first reaction container located at the first transfer area and used for performing coagulation test items to the first incubation mechanism under the control of the controller;

[0053] A third transfer mechanism is used to transfer the second reaction container located in the first transfer area and used for performing non-coagulation test items to the second incubation mechanism under the control of the controller.

[0054] In one embodiment, the first transfer mechanism is used to transfer the reaction container loaded with the sample from the first reaction container supply device to the first intermediate transfer position under the control of the controller, and is used to transfer the second reaction container loaded with the sample from the reaction container supply device to the first intermediate transfer position under the control of the controller;

[0055] The transfer device further includes a fourth transfer mechanism, which is used to transfer the first reaction container located at the first transfer position and used for performing coagulation test item determination to the second transfer position under the control of the controller, and is used to transfer the second reaction container located at the first transfer position and used for performing non-coagulation test item determination to the third transfer position under the control of the controller;

[0056] The second transfer mechanism is used to transfer the first reaction container located at the second transfer position to the first incubation mechanism under the control of the controller;

[0057] The third transfer mechanism is used to transfer the second reaction container located at the third transfer position to the second incubation mechanism under the control of the controller.

[0058] As an embodiment, the fourth transfer mechanism is a track-type transfer mechanism, a turntable-type transfer mechanism, or a gripper-type transfer mechanism.

[0059] As an embodiment, the reagent dispensing device includes a third reagent dispensing mechanism;

[0060] The sample analysis device further includes a third reagent tray, the third reagent tray being used to carry a first reagent container and a second reagent container, the first reagent container being used to carry a first type of reagent for coagulation test items, and the second reagent container being used to carry a second type of reagent for non-coagulation test items;

[0061] The third reagent dispensing mechanism is used to draw the first type of reagent from the first reagent container and dispense the drawn first type of reagent into the first reaction container containing the sample, and is used to draw the second type of reagent from the second reagent container and dispense the drawn second type of reagent into the second reaction container containing the sample;

[0062] The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid;

[0063] The first measuring device further includes a first measuring component, the first measuring component being used to measure a coagulation test item on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container;

[0064] The second measuring device further includes a second measuring component configured to measure a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

[0065] As an embodiment, the transfer device includes:

[0066] a fifth transfer mechanism, the fifth transfer mechanism being used to transfer the first reaction container loaded with the sample from the reaction container supply device to the second transfer area under the control of the controller, and being used to transfer the second reaction container loaded with the sample from the reaction container supply device to the second transfer area under the control of the controller;

[0067] a sixth transfer mechanism, the sixth transfer mechanism being used to transfer the first reaction container located at the second transfer area to the third incubation mechanism under the control of the controller, and to transfer the second reaction container located at the second transfer area to the third incubation mechanism under the control of the controller;

[0068] A seventh transfer mechanism, wherein the seventh transfer mechanism is used to transfer the first reaction container located at the third incubation mechanism and used for performing coagulation detection item determination to the first measurement component under the control of the controller, and is used to transfer the second reaction container located at the third incubation mechanism and used for performing non-coagulation detection item determination to the second measurement component under the control of the controller.

[0069] As an embodiment, the second transfer area includes a seventh transfer position and an eighth transfer position;

[0070] The fifth transfer mechanism is used to transfer the first reaction container loaded with the sample from the reaction container supply device to the seventh transfer position under the control of the controller, and is used to transfer the second reaction container loaded with the sample from the reaction container supply device to the seventh transfer position under the control of the controller;

[0071] The transfer device further includes an eighth transfer mechanism, which is used to transfer the first reaction container located at the seventh transfer position to the eighth transfer position under the control of the controller, and is used to transfer the second reaction container located at the seventh transfer position to the eighth transfer position under the control of the controller;

[0072] The sixth transfer mechanism is used to transfer the first reaction container located at the eighth transfer position to the third incubation mechanism under the control of the controller, and is used to transfer the second reaction container located at the eighth transfer position to the third incubation mechanism under the control of the controller.

[0073] As an embodiment, the second transfer area includes a ninth transfer position and a tenth transfer position;

[0074] The fifth transfer mechanism is used to transfer the first reaction container loaded with the sample from the reaction container supply device to the ninth transfer position under the control of the controller, and the sixth transfer mechanism is used to transfer the first reaction container located at the ninth transfer position to the third incubation mechanism under the control of the controller;

[0075] The fifth transfer mechanism is also used to transfer the second reaction container loaded with the sample from the reaction container supply device to the tenth transfer position under the control of the controller, and the sixth transfer mechanism is also used to transfer the second reaction container located at the tenth transfer position to the third incubation mechanism under the control of the controller.

[0076] As an embodiment, the reagent dispensing device includes a fourth reagent dispensing mechanism and a fifth reagent dispensing mechanism;

[0077] The sample analysis device further includes a third reagent tray, the third reagent tray being used to carry a first reagent container and a second reagent container, the first reagent container being used to carry a first type of reagent for coagulation test items, and the second reagent container being used to carry a second type of reagent for non-coagulation test items;

[0078] The fourth reagent dispensing mechanism is used to draw the first type of reagent from the first reagent container of the third reagent disk and dispense at least part of the drawn first type of reagent into the first reaction container loaded with the sample;

[0079] The fifth reagent dispensing mechanism is used to draw the second type of reagent from the second reagent container of the third reagent disk and dispense at least part of the drawn second type of reagent into the second reaction container loaded with the sample;

[0080] The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid;

[0081] The first measuring device further includes a first measuring component, the first measuring component being used to measure a coagulation test item on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container;

[0082] The second measuring device further includes a second measuring component configured to measure a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

[0083] As an embodiment, the reagent dispensing device includes a sixth reagent dispensing mechanism and a seventh reagent dispensing mechanism;

[0084] The sample analysis device further includes a first reagent disc and a second reagent disc, wherein the first reagent disc is used to carry a first reagent container, and the first reagent container is loaded with a first type of reagent for performing coagulation test items;

[0085] The second reagent tray is used to carry a second reagent container, and the second reagent container is loaded with a second type of reagent for performing non-coagulation test items;

[0086] The sixth reagent dispensing mechanism is used to draw the first type of reagent from the first reagent container of the first reagent disk and dispense at least part of the drawn first type of reagent into the first reaction container loaded with the sample;

[0087] The seventh reagent dispensing mechanism is used to draw the second type of reagent from the second reagent container of the second reagent disk and dispense at least part of the drawn second type of reagent into the second reaction container loaded with the sample;

[0088] The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid;

[0089] The first measuring device further includes a first measuring component, the first measuring component being used to measure a coagulation test item on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container;

[0090] The second measuring device further includes a second measuring component configured to measure a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

[0091] As an embodiment, the non-coagulation test item measured by the second measuring device is an immunoassay item or a biochemical test item.

[0092] A second object of the present application is to provide a sample analysis device, the sample analysis device comprising:

[0093] a first identification component, the first identification component being used to identify a sample container loaded with a sample;

[0094] a second identification component, the second identification component being used to identify a reagent container, the reagent container comprising a first reagent container and a second reagent container, the first reagent container being loaded with a first type of reagent, and the second reagent container being loaded with a second type of reagent;

[0095] a sample distributing device for aspirating a sample from the sample container identified by the first identifying component and distributing at least a portion of the aspirated sample to a reaction container;

[0096] a reagent dispensing device for aspirating the first type of reagent from the first reagent container identified by the second identification component and dispensing at least a portion of the aspirated first type of reagent into the reaction container; and for aspirating the second type of reagent from the second reagent container identified by the second identification component and dispensing at least a portion of the aspirated second type of reagent into the reaction container;

[0097] At least two measuring devices, the at least two measuring devices include a first measuring device and a second measuring device, the first measuring device is used to measure coagulation test items on the sample, and the second measuring device is used to measure non-coagulation test items on the sample;

[0098] A controller configured to: obtain at least the test item of the sample in the sample container according to the feedback information of the first identification component; and obtain at least the information of the reagent in the reagent container according to the feedback information of the second identification component;

[0099] The controller is further configured to: control the sample dispensing device to draw a sample from the sample container identified by the first identification component and distribute at least a portion of the drawn sample to a first reaction container; control the reagent dispensing device to draw a first type of reagent from the first reagent container identified by the second identification component and distribute it to the first reaction container; and control the first measuring device to measure a coagulation test item on a first specimen prepared from at least the sample and the first type of reagent in the first reaction container;

[0100] The controller is further configured to: control the sample dispensing device to draw the sample from the sample container identified by the first identification component and distribute at least part of the drawn sample to the second reaction container; control the reagent dispensing device to draw the second type of reagent from the second reagent container identified by the second identification component and distribute it to the second reaction container; and control the second measuring device to perform non-coagulation test items on the second test specimen made of at least the sample and the second type of reagent in the second reaction container.

[0101] As an embodiment, the first reaction container and the second reaction container are the same reaction container; and / or,

[0102] The first reaction container and the second reaction container are reaction containers with the same shape and size.

[0103] As an embodiment, the sample analysis device further includes a transfer device, and the transfer device is used to transfer the reaction container;

[0104] The controller is further configured to:

[0105] When the test item of the sample to be tested includes a coagulation test item, at least one reaction container is used as the first reaction container, the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the first reaction container; the transfer device is controlled to transfer the first reaction container loaded with the sample to the first measuring device; the reagent dispensing device is controlled to draw the first type of reagent from the first reagent container and distribute at least part of the drawn first type of reagent to the first reaction container loaded with the sample in the first measuring device; the first measuring device is controlled to measure the first test specimen prepared from at least the sample and the first type of reagent in the first reaction container;

[0106] When the test items of the sample to be tested include non-coagulation test items, at least one reaction container is used as the second reaction container, the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the second reaction container; the transfer device is controlled to transfer the second reaction container loaded with the sample to the second measuring device, the reagent dispensing device is controlled to draw the second type of reagent from the second reagent container and distribute at least part of the drawn second type of reagent to the second reaction container loaded with the sample in the second measuring device; the second measuring device is controlled to measure the second test sample prepared by at least the sample and the second type of reagent in the second reaction container;

[0107] The measurement result of the sample is analyzed and obtained based on the feedback information of the first measurement device and / or the second measurement device.

[0108] As an embodiment, the reagent dispensing device includes a first reagent dispensing mechanism and a second reagent dispensing mechanism;

[0109] The sample analysis device further includes a first reagent tray and a second reagent tray, wherein the first reagent tray is used to carry the first reagent container;

[0110] The second reagent tray is used to carry the second reagent container;

[0111] The first assay device includes a first incubation mechanism and a first assay component. The first incubation mechanism is used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid. The first reagent dispensing mechanism is used to aspirate the first type of reagent from the first reagent container and dispense at least a portion of the aspirated first type of reagent into the first reaction container containing the sample. The first assay component is used to perform a coagulation test on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container.

[0112] The second measuring device includes a second incubation mechanism and a second measuring component. The second reagent dispensing mechanism is used to absorb the second type of reagent from the second reagent container and dispense at least part of the absorbed second type of reagent into the second reaction container loaded with the sample. The second incubation mechanism is used to incubate the third liquid in the second reaction container containing at least the sample and the second type of reagent to produce a fourth liquid. The second measuring component is used to perform non-coagulation detection items on the second sample made of at least the fourth liquid in the second reaction container.

[0113] As an embodiment, the sample analysis device further includes a transfer device, and the transfer device is used to transfer the reaction container;

[0114] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the reaction container supply device to the first transfer area, and control the transfer device to transfer the first reaction container from the first transfer area to the first incubation mechanism;

[0115] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the first transfer area, and control the transfer device to transfer the second reaction container from the first transfer area to the second incubation mechanism.

[0116] As an embodiment, the first transfer area includes a first transfer position, a second transfer position and a third transfer position;

[0117] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the sample loading position to the first intermediate transfer position, control the transfer device to transfer the first reaction container from the first intermediate transfer position to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism;

[0118] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the sample loading position to the first transfer position, control the transfer device to transfer the second reaction container from the first transfer position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

[0119] As an embodiment, the first transfer area includes a fourth transfer position;

[0120] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the sample loading position to the fourth transfer position, and control the transfer device to transfer the first reaction container from the fourth transfer position to the first incubation mechanism;

[0121] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the sample loading position to the fourth transfer position, and control the transfer device to transfer the second reaction container from the fourth transfer position to the second incubation mechanism.

[0122] As an embodiment, the first transfer area includes a fifth transfer position and a sixth transfer position;

[0123] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for performing a coagulation test from the sample loading position to the fifth intermediate transfer position, control the transfer device to transfer the first reaction container from the fifth intermediate transfer position to the sixth intermediate transfer position, and control the transfer device to transfer the first reaction container from the sixth intermediate transfer position to the first incubation mechanism;

[0124] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with a sample, and the sample loaded is used for non-coagulation detection items from the sample loading position to the fifth transfer position, control the transfer device to transfer the second reaction container from the fifth transfer position to the sixth transfer position, and control the transfer device to transfer the second reaction container from the sixth transfer position to the second incubation mechanism.

[0125] As an embodiment, the first transfer area includes a second transfer position and a third transfer position;

[0126] The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for coagulation test from the sample loading position to the second transfer position, and control the transfer device to transfer the first reaction container from the second transfer position to the first incubation mechanism;

[0127] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples, and the loaded samples are used for non-coagulation detection items from the sample loading position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

[0128] As an embodiment, the reagent dispensing device includes a third reagent dispensing mechanism;

[0129] The sample analysis device further includes a third reagent tray, the third reagent tray being used to carry the first reagent container and the second reagent container;

[0130] The third reagent dispensing mechanism is used to draw the first type of reagent from the first reagent container and dispense at least part of the drawn first type of reagent into the first reaction container containing the sample, and is used to draw the second type of reagent from the second reagent container and dispense at least part of the drawn second type of reagent into the second reaction container containing the sample;

[0131] The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid;

[0132] The first measuring device further includes a first measuring component, the first measuring component being used to measure a coagulation test item on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container;

[0133] The second measuring device further includes a second measuring component configured to measure a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

[0134] As an embodiment, the sample analysis device further includes a transfer device, and the transfer device is used to transfer the reaction container;

[0135] The controller is further configured to: control the transfer device to transfer the first reaction container loaded with the sample from the sample loading position to the seventh transfer position, control the transfer device to transfer the first reaction container located at the seventh transfer position to the eighth transfer position, and control the transfer device to transfer the first reaction container located at the eighth transfer position to the third incubation mechanism;

[0136] The controller is also configured to: control the transfer device to transfer the second reaction container loaded with the sample from the sample loading position to the seventh transfer position, control the transfer device to transfer the second reaction container located at the seventh transfer position to the eighth transfer position, and control the transfer device to transfer the second reaction container located at the eighth transfer position to the third incubation mechanism.

[0137] As an embodiment, the non-coagulation test item measured by the second measuring device is an immunoassay item or a biochemical test item.

[0138] A third object of the present application is to provide a sample analysis method, which includes a coagulation measurement step and a non-coagulation measurement step, wherein the coagulation measurement step includes the following steps:

[0139] controlling the reaction container supply device to provide a first reaction container;

[0140] Controlling the sample dispensing device to draw the sample from the sample container and dispensing at least a portion of the drawn sample into the first reaction container;

[0141] Controlling the reagent dispensing device to absorb a first type of reagent from a first reagent container, and dispensing at least a portion of the absorbed first type of reagent into the first reaction container;

[0142] controlling the first measuring device to measure a coagulation test item on a first sample prepared from at least a sample and the first type of reagent in the first reaction container;

[0143] The non-coagulation determination step comprises the following steps:

[0144] controlling the reaction container supply device to provide a second reaction container;

[0145] controlling the sample dispensing device to draw the sample from the sample container and to dispense at least a portion of the drawn sample into the second reaction container;

[0146] Controlling the reagent dispensing device to absorb the second type of reagent from the second reagent container, and dispensing at least part of the absorbed second type of reagent into the second reaction container;

[0147] controlling the second measuring device to measure a non-coagulation test item on a second sample prepared from at least the sample and the second type of reagent in the second reaction container;

[0148] Wherein, any one of the reaction containers provided by the reaction container supply device can be selectively used as the first reaction container or the second reaction container.

[0149] As an embodiment, the coagulation measurement step further comprises the steps of: controlling the transfer device to transfer the first reaction container, which is provided by the reaction container supply device and has been distributed with the sample by the sample dispensing device, to the first measurement device; and / or, after the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the first reaction container, and before the reagent dispensing device is controlled to draw the first type of reagent from the first reagent container and distribute at least part of the drawn first type of reagent to the first reaction container;

[0150] The non-coagulation measurement step further includes the step of controlling the transfer device to transfer the second reaction container provided by the reaction container supply device and having the sample distributed by the sample distribution device to the second measurement device after the sample distribution device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the second reaction container, and before the reagent distribution device is controlled to draw the second type of reagent from the second reagent container and distribute at least part of the drawn second type of reagent to the second reaction container.

[0151] As an embodiment, the sample analysis method further includes an identification step before the coagulation determination step and / or the non-coagulation determination step, and the identification step includes: controlling the first identification component to identify the sample container; obtaining at least the test items to be tested of the sample in the sample container based on the feedback information of the first identification component; when the test items to be tested of the sample include coagulation test items, executing the coagulation determination step; when the test items to be tested of the sample include non-coagulation test items, executing the non-coagulation determination step.

[0152] A fourth object of the present application is to provide a sample analysis method, the sample analysis method comprising an identification step, a coagulation measurement step, and a non-coagulation measurement step, wherein the identification step comprises the following steps:

[0153] Controlling the first identification component to identify the sample container loaded with the sample, and obtaining at least the to-be-tested test item of the sample in the sample container according to feedback information from the first identification component;

[0154] controlling the second identification component to respectively identify the first reagent container and the second reagent container, and obtaining at least information about the first type of reagent in the first reagent container and information about the second type of reagent in the second reagent container based on feedback information from the second identification component;

[0155] The coagulation determination step comprises the following steps:

[0156] Controlling the sample distributing device to draw a sample from the sample container identified by the first identifying component, and distributing at least a portion of the drawn sample to a first reaction container;

[0157] Controlling the reagent dispensing device to absorb the first type of reagent from the first reagent container identified by the second identification component, and dispensing at least part of the absorbed first type of reagent into the first reaction container;

[0158] controlling the first measuring device to measure a coagulation test item on a first sample prepared from at least a sample and the first type of reagent in the first reaction container;

[0159] The non-coagulation determination step comprises the following steps:

[0160] Controlling the sample distributing device to draw a sample from the sample container identified by the first identifying component, and distributing at least a portion of the drawn sample to a second reaction container;

[0161] Controlling the reagent dispensing device to absorb the second type of reagent from the second reagent container identified by the second identification component, and dispensing at least part of the absorbed second type of reagent into the second reaction container;

[0162] The second measuring device is controlled to measure a non-coagulation test item on a second sample prepared from at least a sample and a second type of reagent in the second reaction container.

[0163] As an embodiment, the coagulation measurement step further comprises the steps of: controlling a transfer device to transfer the first reaction container to which the sample has been distributed by the sample dispensing device, after the sample dispensing device is controlled to draw a sample from the sample container identified by the first identification component and distribute at least a portion of the drawn sample to the first reaction container, and before the reagent dispensing device is controlled to draw a first type of reagent from the first reagent container identified by the second identification component and distribute at least a portion of the drawn first type of reagent to the first reaction container; and / or,

[0164] The non-coagulation measurement step further includes the step of controlling the transfer device to transfer the second reaction container to which the sample has been allocated by the sample dispensing device after the sample dispensing device is controlled to draw the sample from the sample container identified by the first identification component and to distribute at least part of the drawn sample to the second reaction container, and before controlling the reagent dispensing device to draw the second type of reagent from the second reagent container identified by the second identification component and to distribute at least part of the drawn second type of reagent to the second reaction container: controlling the transfer device to transfer the second reaction container to which the sample has been allocated by the sample dispensing device to the second measurement device.

[0165] As an embodiment, the sample analysis method further comprises: if it is determined based on the feedback information of the first identification component that the test item of the sample to be tested includes a coagulation test item, executing the coagulation measurement step;

[0166] If it is determined based on the feedback information from the first identification component that the test items of the sample include non-coagulation test items, the non-coagulation determination step is performed.

