Distribution station for producing fusidic acid by using fermentation method
By using smooth, dead-angle-free transfer pipes and integrated exhaust valves in the distribution station for the fermentation production of fusidic acid, combined with steam disinfection and sewage treatment systems, the problems of material residue and microbial growth caused by dead corners in the fermentation tank distribution station are solved, thereby improving the flexibility of fermentation production and product quality.
Patent Information
- Application Number
- CN202423146490.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-19
- Publication Date
- 2025-10-17
- Estimated Expiration
- 2034-12-19
AI Technical Summary
There are dead corners in the pipes and valves of the fermentation tank distribution station, which leads to material residue and microbial growth, affecting the fermentation quality and safety, and making cleaning difficult.
A distribution station including steam pipes, distribution mains, sewage pipes and branches is designed. It uses smooth, dead-angle-free transplanting pipes and integrated exhaust valves, combined with steam disinfection and sewage systems to ensure the cleaning and disinfection effects of the pipes.
It improves the flexibility and efficiency of fermentation production, reduces the risk of material residue and microbial contamination, and ensures the quality and safety of fermentation products.
Smart Images
Figure CN223448148U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to fermentation engineering technical field especially relates to a distribution station for producing fusidic acid by fermentation method. BACKGROUND
[0002] In the production process of fusidic acid, multiple process steps and multiple raw materials are involved. In order to ensure the smooth progress of each process link and the accurate supply of raw materials, an efficient distribution station is needed to coordinate and manage the flow of materials. For example, in the fermentation process, raw materials such as glucose, soybean powder and corn syrup need to be accurately distributed to the fermentation tank to ensure the smooth progress of fermentation. In the subsequent extraction, purification and other steps, solvents such as butyl acetate, sulfuric acid and methanol also need to be reasonably distributed and controlled through the distribution station. The distribution station can realize accurate metering, conveying and distribution of materials, improve production efficiency and product quality, and at the same time ensure the safety and stability of the production process.
[0003] The current fermentation tank distribution station has dead angles in the use process of its pipeline, valve and other components. On the one hand, the inside of the pipeline may have rough areas due to unreasonable design or improper material selection, causing the material to be easily left over during the flow process. Some valves have screw ports and other parts in their structure, which are easy to hide dirt and difficult to clean thoroughly. First, the material residues will affect the purity and quality of fermentation. The residual material may deteriorate and mix into the subsequent fermentation process, causing the product quality to decline, and even harmful substances may be produced. Second, the dead angle is easy to breed bacteria and microorganisms. In the fermentation environment, once bacteria breed, they will spread rapidly, polluting the entire fermentation system and affecting the success rate of fermentation and the safety of the product. Therefore, in view of the above phenomenon, a distribution station for producing fusidic acid by fermentation method is proposed to meet the needs of actual use. SUMMARY
[0004] The utility model provides a distribution station for producing fusidic acid by fermentation method, solve the current fermentation tank distribution station's pipeline valve etc.
[0005] To solve the above technical problem, the utility model provides a distribution station for producing fusidic acid by fermentation method, including the steam pipeline connected with steam source, the distribution main pipe for supplying steam and the blowdown pipeline connected with wastewater treatment system, the steam pipeline is connected with the input end of distribution main pipe, the blowdown pipeline is connected with the output end of distribution main pipe, be equipped with a plurality of branch pipes on the distribution main pipe, the branch pipe is installed with the inoculation valve, the branch pipe is connected with the inoculation pipeline through the inoculation valve.
[0006] In some embodiments, the inoculum valve comprises a flow control valve and two exhaust valves, which are integrally formed with the cavity of the flow control valve.
[0007] In some embodiments, a steam valve is arranged on the pipeline connecting the steam pipeline and the distribution main pipe.
[0008] In some embodiments, a steam pressure reducing valve is arranged on the pipeline connecting the steam valve and the distribution main pipe.
[0009] In some embodiments, a blowdown valve is arranged on the pipeline connecting the distribution main pipe and the blowdown pipeline.
[0010] In some embodiments, a support rod is arranged below the distribution main pipe, and the distribution main pipe is fixed to the ground through the support rod.
[0011] In some embodiments, the inner wall of the inoculum pipeline is smooth and free of dead angles.
