Solid-liquid separation device for medical intermediate processing

Abstract

The utility model relates to the technical field of medical intermediate processing, in particular to a solid-liquid separation device for medical intermediate processing. Comprising a separation box, and solves the problems that in the prior art, when solid-liquid separation treatment is carried out on medical intermediates, the medical intermediates are generally filtered through a static screen, but the filtering process is time-consuming and labor-consuming, and the medical intermediates are filtered through a single static screen; generally, only larger medical intermediates can be filtered, but smaller medical intermediates cannot be filtered, so that the filtering effect and efficiency of the medical intermediates after being filtered can be influenced, and in addition, after being used for a long time, the filtering plate can be damaged or blocked and the like, so that the medical intermediates cannot be filtered. At the moment, if the filter plate is not detached, cleaned or replaced, the filtering effect of the filter plate is greatly influenced, and the filtering effect of the medical intermediate after filtering is also influenced.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical intermediate processing, in particular to a solid-liquid separation device for pharmaceutical intermediate processing. Background Art

[0002] Pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product does not require a drug production license and can be produced in ordinary chemical plants. As long as it reaches a certain level, it can be used for drug synthesis. When processing pharmaceutical intermediates, a solid-liquid separation device for pharmaceutical intermediate processing is required.

[0003] At present, when pharmaceutical intermediates are subjected to solid-liquid separation, they are generally filtered through a static screen. Although this method can also filter pharmaceutical intermediates, the filtering process is time-consuming and labor-intensive. When pharmaceutical intermediates are filtered through a single static screen, only larger pharmaceutical intermediates can generally be filtered, while smaller pharmaceutical intermediates will not be filtered, which will affect the filtering effect and efficiency of the pharmaceutical intermediates after filtration. In addition, after long-term use, the filter plate will be damaged or blocked. At this time, if the filter plate is not disassembled, cleaned or replaced, the filtering effect of the filter plate will be greatly affected, which will also affect the filtering effect of the pharmaceutical intermediates after filtration. Utility Model Content

[0004] The purpose of the utility model is to provide a solid-liquid separation device for processing pharmaceutical intermediates, comprising a separation box and also comprising:

[0005] A mixing drum is fixedly connected to the upper surface of the separation box via a fixing frame, and a sealing cover is fixedly connected to the upper side of the mixing drum via bolts;

[0006] A stirring assembly is arranged inside the stirring drum and is used to stir the pharmaceutical intermediate inside the stirring drum;

[0007] The first filter plate and the second filter plate are both located inside the separation box, and the filter holes opened inside the first filter plate have a larger aperture than the filter holes opened inside the second filter plate;

[0008] A driving assembly is symmetrically arranged inside the separation box and is used to make the first filter plate and the second filter plate move up and down synchronously;

[0009] The buffer reset assembly is symmetrically arranged on both sides of the inner wall of the separation box and is used to buffer the movement of the first filter plate and the second filter plate, and can also reset the first filter plate and the second filter plate.

[0010] As a further improvement of the present technical solution, the stirring assembly includes a driving motor fixedly connected to the upper surface of the sealing cover, the output shaft of the driving motor is fixedly connected to a rotating rod through a coupling, the bottom of the rotating rod is fixedly connected to a turntable, the outside of the turntable is fixedly connected to a plurality of stirring plates, the outside of the rotating rod is fixedly connected to a plurality of stirring blades, the bottom of the stirring drum is connected to a drain pipe through a solenoid valve, and the liquid outlet end of the drain pipe is connected to a liquid outlet bucket.

[0011] As a further improvement of the present technical solution, a plurality of snap-in plates are provided inside the separation box, and snap-in grooves for snapping in T-shaped plates are opened inside the plurality of snap-in plates. The plurality of T-shaped plates and the snap-in plates are fixedly connected by bolts, wherein opposite sides of two of the T-shaped plates are respectively fixedly connected to the two sides of the outer wall of the first filter plate, and opposite sides of the other two T-shaped plates are respectively fixedly connected to the two sides of the outer wall of the second filter plate.

[0012] As a further improvement of the present technical solution, the driving assembly includes driving rods symmetrically arranged inside the separation box, the two ends of the two driving rods are respectively rotatably connected to the two sides of the inner wall of the separation box, a reciprocating motor is fixedly connected to one side of the separation box, the output shaft of the reciprocating motor is fixedly connected to one end of one of the driving rods through a coupling, the two driving rods are connected by a belt and a driving wheel transmission, the outside of the two driving rods are symmetrically provided with cams, the upper surfaces of the two clamping plates are symmetrically provided with connecting rods, the top ends of the multiple connecting rods are fixedly connected with resistance disks, the upper surfaces of the multiple resistance disks are provided with movable grooves for the cams to move, and a movable plate is fixedly connected between every two clamping plates.