[0167] The sample analysis device provided by the first purpose of the present application and the sample analysis method provided by the third purpose, by setting a first measuring device for measuring the coagulation detection item of the sample and setting a second measuring device for measuring the non-coagulation detection item of the sample, thereby realizing the integration of the coagulation detection function and the non-coagulation detection function. In addition, the present application realizes the integration of the coagulation detection function and the non-coagulation detection function by setting any reaction container provided by the reaction container supply device to be selectively used as the first reaction container for measuring the coagulation detection item or as the second reaction container for measuring the non-coagulation detection item, that is, the reaction container provided by the reaction container supply device can be used for both coagulation detection and non-coagulation detection, and the coagulation detection item and the non-coagulation detection item share the same reaction container supply device to provide the reaction container. In this way, the present application realizes the integration of the coagulation detection function and the non-coagulation detection function without configuring two different reaction container supply devices to supply the reaction container, thereby simplifying the structure of the sample analysis device and reducing the cost and volume of the sample analysis device. When the non-coagulation detection item determined by the second measuring device is an immune detection item, if it is necessary to assist in the determination of molecular markers in coagulation-related clinical tests, the sample analysis device of the present application can be used alone to perform the determination of coagulation detection items and the determination of molecular markers, which simplifies the operational process of molecular marker determination in coagulation-related clinical tests, and does not require the collection of samples from two sample containers from the patient, effectively reducing the amount of sample used.

[0168] The sample analysis device provided by the second purpose of this application and the sample analysis method provided by the fourth purpose of this application integrate coagulation and non-coagulation detection functions by providing a first measurement device for measuring coagulation detection items on the sample and a second measurement device for measuring non-coagulation detection items on the sample. In addition, when performing coagulation and non-coagulation detection on the sample, the sample is directly dispensed from the sample container to the reaction container corresponding to the detection item, and the reagent is directly dispensed from the reagent container to the reaction container corresponding to the detection item, without the need for secondary packaging of the sample and reagent. This effectively ensures the detection efficiency of each detection item and reduces the consumption of unnecessary reaction containers. BRIEF DESCRIPTION OF THE DRAWINGS

[0169] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0170] FIG1 is a schematic diagram of the composition of a sample analysis device provided in Example 1 of the present application;

[0171] FIG2 is a schematic structural diagram of a sample analysis device provided in Example 1 of the present application;

[0172] 3 is a schematic structural diagram of the common parts of the first measuring device and the second measuring device provided in Example 1 of the present application;

[0173] FIG4 is a schematic diagram of the measurement principle of the first measurement component provided in Example 1 of the present application;

[0174] FIG5 is a schematic diagram of the measurement principle of the second measurement component provided in Example 1 of the present application;

[0175] 6 is a schematic structural diagram of the common parts of the first measuring device and the second measuring device provided in Example 2 of the present application;

[0176] 7 is a schematic structural diagram of the common parts of the first measuring device and the second measuring device provided in Example 3 of the present application;

[0177] FIG8 is a schematic structural diagram of the common parts of the first measuring device and the second measuring device provided in Example 4 of the present application;

[0178] FIG9 is a schematic structural diagram of a sample analysis device provided in Example 5 of the present application;

[0179] FIG10 is a schematic structural diagram of a sample analysis device provided in Example 6 of the present application;

[0180] Figure 11 is a structural schematic diagram of the third incubation mechanism, the first reagent disk, the second reagent disk, the first measuring component and the second measuring component provided in Example 7 of the present application.

[0181] Explanation of the accompanying reference numerals: 10, sample analysis device; 100, analyzer execution body; 110, first measuring device; 111, first incubation mechanism; 112, first measuring component; 1121, first illumination component; 1122, first light receiving component; 1123, first measuring carrying component; 120, second measuring device; 121, second incubation mechanism; 122, second measuring component; 1221, second light receiving component; 1222, second measuring carrying component; 123, magnetic separation mechanism; 130, reaction container supply device; 140, transfer device; 141, first transfer mechanism; 142, second transfer mechanism; 143, third transfer mechanism; 144, fourth transfer mechanism; 145, ninth transfer mechanism; 146, fifth transfer mechanism; 147, sixth transfer mechanism; 148, seventh transfer mechanism; 149, eighth transfer mechanism; 150, sample dispensing device; 160, reagent dispensing device; 161, first reagent dispensing device Injection mechanism; 1611, mixed reagent dispensing mechanism; 1612, trigger reagent dispensing mechanism; 162, second reagent dispensing mechanism; 163, third reagent dispensing mechanism; 1631, first sub-reagent dispensing mechanism; 1632, second sub-reagent dispensing mechanism; 164, fourth reagent dispensing mechanism; 165, fifth reagent dispensing mechanism; 166, sixth reagent dispensing mechanism; 167, seventh reagent dispensing mechanism; 170, first reagent tray; 180, second reagent tray; 19 0. Sampling device; 191. Loading area; 192. Recovery area; 193. Scheduling mechanism; 101. First transfer area; 1011. First transfer position; 1012. Second transfer position; 1013. Third transfer position; 1014. Fourth transfer position; 200. Controller; 300. First identification component; 400. Human-computer interaction device; 500. Second identification component; 20. First reaction container; 30. Second reaction container; 40. Sample container; 50. Sample rack. DETAILED DESCRIPTION

[0182] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0183] It should be noted that all directional indications in the embodiments of the present application (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship and movement status between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.

[0184] In addition, the descriptions of "first", "second", etc. in this application are for descriptive purposes only and should not be understood as indicating or implying their relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined as "first" or "second" may explicitly or implicitly include at least one of such features. In addition, the technical solutions between the various embodiments can be combined with each other, but this must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0185] Example 1:

[0186] As shown in Figures 1 to 5, the sample analysis device 10 provided in the first embodiment of the present application includes an analyzer execution body 100 and a controller 200. The analyzer execution body 100 is used to perform sample detection items on the sample under the control of the controller 200. The controller 200 is used to parse and obtain the detection results of the sample based on the feedback information of the analyzer execution body 100. The sample detection items that the analyzer execution body 100 can perform on the sample include coagulation detection items and non-coagulation detection items, that is, the sample analysis device 10 of this embodiment integrates coagulation detection function and non-coagulation detection function. The sample analysis device 10 of this embodiment is an all-in-one machine for coagulation detection and non-coagulation detection.

[0187] As an embodiment, the analyzer execution body 100 includes at least two measuring devices, including a first measuring device 110 and a second measuring device 120. The first measuring device 110 is used to measure coagulation test items on the sample, and the second measuring device 120 is used to measure non-coagulation test items on the sample, thereby realizing the integration of coagulation test functions and non-coagulation test functions. In specific applications, different measuring devices can be selectively used to measure the patient's sample according to the clinical testing needs of different patients. For example, if a sample only needs to be measured for coagulation test items, only the first measuring device 110 is required to measure the sample; if a sample only needs to be measured for non-coagulation test items, only the second measuring device 120 is required to measure the sample; if a sample needs to be measured for both coagulation test items and non-coagulation test items, the first measuring device 110 and the second measuring device 120 are required to measure the sample at the same time.

[0188] In one embodiment, the analyzer execution body 100 further includes a reaction vessel supply device 130 and a transfer device 140. The reaction vessel supply device 130 is configured to provide reaction vessels, and the transfer device 140 is configured to transfer reaction vessels. The controller 200 is configured to control the transfer device 140 to transfer a first reaction vessel 20 provided by the reaction vessel supply device 130 to the first measurement device 110, and to control the first measurement device 110 to perform a coagulation test on a first specimen prepared from at least a sample and a first-type reagent in the first reaction vessel 20. The controller 200 is further configured to control the transfer device 140 to transfer a second reaction vessel 30 provided by the reaction vessel supply device 130 to the second measurement device 120, and to control the second measurement device 120 to perform a non-coagulation test on a second specimen prepared from at least a sample and a second-type reagent in the second reaction vessel 30. Any reaction vessel provided by the reaction vessel supply device 130 can be selectively used as either the first reaction vessel 20 or the second reaction vessel 30. In this embodiment, the reaction containers provided by the reaction container supply device 130 can be used for both coagulation detection and non-coagulation detection. The coagulation detection items and the non-coagulation detection items share the same reaction container supply device to provide reaction containers. In this way, the integration of coagulation detection function and non-coagulation detection function can be achieved without configuring two different reaction container supply devices 130 to supply reaction containers, thereby simplifying the structure of the sample analysis device 10 and reducing the cost and volume of the sample analysis device 10.

[0189] As an embodiment, the analyzer execution body 100 further includes a sample dispensing device 150, which is configured to draw a sample from the sample container 40 and distribute at least a portion of the drawn sample to a reaction container provided by the reaction container supply device 130. The reaction container here can be the first reaction container 20 or the second reaction container 30 described above. In a specific application, if the sample test items to be performed on the sample only include coagulation tests that can be performed by the first measurement device 110, the sample dispensing device 150 only needs to draw the sample from the sample container 40 and distribute it to the first reaction container 20. If the sample test items to be performed on the sample only include non-coagulation tests that can be performed by the second measurement device 120, the sample dispensing device 150 only needs to draw the sample from the sample container 40 and distribute it to the second reaction container 30. If the sample test items to be performed on the sample include both coagulation tests that can be performed by the first measurement device 110 and non-coagulation tests that can be performed by the second measurement device 120, the sample dispensing device 150 needs to draw the sample from the sample container 40 and distribute it to the first reaction container 20 and the second reaction container 30 respectively. When a patient needs to undergo sample testing items that include coagulation testing items that can be performed by the first measuring device 110 and non-coagulation testing items that can be performed by the second measuring device 120, a common sample container 40 can be used to load the patient's samples. The sample distribution device 150 draws the sample from the single sample container 40 and distributes it to the first reaction container 20 and the second reaction container 30 respectively, thereby helping to reduce the amount of sample collected from the patient and the consumption of sample containers 40.

[0190] In one embodiment, the sample dispensing device 150 includes a sample needle, a first aspiration and discharge drive component, and a first motion drive component. The sample needle is used to aspirate and discharge the sample. The first aspiration and discharge drive component provides driving force for the sample needle to aspirate and discharge the sample. The first motion drive component is used to drive the sample needle in two-dimensional or three-dimensional motion, thereby moving the sample needle to different working positions, such as the standby position, sample aspiration position, sample loading position, and washing position.

[0191] As an embodiment, the first suction and discharge drive component is a syringe. Of course, in specific applications, the configuration of the first suction and discharge drive component is not limited to this, for example, it can also be a pump or a positive and negative pressure drive structure.

[0192] As an embodiment, the analyzer execution body 100 includes a single sample distribution device 150, and the single sample distribution device 150 includes a single sample needle. Coagulation detection items and non-coagulation detection items share the same sample distribution device 150 and the same sample needle for distributing samples. The structure is simple, which helps to reduce the cost of the sample analysis device 10.

[0193] In one embodiment, the reaction vessel supply device 130 has a single output channel for outputting reaction vessels, and any reaction vessel outputted from the single output channel can be selectively used as either the first reaction vessel 20 or the second reaction vessel 30. The single output channel outputs the reaction vessels one by one, and depending on the test requirements, any reaction vessel outputted from the single output channel can be selected for either a coagulation test or a non-coagulation test. Because the sample analyzer 10 dispenses samples via a single sample needle of a single sample dispenser 150, sample dispensing can only be performed from one reaction vessel at a time. Therefore, the reaction vessel supply device 130 can meet the supply requirements of reaction vessels by using a single output channel to output reaction vessels. Of course, in specific applications, the setting method of the reaction container supply device 130 is not limited to this. For example, as an alternative embodiment, the reaction container supply device 130 has at least two output channels for outputting reaction containers respectively, and any reaction container output from each output channel can be selectively used as the first reaction container or the second reaction container. During the operation of the sample analysis device 10 of this alternative embodiment, only one output channel outputs the reaction container at the same time, and the remaining output channels are mainly used as backups, so that when an output channel in use fails and requires maintenance or the operator needs to perform other processing on the output channel, it can switch to another output channel to continue outputting the reaction container, thereby ensuring the continuity of operation of the sample analysis device 10.

[0194] As an embodiment, the sample analysis device 10 includes a single reaction container supply device 130, and the first reaction container 20 and the second reaction container 30 are reaction containers provided by the same single reaction container supply device 130. The first reaction container 20 is used to carry samples of coagulation test items for reaction and measurement, and the second reaction container 30 is used to carry samples of non-coagulation test items for reaction and measurement. In this embodiment, the first reaction container 20 used by the first measurement device 110 to measure coagulation test items and the second reaction container 30 used by the second measurement device 120 to measure non-coagulation test items are reaction containers provided by the same reaction container supply device 130, that is, the first measurement device 110 and the second measurement device 120 share the same reaction container supply device 130, and there is no need to configure a reaction container supply device 130 for each of the first measurement device 110 and the second measurement device 120, thereby simplifying the structure of the sample analysis device 10 and reducing the cost and volume of the sample analysis device 10.

[0195] In one embodiment, both the first reaction container 20 and the second reaction container 30 are disposable reaction containers. That is, after carrying the sample and completing the corresponding test item, the first reaction container 20 and the second reaction container 30 are discarded and recycled, without the need for cleaning and reuse within the sample analysis device 10. This helps simplify the structure and operating procedures of the sample analysis device 10. Of course, in specific applications, the sample analysis device 10 may include two different measurement devices that both use disposable reaction containers, or at least one measurement device that uses a reusable reaction container.

[0196] In one embodiment, the first reaction container 20 and the second reaction container 30 are identical in shape and / or size. Whether the first reaction container 20 and the second reaction container 30 are identical in shape or size, this facilitates transport and transfer of the first reaction container 20 and the second reaction container 30 using the same structure, thereby simplifying the structure of the sample analysis device 10.

[0197] In one embodiment, the first reaction vessel 20 and the second reaction vessel 30 have the same shape, including both the outer shape and the inner shape of the first reaction vessel 20 and the second reaction vessel 30. Of course, in a specific application, as an alternative embodiment, the first reaction vessel 20 and the second reaction vessel 30 may have the same shape, or the first reaction vessel 20 and the second reaction vessel 30 may have the same outer shape but different inner shapes.

[0198] In one embodiment, the first reaction vessel 20 and the second reaction vessel 30 are of the same size, including having the same external dimensions and internal dimensions. Of course, in a specific application, as an alternative embodiment, the first reaction vessel 20 and the second reaction vessel 30 may have the same shape, or the first reaction vessel 20 and the second reaction vessel 30 may have the same external dimensions but different internal dimensions.

[0199] As an embodiment, the first reaction container 20 and the second reaction container 30 are the same type of reaction container provided by the same reaction container supply device 130. The first reaction container 20 and the second reaction container 30 are the same type of reaction container, which specifically means that the first reaction container 20 and the second reaction container 30 have the same shape and size, and the first reaction container 20 and the second reaction container 30 can be manufactured using the same processing equipment and processing technology. In this embodiment, the first reaction container 20 and the second reaction container 30 are configured as the same type of reaction container. On the one hand, this helps reduce the number of consumables of the sample analysis device 10. On the other hand, it helps to eliminate the need for the transfer device 140 to provide two transfer structures of different shapes and / or sizes for the first reaction container 20 and the second reaction container 30, thereby simplifying the structure of the transfer device 140.

[0200] In one embodiment, the reaction vessel supply device 130 includes a silo, a directional conveying mechanism, and a buffer tray. The silo is used to load and store reaction vessels. The directional conveying mechanism is used to adjust the reaction vessels in the silo to an upward-facing position and transport them to the buffer tray. The buffer tray is used to carry reaction vessels with their openings facing upward. A sample loading station is located on the buffer tray of the reaction vessel supply device 130. A sample dispensing device 150 is used to draw samples from sample containers 40 and distribute them to reaction vessels on the buffer tray. A first transfer mechanism 141 is used to transport sample-loaded reaction vessels from the buffer tray to a first transfer station 1011. The silo is used for operators to store bulk reaction vessels and then pick up and transport them individually to the directional conveying mechanism. The silo has a hopper for loading bulk reaction vessels. The directional conveying mechanism adjusts the reaction vessels' position so that their openings are always facing vertically upward. The silo then transports the reaction vessels to the buffer tray for caching, awaiting sample dispensing. The buffer tray is the above-mentioned output channel, or the buffer tray and part of the directional conveying mechanism constitute the above-mentioned output channel.

[0201] As an embodiment, the sample analysis device 10 includes a single reaction vessel supply device 130, and the reaction vessel supply device 130 includes a single silo, a single directional conveying mechanism and a single cache tray. This embodiment adopts a single silo, a single directional conveying mechanism and a single cache tray to meet the reaction vessel supply needs of the first measuring device and the second measuring device. It has a simple structure, low cost and small size. Of course, in specific applications, the setting method of the reaction vessel supply device 130 is not limited to this. For example, as an alternative embodiment, the reaction vessel supply device 130 may also include two or more silos, a single directional conveying mechanism and a single cache tray, and the two or more silos can be switched for use; or, as another alternative embodiment, the reaction vessel supply device 130 may also include two or more silos, two or more directional conveying mechanisms and a single cache tray, and the two or more silos and the two or more directional conveying mechanisms can be switched for use.

[0202] As an embodiment, the controller 200 is further configured to: first control the sample dispensing device 150 to dispense the sample to the first reaction container 20 provided by the reaction container supply device 130; and then control the transfer device 140 to transfer the first reaction container 20 loaded with the sample to the first measuring device 110. In this embodiment, the first reaction container 20 transferred by the transfer device 140 to the first measuring device 110 is a reaction container that has already been loaded with the sample. That is, when the sample in a sample container 40 needs to be measured by the first measuring device 110 for a coagulation test item, the sample dispensing device 150 is first controlled to dispense the sample to the first reaction container 20, and then control the transfer device 140 to transfer the loaded first reaction container 20 from the sample loading position to the first measuring device 110. This ensures that the arrangement of the sample dispensing device 150 is not affected by the internal structure and position of the first measuring device 110, thereby reducing the movement stroke of the sample needle. Of course, in a specific application, as an alternative implementation, the first reaction container 20 may be transferred first and then the sample may be distributed. That is, the transfer device 140 may be controlled to transfer the empty first reaction container 20 from the reaction container supply device 130 to the first measuring device 110, and then the sample distribution device 150 may be controlled to draw the sample from the sample container 40 and distribute it into the first reaction container 20 in the first measuring device 110.

[0203] As an embodiment, the controller 200 is further configured to: first control the sample dispensing device 150 to dispense the sample to the second reaction container 30 provided by the reaction container supply device 130; and then control the transfer device 140 to transfer the second reaction container 30 loaded with the sample to the second measuring device 120. In this embodiment, the second reaction container 30 transferred by the transfer device 140 to the second measuring device 120 is a reaction container that has already been loaded with the sample. That is, when the sample in a sample container 40 needs to be measured by the second measuring device 120 for a non-coagulation test item, the sample dispensing device 150 is first controlled to dispense the sample to the second reaction container 30, and then control the transfer device 140 to transfer the loaded second reaction container 30 from the sample loading position to the second measuring device 120. In this way, the arrangement of the sample dispensing device 150 is not affected by the internal structure and position of the second measuring device 120, which helps to reduce the movement stroke of the sample needle. Of course, in a specific application, as an alternative implementation, the second reaction container 30 may be transferred first and then the sample may be distributed, that is, the transfer device 140 may be controlled to transfer the empty second reaction container 30 from the reaction container supply device 130 to the second measuring device 120, and then the sample dispensing device 150 may be controlled to draw the sample from the sample container 40 and distribute it into the second reaction container 30 in the second measuring device 120.

[0204] As an embodiment, when executing each coagulation test item and non-coagulation test item, the sample distribution action is performed first, and then the transfer device 140 transfers the reaction container with the sample loaded from the sample loading position to the corresponding measurement device for measurement. In this way, the setting of the sample distribution device 150 is not affected by the internal structure and position of each measurement device, which is conducive to reducing the movement stroke of the sample needle.

[0205] As an embodiment, the coagulation test items performed by the first measuring device 110 and the non-coagulation test items performed by the second measuring device 120 share the same sample loading position for sample loading. The transfer device 140 transfers the first reaction container 20 and the second reaction container 30 after sample loading from the same sample loading position to the first measuring device 110 and the second measuring device 120, respectively. This helps to reduce the working positions of the transfer device 140 and the sample needle. The sample loading position forms a buffer tray for the reaction container supply device 130. Of course, in specific applications, as an alternative embodiment, the first measuring device 110 and the second measuring device 120 can also be loaded at different sample loading positions, and the transfer device 140 transfers the first reaction container 20 and the second reaction container 30 after sample loading from two sample loading positions to the first measuring device 110 and the second measuring device 120, respectively.

[0206] As an embodiment, each measuring device shares the same sample loading position for sample loading, which helps to reduce the number of sample needle working positions. Of course, in specific applications, the sample loading position of at least one measuring device may be different from that of other measuring devices.

