A mycophenolic acid chemiluminescence immunoassay reagent and its preparation and detection method

By combining the principles of competitive assay and chemiluminescence assay with magnetic microparticle technology, a mycophenolic acid chemiluminescent immunoassay reagent suitable for fully automated chemiluminescence immunoassay analyzers was prepared. This solves the problems of speed, accuracy, and automation in the detection of mycophenolic acid content in existing technologies, and achieves high-efficiency detection with low technical requirements.

CN122361803APending Publication Date: 2026-07-10SUZHOU EVERMED BIOMEDICAL CO LTD
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Patent Information

Application Number
CN202412000359.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2026-07-10

AI Technical Summary

Technical Problem

Existing technologies are difficult to detect the content of mycophenolic acid quickly and accurately, and require highly skilled personnel. They also cannot be efficiently coupled with fully automated chemiluminescence immunoassay analyzers.

Method used

Using the competitive method principle, magnetic microparticles are used as the solid phase of the immunoreaction. Combined with chemiluminescence, the concentration of mycophenolic acid is detected by competitive binding between mycophenolic acid-alkaline phosphatase conjugate and anti-mycophenolic acid specific antibody using a fully automated chemiluminescence immunoassay analyzer. A detection reagent containing anti-mycophenolic acid specific antibody and chemiluminescence reagent is prepared.

Benefits of technology

It enables rapid, sensitive, and accurate detection of mycophenolic acid content, is suitable for fully automated chemiluminescence immunoassay analyzers, reduces the technical requirements for testing personnel, and improves testing efficiency and accuracy.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application relates to a kind of mycophenolic acid detection reagent and its preparation and detection method, specifically a kind of mycophenolic acid chemiluminescence immunoassay reagent and its preparation and detection method, comprising: anti mycophenolic acid specific antibody, for detecting the indicating reagent of anti mycophenolic acid specific antibody-mycophenolic acid combination;The above anti mycophenolic acid specific antibody is obtained by mycophenolic acid immunogen immunization animal.The present application has the advantages that: the mycophenolic acid immunogen of the present application is specific, and immunogenicity is high, and the prepared anti mycophenolic acid specific antibody is specific, and titer is high;Chemiluminescence immunoassay reagent containing the above anti mycophenolic acid specific antibody can determine the mycophenolic acid content in sample conveniently, quickly and accurately, and multiple samples can be simultaneously determined on full-automatic chemiluminescence immunoassay analyzer, realize the high-throughput rapid determination of mycophenolic acid, and the accuracy is high, and the specificity is strong, and accuracy and detection efficiency have been greatly improved.
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