Occlusion apparatus

Abstract

Disclosed in the present invention is an occlusion apparatus, which comprises a first disc body, a second disc body, a waist portion, and a connecting portion, wherein the first disc body and the second disc body are connected by means of the waist portion; the first disc body is configured to be placed on a first side of a site to be occluded; the second disc body is configured to be placed on a second side of said site; the waist portion penetrates through said site; the connecting portion is disposed on a side of the first disc body and / or the second disc body close to said site, and the connecting portion is configured to be fixedly connected to a peripheral tissue of said site. The present invention can achieve precise occlusion of said site, and can enable the first disc body, the second disc body, and the waist portion to adhere well to the wall of the peripheral tissue of said site. Moreover, the occlusion apparatus can be prevented from falling off, and the use of the occlusion apparatus can prevent excessive occlusion, so that obstruction of the blood flow in a collateral vessel at said site can be prevented, thereby avoiding paralysis.

Description

An occlusion device

[0001] Cross-reference to Related Applications

[0002] The present application claims priority to the Chinese patent application No. 202410865846.5, filed on June 28, 2024, and entitled "An occlusion device", the content of which is incorporated herein by reference in its entirety. TECHNICAL FIELD

[0003] The present application belongs to the technical field of medical devices, and particularly relates to an occlusion device. BACKGROUND

[0004] Cardiovascular diseases generally include heart diseases and / or vascular diseases. Common congenital heart diseases include interventricular septal defect, atrial septal defect, patent ductus arteriosus, patent foramen ovale and the like. In vascular diseases, aortic dissection rupture refers to the blood in the aortic lumen entering the middle layer of the aortic wall through the aortic intimal break to form a dissection, which is usually caused by high blood pressure, vascular intimal lesions tearing or pregnancy trauma, traffic accident injury. Aortic dissection rupture has a high mortality rate and is one of the extremely dangerous emergency diseases in surgery. If not treated in time, the mortality rate within 48 hours after onset can reach 55%, and it has become the second cause of death in traffic accidents after craniocerebral trauma.

[0005] However, for congenital heart defect diseases, the current treatment is usually through minimally invasive surgery, but due to the poor fit of the device and the tissue, a large number of patients still have shunt phenomenon after surgery. And the minimally invasive surgery for aortic dissection rupture treatment is extremely limited, and most of the minimally invasive surgeries choose to cover the stent to completely occlude all breaks, but due to the fact that the entire aorta is surrounded by many collateral blood vessels, excessive occlusion will cause collateral blood vessels to be blocked, thereby causing the risk of paralysis. And the surrounding tissue of the aortic dissection break is extremely irregular, and ordinary congenital heart occlusion devices are difficult to fit, thereby causing the risk of falling off and re-leakage. SUMMARY

[0006] The present application aims at the deficiencies of the prior art, and provides an occlusion device.

[0007] To solve the above technical problems, the application adopts the following technical scheme: a plugging device, comprising a first disc body, a second disc body, a waist part and a connecting part; wherein the first disc body and the second disc body are connected through the waist part; the first disc body is used for being placed on a first side of a part to be plugged; the second disc body is used for being placed on a second side of the part to be plugged; the waist part penetrates through the part to be plugged; the connecting part is arranged on a side of the first disc body and / or the second disc body close to the part to be plugged, and is used for being fixedly connected with peripheral tissues of the part to be plugged.

[0008] Further, the first disc body comprises a first framework and a first flow resistance body arranged in the first framework in a circumferential direction, the first flow resistance body being used for resisting blood flow; the second disc body comprises a second framework and a second flow resistance body arranged in the second framework in a circumferential direction, the second flow resistance body being used for resisting blood flow; the first framework, the second framework and the waist part are all in a mesh structure; the connecting part comprises a first connecting part, a second connecting part and / or a third connecting part and a fourth connecting part; the first connecting part is arranged on a side of the first disc body facing the second disc body in a circumferential direction, or is arranged on a side of the second disc body facing the first disc body in a circumferential direction; the second connecting part is arranged on a side of the second disc body facing the first disc body in a circumferential direction, or is arranged on a side of the first disc body facing the second disc body in a circumferential direction; the first connecting part and the second connecting part are both used for fixedly connecting peripheral tissues of the part to be plugged; the third connecting part is arranged on a side of the first disc body facing the second disc body in a circumferential direction, or is arranged on a side of the second disc body facing the first disc body in a circumferential direction; the fourth connecting part is arranged on a side of the second disc body facing the first disc body in a circumferential direction, or is arranged on a side of the first disc body facing the second disc body in a circumferential direction; the third connecting part and the fourth connecting part are used in cooperation for fixedly connecting peripheral tissues of the part to be plugged.