[0013] As a further improvement of the present technical solution, the buffer reset assembly includes a buffer frame symmetrically arranged on both sides of the inner wall of the separation box, a partition plate is fixedly connected to the interior of the buffer frame, a sliding rod is fixedly connected to the interior of the buffer frame, and the two ends of the sliding rod are respectively fixedly connected to the internal top end and the internal bottom end of the buffer frame, and the outsides of the plurality of the clamping plates are symmetrically provided with extrusion blocks, and the insides of the plurality of the extrusion blocks are provided with guide grooves for the movement of the sliding rod, and the outside of the sliding rod is sleeved with two reset springs, one of the reset springs is in contact with the extrusion block and the partition plate, and the other reset spring is in contact with the extrusion block and the buffer frame.

[0014] As a further improvement of the technical solution, a liquid collection frame is provided at the inner bottom end of the separation box.

[0015] Compared with the prior art, the utility model has the following beneficial effects:

[0016] In the solid-liquid separation device for processing pharmaceutical intermediates, the stirring component, the driving component and the buffer reset component are provided. When the pharmaceutical intermediates need to be subjected to solid-liquid separation, the pharmaceutical intermediates only need to be added into the stirring drum first. At this time, the stirring component starts to operate. The stirring component can effectively stir the pharmaceutical intermediates in the stirring drum, thereby preventing the pharmaceutical intermediates from becoming sticky due to cooling, which affects the effect of solid-liquid separation. After the pharmaceutical intermediates are stirred, they will fall into the separation box. At this time, the driving component starts to operate. The driving component can effectively drive the first filter plate and the second filter plate to move synchronously. During the operation of the driving component, the buffer reset component will also be affected synchronously. At this time, the driving component can cooperate with the buffer reset component to repeatedly move the first filter plate and the second filter plate up and down, thereby filtering the pharmaceutical intermediates on the upper surfaces of the first filter plate and the second filter plate. Since the aperture size inside the first filter plate is larger than the aperture size inside the second filter plate, the pharmaceutical intermediates can be fully filtered by the first filter plate and the second filter plate at this time, thereby achieving the purpose of solid-liquid separation of the pharmaceutical intermediates, saving time and effort. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the three-dimensional structure of the utility model after the sealing cover is opened;

[0019] Figure 3 It is a cutaway three-dimensional structural schematic diagram of the separation box in the utility model;

[0020] Figure 4 This is a schematic diagram of the three-dimensional structure after the first filter plate and the second filter plate in the utility model are disassembled;

[0021] Figure 5 It is a cutaway three-dimensional structural schematic diagram of the buffer frame in the utility model;

[0022] Figure 6 for Figure 3 Schematic diagram of the enlarged structure of the A area in the middle;

[0023] Figure 7 for Figure 4 Schematic diagram of the enlarged structure of the middle B area;

[0024] Figure 8 for Figure 5 Schematic diagram of the enlarged structure of the C area in the middle.

[0025] The meaning of each number in the figure is:

[0026] 1. Separation box; 2. Liquid collection frame; 3. Fixed frame; 4. Mixing drum; 5. Sealing cover; 6. Driving motor; 7. Rotating rod; 8. Turntable; 9. Stirring plate; 10. Stirring blade; 11. Solenoid valve; 12. Drain pipe; 13. Liquid outlet bucket; 14. Reciprocating motor; 15. First filter plate; 16. Second filter plate; 17. Snap-on plate; 18. Buffer frame; 19. Driving rod; 20. Cam; 21. Belt; 22. Contact plate; 23. Connecting rod; 24. T-shaped plate; 25. Partition plate; 26. Slide rod; 27. Extrusion block; 28. Reset spring; 29. ​​Moving plate. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] See also Figure 1 - Figure 8 As shown, this embodiment provides a solid-liquid separation device for processing pharmaceutical intermediates, including a separation box 1, and also including:

[0029] The mixing drum 4 is fixedly connected to the upper surface of the separation box 1 through the fixing frame 3, and a sealing cover 5 is fixedly connected to the upper side of the mixing drum 4 through bolts;

