Combined inhibitor for flotation separation of copper-zinc sulfide ore and application of combined inhibitor

Abstract

The invention provides a combined inhibitor for flotation separation of copper-zinc sulfide ore and application of the combined inhibitor. The combined inhibitor comprises sodium tartrate and zinc sulfate. According to the application of the combined inhibitor for flotation separation of the copper-zinc sulfide ore in flotation separation of the copper-zinc sulfide ore, the application comprises the following steps that firstly, after a copper-zinc sulfide ore sample is crushed and ground, pulp mixing is conducted, and copper-zinc sulfide ore pulp is obtained; secondly, a pH regulator, a combined inhibitor, a roughing collecting agent and a foaming agent are sequentially added into the copper-zinc sulfide ore pulp in the first step, and roughing copper concentrate and roughing zinc concentrate are obtained; and thirdly, a combined inhibitor is added into the roughed copper concentrate obtained in the second step for first-time concentration, then the combined inhibitor is added for second-time concentration, and final copper concentrate is obtained. According to the method, the content of zinc in the copper concentrate is greatly reduced while the copper recovery rate is guaranteed, and the recovery rate of copper and zinc resources is effectively increased. Compared with a single zinc sulfate inhibitor or a sodium tartrate inhibitor, the copper-zinc separation efficiency is high, and the dosage of the combined inhibitor is greatly reduced.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of sulfide ore flotation recovery, and relates to a copper-zinc sulfide ore, in particular to a combined inhibitor for flotation separation of a copper-zinc sulfide ore and application thereof. BACKGROUND

[0002] Copper and zinc mainly come from copper-zinc sulfide ores. In different types of copper-zinc ores, copper sulfide minerals and zinc sulfide minerals often closely coexist and are wrapped in each other. Flotation is the most commonly used method for separating copper-zinc sulfide ores. However, the surface of copper sulfide minerals is prone to oxidation and dissolution during grinding and flotation, generating a large amount of copper ions. These copper ions are adsorbed on the surface of sphalerite through ion exchange, forming an activated film of CuS-like (CuS), which significantly increases the hydrophobicity of the sphalerite surface and makes the floatability of the sphalerite highly similar to that of the copper sulfide minerals, resulting in a significant increase in the difficulty of flotation separation of the two. x

[0003] In order to achieve effective separation of copper-zinc sulfide ores, inhibitors are often added during flotation to selectively weaken the floatability of sphalerite. Inhibitors are mainly divided into two categories: inorganic and organic. Common inorganic inhibitors include cyanide, water-soluble zinc salt, sodium sulfide, etc. Cyanide has good inhibitory effect because it can form a hydrophilic film on the surface of sphalerite, but it is highly toxic and has been rarely used; sodium sulfide has poor selectivity, is easily oxidized and loses effectiveness, and its dosage needs to be strictly controlled, otherwise it will have a strong inhibitory effect on chalcopyrite and other copper sulfide minerals; water-soluble zinc salt is the most commonly used inhibitor in industry, which is often used in combination with lime or sodium hydroxide to form zincate anions (such as [Zn(OH)4] 2- ) under alkaline conditions, which are adsorbed on the surface of sphalerite, reducing the adsorption of collectors and thus reducing the floatability. However, water-soluble zinc salt has the disadvantages of narrow effective inhibition pH range and poor selectivity; and a large amount of addition is often required to enhance the inhibitory effect, resulting in a significant increase in reagent cost. Organic inhibitors (such as starch, humic acid, mercaptoacetic acid, salicylic acid, etc.) mainly achieve selective inhibition of sphalerite by competing with collectors for adsorption or by complexation reaction to eliminate the activation effect of copper ions in the ore slurry, but they also face problems such as large addition amount, strict use conditions, high reagent cost, and poor inhibitory durability, which limit their industrial application.

[0004] To overcome the limitations of the above single inhibitors, the development and application of combined inhibitors has become an important development direction for achieving efficient flotation separation of copper-zinc sulfide ores. Therefore, in view of the characteristics of copper-zinc sulfide ores, the development of new, efficient, low-toxicity and environmentally friendly combined inhibitors is of urgent technical need and has broad industrial application prospects for breaking through the technical bottleneck of flotation separation of complex copper-zinc sulfide ores, improving separation efficiency, reducing reagent consumption and environmental risk. SUMMARY

[0005] ​In view of the deficiencies of the prior art, the present application aims to provide a combined inhibitor for copper-zinc sulfide ore flotation separation and application thereof, so as to solve the technical problem of low copper-zinc separation efficiency in the prior art.