[0009] Further, circumferential edges of the first framework and the first flow resistance body are all inwardly rolled to form a first overlapped edge, circumferential edges of the second framework and the second flow resistance body are all inwardly rolled to form a second overlapped edge, and the first overlapped edge and the second overlapped edge are arranged in opposition.

[0010] Further, when the connecting part comprises the first connecting part, the first connecting part is circumferentially arranged on the first folded edge close to one side of the second folded edge, or circumferentially arranged on the second folded edge close to one side of the first folded edge; when the connecting part comprises the second connecting part, the second connecting part is circumferentially arranged on the second folded edge close to one side of the first folded edge, or circumferentially arranged on the first folded edge close to one side of the second folded edge; when the connecting part comprises the first connecting part and the second connecting part, the first connecting part is circumferentially arranged on the first folded edge close to one side of the second folded edge, and the second connecting part is circumferentially arranged on the second folded edge close to one side of the first folded edge; or the first connecting part is circumferentially arranged on the second folded edge close to one side of the first folded edge, and the second connecting part is circumferentially arranged on the first folded edge close to one side of the second folded edge; the first connecting part and the second connecting part are oppositely and staggered arranged.

[0011] Further, the first connecting part comprises one or more circles of first barbs, and the second connecting part comprises one or more circles of second barbs.

[0012] Further, when the first barbs are multiple circles, the multiple circles of the first barbs are radially spaced, each circle of the first barbs comprises multiple first barbs circumferentially spaced, and when the second barbs are multiple circles, the multiple circles of the second barbs are radially spaced, each circle of the second barbs comprises multiple second barbs circumferentially spaced.

[0013] Further, the first barb and the second barb each comprise a first fixed end, a first connecting body, and a first hook part, the first fixed end connects the first hook part through the first connecting body, the first hook part is arranged outside the first skeleton and / or the second skeleton for fixing and connecting the peripheral tissue of the to-be-plugged part, the first fixed end of the first barb is fixedly connected with the first skeleton or the first flow-blocking body, or the first fixed end of the first barb is fixedly connected with the second skeleton or the second flow-blocking body, the first fixed end of the second barb is fixedly connected with the second skeleton or the second flow-blocking body, or the first fixed end of the second barb is fixedly connected with the first skeleton or the first flow-blocking body.

[0014] Further, the first fixed end of the first barb and the first fixed end of the second barb are both flexible planar structures.

[0015] Further, the first fixed end of the first barb is adhered to the first skeleton or the first flow resistance body by hot pressing, or the first fixed end of the first barb is adhered to the second skeleton or the second flow resistance body by hot pressing; the first fixed end of the second barb is adhered to the second skeleton or the second flow resistance body by hot pressing, or the first fixed end of the second barb is adhered to the first skeleton or the first flow resistance body by hot pressing.

[0016] Further, the first connector of the first barb and / or the first connector of the second barb is a first elastic body.

[0017] Further, when the connecting part includes the third connecting part and the fourth connecting part, the third connecting part is circumferentially arranged on one side of the first folded edge close to the second folded edge, and the fourth connecting part is circumferentially arranged on one side of the second folded edge close to the first folded edge; or the third connecting part is circumferentially arranged on one side of the second folded edge close to the first folded edge, and the fourth connecting part is circumferentially arranged on one side of the first folded edge close to the second folded edge; the third connecting part and the fourth connecting part are oppositely arranged and used in cooperation.

[0018] Further, the third connecting part includes one or more rings, and the fourth connecting part includes one or more third barbs, and the third barbs are used in cooperation with the rings.

[0019] Further, when the rings are multiple, the multiple rings are radially spaced, each ring includes multiple rings arranged circumferentially at intervals, and when the third barbs are multiple, the multiple third barbs are radially spaced, each third barb includes multiple third barbs arranged circumferentially at intervals.

[0020] Further, the ring includes a second fixed end, a second connector, and a ring body, the second fixed end connects the ring body through the second connector, the ring body is arranged outside the first skeleton or the second skeleton, the second fixed end is fixedly connected with the first skeleton or the first flow resistance body, or the second fixed end is fixedly connected with the second skeleton or the second flow resistance body.

[0021] Further, the third barb comprises a third fixed end, a third connecting body, a pointed end and a second hooking part, the third fixed end is connected with the pointed end through the third connecting body, the pointed end is used for penetrating the peripheral tissue of the part to be blocked and the ring body, the second hooking part is arranged on the third connecting body close to the pointed end and is used for clamping on the ring body, and the third fixed end is fixedly connected with the second framework or the second flow blocking body, or the third fixed end is fixedly connected with the first framework or the first flow blocking body.