[0030] A stirring assembly is arranged inside the stirring drum 4 and is used to stir the pharmaceutical intermediate inside the stirring drum 4;

[0031] The first filter plate 15 and the second filter plate 16 are both located inside the separation box 1, and the filter holes opened inside the first filter plate 15 have a larger aperture than the filter holes opened inside the second filter plate 16;

[0032] A driving assembly is symmetrically arranged inside the separation box 1 and is used to make the first filter plate 15 and the second filter plate 16 move up and down synchronously;

[0033] The buffer reset assembly is symmetrically arranged on both sides of the inner wall of the separation box 1 and is used to buffer the movement of the first filter plate 15 and the second filter plate 16 and enable the first filter plate 15 and the second filter plate 16 to reset and move.

[0034] The above working principle: when it is necessary to perform solid-liquid separation on the pharmaceutical intermediate, the pharmaceutical intermediate only needs to be added into the mixing drum 4 first, and the stirring component starts to operate at this time. The stirring component can effectively stir the pharmaceutical intermediate inside the mixing drum 4, thereby preventing the pharmaceutical intermediate from becoming viscous when cooled, which affects the effect of solid-liquid separation. After the pharmaceutical intermediate is stirred, it will fall into the separation box 1, and the driving component starts to operate at this time. The driving component can effectively drive the first filter plate 15 and the second filter plate 16 to move synchronously. During the operation of the driving component, the buffer reset component will also be affected synchronously. At this time, the driving component can cooperate with the buffer reset component to make the first filter plate 15 and the second filter plate 16 repeatedly move up and down, so that the pharmaceutical intermediate on the upper surface of the first filter plate 15 and the second filter plate 16 can be filtered. Since the aperture size inside the first filter plate 15 is larger than the aperture size inside the second filter plate 16, the pharmaceutical intermediate can be fully filtered by the first filter plate 15 and the second filter plate 16 at this time, so as to achieve the purpose of solid-liquid separation of the pharmaceutical intermediate, saving time and effort.

[0035] In order to effectively stir the pharmaceutical intermediates in the mixing drum 4, the stirring assembly includes a driving motor 6 fixedly connected to the upper surface of the sealing cover 5, the output shaft of the driving motor 6 is fixedly connected to the rotating rod 7 through a coupling, the bottom of the rotating rod 7 is fixedly connected to a turntable 8, the outside of the turntable 8 is fixedly connected to a plurality of stirring plates 9, the outside of the rotating rod 7 is fixedly connected to a plurality of stirring blades 10, the bottom of the mixing drum 4 is connected to a drain pipe 12 through an electromagnetic valve 11, and the liquid outlet end of the drain pipe 12 is connected to a liquid outlet bucket 13. When the pharmaceutical intermediates need to be stirred, the driving motor 6 is turned on. The rotating rod 7 starts to run, driving the rotating rod 7 to rotate synchronously, the rotating rod 7 then drives the turntable 8 to rotate synchronously, the turntable 8 then drives the stirring plate 9 to rotate synchronously, and the rotating rod 7 also drives the stirring blade 10 to rotate synchronously. At this time, the pharmaceutical intermediate inside the stirring drum 4 can be effectively stirred by the stirring plate 9 and the stirring blade 10, so as to prevent the pharmaceutical intermediate from cooling and becoming viscous. When the pharmaceutical intermediate is stirred, the solenoid valve 11 is opened. At this time, the pharmaceutical intermediate is transmitted to the liquid outlet hopper 13 through the discharge pipe 12, and then discharged into the separation box 1 through the liquid outlet hopper 13.

[0036] Taking into account that the first filter plate 15 and the second filter plate 16 may be clogged or damaged after long-term use, a plurality of snap-in plates 17 are provided inside the separation box 1, and snap-in grooves for snapping in the T-shaped plate 24 are provided inside the plurality of snap-in plates 17. The plurality of T-shaped plates 24 are fixedly connected to the snap-in plates 17 by bolts, wherein the opposite sides of two T-shaped plates 24 are respectively fixedly connected to the two sides of the outer wall of the first filter plate 15, and the opposite sides of the other two T-shaped plates 24 are respectively fixedly connected to the two sides of the outer wall of the second filter plate 16. When it is necessary to disassemble, replace or clean the first filter plate 15 or the second filter plate 16, it is only necessary to unscrew the bolts and then pull the T-shaped plate 24 out of the snap-in groove inside the snap-in plate 17. At this time, the first filter plate 15 or the second filter plate 16 can be disassembled, thereby facilitating the staff to replace or clean the first filter plate 15 or the second filter plate 16.

