CRYSTALLINE SALT OF 4-(4-(1-ISOPROPYL-7-OXO-1,4,6,7- TETRAHYDRO-SPIRO[INDAZOLE-5,4'-PIPERIDINE]-1'- CARBONYL)-6-METHOXYPYRIDIN-2-YL)BENZOIC ACID WITH 2-AMINO-2-(HYDROXYMETHYL)PRO-PAN-1,3- DIOL

Abstract

The invention provides the tris salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidino]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid as a crystalline anhydrous or trihydrate; as well as polymorphs, pharmaceutical compositions, dosage forms and their use in the treatment of diseases, conditions or disorders regulated by the inhibition of an acetyl-CoA carboxylase (ACC) enzyme(s) in an animal.