[0022] Further, the second fixed end and the third fixed end are flexible plane structures.

[0023] Further, the second fixed end is adhered on the first framework or the first flow blocking body through hot pressing, and the third fixed end is adhered on the second framework or the second flow blocking body through hot pressing; or the third fixed end is adhered on the first framework or the first flow blocking body through hot pressing, and the second fixed end is adhered on the second framework or the second flow blocking body through hot pressing.

[0024] Further, the second connecting body and / or the third connecting body are second elastic bodies.

[0025] Further, the intercept of the first overlapping edge on the first framework is smaller than that of the rest of the first framework, the intercept of the second overlapping edge on the second framework is smaller than that of the rest of the second framework, and the intercept of the waist part is smaller than that of the rest of the first framework except the first overlapping edge and / or that of the rest of the second framework except the second overlapping edge.

[0026] Further, the height of the first overlapping edge is greater than or equal to 6 times the diameter of the wire, and the height of the second overlapping edge is greater than or equal to 6 times the diameter of the wire.

[0027] Further, the inside of the waist part is provided with a third flow blocking body for blocking blood flow.

[0028] Further, the middle part of the first disc body is provided with a first protruding part, the first protruding part protrudes away from the second disc body, the middle part of the second disc body is provided with a second protruding part, and the second protruding part protrudes away from the first disc body.

[0029] Further, the inside of the first protruding part is provided with a first inner concave surface, the inside of the second protruding part is provided with a second inner concave surface, and the first inner concave surface and the second inner concave surface are oppositely arranged.

[0030] Further, the middle part of the second framework is provided with a connecting rivet head.

[0031] Further, the first disc body, the second disc body and the waist are made of elastic material and / or memory material.

[0032] Further, the first disc body, the second disc body and the waist are made of degradable material.

[0033] Further, the to-be-plugged site includes aortic dissection break, atrial septal defect, patent foramen ovale defect, ventricular septal defect and / or patent ductus arteriosus defect.

[0034] Compared with the prior art, the present application has the following advantages:

[0035] 1. The plugging device of the present application is provided with a first disc body, a second disc body, a waist and a connecting part, the first disc body is arranged on the first side of the to-be-plugged site, the second disc body is arranged on the second side of the to-be-plugged site, and the connecting part is used to fixedly connect the peripheral tissue of the to-be-plugged site, so that the plugging device can accurately plug the to-be-plugged site, and the first disc body, the second disc body and the waist can well fit the peripheral tissue wall of the to-be-plugged site, while preventing the plugging device from falling off, and over-plugging can be prevented by using the plugging device, so as to prevent the blood flow of the collateral vessels of the to-be-plugged site from being blocked, and paralysis is avoided.

[0036] 2. The plugging device of the present application is provided with a first overlapping edge and a second overlapping edge, which can increase the contact area and clamping force of the plugging device and the peripheral tissue of the to-be-plugged site.

[0037] 3. The first connecting part of the plugging device of the present application includes one or more first barbs, and the second connecting part includes one or more second barbs, which can further facilitate the connection of the plugging device and the peripheral tissue of the to-be-plugged site, and has good stability and reliability.

[0038] 4. The first fixed end of the first barb, the first fixed end of the second barb, the second fixed end and the third fixed end of the plugging device of the present application are all flexible plane structures, which can increase the contact area, further improve the stability and reliability of the first barb, the second barb and the third barb and the corresponding skeleton and / or flow blocking body connected by the lock ring, and can meet the actual needs.

[0039] 5. The first connecting body of the first barb, the first connecting body of the second barb, the second connecting body and / or the third connecting body of the plugging device of the present application are the second elastic body, which can slow down the pulling force of the first barb, the second barb and the second hook part and the lock ring on the peripheral tissue of the to-be-plugged site, so as to better protect the peripheral tissue of the to-be-plugged site and prevent it from being damaged.

[0040] 6. In the sealing device of the present invention, the intercept of the first overlapping edge on the first frame is smaller than the intercept of the rest of the first frame, the intercept of the second overlapping edge on the second frame is smaller than the intercept of the rest of the second frame, and the intercept of the waist is smaller than the intercept of the rest of the first frame excluding the first overlapping edge and / or smaller than the intercept of the rest of the second frame excluding the second overlapping edge. This can improve the rigidity of the first overlapping edge, the second overlapping edge, and the waist, thereby effectively increasing the support force of the first frame, the second frame, and the waist, and improving the ability of the first frame, the second frame, and the waist to adapt to different tissues.

