Immunohistochemical dyeing machine heating structure with leakage prevention function and slide heating device of immunohistochemical dyeing machine heating structure
By setting slots and drainage holes between the heating block and the guide block, the problem of reagent leakage is solved, the heating membrane is protected, and the heating efficiency and service life of the immunohistochemical staining equipment are improved.
Patent Information
- Application Number
- CN202520900430.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-08
- Publication Date
- 2026-05-15
- Estimated Expiration
- 2035-05-08
AI Technical Summary
The design of the heating element in existing immunohistochemistry staining machines has an unreasonable drain port, which leads to reagent leakage, corrosion of the heating film, reduced heating efficiency, and increased equipment failure rate.
Top and bottom slots and drainage holes are provided between the heating block and the guide block. The guide block is equipped with a guide plate and a limiting part to prevent reagents from leaking into the heating membrane. The overflowing liquid is collected through the guide plate and the collection tank.
It effectively prevents reagent leakage, protects the heating film, improves heat transfer efficiency, reduces equipment failure rate, and extends equipment life.
Smart Images
Figure CN224249852U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of slide specimen processing equipment, and in particular to a heating structure for an immunohistochemical staining machine with anti-leakage. Background Technology
[0002] Immunohistochemical staining is a commonly used experimental technique in biomedical research and clinical diagnosis. During the staining process, the heating plate plays a crucial role in maintaining sample temperature and promoting reagent penetration and reaction. Its performance directly affects the staining effect and experimental efficiency. However, existing heating plate designs often suffer from poorly designed drain ports. When reagents are discharged or overflow, they can easily flow from the drain port directly to the area below the heating plate, causing the reagents to directly contact and corrode the heating film. This not only reduces heating efficiency but may also cause the heating film to peel off from the aluminum block, increasing equipment failure rate and maintenance costs. Utility Model Content
[0003] The purpose of this invention is to overcome the shortcomings of the prior art and provide a leak-proof heating structure for an immunohistochemical staining machine, so as to solve the technical problem that the existing slide heating mechanism is prone to equipment failure due to reagent leakage.
[0004] To achieve the above objectives, the present invention adopts the following technical solution:
[0005] An embodiment of this utility model provides a leak-proof heating structure for an immunohistochemical staining machine, comprising: a heating block and a flow guide block connected to the heating block. The heating block is disposed below a glass slide. The connection between the heating block and the flow guide block is provided with a top groove and a bottom groove. The opening of the top groove faces the direction of the glass slide, and the opening of the bottom groove faces away from the direction of the glass slide. The flow guide block is provided with a drain hole, which is located outside the top groove and the bottom groove.
[0006] The heating block includes a support body and a heating film disposed at the bottom of the support body. The top of the support body is provided with a support surface, and the glass slide is placed on the support surface.
[0007] The top slot is lower than the supporting surface, and the bottom slot is parallel to the top slot.
[0008] The drain hole is perpendicular to the support surface of the support body, and the drain hole is vertically opened on the guide block.
[0009] The bottom wall of the bottom slot is further provided with a guide plate on the side near the heating block, and the height of the guide plate is not less than the depth of the bottom slot.
[0010] The top of the guide block is provided with a support position at the same height as the support surface, and the drain hole extends to the support position.
[0011] The top of the guide block is provided with a protruding limiting part, which is located on the top outer wall of the drain hole and is disposed on the side away from the heating block.
[0012] This utility model embodiment also provides a glass slide heating device, which includes a mounting platform and a plurality of immunohistochemical staining machine heating structures as described in any one of the above embodiments disposed on the mounting platform.
[0013] The mounting platform is equipped with a collection tank corresponding to the heating structure of each of the leak-proof immunohistochemical staining machines.
[0014] The bottom of the heating block and the flow guide block are provided with sealant or sealing ring between them and the mounting platform.
[0015] This invention relates to a leak-proof heating structure for an immunohistochemical staining machine. By adding a bottom groove and a guide plate between the heating block and the guide block, it guides and collects reagents and other liquids overflowing from the slide, preventing them from penetrating into the heating membrane and causing damage. This avoids corrosion or peeling of the heating membrane, ensures reliable and efficient heat transfer between the heating membrane and the support, reduces the equipment failure rate, and extends the service life of the immunohistochemical staining equipment.
[0016] The above description is only an overview of the technical solution of this utility model. In order to better understand the technical means of this utility model, it can be implemented according to the contents of the specification. In order to make the above and other objects, features and advantages of this utility model more obvious and easy to understand, the following are preferred embodiments, which are described in detail below. Attached Figure Description
[0017] Figures 1 to 4 These are schematic diagrams of the overall structure of the leak-proof immunohistochemistry staining machine heating structure from different perspectives, representing embodiments of this utility model.
[0018] Figure 5 for Figure 2 A magnified schematic diagram of the central part of the structure.
