Stable suspension concentrate formulation for insecticide

Abstract

The subject matter provided herein provides a stable suspension concentrate insecticidal formulation. The improved physical stability will significantly benefit the overall consistent product quality over the desired shelf-life period.

Description

STABLE SUSPENSION CONCENTRATE FORMULATION FOR INSECTICIDECROSS-REFERENCES TO RELATED APPLICATIONS

[0001] This application claims the benefit of, and priority from, U.S. provisional applications serial number 63 / 632,916, filed on April 11, 2024.FIELD OF THIS DISCLOSURE

[0002] The subject matter provided herein provides a stable suspension concentrate insecticidal formulation. The improved physical stability will significantly benefit the overall consistent product quality over the desired shelf-life period.BACKGROUND

[0003] Despite high water solubility of an active ingredient, the desired formulation type for targeted market could be the suspension concentrate (SC). Suspension concentrate formulations of Tiapyrachlor had been prepared for a number of field trials where a consistent efficacy has been observed. However, the prepared SC formulations suffered an increased in particle size due to particle agglomeration after storage for two weeks at 54 °C. This poses challenges and concerns for long term storage stability and actual product shelf life.SUMMARY

[0004] Recognized herein is a need for a better suspension concentrate formulation. The subject matter provided herein provides a stable suspension concentrate insecticidal formulation. The improved physical stability will significantly benefit the overall consistent product quality over the desired shelf-life period.

[0005] An aspect of the disclosure provides a suspension concentrate insecticidal formulation comprising: (a) at least a water-soluble active ingredient, where water solubility of the active ingredient is from about 0.3 g / L to about 30 g / L at 25 °C; (b) at least one anionic or nonionic dispersant from about 1 to about 15 weight percent of the insecticidal formulation; and (c) optionally a second anionic or nonionic dispersant, where the second dispersant comprises from about 0 to about 10 weight percent of the insecticidal formulation. In some embodiments, the water-soluble active ingredient is Tiapyrachlor. In some embodiments, the suspension concentrate insecticidal formulation comprises the active ingredient from about 1% to about 45% by weight. In some embodiments, the suspension concentrate insecticidal formulation further comprises a second active ingredient selected from groups comprising sulfoxaflor, triflumezopyrim, acetamiprid, clothianidin, dicloromezotiaz, dinotefuran, fenmezoditiaz, flupyradifurone, flupyrimin, imidacloprid, nitenpyram, nicotine, spinetoram, spinosad, N-(2- fluoro-4-{ l-[4-(trifluoromethoxy)phenyl]-l / / -l,2,4-triazol-3-yl}phenyl)-A'-[(2Z)-3-{5-methyl-2- [(2,2,2-trifluoroethoxy)methyl]phenyl}-4-oxo-l,3-thiazolidin-2-ylidene]urea, thiamethoxam, or combination thereof. In some embodiments, the ratio of the water-soluble active ingredient to the second active ingredient is from 100:1 to 1 : 100 by weight. In some embodiments, the dispersant (b) is selected from groups comprising naphthalene sulfonate condensate, lignosulfonate, acrylate copolymer, polymethylmethacrylate, polymeric phenyl glycidyl ether, polymeric amphoteric dispersant or ethoxylated phosphate ester. In some embodiments, the dispersant (b) is sodium alkylnaphthalene sulfonate condensate, polymeric phenyl glycidyl ether, or polymeric amphoteric dispersant. In some embodiments, the second anionic or nonionic dispersant (c) is selected from group comprising sodium lignosulfonate, Kraft lignosulfonate, polyoxypropylenepolyoxyethylene block copolymer, ethoxylated tristyrylphenols, polymethyl methacrylatepolyethylene glycol graft copolymer, ethylene oxide-styrene oxide copolymer monooctyl ether, polymer with oxirane, mono(3, 5, 5 -trimethylhexyl) ether, EO / PO Block monobutyl ether, polymeric ester, or combinations thereof. In some embodiments, the suspension concentrate insecticidal formulation composition comprises the dispersant (c) from about 1% to about 8% by weight. In some embodiments, the suspension concentrate insecticidal formulation comprises weight ratio of the dispersants (b):(c) from about 1 :5 to about 5: 1. In some embodiments, thesuspension concentrate insecticidal formulation further comprises an antifreeze agent, an antifoam agent, one or more antimicrobial agents, one or more thickeners, a solvent, or a combination thereof. In some embodiments, the suspension concentrate insecticidal formulation further comprises a built-in adjuvant comprising canola oil, methyl soyate oil, polyethylene (20) sorbitan, white mineral oil, bio-based oil, tris-2(ethylhexyl) phosphate, alcohols ethoxylated propoxylated, or combination thereof. In some embodiments, the suspension concentrate insecticidal formulation comprises the antimicrobial agents from 0.01% to 2.00% by weight. In some embodiments, the suspension concentrate insecticidal formulation comprises the thickeners from 0.1% to 2.0% by weight.BRIEF DESCRIPTION OF THE DRAWING(S)

[0006] The novel features of the invention are set forth with particularity in the appended claims. A better understanding of the features and advantages of the present invention will be obtained by reference to the following detailed description that sets forth illustrative embodiments, in which the principles of the invention are utilized, and the accompanying drawings of which:

[0007] Fig. 1 shows dispersant screening to overcome particle agglomeration as illustrated in Example 1.

[0008] Fig. 2 shows optical microscopy images of Formulation 1-3 after accelerated storage 54 °C for 2 weeks as illustrated in Example 3.

[0009] Fig. 3 shows particle size distribution comparison as illustrated in Example 5.

[0010] Fig. 4 shows dispersant screening to overcome particle agglomeration as illustrated in Example 7.

[0011] Fig. 5 shows optical microscopy images of formulations after accelerated storage at 54 °C for 2 weeks as illustrated in Example 8.

[0012] Fig. 6 shows optical microscopy images of formulations after accelerated storage at 54 °C for 2 weeks as illustrated in Example 8.

[0013] Fig. 7 shows optical microscopy images of formulations after accelerated storage at 54 °C for 2 weeks as illustrated in Example 8.DETAILED DESCRIPTION

[0014] While various embodiments of the invention have been shown and described herein, it will be obvious to those skilled in the art that such embodiments are provided by way of example only. Numerous variations, changes, and substitutions may occur to those skilled in the art without departing from the invention. It should be understood that various alternatives to the embodiments of the invention described herein may be employed.

[0015] The use of the terms “a”, “an”, “the”, “at least one” and similar referents in the context of describing the invention (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The use of the term “at least one” followed by a list of one or more items (for example, “at least one of A and B”) is to be construed to mean one item selected from the listed items (A or B) or any combination of two or more of the listed items (A and B), unless otherwise indicated herein or clearly contradicted by context. The term "about" when referring to a number or a numerical range means that the number or numerical range referred to is an approximation within experimental variability (or within statistical experimental error), and thus the number or numerical range, in some instances, will vary between 1% and 15% of the stated number or numerical range. The terms “comprising,” “having,” “including,” and “containing” are to be construed as open-ended terms (i.e., meaning “including, but not limited to,”) unless otherwise noted. Recitation of ranges of values herein are merely intended to serve as a shorthand method of referring individually to each separate value falling within the range, unless otherwise indicated herein, and each separate value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g., “such as”) provided herein, is intended merely to better illuminate the invention and does not pose a limitation on the scope of the invention unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the invention.

[0016] The phrase “active ingredient” means a material having activity useful in controlling pests, and / or that is useful in helping other materials have better activity in controlling pests. Examples of such materials include, but are not limited to, acaricides, algicides, antifeedants, avicides, bactericides, bird repellents, chemosterilants, fungicides, herbicide safeners, herbicides, insect attractants, insect repellents, insecticides, mammal repellents, mating disrupters, molluscicides, nematicides, plant activators, plant growth regulators, rodenticides, synergists, and virucides (see alanwood.net).

[0017] Recognized herein is an ongoing need for a stable suspension concentrate formulation. The subject matter provided herein provides a stable suspension concentrate insecticidal formulation. The improved physical stability will significantly benefit the overall consistent product quality over the desired shelf-life period.Water solubility

[0018] In one aspect, provided herein is a suspension concentrate (SC) insecticidal formulation comprising an active ingredient. Water solubility of insecticides may be classified as low (less than 0.01 grams per liter (g / L) or 10 parts per million (ppm)), moderate (0.01 to 1 g / L or 10 to 1,000 ppm), or high (more than 1 g / L or 1,000 ppm) at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is moderate or high.