[0041] 7. The sealing device of the present invention has a first protrusion on the first disc body and a second protrusion on the second disc body, which facilitates the formation of clamping force and prevents the first and second disc bodies from collapsing and prevents the edges from curling up.

[0042] 8. The sealing device of the present invention has a first concave surface inside the first protrusion and a second concave surface inside the second protrusion. The first concave surface and the second concave surface are arranged opposite to each other, which can effectively enhance the radial support force of the sealing device.

[0043] 9. The first disc, the second disc, and the waist of the sealing device of the present invention are all made of elastic material and / or shape memory material, which can be easily compressed and / or recover from deformation, and are convenient to use.

[0044] 10. The first disc, the second disc, and the waist of the sealing device of the present invention are all made of biodegradable materials, which can effectively realize the biodegradation of the sealing device. Attached Figure Description

[0045] Figure 1 shows a cross-sectional schematic diagram of a specific embodiment of the sealing device of the present invention;

[0046] Figure 2 shows a cross-sectional schematic diagram of another specific embodiment of the sealing device of the present invention;

[0047] Figure 3 shows a schematic diagram of the mesh structure of a specific embodiment of the sealing device of the present invention, including the first frame, second fastener, waist, first overlapping edge, and second overlapping edge.

[0048] Figure 4 shows a schematic diagram of a specific embodiment of the sealing device of the present invention, in which the first connecting part is fixedly connected to the first blocking fluid and the second connecting part is fixedly connected to the second blocking fluid.

[0049] Figure 5 shows a top view of a specific embodiment of the sealing device of the present invention, in which the first barb and / or the second barb are fixedly connected to the first or second fluid barrier.

[0050] Figure 6 shows a side view of one embodiment of the first barb and / or the second barb of the occlusion device of the present application fixedly connected to the first flow resistor or the second flow resistor;

[0051] Figure 7 shows a top view of another embodiment of the first barb and / or the second barb of the occlusion device of the present application fixedly connected to the first flow resistor or the second flow resistor;

[0052] Figure 8 shows a side view of another embodiment of the first barb and / or the second barb of the occlusion device of the present application fixedly connected to the first flow resistor or the second flow resistor;

[0053] Figure 9 shows a structural view of one embodiment of the first barb or the second barb of the occlusion device of the present application;

[0054] Figure 10 shows a structural view of another embodiment of the first barb or the second barb of the occlusion device of the present application;

[0055] Figure 11 shows a structural view of one embodiment of the third barb of the occlusion device of the present application used in cooperation with the locking ring;

[0056] Figure 12 shows a structural view of one embodiment of the occlusion device of the present application packed in the break by the waist;

[0057] Figure 13 shows a structural view of one embodiment of the first barb and the second barb of the occlusion device of the present application hooked on the peripheral tissue of the aortic dissection break;

[0058] Figure 14 shows a structural view of one embodiment of the third barb of the occlusion device of the present application locked together with the locking ring by penetrating the peripheral tissue of the aortic dissection break;

[0059] Figure 15 shows a structural view of one embodiment of the formation of the atrial septal defect and / or the ventricular septal defect on the heart;

[0060] Figure 16 shows a structural view of one embodiment of the formation of the patent foramen ovale defect and / or the ventricular septal defect on the heart;

[0061] Figure 17 shows a structural view of one embodiment of the occlusion device of the present application occluding the atrial septal defect;

[0062] Figure 18 shows a structural view of one embodiment of the occlusion device of the present application occluding the patent foramen ovale defect;

[0063] Figure 19 shows a structural view of one embodiment of the occlusion device of the present application occluding the ventricular septal defect.

[0064] Wherein, A is the part to be occluded; A1 is the aortic dissection rupture; A2 is the atrial septal defect; A3 is the patent foramen ovale defect; A4 is the ventricular septal defect; B is the peripheral tissue; 10 is the first disc body; 101 is the first skeleton; 102 is the first flow resistance body; 103 is the first protruding part; 104 is the first inner concave surface; 20 is the second disc body; 201 is the second skeleton; 202 is the second flow resistance body; 203 is the second protruding part; 204 is the second inner concave surface; 30 is the waist part; 40 is the first connecting part; 401 is the first barb; 50 is the second connecting part; 501 is the second barb; 60 is the third connecting part; 601 is the second fixed end; 602 is the second connecting body; 603 is the ring body; 70 is the fourth connecting part; 701 is the third fixed end; 702 is the third connecting body; 703 is the pointed end part; 704 is the second hook part; 90 is the first overlapping edge; 100 is the second overlapping edge; 110 is the first fixed end; 120 is the first connecting body; 130 is the first hook part; 140 is the third flow resistance body; 150 is the connecting rivet head; 160 is the true lumen; 170 is the false lumen; 180 is the right atrium; 190 is the left atrium; 200 is the right ventricle; 210 is the left ventricle; 220 is the atrial septum; 230 is the ventricular septum. DETAILED DESCRIPTION

[0065] The application will be further described below with reference to the embodiments shown in the drawings.