[0037] In order to effectively drive the first filter plate 15 and the second filter plate 16 to move synchronously, the driving assembly includes a driving rod 19 symmetrically arranged inside the separation box 1, and the two ends of the two driving rods 19 are respectively rotatably connected to the two sides of the inner wall of the separation box 1, and a reciprocating motor 14 is fixedly connected to one side of the separation box 1, and the output shaft of the reciprocating motor 14 is fixedly connected to one end of one of the driving rods 19 through a coupling, and the two driving rods 19 are connected by a belt 21 and a driving wheel transmission connection, and the outsides of the two driving rods 19 are symmetrically provided with cams 20, wherein the upper surfaces of the two clamping plates 17 are symmetrically provided with connecting rods 23, and the tops of the multiple connecting rods 23 are fixedly connected with a contact disk 22, and the upper surfaces of the multiple contact disks 22 are provided with movable grooves for the cam 20 to move, and a moving plate 29 is fixedly connected between every two clamping plates 17. When the pharmaceutical intermediate falls onto the upper surface of the first filter plate 15, the reciprocating motor 14 starts to run, driving one of the driving rods 19 to rotate synchronously. Since the two driving rods 19 are connected by a belt 21 and a driving wheel for transmission, the two driving rods 19 will rotate synchronously at this time, and multiple cams 20 will rotate synchronously with the driving rods 19. During the rotation, the cams 20 will squeeze the contact disk 22 synchronously, and the contact disk 22 will drive the connecting rod 23 to move synchronously. The connecting rod 23 will drive two of the clamping plates 17 to move synchronously, and the two clamping plates 17 will drive the other two clamping plates 17 to move synchronously through the moving plate 29. At this time, the first filter plate 15 and the second filter plate 16 can be moved synchronously, so that the first filter plate 15 and the second filter plate 16 can effectively filter the pharmaceutical intermediates. The sizes of the two driving wheels are inconsistent, so it will not affect the transmission connection relationship between the two driving rods 19.

[0038] In order to enable the first filter plate 15 and the second filter plate 16 to reciprocate and move up and down, the buffer reset assembly includes a buffer frame 18 symmetrically arranged on both sides of the inner wall of the separation box 1, and the interior of the buffer frame 18 is fixedly connected with a partition plate 25, and the interior of the buffer frame 18 is fixedly connected with a slide bar 26, and the two ends of the slide bar 26 are respectively fixedly connected to the internal top and internal bottom of the buffer frame 18, and the outsides of multiple clamping plates 17 are symmetrically provided with extrusion blocks 27, and the interiors of multiple extrusion blocks 27 are provided with guide grooves for the movement of the slide bar 26. The outside of the slide bar 26 is sleeved with two reset springs 28, one of which is in contact with the extrusion block 27 and the partition plate 25, and the other reset spring 28 is in contact with the extrusion block 27 and the buffer frame 18. During the movement of the second filter plate 16, the snap-on plate 17 will be driven to move synchronously, and the snap-on plate 17 will drive the extrusion block 27 to move synchronously outside the slide bar 26. During the downward movement of the extrusion block 27, the reset spring 28 will be squeezed. When the cam 20 is disengaged from the inside of the abutment disk 22, the reset spring 28 will be reset and move, driving the extrusion block 27 to move synchronously, and the extrusion block 27 will drive the snap-on plate 17 to move synchronously, and the snap-on plate 17 will drive the first filter plate 15 and the second filter plate 16 to reset and move synchronously. This cycle can be repeated to repeatedly move the first filter plate 15 and the second filter plate 16 up and down, thereby effectively improving the filtering effect of the first filter plate 15 and the second filter plate 16 on the pharmaceutical intermediates.

[0039] In addition, in order to conveniently collect and process the liquid, a liquid collection frame 2 is provided at the inner bottom end of the separation box 1. After the pharmaceutical intermediate is filtered through the first filter plate 15 and the second filter plate 16, the solid inside the pharmaceutical intermediate will remain on the first filter plate 15 and the second filter plate 16, while the liquid inside the pharmaceutical intermediate will fall into the liquid collection frame 2. At this time, the liquid inside the pharmaceutical intermediate can be conveniently collected and processed, thereby achieving the effect of solid-liquid separation.

[0040] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the utility model and are not used to limit the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection of the utility model is defined by the attached claims and their equivalents.