[0012] Compared with the related art, the distribution station for producing fusidic acid by fermentation method has the following beneficial effects:
[0013] The distribution station for producing fusidic acid by fermentation method provided by the utility model connects the exhaust valve and the flow control valve integrally, and the inner wall of the inoculum pipeline is smooth and free of dead angles. In the fermentation environment, the dead angles are easy to hide dirt and accumulate microorganisms. The integrated design of the inoculum valve and the smooth and dead angle-free internal design of the inoculum pipeline make the entire connection part smoother and more continuous, and there is no gap, depression or other place easy to retain impurities, which is convenient for cleaning and disinfection, ensures the sanitary condition of the environment where the gas and materials are located during the exhaust and inoculum processes, and reduces the risk of adversely affecting the quality of the fermentation product.
[0014] The distribution station for producing fusidic acid by fermentation method provided by the utility model has two exhaust valves, so that there are two channels for gas exhaust. During operation, the workers can observe the exhaust state of the two exhaust ports (indirectly judge the internal condition of the pipeline) so as to timely find problems and take corresponding measures for treatment. BRIEF DESCRIPTION OF DRAWINGS
[0015] Figure 1 It is a whole schematic diagram of the utility model;
[0016] Figure 2 It is a small distribution station diagram of the utility model;
[0017] Figure 3 It is a whole structure schematic diagram of the utility model;
[0018] Figure 4 It is a small distribution station structure schematic diagram of the utility model;
[0019] Figure 5 This is a schematic diagram of the structure of the transplanting valve of the present utility model.
[0020] Numbers in the figure: 1, steam pipe; 2, steam valve; 3, steam pressure reducing valve; 4, distribution main; 5, transplanting valve; 51, flow control valve; 52, exhaust valve; 6, transplanting pipe; 7, sewage valve; 8, sewage pipe; 9, support rod. DETAILED DESCRIPTION
[0021] Example 1
[0022] This embodiment provides a dispensing station for producing fusidic acid using a fermentation method, such as Figures 1-2 As shown, the utility model includes a steam pipe 1 connected to a steam source, a distribution main pipe 4 for supplying steam, and a sewage pipe 8 connected to a wastewater treatment system. The steam pipe 1 is connected to the input end of the distribution main pipe 4, and the sewage pipe 8 is connected to the output end of the distribution main pipe 4. The distribution main pipe 4 is provided with a plurality of branch pipes, and the branch pipes are installed with transfer valves 5. The branch pipes are connected to the transfer pipe 6 through the transfer valve 5.
[0023] In this embodiment, during fermentation production, different fermentation tanks may be in different stages of fermentation, some may have just started inoculation, and some may have reached the late stage of fermentation. Multi-channel pipelines can connect these tanks. According to the principle of communicating vessels, as long as the pipelines are unobstructed and the valves are properly controlled, materials, gases, etc. can be transmitted to each other between different tanks. For example, high-quality strains that have completed fermentation can be transplanted from one tank to another tank that has just started fermentation, or when it is necessary to adjust the pressure and composition in the tank, gas can be communicated, which greatly improves the flexibility and ease of operation of fermentation production, reduces tedious operations such as manual handling and transfer, and improves the overall fermentation production efficiency.
[0024] In the fermentation tank dispensing station, steam is introduced primarily for disinfection and sterilization. Steam's high temperature and humidity effectively kill any microorganisms that may be present within pipes, valves, and other related equipment. According to the principle of thermal sterilization, high temperatures can destroy the structure of microbial macromolecules, such as proteins and nucleic acids, rendering them inactive. Generally speaking, when steam temperature reaches approximately 121°C and is maintained for a sufficient period (e.g., 15-30 minutes), it kills most bacteria, spores, and other microorganisms, thereby ensuring that the fermentation process is free of contamination by other bacteria.
[0025] In some fermentation processes, steam can also be used to preheat piping systems and materials. For example, in temperature-sensitive fermentation processes, materials must be preheated to an appropriate temperature before entering the fermenter to ensure a smooth start. Preheating the pipes also reduces heat loss during material transport, helping to maintain a stable temperature throughout the fermentation system.
[0026] When steam flows through pipes and equipment, it gradually cools down due to heat transfer, forming condensed water. If this condensed water is not discharged in time, it will accumulate at the bottom of the pipe. On the one hand, it may affect the circulation of steam and reduce the disinfection and sterilization effect; on the other hand, during the fermentation process, the condensed water may dilute the material or provide conditions for the growth of microorganisms. The sewage pipe 8 can discharge this condensed water by gravity or pressure difference. In terms of pipeline design, the sewage pipe 8 is located at the lowest point of the pipeline system, and gravity is used to allow the condensed water to flow naturally into the sewage pipe 8.