[0066] The directional terms mentioned in the application, such as "inner", "outer", "circumferential", "axial", etc., are only the way of reference to the drawings. Therefore, the directional terms used are used to illustrate and understand the application, and not to limit the application.

[0067] As shown in FIGS. 1-3, the occlusion device of the application comprises a first disc body 10, a second disc body 20, a waist part 30 and a connecting part. Wherein,

[0068] The first disc body 10 and the second disc body 20 are connected through the waist part 30.

[0069] The first disc body 10 is used to be placed on the first side of the part A to be occluded.

[0070] The second disc body 20 is used to be placed on the second side of the part A to be occluded. The second side of the part A to be occluded is oppositely arranged with the first side of the part A to be occluded.

[0071] The waist part 30 penetrates the part A to be occluded.

[0072] The side of the first disc body 10 and / or the second disc body 20 close to the part A to be occluded is provided with the connecting part, and the connecting part is used to be fixedly connected with the peripheral tissue B of the part A to be occluded.

[0073] The first disc body 10 is arranged on the first side of the to-be-plugged part A, the second disc body 20 is arranged on the second side of the to-be-plugged part A, and the peripheral tissue B of the to-be-plugged part A is fixedly connected by the connecting part, so that the plugging device can accurately plug the to-be-plugged part A, and the first disc body 10, the second disc body 20 and the waist part 30 can well fit on the peripheral tissue wall of the to-be-plugged part A, while preventing the plugging device from falling off, and over-plugging can be prevented by using the plugging device, so as to prevent the blood flow of the to-be-plugged part side branch blood vessel from being blocked, and paralysis is avoided.

[0074] In one specific embodiment, the first disc body 10 comprises a disc-shaped first framework 101 and a first flow-blocking body 102 arranged in the first framework 101 in a circumferential direction. The first flow-blocking body 102 is used to block blood flow.

[0075] The second disc body 20 comprises a disc-shaped second framework 201 and a second flow-blocking body 202 arranged in the second framework 201 in a circumferential direction. The second flow-blocking body 202 is used to block blood flow.

[0076] The first framework 101, the second framework 201 and the waist part 30 are all in a mesh structure. The first framework 101 and the second framework 201 are connected through the waist part 30.

[0077] The connecting part comprises a first connecting part 40, a second connecting part 50 and / or a third connecting part 60 and a fourth connecting part 70.

[0078] The first connecting part 40 is arranged on one side of the first disc body 10 facing the second disc body 20 in a circumferential direction, or is arranged on one side of the second disc body 20 facing the first disc body 10 in a circumferential direction.

[0079] The second connecting part 50 is arranged on one side of the second disc body 20 facing the first disc body 10 in a circumferential direction, or is arranged on one side of the first disc body 10 facing the second disc body 20 in a circumferential direction.

[0080] The first connecting part 40 and the second connecting part 50 are both used to fixedly connect the peripheral tissue B of the to-be-plugged part A.

[0081] The third connecting part 60 is arranged on one side of the first disc body 10 facing the second disc body 20 in a circumferential direction, or is arranged on one side of the second disc body 20 facing the first disc body 10 in a circumferential direction.

[0082] The fourth connecting part 70 is arranged on one side of the second disc body 20 facing the first disc body 10 in a circumferential direction, or is arranged on one side of the first disc body 10 facing the second disc body 20 in a circumferential direction.

[0083] The third connecting part 60 and the fourth connecting part 70 are used in cooperation to fixedly connect the peripheral tissue B of the to-be-plugged part A.

[0084] The peripheral tissue B of the to-be-plugged site A is connected by the connecting part, so that the plugging device can accurately plug the to-be-plugged site A, the first disc body 10, the second disc body 20 and the waist part 30 can well adhere to the peripheral tissue wall of the to-be-plugged site A, and the plugging device can be prevented from falling off, thereby preventing the to-be-plugged site A from leaking again. The plugging device can also prevent excessive plugging, thereby preventing the blood flow of the collateral blood vessels from being blocked and avoiding paralysis.