[0207] As an embodiment, the analyzer execution body 100 further includes a reagent dispensing device 160, which is configured to draw reagents from reagent containers and dispense at least a portion of the drawn reagents into reaction containers provided by the reaction container supply device 130. The reagent dispensing device 160 may dispense reagents by: drawing a first type of reagent from a first type of reagent container and dispensing at least a portion of the drawn first type of reagent into the first reaction container 20; and drawing a second type of reagent from a second type of reagent container and dispensing at least a portion of the drawn second type of reagent into the second reaction container 30.

[0208] As an embodiment, the sample analysis device 10 further includes a first identification component 300, which is used to identify the sample container 40 before the sample is aspirated from the sample container 40; the controller 200 is further configured to: obtain at least the test items to be tested of the sample in the sample container 40 based on the feedback information of the first identification component 300.

[0209] As an embodiment, the controller 200 is further configured to control the analyzer execution unit 100 to perform a test on the sample in the sample container 40 based on the test item information of the sample. In this embodiment, the sample analyzer 10 automatically obtains the test item of the sample based on the feedback information from the first identification component 300 and automatically controls the analyzer execution unit 100 to perform the corresponding test item, resulting in a high degree of automation.

[0210] As an embodiment, the controller 200 is further configured to selectively use the reaction vessels provided by the reaction vessel supply device 130 as the first reaction vessel 20 or the second reaction vessel 30 based on the test item of the sample. In this embodiment, the sample's test requirements are obtained based on feedback from the first identification component, and based on the sample's test requirements, a decision is made as to whether the reaction vessels supplied by the reaction vessel supply device 130 are to be used by the first measurement device 110 or the second measurement device 120.

[0211] As an embodiment, the controller 200 selectively uses the reaction container provided by the reaction container supply device 130 as the first reaction container 20 or the second reaction container 30 according to the test item to be tested of the sample, including: when the test item to be tested of the sample includes a coagulation test item, at least one reaction container provided by the reaction container supply device 130 is used as the first reaction container 20, the sample dispensing device 150 is controlled to absorb the sample from the sample container 40, and at least a portion of the absorbed sample is distributed to the first reaction container 20 provided by the reaction container supply device 130; the transfer device 140 is controlled to transfer the first reaction container 20 loaded with the sample to the first measuring device 110, the reagent dispensing device 160 is controlled to absorb the first type of reagent from the reagent container, and at least a portion of the absorbed first type of reagent is distributed to the first reaction container 20 loaded with the sample in the first measuring device 110; and the first measuring device 110 is controlled to measure the first sample made of at least the sample and the first type of reagent in the first reaction container 20. In this embodiment, by optimizing the working sequence of the coagulation test items, the samples and reagents of the coagulation test items do not need to be repacked, which is beneficial to ensuring the efficiency of the coagulation test.

[0212] As an embodiment, the controller 200 selectively uses the reaction container provided by the reaction container supply device 130 as the first reaction container 20 or the second reaction container 30 according to the test item to be tested of the sample, including: when the test item to be tested of the sample includes a non-coagulation test item, at least one reaction container provided by the reaction container supply device 130 is used as the second reaction container 30, the sample dispensing device 150 is controlled to absorb the sample from the sample container 40, and at least part of the absorbed sample is distributed to the second reaction container 30 provided by the reaction container supply device 130; the transfer device 140 is controlled to transfer the second reaction container 30 loaded with the sample to the second measuring device 120, the reagent dispensing device 160 is controlled to absorb the second type of reagent from the reagent container, and at least part of the absorbed second type of reagent is distributed to the second reaction container 30 loaded with the sample in the second measuring device 120; and the second measuring device 120 is controlled to measure the second sample made of at least the sample and the second type of reagent in the second reaction container 30. In this embodiment, by optimizing the working sequence of the non-coagulation detection project, the samples and reagents of the non-coagulation detection project do not need to be repackaged, which is beneficial to ensuring the efficiency of the non-coagulation detection and does not require additional consumption of the first reaction container 20 required for the coagulation detection project.

[0213] As an embodiment, the controller 200 is further configured to parse and obtain the measurement results of the sample based on the feedback information from the first measurement device 110 and / or the second measurement device 120. When the test items to be tested for a sample only include coagulation test items that can be performed by the first measurement device 110, the controller 200 parses and obtains the measurement results of the sample based only on the feedback information from the first measurement device 110; when the test items to be tested for a sample only include non-coagulation test items that can be performed by the second measurement device 120, the controller 200 parses and obtains the measurement results of the sample based only on the feedback information from the second measurement device 120; when the test items to be tested for a sample include both coagulation test items that can be performed by the first measurement device 110 and non-coagulation test items that can be performed by the second measurement device 120, the controller 200 parses and obtains the measurement results of the sample based on the feedback information from the first measurement device 110 and the feedback information from the second measurement device 120.

[0214] In one embodiment, the first recognition component 300 is configured to identify an identification code of the sample container 40. The identification code may include at least one of a QR code, a barcode, and a radio frequency identification (RFID). The controller 200 obtains the test item information of the sample in the sample container 40 based on the identification code identified by the first recognition component 300.

[0215] Of course, in specific applications, as an alternative embodiment, the first identification component 300 can be used to identify the appearance characteristics of the sample container 40 in addition to the identification code of the sample container 40. The appearance characteristics of the sample container 40 include at least one of the shape of the sample container body 40, the size of the sample container body, the sample volume, the presence of a cap, the color of the cap, the shape of the cap, and the size of the cap. Based on the feedback information from the first identification component 300, the controller 200 obtains at least one of the following information in addition to the test item information of the sample: the sample volume in the sample container 40, the type of the sample container 40, the sample number information, and the patient information.

[0216] As an embodiment, the first identification component 300 includes at least one of a visual camera, a barcode scanner, a QR code scanner, and a wireless radio frequency code reader.

[0217] As an embodiment, the reagent dispensing device 160 includes a first reagent dispensing mechanism 161 and a second reagent dispensing mechanism 162; the first reagent dispensing mechanism 161 is used to draw the first type of reagent from the first reagent container and dispense at least part of the drawn first type of reagent into the first reaction container 20, and the second reagent dispensing mechanism 162 is used to draw the second type of reagent from the second reagent container and dispense at least part of the drawn second type of reagent into the second reaction container 30. In this embodiment, the distribution of the first type of reagent in the first reaction container 20 and the distribution of the second type of reagent in the second reaction container 30 are respectively performed by two different reagent dispensing mechanisms. In this way, on the one hand, the distribution of the first type of reagent in the first reaction container 20 and the distribution of the second type of reagent in the second reaction container 30 can be carried out simultaneously, which is beneficial to improving the detection efficiency of the sample; on the other hand, it is beneficial to reduce the movement stroke of the reagent dispensing mechanism. Of course, in specific applications, as an alternative embodiment, the distribution of the first type of reagent in the first reaction container 20 and the distribution of the second type of reagent in the second reaction container 30 can also be performed by the same reagent dispensing mechanism.

[0218] As one embodiment, the first reagent dispensing mechanism 161 is configured to draw the first type of reagent from the first reagent container and dispense at least a portion of the drawn first type of reagent into the first reaction container 20 containing the sample. In this embodiment, the coagulation test performed by the first assay device 110 is performed by first dispensing the sample into the first reaction container 20, and then dispensing the first type of reagent into the first reaction container 20 to which the sample has been dispensed. Of course, in specific applications, as an alternative embodiment, the coagulation test performed by the first assay device 110 may also be performed by first dispensing at least a portion of the first type of reagent into the first reaction container 20, and then dispensing the sample into the first reaction container 20 to which the sample has been dispensed.

[0219] As an embodiment, the second reagent dispensing mechanism 162 is used to draw the second type of reagent from the second reagent container and dispense at least a portion of the drawn second type of reagent into the second reaction container 30 containing the sample. In this embodiment, the non-coagulation test item performed by the second measuring device 120 is to first dispense the sample into the second reaction container 30, and then dispense the second type of reagent into the second reaction container 30 to which the sample has been dispensed. Of course, in a specific application, as an alternative embodiment, the non-coagulation test item performed by the second measuring device 120 may also be to first dispense at least a portion of the second type of reagent into the second reaction container 30, and then dispense the sample into the second reaction container 30 to which the at least partially second type of reagent has been dispensed.

[0220] As an embodiment, the sample analysis device 10 also includes a first reagent tray 170 and a second reagent tray 180. The first reagent tray 170 is used to carry a first reagent container, and the first reagent container is loaded with a first type of reagent for performing coagulation detection items; the second reagent tray 180 is used to carry a second reagent container, and the second reagent container is loaded with a second type of reagent for performing non-coagulation detection items. The first reagent dispensing mechanism 161 is used to draw the first type of reagent from the first reagent container in the first reagent tray 170 and dispense at least part of the drawn first type of reagent into the first reaction container 20. The second reagent dispensing mechanism 162 is used to draw the second type of reagent from the second reagent container in the second reagent tray 180 and dispense at least part of the drawn second type of reagent into the second reaction container 30 loaded with the sample. In this embodiment, the first type of reagent and the second type of reagent are respectively stored in two different reagent trays, so that the first reagent dispensing mechanism 161 and the second reagent dispensing mechanism 162 can simultaneously perform the reagent aspiration action without affecting each other, thereby helping to ensure the detection efficiency of the sample. Of course, in a specific application, as an alternative embodiment, the first type of reagent and the second type of reagent can also be stored in the same reagent tray, that is, the first reagent container and the second reagent container are stored in the same reagent tray.

[0221] In one embodiment, the sample analysis device 10 further includes a second identification component 500, which is used to identify reagent containers. The reagent containers include a first reagent container and a second reagent container, where the first reagent container is loaded with a first type of reagent and the second reagent container is loaded with a second type of reagent. The controller 200 is further configured to obtain at least information about the reagents in the reagent containers based on feedback from the second identification component 500.

[0222] As an embodiment, the first reagent tray 170 is provided with at least one second identification component 500, and the second reagent tray 180 is provided with at least one second identification component 500. The second identification component 500 in the first reagent tray 170 is used to identify the first reagent container of the first reagent tray 170. The second identification component 500 in the second reagent tray 180 is used to identify the first reagent container of the second reagent tray 180. In this embodiment, the second identification components 500 for identifying the first reagent container and the second reagent container are respectively provided in the first reagent tray 170 and the second reagent tray 180; of course, in specific applications, the arrangement of the second identification component 500 is not limited to this. For example, as an alternative embodiment, the second identification component 500 can also be provided on the clamping claw used to load the reagent container on the reagent tray.

[0223] As an embodiment, the controller 200 is further configured to control the reagent dispensing device 160 to draw the first type of reagent from the first reagent container identified by the second identification component 500 and dispense it into the first reaction container 20 .

[0224] As an embodiment, the controller 200 is further configured to control the reagent dispensing device 160 to draw the second type of reagent from the second reagent container identified by the second identification component 500 and dispense it into the second reaction container 30 .

[0225] As an embodiment, the reagent information includes at least one of the following information: the type of reagent, the composition of the reagent, the amount of reagent in the reagent container, the reagent number information, and the type of the reagent container.

[0226] As an embodiment, the first measuring device 110 includes a first incubation mechanism 111 and a first measuring component 112. The first incubation mechanism 111 is used to incubate the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid. The first measuring component 112 is used to measure the coagulation test item on the first sample prepared by at least the second liquid and the first type of reagent in the first reaction container 20. The second measuring device 120 includes a second incubation mechanism 121 and a second measuring component 122. The second incubation mechanism 121 is used to incubate the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid. The second measuring component 122 is used to measure the non-coagulation test item on the second sample prepared by at least the fourth liquid in the second reaction container 30. The second incubation mechanism 121 and the first incubation mechanism 111 are two different incubation mechanisms. In this embodiment, the coagulation test items performed by the first measuring device 110 and the non-coagulation test items of the second measuring device 120 are incubated in two different incubation mechanisms, respectively. Of course, in a specific application, as an alternative embodiment, the coagulation test items performed by the first measuring device 110 and the non-coagulation test items performed by the second measuring device 120 can also share the same incubation mechanism for incubation.

[0227] In one embodiment, the first measuring unit 112 includes at least one first illumination unit 1121 and multiple first light receiving units 1122. The first illumination unit 1121 is configured to emit light toward the first reaction vessel 20 containing the first sample, and the multiple first light receiving units 1122 are configured to receive light information generated after the light is transmitted, reflected, or scattered by the first sample. The first light receiving units 1122 may specifically be photodetectors PD that can perform photoelectric conversion.

[0228] As an embodiment, the first measurement component 112 also includes a first measurement carrying component 1123. The first measurement carrying component 1123 is formed with a plurality of first detection holes, and each first detection hole can accommodate a first reaction container 20 for measurement. The first illumination component 1121 uses light to illuminate the first reaction container 20 loaded with the first sample in the first detection hole, and the light is received by the first light receiving component 1122. The sample is analyzed by analyzing the received light intensity signal. In this embodiment, the first measurement carrying component 1123 and the first incubation mechanism 111 are set independently of each other; of course, in specific applications, as an alternative embodiment, the first measurement carrying component 1123 and the first incubation mechanism 111 can also be integrated into one.

[0229] As an embodiment, the coagulation detection items performed by the first measuring device 110 are classified according to whether a diluent needs to be added, and include dilute coagulation detection items that require the addition of a diluent and undiluted coagulation detection items that do not require the addition of a diluent. According to the different types of added reagents, the coagulation detection items performed by the first measuring device 110 include multi-reagent coagulation detection items and single-reagent coagulation detection items. The multi-reagent coagulation detection items require the injection of a trigger reagent and a mixed reagent into the first reaction container 20 loaded with the sample respectively; the single-reagent coagulation detection item requires the injection of a trigger reagent into the first reaction container 20 loaded with the sample, but does not require the injection of a mixed reagent. It should be noted that the multi-reagent coagulation detection item can be a dilute coagulation detection item or a undiluted coagulation detection item, that is, the first specimen of the multi-reagent coagulation detection item can be made of a sample, a mixed reagent, and a trigger reagent, or can be made of a sample, a mixed reagent, a trigger reagent, and a diluent. The single-reagent coagulation test item can be a diluted coagulation test item or an undiluted coagulation test item, that is, the sample of the single-reagent coagulation test item can be made of a sample and a trigger reagent, or can be made of a sample, a trigger reagent, and a diluent. Of course, in specific applications, the coagulation test items that can be performed by the first measurement device 110 are not limited to this. For example, as an alternative embodiment, the sample test items that can be performed by the first measurement device 110 can only include one of the diluted coagulation test items and the undiluted coagulation test items, or the sample test items that can be performed by the first measurement device 110 can only include one of the multi-reagent coagulation test items and the single-reagent coagulation test items.

[0230] As an embodiment, the first reagent dispensing mechanism 161 includes a mixed reagent dispensing mechanism 1611 and a trigger reagent dispensing mechanism 1612. The mixed reagent dispensing mechanism 1611 is used to draw the mixed reagent from the mixed reagent container and distribute it to the first reaction container 20, and the trigger reagent dispensing mechanism 1612 is used to draw the trigger reagent from the trigger reagent container and distribute it to the first reaction container 20. The mixed reagent dispensing mechanism 1611 and the trigger reagent dispensing mechanism 1612 are set independently of each other, and the mixed reagent dispensing mechanism 1611 and the trigger reagent dispensing mechanism 1612 can work in parallel, so that the mixed reagent dispensing operation of one first reaction container 20 can be performed simultaneously with the trigger reagent dispensing operation of another first reaction container 20. Of course, in specific applications, as an alternative embodiment, the mixed reagent dispensing operation and the trigger reagent dispensing operation can also be performed by the same reagent dispensing mechanism.

[0231] As one embodiment, the mixed reagent dispensing mechanism 1611 includes a mixed reagent needle, a second aspiration / discharge drive component for driving the mixed reagent needle to aspirate and discharge the mixed reagent, and a second motion drive component for driving the mixed reagent needle to move in space. The trigger reagent dispensing mechanism 1612 includes a trigger reagent needle, a third aspiration / discharge drive component for driving the trigger reagent needle to aspirate and discharge the trigger reagent, and a third motion drive component for driving the trigger reagent needle to move in space.

[0232] As an embodiment, the diluent used in the coagulation test item can be stored in the first reagent disk 170 through a diluent container, and can also be stored outside the first reagent disk 170 through a diluent container.

[0233] As an embodiment, the diluent used in the coagulation test item can be sucked from the diluent container by the first reagent dispensing mechanism 161 and dispensed into the first reaction container 20, or can be sucked from the diluent container by the sample dispensing device 150 and dispensed into the first reaction container 20, or can be sucked from the diluent container by a diluent dispensing device independent of the first reagent dispensing mechanism 161 and the sample dispensing device 150 and dispensed into the first reaction container 20.

[0234] As an embodiment, each coagulation test item includes at least a sample addition period, an incubation period, a trigger reagent period, and a measurement period, which are performed in sequence. During the sample addition period, the controller 200 controls the analyzer execution body 100 to complete the sample addition operation. During the incubation period, the controller 200 controls the analyzer execution body 100 to complete the incubation operation. During the trigger reagent period, the controller 200 controls the analyzer execution body 100 to complete the trigger reagent addition operation. During the measurement period, the controller 200 controls the analyzer execution body 100 to complete the measurement operation.

[0235] As an embodiment, during the sample addition period of the coagulation test item, the controller 200 controls the sample dispensing device 150 to draw the sample from the sample container 40 and distribute it to the first reaction container 20 to complete the sample addition operation. During the incubation period of the multi-reagent coagulation test item, the controller 200 controls the first reagent dispensing mechanism 161 to draw the mixed reagent from the reagent container and distribute it to the first reaction container 20, and controls the first incubation mechanism 111 to incubate the first reaction container 20 loaded with at least the sample and the mixed reagent to complete the incubation operation of the multi-reagent coagulation test item. During the incubation period of the single-reagent coagulation test item, the controller 200 controls the first incubation mechanism 111 to incubate the first reaction container 20 loaded with at least the sample to complete the incubation operation of the single-reagent coagulation test item. During the trigger reagent period, the controller 200 controls the first reagent dispensing mechanism 161 to draw the trigger reagent from the reagent container and distribute it to the first reaction container 20, and performs a mixing operation on the first reaction container 20 to complete the trigger reagent addition operation. During the measurement period, the controller 200 controls the first measurement component 112 to measure the first sample in the first reaction container 20 to complete the measurement operation.

[0236] In one embodiment, each coagulation test item includes a cup-discarding period after the measurement period. Specifically, each coagulation test item includes a sample addition period, an incubation period, a triggering reagent period, a measurement period, and a cup-discarding period, which are performed in sequence. During the cup-discarding period, the controller 200 controls the analyzer execution unit 100 to discard the first reaction container 20 after the measurement is completed.

[0237] In one embodiment, the first measurement device 110 also includes a first recovery container. During the cup discarding period of the coagulation test, the controller 200 controls the transfer device 140 to discard the first reaction container 20 after measurement from the first measurement component 112 to the first recovery container. The first recovery container allows an operator or a robot to remove the first reaction container 20. In this embodiment, the transfer device 140 is used to discard the first reaction container 20; however, in specific applications, as an alternative embodiment, the first reaction container 20 after measurement can also be discarded to the first recovery container by other mechanisms independent of the transfer device 140.

[0238] In one embodiment, the first assay device 110 uses at least one of a coagulation assay, an immunoturbidimetric assay, and a chromogenic substrate assay to perform a coagulation assay on a first sample prepared from at least a sample and a first-class reagent. The coagulation assay process includes adding a sample and a first-class reagent (possibly one or more reagents) to a first reaction vessel 20, mixing and incubating the sample and first-class reagent mixture to prepare the first sample. The first reaction vessel 20 containing the first sample is then illuminated by light emitted by a first illumination component 1121, which is then received by a first light receiving component 1122 (e.g., a detector PD). The received optical signal (e.g., light intensity) is analyzed to complete the analysis of the first sample.

[0239] As an embodiment, the first measuring device 110 can perform coagulation test items including, but not limited to, plasma prothrombin test (PT), activated partial thromboplastin test (APTT), fibrinogen test (FIB), thrombin test (TT), and antithrombin III test (ATIII). The activated partial thromboplastin test (APTT) is a multi-reagent test item, and during the incubation process, mixed reagents need to be added to prepare the sample.