[0019] In some embodiments, water solubility of the active ingredient in the suspension concentrate (SC) insecticidal formulation is from about 0.3 g / L to about 30 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 0.3 g / L to about 0.4 g / L, from about 0.3 g / L to about 0.5 g / L, from about 0.3 g / L to about 0.6 g / L, from about 0.3 g / L to about 0.8 g / L, from about 0.3 g / L to about 1.0 g / L, from about 0.3 g / L to about 1.2 g / L, from about 0.3 g / L to about 1.4 g / L, from about 0.3 g / L to about 1.6 g / L, from about 0.3 g / L to about 1.8 g / L, from about 0.3 g / L to about 2.0 g / L, from about 0.3 g / L to about 2.2 g / L, from about 0.3 g / L to about 2.4 g / L, from about 0.3 g / L to about 2.6 g / L, from about 0.3 g / L to about 2.8 g / L, from about 0.3 g / L to about 3.0 g / L, from about 0.3 g / L to about 3.5 g / L, from about 0.3 g / L to about 4.0 g / L, from about 0.3 g / L to about 4.5 g / L, from about 0.3 g / L to about 5.0 g / L, from about 0.3 g / L to about 6.0 g / L, from about 0.3 g / L to about 7.0 g / L,from about 0.3 g / L to about 8.0 g / L, from about 0.3 g / L to about 9.0 g / L, from about 0.3 g / L to about 10.0 g / L, from about 0.3 g / L to about 12.0 g / L, from about 0.3 g / L to about 14.0 g / L, from about 0.3 g / L to about 16.0 g / L, from about 0.3 g / L to about 18.0 g / L, from about 0.3 g / L to about 20.0 g / L, from about 0.3 g / L to about 22.0 g / L, from about 0.3 g / L to about 24.0 g / L, from about 0.3 g / L to about 26.0 g / L, from about 0.3 g / L to about 28.0 g / L, or from about 0.3 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 0.4 g / L to about 0.5 g / L, from about 0.4 g / L to about 0.6 g / L, from about 0.4 g / L to about 0.8 g / L, from about 0.4 g / L to about 1.0 g / L, from about 0.4 g / L to about 1.2 g / L, from about 0.4 g / L to about 1.4 g / L, from about 0.4 g / L to about 1.6 g / L, from about 0.4 g / L to about 1.8 g / L, from about 0.4 g / L to about 2.0 g / L, from about 0.4 g / L to about 2.2 g / L, from about 0.4 g / L to about 2.4 g / L, from about 0.4 g / L to about 2.6 g / L, from about 0.4 g / L to about 2.8 g / L, from about 0.4 g / L to about 3.0 g / L, from about 0.4 g / L to about 3.5 g / L, from about 0.4 g / L to about 4.0 g / L, from about 0.4 g / L to about 4.5 g / L, from about 0.4 g / L to about 5.0 g / L, from about 0.4 g / L to about 6.0 g / L, from about 0.4 g / L to about 7.0 g / L, from about 0.4 g / L to about 8.0 g / L, from about 0.4 g / L to about 9.0 g / L, from about 0.4 g / L to about 10.0 g / L, from about 0.4 g / L to about 12.0 g / L, from about 0.4 g / L to about 14.0 g / L, from about 0.4 g / L to about 16.0 g / L, from about 0.4 g / L to about 18.0 g / L, from about 0.4 g / L to about 20.0 g / L, from about 0.4 g / L to about 22.0 g / L, from about 0.4 g / L to about 24.0 g / L, from about 0.4 g / L to about 26.0 g / L, from about 0.4 g / L to about 28.0 g / L, or from about 0.4 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 0.5 g / L to about 0.6 g / L, from about 0.5 g / L to about 0.8 g / L, from about 0.5 g / L to about 1.0 g / L, from about 0.5 g / L to about 1.2 g / L, from about 0.5 g / L to about 1.4 g / L, from about 0.5 g / L to about 1.6 g / L, from about 0.5 g / L to about 1.8 g / L, from about 0.5 g / L to about 2.0 g / L, from about 0.5 g / L to about 2.2 g / L, from about 0.5 g / L to about 2.4 g / L, from about 0.5 g / L to about 2.6 g / L, from about 0.5 g / L to about 2.8 g / L, from about 0.5 g / L to about 3.0 g / L, from about 0.5 g / L to about 3.5 g / L, from about 0.5 g / L to about 4.0 g / L, from about 0.5 g / L to about 4.5 g / L, from about 0.5 g / L to about 5.0 g / L, from about 0.5 g / L to about 6.0 g / L, from about 0.5 g / L to about 7.0 g / L, from about 0.5 g / L to about 8.0 g / L, from about 0.5 g / L to about 9.0 g / L, from about 0.5 g / L to about 10.0 g / L, from about 0.5 g / L to about12.0 g / L, from about 0.5 g / L to about 14.0 g / L, from about 0.5 g / L to about 16.0 g / L, from about 0.5 g / L to about 18.0 g / L, from about 0.5 g / L to about 20.0 g / L, from about 0.5 g / L to about 22.0 g / L, from about 0.5 g / L to about 24.0 g / L, from about 0.5 g / L to about 26.0 g / L, from about 0.5 g / L to about 28.0 g / L, or from about 0.5 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 0.6 g / L to about 0.8 g / L, from about 0.6 g / L to about 1.0 g / L, from about 0.6 g / L to about 1.2 g / L, from about 0.6 g / L to about 1.4 g / L, from about 0.6 g / L to about 1.6 g / L, from about 0.6 g / L to about 1.8 g / L, from about 0.6 g / L to about 2.0 g / L, from about 0.6 g / L to about 2.2 g / L, from about 0.6 g / L to about 2.4 g / L, from about 0.6 g / L to about 2.6 g / L, from about 0.6 g / L to about 2.8 g / L, from about 0.6 g / L to about 3.0 g / L, from about 0.6 g / L to about 3.5 g / L, from about 0.6 g / L to about 4.0 g / L, from about 0.6 g / L to about 4.5 g / L, from about 0.6 g / L to about 5.0 g / L, from about 0.6 g / L to about 6.0 g / L, from about 0.6 g / L to about 7.0 g / L, from about 0.6 g / L to about 8.0 g / L, from about 0.6 g / L to about 9.0 g / L, from about 0.6 g / L to about 10.0 g / L, from about 0.6 g / L to about 12.0 g / L, from about 0.6 g / L to about 14.0 g / L, from about 0.6 g / L to about 16.0 g / L, from about 0.6 g / L to about 18.0 g / L, from about 0.6 g / L to about 20.0 g / L, from about 0.6 g / L to about 22.0 g / L, from about 0.6 g / L to about 24.0 g / L, from about 0.6 g / L to about 26.0 g / L, from about 0.6 g / L to about 28.0 g / L, or from about 0.6 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 0.8 g / L to about 1.0 g / L, from about 0.8 g / L to about 1.2 g / L, from about 0.8 g / L to about 1.4 g / L, from about 0.8 g / L to about 1.6 g / L, from about 0.8 g / L to about 1.8 g / L, from about 0.8 g / L to about 2.0 g / L, from about 0.8 g / L to about 2.2 g / L, from about 0.8 g / L to about 2.4 g / L, from about 0.8 g / L to about 2.6 g / L, from about 0.8 g / L to about 2.8 g / L, from about 0.8 g / L to about 3.0 g / L, from about 0.8 g / L to about 3.5 g / L, from about 0.8 g / L to about 4.0 g / L, from about 0.8 g / L to about 4.5 g / L, from about 0.8 g / L to about 5.0 g / L, from about 0.8 g / L to about 6.0 g / L, from about 0.8 g / L to about 7.0 g / L, from about 0.8 g / L to about 8.0 g / L, from about 0.8 g / L to about 9.0 g / L, from about 0.8 g / L to about 10.0 g / L, from about 0.8 g / L to about 12.0 g / L, from about 0.8 g / L to about 14.0 g / L, from about 0.8 g / L to about 16.0 g / L, from about 0.8 g / L to about 18.0 g / L, from about 0.8 g / L to about 20.0 g / L, from about 0.8 g / L to about 22.0 g / L, from about 0.8 g / L to about 24.0 g / L, from about 0.8 g / L to about 26.0 g / L, from about 0.8g / L to about 28.0 g / L, or from about 0.8 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 1.0 g / L to about 1.2 g / L, from about 1.0 g / L to about 1.4 g / L, from about 1.0 g / L to about 1.6 g / L, from about 1.0 g / L to about 1.8 g / L, from about 1.0 g / L to about 2.0 g / L, from about 1.0 g / L to about 2.2 g / L, from about 1.0 g / L to about 2.4 g / L, from about 1.0 g / L to about 2.6 g / L, from about 1.0 g / L to about 2.8 g / L, from about 1.0 g / L to about 3.0 g / L, from about 1.0 g / L to about 3.5 g / L, from about 1.0 g / L to about 4.0 g / L, from about 1.0 g / L to about 4.5 g / L, from about 1.0 g / L to about 5.0 g / L, from about 1.0 g / L to about 6.0 g / L, from about 1.0 g / L to about 7.0 g / L, from about 1.0 g / L to about 8.0 g / L, from about 1.0 g / L to about 9.0 g / L, from about 1.0 g / L to about 10.0 g / L, from about 1.0 g / L to about 12.0 g / L, from about 1.0 g / L to about 14.0 g / L, from about 1.0 g / L to about 16.0 g / L, from about 1.0 g / L to about 18.0 g / L, from about 1.0 g / L to about 20.0 g / L, from about 1.0 g / L to about 22.0 g / L, from about 1.0 g / L to about 24.0 g / L, from about 1.0 g / L to about 26.0 g / L, from about 1.0 g / L to about 28.0 g / L, or from about 1.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 1.2 g / L to about 1.4 g / L, from about 1.2 g / L to about 1.6 g / L, from about 1 .2 g / L to about 1 .8 g / L, from about 1 .2 g / L to about 2.0 g / L, from about 1 .2 g / L to about 2.2 g / L, from about 1.2 g / L to about 2.4 g / L, from about 1.2 g / L to about 2.6 g / L, from about 1.2 g / L to about 2.8 g / L, from about 1.2 g / L to about 3.0 g / L, from about 1.2 g / L to about 3.5 g / L, from about 1.2 g / L to about 4.0 g / L, from about 1.2 g / L to about 4.5 g / L, from about 1.2 g / L to about 5.0 g / L, from about 1.2 g / L to about 6.0 g / L, from about 1.2 g / L to about 7.0 g / L, from about 1.2 g / L to about 8.0 g / L, from about 1.2 g / L to about 9.0 g / L, from about 1.2 g / L to about 10.0 g / L, from about 1.2 g / L to about 12.0 g / L, from about 1.2 g / L to about 14.0 g / L, from about 1.2 g / L to about 16.0 g / L, from about 1.2 g / L to about 18.0 g / L, from about 1.2 g / L to about 20.0 g / L, from about 1.2 g / L to about 22.0 g / L, from about 1.2 g / L to about 24.0 g / L, from about 1.2 g / L to about 26.0 g / L, from about 1.2 g / L to about 28.0 g / L, or from about 1.2 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 1.4 g / L to about 1.6 g / L, from about 1.4 g / L to about 1.8 g / L, from about 1.4 g / L to about 2.0 g / L, from about 1.4 g / L to about 2.2 g / L, from about 1.4 g / L to about 2.4 g / L, from about 1.4 g / L to about 2.6 g / L, from about 1.4 g / L to about 2.8 g / L, fromabout 1.4 g / L to about 3.0 g / L, from about 1.4 g / L to about 3.5 g / L, from about 1.4 g / L to about 4.0 g / L, from about 1.4 g / L to about 4.5 g / L, from about 1.4 g / L to about 5.0 g / L, from about 1.4 g / L to about 6.0 g / L, from about 1.4 g / L to about 7.0 g / L, from about 1.4 g / L to about 8.0 g / L, from about 1.4 g / L to about 9.0 g / L, from about 1.4 g / L to about 10.0 g / L, from about 1.4 g / L to about 12.0 g / L, from about 1.4 g / L to about 14.0 g / L, from about 1.4 g / L to about 16.0 g / L, from about 1.4 g / L to about 18.0 g / L, from about 1.4 g / L to about 20.0 g / L, from about 1.4 g / L to about 22.0 g / L, from about 1.4 g / L to about 24.0 g / L, from about 1.4 g / L to about 26.0 g / L, from about 1.4 g / L to about 28.0 g / L, or from about 1.4 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 1.6 g / L to about 1.8 g / L, from about 1.6 g / L to about 2.0 g / L, from about 1.6 g / L to about 2.2 g / L, from about 1.6 g / L to about 2.4 g / L, from about 1.6 g / L to about 2.6 g / L, from about 1.6 g / L to about 2.8 g / L, from about 1.6 g / L to about 3.0 g / L, from about 1.6 g / L to about 3.5 g / L, from about 1.6 g / L to about 4.0 g / L, from about 1.6 g / L to about 4.5 g / L, from about 1.6 g / L to about 5.0 g / L, from about 1.6 g / L to about 6.0 g / L, from about 1.6 g / L to about 7.0 g / L, from about 1.6 g / L to about 8.0 g / L, from about 1.6 g / L to about 9.0 g / L, from about 1.6 g / L to about 10.0 g / L, from about 1 .6 g / L to about 12.0 g / L, from about 1 .6 g / L to about 14.0 g / L, from about 1.6 g / L to about 16.0 g / L, from about 1.6 g / L to about 18.0 g / L, from about 1.6 g / L to about 20.0 g / L, from about 1.6 g / L to about 22.0 g / L, from about 1.6 g / L to about 24.0 g / L, from about 1.6 g / L to about 26.0 g / L, from about 1.6 g / L to about 28.0 g / L, or from about 1.6 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 1.8 g / L to about 2.0 g / L, from about 1.8 g / L to about 2.2 g / L, from about 1.8 g / L to about 2.4 g / L, from about 1.8 g / L to about 2.6 g / L, from about 1.8 g / L to about 2.8 g / L, from about 1.8 g / L to about 3.0 g / L, from about 1.8 g / L to about 3.5 g / L, from about 1.8 g / L to about 4.0 g / L, from about 1.8 g / L to about 4.5 g / L, from about 1.8 g / L to about 5.0 g / L, from about 1.8 g / L to about 6.0 g / L, from about 1.8 g / L to about 7.0 g / L, from about 1.8 g / L to about 8.0 g / L, from about 1.8 g / L to about 9.0 g / L, from about 1.8 g / L to about 10.0 g / L, from about 1.8 g / L to about 12.0 g / L, from about 1.8 g / L to about 14.0 g / L, from about 1.8 g / L to about 16.0 g / L, from about 1.8 g / L to about 18.0 g / L, from about 1.8 g / L to about 20.0 g / L, from about 1.8 g / L to about 22.0 g / L, from about 1.8 g / L to about 24.0 g / L, from about 1.8 g / L toabout 26.0 g / L, from about 1.8 g / L to about 28.0 g / L, or from about 1.8 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 2.0 g / L to about 2.2 g / L, from about 2.0 g / L to about 2.4 g / L, from about 2.0 g / L to about 2.6 g / L, from about 2.0 g / L to about 2.8 g / L, from about 2.0 g / L to about 3.0 g / L, from about 2.0 g / L to about 3.5 g / L, from about 2.0 g / L to about 4.0 g / L, from about 2.0 g / L to about 4.5 g / L, from about 2.0 g / L to about 5.0 g / L, from about 2.0 g / L to about 6.0 g / L, from about 2.0 g / L to about 7.0 g / L, from about 2.0 g / L to about 8.0 g / L, from about 2.0 g / L to about 9.0 g / L, from about 2.0 g / L to about 10.0 g / L, from about 2.0 g / L to about 12.0 g / L, from about 2.0 g / L to about 14.0 g / L, from about 2.0 g / L to about 16.0 g / L, from about 2.0 g / L to about 18.0 g / L, from about 2.0 g / L to about 20.0 g / L, from about 2.0 g / L to about 22.0 g / L, from about 2.0 g / L to about 24.0 g / L, from about 2.0 g / L to about 26.0 g / L, from about 2.0 g / L to about 28.0 g / L, or from about 2.