Constant temperature device for in-vitro application of autologous tissue stem cells
By designing an autologous tissue stem cell ex vivo application of constant temperature devices, the problem of stem cells being damaged and infected before transplantation is solved, the maintenance of a constant temperature environment and the protection of cell activity are achieved, and the survival rate and transplant success rate of stem cells are improved.
Patent Information
- Application Number
- CN202420902052.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-28
- Publication Date
- 2024-12-13
- Estimated Expiration
- 2034-04-28
AI Technical Summary
During tissue transplantation, the extracted autologous tissue stem cells are easily damaged at unprotected natural temperatures, cell activity is reduced, and ischemic tissues are less resistant to infection, and may even die.
A constant temperature device for the in vitro application of autologous tissue stem cells is designed, including a constant temperature box, a refrigerator, a battery, a cold air delivery pipe and a heat dissipation hole. The refrigerator and a battery are installed in the inner bottom wall of the constant temperature box to provide electrical energy, and the air-conditioning conveys the air-conditioning pipe to the isolation. Above the board, the heat dissipation hole takes away the heat generated by the refrigerator to ensure a constant temperature environment.
Effectively maintain a constant temperature environment, protect cell activity, reduce infection risk, and improve stem cell survival and transplant success rate.
Smart Images

Figure CN222165316U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of stem cell preservation, in particular to a thermostatic device for in vitro application of autologous tissue stem cells. Background Art
[0002] At present, many people will seek the help of plastic surgeons for various problems such as cell aging, mutation or local lesions. Most plastic surgeons will treat them with surgery. This method generally extracts the customer's own tissue stem cells for proliferation and culture, and then re-transplants them into the subcutaneous tissue of the affected area to activate the original tissue cells, allowing the tissue cells to continue to differentiate and divide. Through cell appreciation, the aging facial appearance is repaired and the skin is made more lubricated and elastic.
[0003] During tissue transplantation, the extracted tissue stem cells are in an unprotected natural temperature for a considerable period of time. The cells are away from the normal tissue environment temperature, which can easily cause the cells to be damaged and reduce cell activity. In addition, the transplanted tissue is an ischemic tissue. Before blood supply is re-established, the resistance to infection is bound to be reduced, and the cells may even die. Therefore, those skilled in the art have provided a thermostatic device for the ex vivo application of autologous tissue stem cells to solve the problems raised in the above-mentioned background technology. Utility Model Content
[0004] The purpose of the utility model is to provide a thermostatic device for in vitro application of autologous tissue stem cells to solve the problems raised in the above background technology.
[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:
[0006] A thermostatic device for in vitro application of autologous tissue stem cells comprises a thermostatic box, a partition is fixedly mounted on the inner wall of the thermostatic box, a first insulation board is fixedly mounted on the upper surface of the partition, a refrigerator and a battery are fixedly mounted on the inner bottom wall of the thermostatic box, an output end of the refrigerator is fixedly connected to a cold air delivery pipe, the top end of the cold air delivery pipe respectively penetrates the partition and the first insulation board and extends to the top of the first insulation board, and a plurality of heat dissipation holes arranged at equal distances are opened on the left side and the right side of the thermostatic box.
[0007] As a further solution of the utility model: the outer surface of the constant temperature box is hinged with a box cover by a hinge, a handle is fixedly installed on the upper surface of the box cover, a second insulation board is fixedly installed on the inner wall of the box cover, and a temperature sensor is fixedly installed on the bottom surface of the second insulation board.
[0008] As a further solution of the utility model: a temperature display panel and a controller are fixedly installed on the front side of the thermostatic box, and the temperature display panel is electrically connected to the temperature sensor through a wire.
[0009] As a further solution of the utility model: a protection frame is fixedly installed on the front of the thermostatic box, a protection plate is hinged on the upper surface of the protection frame through a hinge, and the controller is located inside the protection frame.
[0010] As a further solution of the utility model: a sealing ring is fixedly installed on the upper surface of the thermostatic box, two buckles are fixedly installed on the front of the thermostatic box, and two handles are fixedly installed on the front of the box cover, and each of the buckles is buckled with the handles.
[0011] As a further solution of the utility model: a third insulation board is fixedly installed on the inner wall of the thermostatic box, a sponge block is fixedly installed on the upper surface of the first insulation board, and two placement grooves are provided on the upper surface of the sponge block.
[0012] As a further solution of the utility model: four support blocks are fixedly installed on the bottom surface of the thermostatic box, and an anti-slip pad is fixedly installed on the bottom surface of each support block.