[0240] As an embodiment, the non-coagulation test items measured by the second measuring device 120 are immunoassay items. The second measuring device 120 can use chemiluminescence to measure molecular markers in the sample. In clinical tests related to coagulation, in addition to using coagulation methods, immunoturbidimetry, and chromogenic substrate methods to measure routine coagulation test items, sometimes it is necessary to assist with the measurement of some molecular markers, such as the measurement of four thrombosis items (thrombin-antithrombin complex TAT, plasmin-antiplasmin complex PIC, tissue plasminogen activator-plasminogen activator inhibitor complex tPAI.C, thrombomodulin TM). In this embodiment, the first measuring device 110 can perform the measurement of routine coagulation test items, and the second measuring device 120 can perform the measurement of molecular markers. Therefore, using the sample analysis device 10 provided in this embodiment, various clinical test requirements related to coagulation can be met on a single machine, without the need for two analysis devices. The operation is simple, and only one sample container 40 needs to be drawn from the patient. Specifically, since the non-coagulation test items measured by the second measuring device 120 are immunoassay items, if molecular markers need to be measured in conjunction with coagulation-related clinical tests, the sample analysis device 10 of this embodiment can be used alone to measure both the coagulation test items and the molecular markers. This simplifies the molecular marker measurement process in coagulation-related clinical tests and eliminates the need to collect samples from the patient in two sample containers 40, effectively reducing sample usage. Of course, in specific applications, the non-coagulation test items measured by the second measuring device 120 can also be other test items, such as biochemical test items, erythrocyte sedimentation rate test items, etc.

[0241] As an embodiment, the second measuring component 122 includes a second light receiving component 1221, which can be a photomultiplier tube. The second measuring device 120 uses chemiluminescence to perform an immunoassay on a second sample prepared from at least a sample and a second type of reagent. The main process of the immunoassay includes: adding the sample and the second type of reagent to the second reaction container 30, and mixing and incubating the mixture of the added sample and the second type of reagent to prepare the sample; in addition to adding the sample and the second type of reagent and the corresponding mixing and incubation, the immunoassay also includes a magnetic separation step to prepare the second sample. Finally, during the measurement, the self-luminous second sample is photon counted by a PMT (i.e., a photomultiplier tube) to complete the analysis of the second sample.

[0242] As an embodiment, the second measurement component 122 further includes a second measurement support component 1222 having a plurality of second detection wells, each of which can accommodate a second reaction vessel 30 for measurement. During immunoassay, a photomultiplier tube counts the photons of the analyte self-luminescing within the second reaction vessel 30 in the second detection well to complete the immunoassay of the sample.

[0243] In one embodiment, the second incubation mechanism 121 and the second measurement component 122 are integrated into an incubation and measurement tray. Specifically, the second incubation mechanism 121 and the second measurement component 122 are integrated. The outer ring of the incubation and measurement tray serves as the second measurement support component 1222, and the outer ring of the incubation and measurement tray serves as the second incubation mechanism 121. This makes the structure of the second measurement device 120 relatively compact, facilitating the miniaturization of the sample analysis device 10. Of course, in specific applications, as an alternative embodiment, the second measurement support component 1222 and the second incubation mechanism 121 can also be provided separately and independently.

[0244] As an embodiment, the second assay device 120 further includes a magnetic separation mechanism 123, which is configured to perform a magnetic separation operation on a reaction solution composed of at least the sample and the second type of reagent. The sample detection device 300 is configured to perform an assay on the second sample produced after the magnetic separation operation. The magnetic separation mechanism 123 is configured to magnetically adsorb the reaction solution in the second reaction vessel 30, thereby separating the reaction solution into a magnetic bead solution and a clear solution. After the reaction solution is processed by the magnetic separation mechanism 123, the clear solution is disposed of as waste, and the magnetic bead solution is used to prepare a second sample for subsequent sample detection.

[0245] As an embodiment, during the magnetic separation operation, a separation liquid is required to perform magnetic separation and cleaning on the reaction liquid in the second reaction container 30. The magnetic separation and cleaning is mainly used to clean impurities in the reaction liquid while retaining the portion to be tested, thereby purifying the reaction liquid.

[0246] As an embodiment, the second reagent dispensing mechanism 162 includes a first reagent needle, a fourth aspiration and discharge driving component for driving the first reagent needle to aspirate and discharge the mixed reagent, and a fourth motion driving component for driving the first reagent needle to perform spatial motion.

[0247] As an embodiment, the second measuring device 120 also includes a second recovery container. After the sample completes the determination of the immunoassay item in the second measuring component 122, the controller 200 controls the transfer device 140 to discard the second reaction container 30 that has completed the determination from the second measuring component 122 to the second recovery container. The second recovery container can be used for an operator or a robot to take away the second reaction container 30. The second recovery container and the first recovery container can be the same container or two different containers. In this embodiment, the transfer device 140 is used to perform the operation of discarding the second reaction container 30; of course, in a specific application, as an alternative embodiment, the second reaction container 30 that has completed the determination can also be discarded to the second recovery container by other mechanisms independent of the transfer device 140.

[0248] As an embodiment, the immunoassay items include diluted immunoassay items that require the addition of a diluent and undiluted immunoassay items that do not require the addition of a diluent. The diluent used in the immunoassay items can be drawn from the diluent container by the second reagent dispensing mechanism 162 and dispensed into the second reaction container 30, can also be drawn from the diluent container by the sample dispensing device 150 and dispensed into the second reaction container 30, or can be drawn from the diluent container by a diluent dispensing device independent of the second reagent dispensing mechanism 162 and the sample dispensing device 150 and dispensed into the second reaction container 30.

[0249] As an embodiment, the execution process of the immunoassay project (taking the non-dilution immunoassay project as an example) includes: the sample distribution device 150 draws the sample from the sample container 40 and distributes it to the second reaction container 30, the transfer device 140 transfers the second reaction container 30 after the sample is loaded from the sample loading position to the second incubation mechanism 121, the second reagent dispensing mechanism 162 draws the second type of reagent from the reagent container and distributes it to the second reaction container 30, the second incubation mechanism 121 incubates the sample in the second reaction container 30 with the second type of reagent, the transfer device 140 transfers the incubated second reaction container 30 from the second incubation mechanism 121 to the magnetic separation mechanism 123 for magnetic separation operation, and the magnetic separation device transfers the second reaction container 30 after magnetic separation to the second measurement component 122 for measurement of the immunoassay project.

[0250] As an embodiment, the controller 200 is further configured to: control the transfer device 140 to transfer the first reaction container 20, which has been provided by the reaction container supply device 130 and has had its sample dispensed by the sample dispensing device 150, from outside the second measuring device 120 to the first measuring device 110; and control the transfer device 140 to transfer the second reaction container 30, which has been provided by the reaction container supply device 130 and has had its sample dispensed by the sample dispensing device 150, from outside the first measuring device 110 to the second measuring device 120. In this embodiment, samples for coagulation testing do not need to be transferred to the second measuring device 120, and samples for coagulation testing do not need to be transferred to the first measuring device 110, and there is no need for secondary packaging of the samples, thereby fully ensuring the detection efficiency of each sample detection item.

[0251] In one embodiment, the controller 200 is configured to control the transfer device 140 to transfer a first reaction container 20 loaded with a sample for use in coagulation testing from the reaction container supply device 130 to the first transfer area 101, and to control the transfer device 140 to transfer the first reaction container 20 from the first transfer area 101 to the first incubation mechanism 111. The controller 200 is further configured to control the transfer device 140 to transfer a second reaction container 30 loaded with a sample for use in non-coagulation testing from the reaction container supply device 130 to the first transfer area 101, and to control the transfer device 140 to transfer the second reaction container 30 from the first transfer area 101 to the second incubation mechanism 121. In this embodiment, after the first and second reaction containers 20 and 30 are loaded, they are first transferred from the sample loading position to the same transfer area for transfer, and then transferred from the transfer area to the first incubation mechanism 111 and the second incubation mechanism 121, respectively. This helps to simplify the motion trajectory of a single transfer action of the transfer device 140. Of course, in specific applications, as an alternative embodiment, at least one of the first reaction container 20 and the second reaction container 30 can also be directly transferred from the sample loading position to the corresponding incubation mechanism after the sample loading is completed, without having to be transferred to the transfer area for transfer first.

[0252] As an embodiment, the first transfer area 101 is located outside the first measuring device 110 and outside the second measuring device 120 .

[0253] As an embodiment, the first transfer area 101 includes a first transfer position 1011, a second transfer position 1012 and a third transfer position 1013. The first transfer position 1011, the second transfer position 1012 and the third transfer position 1013 are three different positions. The first transfer position 1011 is the position where the transfer device 140 transfers the first reaction container 20 and the second reaction container 30 after the sample is added to the first transfer area 101, that is, the first transfer position 1011 is the position where the transfer device 140 places the first reaction container 20 and the second reaction container 30 in the first transfer area 101. The second transfer position 1012 is the position where the transfer device 140 takes the first reaction container 20 from the first transfer area 101 to transfer it toward the first incubation mechanism 111, that is, the second transfer position 1012 is the position where the transfer device 140 takes the first reaction container 20 from the first transfer area 101. The third transfer position 1013 is the position where the transfer device 140 takes the second reaction container 30 from the first transfer area 101 to transfer it toward the second incubation mechanism 121, that is, the third transfer position 1013 is the position where the transfer device 140 takes the second reaction container 30 from the first transfer area 101.

[0254] As an embodiment, the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample for coagulation test from the reaction container supply device 130 to the first transfer position 1011, control the transfer device 140 to transfer the first reaction container 20 from the first transfer position 1011 to the second transfer position 1012, and control the transfer device 140 to transfer the first reaction container 20 from the second transfer position 1012 to the first incubation mechanism 111. When a sample needs to be measured for a coagulation test in the first measurement device 110, the sample distribution device 150 first distributes the sample to the first reaction container 20, and then the transfer device 140 transfers the first reaction container 20 after the sample is loaded to the first transfer position 1011, the second transfer position 1012, and the first incubation mechanism 111 in sequence.

[0255] As an embodiment, the controller 200 is further configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample for non-coagulation test items from the reaction container supply device 130 to the first transfer position 1011, control the transfer device 140 to transfer the second reaction container 30 from the first transfer position 1011 to the third transfer position 1013, and control the transfer device 140 to transfer the second reaction container 30 from the third transfer position 1013 to the second incubation mechanism 121. When a sample needs to be measured for a non-coagulation test item in the second measuring device 120, the sample dispensing device 150 first distributes the sample to the second reaction container 30, and then the transfer device 140 transfers the loaded second reaction container 30 to the first transfer position 1011, the third transfer position 1013, and the second incubation mechanism 121 in sequence.

[0256] As one embodiment, the transfer device 140 includes a first transfer mechanism 141, a second transfer mechanism 142, and a third transfer mechanism 143. The first transfer mechanism 141 is primarily used to transfer reaction vessels between the sample loading station and the first transfer area 101. That is, the first transfer mechanism 141 is used to transfer the reaction vessels (including the first reaction vessel 20 and the second reaction vessel 30) after sample loading from the sample loading station to the first transfer area 101. The second transfer mechanism 142 is primarily used to transfer reaction vessels between the first transfer area 101 and the first assay device 110. That is, the second transfer mechanism 142 is used to transfer the first reaction vessel 20 after sample loading from the first transfer area 101 to the first assay device 110. The third transfer mechanism 143 is primarily used to transfer reaction vessels between the first transfer area 101 and the second assay device 120. That is, the second transfer mechanism 142 is used to transfer the second reaction vessel 30 after sample loading from the first transfer area 101 to the second assay device 120. The first transfer mechanism 141, the second transfer mechanism 142, and the third transfer mechanism 143 are three independently operable transfer mechanisms. In this embodiment, the transfer of reaction vessels between the sample loading station and the first transfer area 101, the transfer of reaction vessels between the first transfer area 101 and the first assay device 110, and the transfer of reaction vessels between the first transfer area 101 and the second assay device 120 are each performed using three different transfer mechanisms. This allows for simultaneous transfer of reaction vessels in different areas, improving reaction vessel transfer efficiency. Furthermore, it simplifies the motion trajectory of a single transfer mechanism and reduces its travel range, thereby reducing the design complexity of the transfer mechanism 140. Of course, in specific applications, as an alternative implementation scheme, at least two transfer actions of the transfer of reaction containers between the sample loading position and the first transfer area 101, the transfer of reaction containers between the first transfer area 101 and the first measuring device 110, and the transfer of reaction containers between the first transfer area 101 and the second measuring device 120 can also be performed by the same transfer mechanism, that is, at least two of the first transfer mechanism 141, the second transfer mechanism 142 and the third transfer mechanism 143 can also be the same transfer mechanism.

[0257] As an embodiment, the first transfer mechanism 141 is used to transfer the first reaction container 20 loaded with the sample from the reaction container supply device 130 to the first transfer area 101 under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the first transfer area 101 under the control of the controller 200; the second transfer mechanism 142 is used to transfer the first reaction container 20 located in the first transfer area 101 and used for performing coagulation detection item determination to the first incubation mechanism 111 under the control of the controller 200; the third transfer mechanism 143 is used to transfer the second reaction container 30 located in the first transfer area 101 and used for performing non-coagulation detection item determination to the second incubation mechanism 121 under the control of the controller 200.

[0258] As an embodiment, the third transfer mechanism 143 is time-shared and multiplexed to implement the following operations: transferring the second reaction container 30 loaded with the sample to be tested from the third intermediate transfer position 1013 to the second incubation mechanism 121; transferring the incubated second reaction container 30 from the second incubation mechanism 121 to the magnetic separation mechanism 123; transferring the magnetically separated second reaction container 30 to the second measurement carrier 1222 for measurement; and transferring the second reaction container 30 after the measurement to the second cup discarding position for discarding. Of course, in specific applications, the third transfer mechanism 143 can also be decomposed into at least two independent transfer sub-mechanisms to respectively implement transfer operations in different areas of the third transfer mechanism 143, such as one sub-transfer mechanism is used to transfer the second reaction container 30 between the third intermediate transfer position 1013 and the second incubation mechanism 121, and the other sub-transfer mechanism is used to transfer the second reaction container 30 between the second incubation mechanism 121, the magnetic separation mechanism 123, the second measurement carrier 1222, and the second cup discarding position.

[0259] As an embodiment, the transfer device 140 further includes a fourth transfer mechanism 144, the first transfer mechanism 141 is used to transfer the reaction container loaded with the sample from the first reaction container 20 supply device to the first transfer position 1011 under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the first transfer position 1011 under the control of the controller 200; the fourth transfer mechanism 144 is used to transfer the first reaction container located at the first transfer position 1011 and used for performing coagulation test items under the control of the controller 200. The container 20 is transferred to the second intermediate transfer position 1012, and is used to transfer the second reaction container 30 located at the first intermediate transfer position 1011 and used for non-coagulation test items to the third intermediate transfer position 1013 under the control of the controller 200. The second transfer mechanism 142 is used to transfer the first reaction container 20 located at the second intermediate transfer position 1012 to the first incubation mechanism 111 under the control of the controller 200. The third transfer mechanism 143 is used to transfer the second reaction container 30 located at the third intermediate transfer position 1013 to the second incubation mechanism 121 under the control of the controller 200. The first transfer mechanism 141, the second transfer mechanism 142, the third transfer mechanism 143, and the fourth transfer mechanism 144 are four independent transfer mechanisms. In this embodiment, the transfer of reaction containers between the first intermediate transfer position 1011 and the second intermediate transfer position 1012, and the transfer of reaction containers between the first intermediate transfer position 1011 and the third intermediate transfer position 1013 are performed by the same transfer mechanism (i.e., the fourth transfer mechanism 144), and the transfer mechanism is independent of the first transfer mechanism 141, the second transfer mechanism 142, and the third transfer mechanism 143, which facilitates the transfer of reaction containers between the first intermediate transfer position 1011 and the second intermediate transfer position 1012, and the transfer of reaction containers between the sample loading position and the first transfer area 101, the transfer of reaction containers between the first transfer area 101 and the first measuring device 110, and the transfer of reaction containers between the first transfer area 101 and the second measuring device 120. These can be carried out synchronously, which is conducive to further improving the transfer efficiency of the reaction containers, simplifying the motion trajectory of the single transfer mechanism, and reducing the motion stroke of the single transfer mechanism.

[0260] As an embodiment, the first transfer mechanism 141 includes a first gripper and a first drive assembly. The first gripper is used to grip and release the first reaction container 20, and to grip and release the second reaction container 30. The first drive assembly is used to drive the first gripper to perform two-dimensional or three-dimensional spatial motion, so as to drive the first gripper to grip the first reaction container 20 loaded with the sample from the reaction container supply device 130 to the first transfer area 101 under the control of the controller 200, and to drive the first gripper to grip the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the first transfer area 101 under the control of the controller 200. In this embodiment, the first transfer mechanism 141 is a gripper-type conveying mechanism (or manipulator). The first transfer mechanism 141 can be mounted above the sample loading position and the first transfer position 1011, which facilitates the layered arrangement of the sample analysis device 10. Of course, in specific applications, the configuration of the first transfer mechanism 141 is not limited to this. For example, as an alternative embodiment, the first transfer mechanism 141 can also be a turntable-type conveying mechanism or a track-type conveying mechanism.

[0261] As an embodiment, the second transfer mechanism 142 includes a second clamping claw and a second drive assembly, and the second clamping claw is used to clamp and release the first reaction container 20. The second drive assembly is used to drive the second clamping claw to perform two-dimensional or three-dimensional spatial movement, so as to drive the second clamping claw to clamp the first reaction container 20 loaded with the sample and transfer it from the first transfer area 101 to the first measuring device 110 under the control of the controller 200. In this embodiment, the second transfer mechanism 142 is a clamping claw conveying mechanism (or manipulator), and the second transfer mechanism 142 can be set up above the second transfer position 1012 and the first measuring device 110, which is conducive to the layered arrangement of the sample analysis device 10. Of course, in specific applications, the setting method of the second transfer mechanism 142 is not limited to this.

[0262] As an embodiment, the third transfer mechanism 143 includes a third clamp and a third drive assembly, and the third clamp is used to clamp and release the second reaction container 30. The third drive assembly is used to drive the third clamp to perform two-dimensional or three-dimensional spatial movement, so as to drive the third clamp to clamp the second reaction container 30 loaded with the sample and transfer it from the first transfer area 101 to the second measurement device 120 under the control of the controller 200. In this embodiment, the third transfer mechanism 143 is a clamping-type conveying mechanism (or manipulator), and the third transfer mechanism 143 can be set up above the third transfer position 1013 and the second measurement device 120, which is conducive to the layered arrangement of the sample analysis device 10. Of course, in specific applications, the arrangement of the third transfer mechanism 143 is not limited to this.

[0263] In one embodiment, the first, second, and third jaws are identical in shape and size. Specifically, the first, second, and third jaws are identical and can be manufactured using the same processing equipment and techniques. The first, second, and third jaws are interchangeable. In this embodiment, identical first, second, and third jaws reduce the number of materials required for sample analyzer 10, facilitating both manufacturing and future maintenance of sample analyzer 10.

[0264] As one embodiment, the fourth transfer mechanism 144 is a track-type conveyor mechanism. In this embodiment, a track-type mechanism is used to transfer the first reaction container 20 and the second reaction container 30 in the first transfer area 101. Under the premise that the first transfer mechanism 141, the second transfer mechanism 142, and the third transfer mechanism 143 all adopt a gripper-type conveyor mechanism, the fourth transfer mechanism 144 can be arranged in layers with the first transfer mechanism 141, the second transfer mechanism 142, and the third transfer mechanism 143, and the operation of the fourth transfer mechanism 144 can be synchronized with the operation of the first transfer mechanism 141, the second transfer mechanism 142, and the third transfer mechanism 143. Of course, in specific applications, the arrangement of the fourth transfer mechanism 144 is not limited to this. For example, as an alternative embodiment, the fourth transfer mechanism 144 can also be a turntable-type conveyor mechanism or a gripper-type conveyor mechanism.

[0265] As an embodiment, the fourth transfer mechanism 144 includes a transfer track and a first power mechanism for driving the transfer track. The transfer track can carry the first reaction vessel 20 and the second reaction vessel 30 for movement under the drive of the power mechanism. In this embodiment, the reaction vessels are moved by the transfer track. Of course, in a specific application, as an alternative embodiment, the fourth transfer mechanism 144 may also include a stationary track and a second power mechanism for driving the reaction vessels to move along the track. The second power mechanism may include a push rod or a pusher claw for pushing the reaction vessels to move, or may include a mobile cart for carrying the reaction vessels for movement.

[0266] As an embodiment, the transmission track is a transmission belt, which has a simple structure and low cost. Of course, in specific applications, the setting mode of the transmission track is not limited to this. For example, as an alternative embodiment, the transmission track can also be a transmission chain or a transmission roller or a transmission roller.

[0267] As an embodiment, the first intermediate transfer position 1011, the second intermediate transfer position 1012, and the third intermediate transfer position 1013 are distributed along a straight track. In this way, the transfer track of the fourth transfer mechanism 144 can be arranged along a straight line, which helps to reduce the design difficulty of the transfer track of the fourth transfer mechanism 144. Of course, in specific applications, the distribution tracks of the first intermediate transfer position 1011, the second intermediate transfer position 1012, and the third intermediate transfer position 1013 can also be other forms, such as arc tracks or other curved tracks.