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 2.2 g / L to about 2.4 g / L, from about 2.2 g / L to about 2.6 g / L, from about 2.2 g / L to about 2.8 g / L, from about 2.2 g / L to about 3.0 g / L, from about 2.2 g / L to about 3.5 g / L, from about 2.2 g / L to about 4.0 g / L, from about 2.2 g / L to about 4.5 g / L, from about 2.2 g / L to about 5.0 g / L, from about 2.2 g / L to about 6.0 g / L, from about 2.2 g / L to about 7.0 g / L, from about 2.2 g / L to about 8.0 g / L, from about 2.2 g / L to about 9.0 g / L, from about 2.2 g / L to about 10.0 g / L, from about 2.2 g / L to about 12.0 g / L, from about 2.2 g / L to about 14.0 g / L, from about 2.2 g / L to about 16.0 g / L, from about 2.2 g / L to about 18.0 g / L, from about 2.2 g / L to about 20.0 g / L, from about 2.2 g / L to about 22.0 g / L, from about 2.2 g / L to about 24.0 g / L, from about 2.2 g / L to about 26.0 g / L, from about 2.2 g / L to about 28.0 g / L, or from about 2.2 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 2.4 g / L to about 2.6 g / L, from about 2.4 g / L to about 2.8 g / L, from about 2.4 g / L to about 3.0 g / L, from about 2.4 g / L to about 3.5 g / L, from about 2.4 g / L to about 4.0 g / L, from about 2.4 g / L to about 4.5 g / L, from about 2.4 g / L to about 5.0 g / L, from about 2.4 g / L to about 6.0 g / L, from about 2.4 g / L to about 7.0 g / L, from about 2.4 g / L to about 8.0 g / L, from about 2.4 g / L to about 9.0 g / L, from about 2.4 g / L to about 10.0 g / L, from about 2.4 g / L to about 12.0 g / L, from about 2.4 g / L to about 14.0 g / L, from about 2.4 g / L to about 16.0 g / L, from about 2.4 g / L toabout 18.0 g / L, from about 2.4 g / L to about 20.0 g / L, from about 2.4 g / L to about 22.0 g / L, from about 2.4 g / L to about 24.0 g / L, from about 2.4 g / L to about 26.0 g / L, from about 2.4 g / L to about 28.0 g / L, or from about 2.4 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 2.6 g / L to about 2.8 g / L, from about 2.6 g / L to about 3.0 g / L, from about 2.6 g / L to about 3.5 g / L, from about 2.6 g / L to about 4.0 g / L, from about 2.6 g / L to about 4.5 g / L, from about 2.6 g / L to about 5.0 g / L, from about 2.6 g / L to about 6.0 g / L, from about 2.6 g / L to about 7.0 g / L, from about 2.6 g / L to about 8.0 g / L, from about 2.6 g / L to about 9.0 g / L, from about 2.6 g / L to about 10.0 g / L, from about 2.6 g / L to about 12.0 g / L, from about 2.6 g / L to about 14.0 g / L, from about 2.6 g / L to about 16.0 g / L, from about 2.6 g / L to about 18.0 g / L, from about 2.6 g / L to about 20.0 g / L, from about 2.6 g / L to about 22.0 g / L, from about 2.6 g / L to about 24.0 g / L, from about 2.6 g / L to about 26.0 g / L, from about 2.6 g / L to about 28.0 g / L, or from about 2.6 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 2.8 g / L to about 3.0 g / L, from about 2.8 g / L to about 3.5 g / L, from about 2.8 g / L to about 4.0 g / L, from about 2.8 g / L to about 4.5 g / L, from about 2.8 g / L to about 5.0 g / L, from about 2.8 g / L to about 6.0 g / L, from about 2.8 g / L to about 7.0 g / L, from about 2.8 g / L to about 8.0 g / L, from about 2.8 g / L to about 9.0 g / L, from about 2.8 g / L to about 10.0 g / L, from about 2.8 g / L to about 12.0 g / L, from about 2.8 g / L to about 14.0 g / L, from about 2.8 g / L to about 16.0 g / L, from about 2.8 g / L to about 18.0 g / L, from about 2.8 g / L to about 20.0 g / L, from about 2.8 g / L to about 22.0 g / L, from about 2.8 g / L to about 24.0 g / L, from about 2.8 g / L to about 26.0 g / L, from about 2.8 g / L to about 28.0 g / L, or from about 2.8 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 3.0 g / L to about 3.5 g / L, from about 3.0 g / L to about 4.0 g / L, from about 3.0 g / L to about 4.5 g / L, from about 3.0 g / L to about 5.0 g / L, from about 3.0 g / L to about 6.0 g / L, from about 3.0 g / L to about 7.0 g / L, from about 3.0 g / L to about 8.0 g / L, from about 3.0 g / L to about 9.0 g / L, from about 3.0 g / L to about 10.0 g / L, from about 3.0 g / L to about 12.0 g / L, from about 3.0 g / L to about 14.0 g / L, from about 3.0 g / L to about 16.0 g / L, from about 3.0 g / L to about 18.0 g / L, from about 3.0 g / L to about 20.0 g / L, from about 3.0 g / L to about 22.0 g / L, from about 3.0 g / L to about 24.0 g / L, from about 3.0 g / L to about 26.0 g / L, from about 3.0 g / L toabout 28.0 g / L, or from about 3.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 3.5 g / L to about 4.0 g / L, from about 3.5 g / L to about 4.5 g / L, from about 3.5 g / L to about 5.0 g / L, from about 3.5 g / L to about 6.0 g / L, from about 3.5 g / L to about 7.0 g / L, from about 3.5 g / L to about 8.0 g / L, from about 3.5 g / L to about 9.0 g / L, from about 3.5 g / L to about 10.0 g / L, from about3.5 g / L to about 12.0 g / L, from about 3.5 g / L to about 14.0 g / L, from about 3.5 g / L to about 16.0 g / L, from about 3.5 g / L to about 18.0 g / L, from about 3.5 g / L to about 20.0 g / L, from about 3.5 g / L to about 22.0 g / L, from about 3.5 g / L to about 24.0 g / L, from about 3.5 g / L to about 26.0 g / L, from about 3.5 g / L to about 28.0 g / L, or from about 3.5 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 4.0 g / L to about 4.5 g / L, from about 4.0 g / L to about 5.0 g / L, from about 4.0 g / L to about 6.0 g / L, from about 4.0 g / L to about 7.0 g / L, from about 4.0 g / L to about 8.0 g / L, from about 4.0 g / L to about 9.0 g / L, from about 4.0 g / L to about 10.0 g / L, from about 4.0 g / L to about 12.0 g / L, from about 4.0 g / L to about 14.0 g / L, from about 4.0 g / L to about 16.0 g / L, from about 4.0 g / L to about 18.0 g / L, from about 4.0 g / L to about 20.0 g / L, from about 4.0 g / L to about 22.0 g / L, from about 4.0 g / L to about 24.0 g / L, from about 4.0 g / L to about 26.0 g / L, from about 4.0 g / L to about 28.0 g / L, or from about 4.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 4.5 g / L to about 5.0 g / L, from about 4.5 g / L to about 6.0 g / L, from about 4.5 g / L to about 7.0 g / L, from about 4.5 g / L to about 8.0 g / L, from about 4.5 g / L to about 9.0 g / L, from about 4.5 g / L to about 10.0 g / L, from about 4.5 g / L to about 12.0 g / L, from about 4.5 g / L to about 14.0 g / L, from about4.5 g / L to about 16.0 g / L, from about 4.5 g / L to about 18.0 g / L, from about 4.5 g / L to about 20.0 g / L, from about 4.5 g / L to about 22.0 g / L, from about 4.5 g / L to about 24.0 g / L, from about 4.5 g / L to about 26.0 g / L, from about 4.5 g / L to about 28.0 g / L, or from about 4.5 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 5.0 g / L to about 6.0 g / L, from about 5.0 g / L to about 7.0 g / L, from about 5.0 g / L to about 8.0 g / L, from about 5.0 g / L to about 9.0 g / L, from about 5.0 g / L to about 10.0 g / L, from about 5.0 g / L to about 12.0 g / L, from about 5.0 g / L to about 14.0 g / L, from about 5.0 g / L to about 16.0 g / L, from about 5.0 g / L to about 18.0 g / L, from about 5.0 g / L toabout 20.0 g / L, from about 5.0 g / L to about 22.0 g / L, from about 5.0 g / L to about 24.0 g / L, from about 5.0 g / L to about 26.0 g / L, from about 5.0 g / L to about 28.0 g / L, or from about 5.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 6.0 g / L to about 7.0 g / L, from about 6.0 g / L to about 8.0 g / L, from about 6.0 g / L to about 9.0 g / L, from about 6.0 g / L to about 10.0 g / L, from about 6.0 g / L to about 12.0 g / L, from about 6.0 g / L to about 14.0 g / L, from about 6.0 g / L to about 16.0 g / L, from about 6.0 g / L to about 18.0 g / L, from about 6.0 g / L to about 20.0 g / L, from about 6.0 g / L to about 22.0 g / L, from about 6.0 g / L to about 24.0 g / L, from about 6.0 g / L to about 26.0 g / L, from about 6.0 g / L to about 28.0 g / L, or from about 6.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 7.0 g / L to about 8.0 g / L, from about 7.0 g / L to about 9.0 g / L, from about 7.0 g / L to about 10.0 g / L, from about 7.0 g / L to about 12.0 g / L, from about 7.0 g / L to about 14.0 g / L, from about 7.0 g / L to about 16.0 g / L, from about 7.0 g / L to about 18.0 g / L, from about 7.0 g / L to about 20.0 g / L, from about 7.0 g / L to about 22.0 g / L, from about 7.0 g / L to about 24.0 g / L, from about 7.0 g / L to about 26.0 g / L, from about 7.0 g / L to about 28.0 g / L, or from about 7.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 8.0 g / L to about 9.0 g / L, from about 8.0 g / L to about 10.0 g / L, from about 8.0 g / L to about 12.0 g / L, from about 8.0 g / L to about 14.0 g / L, from about 8.0 g / L to about 16.0 g / L, from about 8.0 g / L to about 18.0 g / L, from about 8.0 g / L to about 20.0 g / L, from about 8.0 g / L to about 22.0 g / L, from about 8.0 g / L to about 24.0 g / L, from about 8.0 g / L to about 26.0 g / L, from about 8.0 g / L to about 28.0 g / L, or from about 8.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 9.0 g / L to about 10.0 g / L, from about 9.0 g / L to about 12.0 g / L, from about 9.0 g / L to about 14.0 g / L, from about 9.0 g / L to about 16.0 g / L, from about 9.0 g / L to about 18.0 g / L, from about 9.0 g / L to about 20.0 g / L, from about 9.0 g / L to about 22.0 g / L, from about 9.0 g / L to about 24.0 g / L, from about 9.0 g / L to about 26.0 g / L, from about 9.0 g / L to about 28.0 g / L, or from about 9.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 10.0 g / L to about 12.0 g / L, from about 10.0 g / L to about 14.0 g / L, from about 10.0 g / L to about 16.0 g / L,from about 10.0 g / L to about 18.0 g / L, from about 10.0 g / L to about 20.0 g / L, from about 10.0 g / L to about 22.0 g / L, from about 10.0 g / L to about 24.0 g / L, from about 10.0 g / L to about 26.0 g / L, from about 10.0 g / L to about 28.0 g / L, or from about 10.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 12.0 g / L to about 14.0 g / L, from about 12.0 g / L to about 16.0 g / L, from about 12.0 g / L to about 18.0 g / L, from about 12.0 g / L to about 20.0 g / L, from about 12.0 g / L to about 22.0 g / L, from about 12.0 g / L to about 24.0 g / L, from about 12.0 g / L to about 26.0 g / L, from about 12.0 g / L to about 28.0 g / L, or from about 12.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 14.0 g / L to about 16.0 g / L, from about 14.0 g / L to about 18.0 g / L, from about 14.0 g / L to about 20.0 g / L, from about 14.0 g / L to about 22.0 g / L, from about 14.0 g / L to about 24.0 g / L, from about 14.0 g / L to about 26.0 g / L, from about 14.0 g / L to about 28.0 g / L, or from about 14.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 16.0 g / L to about 18.0 g / L, from about 16.0 g / L to about 20.0 g / L, from about 16.0 g / L to about 22.0 g / L, from about 16.0 g / L to about 24.0 g / L, from about 16.0 g / L to about 26.0 g / L, from about 16.0 g / L to about 28.0 g / L, or from about 16.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 18.0 g / L to about 20.0 g / L, from about 18.0 g / L to about 22.0 g / L, from about 18.0 g / L to about 24.0 g / L, from about 18.0 g / L to about 26.0 g / L, from about 18.0 g / L to about 28.0 g / L, or from about 18.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 20.0 g / L to about 22.0 g / L, from about 20.0 g / L to about 24.0 g / L, from about 20.0 g / L to about 26.0 g / L, from about 20.0 g / L to about 28.0 g / L, or from about 20.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 22.0 g / L to about 24.0 g / L, from about 22.0 g / L to about 26.0 g / L, from about 22.0 g / L to about 28.0 g / L, or from about 22.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 24.0 g / L to about 26.0 g / L, from about 24.0 g / L to about 28.0 g / L, or from about 24.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of theactive ingredient in the SC insecticidal formulation is from about 26.0 g / L to about 28.0 g / L, or from about 26.0 g / L to about 30.0 g / L at 25 °C. In some embodiments, water solubility of the active ingredient in the SC insecticidal formulation is from about 28.0 g / L to about 30.0 g / L at 25 °C.