[0013] Compared with the prior art, the beneficial effects of the utility model are:
[0014] The thermostatic device for in vitro application of autologous tissue stem cells has a refrigerator and a battery installed on the inner bottom wall of a thermostatic box, so that the battery can provide electric energy for the operation of the refrigerator, and a cold air delivery pipe is connected to the output end of the refrigerator, so that the cold air generated by the refrigerator can be continuously delivered to the top of the partition through the cold air delivery pipe, and a plurality of heat dissipation holes arranged at equal distances are opened on the left side and the right side of the thermostatic box, so that the air outside the thermostatic box can enter the bottom of the partition through the heat dissipation holes, so that the heat generated by the operation of the refrigerator can be taken away when the air circulates. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 It is a three-dimensional structural schematic diagram of a front view of a thermostatic device for in vitro application of autologous tissue stem cells;
[0016] Figure 2 A schematic diagram of the three-dimensional structure of a side view of a thermostatic device for in vitro application of autologous tissue stem cells;
[0017] Figure 3 It is a three-dimensional structural schematic diagram of a front cross-sectional view of a thermostatic device for in vitro application of autologous tissue stem cells;
[0018] Figure 4 It is a three-dimensional structural schematic diagram of a front section view of a protective frame in a constant temperature device for in vitro application of autologous tissue stem cells.
[0019] In the figure: 1. handle; 2. box cover; 3. sealing ring; 4. constant temperature box; 5. heat dissipation hole; 6. support block; 7. protection frame; 8. temperature display panel; 9. protection plate; 10. anti-slip mat; 11. temperature sensor; 12. second insulation board; 13. third insulation board; 14. first insulation board; 15. cold air delivery pipe; 16. refrigerator; 17. battery; 18. partition; 19. sponge block; 20. placement slot; 21. controller; 22. handle; 23. buckle. DETAILED DESCRIPTION
[0020] In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present utility model, unless otherwise specified, "multiple" means two or more.
[0021] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.
[0022] See also Figures 1 to 4In an embodiment of the utility model, a thermostatic device for in vitro application of autologous tissue stem cells includes a thermostatic box 4, a partition 18 is fixedly installed on the inner wall of the thermostatic box 4, a first insulation board 14 is fixedly installed on the upper surface of the partition 18, a refrigerator 16 and a battery 17 are fixedly installed on the inner bottom wall of the thermostatic box 4, an output end of the refrigerator 16 is fixedly connected with a cold air delivery pipe 15, the top of the cold air delivery pipe 15 passes through the partition 18 and the first insulation board 14 respectively and extends to the top of the first insulation board 14, a left side surface of the thermostatic box 4 and a right side surface of the thermostatic box 4 are both provided with a plurality of heat dissipation holes 5 arranged at equal distances, the battery 17 is electrically connected to the refrigerator 16 through a wire, the cold air generated by the refrigerator 16 can be transported to the top of the partition 18 through the cold air delivery pipe 15, and the heat generated when the refrigerator 16 is running can be discharged to the outside of the thermostatic box 4 through the heat dissipation holes 5.
[0023] The outer surface of the thermostatic box 4 is hinged with a box cover 2 through a hinge, and a handle 1 is fixedly installed on the upper surface of the box cover 2. A second insulation board 12 is fixedly installed on the inner wall of the box cover 2, and a temperature sensor 11 is fixedly installed on the bottom surface of the second insulation board 12. The staff can move the device by holding the handle 1. The temperature sensor 11 can monitor the temperature inside the thermostatic box 4 in real time. The front of the thermostatic box 4 is respectively fixedly installed with a temperature display panel 8 and a controller 21. The temperature display panel 8 is electrically connected to the temperature sensor 11 through a wire. The staff can grasp the temperature inside the thermostatic box 4 through the temperature display panel 8, and the staff can conveniently open or close the refrigerator 16 through the controller 21. A protective frame 7 is fixedly installed on the front of the thermostatic box 4, and a protective plate 9 is hinged on the upper surface of the protective frame 7 through a hinge. The controller 21 is located inside the protective frame 7, and the protective frame 7 and the protective plate 9 can protect the controller 21.