Claims

1. A solid-liquid separation device for processing pharmaceutical intermediates, comprising a separation box (1), characterized in that: Also includes: A mixing drum (4) is fixedly connected to the upper surface of the separation box (1) via a fixing frame (3), and a sealing cover (5) is fixedly connected to the upper side of the mixing drum (4) via bolts; A stirring assembly is arranged inside the stirring barrel (4) and is used to stir the pharmaceutical intermediate inside the stirring barrel (4); The first filter plate (15) and the second filter plate (16) are both located inside the separation box (1), and the filter holes provided inside the first filter plate (15) have a larger aperture than the filter holes provided inside the second filter plate (16); A driving assembly is symmetrically arranged inside the separation box (1) and is used to synchronously move the first filter plate (15) and the second filter plate (16) up and down; The buffer reset assembly is symmetrically arranged on both sides of the inner wall of the separation box (1) and is used to buffer the movement of the first filter plate (15) and the second filter plate (16), while enabling the first filter plate (15) and the second filter plate (16) to reset and move.

2. A solid-liquid separation device for processing pharmaceutical intermediates according to claim 1, characterized in that: The stirring assembly comprises a driving motor (6) fixedly connected to the upper surface of the sealing cover (5); the output shaft of the driving motor (6) is fixedly connected to a rotating rod (7) via a coupling; the bottom of the rotating rod (7) is fixedly connected to a rotating disk (8); the outside of the rotating disk (8) is fixedly connected to a plurality of stirring plates (9); the outside of the rotating rod (7) is fixedly connected to a plurality of stirring blades (10); the bottom of the stirring drum (4) is connected to a liquid discharge pipe (12) via a solenoid valve (11); the liquid outlet end of the liquid discharge pipe (12) is connected to a liquid outlet bucket (13).

3. A solid-liquid separation device for processing pharmaceutical intermediates according to claim 1, characterized in that: A plurality of snap-in plates (17) are provided inside the separation box (1), and snap-in grooves for snapping in a T-shaped plate (24) are provided inside the plurality of snap-in plates (17). The plurality of T-shaped plates (24) and the snap-in plates (17) are fixedly connected by bolts, wherein opposite sides of two of the T-shaped plates (24) are respectively fixedly connected to the outer walls of the first filter plate (15), and opposite sides of the other two of the T-shaped plates (24) are respectively fixedly connected to the outer walls of the second filter plate (16).

4. A solid-liquid separation device for processing pharmaceutical intermediates according to claim 3, characterized in that: The driving assembly comprises driving rods (19) symmetrically arranged inside the separation box (1), the two ends of the two driving rods (19) are rotatably connected to the two sides of the inner wall of the separation box (1), a reciprocating motor (14) is fixedly connected to one side of the separation box (1), the output shaft of the reciprocating motor (14) is fixedly connected to one end of one of the driving rods (19) through a coupling, the two driving rods (19) are connected to each other through a belt (21) and a driving wheel transmission, the outsides of the two driving rods (19) are symmetrically provided with cams (20), wherein the upper surfaces of the two clamping plates (17) are symmetrically provided with connecting rods (23), the top ends of the plurality of connecting rods (23) are fixedly connected with a contact disk (22), the upper surfaces of the plurality of contact disks (22) are provided with movable grooves for the cam (20) to move, and a movable plate (29) is fixedly connected between each two clamping plates (17).

5. The solid-liquid separation device for processing pharmaceutical intermediates according to claim 3, characterized in that: The buffer reset assembly comprises a buffer frame (18) symmetrically arranged on both sides of the inner wall of the separation box (1), a partition plate (25) is fixedly connected to the inside of the buffer frame (18), a slide bar (26) is fixedly connected to the inside of the buffer frame (18), and the two ends of the slide bar (26) are respectively fixedly connected to the internal top end and the internal bottom end of the buffer frame (18), and the outsides of the plurality of the clamping plates (17) are symmetrically provided with extrusion blocks (27), and the insides of the plurality of the extrusion blocks (27) are provided with guide grooves for the slide bar (26) to move, and the outside of the slide bar (26) is sleeved with two reset springs (28), one of the reset springs (28) is in contact between the extrusion block (27) and the partition plate (25), and the other reset spring (28) is in contact between the extrusion block (27) and the buffer frame (18).

6. The solid-liquid separation device for processing pharmaceutical intermediates according to claim 1, characterized in that: A liquid collecting frame (2) is provided at the inner bottom end of the separation box (1).

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