[0019] Figure 6 for Figure 4 A magnified schematic diagram of the central part of the structure.
[0020] Figure 7 This is a schematic diagram of the overall structure of the glass slide heating device according to an embodiment of the present invention.
[0021] Figure 8 This is an exploded view of the glass slide heating device according to an embodiment of the present invention. Detailed Implementation
[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.
[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.
[0024] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0025] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.
[0026] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.
[0027] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.
[0028] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. The illustrative expressions of the above terms in this specification should not be construed as necessarily referring to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0029] Immunohistochemical staining is a commonly used experimental technique in biomedical research and clinical diagnosis. During the staining process, the heating plate plays a role in maintaining sample temperature and promoting reagent penetration and reaction. Its performance directly affects the staining effect and experimental efficiency. However, existing heating plate designs often have problems with unreasonable drainage port design. When reagents are discharged or overflow, they can easily flow from the drainage port to the area directly below the heating plate, causing the reagents to directly contact and corrode the heating film. This not only reduces heating efficiency but may also cause the heating film to peel off from the aluminum block, increasing equipment failure rate and maintenance costs. Therefore, based on the above requirements, this embodiment provides a leak-proof immunohistochemical staining machine heating structure 10 and its slide heating device 100.
[0030] Please see Figures 1 to 8 This embodiment discloses a leak-proof heating structure 10 for an immunohistochemical staining machine, which includes: a heating block 1 and a flow guide block 2 connected to the heating block 1. The heating block 1 is disposed below a glass slide 20. The connection between the heating block 1 and the flow guide block 2 is provided with a top groove 12 and a bottom groove 23. The opening of the top groove 12 faces the direction of the glass slide 20, and the opening of the bottom groove 23 faces away from the direction of the glass slide 20. The flow guide block 2 is provided with a drain hole 211, which is located outside the top groove 12 and the bottom groove 23.
[0031] The immunohistochemistry staining machine heating structure 10 of this embodiment has a leak-proof design. It has a top slot 12 and a bottom slot 23 with a flow-guiding function and a drain hole 211 between the heating block 1 and the flow guide block 2 to collect the liquid overflowing from the glass slide 20, thereby preventing it from penetrating to the bottom of the heating block 1, corroding the heating film at the bottom of the heating block 1, causing it to detach, and affecting the heat conduction effect.
[0032] The heating block 1 includes a support body 11 and a heating film (not shown) disposed at the bottom 112 of the support body 11. The top of the support body 11 has a support surface 111, on which the glass slide 20 is placed. In this embodiment, the support body 11 is a sheet-like structure, and its support surface 111 is slightly larger than the size of a conventional glass slide; this support surface 111 is a support plane. The support body 11 is generally a rectangular sheet structure. The flow guide block 2 is connected to one of the short sides of the rectangular sheet structure. The bottom 122 of the support body 11 has a mounting groove, in which the heating film is disposed. In this embodiment, the heating block 1 is an aluminum block.
[0033] Please refer to it again. Figure 5 The top slot 12 is lower than the support surface 111, and the bottom slot 23 is arranged parallel to the top slot 12. In this embodiment, both the top slot 12 and the bottom slot 23 extend along the shorter direction of the support body 11.
[0034] The guide block 2 includes a guide block body 21, on which the drain hole 211 is provided.
[0035] The drain hole 211 is perpendicular to the support surface 111 of the support body 11, and the drain hole 211 is vertically opened on the guide block 2. The vertical direction defined in this embodiment refers to the orientation of the heating block 1 when it is in use.
[0036] Please refer to it again. Figure 6 A guide plate 24 protrudes from the bottom wall of the bottom slot 23 near the heating block 1, and the height of the guide plate 24 is not less than the depth of the bottom slot 23. That is, in the case of... Figure 6 In the indicated state, the top edge of the guide plate 24 is not lower than the top edge of the bottom slot 23 in the vertical direction. Figure 6 The state shown is the bottom of the heating block 1 facing upwards, which is exactly the opposite of the actual usage state.
[0037] Please combine again Figure 5The top of the guide block 2 is also provided with a support position 212 at the same height as the support surface 111. The drain hole 211 extends to the support position 212, that is, the top of the drain hole 211 is connected to the support position 212. The support position 212 is a plane formed on the top of the guide block 2. The top slot 12 is recessed between the support position 212 and the support surface 111.
[0038] The top of the guide block 2 is provided with a protruding limiting part 22, which is located on the top outer wall of the drain hole 211 and is positioned away from the heating block 1. When the glass slide 20 is placed on the heating block 1, one side of the glass slide 20 abuts against the limiting part 22, and the bottom of the glass slide 20 is supported on the support surface 111 and the support position 212.
