Novel efficient mouse intraperitoneal injection fixator
By designing a new type of mouse intraperitoneal injection fixator, the mice are stably fixed by using fixing plates, limiting plates and suction cups, the problems of biting and cumbersome operation in the prior art are solved, and efficient and safe intraperitoneal injection operation is achieved.
Patent Information
- Application Number
- CN202420402155.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-01
- Publication Date
- 2025-03-11
- Estimated Expiration
- 2034-03-01
AI Technical Summary
The existing intraperitoneal injection fixators of mice are at risk of being bitten during the fixation process, and the operation steps are cumbersome, which affects the experimental efficiency and cannot adapt to mice of different volumes.
A new high-efficiency mouse intraperitoneal injection fixator was designed, and the mice were squeezed and fixed through the fixing plate, left and right limit plate and mobile plate. The fixing plate and limit plate were adjusted to accommodate mice of different volumes, and the tail of the mice was fixed through suction cups to reduce the risk of bite.
The stable fixation of mice was achieved, the risk of bite was reduced, the operation steps were simplified, the experimental efficiency was improved, and the ability to adapt to mice of different volumes was adapted.
Smart Images
Figure CN222584712U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of experimental instruments, in particular to a novel and efficient mouse abdominal cavity injection fixer. Background Art
[0002] At present, in the field of biology and basic medicine, there are more and more operations related to intraperitoneal injection of mice. During the manual fixation operation, since one-hand fixation is required, there is a great risk of being bitten by mice during the process of catching mice and performing injection operations. The existing closed fixators are mainly divided into two types:
[0003] The first type: It is mainly used for tail vein injection in mice. Therefore, intraperitoneal injection can only be performed through the small holes on both sides. It is impossible to perform injection from the front of the mouse's abdominal cavity. In addition, the mouse cannot be better fixed during the operation, which affects the experimental effect.
[0004] The second type can be used for both tail vein and intraperitoneal injections in mice. However, during the fixation process, the mouse's limbs need to be manually extended from the holes of the fixator when the mouse is awake and forcibly fixed with rubber bands. There is still a great risk of being bitten during the fixation process. At the same time, the cumbersome operating steps greatly affect the experimental efficiency. At the same time, the instrument is suitable for a small size range of mice and cannot be adjusted.
[0005] Therefore, a new and efficient mouse intraperitoneal injection fixator is proposed to solve the above technical problems. Utility Model Content
[0006] The utility model provides a novel and efficient mouse peritoneal injection fixer, which solves the above technical problems.
[0007] In order to solve the above technical problems, the utility model provides a novel and efficient mouse intraperitoneal injection fixer, comprising a base plate, a fixing plate being fixed on the upper end of the base plate, a left slide groove and a right slide groove being arranged on the side of the fixing plate, a connecting column and a connecting rod being slidably connected inside the left slide groove and the right slide groove respectively, a left limiting plate or a right limiting plate being fixed on one end of the connecting column and the connecting rod respectively, a rotating circle and a rotating circle being connected on the surfaces of the connecting column and the connecting rod respectively through threaded rotation, a movable rail being fixed on the upper end of the fixing plate, a locking plate being slidably connected inside the movable rail, a screw being rotatably connected on the surface of the locking plate through threaded rotation, the movable plate being fixedly connected on the lower end of the screw, and an injection port being arranged at the bottom of the base plate.
[0008] Preferably, a side plate is fixed to the upper end of the bottom plate, and fixed suction cups are provided at the upper ends of the side plates and the bottom of the bottom plate, and the position of the right suction cup of the side plate is higher than that of the left suction cup.
[0009] Preferably, the fixing plate, the side plate and the bottom plate are made of transparent resin material.
[0010] Compared with the related art, the novel and efficient mouse intraperitoneal injection fixator provided by the utility model has the following advantages:
[0011] Beneficial effects:
[0012] The utility model squeezes the mouse by the fixed plate, the limiting plates on the left and right sides and the movable plate, limits the activity space of the mouse, thereby ensuring the smooth progress of the injection, and can be adjusted according to the different sizes of the mice, thereby fixing mice of different sizes. The whole process only requires grabbing the tail of the mouse and putting it in the middle of the fixed plate, thereby reducing the risk of being bitten. The position of the mouse can be adjusted and fixed by adjusting the fixed plate, the limiting plates on the left and right sides and the movable plate, so that the mouse can keep its abdomen upward and its head slightly tilted downward, with its abdomen slightly lifted by the movable plate, thereby helping the experimenter to complete the intraperitoneal injection operation more easily and accurately. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is the main structure diagram of the utility model;
[0014] Figure 2 It is a cutaway structural diagram of the utility model;
[0015] Figure 3 It is a structural diagram of the left and middle limiting plates of the present invention.