[0020] In some embodiments, water solubility of the active ingredient in the suspension concentrate (SC) insecticidal formulation is at most about 30.0 g / L, at most about 28.0 g / L, at most about 26.0 g / L, at most about 24.0 g / L, at most about 22.0 g / L, at most about 20.0 g / L, at most about 18.0 g / L, at most about 16.0 g / L, at most about 14.0 g / L, at most about 12.0 g / L, at most about 10.0 g / L, at most about 9.0 g / L, at most about 8.0 g / L, at most about 7.0 g / L, at most about 6.0 g / L, at most about 5.0 g / L, at most about 4.5 g / L, at most about 4.0 g / L, at most about 3.5 g / L, at most about 3.0 g / L, at most about 2.8 g / L, at most about 2.6 g / L, at most about 2.4 g / L, at most about 2.2 g / L, at most about 2.0 g / L, at most about 1.8 g / L, at most about 1.6 g / L, at most about 1.4 g / L, at most about 1.2 g / L, at most about 1.0 g / L, at most about 0.8 g / L, at most about 0.6 g / L, at most about 0.5 g / L, at most about 0.4 g / L, or at most about 0.3 g / L at 25 °C.

[0021] In some embodiments, water solubility of the active ingredient in the suspension concentrate (SC) insecticidal formulation is about 0.3 g / L, about 0.4 g / L, about 0.5 g / L, about 0.6 g / L, about 0.8 g / L, about 1.0 g / L, about 1.2 g / L, about 1.4 g / L, about 1.6 g / L, about 1.8 g / L, about 2.0 g / L, about 2.2 g / L, about 2.4 g / L, about 2.6 g / L, about 2.8 g / L, about 3.0 g / L, about 3.5 g / L, about 4.0 g / L, about 4.5 g / L, about 5.0 g / L, about 6.0 g / L, about 7.0 g / L, about 8.0 g / L, about 9.0 g / L, about 10.0 g / L, about 12.0 g / L, about 14.0 g / L, about 16.0 g / L, about 18.0 g / L, about 20.0 g / L, about 22.0 g / L, about 24.0 g / L, about 26.0 g / L, about 28.0 g / L, or about 30.0 g / L at 25 °C.Active ingredient

[0022] In one aspect, provided herein is a suspension concentrate (SC) insecticidal formulation comprising (a) a water-soluble active ingredient. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of acetylcholinesterase (ACHE) inhibitors (IRAC Group 1, https: / / ^In someembodiments, the active ingredient is selected from the class of carbamates (IRAC Group 1A) comprising alanycarb, aldicarb, bendiocarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, xmc, or xylylcarb. In some embodiments, the active ingredient is selected from the class of organophosphates (IRAC Group IB) comprising acephate, azamethiphos, azinphos- methyl, cadusafos, chlorfenvinphos, chlormephos, cyanophos, demeton-S-methyl, diazinon, dichlorvos (DDVP), dicrotophos, dimethoate, dimethylvinphos, disulfoton, famphur, fenamiphos, fenthion, fosthiazate, heptenophos, malathion, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, phenthoate, phosmet, phosphamidon, propetamphos, pyridaphenthion, terbufos, thiometon, trichlorfon, or vamidothion.

[0023] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of sodium channel modulators (IRAC Group 3). In some embodiments, the active ingredient may be selected from the class of pyrethroids and pyrethrins (IRAC Group 3A). In some embodiments, the active ingredient is selected from the class of sodium channel modulators comprising bifenthrin.

[0024] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of nicotinic acetylcholine receptor (nAChR) competitive modulators (IRAC Group 4). In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the nicotinic acetylcholine receptor competitive modulators class of neonicotinoids (Group 4A) comprising acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, or thiamethoxam. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the nicotinic acetylcholine receptor competitive modulators class of nicotine (Group 4B) comprising nicotine. In some embodiments of thesuspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the nicotinic acetylcholine receptor competitive modulators class of the sulfoximines (Group 4C) comprising sulfoxaflor. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the nicotinic acetylcholine receptor competitive modulators class of the butenolides (Group 4D) comprising flupyradifurone. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the nicotinic acetylcholine receptor competitive modulators class of the mesoionics (Group 4E) comprising triflumezopyrim, dicloromezotiaz, fenmezoditiaz, or flupyrimin.

[0025] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of Nicotinic acetylcholine receptor (nAChR) allosteric modulators-Site I (IRAC Group 5). In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of spinosyns comprising spinetoram or spinosad.

[0026] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of miscellaneous non-specific (multi-site) inhibitors (IRAC Group 8). In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of alkyl halides (IRAC Group 8A) comprising methyl bromide or 1,3- dichloropropene. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of chloropicrin (IRAC Group 8B) comprising chloropicrin. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from theclass of fluorides (IRAC Group 8C) comprising cryolite or sulfuryl fluoride. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of borates (IRAC Group 8D) comprising borax, boric acid, disodium octaborate, sodium borate, or sodium metaborate. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of tartar emetic (IRAC Group 8E) comprising tartar emetic. In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of methyl isothiocyanate generators (IRAC Group 8F) comprising dazomet, metam, or methyl isothiocyanate.

[0027] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of chordotonal organ TRPV channel modulators (IRAC Group 9). In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient is selected from the class of pyridine azomethine derivatives (IRAC Group 9B) comprising pymetrozine.

[0028] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of mitochondrial complex IV electron transport inhibitors (IRAC Group 24). In some embodiments, the active ingredient is selected from the class of phosphides (IRAC Group 24A) comprising phosphine, or zinc phosphide. In some embodiments, the active ingredient is selected from the class of cyanides (IRAC Group 24B) comprising calcium cyanide, potassium cyanide, or sodium cyanide.

[0029] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the class of chordotonal organ nicotinamidase inhibitors (IRAC Group 29) comprising flonicamid.

[0030] In some embodiments of the suspension concentrate insecticidal formulation, assuming that water solubility of the active ingredient is moderate or high, the active ingredient may be selected from the group comprising acetamiprid, acetoprole, avermectin, emamectin benzoate, ethiprole, or thiacloprid.

[0031] In some embodiments, the water-soluble active ingredient of the suspension concentrate insecticidal formulation, is selected from the group comprising aldicarb, azamethiphos, butoxycarboxim, carbofura, chloropicrin, dem eton - -m ethyl, 1,3- dichloropropene, dimethoate, ethiofencarb, flonicamid, heptenophos, methyl bromide, methyl isothiocyanate, metolcarb, naled, pirimicarb, propoxur, sulfuryl fluoride, or tiapyrachlor.

[0032] In some embodiments, the suspension concentrate insecticidal formulation further comprises a second active ingredient comprising sulfoxaflor, triflumezopyrim, acetamiprid, clothianidin, dicloromezotiaz, dinotefuran, fenmezoditiaz, flupyradifurone, flupyrimin, imidacloprid, nitenpyram, nicotine, spinetoram, spinosad, JV-(2-fluoro-4-{ l-[4- (trifluoromethoxy)phenyl]-l / / -l,2,4-triazol-3-yl}phenyl)-JV-[(2Z)-3-{5-methyl-2-[(2,2,2- trifluoroethoxy)methyl]phenyl}-4-oxo-l,3-thiazolidin-2-ylidene]urea, thiamethoxam, or combination thereof.