[0268] In one embodiment, the first transfer position 1011, the second transfer position 1012, and the third transfer position 1013 are sequentially arranged along a straight line, that is, the second transfer position 1012 is located along the transfer track between the first transfer position 1011 and the third transfer position 1013. In this embodiment, the second transfer position 1012 and the third transfer position 1013 are located on the same side of the first transfer position 1011, and the distance from the second transfer position 1012 to the first transfer position 1011 is shorter than the distance from the third transfer position 1013 to the first transfer position 1011. This allows the transfer track to only have a one-way transfer function, and improves the transfer efficiency of the first reaction container 20 for the coagulation test project. Of course, in specific applications, the distribution of the first transfer position 1011, the second transfer position 1012 and the third transfer position 1013 is not limited to this. For example, as an alternative embodiment, the second transfer position 1012 and the third transfer position 1013 can also be distributed on both sides of the first transfer position 1011 respectively; or, when the second transfer position 1012 and the third transfer position 1013 are located on the same side of the first transfer position 1011, the distance from the second transfer position 1012 to the first transfer position 1011 can also be greater than or equal to the distance from the third transfer position 1013 to the first transfer position 1011.

[0269] As one embodiment, the transfer device 140 also includes a ninth transfer mechanism 145. The second transfer mechanism 142 is time-replicated to perform the following operations: transferring the first reaction container 20 loaded with the sample to be tested from the second intermediate transfer station 1012 to the first incubation mechanism 111; transferring the first reaction container 20, after incubation, from the first incubation mechanism 111 to the buffer station. Furthermore, the second transfer mechanism 142 can also be used to drive the first reaction container 20 to move between different stations in the first incubation mechanism 111. The ninth transfer mechanism 145 is time-replicated to perform the following operations: transferring the first reaction container 20 loaded with the sample to be tested from the buffer station to the trigger reagent addition station; driving the first reaction container 20, after the trigger reagent is added, to swing and / or vibrate to mix the liquid in the first reaction container 20 to produce the first sample; transferring the first reaction container 20 loaded with the first sample from the trigger reagent addition station to the first measurement unit 112; and transferring the first reaction container 20, after measurement, from the first measurement unit 112 to the first cupping station for cupping. In this embodiment, the ninth transfer mechanism 145 is provided to cooperate with the second transfer mechanism 142 to complete the transfer operation of the first reaction container 20 from the first incubation mechanism 111 to the first measurement component 112. This helps to relieve the workload of the second transfer mechanism 142 and reduce the movement range of the second transfer mechanism 142, thereby improving the transfer efficiency of the first reaction container 20. Of course, in specific applications, as an alternative embodiment, the ninth transfer mechanism 145 can also be omitted, and the transfer work of the ninth transfer mechanism 145 can be completed by the second transfer mechanism 142.

[0270] As an embodiment, the ninth transfer mechanism 145 is a gripper-type transfer mechanism.

[0271] As an embodiment, the sample analysis device 10 also includes a sample injection device 190 (also known as an automatic sample injector or a sample scheduling device). The sample injection device 190 is at least used to realize the loading and recovery of the sample container 40. The sample injection device 190 includes a loading area 191, a recovery area 192 and a scheduling mechanism 193. The sample container 40 loaded with the sample to be tested can be placed in the loading area 191 of the sample injection device 190 by an operator or an operating robot to realize the loading of the sample. The scheduling mechanism 193 can dispatch the sample container 40 placed in the loading area 191 to the sample aspiration position for the sample distribution device 150 to aspirate the sample. The sample container 40 after the sample aspiration is completed can be dispatched by the scheduling mechanism 193 to the recovery area 192 for the operator or the operating robot to take away and recover. The loading area 191 and the recovery area 192 can be set separately and independently of each other, or they can be set as an integrated whole. The setting of the sample injection device 190 is mainly used to realize the automatic scheduling of the sample container 40.

[0272] In one embodiment, sample containers 40 are loaded, dispatched, and recovered via a sample rack 50. Specifically, an operator or an operating robot places a sample rack 50 loaded with at least one sample container 40 in the loading area 191 of the sample injection device 190. The sample injection device 190 then dispatches the sample rack 50 placed in the loading area 191 to the sample aspiration position for sample aspiration. The sample injection device 190 then dispatches the sample rack 50, after sample aspiration, to the recovery area 192. Using a sample rack 50 to carry sample containers 40 for loading, dispatching, and recovery not only facilitates the sample analysis device 10's adaptability to sample containers 40 of varying specifications but also facilitates batch loading and recovery of samples. Furthermore, it eliminates the need for operators to touch the sample containers 40, thereby reducing the risk of infection.

[0273] As an embodiment, the sample feeding device 190 is also used to implement caching of the sample container 40. The sample feeding device 190 also includes a cache area, and the scheduling mechanism 193 is further used to: schedule the sample rack 50 to be tested to the cache area to queue for sample aspiration, schedule the sample rack 50 to be tested from the cache area to the sample aspiration position for sample aspiration, schedule the sample rack 50 that needs to be retested to the cache area to wait for re-sample aspiration and testing, and schedule the sample rack 50 that needs to be retested to the sample aspiration position for sample aspiration. The cache area can be independently provided from the loading area 191 and the recovery area 192, or it can be integrated with the loading area 191 and / or the recovery area 192.

[0274] As an embodiment, the sample analysis device 10 further includes a human-computer interaction device 400 , and the human-computer interaction device 400 includes at least one of a display screen, a keyboard, and a mouse.

[0275] As an embodiment, as an embodiment, the analyzer execution body 100 further includes a first cleaning device, and the first cleaning device is used to clean the sample needle.

[0276] This embodiment also provides a sample analysis method, which includes a coagulation measurement step and a non-coagulation measurement step. The coagulation measurement step includes the following steps:

[0277] Controlling the reaction container supply device 130 to provide the first reaction container 20;

[0278] Controlling the sample dispensing device 150 to absorb the sample from the sample container 40 and dispensing at least a portion of the absorbed sample into the first reaction container 20 ;

[0279] Controlling the reagent dispensing device 160 to absorb the first type of reagent from the first reagent container, and dispensing at least a portion of the absorbed first type of reagent into the first reaction container 20;

[0280] Controlling the first measuring device 110 to measure a coagulation test item on a first sample prepared by at least a sample and a first type of reagent in the first reaction container 20;

[0281] The non-coagulation assay procedure includes the following steps:

[0282] Controlling the reaction container supply device 130 to provide the second reaction container 30;

[0283] Controlling the sample dispensing device 150 to absorb the sample from the sample container 40 and dispensing at least a portion of the absorbed sample into the second reaction container 30 ;

[0284] Controlling the reagent dispensing device 160 to absorb the second type of reagent from the second reagent container, and dispensing at least part of the absorbed second type of reagent into the second reaction container 30;

[0285] Controlling the second measuring device 120 to measure a non-coagulation test item on a second sample prepared from at least the sample and the second type of reagent in the second reaction container 30;

[0286] Any reaction container provided by the reaction container supply device 130 can be selectively used as the first reaction container 20 or the second reaction container 30 .

[0287] As an embodiment, the first reaction container 20 and the second reaction container 30 are reaction containers provided by the same reaction container supply device 130 .

[0288] As an embodiment, the coagulation measurement step further includes the step of controlling the transfer device 140 to transfer the first reaction container 20 provided by the reaction container supply device 130 and to which the sample has been allocated by the sample dispensing device 150, after the sample dispensing device 150 is controlled to draw the sample from the sample container 40 and to distribute at least a portion of the drawn sample to the first reaction container 20, and before the reagent dispensing device 160 is controlled to draw the first type of reagent from the first reagent container and to distribute at least a portion of the drawn first type of reagent to the first reaction container 20, to the first measurement device 110.

[0289] As an embodiment, the non-coagulation measurement step further includes the step of controlling the transfer device 140 to transfer the second reaction container 30, which is provided by the reaction container supply device 130 and to which the sample distribution device 150 has distributed the sample, to the second measurement device 120, after the sample distribution device 150 is controlled to draw the sample from the sample container 40 and distribute at least part of the drawn sample to the second reaction container 30, and before the reagent distribution device 160 is controlled to draw the second type of reagent from the second reagent container and distribute at least part of the drawn second type of reagent to the second reaction container 30.

[0290] As an embodiment, the sample analysis method further includes an identification step before the coagulation determination step and / or the non-coagulation determination step, and the identification step includes: controlling the first identification component 300 to identify the sample container 40; obtaining at least the test item information of the sample in the sample container 40 based on the feedback information of the first identification component 300; when the test items to be tested of the sample include coagulation test items, executing the coagulation determination step; when the test items to be tested of the sample include non-coagulation test items, executing the non-coagulation determination step.

[0291] The specific principles and implementation of the sample analysis method provided in this embodiment are similar to those described in the above-mentioned sample analysis device 10 and will not be described in detail here.

[0292] This embodiment also provides a computer-readable storage medium storing a computer program. When executed by a processor (e.g., the controller 200 described above), the computer-readable storage medium causes the processor to implement the steps of the sample analysis method described above. The computer-readable storage medium may be an internal storage unit of the sample analysis device 10 described above, such as a hard drive or memory of the sample analysis device 10; or, the computer-readable storage medium may be an external storage device of the sample analysis device 10, such as a plug-in hard drive, a smart media card (SMC), a secure digital (SD) card, a flash memory card, etc., provided on the sample analysis device 10.

[0293] As an implementation manner, in the sample analysis device 10 and the sample analysis method provided in this embodiment, the sample distribution device 150, the reaction container supply device 130, the sample injection device 190, the first transfer mechanism 141, and the fourth transfer mechanism 144 are common devices of each measuring device (in this embodiment, the first measuring device 110 and the second measuring device 120), that is, each measuring device shares the sample distribution device 150, the reaction container supply device 130, the sample injection device 190, the first transfer mechanism 141, and the fourth transfer mechanism 144. These common devices are mainly used to complete the sample loading processing for each measuring device.

[0294] As an implementation manner, in the sample analysis device 10 and the sample analysis method provided in this embodiment, the first measuring device 110 and the second measuring device 120 use the same reaction container. The following steps are the same for the first measuring device 110 and the second measuring device 120: moving the reaction container from the hopper to the sample loading position, dispensing the sample into the reaction container, etc. That is, these steps of the first measuring device 110 and the second measuring device 120 are exactly the same and are shared by the first measuring device 110 and the second measuring device 120.

[0295] As an embodiment, the sample analysis device 10 is an integrated machine for coagulation detection and immunoassay. The two measuring devices in the integrated machine (i.e., the first measuring device 110 and the second measuring device 120) share a sample needle for sample distribution, a common automatic sample injector (i.e., the sample injector 190) for automatic injection, a common hopper (i.e., the hopper of the reaction vessel supply device 130) for loading the reaction vessel, a common gripper for transferring the reaction vessel after sample loading to the first transfer area 101, and a common conveying track for transfer of the reaction vessel within the first transfer area 101, which is more conducive to the miniaturization of the integrated machine; in addition, each measuring device is independent of each other and does not affect each other.

[0296] As an embodiment, the workflow of the sample analysis device 10 includes:

[0297] The sample rack 50 containing the sample to be tested is placed on the sampling device 190 (i.e., the automatic sampler), and the reaction container is placed in the hopper of the reaction container supply device 130. When a test instruction is received, the reaction container supply device 130 provides the reaction container to the sample loading position, and then the shared sample needle draws the sample from the sample rack 50 to be tested at the sample suction position on the sampling device 190, and completes the sample loading at the sample loading position. Then, the clamp of the first transfer mechanism 141 transfers the reaction container with the sample to the first transfer position 1011 of the shared track.

[0298] If the received test instruction is for a test using the first measuring device 110 (coagulation testing system), the transport track of the fourth transfer mechanism 144 transports the reaction container containing the sample (i.e., the first reaction container 20) to the second intermediate transfer position 1012. The gripper of the second transfer mechanism 142 then grabs the first reaction container 20 containing the sample from the second intermediate transfer position 1012 and places it in the first measuring device 110 for a normal coagulation test. After the test is completed, the first reaction container 20 is discarded for recycling.

[0299] If the received test instruction is for a measurement using the second measuring device 120 (immunoassay system), the transport track of the fourth transfer mechanism 144 transports the reaction container containing the sample (i.e., the second reaction container 30) to the third transfer station 1013. The gripper of the third transfer mechanism 143 then grasps the second reaction container 30 containing the sample from the third transfer station 1013 and transfers it to the second measuring device 120 for a normal immunoassay measurement. After the measurement is completed, the second reaction container 30 is discarded and recycled.

[0300] Example 2:

[0301] 1 , 2 , 3 , and 6 , the sample analysis device 10 and sample analysis method provided in this embodiment differ from those in the first embodiment primarily in the different configuration of the first transfer area 101 . Specifically, in the first embodiment, the first transfer area 101 includes three transfer positions; whereas in this embodiment, the first transfer area 101 includes only one transfer position.

[0302] As an embodiment, in this embodiment, the first transfer area 101 includes a fourth transfer position 1014; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with samples and the loaded samples used for coagulation detection items from the reaction container supply device 130 to the fourth transfer position 1014, and control the transfer device 140 to transfer the first reaction container 20 from the fourth transfer position 1014 to the first incubation mechanism 111; the controller 200 is also configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with samples and the loaded samples used for non-coagulation detection items from the reaction container supply device 130 to the fourth transfer position 1014, and control the transfer device 140 to transfer the second reaction container 30 from the fourth transfer position 1014 to the second incubation mechanism 121. In this embodiment, after the sample addition is completed, the first reaction container 20 and the second reaction container 30 are both transferred from the sample addition position to the fourth intermediate transfer position 1014 by the transfer device 140. The first reaction container 20 is then transferred from the fourth intermediate transfer position 1014 to the first measuring device 110 by the transfer device 140, and the second reaction container 30 is transferred from the fourth intermediate transfer position 1014 to the second measuring device 120 by the transfer device 140. The fourth intermediate transfer position 1014 in this embodiment can also be equivalent to integrating the first intermediate transfer position 1011, the second intermediate transfer position 1012, and the third intermediate transfer position 1013 in the first embodiment into one, or can be equivalent to omitting the second intermediate transfer position 1012 and the third intermediate transfer position 1013 in the first embodiment.

[0303] As one embodiment, the transfer device 140 includes a first transfer mechanism 141, a second transfer mechanism 142, a third transfer mechanism 143, and a ninth transfer mechanism 145. The first transfer mechanism 141 is used to transfer the first reaction container 20 loaded with a sample from the sample loading position to the fourth intermediate transfer position 1014 under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with a sample from the sample loading position to the fourth intermediate transfer position 1014 under the control of the controller 200. The second transfer mechanism 142 is used to transfer the first reaction container 20 located at the fourth intermediate transfer position 1014 and used for coagulation test items to the first incubation mechanism 111 under the control of the controller 200; and the third transfer mechanism 143 is used to transfer the second reaction container 30 located at the fourth intermediate transfer position 1014 and used for non-coagulation test items to the second incubation mechanism 121 under the control of the controller 200. The ninth transfer mechanism 145 is used in a time-sharing manner to implement the following operations: transferring the first reaction container 20 loaded with the incubated product from the buffer station to the trigger reagent adding station; driving the first reaction container 20 after the trigger reagent is added to swing and / or vibrate to mix the liquid in the first reaction container 20 to prepare a first sample; transferring the first reaction container 20 loaded with the first sample from the trigger reagent adding station to the first measuring component 112; transferring the first reaction container 20 after the measurement is completed from the first measuring component 112 to the first cup throwing position for the cup throwing operation.

[0304] Except for the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can refer to the first embodiment and will not be described in detail here.

[0305] Example 3:

[0306] 1 , 2 , 3 , and 7 , the sample analysis device 10 and sample analysis method provided in this embodiment differ from those in the first embodiment primarily in the different configuration of the first transfer area 101 . Specifically, in the first embodiment, the first transfer area 101 includes three transfer positions; whereas in this embodiment, the first transfer area 101 includes only two transfer positions.

[0307] As an embodiment, in this embodiment, the first transfer area 101 includes a fifth transfer position and a sixth transfer position; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with samples and the loaded samples used for coagulation detection items from the reaction container supply device 130 to the fifth transfer position, control the transfer device 140 to transfer the first reaction container 20 from the fifth transfer position to the sixth transfer position, and control the transfer device 140 to transfer the first reaction container 20 from the sixth transfer position to the first incubation mechanism 111; the controller 200 is also configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with samples and the loaded samples used for non-coagulation detection items from the reaction container supply device 130 to the fifth transfer position, control the transfer device 140 to transfer the second reaction container 30 from the fifth transfer position to the sixth transfer position, and control the transfer device 140 to transfer the second reaction container 30 from the sixth transfer position to the second incubation mechanism 121. In this embodiment, after the sample addition is completed, the first reaction container 20 and the second reaction container 30 are both transferred from the sample loading position to the fifth intermediate transfer position by the transfer device 140. The first reaction container 20 and the second reaction container 30 are then transferred from the fifth intermediate transfer position to the sixth intermediate transfer position by the transfer device 140. The first reaction container 20 and the second reaction container 30 are then transferred from the sixth intermediate transfer position to the first measuring device 110 by the transfer device 140, and the second reaction container 30 is transferred from the sixth intermediate transfer position to the second measuring device 120 by the transfer device 140. The fifth intermediate transfer position in this embodiment is equivalent to the first intermediate transfer position 1011 in the first embodiment, and the sixth intermediate transfer position is equivalent to integrating the second intermediate transfer position 1012 and the third intermediate transfer position 1013 in the first embodiment, or can be equivalent to omitting one of the second intermediate transfer position 1012 and the third intermediate transfer position 1013 in the first embodiment.

[0308] As one embodiment, the transfer device 140 includes a first transfer mechanism 141, a second transfer mechanism 142, a third transfer mechanism 143, a fourth transfer mechanism 144, and a ninth transfer mechanism 145. The first transfer mechanism 141 is used to transfer the first reaction container 20 loaded with the sample from the sample loading position to the fifth intermediate transfer position under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with the sample from the sample loading position to the fifth intermediate transfer position under the control of the controller 200. The fourth transfer mechanism 144 is used to transfer the first reaction container 20 loaded with the sample from the fifth intermediate transfer position to the sixth intermediate transfer position under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with the sample from the fifth intermediate transfer position to the sixth intermediate transfer position under the control of the controller 200. The second transfer mechanism 142 is used to transfer the first reaction container 20 located at the sixth transfer position and used for coagulation test items to the first incubation mechanism 111 under the control of the controller 200. The third transfer mechanism 143 is used to transfer the second reaction container 30 located at the sixth transfer position and used for non-coagulation test items to the second incubation mechanism 121 under the control of the controller 200. The ninth transfer mechanism 145 is used in a time-sharing manner to implement the following operations: transferring the first reaction container 20 loaded with the incubated liquid from the buffer station to the trigger reagent addition station; driving the first reaction container 20 after the trigger reagent is added to swing and / or vibrate to mix the liquid in the first reaction container 20 to prepare a first sample; transferring the first reaction container 20 loaded with the first sample from the trigger reagent addition station to the first measurement unit 112; and transferring the first reaction container 20 after the measurement is completed from the first measurement unit 112 to the first cup throwing position for cup throwing.

[0309] Except for the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can refer to the first embodiment and will not be described in detail here.

[0310] Example 4:

[0311] 1 , 2 , 3 and 8 , the sample analysis device 10 and sample analysis method provided in this embodiment differ from those in the first embodiment primarily in that the first transfer area 101 is configured differently, specifically, in the first embodiment, the first transfer area 101 includes three transfer positions; whereas in this embodiment, the first transfer area 101 includes only two transfer positions, and these two transfer positions are different from the two transfer positions in the third embodiment.

[0312] As an embodiment, in this example, the first transfer area 101 includes a second transfer position 1012 and a third transfer position 1013; the controller 200 is configured to: control the transfer device 140 to transfer a first reaction container 20 loaded with a sample for use in coagulation testing from the reaction container supply device 130 to the second transfer position 1012, and control the transfer device 140 to transfer the first reaction container 20 from the second transfer position 1012 to the first incubation mechanism 111. The controller 200 is further configured to: control the transfer device 140 to transfer a second reaction container 30 loaded with a sample for use in non-coagulation testing from the reaction container supply device 130 to the third transfer position 1013, and control the transfer device 140 to transfer the second reaction container 30 from the third transfer position 1013 to the second incubation mechanism 121. In this embodiment, after sample loading, the first reaction container 20 is transferred from the sample loading position to the second intermediate transfer position 1012 by the transfer device 140, and then the first reaction container 20 is transferred from the second intermediate transfer position 1012 to the first measuring device 110 by the transfer device 140. After sample loading, the second reaction container 30 is transferred from the sample loading position to the third intermediate transfer position 1013 by the transfer device 140, and then the second reaction container 30 is transferred from the third intermediate transfer position 1013 to the second measuring device 120 by the transfer device 140. In this embodiment, the first intermediate transfer position 1011 in the first embodiment is omitted.