[0016] Numbers in the figure: 1. Side plate; 2. Bottom plate; 3. Left limit plate; 4. Fixed plate; 5. Rotating circle; 6. Right slide groove; 7. Moving rail; 8. Locking plate; 9. Moving plate; 10. Connecting rod; 11. Screw rod; 12. Injection port; 13. Right limit plate; 14. Left slide groove; 15. Connecting column; 16. Rotating circle. DETAILED DESCRIPTION
[0017] Example, by Figure 1-3The utility model includes a novel and efficient mouse intraperitoneal injection fixer, including a base plate 2, a fixing plate 4 is fixed on the upper end of the base plate 2, a left slide groove 14 and a right slide groove 6 are arranged on the side of the fixing plate 4, a connecting column 15 and a connecting rod 10 are slidably connected inside the left slide groove 14 and the right slide groove 6 respectively, a left limiting plate 3 or a right limiting plate 13 are fixed on one end of the connecting column 15 and the connecting rod 10 respectively, a rotating circle 16 and a rotating circle 5 are rotatably connected on the surfaces of the connecting column 15 and the connecting rod 10 respectively through threaded rotation, a moving rail 7 is fixed on the upper end of the fixing plate 4, a locking plate 8 is slidably connected inside the moving rail 7, a screw 11 is rotatably connected on the surface of the locking plate 8 through threaded rotation, a moving plate 9 is fixedly connected on the lower end of the screw 11, an injection port 12 is arranged on the bottom of the base plate 2, a side plate 1 is fixed on the upper end of the base plate 2, a fixed suction cup is arranged on the upper end of the side plate 1 and the bottom of the base plate 2, and the position of the right suction cup of the side plate 1 is higher than that of the left suction cup.
[0018] Grab the mouse's tail and drag it into the fixed plate 4 from the left, first install the right limit plate 13 along the right slide groove 6, adjust the right limit plate 13, rotate the rotating circle 5 on the surface of the right limit plate 13, fix the right limit plate 13, install the locking plate 8 and the moving plate 9 from the left along the movable rail 7, and move it to just above the injection port 12, push the connecting column 15 on the surface of the left limit plate 3 into the left slide groove 14, move the left limit plate 3 to a suitable position, rotate the rotating circle 16 to fix the position of the left limit plate 3, rotate the locking plate 8, and the locking plate 8 drives the moving plate 9 to move downward through the surface thread and the screw 11, then the moving plate 9 squeezes the mouse and finally fixes it inside the fixed plate 4, flip the injection fixture so that the four suction cups on the side plate 1 are at the bottom, and the injection port 12 is facing upward, and the mouse can be intraperitoneally injected through the injection port 12.
Claims
1. A novel and efficient mouse intraperitoneal injection fixer, comprising a bottom plate (2), characterized in that: A fixed plate (4) is fixed to the upper end of the base plate (2), and a left slide groove (14) and a right slide groove (6) are arranged on the side of the fixed plate (4), and a connecting column (15) and a connecting rod (10) are slidably connected inside the left slide groove (14) and the right slide groove (6), respectively, and one end of the connecting column (15) and the connecting rod (10) is fixed with a left limit plate (3) or a right limit plate (13), and the surfaces of the connecting column (15) and the connecting rod (10) are respectively connected with a rotating circle (16) and a rotating circle (5) by threaded rotation, and a movable rail (7) is fixed to the upper end of the fixed plate (4), and a locking plate (8) is slidably connected inside the movable rail (7), and a screw rod (11) is rotatably connected on the surface of the locking plate (8), and a movable plate (9) is fixedly connected to the lower end of the screw rod (11), and an injection port (12) is arranged at the bottom of the base plate (2).
2. A novel and efficient mouse intraperitoneal injection fixator according to claim 1, characterized in that: The upper end of the bottom plate (2) is fixed with a side plate (1), the upper end of the side plate (1) and the bottom of the bottom plate (2) are provided with fixed suction cups, and the position of the right suction cup of the side plate (1) is higher than that of the left suction cup.
3. A novel and efficient mouse intraperitoneal injection fixator according to claim 1, characterized in that: The fixing plate (4), the side plate (1) and the bottom plate (2) are made of transparent resin material.