[0027] After disinfection and sterilization or during routine maintenance, the pipes and equipment need to be cleaned, and the impurities generated during the cleaning process (such as residual detergent, microbial corpses, dirt, etc.) will be discharged through the sewage system. In addition, if there are some abnormal conditions during the fermentation process that cause material leakage or other impurities, they can also be discharged through the sewage pipe 8 to keep the pipeline system clean and operating normally. The outlet of the sewage pipe 8 is usually connected to a dedicated wastewater treatment system to ensure that the discharged pollutants are properly treated and will not pollute the environment.
[0028] Example 2
[0029] Based on the first embodiment, Figure 5 As shown, the transplanting valve 5 of this embodiment includes a flow control valve 51 and an exhaust valve 52 . There are two exhaust valves 52 , and both exhaust valves 52 are formed integrally with the cavity of the flow control valve 51 .
[0030] In this embodiment, the exhaust valve 52 is integrated with the flow control valve 51, eliminating screw-type structures that easily create dead corners. This is done for the sake of cleanliness and contamination prevention. In a fermentation environment, dead corners can easily harbor dirt and microorganisms, which can easily accumulate and multiply. The integrated design makes the entire connection smoother and more continuous, eliminating gaps, depressions, and other areas where impurities can easily accumulate. This facilitates cleaning and disinfection, ensures the hygienic conditions of the gas and material environment during exhaust and transfer, and reduces the risk of adverse effects on the quality of the fermented product.
[0031] The design of the two exhaust valves 52 allows two channels for gas exhaust. During operation, the staff can indirectly determine the internal situation of the pipeline by observing the exhaust state of the two exhaust ports (such as the exhaust speed, the state of the gas, etc.). If there is a dead angle in a certain part, the gas may not flow smoothly in that area, which will affect the exhaust performance of the corresponding exhaust port, for example, the exhaust volume becomes smaller or appears intermittently. Based on the principle of uniform gas flow in the pipeline (under normal circumstances, the gas should flow relatively smoothly and uniformly through the pipeline), by comparing the differences in the exhaust conditions of the two exhaust ports, it can be inferred whether there is a dead angle area that hinders the flow of gas in the pipeline, so as to discover problems in time and take appropriate measures to deal with them.
[0032] Example Three
[0033] Based on Example One, as shown in FIG. 3, a steam valve 2 is arranged on the connecting pipeline between the steam pipeline 1 and the distribution main pipe 4 in this embodiment. Figure 1
[0034] In this embodiment, the steam valve 2 serves as the first control checkpoint of the entire steam passage, and its main purpose is to control whether the steam enters the distribution main pipe 4. In the daily operation of the fermenter distribution station, steam supply is not always needed. When the fermenter is in the normal fermentation stage and does not need steam sterilization or preheating, closing the steam valve 2 can prevent steam from entering and avoid wasting energy and unnecessary interference to the fermentation process.
[0035] Example Four
[0036] Based on Example Three, as shown in FIG. 4, a steam pressure reducing valve 3 is arranged on the connecting pipeline between the steam valve 2 and the distribution main pipe 4 in this embodiment. Figure 1
[0037] In this embodiment, different operation links in the fermenter distribution station have different requirements for steam pressure. For example, when steam is used for sterilization, it needs to reach a certain high temperature and high pressure condition to effectively kill microorganisms; while preheating materials or pipelines, a relatively low and stable steam pressure may be needed. The steam pressure reducing valve 3 can reduce the high pressure steam at the inlet to the required pressure value and keep the outlet pressure stable. This is achieved through the pressure sensing and adjusting mechanism inside, such as adjusting the valve opening degree through the cooperation of the valve core and the valve seat or the pilot structure, to adapt to different pressure requirements. In addition, stable steam pressure helps to ensure the quality and uniformity of steam flow.
[0038] Example Five
[0039] Based on Example One, as shown in FIG. 5, a blowdown valve 7 is arranged on the connecting pipeline between the distribution main pipe 4 and the blowdown pipeline 8 in this embodiment. Figure 1
[0040] In this embodiment, drain valve 7 is primarily used to control the opening and closing of drain pipe 8, thereby determining whether condensed water, impurities, and cleaning wastewater are discharged from main distribution pipe 4. During normal operation of the fermenter distribution station, drain valve 7 is opened as needed to perform drainage operations. For example, after steam sterilization, a large amount of condensed water is generated in the pipe. Opening drain valve 7 can promptly drain this condensed water, preventing its accumulation in the pipe and affecting system performance.
[0041] Example 6
[0042] Based on the first embodiment, Figures 3-4 As shown, a support rod 9 is provided below the distribution main pipe 4 of this embodiment, and the distribution main pipe 4 is fixed to the ground through the support rod 9.