[0006] In order to solve the above technical problems, the present application adopts the following technical solutions: The combined inhibitor for copper-zinc sulfide ore flotation separation comprises sodium tartrate and zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1: (0.5-2.5).

[0007] The present application also has the following technical features: The mass ratio of sodium tartrate to zinc sulfate is 1:1.

[0008] The present application also protects the application of the combined inhibitor for copper-zinc sulfide ore flotation separation as described above to copper-zinc sulfide ore flotation separation.

[0009] The application comprises the following steps: Step one, the copper-zinc sulfide ore sample is crushed and ground to a certain fineness, and then is slurried to obtain a copper-zinc sulfide ore slurry; Step two, a pH adjusting agent is added to the copper-zinc sulfide ore slurry in step one to adjust the pH of the copper-zinc sulfide ore slurry to 6-11, and then a combined inhibitor, a roughing collector and a foaming agent are sequentially added for roughing to obtain a roughing copper concentrate and a roughing zinc concentrate; Step three, the combined inhibitor is added to the roughing copper concentrate in step two for first cleaning, and the combined inhibitor is further added to the first cleaned roughing copper concentrate for second cleaning to obtain a final copper concentrate.

[0010] Specifically, in step one, the copper-zinc sulfide ore sample is ground to a fineness of -0.074 mm, and the copper-zinc sulfide ore sample with a fineness of -0.074 mm accounts for 50wt%-90wt% of the copper-zinc sulfide ore sample.

[0011] Specifically, in step one of the embodiment, the mass percentage of the copper-zinc sulfide ore slurry is 30wt%-45wt%.

[0012] Specifically, in step two, the roughing collector is one or a combination of more than one of ethyl xanthate, butyl xanthate, butyl ammonium black medicine and ethylthiuram.

[0013] Specifically, in step two, the foaming agent is one or a combination of more than one of No. 2 oil, pine alcohol oil and methyl isobutyl carbinol.

[0014] Specifically, in step two, the sodium tartrate in the combined inhibitor is added in an amount of 100-400 g / t, the zinc sulfate in the combined inhibitor is added in an amount of 40-300 g / t, the roughing collector is added in an amount of 10-100 g / t, and the frother is added in an amount of 10-60 g / t.

[0015] Specifically, in the first cleaning in step three, the sodium tartrate in the combined inhibitor is added in an amount of 50-200 g / t, and the zinc sulfate in the combined inhibitor is added in an amount of 20-150 g / t.

[0016] Specifically, in the second cleaning in step three, the sodium tartrate in the combined inhibitor is added in an amount of 25-100 g / t, and the zinc sulfate in the combined inhibitor is added in an amount of 10-75 g / t.

[0017] Compared with the prior art, the present application has the following technical effects: (Ⅰ) The combined inhibitor for copper-zinc sulfide ore flotation separation and its application provided by the present application can greatly reduce the content of zinc in the copper concentrate while ensuring the copper recovery rate, and effectively improves the recovery and utilization rate of copper-zinc resources. Compared with single zinc sulfate inhibitor or sodium tartrate inhibitor, the copper-zinc separation efficiency is high, and the amount of combined inhibitor is greatly reduced.

[0018] (Ⅱ) The combined inhibitor for copper-zinc sulfide ore flotation separation and its application provided by the present application can weaken the interaction between copper-zinc sulfide ore by using the cooperation of organic and inorganic inhibitors, and achieve deep inhibition of copper-activated sphalerite. Not only can the deactivation and hindering of the adsorption capacity of the collector on copper-activated sphalerite be significantly enhanced on the basis of the traditional inhibition system, but also the selectivity and adaptability of copper-zinc flotation can be significantly improved, which better meets the needs of the flotation production site.

[0019] (Ⅲ) The combined inhibitor for copper-zinc sulfide ore flotation separation and its application provided by the present application uses reagent which is a conventional chemical for mineral processing, and has low cost and environmental friendliness. The process flow has strong adaptability, which helps to reduce the amount and cost of reagent, realizes green and efficient flotation recovery of copper-zinc resources, and has wide industrial application prospect.