[0033] In one aspect, provided herein is the suspension concentrate (SC) insecticidal formulation comprising the water-soluble active ingredient from about 1% to about 45% by weight. In some embodiments, the SC formulation comprises water-soluble active ingredient from about 1% to about 2%, from about 1% to about 5%, from about 1% to about 6%, from about 1% to about 7%, from about 1% to about 8%, from about 1% to about 9%, from about 1% to about 10%, from about 1% to about 11%, from about 1% to about 12%, from about 1% to about 13%, from about 1% to about 14%, from about 1% to about 15%, from about 1% to about 16%, from about 1% to about 17%, from about 1% to about 18%, from about 1% to about 19%, from about 1% to about 20%, from about 1% to about 21%, from about 1% to about 22%, from about 1% to about 23%, from about 1% to about 24%, from about 1% to about 25%, from about 1% to about 26%, from about 1% to about 27%, from about 1% to about 28%, from about 1% to about 29%, from about 1% to about 30%, from about 1% to about 35%, from about 1% to about 40%, or from about 1% to about 45% by weight. In some embodiments, the SC formulationcomprises water-soluble active ingredient from about 2% to about 5%, from about 2% to about 6%, from about 2% to about 7%, from about 2% to about 8%, from about 2% to about 9%, from about 2% to about 10%, from about 2% to about 11%, from about 2% to about 12%, from about 2% to about 13%, from about 2% to about 14%, from about 2% to about 15%, from about 2% to about 16%, from about 2% to about 17%, from about 2% to about 18%, from about 2% to about 19%, from about 2% to about 20%, from about 2% to about 21%, from about 2% to about 22%, from about 2% to about 23%, from about 2% to about 24%, from about 2% to about 25%, from about 2% to about 26%, from about 2% to about 27%, from about 2% to about 28%, from about 2% to about 29%, from about 2% to about 30%, from about 2% to about 35%, from about 2% to about 40%, or from about 2% to about 45% by weight. In some embodiments, the SC formulation comprises water-soluble active ingredient from about 5% to about 6%, from about 5% to about 7%, from about 5% to about 8%, from about 5% to about 9%, from about 5% to about 10%, from about 5% to about 11%, from about 5% to about 12%, from about 5% to about 13%, from about 5% to about 14%, from about 5% to about 15%, from about 5% to about 16%, from about 5% to about 17%, from about 5% to about 18%, from about 5% to about 19%, from about 5% to about 20%, from about 5% to about 21%, from about 5% to about 22%, from about 5% to about 23%, from about 5% to about 24%, from about 5% to about 25%, from about 5% to about 26%, from about 5% to about 27%, from about 5% to about 28%, from about 5% to about 29%, from about 5% to about 30%, from about 5% to about 35%, from about 5% to about 40%, or from about 5% to about 45% by weight. In some embodiments, the SC formulation comprises water-soluble active ingredient from about 6% to about 7%, from about 6% to about 8%, from about 6% to about 9%, from about 6% to about 10%, from about 6% to about 11%, from about 6% to about 12%, from about 6% to about 13%, from about 6% to about 14%, from about 6% to about 15%, from about 6% to about 16%, from about 6% to about 17%, from about 6% to about 18%, from about 6% to about 19%, from about 6% to about 20%, from about 6% to about 21%, from about 6% to about 22%, from about 6% to about 23%, from about 6% to about 24%, from about 6% to about 25%, from about 6% to about 26%, from about 6% to about 27%, from about 6% to about 28%, from about 6% to about 29%, from about 6% to about 30%, from about 6% to about 35%, from about 6% to about 40%, or from about 6% to about 45% by weight. In someembodiments, the SC formulation comprises the water-soluble active ingredient from about 7% to about 8%, from about 7% to about 9%, from about 7% to about 10%, from about 7% to about 11%, from about 7% to about 12%, from about 7% to about 13%, from about 7% to about 14%, from about 7% to about 15%, from about 7% to about 16%, from about 7% to about 17%, from about 7% to about 18%, from about 7% to about 19%, from about 7% to about 20%, from about 7% to about 21%, from about 7% to about 22%, from about 7% to about 23%, from about 7% to about 24%, from about 7% to about 25%, from about 7% to about 26%, from about 7% to about 27%, from about 7% to about 28%, from about 7% to about 29%, from about 7% to about 30%, from about 7% to about 35%, from about 7% to about 40%, or from about 7% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 8% to about 9%, from about 8% to about 10%, from about 8% to about 11%, from about 8% to about 12%, from about 8% to about 13%, from about 8% to about 14%, from about 8%> to about 15%>, from about 8% to about 16%, from about 8% to about 17%>, from about 8%> to about 18%, from about 8% to about 19%, from about 8% to about 20%, from about 8% to about 21%, from about 8% to about 22%, from about 8% to about 23%>, from about 8% to about 24%, from about 8% to about 25%, from about 8% to about 26%, from about 8% to about 27%, from about 8% to about 28%, from about 8% to about 29%, from about 8% to about 30%, from about 8% to about 35%>, from about 8% to about 40%, or from about 8%> to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 9% to about 10%, from about 9% to about 11%, from about 9% to about 12%, from about 9% to about 13%, from about 9% to about 14%>, from about 9%o to about 15%, from about 9% to about 16%, from about 9% to about 17%, from about 9% to about 18%o, from about 9% to about 19%, from about 9% to about 20%, from about 9% to about 21%, from about 9% to about 22%, from about 9% to about 23%, from about 9%> to about 24%, from about 9% to about 25%, from about 9% to about 26%, from about 9% to about 27%, from about 9% to about 28%, from about 9% to about 29%, from about 9% to about 30%, from about 9% to about 35%, from about 9% to about 40%, or from about 9% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 10% to about 11%, from about 10% to about 12%, from about 10% to about 13%, from about 10% to about 14%, from about 10% toabout 15%, from about 10% to about 16%, from about 10% to about 17%, from about 10% to about 18%, from about 10% to about 19%, from about 10% to about 20%, from about 10% to about 21%, from about 10% to about 22%, from about 10% to about 23%, from about 10% to about 24%, from about 10% to about 25%, from about 10% to about 26%, from about 10% to about 27%, from about 10% to about 28%, from about 10% to about 29%, from about 10% to about 30%, from about 10% to about 35%, from about 10% to about 40%, or from about 10% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 11% to about 12%, from about 11% to about 13%, from about 11% to about 14%, from about 11% to about 15%, from about 11% to about 16%, from about 11% to about 17%, from about 11% to about 18%, from about 11% to about 19%, from about 11% to about 20%, from about 11% to about 21%, from about 11% to about 22%, from about 11% to about 23%, from about 11% to about 24%, from about 11% to about 25%, from about 11% to about 26%, from about 11% to about 27%, from about 11% to about 28%, from about 11% to about 29%, from about 11% to about 30%, from about 11% to about 35%, from about 11% to about 40%, or from about 11% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 12% to about 13%, from about 12% to about 14%, from about 12% to about 15%, from about 12% to about 16%, from about 12% to about 17%, from about 12% to about 18%, from about 12% to about 19%, from about 12% to about 20%, from about 12% to about 21%, from about 12% to about 22%, from about 12% to about 23%, from about 12% to about 24%, from about 12% to about 25%, from about 12% to about 26%, from about 12% to about 27%, from about 12% to about 28%, from about 12% to about 29%, from about 12% to about 30%, from about 12% to about 35%, from about 12% to about 40%, or from about 12% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 13% to about 14%, from about 13% to about 15%, from about 13% to about 16%, from about 13% to about 17%, from about 13% to about 18%, from about 13% to about 19%, from about 13% to about 20%, from about 13% to about 21%, from about 13% to about 22%, from about 13% to about 23%, from about 13% to about 24%, from about 13% to about 25%, from about 13% to about 26%, from about 13% to about 27%, from about 13% to about 28%, from about 13% to about 29%,from about 13% to about 30%, from about 13% to about 35%, from about 13% to about 40%, or from about 13% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 14% to about 15%, from about 14% to about 16%, from about 14% to about 17%, from about 14% to about 18%, from about 14% to about 19%, from about 14% to about 20%, from about 14% to about 21%, from about 14% to about 22%, from about 14% to about 23%, from about 14% to about 24%, from about 14% to about 25%, from about 14% to about 26%, from about 14% to about 27%, from about 14% to about 28%, from about 14% to about 29%, from about 14% to about 30%, from about 14% to about 35%, from about 14% to about 40%, or from about 14% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 15% to about 16%, from about 15% to about 17%, from about 15% to about 18%, from about 15% to about 19%, from about 15% to about 20%, from about 15% to about 21%, from about 15% to about 22%, from about 15% to about 23%, from about 15% to about 24%, from about 15% to about 25%, from about 15% to about 26%, from about 15% to about 27%, from about 15% to about 28%, from about 15% to about 29%, from about 15% to about 30%, from about 15% to about 35%, from about 15% to about 40%, or from about 15% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 16% to about 17%, from about 16% to about 18%, from about 16% to about 19%, from about 16% to about 20%, from about 16% to about 21%, from about 16% to about 22%, from about 16% to about 23%, from about 16% to about 24%, from about 16% to about 25%, from about 16% to about 26%, from about 16% to about 27%, from about 16% to about 28%, from about 16% to about 29%, from about 16% to about 30%, from about 16% to about 35%, from about 16% to about 40%, or from about 16% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 17% to about 18%, from about 17% to about 19%, from about 17% to about 20%, from about 17% to about 21%, from about 17% to about 22%, from about 17% to about 23%, from about 17% to about 24%, from about 17% to about 25%, from about 17% to about 26%, from about 17% to about 27%, from about 17% to about 28%, from about 17% to about 29%, from about 17% to about 30%, from about 17% to about 35%, from about 17% to about 40%, or from about 17% to about 45% byweight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 18% to about 19%, from about 18% to about 20%, from about 18% to about 21%, from about 18% to about 22%, from about 18% to about 23%, from about 18% to about 24%, from about 18% to about 25%, from about 18% to about 26%, from about 18% to about 27%, from about 18% to about 28%, from about 18% to about 29%, from about 18% to about 30%, from about 18% to about 35%, from about 18% to about 40%, or from about 18% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 19% to about 20%, from about 19% to about 21%, from about 19% to about 22%, from about 19% to about 23%, from about 19% to about 24%, from about 19% to about 25%, from about 19% to about 26%, from about 19% to about 27%, from about 19% to about 28%, from about 19%> to about 29%, from about 19% to about 30%, from about 19% to about 35%, from about 19% to about 40%, or from about 19% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 20% to about 21%, from about 20% to about 22%, from about 20% to about 23%, from about 20% to about 24%, from about 20% to about 25%, from about 20% to about 26%, from about 20% to about 27%, from about 20% to about 28%, from about 20% to about 29%, from about 20% to about 30%, from about 20% to about 35%, from about 20% to about 40%, or from about 20% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 21% to about 22%, from about 21% to about 23%, from about 21% to about 24%, from about 21% to about 25%, from about 21% to about 26%, from about 21% to about 27%, from about 21% to about 28%, from about 21% to about 29%, from about 21% to about 30%, from about 21% to about 35%, from about 21% to about 40%, or from about 21% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 22% to about 23%, from about 22% to about 24%, from about 22% to about 25%, from about 22% to about 26%, from about 22% to about 27%, from about 22% to about 28%, from about 22% to about 29%, from about 22% to about 30%, from about 22% to about 35%, from about 22% to about 40%, or from about 22% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 23% to about 24%, from about 23% to about 25%, from about 23% to about 26%, from about 23% toabout 27%, from about 23% to about 28%, from about 23% to about 29%, from about 23% to about 30%, from about 23% to about 35%, from about 23% to about 40%, or from about 23% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 24% to about 25%, from about 24% to about 26%, from about 24% to about 27%, from about 24% to about 28%, from about 24% to about 29%, from about 24% to about 30%, from about 24% to about 35%, from about 24% to about 40%, or from about 24% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 25% to about 26%, from about 25% to about 27%, from about 25% to about 28%, from about 25% to about 29%, from about 25% to about 30%, from about 25% to about 35%, from about 25% to about 40%, or from about 25% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 26% to about 27%, from about 26% to about 28%, from about 26% to about 29%, from about 26% to about 30%, from about 26% to about 35%, from about 26% to about 40%, or from about 26% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 27% to about 28%, from about 27% to about 29%, from about 27% to about 30%, from about 27% to about 35%, from about 27% to about 40%, or from about 27% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 28% to about 29%, from about 28% to about 30%, from about 28% to about 35%, from about 28% to about 40%, or from about 28% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 29% to about 30%, from about 29% to about 35%, from about 29% to about 40%, or from about 29% to about 45% by weight. In some embodiments, the SC formulation comprises the water- soluble active ingredient from about 30% to about 35%, from about 30% to about 40%, or from about 30% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 35% to about 40%, or from about 35% to about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient from about 40% to about 45% by weight.

[0034] In some embodiments, the suspension concentrate (SC) formulation comprises the water-soluble active ingredient about 1%, about 2%, about 5%, about 6%, about 7%, about 8%,about 9%, about 10%, about 11%, about 12%, about 13%, about 14%, about 15%, about 16%, about 17%, about 18%, about 19%, about 20%, about 21%, about 22%, about 23%, about 24%, about 25%, about 26%, about 27%, about 28%, about 29%, about 30%, about 35%, about 40%, or about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient at least about 1%, at least about 2%, at least about 5%, at least about 6%, at least about 7%, at least about 8%, at least about 9%, at least about 10%, at least about 11%, at least about 12%, at least about 13%, at least about 14%, at least about 15%, at least about 16%, at least about 17%, at least about 18%, at least about 19%, at least about 20%, at least about 21%, at least about 22%, at least about 23%, at least about 24%, at least about 25%, at least about 26%, at least about 27%, at least about 28%, at least about 29%, at least about 30%, at least about 35%, at least about 40%, or at least about 45% by weight. In some embodiments, the SC formulation comprises the water-soluble active ingredient at most 45%, at most about 40%, at most about 35%, at most about 30%, at most about 29%, at most about 28%, at most about 27%, at most about 26%, at most about 25%, at most about 24%, at most about 23%, at most about 22%, at most about 21%, at most about 20%, at most about 19%, at most about 18%, at most about 17%, at most about 16%, at most about 15%, at most about 14%, at most about 13%, at most about 12%, at most about 11%, at most about 10%, at most about 9%, at most about 8%, at most about 7%, at most about 6%, at most about 5%, at most about 2%, or at most about 1% by weight.

[0035] In some embodiments, the suspension concentrate (SC) formulation comprises the water-soluble active ingredient and the second active ingredient at a ratio from about 100: 1 to about 1 : 100 by weight. In some embodiments, the suspension concentrate (SC) formulation comprises the water-soluble active ingredient and the second active ingredient at a ratio about 100: 1, about 50: 1, about 20: 1, about 10:1, about 5: 1, about 2: 1, about 1 : 1, about 1 :2, about 1 :5, about 1 : 10, about 1 :20, about 1 :50, or about 1 : 100 by weight.Dispersant

[0036] In one aspect, provided herein is a suspension concentrate (SC) insecticidal formulation comprising (b) at least one dispersant. Dispersants may be used to disperse solidparticles in a liquid (such as a colloid or emulsion) to improve the separation of the particles and prevent them from agglomerating or settling. In some embodiments, at least one dispersant may be used to disperse the active ingredient in the suspension concentrate (SC) formulation.

[0037] Generally, the dispersion process may include the following steps: wetting of the solid particles; breakdown of the solid particles; and stabilization of the dispersion. Dispersant may be used to help wet the solid particle and eliminate air between the solid particles and liquid medium. Dispersants may be absorbed on the surface of the particles with the other end of the molecule exposed and usually charged. Like charges repel, and the independently coated particles repel each other, maintaining uniform dispersity.

[0038] Dispersant molecules may contain ionic water-loving (hydrophilic) and oil-loving (lipophilic) groups. The hydrophobic (lipophilic) part of the molecule may be attracted to the particle and the particle is surrounded with an ionic layer. For example, in aqueous systems, dispersants are applied to disperse the particles and form an affiliation between the particles and the dispersing medium. Hydrophilic-lipophilic balance (HLB) is the balance of the size and strength of the hydrophilic and lipophilic moieties of a dispersant molecule. HLB may represent the oil and water solubility of a dispersant. The balance between the hydrophobic and hydrophilic properties of the molecules may determine the performance of a dispersant agent, for instance the type of emulsion formed.

[0039] In some embodiments, the suspension concentrate (SC) formulation provided herein comprises dispersant to improve the wetting of the active ingredient and enhance stable suspension. Dispersants may be adsorbed onto the active ingredients and hinder close approach of the particles by charge repulsion effects or by steric effects. Examples of ionic dispersants comprise hydroxy functional groups, polyacrylates, polyurethane, fatty acid modified esters, polyacrylic acids, polycarboxylic copolymers, lignins, naphthalene, alkyl sulfates, alkylbenzene sulfonates, or alkyl ether sulfates.

[0040] In some embodiments, the SC formulation provided herein comprises (b) an anionic dispersant. Anionic dispersants may contain anionic functional groups in the molecules. Examples of anionic dispersant comprise sulfonate, phosphate, carboxylate, lignin, naphthalene, humic acid, or polycarboxylic acids. In some embodiments, the anionic dispersant (b) is selectedfrom groups comprising naphthalene sulfonate condensate, lignosulfonate, acrylate copolymer, polymethylmethacrylate, polymeric phenyl glycidyl ether, di-ethyl ethanol amine mono trimerite, polymeric amphoteric dispersant, or ethoxylated phosphate ester.