[0024] The upper surface of the thermostatic box 4 is fixedly installed with a sealing ring 3, the front of the thermostatic box 4 is fixedly installed with two buckles 23, and the front of the box cover 2 is fixedly installed with two handles 22, each buckle 23 is buckled with the handle 22, and the box cover 2 can squeeze the sealing ring 3 by buckling the two buckles 23 with the two handles 22, so that the cold air inside the thermostatic box 4 can be prevented from overflowing, and the inner wall of the thermostatic box 4 is fixedly installed with a third insulation board 13, and the upper surface of the first insulation board 14 is fixedly installed with a sponge block 19, and the sponge block 19 Two placement grooves 20 are provided on the upper surface of the sponge block 19. The first insulation board 14, the second insulation board 12 and the third insulation board 13 can prevent the rapid loss of cold air. By providing two placement grooves 20 on the upper surface of the sponge block 19, the container containing autologous tissue stem cells can be stably placed inside the constant temperature box 4. Four support blocks 6 are fixedly installed on the bottom surface of the constant temperature box 4. The bottom surface of each support block 6 is fixedly installed with an anti-skid pad 10. The anti-skid pad 10 can increase the friction between the contact surface, so that the device can be stably placed.
[0025] The working principle of the utility model is: first, the staff starts the refrigerator 16 through the controller 21 and sets a certain temperature. After the refrigerator 16 is started, the cold air generated is continuously transmitted to the top of the partition 18 through the cold air delivery pipe 15, and the air outside the thermostatic box 4 enters the bottom of the partition 18 through the heat dissipation hole 5, and the heat generated by the operation of the refrigerator 16 is discharged to the outside of the thermostatic box 4 through the heat dissipation hole 5. The temperature sensor 11 monitors the temperature inside the thermostatic box 4 in real time and transmits the temperature value to the temperature display panel 8 in real time through the wire.
[0026] The above is only a preferred specific implementation of the utility model, but the protection scope of the utility model is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solution and utility model concept of the utility model within the technical scope disclosed by the utility model, which should be included in the protection scope of the utility model. For those skilled in the art, it is obvious that the utility model is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or basic features of the utility model. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the utility model is limited by the attached claims rather than the above description, so it is intended to include all changes that fall within the meaning and scope of the equivalent elements of the claims in the utility model. Any figure mark in the claims should not be regarded as limiting the claims involved.
[0027] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.
Claims
1. A thermostatic device for in vitro application of autologous tissue stem cells, comprising a thermostatic box (4), It is characterized in that A partition (18) is fixedly mounted on the inner wall of the thermostatic box (4), a first heat-insulating plate (14) is fixedly mounted on the upper surface of the partition (18), a refrigerator (16) and a storage battery (17) are fixedly mounted on the inner bottom wall of the thermostatic box (4), an output end of the refrigerator (16) is fixedly connected to a cold air delivery pipe (15), the top end of the cold air delivery pipe (15) passes through the partition (18) and the first heat-insulating plate (14) and extends to the top of the first heat-insulating plate (14), and a plurality of heat dissipation holes (5) arranged at equal distances are provided on the left side surface and the right side surface of the thermostatic box (4).
2. A thermostatic device for in vitro application of autologous tissue stem cells according to claim 1, It is characterized in that The outer surface of the thermostatic box (4) is hingedly connected to a box cover (2) via a hinge, a handle (1) is fixedly mounted on the upper surface of the box cover (2), a second thermal insulation board (12) is fixedly mounted on the inner wall of the box cover (2), and a temperature sensor (11) is fixedly mounted on the bottom surface of the second thermal insulation board (12).
3. A thermostatic device for in vitro application of autologous tissue stem cells according to claim 1, It is characterized in that A temperature display panel (8) and a controller (21) are fixedly mounted on the front of the thermostatic box (4), respectively; the temperature display panel (8) is electrically connected to the temperature sensor (11) via a wire.
4. A thermostatic device for in vitro application of autologous tissue stem cells according to claim 3, It is characterized in that A protective frame (7) is fixedly mounted on the front of the thermostatic box (4); a protective plate (9) is hingedly connected to the upper surface of the protective frame (7) via a hinge; and the controller (21) is located inside the protective frame (7).
5. The thermostatic device for in vitro application of autologous tissue stem cells according to claim 2, It is characterized in that A sealing ring (3) is fixedly mounted on the upper surface of the thermostatic box (4), two buckles (23) are fixedly mounted on the front surface of the thermostatic box (4), and two handles (22) are fixedly mounted on the front surface of the box cover (2), and each of the buckles (23) is buckled with a handle (22).
6. The thermostatic device for in vitro application of autologous tissue stem cells according to claim 1, It is characterized in that A third heat-insulating plate (13) is fixedly mounted on the inner wall of the thermostatic box (4), a sponge block (19) is fixedly mounted on the upper surface of the first heat-insulating plate (14), and two placement grooves (20) are provided on the upper surface of the sponge block (19).
7. The thermostatic device for in vitro application of autologous tissue stem cells according to claim 1, It is characterized in that Four support blocks (6) are fixedly mounted on the bottom surface of the thermostatic box (4), and an anti-slip pad (10) is fixedly mounted on the bottom surface of each support block (6).