[0020] (Ⅳ) The combined inhibitor for copper-zinc sulfide ore flotation separation provided by the present application is used to inhibit copper ion-activated sphalerite, and realizes the flotation separation of chalcopyrite, chalcocite and other sulfide copper minerals and sphalerite. DETAILED DESCRIPTION

[0021] It should be noted that the equipment and materials used in the present application, if not specifically stated, are known equipment and materials in the prior art.

[0022] The application provides a combined inhibitor for flotation separation of copper-zinc sulfide ore, which comprises a tartrate and a water-soluble zinc salt.

[0023] In the application, the pH regulator is hydrochloric acid or sodium hydroxide.

[0024] In accordance with the above technical solution, the following specific embodiments of the application are given, and it should be noted that the application is not limited to the following specific embodiments, and any equivalent transformation based on the technical solution of the application falls within the protection scope of the application.

[0025] Embodiment 1 The embodiment provides a combined inhibitor for flotation separation of copper-zinc sulfide ore, which comprises a tartrate and a water-soluble zinc salt.

[0026] In the embodiment, the tartrate is sodium tartrate, and the water-soluble zinc salt is zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1:0.6.

[0027] The embodiment also provides an application of the combined inhibitor for flotation separation of copper-zinc sulfide ore, and the application comprises the following steps. Step one, a copper-zinc sulfide ore sample with a copper grade of 3.06% and a zinc grade of 5.13% is crushed and ground, and the copper-zinc sulfide ore sample is ground to a fineness of-0.074 mm, so that the copper-zinc sulfide ore sample with a fineness of-0.074 mm accounts for 80wt% of the total copper-zinc sulfide ore sample, and then the copper-zinc sulfide ore sample is placed in a flotation tank for pulp conditioning to obtain a copper-zinc sulfide ore slurry with a mass percentage of 35wt%; Step two, a pH regulator is added to the copper-zinc sulfide ore slurry in step one to adjust the pH to 9.0, and stirred for 5 min, then the combined inhibitor (sodium tartrate 200g / t and zinc sulfate 120g / t) is added, stirred for 3 min, then the roughing collector (butyl xanthate and ethylthiuramium acetate, 60g / t in total, and the mass addition ratio of butyl xanthate to ethylthiuramium acetate is 2:1) is added, stirred for 2 min, then the frother (No. 2 oil 30g / t) is added, stirred for 2 min, and then air flotation is carried out, and the froth is scraped for 5 min to obtain a roughing copper concentrate and a roughing zinc concentrate. Step three, the combined depressant (sodium tartrate 100 g / t, zinc sulfate 60 g / t) is added to the rough copper concentrate in step two, and stirred for 3 min, then the first cleaning is carried out, and then the combined depressant (sodium tartrate 50 g / t, zinc sulfate 30 g / t) is added to the rough copper concentrate after the first cleaning, and stirred for 2 min, then the second cleaning is carried out, and finally the copper concentrate with copper grade of 24.86%, copper recovery rate of 94.15% and zinc content of 1.64% is obtained.

[0028] Example 2: The embodiment gives a combined depressant for the flotation separation of copper-zinc sulfide ore, which comprises a tartrate and a water-soluble zinc salt.

[0029] In this embodiment, the tartrate is sodium tartrate, the water-soluble zinc salt is zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1:0.75.

[0030] The embodiment also gives the application of the combined depressant for the flotation separation of copper-zinc sulfide ore; the application comprises the following steps: Step one, the copper-zinc sulfide ore sample with copper grade of 3.06% and zinc grade of 5.13% is crushed and ground, and the grinding is carried out to the copper-zinc sulfide ore sample with fineness of-0.074 mm, so that the copper-zinc sulfide ore sample with fineness of-0.074 mm accounts for 80wt% of the total copper-zinc sulfide ore sample, and then the copper-zinc sulfide ore sample is placed in a flotation tank for pulp conditioning to obtain a copper-zinc sulfide ore slurry with mass percentage of 35%; Step two, the pH adjusting agent is added to the copper-zinc sulfide ore slurry in step one, and the pH is adjusted to 9.0, and stirred for 5 min, then the combined depressant (sodium tartrate 400 g / t, zinc sulfate 300 g / t) is added, stirred for 3 min, then the roughing collector (butyl xanthate and ethylthiuram sodium 60 g / t, mass ratio of butyl xanthate to ethylthiuram sodium is 2:1) is added, stirred for 2 min, then the frother (No. 2 oil 30 g / t) is added, stirred for 2 min, and then air flotation is carried out, and the rough copper concentrate and the rough zinc concentrate are obtained after scraping the froth for 5 min; Step three, the combined depressant (sodium tartrate 200 g / t, zinc sulfate 150 g / t) is added to the rough copper concentrate in step two, and stirred for 3 min, then the first cleaning is carried out, and then the combined depressant (sodium tartrate 100 g / t, zinc sulfate 75 g / t) is added to the rough copper concentrate after the first cleaning, and stirred for 2 min, then the second cleaning is carried out, and finally the copper concentrate with copper grade of 26.64%, copper recovery rate of 87.54% and zinc content of 1.13% is obtained.