[0085] In a specific embodiment, as shown in FIGS. 1, 2, 4 and 13, the circumferential edges of the first skeleton 101 and the first flow-blocking body 102 are both inwardly rolled to form a first folded edge 90. The circumferential edges of the second skeleton 201 and the second flow-blocking body 202 are both inwardly rolled to form a second folded edge 100. The first folded edge 90 and the second folded edge 100 are oppositely arranged. The first folded edge 90 and / or the second folded edge 100 can increase the contact area and clamping force of the plugging device adhering to the peripheral tissue B of the to-be-plugged site A.

[0086] In a specific embodiment, as shown in FIGS. 1, 2, 4 and 13, when the connecting part includes the first connecting part 40, the first connecting part 40 is circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100, or circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90.

[0087] When the connecting part includes the second connecting part 50, the second connecting part 50 is circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90, or circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100.

[0088] When the connecting part includes the first connecting part 40 and the second connecting part 50, the first connecting part 40 is circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100, and the second connecting part 50 is circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90; or the first connecting part 40 is circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90, and the second connecting part 50 is circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100. The first connecting part 40 and the second connecting part 50 are oppositely and staggered arranged.

[0089] The first connecting part 40 and / or the second connecting part 50 can facilitate connecting the peripheral tissue B of the to-be-plugged site A, accurately plugging the to-be-plugged site A, and well adhering to the peripheral tissue wall of the to-be-plugged site A, thereby preventing the plugging device from falling off.

[0090] In a specific embodiment, as shown in FIGS. 5-8, the first connecting portion 40 comprises one or more first barbs 401. The second connecting portion 50 comprises one or more second barbs 501. The one or more first barbs 401 and / or the one or more second barbs 501 can further facilitate the connection of the occlusion device to the peripheral tissue B of the occlusion site A, and the stability and reliability are good.

[0091] In a specific embodiment, as shown in FIGS. 7 and 8, when the first barbs 401 are in multiple loops, the multiple loops of the first barbs 401 are arranged radially spaced apart, and each loop of the first barbs 401 comprises a plurality of first barbs 401 arranged circumferentially spaced apart. When the second barbs 501 are in multiple loops, the multiple loops of the second barbs 501 are arranged radially spaced apart, and each loop of the second barbs 501 comprises a plurality of second barbs 501 arranged circumferentially spaced apart. The multiple loops of the first barbs 401 and / or the multiple loops of the second barbs 501 can further improve the stability and reliability of the occlusion device in connecting the peripheral tissue B of the occlusion site A.

[0092] In a specific embodiment, as shown in FIGS. 4-10 and FIG. 13, the first barbs 401 and the second barbs 501 each comprise a first fixed end 110, a first connecting body 120, and a first hook portion 130. The first fixed end 110 connects the first hook portion 130 through the first connecting body 120. The first hook portion 130 is arranged outside the first framework 101 and / or the second framework 201 for fixedly connecting the peripheral tissue B of the occlusion site A. The first fixed end 110 of the first barbs 401 is fixedly connected with the first framework 101 or the first flow-blocking body 102, or the first fixed end 110 of the first barbs 401 is fixedly connected with the second framework 201 or the second flow-blocking body 202. The first fixed end 110 of the second barbs 501 is fixedly connected with the second framework 201 or the second flow-blocking body 202, or the first fixed end 110 of the second barbs 501 is fixedly connected with the first framework 101 or the first flow-blocking body 102. The first fixed end 110 can improve the stability and reliability of the first barbs 401 and / or the second barbs 501 in connecting the corresponding framework and / or flow-blocking body, and the structure is simple and convenient to use. Moreover, since the first hook portion 130 has a relatively sharp hook, it is convenient to pass through the peripheral tissue B of the occlusion site A and to hook the first hook portion 130 on the peripheral tissue B of the occlusion site A, and the stability and reliability are good.

[0093] In a specific embodiment, as shown in FIGS. 4-10 and FIG. 13, the first fixed end 110 of the first barbs 401 and the first fixed end 110 of the second barbs 501 are both flexible planar structures, which can increase the contact area, further improve the stability and reliability of the first barbs 401 and / or the second barbs 501 in connecting the corresponding framework and / or flow-blocking body, and can meet the actual needs.

[0094] In a specific embodiment, as shown in FIGS. 4-8, as shown in FIG. 13, the first fixed end 110 of the first barb 401 is heat-pressed and adhered to the first skeleton 101 or the first resistance body 102, or the first fixed end 110 of the first barb 401 is heat-pressed and adhered to the second skeleton 201 or the second resistance body 202, which is stable, reliable, and convenient and efficient. The first fixed end 110 of the second barb 501 is heat-pressed and adhered to the second skeleton 201 or the second resistance body 202, or the first fixed end 110 of the second barb 501 is heat-pressed and adhered to the first skeleton 101 or the first resistance body 102, which is stable, reliable, and convenient and efficient. When the first fixed end 110 of the first barb 401 is connected to the first resistance body 102 or the second resistance body 202, the first connecting body 120 needs to pass through the first skeleton 101 or the second skeleton 201, which is simple in structure and convenient to use.