[0041] In one aspect, provided herein is the suspension concentrate (SC) insecticidal formulation comprising dispersant (b) from about 1% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 1% to about 2%, from about 1% to about 3%, from about 1% to about 4%, from about 1% to about 5%, from about 1% to about 6%, from about 1% to about 7%, from about 1% to about 8%, from about 1% to about 9%, from about 1% to about 10%, from about 1% to about 11%, from about 1% to about 12%, from about 1% to about 13%, from about 1% to about 14%, or from about 1% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 2% to about 3%, from about 2% to about 4%, from about 2% to about 5%, from about 2% to about 6%, from about 2% to about 7%, from about 2% to about 8%, from about 2% to about 9%, from about 2% to about 10%, from about 2% to about 11%, from about 2% to about 12%, from about 2% to about 13%, from about 2% to about 14%, or from about 2% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 3% to about 4%, from about 3% to about 5%, from about 3% to about 6%, from about 3% to about 7%, from about 3% to about 8%, from about 3% to about 9%, from about 3% to about 10%, from about 3% to about 11%, from about 3% to about 12%, from about 3% to about 13%, from about 3% to about 14%, or from about 3% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 4% to about 5%, from about 4% to about 6%, from about 4% to about 7%, from about 4% to about 8%, from about 4% to about 9%, from about 4% to about 10%, from about 4% to about 11%, from about 4% to about 12%, from about 4% to about 13%, from about 4% to about 14%, or from about 4% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 5% to about 6%, from about 5% to about 7%, from about 5% to about 8%, from about 5% to about 9%, from about 5% to about 10%, from about 5% to about 11%, from about 5% to about 12%, from about 5% to about 13%, from about 5% to about 14%, or from about 5% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 6% to about 7%,from about 6% to about 8%, from about 6% to about 9%, from about 6% to about 10%, from about 6% to about 11%, from about 6% to about 12%, from about 6% to about 13%, from about 6% to about 14%, or from about 6% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 7% to about 8%, from about 7% to about 9%, from about 7% to about 10%, from about 7% to about 11%, from about 7% to about 12%, from about 7% to about 13%, from about 7% to about 14%, or from about 7% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 8% to about 9%, from about 8% to about 10%, from about 8% to about 11%, from about 8% to about 12%, from about 8% to about 13%, from about 8% to about 14%, or from about 8% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 9% to about 10%, from about 9% to about 11%, from about 9% to about 12%, from about 9% to about 13%, from about 9% to about 14%, or from about 9% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 10% to about 11%, from about 10% to about 12%, from about 10% to about 13%, from about 10% to about 14%, or from about 10% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 11% to about 12%, from about 1 1% to about 13%, from about 11% to about 14%, or from about 11% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 12% to about 13%, from about 12% to about 14%, or from about 12% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 13% to about 14%, or from about 13% to about 15% by weight. In some embodiments, the SC formulation comprises dispersant (b) from about 14% to about 15% by weight.

[0042] In some embodiments, the suspension concentrate (SC) formulation comprises dispersant (b) about 1%, about 2%, about 3%, about 4%, about 5%, about 6%, about 7%, about 8%, about 9%, about 10%, about 11%, about 12%, about 13%, about 14%, or about 15% by weight. In some embodiments, the SC formulation comprise dispersant (b) at least about 1%, at least about 2%, at least about 3%, at least about 4%, at least about 5%, at least about 6%, at least about 7%, at least about 8%, at least about 9%, at least about 10%, at least about 11%, at least about 12%, at least about 13%, at least about 14%, or at least about 15% by weight. In someembodiments, the SC formulation comprise dispersant (b) at most about 15%, at most about 14%, at most about 13%, at most about 12%, at most about 11%, at most about 10%, at most about 9%, at most about 8%, at most about 7%, at most about 6%, at most about 5%, at most about 4%, at most about 3%, at most about 2% or at most about 1% by weight.

[0043] In one aspect, provided herein is a suspension concentrate (SC) insecticidal formulation comprising (c) optionally a second anionic or nonionic dispersant. Anionic dispersants may contain anionic functional groups in the molecules. Examples of anionic dispersant comprise sulfonate, phosphate, carboxylate, lignin, naphthalene, humic acid, or polycarboxylic acids. Examples of nonionic dispersants comprise ethoxylates, alkoxylates, poly carboxylic copolymers, or alkyl-poly ethyleneglycol.

[0044] In some embodiments, the suspension concentrate (SC) formulation provided herein comprises an optional anionic or nonionic dispersant comprising sodium lignosulfonate, Kraft lignosulfonate, polyoxypropylene-polyoxyethylene block copolymer, polymeric phenyl glycidyl ether, polymeric amphoteric dispersant, EO / PO Block monobutyl ether, Polymeric ester, ethoxylated tri styrylphenols, ethylene oxide-styrene oxide copolymer monooctyl ether, polymer with oxirane, m on o(3, 5, 5 -tri methyl hexyl) ether, or a combination thereof.

[0045] In some embodiments, the suspension concentrate (SC) formulation comprises dispersant (c) about 0%, about 1%, about 2%, about 3%, about 4%, about 5%, about 6%, about 7%, about 8%, about 9%, or about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) at most about 10%, at most about 9%, at most about 8%, at most about 7%, at most about 6%, at most about 5%, at most about 4%, at most about 3%, at most about 2% or at most about 1% by weight.

[0046] In one aspect, provided herein is the suspension concentrate (SC) insecticidal formulation comprising dispersant (c) from about 0% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 1% to about 2%, from about 1% to about 3%, from about 1% to about 4%, from about 1% to about 5%, from about 1% to about 6%, from about 1% to about 7%, from about 1% to about 8%, from about 1% to about 9%, or from about 1% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 2% to about 3%, from about 2% to about 4%, from about2% to about 5%, from about 2% to about 6%, from about 2% to about 7%, from about 2% to about 8%, from about 2% to about 9%, or from about 2% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 3% to about 4%, from about 3% to about 5%, from about 3% to about 6%, from about 3% to about 7%, from about 3% to about 8%, from about 3% to about 9%, or from about 3% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 4% to about 5%, from about 4% to about 6%, from about 4% to about 7%, from about 4% to about 8%, from about 4% to about 9%, or from about 4% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 5% to about 6%, from about 5% to about 7%, from about 5% to about 8%, from about 5% to about 9%, or from about 5% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 6% to about 7%, from about 6% to about 8%, from about 6% to about 9%, or from about 6% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 7% to about 8%, from about 7% to about 9%, or from about 7% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 8% to about 9%, or from about 8% to about 10% by weight. In some embodiments, the SC formulation comprises dispersant (c) from about 9% to about 10% by weight.

[0047] In one aspect, provided herein is the suspension concentrate (SC) insecticidal formulation comprising dispersant (b) and the anionic dispersant (c) at a weight ratio of (b):(c) from about 1 : 10 to about 10: 1. In some embodiments, the weight ratio of (b):(c) in SC insecticidal formulation is about 1 : 10, about 1 :9, about 1 :8, about 1 :7, about 1 :6, about 1 :5, about 1 :4, about 1 :3, about 1 :2, about 1:1, about 2:9, about 2:7, about 2:5, about 2:3, about 2: 1, about 3: 10, about 3:8, about 3:7, about 3:5, about 3:4, about 3:2, about 3: l, about 4:9, about 4:7, about 4:5, about 4:3, about 4: 1, about 5:9, about 5:8, about 5:7, about 5:6, about 5:4, about 5:3, about5:2, about 5:1, about 6:7, about 6:5, about 6:1, about 7:10, about 7:9, about 7:8, about 7:6, about7:5, about 7:4, about 7:3, about 7:2, about 7: 1, about 8:9, about 8:7, about 8:5, about 8:3, about8: 1, about 9:10, about 9:8, about 9:7, about9:5, about 9:4, about 9:2, about 9: 1, about 10:9, about10:7, about 10:3, or about 10:1.

[0048] In some embodiments, the weight ratio of (b):(c) in the SC insecticidal formulation is at least about 1 : 10, at least about 1 :9, at least about 1 :8, at least about 1 :7, at least about 1 :6, at least about 1 :5, at least about 1 :4, at least about 1 :3, at least about 1 :2, at least about 1 : 1, at least about 2:9, at least about 2:7, at least about 2:5, at least about 2:3, at least about 2: 1, at least about 3: 10, at least about 3:8, at least about 3:7, at least about 3:5, at least about 3:4, at least about 3:2, at least about 3: 1, at least about 4:9, at least about 4:7, at least about 4:5, at least about 4:3, at least about 4: 1, at least about 5:9, at least about 5:8, at least about 5:7, at least about 5:6, at least about 5:4, at least about 5:3, at least about 5:2, at least about 5: 1, at least about 6:7, at least about 6:5, at least about 6: 1, at least about 7: 10, at least about 7:9, at least about 7:8, at least about 7:6, at least about 7:5, at least about 7:4, at least about 7:3, at least about 7:2, at least about 7: 1, at least about 8:9, at least about 8:7, at least about 8:5, at least about 8:3, at least about 8: 1, at least about 9: 10, at least about 9:8, at least about 9:7, at least about9:5, at least about 9:4, at least about 9:2, at least about 9: 1, at least about 10:9, at least about 10:7, at least about 10:3, or at least about 10: 1.Diluent

[0049] In one aspect, provided herein a suspension concentrate (SC) insecticidal formulation comprises a diluent. Diluent may be applied to dissolve or dilute the active ingredient and make it easier to apply. Diluent may be applied to affect the effectiveness, safety, and stability of the SC insecticidal formulation.

[0050] Non-limiting examples of diluent comprise water, acetone, acetonitrile, alcohols, cyclohexanone, dimethylformamide (DMF), dimethylsulfoxide (DMSO), or a combination thereof.Adjuvant

[0051] In one aspect, provided herein is the suspension concentrate (SC) insecticidal formulation further comprising adjuvants. An adjuvant may be added as a supplemental substance to an insecticidal formulation to enhance the performance and / or physical properties of the active ingredient. In some embodiments, adjuvant in the SC insecticidal formulationprovided herein comprises antifreeze agents, antifoam agents, thickening agents, antimicrobial agents, or mixtures thereof.

[0052] Exemplary agriculturally acceptable adjuvants comprise polyether polysiloxane, crop oil concentrates (e.g., 85% mineral oil + 15% emulsifiers), nonylphenol ethoxylates, benzylcocoalkyldimethyl quaternary ammonium salts, blends of petroleum hydrocarbon, alkyl esters, organic acids, anionic surfactants, C9-C11 alkylpolyglycoside, phosphate alcohol ethoxylates, natural primary alcohol (C12-C16) ethoxylate, di-sec-butylphenol ethylene oxide / propylene oxide (EO-PO) block copolymers, polysiloxane-methyl cap, mixture of nonylphenol ethoxylate urea ammonium nitrates, emulsified methylated seed oils, tridecyl alcohol (synthetic) ethoxylates (e.g., 8 EO), tallow amine ethoxylates (e.g., 15 EO), or PEG(400) dioleate-99.

[0053] In some embodiments, the SC formulation comprises adjuvant comprising canola oil, methyl soyate oil, polyethylene (20) sorbitan, white mineral oil, bio-based oil, tris-2(ethylhexyl) phosphate, alcohols ethoxylated propoxylated, or combination thereof.

[0054] In some embodiments, the SC formulation provided herein comprises adjuvant comprising naturally derived oils derived from or made from plant or animal sources and include, for example, triglyceride fatty acid esters such as vegetable oils, seed oils, or animal oils, or monoesters derived from vegetable, seed, or animal oils, and mixtures thereof. In some embodiments, the SC formulation provided herein comprises monoesters derived from vegetable, seed, or animal oils include fatty acid alkyl esters such as methyl caproate, methyl caprylate, methyl caprate, methyl laurate, methyl myristate, methyl palmitate, methyl stearate, methyl oleate, methyl linoleate, methyl linolenate, and mixtures thereof. In some embodiments, the SC formulation provided herein comprises triglyceride fatty acid esters include vegetable or a seed oils selected from soybean oil, rape seed oil, olive oil, almond oil, canola oil, omega-9 canola oil, castor oil, sunflower seed oil, coconut oil, corn oil, cotton seed oil, linseed oil, palm oil, peanut oil, safflower oil, sesame oil, tung oil, and mixtures thereof. In some embodiments, the SC formulation provided herein comprises commercially available, naturally derived oils include: Stepan® 108, a caprylic / capric triglyceride and Steposol® C42, a methyl laurate / methyl myristate ester derived fromcoconut oil, which are both available from Stepan (Northfield, Ill.), and Agnique ME12-18, a mixture of Cl 2- 18 fatty acid methyl esters, and Aqnique ME18-U, methyl oleate, which are both available from BASF (Florham Park, N.J.).

[0055] In some embodiments, the SC formulation provided herein comprises petroleum derived oils include aromatic and paraffinic hydrocarbons such as, for example, one or more of petroleum fractions or hydrocarbons such as mineral oil, kerosene, paraffinic oils including normal paraffins, isoparaffins and cycloparaffins, mixed naphthalene and alkyl naphthalene fractions, aromatic solvents, particularly alkyl subtituted benzenes such as xylene or propylbenzene fractions, and the like, and mixtures thereof. In some embodiments, the SC formulation provided herein comprises commercially available petroleum derived oils include: Isopar™ M, Exxsol™ DI 10, Exxsol™ D60, Aromatic 100, and Aromatic 200 which are all available from ExxonMobil Chemical (Houston, Tex.).