[0039] Please refer to it again. Figure 7 and Figure 8 This embodiment also provides a slide heating device 100, which includes a mounting platform 30 and a plurality of leak-proof immunohistochemical staining machine heating structures 10 as described in any of the above embodiments, disposed on the mounting platform 30.
[0040] The mounting platform 30 is equipped with a collection tank 311 corresponding to each of the leak-proof immunohistochemistry staining machine heating structures 10. To improve the working efficiency of the immunohistochemistry staining machine, the mounting platform 30 has multiple placement positions 31 for placing the leak-proof immunohistochemistry staining machine heating structures 10. Each placement position 31 has a collection tank 311 on its outer side, where liquid overflowing from the leak-proof immunohistochemistry staining machine heating structure 10 is finally collected and stored.
[0041] To improve the sealing performance between the heating structure 10 of the leak-proof immunohistochemistry staining machine and the mounting platform 30, a sealant or sealing ring is also provided between the bottom of the heating block 1 and the guide block 2 and the mounting platform 30.
[0042] Please refer to it again. Figures 1 to 8 The working principle of the glass slide heating device 100 is briefly described below:
[0043] like Figure 7As shown, the slide 20 and the immunohistochemistry staining machine heating structure 10 with anti-leakage are stacked vertically. The rightmost end of the slide 20 is located at the limiting part 22. The bottom of the slide 20 is supported on the support surface 111 and the support position 212. If liquid (such as reagent) overflows from the slide 20, the liquid flows from the top surface of the slide 20 to the right and is guided downward from the drain hole 211 to the collection tank 311. If some liquid leaks and may flow to the bottom of the heating block 1, the bottom groove 23 on the outer side of the guide plate 24 has a guiding function to prevent the liquid from seeping to the left and guide it to the drain hole 211, so as to avoid it flowing to the heating film and damaging the heating film.
[0044] The leakage-proof heating structure of the immunohistochemistry staining machine in this embodiment, by adding a bottom groove and a guide plate between the heating block and the guide block, guides and collects the reagents and other liquids overflowing from the slide, preventing the reagents and other liquids from penetrating into the heating membrane and causing damage to the heating membrane. This avoids corrosion or peeling of the heating membrane, ensures reliable and efficient heat transfer between the heating membrane and the support, reduces the equipment failure rate, and improves the service life of the immunohistochemistry staining equipment.
[0045] The above examples are merely illustrative of the technical content of this utility model to facilitate reader understanding, but do not imply that the implementation of this utility model is limited to these embodiments. Any technical extensions or re-creations made based on this utility model are protected by this utility model. The scope of protection of this utility model is defined by the claims.
Claims
1. A heating structure for an immunohistochemical staining machine with leak-proof design, characterized in that, include: The heating block and the flow guide block connected to the heating block are provided. The heating block is located below the glass slide. The connection between the heating block and the flow guide block is provided with a top groove and a bottom groove. The opening of the top groove faces the direction of the glass slide, and the opening of the bottom groove faces away from the direction of the glass slide. The flow guide block is provided with a drain hole, which is located outside the top groove and the bottom groove.
2. The leak-proof heating structure for an immunohistochemical staining machine according to claim 1, characterized in that, The heating block includes a support body and a heating film disposed at the bottom of the support body. The top of the support body is provided with a support surface, and the glass slide is placed on the support surface.
3. The leak-proof heating structure for an immunohistochemical staining machine according to claim 2, characterized in that, The top slot is lower than the support surface, and the bottom slot is arranged parallel to the top slot.
4. The leak-proof heating structure for an immunohistochemical staining machine according to claim 2, characterized in that, The drain hole is perpendicular to the support surface of the support body, and the drain hole is vertically opened on the guide block.
5. The leak-proof heating structure for an immunohistochemical staining machine according to claim 4, characterized in that, A guide plate is also provided on the bottom wall of the bottom slot near the heating block, and the height of the guide plate is not less than the depth of the bottom slot.
6. The leak-proof heating structure for an immunohistochemical staining machine according to claim 2, characterized in that, The top of the guide block is also provided with a support position at the same height as the support surface, and the drain hole extends to the support position.
7. The leak-proof heating structure for an immunohistochemical staining machine according to claim 6, characterized in that, The top of the guide block is also provided with a protruding limiting part, which is located on the top outer wall of the drain hole and is set on the side away from the heating block.
8. A glass slide heating device, characterized in that, It includes a mounting platform and several leak-proof immunohistochemical staining machine heating structures as described in any one of claims 1 to 7, disposed on the mounting platform.
9. The glass slide heating device according to claim 8, characterized in that, The mounting platform is equipped with a collection tank corresponding to the heating structure of each of the aforementioned leak-proof immunohistochemistry staining machines.
10. The glass slide heating device according to claim 9, characterized in that, A sealant or sealing ring is also provided between the bottom of the heating block and the flow guide block and the mounting platform.