[0031] Example 3: The embodiment gives a combined depressant for the flotation separation of copper-zinc sulfide ore, which comprises a tartrate and a water-soluble zinc salt.

[0032] In this embodiment, the tartrate is sodium tartrate, the water-soluble zinc salt is zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1:0.6.

[0033] This embodiment also provides an application of the combined inhibitor for the flotation separation of copper-zinc sulfide ore; the application comprises the following steps: Step one, a copper-zinc sulfide ore sample with a copper grade of 3.06% and a zinc grade of 5.13% is crushed and ground, and the copper-zinc sulfide ore sample is ground to a fineness of -0.074 mm, so that the copper-zinc sulfide ore sample with a fineness of -0.074 mm accounts for 85wt% of the total copper-zinc sulfide ore sample, and then the copper-zinc sulfide ore sample is placed in a flotation tank for pulp conditioning to obtain a copper-zinc sulfide ore slurry with a mass percentage of 35%; Step two, a pH adjusting agent is added to the copper-zinc sulfide ore slurry in step one, the pH is adjusted to 7.0, and stirring is performed for 5 min, then the combined inhibitor (sodium tartrate 200 g / t and zinc sulfate 120 g / t) is added, stirring is performed for 3 min, then the roughing collector (butyl xanthate and ethylthiuram 60 g / t, and the addition ratio of butyl xanthate to ethylthiuram is 2:1) is added, stirring is performed for 2 min, then the frother (No. 2 oil 30 g / t) is added, stirring is performed for 2 min, and then aeration flotation is performed, and scraping is performed for 5 min to obtain a roughing copper concentrate and a roughing zinc concentrate; Step three, the combined inhibitor (sodium tartrate 100 g / t and zinc sulfate 60 g / t) is added to the roughing copper concentrate in step two, stirring is performed for 3 min, and then the first cleaning is performed, then the combined inhibitor (sodium tartrate 50 g / t and zinc sulfate 30 g / t) is added to the roughing copper concentrate after the first cleaning, stirring is performed for 2 min, and then the second cleaning is performed, and finally a copper concentrate with a copper grade of 23.39%, a copper recovery rate of 95.72%, and a zinc content of 1.87% is obtained.

[0034] Embodiment 4: This embodiment provides a combined inhibitor for the flotation separation of copper-zinc sulfide ore, which comprises a tartrate and a water-soluble zinc salt.

[0035] In this embodiment, the tartrate is sodium tartrate, the water-soluble zinc salt is zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1:1.

[0036] This embodiment also provides an application of the combined inhibitor for the flotation separation of copper-zinc sulfide ore; the application comprises the following steps: Step one, a copper-zinc sulfide ore sample with a copper grade of 3.06% and a zinc grade of 5.13% is crushed and ground, and the copper-zinc sulfide ore sample is ground to a fineness of -0.074 mm, so that the copper-zinc sulfide ore sample with a fineness of -0.074 mm accounts for 80wt% of the total copper-zinc sulfide ore sample, and then the copper-zinc sulfide ore sample is placed in a flotation tank for pulp conditioning to obtain a copper-zinc sulfide ore slurry with a mass percentage of 35%; Step two, add pH regulator to the copper-zinc sulphide ore slurry in step one, adjust pH to 9.0, stir for 5 min, then add combined depressant (sodium tartrate 200 g / t, zinc sulfate 200 g / t), stir for 3 min, then add roughing collector (butyl xanthate 60 g / t), stir for 2 min, then add frother (No. 2 oil 30 g / t), stir for 2 min, then air flotation, scrape froth for 5 min, to obtain roughing copper concentrate and roughing zinc concentrate; Step three, add combined depressant (sodium tartrate 100 g / t, zinc sulfate 100 g / t) to the roughing copper concentrate in step two, stir for 3 min, then first cleaning, then add combined depressant (sodium tartrate 50 g / t, zinc sulfate 50 g / t) to the roughing copper concentrate after first cleaning, stir for 2 min, then second cleaning, finally obtain copper concentrate with copper grade of 26.75%, copper recovery of 93.21%, and zinc content of 1.02%.