[0056] Exemplary agriculturally acceptable adjuvants include, but are not limited to, thickening agents (i.e., thickeners). Exemplary thickeners comprise polysaccharides (e.g., xanthan gum), guar gum, locust bean gum, polyvinylpyrrolidones (PVP), polyvinyl acetates, polyvinyl alcohols, gelatin, carboxy methyl cellulose, sodium carboxymethyl cellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch attapulgite clay, bentonite clay, organic and inorganic sheet minerals, or mixtures thereof. In some embodiments, the suspension concentrate (SC) insecticidal formulation provided herein comprises thickeners from 0.1% to 2.0% by weight.

[0057] Exemplary agriculturally acceptable adjuvants include, but are not limited to, antifreeze agents. Exemplary antifreeze agents comprise ethylene glycol, propylene glycol, propane diols, glycol (e.g., monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol), glycerin, urea, magnesium sulfate heptahydrate, sodium chloride, or mixtures thereof. In some embodiments, the suspension concentrate (SC) insecticidal formulation provided herein comprises antifreeze agent from 1.0% to 12.0% by weight.

[0058] Exemplary agriculturally acceptable adjuvants include, but are not limited to, antifoam agent. Exemplary antifoam agents comprise silicone emulsions, long-chain alcohols, fatty acids, fatty acid salts, polydimethylsiloxane, organofluorine compounds, or mixturesthereof. In some embodiments, the suspension concentrate (SC) insecticidal formulation provided herein comprises antifoam agent from 0. 1% to 1.0% by weight.

[0059] Exemplary agriculturally acceptable adjuvants include, but are not limited to, antimicrobial agents. Exemplary antimicrobial agents include, but are not limited to: bactericides based on dichlorophen and benzyl alcohol hemiformal; isothiazolinone derivatives, such as methylchloroisothiazolinone, alkylisothiazolinones and benzisothiazolinones; and mixtures thereof. In some embodiments, the suspension concentrate (SC) insecticidal formulation provided herein comprises antimicrobial agent from 0.01% to 2.00% by weight.EXAMPLES

[0060] The following examples further illustrate the invention but, of course, should not be construed as in any way limiting its scope.EXAMPLE 1 : Suspension concentrate formulation with one dispersant.

[0061] Suspension concentrate (SC) formulations containing active ingredient (Al) of 240 grams per liter (g / L) and one dispersant of 8% by weight were prepared as listed in Table 1. Zirconium beads (0.8 mm) were used as a grinding media. A grinding speed was set at 1000 rpm. All samples were milled until target particle size of D90 < 10 pm was reached. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 1: Composition of Suspension concentrate (SC) formulation.Dispersant 2

[0062] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. As illustrated in Fig. 1, comparing to the condition at room temperature (RT), one-dispersant formulations with non-ionic organically modified polymer (polymeric dispersant 1) and polymeric phenyl glycidyl ether (polymeric dispersant 2) at 8% by weight provided good particle size control at 54 °C over two weeks. Particle sizes were found increased with agglomeration after storage for two weeks at 54 °C, for one-dispersant formulations with ethoxylated tristyrylphenol, polyether (polymeric dispersant 3), and polyoxypropylene-polyoxyethylene block copolymer at 8% by weight. Particle size was found increased for one-dispersant formulations with sodium naphthalene sulfonate condensate at 8% by weight.EXAMPLE 2: Suspension concentrate formulation with two dispersants.

[0063] Suspension concentrate (SC) formulations containing active ingredient of 240 grams per liter (g / L) with two dispersants were prepared. Zirconium beads (0.8 mm) were used as a grinding media. A grinding speed was set at 1000 rpm. All samples were milled until target particle size of D$>o < 10 pm was reached. All particle size measurements were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).

[0064] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. Results of particle sizes for suspension concentrate formulations with two dispersants were listed in Table 2. Results of particle size observed for one-dispersant formulations with at 8% by weight was also listed in Table 2 as a reference. As illustrated in Table 2, % change in particle size from room temperature (RT) of formulations with sodium naphthalene sulfonate condensate plus another dispersant were better than that with only sodium naphthalene sulfonate condensate, at totaldispersant of 8% by weight. Formulation with 6% sodium naphthalene sulfonate condensate and 2% kraft lignosulfonate by weight provided a stable suspension concentrate formulation at 54 °C for 2 weeks.Table 2. Particle size of suspension concentrate formulation with two dispersants.EXAMPLE 3 : Tiapyrachlor and Sulfoxaflor premix formulation.

[0065] Suspension concentrate (SC) formulations containing active ingredient of 120 grams per liter (g / L) at 1:1 ratio of Tiapyrachlor and Sulfoxaflor with different dispersant packages were prepared as listed in Table 3. Glass beads (1-1.3 mm) were used as a grinding media. A grinding speed was set at 4000 rpm. All samples were milled until target particle size of D90 < 10 pm was reached. Measurements of all particle sizes were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 3: Suspension concentrate (SC) formulations.

[0066] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. As illustrated in Fig. 2, the microscope images showed the agglomeration of particles after storage for two weeks at 54 °C in Formulation 2 (with two anionic dispersants) and Formulation 3 (with a combination of a nonionic and an anionic dispersant). Also as illustrated in Table 4, the particle sizes increased significantly in both Formulation 2 and Formulation 3, after storage for two weeks at 54 °C, comparing to the condition at room temperature (RT). However, Formulation 1 with a single nonionic dispersant (polymeric dispersant 2), provided good particle size control at 54 °C over two weeks.Table 4: Particle size control for suspension concentrate (SC) formulations.EXAMPLE 4: Single dispersant screening for Tiapyrachlor and Sulfoxaflor premix.

[0067] Suspension concentrate (SC) Formulations 4-17 containing active ingredient of 120 grams per liter (g / L) at 1 : 1 ratio of Tiapyrachlor and Sulfoxaflor with one dispersant of 6% by weight were prepared as listed in Table 5. Zirconium beads (0.8 mm) were used as a grinding media. A grinding speed was set at 1000 rpm. All samples were milled until target particle size of D90 < 10 pm was reached. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 5: Composition of suspension concentrate (SC) Formulations 4-17 with dispersant at 6% by weight.

[0068] Samples were placed in an accelerated storage at 54 °C for 1 week. Particle size and physical appearance were monitored before and after storage. As shown in Table 6, significant increase in particle size was observed in most of the Formulations with found agglomeration as well as some crystal growth after storage for one week at 54 °C, comparing to the condition at room temperature (RT). Only Formulation 16 with polymeric dispersant 2 (loading at 6%) continued to provide a good particle size control after storage for one week at 54 °C for 120 g / L total Al loading.Table 6: Particle size control for Formulations 4-17.

[0069] Suspension concentrate (SC) formulations 18-30 containing active ingredient of 240 grams per liter (g / L) at 1 : 1 ratio of Tiapyrachlor and Sulfoxaflor with one dispersant of 9% by weight were prepared as listed in Table 7. Zirconium beads (0.8 mm) were used as a grinding media. A grinding speed was set at 1000 rpm. All samples were milled until target particle size of D90 < 10 pm was reached. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 7: Composition of suspension concentrate (SC) Formulations 18-30 with dispersant at 9% by weight.

[0070] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. As shown in Table 8, significant increase in particle sizes was observed in most Formulations, with found agglomeration as well as some crystal growth after storage for two weeks at 54 °C, comparing to the condition at room temperature (RT). Formulation 18 with polymeric dispersant 2 and Formulation 29 withpolymeric amphoteric dispersant (polymeric dispersant 6) provided a good particle size control after storage for two weeks at 54 °C for 240 g / L total Al loading.Table 8: Particle size control for Formulations 18-30.EXAMPLE 5: Optimization of formulation for Tiapyrachlor and Sulfoxaflor premix with two dispersants (a combination with polymeric dispersant 2),

[0071] Suspension concentrate (SC) formulations containing active ingredient of 240 grams per liter (g / L) at 1 : 1 ratio of Tiapyrachlor and Sulfoxaflor and two dispersants were prepared as listed in Table 9. Polymeric dispersant 2 was fixed at 9 % by weight as main dispersant. The second dispersant was selected from anionic and nonionic dispersants and was fixed at 2% by weight. Zirconium beads (0.8 mm) were used as a grinding media. A grinding speed was set at 1000 rpm. All samples were milled until target particle size of D$>o < 10 pm was reached.Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 9: Composition of selected suspension concentrate (SC) Formulations with two dispersants.

[0072] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. As shown in Table 10, significant increase in particle sizes was observed in most Formulations, with found agglomeration as well as some crystal growth after storage at 54 °C for 2 weeks, comparing to the condition at room temperature (RT). Formulations 31, 37, and 50 having a combination of polymeric dispersant 2 and a nonionic dispersant showed good particle size control after an accelerated storage at 54 °C for 2 weeks. Further, as illustrated in Fig. 3, size classes of particles after storage at 54 °C for 2 weeks were found to be close as those of RT for Formulations 31, 37 and 50.Table 10: Selected particle size control of Formulations.EXAMPLE 6: Addition of built-in Drift Reduction Technology (DRT),

[0073] As shown in Table 11 and Table 12, built-in adjuvants were prepared.Table 11: Compositions of built-in DRT 1-7.Table 12: Compositions of built-in DRT 8-16.

[0074] Suspension concentrate (SC) formulations containing active ingredient of 120 grams per liter (g / L) at 1 : 1 ratio of Tiapyrachlor and Sulfoxaflor and different built-in Drift Reduction Technologies (DRT) were prepared as listed in Tables 13-16. For SC phase, glass beads (1-1.3 mm) were used as a grinding media. A grinding speed was set at 4000 rpm. All samples were milled until target particle size of D90 < 10 pm was reached. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK. Built- in DRT was added as either a pure component or as an oil in water emulsion (EW) formulation. The EW phases were prepared under high shear at 6000-8000 rpm until target particle size of D90 < 4 pm was reached. The final formulation samples were prepared by mixing SC with EW phase or the pure component of DRT. Measurements of all particle sizes were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 13: Composition of suspension concentrate (SC) Formulations 52-58 with built-in DRT.Table 14: Composition of suspension concentrate (SC) Formulations 59-65 with built-in DRT.Table 15: Composition of suspension concentrate (SC) Formulations 66-72 with built-in DRT.Table 16: Composition of suspension concentrate (SC) Formulations 73-79 with built-in DRT.

[0075] Formulations with built-in DRT were further monitored for physical stability.Samples were placed in an accelerated storage at 54 °C for up to 2 weeks. Particle sizes and physical appearance were monitored before and after storage. As shown in Table 17, significant increase in particle sizes was observed for a lot of the samples with found agglomeration as well as some crystal growth after storage for five days or two weeks at 54 °C, comparing to the condition at room temperature (RT). When compared to Formulations without built-in DRT, Formulations 55, 60, 64, 65, 69, 71, 76, and 77 showed little to no agglomeration of the particles similar to what was observed in Formulation 16 (no built-in DRT).Table 17: Particle size control for Formulations with built-in DRT.*: Sizes were measured at 54 °C after storage for 5 days.

[0076] Formulations 52-58 were subjected to a spray droplet characterization. The spray solutions of test formulations were prepared and sprayed through a XR8002 nozzle and an AIXR11004. All the experiments were conducted at 40 PSI. The spray solution was prepared by diluting the formulation to 50 g Tiapyrachlor / ha use rate in 100 L / ha application volume. Drift performance results expressed as % volume of the number of droplets below 150 pm, were listed in Table 18 Formulations 52-58 (all with built-in DRT) showed a significantly lower percentage of fine droplets (below 150 pm) compared to water and Formulation 16 (no built-in DRT).Table 18: Drift performance of Formulations 16 and 52-58.EXAMPLE 7: Formulations for Tiapyrachlor and Spinetoram premix.

[0077] Suspension concentrate (SC) formulations containing active ingredient of 240 grams per liter (g / L) at 1:1 ratio of Tiapyrachlor and Spinetoram with different dispersant packages were prepared as listed in Table 19. Stainless steel beads (1-1.3 mm) were used as a grinding media. A grinding speed was set at 4000 rpm. All samples were milled until target particle size of D$>o < 10 pm was reached. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 19: Suspension concentrate (SC) formulations.

[0078] Samples were placed in an accelerated storage at 54 °C for 2 weeks. Particle size and physical appearance were monitored before and after storage. As illustrated in microscope images of Fig. 4, the agglomeration of particles was observed in Formulations 82 and 83, after storage at 54 °C for two weeks. Formulation 82 contained a single anionic dispersant, and Formulation 83 contained a combination of nonionic and anionic dispersant.