[0313] As one embodiment, the transfer device 140 includes a first transfer mechanism 141, a second transfer mechanism 142, a third transfer mechanism 143, and a ninth transfer mechanism 145. The first transfer mechanism 141 is used to transfer the first reaction container 20 loaded with a sample from the sample loading position to the second intermediate transfer position 1012 under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with a sample from the sample loading position to the third intermediate transfer position 1013 under the control of the controller 200. The second transfer mechanism 142 is used to transfer the first reaction container 20 located at the second intermediate transfer position 1012 and used for coagulation test items to the first incubation mechanism 111 under the control of the controller 200; and the third transfer mechanism 143 is used to transfer the second reaction container 30 located at the third intermediate transfer position 1013 and used for non-coagulation test items to the second incubation mechanism 121 under the control of the controller 200. The ninth transfer mechanism 145 is used in a time-sharing manner to implement the following operations: transferring the first reaction container 20 loaded with the incubated product from the buffer station to the trigger reagent adding station; driving the first reaction container 20 after the trigger reagent is added to swing and / or vibrate to mix the liquid in the first reaction container 20 to prepare a first sample; transferring the first reaction container 20 loaded with the first sample from the trigger reagent adding station to the first measuring component 112; transferring the first reaction container 20 after the measurement is completed from the first measuring component 112 to the first cup throwing position for the cup throwing operation.

[0314] Except for the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can refer to the first embodiment and will not be described in detail here.

[0315] Embodiment 5:

[0316] 1 , 2 , 3 and 9 , the sample analysis device 10 and the sample analysis method provided in this embodiment differ from those in the first embodiment mainly in that the reagent dispensing device 160, the reagent tray and the incubation mechanism are arranged differently, as follows: in the first embodiment, the reagents used by the first measuring device 110 and the second measuring device 120 are stored separately on different reagent trays, the reagent dispensing operations of the first measuring device 110 and the second measuring device 120 are performed separately by different reagent dispensing mechanisms, and the incubation operations of the first measuring device 110 and the second measuring device 120 are performed separately in different incubation mechanisms; whereas in this embodiment, the reagents used by the first measuring device 110 and the second measuring device 120 are stored on the same reagent tray, the reagent dispensing operations of the first measuring device 110 and the second measuring device 120 are performed by the same reagent dispensing mechanism, and the incubation operations of the first measuring device 110 and the second measuring device 120 are performed in the same incubation mechanism.

[0317] As an embodiment, in this embodiment, the reagent dispensing device 160 includes a third reagent dispensing mechanism 163; the sample analysis device 10 also includes a third reagent tray, the third reagent tray is used to carry a first reagent container and a second reagent container, the first reagent container is used to load a first type of reagent for measuring a coagulation test item, and the second reagent container is used to load a second type of reagent for measuring a non-coagulation test item; the third reagent dispensing mechanism 163 is used to draw the first type of reagent from the first reagent container and dispense the drawn first type of reagent into the first reaction container 20 loaded with the sample, and is used to draw the second type of reagent from the second reagent container and dispense the drawn second type of reagent into the second reaction container 30 loaded with the sample; the first measuring device 110 and The second measuring device 120 includes a third incubation mechanism for incubating the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid, and for incubating the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid. The first measuring device 110 also includes a first measuring component 112 for performing a coagulation test on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container 20. The second measuring device 120 also includes a second measuring component 122 for performing a non-coagulation test on the second sample prepared from at least the fourth liquid in the second reaction container 30. In this embodiment, the coagulation test performed by the first measuring device 110 and the non-coagulation test performed by the second measuring device 120 share the same reagent disk, the same reagent dispensing mechanism, and the same incubation mechanism. This simplifies the structure of the sample analyzing device 10 and reduces the cost and volume of the sample analyzing device 10.

[0318] As an embodiment, the transfer device 140 includes a fifth transfer mechanism 146, a sixth transfer mechanism 147 and a seventh transfer mechanism 148. The fifth transfer mechanism 146 is used to transfer the first reaction container 20 loaded with the sample from the reaction container supply device 130 to the second transfer area under the control of the controller 200, and is used to transfer the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the second transfer area under the control of the controller 200; the sixth transfer mechanism 147 is used to transfer the first reaction container 20 located at the second transfer area to the third incubation mechanism under the control of the controller 200, and is used to transfer the second reaction container 30 located at the second transfer area to the third incubation mechanism under the control of the controller 200; the seventh transfer mechanism 148 is used to transfer the first reaction container 20 located at the third incubation mechanism and used for coagulation detection item determination to the first measurement component 112 under the control of the controller 200, and is used to transfer the second reaction container 30 located at the third incubation mechanism and used for non-coagulation detection item determination to the second measurement component 122 under the control of the controller 200. The coagulation test items performed by the first measuring device 110 and the non-coagulation test items performed by the second measuring device 120 share a transfer area. In this embodiment, after the sample is added, the first reaction container 20 and the second reaction container 30 are first transferred from the sample loading position to the same transfer area (i.e., the second transfer area) for transfer, and then transferred from the transfer area to the third incubation mechanism. This helps to simplify the motion trajectory of a single transfer action of the transfer device 140. Of course, in a specific application, as an alternative embodiment, at least one of the first reaction container 20 and the second reaction container 30 can also be directly transferred from the sample loading position to the third incubation mechanism after the sample is added, without having to be transferred to the transfer area for transfer first.

[0319] As an embodiment, the seventh transfer mechanism 148 is also used to transfer the incubated second reaction container 30 from the second incubation mechanism 121 to the magnetic separation mechanism 123; and transfer the magnetically separated second reaction container 30 to the second measurement carrier 1222 for measurement.

[0320] In one embodiment, the second transfer area includes a seventh transfer position and an eighth transfer position; the fifth transfer mechanism 146 is used to transfer the first reaction container 20 loaded with the sample from the reaction container supply device 130 to the seventh transfer position under the control of the controller 200, and to transfer the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the seventh transfer position under the control of the controller 200. The transfer device 140 also includes an eighth transfer mechanism 149, which is used to transfer the first reaction container 20 located at the seventh transfer position to the eighth transfer position under the control of the controller 200, and to transfer the second reaction container 30 located at the seventh transfer position to the eighth transfer position under the control of the controller 200. The sixth transfer mechanism 147 is used to transfer the first reaction container 20 located at the eighth transfer position to the third incubation mechanism under the control of the controller 200, and to transfer the second reaction container 30 located at the eighth transfer position to the third incubation mechanism under the control of the controller 200. The seventh intermediate transfer position in this embodiment is equivalent to the first intermediate transfer position 1011 in the first embodiment, and the eighth intermediate transfer position is equivalent to the integration of the second intermediate transfer position 1012 and the third intermediate transfer position 1013 in the first embodiment. The fifth transfer mechanism 146 is equivalent to the first transfer mechanism 141 in the first embodiment, and the eighth transfer mechanism 149 is equivalent to the fourth transfer mechanism 144 in the first embodiment.

[0321] Of course, in specific applications, the transfer method of the reaction containers in the second transfer area is not limited to the above method. For example, as an alternative embodiment, the second transfer area includes a ninth transfer position and a tenth transfer position; the fifth transfer mechanism 146 is used to transfer the first reaction container 20 loaded with the sample from the reaction container supply device 130 to the ninth transfer position under the control of the controller 200, and the sixth transfer mechanism 147 is used to transfer the first reaction container 20 located at the ninth transfer position to the third incubation mechanism under the control of the controller 200; the fifth transfer mechanism 146 is also used to transfer the second reaction container 30 loaded with the sample from the reaction container supply device 130 to the tenth transfer position under the control of the controller 200, and the sixth transfer mechanism 147 is also used to transfer the second reaction container 30 located at the tenth transfer position to the third incubation mechanism under the control of the controller 200. In this alternative embodiment, after the first reaction container 20 and the second reaction container 30 are loaded with the sample, they are respectively transferred to different transfer positions and then transferred from different transfer positions to the same incubation mechanism.

[0322] As an embodiment, the third reagent dispensing mechanism 163 includes a first sub-reagent dispensing mechanism 1631 and a second sub-reagent dispensing mechanism 1632. The first sub-reagent dispensing mechanism 1631 is used to draw a mixed reagent from a mixed reagent container and dispense it into the first reaction container 20, and to draw a second type of reagent from a second type of reagent container and dispense it into the second reaction container 30. The second sub-reagent dispensing mechanism 1632 is used to draw a trigger reagent from a trigger reagent container and dispense it into the first reaction container 20.

[0323] In one embodiment, the first sub-reagent dispensing mechanism 1631 includes a second reagent needle, a fifth aspiration / discharge drive component for driving the second reagent needle to aspirate and discharge mixed reagents, and a fifth motion drive component for driving the second reagent needle to perform spatial motion. The second sub-reagent dispensing mechanism 1632 includes a third reagent needle, a sixth aspiration / discharge drive component for driving the third reagent needle to aspirate and discharge mixed reagents, and a sixth motion drive component for driving the third reagent needle to perform spatial motion.

[0324] As an implementation method, the workflow of the sample analysis device 10 provided in this embodiment includes:

[0325] After receiving the measurement command, the reaction container supply device 130 provides the reaction container to the sample loading position, the sample injection device 190 (i.e., the automatic sampler) transfers the sample container 40 to the sample aspiration position, the sample needle aspirates the sample from the sample container 40 at the sample aspiration position, and adds the sample at the sample loading position. The clamp of the fifth transfer mechanism 146 then transfers the reaction container with the sample to the seventh transfer position, and the eighth transfer mechanism 149 then transfers the reaction container to the eighth transfer position, and then the sixth transfer mechanism 147 transfers the reaction container to the third incubation mechanism for incubation.

[0326] If the received command is for a coagulation test, the first type of reagent is directly added via the reagent needle, and then the clamp of the seventh transfer mechanism 148 transfers the reaction container to the first test carrier 1123 for coagulation test measurement.

[0327] If the command received is for an immunoassay project, the reagent needle adds the second type of reagent, and then the clamp of the seventh transfer mechanism 148 transfers the reagent to the magnetic separation mechanism 123 for magnetic separation operation, and then the clamp of the seventh transfer mechanism 148 transfers the reaction container to the second measurement carrier 1222 for the immunoassay project.

[0328] Except for the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can refer to the first to fourth embodiments and will not be described in detail here.

[0329] Example 6:

[0330] 1 , 2 , 9 , and 10 , the sample analysis device 10 and sample analysis method provided in this embodiment differ from those in the fifth embodiment primarily in that the reagent dispensing device 160 is configured differently. Specifically, in the fifth embodiment, the reagent dispensing operations of the first measuring device 110 and the second measuring device 120 are performed by the same reagent dispensing mechanism; whereas in this embodiment, the reagent dispensing operations of the first measuring device 110 and the second measuring device 120 are performed separately by different reagent dispensing mechanisms.

[0331] As an embodiment, in this embodiment, the reagent dispensing device 160 includes a fourth reagent dispensing mechanism 164 and a fifth reagent dispensing mechanism 165; the sample analysis device 10 also includes a third reagent tray, the third reagent tray is used to carry a first reagent container and a second reagent container, the first reagent container is used to load a first type of reagent for measuring a coagulation test item, and the second reagent container is used to load a second type of reagent for measuring a non-coagulation test item; the fourth reagent dispensing mechanism 164 is used to absorb the first type of reagent from the first reagent container of the third reagent tray and dispense at least part of the absorbed first type of reagent into the first reaction container 20 loaded with the sample; the fifth reagent dispensing mechanism 165 is used to absorb the second type of reagent from the second reagent container of the third reagent tray and dispense at least part of the absorbed second type of reagent into the first reaction container 20 loaded with the sample The first measuring device 110 and the second measuring device 120 jointly include a third incubation mechanism, which is used to incubate the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid, and to incubate the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid; the first measuring device 110 also includes a first measuring component 112, which is used to perform a coagulation test on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container 20; the second measuring device 120 also includes a second measuring component 122, which is used to perform a non-coagulation test on the second sample prepared from at least the fourth liquid in the second reaction container 30. In this embodiment, the coagulation test items performed by the first measuring device 110 and the non-coagulation test items performed by the second measuring device 120 share the same reagent disk and the same incubation mechanism, but do not share the reagent dispensing mechanism.

[0332] As an embodiment, the fourth reagent dispensing mechanism 164 includes a mixed reagent dispensing mechanism 1611 and a trigger reagent dispensing mechanism 1612. The mixed reagent dispensing mechanism 1611 is used to draw the mixed reagent from the mixed reagent container of the third reagent disk and distribute it to the first reaction container 20. The trigger reagent dispensing mechanism 1612 is used to draw the trigger reagent from the trigger reagent container of the third reagent disk and distribute it to the first reaction container 20. The mixed reagent dispensing mechanism 1611 and the trigger reagent dispensing mechanism 1612 are set independently of each other. The mixed reagent dispensing mechanism 1611 and the trigger reagent dispensing mechanism 1612 can work in parallel, so that the mixed reagent dispensing operation of one first reaction container 20 can be performed simultaneously with the trigger reagent dispensing operation of another first reaction container 20. Of course, in specific applications, as an alternative embodiment, the mixed reagent dispensing operation and the trigger reagent dispensing operation can also be performed by the same reagent dispensing mechanism.

[0333] Except for the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can refer to the first to fifth embodiments and will not be described in detail here.

[0334] Embodiment seven:

[0335] 1 , 2 , 10 , and 11 , the sample analysis device 10 and sample analysis method provided in this embodiment differ from those of the sixth embodiment primarily in the manner in which the reagent discs are arranged. Specifically, in the sixth embodiment, the reagents used by the first measuring device 110 and the second measuring device 120 are stored on the same reagent disc; whereas in this embodiment, the reagents used by the first measuring device 110 and the second measuring device 120 are stored separately on different reagent discs.

[0336] As an implementation manner, in this embodiment, the reagent dispensing device 160 includes a sixth reagent dispensing mechanism 166 and a seventh reagent dispensing mechanism 167; the sample analysis device 10 also includes a first reagent tray 170 and a second reagent tray 180, the first reagent tray 170 is used to carry a first reagent container, the first reagent container is loaded with a first type of reagent for performing coagulation detection items; the second reagent tray 180 is used to carry a second reagent container, the second reagent container is loaded with a second type of reagent for performing non-coagulation detection items; the sixth reagent dispensing mechanism 166 is used to absorb the first type of reagent from the first reagent container of the first reagent tray 170 and dispense at least part of the absorbed first type of reagent into the first reaction container 20 loaded with the sample; the seventh reagent dispensing mechanism 167 is used to absorb the second type of reagent from the second reagent container of the second reagent tray 180 and dispense the absorbed second type of reagent into the first reaction container 20 loaded with the sample. At least a portion of the second type of reagent is dispensed into the second reaction container 30 containing the sample. The first measuring device 110 and the second measuring device 120 jointly include a third incubation mechanism, which is used to incubate the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid, and to incubate the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid. The first measuring device 110 also includes a first measuring component 112, which is used to perform a coagulation test on a first sample prepared from at least the second liquid and the first type of reagent in the first reaction container 20. The second measuring device 120 also includes a second measuring component 122, which is used to perform a non-coagulation test on a second sample prepared from at least the fourth liquid in the second reaction container 30. In this embodiment, the coagulation test performed by the first measuring device 110 and the non-coagulation test performed by the second measuring device 120 share the same incubation mechanism, but do not share the reagent disk and reagent dispensing mechanism.

[0337] As an embodiment, the sixth reagent dispensing mechanism 166 includes a mixed reagent dispensing mechanism 1611 and a trigger reagent dispensing mechanism 1612. The mixed reagent dispensing mechanism 1611 is used to draw a mixed reagent from the mixed reagent container of the first reagent disk 170 and dispense it into the first reaction container 20. The trigger reagent dispensing mechanism 1612 is used to draw a trigger reagent from the trigger reagent container of the first reagent disk 170 and dispense it into the first reaction container 20. The mixed reagent dispensing mechanism 1611 and the trigger reagent dispensing mechanism 1612 are independently provided and can operate in parallel.

[0338] Apart from the above differences, other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can be referred to in Embodiments 1 to 6 and will not be described in detail here.

[0339] Embodiment 8:

[0340] The sample analysis device 10 and sample analysis method provided in this embodiment differ from those in the first embodiment primarily in their respective protection emphases. Specifically, in the first embodiment, the focus was on protecting an all-in-one device having at least two different measuring devices that share a common reaction vessel supply device 130. In contrast, in this embodiment, the focus is on protecting an all-in-one device having at least two different measuring devices that do not perform secondary sample packaging.

[0341] Specifically, the sample analysis device 10 provided in this embodiment includes a first identification component 300, a second identification component 500, a sample dispensing device 150, a reagent dispensing device 160, a controller 200, and at least two measuring devices. The first identification component 300 is used to identify the sample container 40 containing the sample. The second identification component 500 is used to identify the reagent container, which includes a first reagent container and a second reagent container. The first reagent container is loaded with a first type of reagent, and the second reagent container is loaded with a second type of reagent. The sample dispensing device 150 is used to draw the sample from the sample container 40 after being identified by the first identification component, and to distribute at least part of the drawn sample to a reaction container. The reagent dispensing device 160 is used to draw the first type of reagent from the first reagent container after being identified by the second identification component 500, and to distribute at least part of the drawn first type of reagent to the reaction container; and is used to draw the second type of reagent from the second reagent container after being identified by the second identification component 500, and to distribute at least part of the drawn second type of reagent to the reaction container. The at least two measuring devices include a first measuring device 110 and a second measuring device 120. The first measuring device 110 is used to measure coagulation test items on the sample, and the second measuring device 120 is used to measure non-coagulation test items on the sample. The controller 200 is configured to: obtain at least the test item to be measured of the sample in the sample container 40 based on the feedback information of the first identification component 300; and obtain at least information about the reagent in the reagent container based on the feedback information of the second identification component 500. The controller 200 is further configured to: control the sample dispensing device 150 to aspirate the sample from the sample container 40 identified by the first identification component 300 and dispense at least a portion of the aspirated sample into the first reaction container 20; control the reagent dispensing device 160 to aspirate the first type of reagent from the first reagent container identified by the second identification component 500 and dispense it into the first reaction container 20; and control the first measuring device 110 to perform a coagulation test on a first specimen prepared from at least the sample and the first type of reagent in the first reaction container 20. The controller 200 is further configured to: control the sample dispensing device 150 to draw a sample from the sample container 40 identified by the first identification component 300 and dispense at least a portion of the drawn sample into the second reaction container 30; control the reagent dispensing device 160 to draw a second type of reagent from the second reagent container identified by the second identification component 500 and dispense it into the second reaction container 30; and control the second measuring device 120 to perform a non-coagulation test on a second specimen prepared from at least the sample and the second type of reagent in the second reaction container 30. In this embodiment, by configuring the first measuring device 110 to perform a coagulation test on the sample and configuring the second measuring device 120 to perform a non-coagulation test on the sample, the coagulation and non-coagulation test functions are integrated into a single sample analyzer 10.Furthermore, when performing coagulation and non-coagulation tests on samples, this embodiment directly dispenses the sample from the sample container 40 into the reaction container corresponding to the test item, and directly dispenses the reagent from the reagent container into the reaction container corresponding to the test item, eliminating the need for secondary packaging of the sample and reagent. This effectively ensures the testing efficiency of each test item and reduces unnecessary consumption of reaction containers.

[0342] As an embodiment, the first reaction container 20 and the second reaction container 30 are reaction containers of the same shape and / or size. The arrangement scheme here can refer to the description in Example 1 and will not be described in detail here.

[0343] As an embodiment, the first reaction container 20 and the second reaction container 30 are the same reaction container. The arrangement scheme here can refer to the description in Example 1 and will not be described in detail here.

[0344] As an embodiment, the non-coagulation test items measured by the second measuring device 120 are immunoassay items or biochemical test items. The setting scheme here can refer to the description in the first embodiment and will not be described in detail here.

[0345] As an embodiment, the sample analysis device 10 further includes a transfer device 140 , which is used to transfer the reaction container.