[0037] Example 5: The present embodiment provides a combined depressant for copper-zinc sulphide ore flotation separation, which comprises tartrate and water-soluble zinc salt.

[0038] In the present embodiment, the tartrate is sodium tartrate, the water-soluble zinc salt is zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1:2.

[0039] The present embodiment also provides an application of the combined depressant for copper-zinc sulphide ore flotation separation; the application comprises the following steps: Step one, crush and grind the copper-zinc sulphide ore sample with copper grade of 3.06% and zinc grade of 5.13%, grind to a fineness of -0.074 mm copper-zinc sulphide ore sample, so that the -0.074 mm copper-zinc sulphide ore sample accounts for 80 wt% of the total copper-zinc sulphide ore sample, then perform slurry conditioning in a flotation cell to obtain a copper-zinc sulphide ore slurry with a mass percentage of 35%; Step two, add pH regulator to the copper-zinc sulphide ore slurry in step one, adjust pH to 9.0, stir for 5 min, then add combined depressant (sodium tartrate 100 g / t, zinc sulfate 200 g / t), stir for 3 min, then add roughing collector (butyl xanthate 60 g / t), stir for 2 min, then add frother (No. 2 oil 30 g / t), stir for 2 min, then air flotation, scrape froth for 5 min, to obtain roughing copper concentrate and roughing zinc concentrate; Step three, to the rough copper concentrate in step two, add the combined depressant (sodium tartrate 50 g / t, zinc sulfate 100 g / t) again, stir for 3 min, then conduct the first cleaning, and then to the rough copper concentrate after the first cleaning, add the combined depressant (sodium tartrate 25 g / t, zinc sulfate 50 g / t) again, stir for 2 min, then conduct the second cleaning, finally obtain the copper concentrate with copper grade of 22.16%, copper recovery rate of 92.74%, and zinc content of 1.13%.

[0040] Comparative example 1: This comparative example gives a depressant for the flotation separation of copper-zinc sulfide ore, and the depressant is sodium tartrate.

[0041] In this comparative example, the sodium tartrate is sodium tartrate.

[0042] This comparative example also gives the application of the depressant for the flotation separation of copper-zinc sulfide ore; the application includes the following steps: Step one, crush and grind the copper-zinc sulfide ore sample with copper grade of 3.06% and zinc grade of 5.13%, grind the copper-zinc sulfide ore sample to a fineness of -0.074 mm, so that the copper-zinc sulfide ore sample with a fineness of -0.074 mm accounts for 80 wt% of the total copper-zinc sulfide ore sample, then place it in a flotation cell for slurry conditioning, and obtain a copper-zinc sulfide ore slurry with a mass percentage of 35%; Step two, add a pH adjuster to the copper-zinc sulfide ore slurry in step one, adjust the pH to 9.0, stir for 5 min, then add sodium tartrate 200 g / t, stir for 3 min, then add a roughing collector (butyl xanthate 60 g / t), stir for 2 min, then add a frother (No. 2 oil 30 g / t), stir for 2 min, then air float, and scrape the froth for 5 min, to obtain a rough copper concentrate and a rough zinc concentrate; Step three, to the rough copper concentrate in step two, add sodium tartrate 100 g / t again, stir for 3 min, then conduct the first cleaning, and then to the rough copper concentrate after the first cleaning, add sodium tartrate 50 g / t again, stir for 2 min, then conduct the second cleaning, finally obtain the copper concentrate with copper grade of 18.72%, copper recovery rate of 89.55%, and zinc content of 2.36%.

[0043] Comparative example 2: This comparative example gives a depressant for the flotation separation of copper-zinc sulfide ore, and the depressant is a water-soluble zinc salt.

[0044] In this comparative example, the water-soluble zinc salt is zinc sulfate.