[0043] In this embodiment, the distribution main pipe 4, the core component of the entire distribution station, is used to distribute steam and connect various branch pipes. Therefore, it possesses a considerable weight. The primary function of the support rod 9 is to bear the weight of the distribution main pipe 4, firmly anchoring it to the ground and preventing it from sagging or deforming due to its own weight. This is crucial for maintaining the tightness of the distribution main pipe 4 connections, the proper functioning of the valves, and the structural stability of the entire distribution station.
[0044] Example 7
[0045] On the basis of the first embodiment, the inner wall of the transplanting pipe 6 of this embodiment is smooth without dead angles.
[0046] In this embodiment, a new pressure-resistant, high-temperature material is used to make the seed transfer pipe 6. During the fermentation production process, the seed transfer operation often involves different environmental conditions, such as high temperature environments (for example, some microbial fermentations require specific high temperature conditions to ensure the fermentation effect) and certain pressure changes (such as material transportation, pressure differences between the inside and outside of the tank, etc.). The use of the new pressure-resistant, high-temperature material to make the seed transfer pipe 6 is to ensure that the pipe can maintain its structural integrity under these complex and relatively extreme conditions, and will not deform or damage due to inability to withstand high temperatures, nor will it rupture due to pressure, thereby ensuring that the seed transfer operation can continue stably and safely.
[0047] For fermentation, the purity of the material is crucial. Any residual liquid may breed bacteria or affect the quality of subsequent fermentation batches. The smooth, corner-free interior design allows the material to flow smoothly through the pipe without accumulating or stagnating in corners or depressions. Based on the principles of fluid mechanics, the smooth inner wall can reduce the resistance to material flow, allowing the material to be transported more efficiently in the pipe. It also prevents residual liquid from breeding microorganisms and contaminating the fermentation process, helping to maintain the cleanliness and stability of the entire fermentation process.
[0048] Working principle: the exhaust valve 52 and the flow control valve 51 are integrally connected, the inner wall of the pipeline 6 is smooth and has no dead angle, in the fermentation environment, the dead angle is easy to hide dirt, and the microorganisms are easy to accumulate and reproduce, the integrated design of the transfer valve 5 and the smooth inner design of the transfer pipeline 6 make the whole connection part more smooth and continuous, there is no gap, depression and other places that are easy to retain impurities, which is convenient for cleaning and disinfection, ensures the sanitary condition of the environment of gas and material during the exhaust and transfer process, and reduces the risk of affecting the quality of the fermentation product. The design of the two exhaust valves 52 makes the gas exhaust have two channels, during operation, the staff can indirectly judge the internal situation of the pipeline by observing the exhaust state of the two exhaust ports (such as the exhaust speed, the state of the gas, etc.), so as to find out the problem in time and take corresponding measures to deal with it.
Claims
1. A dispensing station for producing fusidic acid using a fermentation method, characterized in that: It includes a steam pipe connected to a steam source, a distribution main pipe for supplying steam, and a sewage pipe connected to a wastewater treatment system. The steam pipe is connected to the input end of the distribution main pipe, and the sewage pipe is connected to the output end of the distribution main pipe. The distribution main pipe is provided with several branch pipes, each of which is equipped with a transplant valve, and the branch pipe is connected to the transplant pipe through the transplant valve.
2. A dispensing station for producing fusidic acid using a fermentation method according to claim 1, characterized in that: The transplanting valve includes a flow control valve and an exhaust valve. There are two exhaust valves, and both exhaust valves are formed integrally with the cavity of the flow control valve.
3. A dispensing station for producing fusidic acid using a fermentation method according to claim 1, characterized in that: A steam valve is provided on the pipeline connecting the steam pipeline and the distribution main pipe.
4. A dispensing station for producing fusidic acid using a fermentation method according to claim 3, characterized in that: A steam pressure reducing valve is provided on the connecting pipeline between the steam valve and the distribution main pipe.
5. A dispensing station for producing fusidic acid using a fermentation method according to claim 1, characterized in that: A sewage valve is provided on the connecting pipeline between the distribution main pipe and the sewage pipe.
6. A dispensing station for producing fusidic acid using a fermentation method according to claim 1, characterized in that: A support rod is provided below the distribution main pipe, and the distribution main pipe is fixed to the ground through the support rod.
7. A dispensing station for producing fusidic acid using a fermentation method according to claim 1, characterized in that: The inner wall of the transplanting pipeline is smooth and has no dead angles.