[0079] As shown in Table 20, Formulation 80 with a nonionic dispersant polymeric dispersant 1, Formulation 81 with polymeric dispersant 2, Formulation 84 with combination of a nonionic and an anionic dispersant at 1:3 weight ratio, and Formulation 85 with mixture of a nonionic and two different anionic dispersants at 1 : 1 :5 provided good particle size control at 54 °C over two weeks. Significant increase in particle sizes after storage at 54 °C for 2 weeks, comparing to the condition at room temperature (RT), was observed for Formulation 86 with EO / PO Block, monobutyl ether 1.Table 20: Particle size control and wet sieve for selected Formulations 80-86.EXAMPLE 8: Tiapyrachlor formulations with built-in adjuvant.

[0080] Suspension concentrate (SC) formulations containing active ingredient of 120 grams per liter (g / L) of Tiapyrachlor containing different dispersant packages of 3-6% by weight and built-in adjuvants comprising methyl soyate oil, canola oil, or Polyethylene sorbitan were prepared as listed in Tables 21-24. In SC phase Stainless steel beads (1-1.3 mm) were used as a grinding media, a grinding speed was set at 4000 rpm all samples were milled until target particle size of D$>o < 10 pm was reached. Built-in adjuvant was added as either a pure component or as an oil in water emulsion (EW) formulation. EW phases were prepared under high shear at 6000-8000 rpm until target particle size of Dgo<5 pm was reached. The formulation sample were prepared by mixing SC with EW phase or pure component. Measurements of all particle size were conducted using the Malvern Mastersizer® 3000 (Malvern Instruments Limited, UK).Table 21: Composition of built-in adjuvants with methyl soyate oil or canola oil.Table 22: Composition containing 120g / L Tiapyrachlor with built-in methyl soyate oil.Table 23: Composition containing 120g / L Tiapyrachlor with built-in canola oil.Table 24: Composition containing 120g / L Tiapyrachlor with built-in polyethylene (20) sorbitan.

[0081] Samples were placed in an accelerated storage at 54 °C for 2 weeks and freeze thaw cycles for 2 or 4 weeks. Particle size and physical appearance were monitored before and after storage. Microscope examinations were conducted to monitor particle agglomeration or EW oil coalescence after storage.

[0082] As shown in Table 25, among samples having methyl soyate oil as the built-in adjuvant, Formulation 88 containing combination of sodium naphthalene sulfonate condensate and Kraft lignosulfonate at 1 :3 ratio, and Adjuvant 18 as the built-in adjuvant provided good particle size control and good EW stability after storage at 54 °C for two weeks, as well as after freeze thaw (FT) cycles for 4 weeks. Formulation 87 with a nonionic dispersant polymeric dispersant 2, Formulation 89 with polymeric dispersant 1, Formulation 95 with combination of sodium naphthalene sulfonate condensate and Kraft lignosulfonate at 1 :3 ratio, and Adjuvant 17 as the built-in provided good particle size control after storage at 54 °C for two weeks; however, EW coalescence was observed after storage at freeze thaw condition for 2 or 4 weeks.Formulations 90-92 containing the same adjuvant 19 showed EW coalescence after storage at 54 °C for two weeks and at freeze thaw cycles for 4 weeks. Formulations 93 and 94 with combination of sodium naphthalene sulfonate condensate and polymethyl methacrylatepolyethylene glycol graft copolymer or modified styrene acrylic copolymer 1 at 3: 1 ratio showedthe agglomeration of particles after storage at 54 °C for two weeks, and EW coalescence after storage at freeze thaw cycles for 2 weeks. Significant increase in particle sizes was also observed for both Formulations 93 and 94, comparing to the condition at room temperature (RT), as shown in Table 25.Table 25: Particle size control and wet sieve for selected Formulations with methyl soyate oil as the built-in adjuvant.

[0083] As illustrated in microscope images of Fig. 5, Formulation 88 provided good particle and EW stability. Agglomeration of particles was observed in formulation 93 after storage at 54 °C for two weeks. EW coalescence was observed in Formulation 91.

[0084] As shown in Table 26, among samples having canola oil as the built-in adjuvant, Formulation 97 with polymeric dispersant 2, Formulation 98 and Formulation 106 with polymeric dispersant 1, Formulation 102 with ethoxylated tristyrylphenol phosphate potassium salt all provided good particle size control and EW stability after storage for two weeks at 54 °C and at freeze thaw cycles for 2 or 4 weeks. However, Formulation 106 was found very viscous at room temperature. Formulation 96 with combination of sodium naphthalene sulfonate condensate with Kraft lignosulfonate at 3 : 1 ratio and Formulation 101 with combination of sodium naphthalene sulfonate condensate with modified styrene acrylic copolymer 1 at 3: 1 ratio, showed oil agglomeration at room temperature. Formulation 99 with combination of sodium naphthalene sulfonate condensate and polymethyl methacrylate-polyethylene glycol graft copolymer at 3: 1 ratio, formulation 100 with a nonionic dispersant polymeric dispersant 6, formulation 103 with an anionic dispersant maleic acid, polymer with diisobutene, sodium salt showed the agglomeration of particles after storage at 54 °C for two weeks. Formulation 104 with combination of sodium naphthalene sulfonate condensate and Kraft lignosulfonate at 3 : 1 ratio as dispersant, and Adjuvant 21 as built-in showed EW coalescence after storage at freeze thaw cycles for 4 weeks. Formulation 105 with combination of sodium naphthalene sulfonate condensate and Kraft lignosulfonate at 3: 1 ratio as dispersant, and Adjuvant 22 as built-in showed EW coalescence after storage at 54 °C and freeze thaw cycles for 2 weeks.Table 26: Particle size control and wet sieve for selected Formulations with canola oil as the built-in adjuvant.

[0085] As illustrated in microscope images of Fig. 6, Formulation 97 provided good particle and EW stability. Agglomeration of particles was observed in Formulation 100 after storage at 54 °C for two weeks. EW coalescence was observed in Formulation 105.

[0086] As shown in Table 27, among samples having polyethylene (20) sorbitan as the built- in adjuvant, Formulation 107 with combination of sodium naphthalene sulfonate condensate and Kraft lignosulfonate at 3: 1 ratio as dispersant provided good particle size control after storage at 54 °C for two weeks; however, more than 50% phase separation was found at room temperature and after storage at 54 °C for two weeks. Formulation 110 (with silica as thickener) contained the same dispersant as Formulation 107, provided less particle increase, less than 0.1% wet sieve and less than 5% phase separation after storage at 54 °C for two weeks.

[0087] Formulation 108 with nonionic dispersant polymeric dispersant 2, Formulation 109 with polymeric dispersant 1, Formulation 113 with polymeric dispersant 6, and Formulation 115 with anionic dispersant ethoxylated tri styrylphenol phosphate potassium salt showed agglomeration of particles after storage at 54 °C for two weeks.

[0088] Formulation 111, Formulation 112 and Formulation 114 showed agglomeration of particles after storage at 54 °C for two weeks. Significant amount of residue on 75 micron sieves was observed.Table 27: Particle size control and wet sieve for selected Formulations with polyethylene (20) sorbitan as the built-in adjuvant.

[0089] As illustrated in microscope images of Fig. 7, Formulation 110 provided good particle size control, while agglomeration of particles was observed in Formulation 109 and 113 after storage at 54 °C for two weeks.

[0090] Selected Formulations were subjected to a spray droplet characterization. The spray solutions of test formulations were prepared by mixing 52.36% weight loading of 240g / L SC with built-in adjuvant as 22.22% pure product or 47.64% EW, 0.06% additional thickener and remaining water. The spray solution was prepared by diluting the formulations to reach a use rate of Tiapyrachlor / ha at 0.416% or 0.031%. Selected test formulations were sprayed through a XR8002 nozzle and an AIXR11004 at 40 PSI. Drift performance results (expressed as % volume of the number of droplets below 150 pm) were displayed in Table 28. Formulations containingbuilt-in Adjuvant 17 and Adjuvant 20 showed a significantly lower % fines < 150 pm compared to water and other built-in adjuvants, such as polyethylene (20) sorbitan, polyethylene (80) sorbitan, and polyether polysiloxane.Table 28: Drift performance of 120g / L SC formulations with built-in DRT.

[0091] All references, including publications, patent applications, and patents, cited herein are hereby incorporated by reference to the same extent as if each reference were individually and specifically indicated to be incorporated by reference and were set forth in its entirety herein.

[0092] Preferred embodiments of this invention are described herein, including the best mode known to the inventors for carrying out the invention. Variations of those preferred embodiments may become apparent to those of ordinary skill in the art upon reading the foregoing description. The inventors expect skilled artisans to employ such variations as appropriate, and the inventors intend for the invention to be practiced otherwise than as specifically described herein. Accordingly, this invention includes all modifications and equivalents of the subject matter recited in the claims appended hereto as permitted by applicable law. Moreover, any combination of the above-described elements in all possible variations thereof is encompassed by the invention unless otherwise indicated herein or otherwise clearly contradicted by context.

Claims

CLAIM(S):

1. A suspension concentrate insecticidal formulation comprising:(a) at least a water-soluble active ingredient, wherein water solubility of the active ingredient is from about 0.3 g / L to about 30 g / L at 25 °C;(b) at least one anionic or nonionic dispersant from about 1 to about 15 weight percent of the insecticidal formulation; and(c) optionally a second anionic or nonionic dispersant, wherein the second dispersant comprises from about 0 to about 10 weight percent of the insecticidal formulation.

2. The suspension concentrate insecticidal formulation of claim 1, wherein the water- soluble active ingredient is Tiapyrachlor.

3. The suspension concentrate insecticidal formulation of claim 1 or 2, comprises the active ingredient from about 1% to about 45% by weight.

4. The suspension concentrate insecticidal formulation of any one of claims 1-3, further comprises a second active ingredient selected from groups comprising sulfoxaflor, triflumezopyrim, acetamiprid, clothianidin, dicloromezotiaz, dinotefuran, fenmezoditiaz, flupyradifurone, flupyrimin, imidacloprid, nitenpyram, nicotine, spinetoram, spinosad, N- (2-fluoro-4-{l-[4-(trifluoromethoxy)phenyl]-12 / -l,2,4-triazol-3-yl}phenyl)-7V-[(2Z)-3-{ 5-methyl-2-[(2, 2, 2-tri fluoroethoxy )methyl]phenyl }-4-oxo- 1, 3-thiazolidin-2- ylidene]urea, thiamethoxam, or combination thereof.

5. The insecticidal formulation of any one of claims 1-4, wherein the ratio of the water- soluble active ingredient to the second active ingredient is from 100: 1 to 1 : 100 by weight.

6. The insecticidal formulation of any one of claims 1-4, wherein the dispersant (b) is selected from groups comprising naphthalene sulfonate condensate, lignosulfonate, acrylate copolymer, polymethylmethacrylate, polymeric phenyl glycidyl ether, polymeric amphoteric dispersant or ethoxylated phosphate ester.

7. The insecticidal formulation of any one of claims 1-5, wherein the dispersant (b) is sodium alkyl naphthalene sulfonate condensate, polymeric phenyl glycidyl ether, or polymeric amphoteric dispersant.

8. The insecticidal formulation of any one of claims 1-7, wherein the second anionic or nonionic dispersant (c) is selected from groups comprising sodium lignosulfonate, Kraft lignosulfonate, polyoxypropylene-polyoxyethylene block copolymer, ethoxylated tristyrylphenols, polymethyl methacrylate-polyethylene glycol graft copolymer, ethylene oxide-styrene oxide copolymer monooctyl ether, polymer with oxirane, mono(3,5,5- trimethylhexyl) ether, EO / PO Block monobutyl ether, polymeric ester, or combinations thereof.

9. The insecticidal formulation of any one of claims 1-8, wherein the insecticidal formulation comprises the dispersant (c) from about 1% to about 8% by weight.

10. The insecticidal formulation of any one of the claims 1-9, wherein the weight ratio of the dispersants (b):(c) is from about 1 :10 to about 10:1.

11. The insecticidal formulation of any one of claims 1-10, wherein insecticidal formulation further comprises an antifreeze agent, an antifoam agent, one or more antimicrobial agents, one or more thickeners, a solvent, or a combination thereof.

12. The insecticidal formulation of any one of claims 1-11, further comprises a built-in adjuvant comprising canola oil, methyl soyate oil, polyethylene (20) sorbitan, white mineral oil, bio-based oil, tris-2(ethylhexyl) phosphate, alcohols ethoxylated propoxylated, or combination thereof.

13. The insecticidal formulation of any one of claims 1-12, comprises the antimicrobial agents from 0.01% to 2.00% by weight.

14. The insecticidal formulation of any one of claims 1-12, comprises the thickeners from 0.1% to 2.0% by weight.

Images