[0045] This comparative example also gives the application of the depressant for the flotation separation of copper-zinc sulfide ore; the application includes the following steps: Step one, the copper grade of raw ore is 3.06%, the zinc grade is 5.13%, the copper-zinc sulfide ore sample is crushed and ground, the copper-zinc sulfide ore sample is ground to a fineness of-0.074 mm, the copper-zinc sulfide ore sample with a fineness of-0.074 mm accounts for 80wt% of the total copper-zinc sulfide ore sample, then the copper-zinc sulfide ore sample is placed in a flotation tank for slurry preparation, and a copper-zinc sulfide ore slurry with a mass percentage of 35% is obtained; Step two, a pH adjusting agent is added to the copper-zinc sulfide ore slurry in step one, the pH is adjusted to 9.0, stirring for 5 min, then zinc sulfate 200g / t is added, stirring for 3 min, then a roughing collector (butyl xanthate 60g / t) is added, stirring for 2 min, then a foaming agent (No. 2 oil 30g / t) is added, stirring for 2 min, then air flotation is carried out, and the froth is scraped for 5 min, to obtain a roughing copper concentrate and a roughing zinc concentrate; Step three, zinc sulfate 100g / t is added to the roughing copper concentrate in step two, stirring for 3 min, then first cleaning is carried out, then zinc sulfate 50g / t is added to the roughing copper concentrate after first cleaning, stirring for 2 min, then second cleaning is carried out, finally a copper concentrate with a copper grade of 19.51%, a copper recovery rate of 90.79% and a zinc content of 2.12% is obtained.

Claims

1. A combination depressant for the flotation separation of copper-zinc sulphide ores, characterised in that, The combination inhibitor comprises sodium tartrate and zinc sulfate, and the mass ratio of sodium tartrate to zinc sulfate is 1: (0.5-2.5).

2. A combination depressant for the flotation separation of copper-zinc sulphide ores as claimed in claim 1, wherein, The mass ratio of sodium tartrate to zinc sulfate is 1:

1.

3. The combination inhibitor for copper-zinc sulfide ore flotation separation according to claim 1 is applied to copper-zinc sulfide ore flotation separation. The application comprises the following steps: Step one, after crushing and grinding the copper-zinc sulfide ore sample to a certain fineness, slurry is prepared; Step two, a pH regulator is added to the copper-zinc sulfide ore slurry in step one to adjust the pH of the copper-zinc sulfide ore slurry to 6-11, and then the combination inhibitor, the roughing collector and the frother are added in sequence, followed by aeration flotation, scraping for 5 min to obtain the roughing copper concentrate and the roughing zinc concentrate; Step three, the combination inhibitor is added to the roughing copper concentrate in step two for the first cleaning, and the combination inhibitor is added to the roughing copper concentrate after the first cleaning for the second cleaning to obtain the final copper concentrate.

4. The use according to claim 3, wherein the compound is ###0002### In step one, the copper-zinc sulfide ore sample is ground to a fineness of-0.074 mm, and the copper-zinc sulfide ore sample with a fineness of-0.074 mm accounts for 50wt%-90wt% of the copper-zinc sulfide ore sample; In step one, the mass percentage of the copper-zinc sulfide ore slurry is 30wt%-45wt%.

5. The use according to claim 3, wherein the compound is ###0002### In step two, the roughing collector is one or more than one combination of ethyl xanthate, butyl xanthate, butyl ammonium black drug and ethylthiuram. In step two, the frother is one or more than one combination of No. 2 oil, pine oil and methyl isobutyl carbinol.

6. The use according to claim 3, wherein the compound is ###0002### In step two, the amount of sodium tartrate in the combination inhibitor is 100-400g / t, the amount of zinc sulfate in the combination inhibitor is 40-300g / t, the amount of the roughing collector is 10-100g / t, and the amount of the frother is 10-60g / t.

7. The use according to claim 3, wherein the compound is ###00003### or a pharmaceutically acceptable salt thereof. In the first cleaning of step three, the amount of sodium tartrate in the combination inhibitor is 50-200g / t, and the amount of zinc sulfate in the combination inhibitor is 20-150g / t; In the second cleaning of step three, the amount of sodium tartrate in the combination inhibitor is 25-100g / t, and the amount of zinc sulfate in the combination inhibitor is 10-75g / t.