[0346] As an embodiment, the controller 200 is further configured to: when the test item of the sample to be tested includes a coagulation test item, use at least one reaction container as the first reaction container 20, control the sample dispensing device 150 to absorb the sample from the sample container 40, and distribute at least part of the absorbed sample to the first reaction container 20; control the transfer device 140 to transfer the first reaction container 20 loaded with the sample to the first measuring device 110, control the reagent dispensing device 160 to absorb the first type of reagent from the first reagent container, and distribute at least part of the absorbed first type of reagent to the first reaction container 20 loaded with the sample in the first measuring device 110; control the first measuring device 110 to measure the first sample prepared by at least the sample and the first type of reagent in the first reaction container 20; when the test item of the sample to be tested includes a coagulation test item, use at least one reaction container as the first reaction container 20, control the sample dispensing device 150 to absorb the sample from the sample ... and distribute at least part of the absorbed first type of reagent to the first reaction container 20 loaded The system includes a non-coagulation test project, uses at least one reaction container as a second reaction container 30, controls the sample dispensing device 150 to draw a sample from the sample container 40 and distribute at least a portion of the drawn sample to the second reaction container 30, controls the transfer device 140 to transfer the second reaction container 30 loaded with the sample to the second measuring device 120, controls the reagent dispensing device 160 to draw a second type of reagent from the second reagent container and distribute at least a portion of the drawn second type of reagent to the second reaction container 30 loaded with the sample in the second measuring device 120, controls the second measuring device 120 to measure a second sample prepared from at least the sample and the second type of reagent in the second reaction container 30, and analyzes and obtains the sample measurement result based on the feedback information from the first measuring device 110 and / or the second measuring device 120. The configuration scheme herein can be referred to the description in Example 1 and will not be described in detail here.

[0347] As an embodiment, the reagent dispensing device 160 includes a first reagent dispensing mechanism 161 and a second reagent dispensing mechanism 162; the sample analysis device 10 also includes a first reagent tray 170 and a second reagent tray 180, the first reagent tray 170 is used to carry a first reagent container, the first reagent container is loaded with a first type of reagent for performing a coagulation test item, the first reagent dispensing mechanism 161 is used to absorb the first type of reagent from the first reagent container and dispense at least part of the absorbed first type of reagent into the first reaction container 20 loaded with the sample; the second reagent tray 180 is used to carry a second reagent container, the second reagent container is loaded with a second type of reagent for performing a non-coagulation test item, the second reagent dispensing mechanism 162 is used to absorb the second type of reagent from the second reagent container and dispense the absorbed second type of reagent into the first reaction container 20 loaded with the sample. The second reaction container 30 containing the sample; the first measuring device 110 includes a first incubation mechanism 111 and a first measuring component 112, the first incubation mechanism 111 is used to incubate the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid, and the first measuring component 112 is used to measure the coagulation test items of the first sample prepared by at least the second liquid and the first type of reagent in the first reaction container 20; the second measuring device 120 includes a second incubation mechanism 121 and a second measuring component 122, the second incubation mechanism 121 is used to incubate the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid, and the second measuring component 122 is used to measure the non-coagulation test items of the second sample prepared by at least the fourth liquid in the second reaction container 30. The setting scheme here can be referred to the description in Example 1 and will not be described in detail here.

[0348] As an embodiment, the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample and used for the measurement of a coagulation test item from the reaction container supply device 130 to the first transfer area 101, and control the transfer device 140 to transfer the first reaction container 20 from the first transfer area 101 to the first incubation mechanism 111; the controller 200 is further configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample and used for the measurement of a non-coagulation test item from the reaction container supply device 130 to the first transfer area 101, and control the transfer device 140 to transfer the second reaction container 30 from the first transfer area 101 to the second incubation mechanism 121. The setting scheme here can be referred to the description in Example 1 and will not be described in detail here.

[0349] As an embodiment, the first transfer area 101 includes a first transfer position 1011, a second transfer position 1012 and a third transfer position 1013; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample for performing a coagulation test from the sample loading position to the first transfer position 1011, control the transfer device 140 to transfer the first reaction container 20 from the first transfer position 1011 to the second transfer position 1012, and control the transfer device 140 to transfer the first reaction container 20 from the first transfer position 1011 to the second transfer position 1012. 0 from the second intermediate transfer position 1012 to the first incubation mechanism 111; the controller 200 is further configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample for non-coagulation test items from the sample loading position to the first intermediate transfer position 1011, control the transfer device 140 to transfer the second reaction container 30 from the first intermediate transfer position 1011 to the third intermediate transfer position 1013, and control the transfer device 140 to transfer the second reaction container 30 from the third intermediate transfer position 1013 to the second incubation mechanism 121. The setting scheme here can be referred to the description in Example 1 and will not be described in detail here.

[0350] As a first alternative embodiment of the above-mentioned arrangement of the first transfer area 101, the first transfer area 101 includes a fourth transfer position 1014; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample for coagulation test items from the sample loading position to the fourth transfer position 1014, and control the transfer device 140 to transfer the first reaction container 20 from the fourth transfer position 1014 to the first incubation mechanism 111; the controller 200 is further configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample for non-coagulation test items from the sample loading position to the fourth transfer position 1014, and control the transfer device 140 to transfer the second reaction container 30 from the fourth transfer position 1014 to the second incubation mechanism 121. The arrangement scheme here can be referred to the description in Example 2 and will not be described in detail here.

[0351] As a second alternative embodiment of the above-mentioned setting scheme of the first transfer area 101, the first transfer area 101 includes a fifth transfer position and a sixth transfer position; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample and the loaded sample used for coagulation detection item determination from the sample loading position to the fifth transfer position, control the transfer device 140 to transfer the first reaction container 20 from the fifth transfer position to the sixth transfer position, and control the transfer device 140 to transfer the first reaction container 20 from the sixth transfer position to the first incubation mechanism 111; the controller 200 is also configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample and the loaded sample used for non-coagulation detection item determination from the sample loading position to the fifth transfer position, control the transfer device 140 to transfer the second reaction container 30 from the fifth transfer position to the sixth transfer position, and control the transfer device 140 to transfer the second reaction container 30 from the sixth transfer position to the second incubation mechanism 121. The configuration scheme here can refer to the description in Example 3 and will not be described in detail here.

[0352] As a third alternative embodiment of the above-mentioned arrangement of the first transfer area 101, the first transfer area 101 includes a second transfer position 1012 and a third transfer position 1013; the controller 200 is configured to: control the transfer device 140 to transfer the first reaction container 20 loaded with a sample for coagulation test items from the sample loading position to the second transfer position 1012, and control the transfer device 140 to transfer the first reaction container 20 from the second transfer position 1012 to the first incubation mechanism 111; the controller 200 is further configured to: control the transfer device 140 to transfer the second reaction container 30 loaded with a sample for non-coagulation test items from the sample loading position to the third transfer position 1013, and control the transfer device 140 to transfer the second reaction container 30 from the third transfer position 1013 to the second incubation mechanism 121. The arrangement scheme here can be referred to the description in Example 4 and will not be described in detail here.

[0353] As a first alternative embodiment of the above-mentioned reagent dispensing device 160, reagent tray, and incubation mechanism setting scheme, the reagent dispensing device 160 includes a third reagent dispensing mechanism 163; the sample analysis device 10 also includes a third reagent tray, the third reagent tray is used to carry a first reagent container and a second reagent container, the first reagent container is used to load a first type of reagent for coagulation detection items, and the second reagent container is used to load a second type of reagent for non-coagulation detection items; the third reagent dispensing mechanism 163 is used to draw the first type of reagent from the first reagent container and dispense at least part of the drawn first type of reagent into the first reaction container 20 loaded with the sample, and is used to draw the second type of reagent from the second reagent container and dispense at least part of the drawn second type of reagent into the second reaction container 20 loaded with the sample. The first measuring device 110 and the second measuring device 120 jointly include a third incubation mechanism, which is used to incubate the first liquid containing at least the sample in the first reaction container 20 to produce a second liquid, and to incubate the third liquid containing at least the sample and the second type of reagent in the second reaction container 30 to produce a fourth liquid; the first measuring device 110 also includes a first measuring component 112, which is used to perform a coagulation test on the first sample prepared from at least the second liquid and the first type of reagent in the first reaction container 20; the second measuring device 120 also includes a second measuring component 122, which is used to perform a non-coagulation test on the second sample prepared from at least the fourth liquid in the second reaction container 30. The setting scheme here can be referred to the description in Example 5 and will not be described in detail here.

[0354] As other alternative implementations of the above-mentioned reagent dispensing device 160, reagent tray, and incubation mechanism setting scheme, reference may be made to the descriptions in Example 6 and Example 7, respectively, and no further details will be given here.

[0355] The sample analysis method provided in this embodiment includes an identification step, a coagulation measurement step, and a non-coagulation measurement step. The identification step includes the following steps:

[0356] Controlling the first identification component 300 to identify the sample container 40 loaded with the sample, and obtaining at least the test item of the sample in the sample container 40 according to the feedback information of the first identification component 300;

[0357] Controlling the second identification component 500 to identify the first reagent container and the second reagent container, and obtaining at least information about the first type of reagent in the first reagent container and information about the second type of reagent in the second reagent container based on feedback information from the second identification component 500;

[0358] The coagulation assay procedure includes the following steps:

[0359] Controlling the sample dispensing device 150 to absorb the sample from the sample container 40 and dispensing at least a portion of the absorbed sample into the first reaction container 20 ;

[0360] Controlling the reagent dispensing device 160 to absorb the first type of reagent from the first reagent container identified by the second identification component 500 and dispensing at least part of the absorbed first type of reagent into the first reaction container 20;

[0361] Controlling the first measuring device 110 to measure a coagulation test item on a first sample prepared by at least a sample and a first type of reagent in the first reaction container 20;

[0362] The non-coagulation assay procedure includes the following steps:

[0363] Controlling the sample dispensing device 150 to absorb the sample from the sample container 40 and dispensing at least a portion of the absorbed sample into the second reaction container 30 ;

[0364] Controlling the reagent dispensing device 160 to absorb the second type of reagent from the second reagent container identified by the second identification component 500 and dispensing at least part of the absorbed second type of reagent into the second reaction container 30;

[0365] The second measuring device 120 is controlled to measure a non-coagulation test item on the second sample prepared from at least the sample and the second type of reagent in the second reaction container 30 .

[0366] As an embodiment, the above-mentioned coagulation measurement step further includes the step of controlling the transfer device 140 to transfer the first reaction container 20 to which the sample has been distributed by the sample distribution device 150, after the sample distribution device 150 is controlled to draw the sample from the sample container 40 identified by the first identification component 300 and distribute at least part of the drawn sample to the first reaction container 20, and before the reagent distribution device 160 is controlled to draw the first type of reagent from the first reagent container identified by the second identification component 500 and distribute at least part of the drawn first type of reagent to the first reaction container 20, to the first measurement device 110.

[0367] As an embodiment, the above-mentioned non-coagulation measurement step further includes the step of controlling the transfer device 140 to transfer the second reaction container 30 to which the sample distribution device 150 has been allocated the sample after the sample distribution device 150 draws the sample from the sample container 40 identified by the first identification component 300 and distributes at least part of the absorbed sample to the second reaction container 30, and before controlling the reagent distribution device 160 to draw the second type of reagent from the second reagent container identified by the second identification component 500 and distribute at least part of the absorbed second type of reagent to the second reaction container 30: controlling the transfer device 140 to transfer the second reaction container 30 to which the sample has been distributed by the sample distribution device 150 to the second measurement device 120.

[0368] As an embodiment, the above-mentioned sample analysis method also includes: if it is determined based on the feedback information of the first identification component 300 that the test items to be tested of the sample include coagulation test items, then the coagulation measurement step is executed; if it is determined based on the feedback information of the first identification component 300 that the test items to be tested of the sample include non-coagulation test items, then the non-coagulation measurement step is executed.

[0369] The other parts of the sample analysis device 10 and the sample analysis method provided in this embodiment can be referred to in Embodiments 1 to 7 and will not be described in detail here.

[0370] The above description is only a preferred embodiment of the present application and does not limit the patent scope of the present application. All equivalent structural transformations made by using the contents of the present application description and drawings under the inventive concept of the present application, or direct / indirect application in other related technical fields are included in the patent protection scope of the present application.

Claims

1. A sample analysis device, characterized in that: include: A reaction container supply device, wherein the reaction container supply device is used to provide reaction containers; A sample dispensing device, the sample dispensing device is used to draw a sample from a sample container and distribute at least a portion of the drawn sample to the reaction container provided by the reaction container supply device; a reagent dispensing device, the reagent dispensing device being used to draw a reagent from a reagent container and to distribute at least a portion of the drawn reagent to the reaction container provided by the reaction container supply device; At least two measuring devices, the at least two measuring devices include a first measuring device and a second measuring device, the first measuring device is used to measure coagulation test items on the sample, and the second measuring device is used to measure non-coagulation test items on the sample; A transfer device, the transfer device is used to transfer the reaction container; a controller, the controller being configured to: control the transfer device to transfer the first reaction container provided by the reaction container supply device to the first measuring device, and control the first measuring device to measure a coagulation test item on a first sample made of at least a sample and a first type of reagent in the first reaction container; The controller is further configured to: control the transfer device to transfer the second reaction container provided by the reaction container supply device to the second measuring device, and control the second measuring device to measure a non-coagulation test item on a second sample made of at least a sample and a second type of reagent in the second reaction container; Wherein, any one of the reaction containers provided by the reaction container supply device can be selectively used as the first reaction container or the second reaction container.

2. The sample analysis device according to claim 1, wherein: The reaction container supply device has a single output channel for outputting the reaction containers, and any one of the reaction containers output from the single output channel can be selectively used as the first reaction container or the second reaction container; or, The reaction container supply device has at least two output channels for respectively outputting the reaction containers, and any reaction container output from each of the output channels can be selectively used as the first reaction container or the second reaction container.

3. The sample analysis device according to claim 1, wherein: The sample analysis device includes a single reaction container supply device, and the first reaction container and the second reaction container are reaction containers provided by the same single reaction container supply device.

4. The sample analysis device according to claim 1, wherein: The first reaction container and the second reaction container are the same reaction container provided by the same reaction container supply device; and / or, The first reaction container and the second reaction container are reaction containers of the same shape and size.

5. The sample analysis device according to claim 1, wherein: The controller is further configured to: first control the sample dispensing device to dispense the sample to the first reaction container provided by the reaction container supply device; and then control the transfer device to transfer the first reaction container loaded with the sample to the first assay device; The controller is further configured to: first control the sample dispensing device to dispense the sample to the second reaction container provided by the reaction container supply device; and then control the transfer device to transfer the second reaction container loaded with the sample to the second measuring device.

6. The sample analysis device according to claim 1, wherein: The sample analysis device further comprises a first identification component, the first identification component being used to identify the sample container before the sample container is aspirated; The controller is also configured to: According to the feedback information of the first identification component, at least obtaining the to-be-tested test item of the sample in the sample container; According to the test item of the sample to be tested, the reaction container provided by the reaction container supply device is selectively used as the first reaction container or the second reaction container.

7. The sample analysis device according to claim 6, wherein: The controller selectively uses the reaction container provided by the reaction container supply device as the first reaction container or the second reaction container according to the test item of the sample to be tested, including: When the test items to be tested of the sample include a coagulation test item, at least one reaction container provided by the reaction container supply device is used as the first reaction container, the sample dispensing device is controlled to absorb the sample from the sample container, and at least part of the absorbed sample is distributed to the first reaction container provided by the reaction container supply device; the transfer device is controlled to transfer the first reaction container loaded with the sample to the first measuring device, the reagent dispensing device is controlled to absorb the first type of reagent from the reagent container, and at least part of the absorbed first type of reagent is distributed to the first reaction container loaded with the sample in the first measuring device; the first measuring device is controlled to measure the first test sample made of at least the sample and the first type of reagent in the first reaction container; When the test items of the sample to be tested include non-coagulation test items, at least one reaction container provided by the reaction container supply device is used as the second reaction container, the sample dispensing device is controlled to absorb the sample from the sample container, and at least part of the absorbed sample is distributed to the second reaction container provided by the reaction container supply device; the transfer device is controlled to transfer the second reaction container loaded with the sample to the second measuring device, the reagent dispensing device is controlled to absorb the second type of reagent from the reagent container, and at least part of the absorbed second type of reagent is distributed to the second reaction container loaded with the sample in the second measuring device; the second measuring device is controlled to measure the second test sample made of at least the sample and the second type of reagent in the second reaction container; The controller is further configured to: according to feedback information from the first measuring device and / or the second measuring device, The analysis results of the samples are obtained.

8. The sample analysis device according to any one of claims 1 to 7, characterized in that: The reagent dispensing device includes a first reagent dispensing mechanism and a second reagent dispensing mechanism; The sample analysis device further includes a first reagent disk and a second reagent disk, wherein the first reagent disk is used to carry a first reagent container, wherein the first reagent container is loaded with a first type of reagent for measuring a coagulation test item, and the first reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container and dispense the absorbed first type of reagent into the first reaction container loaded with the sample; The second reagent disk is used to carry a second reagent container, the second reagent container is loaded with a second type of reagent for performing non-coagulation test items, and the second reagent dispensing mechanism is used to absorb the second type of reagent from the second reagent container and dispense the absorbed second type of reagent into the second reaction container loaded with the sample; The first measuring device comprises a first incubation mechanism and a first measuring component, wherein the first incubation mechanism is used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and the first measuring component is used to measure a coagulation detection item on the first sample prepared by at least the second liquid and the first type of reagent in the first reaction container; The second measuring device includes a second incubation mechanism and a second measuring component. The second incubation mechanism is used to incubate the third liquid in the second reaction container containing at least the sample and the second type of reagent to produce a fourth liquid. The second measuring component is used to measure non-coagulation detection items on the second sample made of at least the fourth liquid in the second reaction container.

9. The sample analysis device according to claim 8, wherein: The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the first transfer area, and control the transfer device to transfer the first reaction container from the first transfer area to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the first transfer area, and control the transfer device to transfer the second reaction container from the first transfer area to the second incubation mechanism.

10. The sample analysis device according to claim 9, wherein: The first transfer area includes a first transfer position, a second transfer position and a third transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the first intermediate transfer position, control the transfer device to transfer the first reaction container from the first intermediate transfer position to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with a sample, and the sample loaded is used for non-coagulation detection items from the reaction container supply device to the first transfer position, control the transfer device to transfer the second reaction container from the first transfer position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

11. The sample analysis device according to claim 9, wherein: The first transfer area includes a fourth transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the fourth transfer position, and control the transfer device to transfer the first reaction container from the fourth transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the fourth transfer position, and control the transfer device to transfer the second reaction container from the fourth transfer position to the second incubation mechanism.

12. The sample analysis device according to claim 9, wherein: The first transfer area includes a fifth transfer position and a sixth transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the fifth intermediate transfer position, control the transfer device to transfer the first reaction container from the fifth intermediate transfer position to the sixth intermediate transfer position, and control the transfer device to transfer the first reaction container from the sixth intermediate transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the fifth transfer position, control the transfer device to transfer the second reaction container from the fifth transfer position to the sixth transfer position, and control the transfer device to transfer the second reaction container from the sixth transfer position to the second incubation mechanism.

13. The sample analysis device according to claim 9, wherein: The first transfer area includes a second transfer position and a third transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

14. The sample analysis device according to claim 10, wherein: The transfer device comprises: a first transfer mechanism, wherein the first transfer mechanism is used to transfer the first The reaction container is transferred from the reaction container supply device to the first transfer area, and is used to transfer the second reaction container loaded with the sample from the reaction container supply device to the first transfer area under the control of the controller; a second transfer mechanism, the second transfer mechanism being used to transfer the first reaction container located at the first transfer area and used for measuring coagulation detection items to the first incubation mechanism under the control of the controller; A third transfer mechanism is used to transfer the second reaction container located in the first transfer area and used for performing non-coagulation detection items to the second incubation mechanism under the control of the controller.

15. The sample analysis device according to claim 14, wherein: The first transfer mechanism is used to transfer the reaction container loaded with the sample from the first reaction container supply device to the first intermediate transfer position under the control of the controller, and is used to transfer the second reaction container loaded with the sample from the reaction container supply device to the first intermediate transfer position under the control of the controller; The transfer device further includes a fourth transfer mechanism, which is used to transfer the first reaction container located at the first transfer position and used for measuring coagulation test items to the second transfer position under the control of the controller, and is used to transfer the second reaction container located at the first transfer position and used for measuring non-coagulation test items to the third transfer position under the control of the controller; The second transfer mechanism is used to transfer the first reaction container located at the second transfer position to the first incubation mechanism under the control of the controller; The third transfer mechanism is used to transfer the second reaction container located at the third transfer position to the second incubation mechanism under the control of the controller.