[0095] In a specific embodiment, as shown in FIG. 10, the first connecting body 120 of the first barb 401 and / or the first connecting body 120 of the second barb 501 is a first elastic body. When the first barb 401 and / or the second barb 501 are hooked on the peripheral tissue B of the occlusion site A, the first elastic body can slow down the pulling force of the first hooking part 130 on the peripheral tissue B of the occlusion site A, thereby better protecting the peripheral tissue B of the occlusion site A and preventing it from being damaged.

[0096] In a specific embodiment, as shown in FIG. 10, the first elastic body is a spring, which is simple in structure and convenient to use.

[0097] In a specific embodiment, as shown in FIGS. 1, 11, and 14, when the connecting part includes a third connecting part 60 and a fourth connecting part 70, the third connecting part 60 is circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100, and the fourth connecting part 70 is circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90; or the third connecting part 60 is circumferentially arranged on one side of the second folded edge 100 close to the first folded edge 90, and the fourth connecting part 70 is circumferentially arranged on one side of the first folded edge 90 close to the second folded edge 100. The third connecting part 60 and the fourth connecting part 70 are oppositely arranged and used in cooperation. The third connecting part 60 and the fourth connecting part 70 can improve the stability and reliability of the occlusion device in connecting the peripheral tissue B of the occlusion site A, and are simple in structure and convenient to use.

[0098] In a specific embodiment, the third connecting part 60 comprises one or more loops, and the fourth connecting part 70 comprises one or more third barbs, and the third barbs are used in cooperation with the loops. By using the third barbs in cooperation with the loops, the stability and reliability of the occlusion device in connecting the peripheral tissue B of the occlusion site A can be improved, and the process is convenient and efficient.

[0099] In a specific embodiment, when the loops are multiple loops, the multiple loops are arranged radially at intervals, and each loop comprises multiple loops arranged circumferentially at intervals. When the third barbs are multiple third barbs, the multiple third barbs are arranged radially at intervals, and each third barb comprises multiple third barbs arranged circumferentially at intervals. By using the multiple loops and the multiple third barbs, the stability and reliability of the occlusion device in connecting the peripheral tissue B of the occlusion site A can be further improved.

[0100] In a specific embodiment, as shown in FIGS. 11 and 14, the loop comprises a second fixed end 601, a second connecting body 602, and a ring body 603. The second fixed end 601 is connected to the ring body 603 through the second connecting body 602, and the ring body 603 is arranged outside the first framework 101 or the second framework 102. The second fixed end 601 is fixedly connected to the first framework 101 or the first blocking body 102, or the second fixed end 601 is fixedly connected to the second framework 201 or the second blocking body 202. When the second fixed end 601 is connected to the first blocking body 102 or the second blocking body 202, the second connecting body 602 needs to pass through the first framework 101 or the second framework 201, which is simple in structure and convenient to use.

[0101] In a specific embodiment, as shown in FIGS. 11 and 14, the third barb comprises a third fixed end 701, a third connecting body 702, a pointed end 703, and a second hook portion 704. The third fixed end 701 is connected to the pointed end 703 through the third connecting body 702, and the pointed end 703 is used to pass through the peripheral tissue B of the occlusion site A and the ring body 603. The second hook portion 704 is arranged on the third connecting body 702 at a position close to the pointed end 703 and is used to be clamped on the ring body 603. The third fixed end 701 is fixedly connected to the second framework 201 or the second blocking body 202, or the third fixed end 701 is fixedly connected to the first framework 101 or the first blocking body 102. By using the pointed end 703 to pass through the peripheral tissue B of the occlusion site A and the ring body 603, and using the second hook portion 704 to be clamped on the ring body 603, the third barb and the loop can be locked together, so as to ensure that the first disc body 10 and the second disc body 20 are locked and tightened, which is convenient and efficient, and has good stability and reliability.

[0102] In a specific embodiment, as shown in FIG. 11 and FIG. 14, the second fixed end 601 and the third fixed end 701 are both flexible flat structures, which can increase the contact area, further improve the stability and reliability of the locking ring and / or the third barb connecting the corresponding framework and / or the flow blocking body, and can meet the actual needs.