16. The sample analysis device according to claim 15, characterized in that: The fourth transfer mechanism is a track-type transfer mechanism, a turntable-type transfer mechanism, or a clamp-type transfer mechanism.

17. The sample analysis device according to any one of claims 1 to 7, characterized in that: The reagent dispensing device includes a third reagent dispensing mechanism; The sample analysis device further comprises a third reagent tray, the third reagent tray being used to carry a first reagent container and a second reagent container, the first reagent container being used to carry a first type of reagent for measuring coagulation detection items, and the second reagent container being used to carry a second type of reagent for measuring non-coagulation detection items; The third reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container and dispense the absorbed first type of reagent into the first reaction container loaded with the sample, and is used to absorb the second type of reagent from the second reagent container and dispense the absorbed second type of reagent into the second reaction container loaded with the sample; The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and being used to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid; The first measuring device further comprises a first measuring component, the first measuring component being used to measure a coagulation detection item on the first sample made of at least the second liquid and the first type of reagent in the first reaction container; The second measuring device further includes a second measuring component for measuring a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

18. The sample analysis device according to claim 17, wherein: The transfer device comprises: a fifth transfer mechanism, the fifth transfer mechanism being used to transfer the first reaction container loaded with the sample from the reaction container supply device to the second transfer area under the control of the controller, and being used to transfer the second reaction container loaded with the sample from the reaction container supply device to the second transfer area under the control of the controller; a sixth transfer mechanism, the sixth transfer mechanism being used to transfer the first reaction container located at the second transfer area to the third incubation mechanism under the control of the controller, and being used to transfer the second reaction container located at the second transfer area to the third incubation mechanism under the control of the controller; A seventh transfer mechanism, wherein the seventh transfer mechanism is used to transfer the first reaction container located at the third incubation mechanism and used for performing coagulation detection item determination to the first measurement component under the control of the controller, and is used to transfer the second reaction container located at the third incubation mechanism and used for performing non-coagulation detection item determination to the second measurement component under the control of the controller.

19. The sample analysis device according to claim 18, wherein: The second transfer area includes a seventh transfer position and an eighth transfer position; The fifth transfer mechanism is used to transfer the first reaction container loaded with the sample from the reaction container supply device to the seventh intermediate transfer position under the control of the controller, and is used to transfer the second reaction container loaded with the sample from the reaction container supply device to the seventh intermediate transfer position under the control of the controller; The transfer device further includes an eighth transfer mechanism, which is used to transfer the first reaction container located at the seventh transfer position to the eighth transfer position under the control of the controller, and is used to transfer the second reaction container located at the seventh transfer position to the eighth transfer position under the control of the controller; The sixth transfer mechanism is used to transfer the first reaction container located at the eighth transfer position to the third incubation mechanism under the control of the controller, and is used to transfer the second reaction container located at the eighth transfer position to the third incubation mechanism under the control of the controller.

20. The sample analysis device according to claim 18, wherein: The second transfer area includes a ninth transfer position and a tenth transfer position; The fifth transfer mechanism is used to transfer the first reaction container loaded with the sample from the reaction container supply device to the ninth transfer position under the control of the controller, and the sixth transfer mechanism is used to transfer the first reaction container located at the ninth transfer position to the third incubation mechanism under the control of the controller; The fifth transfer mechanism is also used to transfer the second reaction container loaded with the sample from the reaction container supply device to the tenth transfer position under the control of the controller, and the sixth transfer mechanism is also used to transfer the second reaction container located at the tenth transfer position to the third incubation mechanism under the control of the controller.

21. The sample analysis device according to any one of claims 1 to 7, characterized in that: The reagent dispensing device includes a fourth reagent dispensing mechanism and a fifth reagent dispensing mechanism; The sample analysis device further comprises a third reagent tray, the third reagent tray being used to carry a first reagent container and a second reagent container, the first reagent container being used to carry a first type of reagent for measuring coagulation detection items, and the second reagent container being used to carry a second type of reagent for measuring non-coagulation detection items; The fourth reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container of the third reagent disk and dispense at least part of the absorbed first type of reagent into the first reaction container loaded with the sample; The fifth reagent dispensing mechanism is used to absorb the second type of reagent from the second reagent container of the third reagent disk and dispense at least part of the absorbed second type of reagent into the second reaction container loaded with the sample; The first assay device and the second assay device jointly comprise a third incubation mechanism, the third incubation mechanism being used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and being used to incubate a third liquid containing at least a sample and the second type of reagent in the second reaction container to produce a fourth liquid; The first measuring device further comprises a first measuring component, the first measuring component being used to measure a coagulation detection item on the first sample made of at least the second liquid and the first type of reagent in the first reaction container; The second measuring device further includes a second measuring component for measuring a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

22. The sample analysis device according to any one of claims 1 to 7, characterized in that: The reagent dispensing device includes a sixth reagent dispensing mechanism and a seventh reagent dispensing mechanism; The sample analysis device further comprises a first reagent disk and a second reagent disk, wherein the first reagent disk is used to carry a first reagent container, and the first reagent container is loaded with a first type of reagent for measuring a coagulation test item; The second reagent disk is used to carry a second reagent container, and the second reagent container is loaded with a second type of reagent for performing non-coagulation test items; The sixth reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container of the first reagent disk and dispense at least part of the absorbed first type of reagent into the first reaction container loaded with the sample; The seventh reagent dispensing mechanism is used to absorb the second type of reagent from the second reagent container of the second reagent disk and dispense at least part of the absorbed second type of reagent into the second reaction container loaded with the sample; The first assay device and the second assay device jointly include a third incubation mechanism, the third incubation mechanism being used to incubate the first liquid containing at least the sample in the first reaction container to produce the second liquid, and to incubate the first liquid containing at least the sample in the first reaction container to produce the second liquid. The second reaction container at least contains a sample and a third liquid of the second type of reagent for incubation to produce a fourth liquid; The first measuring device further comprises a first measuring component, the first measuring component being used to measure a coagulation detection item on the first sample made of at least the second liquid and the first type of reagent in the first reaction container; The second measuring device further includes a second measuring component for measuring a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

23. The sample analysis device according to any one of claims 1 to 7, characterized in that: The non-coagulation test items measured by the second measuring device are immunological test items or biochemical test items.

24. A sample analysis device, characterized in that: include: a first identification component, the first identification component being used to identify a sample container loaded with a sample; a second identification component, the second identification component is used to identify a reagent container, the reagent container includes a first reagent container and a second reagent container, the first reagent container is loaded with a first type of reagent, and the second reagent container is loaded with a second type of reagent; A sample dispensing device, the sample dispensing device is used to draw a sample from the sample container identified by the first identification component, and distribute at least a portion of the drawn sample to a reaction container; a reagent dispensing device, the reagent dispensing device being used to draw the first type of reagent from the first reagent container identified by the second identification component, and dispensing at least part of the drawn first type of reagent to the reaction container; and being used to draw the second type of reagent from the second reagent container identified by the second identification component, and dispensing at least part of the drawn second type of reagent to the reaction container; At least two measuring devices, the at least two measuring devices include a first measuring device and a second measuring device, the first measuring device is used to measure coagulation test items on the sample, and the second measuring device is used to measure non-coagulation test items on the sample; A controller, the controller being configured to: obtain at least the to-be-tested test item of the sample in the sample container according to the feedback information of the first identification component; and obtain at least the information of the reagent in the reagent container according to the feedback information of the second identification component; The controller is further configured to: control the sample dispensing device to draw a sample from the sample container identified by the first identification component, and distribute at least part of the drawn sample to the first reaction container, control the reagent dispensing device to draw the first type of reagent from the first reagent container identified by the second identification component and distribute it to the first reaction container, and control the first measuring device to measure a coagulation test item on a first test specimen made of at least the sample and the first type of reagent in the first reaction container; The controller is further configured to: control the sample dispensing device to draw a sample from the sample container identified by the first identification component, and to distribute at least part of the drawn sample to the second reaction container, and to control the reagent dispensing device The second type of reagent is drawn from the second reagent container identified by the second identification component and distributed to the second reaction container, and the second measuring device is controlled to measure a non-coagulation test item on a second sample made of at least a sample and the second type of reagent in the second reaction container.

25. The sample analysis device according to claim 24, characterized in that: The first reaction container and the second reaction container are the same reaction container; and / or, The first reaction container and the second reaction container are reaction containers of the same shape and size.

26. The sample analysis device according to claim 24, wherein: The sample analysis device further comprises a transfer device, and the transfer device is used to transfer the reaction container; The controller is also configured to: When the test items of the sample to be tested include a coagulation test item, at least one reaction container is used as the first reaction container, the sample dispensing device is controlled to absorb the sample from the sample container, and at least part of the absorbed sample is distributed to the first reaction container; the transfer device is controlled to transfer the first reaction container loaded with the sample to the first measuring device, the reagent dispensing device is controlled to absorb the first type of reagent from the first reagent container, and at least part of the absorbed first type of reagent is distributed to the first reaction container loaded with the sample in the first measuring device; the first measuring device is controlled to measure the first test sample made of at least the sample and the first type of reagent in the first reaction container; When the test items of the sample to be tested include non-coagulation test items, at least one reaction container is used as the second reaction container, the sample dispensing device is controlled to absorb the sample from the sample container, and at least part of the absorbed sample is distributed to the second reaction container; the transfer device is controlled to transfer the second reaction container loaded with the sample to the second measuring device, the reagent dispensing device is controlled to absorb the second type of reagent from the second reagent container, and at least part of the absorbed second type of reagent is distributed to the second reaction container loaded with the sample in the second measuring device; the second measuring device is controlled to measure the second test sample made of at least the sample and the second type of reagent in the second reaction container; The measurement result of the sample is analyzed and obtained according to the feedback information of the first measurement device and / or the second measurement device.

27. The sample analysis device according to any one of claims 24 to 26, characterized in that: The reagent dispensing device includes a first reagent dispensing mechanism and a second reagent dispensing mechanism; The sample analysis device further includes a first reagent tray and a second reagent tray, wherein the first reagent tray is used to carry the first reagent container, and the first reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container and dispense at least part of the absorbed first type of reagent into the first reaction container loaded with the sample; The second reagent tray is used to carry the second reagent container, and the second reagent dispensing mechanism is used to absorb the second type of reagent from the second reagent container and dispense at least part of the absorbed second type of reagent into the sample container. in the second reaction container; The first measuring device comprises a first incubation mechanism and a first measuring component, wherein the first incubation mechanism is used to incubate a first liquid containing at least a sample in the first reaction container to produce a second liquid, and the first measuring component is used to measure a coagulation detection item on the first sample prepared by at least the second liquid and the first type of reagent in the first reaction container; The second measuring device includes a second incubation mechanism and a second measuring component. The second incubation mechanism is used to incubate the third liquid in the second reaction container containing at least the sample and the second type of reagent to produce a fourth liquid. The second measuring component is used to measure non-coagulation detection items on the second sample made of at least the fourth liquid in the second reaction container.

28. The sample analysis device according to claim 27, wherein: The sample analysis device further comprises a transfer device, and the transfer device is used to transfer the reaction container; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the reaction container supply device to the first transfer area, and control the transfer device to transfer the first reaction container from the first transfer area to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the reaction container supply device to the first transfer area, and control the transfer device to transfer the second reaction container from the first transfer area to the second incubation mechanism.

29. The sample analysis device according to claim 28, wherein: The first transfer area includes a first transfer position, a second transfer position and a third transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the sample loading position to the first intermediate transfer position, control the transfer device to transfer the first reaction container from the first intermediate transfer position to the second intermediate transfer position, and control the transfer device to transfer the first reaction container from the second intermediate transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with a sample used for non-coagulation detection items from the sample loading position to the first transfer position, control the transfer device to transfer the second reaction container from the first transfer position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

30. The sample analysis device according to claim 28, wherein: The first transfer area includes a fourth transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the sample loading position to the fourth transfer position, and control the transfer device to transfer the first reaction container from the fourth transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the sample loading position to the fourth transfer position, and control the transfer device to transfer the second reaction container from the fourth transfer position to the second incubation mechanism.

31. The sample analysis device according to claim 28, wherein: The first transfer area includes a fifth transfer position and a sixth transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the sample loading position to the fifth intermediate transfer position, control the transfer device to transfer the first reaction container from the fifth intermediate transfer position to the sixth intermediate transfer position, and control the transfer device to transfer the first reaction container from the sixth intermediate transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with a sample, and the sample loaded is used for non-coagulation detection items from the sample loading position to the fifth transfer position, control the transfer device to transfer the second reaction container from the fifth transfer position to the sixth transfer position, and control the transfer device to transfer the second reaction container from the sixth transfer position to the second incubation mechanism.

32. The sample analysis device according to claim 28, wherein: The first transfer area includes a second transfer position and a third transfer position; The controller is configured to: control the transfer device to transfer the first reaction container loaded with a sample for measuring a coagulation test item from the sample loading position to the second transfer position, and control the transfer device to transfer the first reaction container from the second transfer position to the first incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with samples and the loaded samples are used for non-coagulation detection items from the sample loading position to the third transfer position, and control the transfer device to transfer the second reaction container from the third transfer position to the second incubation mechanism.

33. The sample analysis device according to any one of claims 24 to 26, characterized in that: The reagent dispensing device includes a third reagent dispensing mechanism; The sample analysis device further includes a third reagent tray, and the third reagent tray is used to carry the first reagent container and the second reagent container; The third reagent dispensing mechanism is used to absorb the first type of reagent from the first reagent container and dispense at least part of the absorbed first type of reagent into the first reaction container loaded with the sample, and is used to absorb the second type of reagent from the second reagent container and dispense at least part of the absorbed second type of reagent into the second reaction container loaded with the sample; The first assay device and the second assay device jointly include a third incubation mechanism, the third incubation mechanism being used to incubate the first liquid containing at least the sample in the first reaction container to produce the second liquid, and to incubate the first liquid containing at least the sample in the first reaction container to produce the second liquid. The second reaction container at least contains a sample and a third liquid of the second type of reagent for incubation to produce a fourth liquid; The first measuring device further comprises a first measuring component, the first measuring component being used to measure a coagulation detection item on the first sample made of at least the second liquid and the first type of reagent in the first reaction container; The second measuring device further includes a second measuring component for measuring a non-coagulation test item on the second sample made of at least the fourth liquid in the second reaction container.

34. The sample analysis device according to claim 32, wherein: The sample analysis device further comprises a transfer device, and the transfer device is used to transfer the reaction container; The controller is further configured to: control the transfer device to transfer the first reaction container loaded with the sample from the sample loading position to the seventh transfer position, control the transfer device to transfer the first reaction container located at the seventh transfer position to the eighth transfer position, and control the transfer device to transfer the first reaction container located at the eighth transfer position to the third incubation mechanism; The controller is also configured to: control the transfer device to transfer the second reaction container loaded with the sample from the sample loading position to the seventh transfer position, control the transfer device to transfer the second reaction container located at the seventh transfer position to the eighth transfer position, and control the transfer device to transfer the second reaction container located at the eighth transfer position to the third incubation mechanism.

35. The sample analysis device according to any one of claims 24 to 26, characterized in that: The non-coagulation test items measured by the second measuring device are immunological test items or biochemical test items.

36. A sample analysis method, characterized in that: It includes a coagulation measurement step and a non-coagulation measurement step, and the coagulation measurement step includes the following steps: Controlling the reaction container supply device to provide a first reaction container; Controlling the sample dispensing device to draw the sample from the sample container, and dispensing at least a portion of the drawn sample into the first reaction container; Controlling the reagent dispensing device to absorb the first type of reagent from the first reagent container, and dispensing at least part of the absorbed first type of reagent into the first reaction container; Controlling the first measuring device to measure a coagulation test item on a first sample made of at least a sample and the first type of reagent in the first reaction container; The non-coagulation determination step comprises the following steps: Controlling the reaction container supply device to provide a second reaction container; Controlling the sample dispensing device to draw the sample from the sample container, and dispensing at least a portion of the drawn sample into the second reaction container; Control the reagent dispensing device to absorb the second type of reagent from the second reagent container, and absorb at least part of the second type of reagent Dispensing into the second reaction container; Controlling the second measuring device to measure a non-coagulation test item on a second test specimen made of at least the sample and the second type of reagent in the second reaction container; Wherein, any one of the reaction containers provided by the reaction container supply device can be selectively used as the first reaction container or the second reaction container.

37. The sample analysis method according to claim 36, characterized in that: After the sample dispensing device is controlled to draw a sample from the sample container and distribute at least part of the drawn sample to the first reaction container, and before the reagent dispensing device is controlled to draw a first type of reagent from the first reagent container and distribute at least part of the drawn first type of reagent to the first reaction container, the coagulation measurement step further includes the steps of: controlling the transfer device to transfer the first reaction container provided by the reaction container supply device and after the sample is distributed by the sample dispensing device to the first measurement device; and / or, The non-coagulation measurement step further includes the step of controlling the transfer device to transfer the second reaction container provided by the reaction container supply device and after the sample dispensing device is controlled to draw the sample from the sample container and distribute at least part of the drawn sample to the second reaction container, and before the reagent dispensing device is controlled to draw the second type of reagent from the second reagent container and distribute at least part of the drawn second type of reagent to the second reaction container, to the second measurement device.

38. The sample analysis method according to claim 36 or 37, characterized in that: The sample analysis method further includes an identification step before the coagulation measurement step and / or the non-coagulation measurement step, and the identification step includes: controlling a first identification component to identify the sample container; obtaining at least the test items to be tested of the sample in the sample container according to feedback information from the first identification component; when the test items to be tested of the sample include coagulation test items, executing the coagulation measurement step; when the test items to be tested of the sample include non-coagulation test items, executing the non-coagulation measurement step.

39. A sample analysis method, characterized in that: It includes an identification step, a coagulation measurement step and a non-coagulation measurement step, wherein the identification step includes the following steps: Controlling the first identification component to identify the sample container loaded with the sample, and obtaining at least the to-be-tested test item of the sample in the sample container according to the feedback information of the first identification component; Controlling the second identification component to respectively identify the first reagent container and the second reagent container, and obtaining at least information about the first type of reagent in the first reagent container and information about the second type of reagent in the second reagent container according to feedback information from the second identification component; The coagulation determination step comprises the following steps: Controlling the sample distributing device to absorb the sample from the sample container identified by the first identification component, and distributing at least part of the absorbed sample to the first reaction container; Control the reagent dispensing device to draw the first reagent from the first reagent container identified by the second identification component. a first type of reagent, and dispensing at least a portion of the first type of reagent sucked into the first reaction container; Controlling the first measuring device to measure a coagulation test item on a first sample made of at least a sample and the first type of reagent in the first reaction container; The non-coagulation determination step comprises the following steps: Controlling the sample dispensing device to draw a sample from the sample container identified by the first identification component, and dispensing at least a portion of the drawn sample to a second reaction container; Controlling the reagent dispensing device to absorb the second type of reagent from the second reagent container identified by the second identification component, and dispensing at least part of the absorbed second type of reagent into the second reaction container; The second measuring device is controlled to measure a non-coagulation test item on a second sample prepared from at least a sample and a second type of reagent in the second reaction container.

40. The control method of the sample analysis device according to claim 39, characterized in that: After the sample dispensing device is controlled to draw the sample from the sample container identified by the first identification component and distribute at least part of the drawn sample to the first reaction container, and before the reagent dispensing device is controlled to draw the first type of reagent from the first reagent container identified by the second identification component and distribute at least part of the drawn first type of reagent to the first reaction container, the coagulation measurement step further includes the steps of: controlling the transfer device to transfer the first reaction container to which the sample is distributed by the sample dispensing device to the first measurement device; and / or, The non-coagulation measurement step further includes the step of controlling the transfer device to transfer the second reaction container to which the sample has been allocated by the sample allocation device, after the sample allocation device is controlled to draw the sample from the sample container identified by the first identification component and allocate at least part of the drawn sample to the second reaction container, and before the reagent allocation device is controlled to draw the second type of reagent from the second reagent container identified by the second identification component and allocate at least part of the drawn second type of reagent to the second reaction container: controlling the transfer device to transfer the second reaction container to which the sample has been allocated by the sample allocation device, to the second measurement device.

41. The control method of the sample analysis device according to claim 39 or 40, characterized in that: The sample analysis method further comprises: if it is determined that the to-be-tested test items of the sample include a coagulation test item according to the feedback information of the first identification component, then executing the coagulation determination step; If it is determined based on the feedback information of the first identification component that the to-be-tested test items of the sample include non-coagulation test items, the non-coagulation determination step is performed.

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