[0103] In a specific embodiment, the second fixed end 601 is bonded on the first framework 101 or the first flow blocking body 102 by hot pressing, and the third fixed end 701 is bonded on the second framework 201 or the second flow blocking body 202 by hot pressing; or the third fixed end 701 is bonded on the first framework 101 or the first flow blocking body 102 by hot pressing, and the second fixed end 601 is bonded on the second framework 201 or the second flow blocking body 202 by hot pressing, which has good stability, good reliability, and is convenient and efficient.

[0104] In a specific embodiment, the second connecting body 602 and / or the third connecting body 702 is a second elastic body, which can slow down the pulling force of the second hook portion 704 and the ring body 603 on the peripheral tissue B of the to-be-plugged site A when the tip portion 703 of the third barb penetrates through the peripheral tissue B of the to-be-plugged site A and the second hook portion 704 is clamped on the ring body 603, thereby better protecting the peripheral tissue B of the to-be-plugged site A and preventing it from being damaged.

[0105] In a specific embodiment, as shown in FIG. 3, the intercept of the first folded edge 90 on the first framework 101 is smaller than the intercept of the rest of the first framework 101, which can improve the hardness of the first folded edge 90, thereby effectively increasing the supporting force of the first framework 101 and improving the ability of the first framework 101 to adapt to different tissues.

[0106] In a specific embodiment, as shown in FIG. 3, the intercept of the second folded edge 100 on the second framework 201 is smaller than the intercept of the rest of the second framework 201, which can improve the hardness of the second folded edge 100, thereby effectively increasing the supporting force of the second framework 201 and improving the ability of the second framework 201 to adapt to different tissues.

[0107] In a specific embodiment, as shown in FIG. 3, the intercept of the waist portion 30 is smaller than the intercept of the rest of the first framework 101 except the first folded edge 90 and / or the intercept of the rest of the second framework 201 except the second folded edge 100, which can improve the hardness of the waist portion 30, thereby effectively increasing the supporting force of the waist portion 30 and improving the ability of the plugging device to adapt to different tissues.

[0108] In a specific embodiment, as shown in FIG. 2, the height H1 of the first overlapping edge 90 is greater than or equal to 6 times the wire diameter, which can further improve the hardness of the first overlapping edge 90 and further improve the ability of the first skeleton 101 to adapt to different tissues.

[0109] In a specific embodiment, as shown in FIG. 2, the height H2 of the second overlapping edge 100 is greater than or equal to 6 times the wire diameter, which can further improve the hardness of the second overlapping edge 100 and further improve the ability of the second skeleton 201 to adapt to different tissues.

[0110] In a specific embodiment, as shown in FIG. 1 and FIG. 2, the inside of the waist portion 30 is circumferentially provided with a third blocking body 140 for blocking blood, which can effectively prevent the blood on the first skeleton 101 side of the peripheral tissue B of the occlusion site A from flowing to the second skeleton 201 side, and / or effectively prevent the blood on the second skeleton 201 side of the peripheral tissue B of the occlusion site A from flowing to the first skeleton 101 side.

[0111] In a specific embodiment, as shown in FIG. 1 and FIG. 2, the middle portion of the first disc body 10 is provided with a first protruding portion 103, which protrudes away from the second disc body 20, which can facilitate the formation of clamping force and prevent the first disc body 10 from collapsing and prevent the edge position from being warped.

[0112] In a specific embodiment, as shown in FIG. 1 and FIG. 2, the middle portion of the second disc body 20 is provided with a second protruding portion 203, which protrudes away from the first disc body 10, which can facilitate the formation of clamping force and prevent the first disc body 10 from collapsing and prevent the edge position from being warped.

[0113] In a specific embodiment, as shown in FIG. 1 and FIG. 2, the inside of the first protruding portion 103 is provided with a first inner concave surface 104, and the inside of the second protruding portion 203 is provided with a second inner concave surface 204, and the first inner concave surface 104 and the second inner concave surface 204 are oppositely arranged. The first inner concave surface 104 and the second inner concave surface 204 can effectively enhance the radial support force of the occlusion device.

[0114] In a specific embodiment, as shown in FIG. 1 and FIG. 2, the middle portion of the second skeleton 201 is provided with a connecting rivet head 150, which can be used to connect the delivery device.

[0115] In a specific embodiment, as shown in FIG. 1, FIG. 2 and FIG. 12, the first disc body 10, the second disc body 20 and the waist portion 30 are all made of elastic material and / or memory material, which can facilitate compression and / or recovery of deformation and is convenient to use.

[0116] In a specific embodiment, as shown in FIG. 1, FIG. 2, and FIG. 12, the first disc body 10, the second disc body 20, and the waist portion 30 are all made of degradable materials, including degradable high molecular materials (such as polylactic acid, poly-p-dioxanone, and / or polycaprolactone) and / or degradable metal materials (such as degradable magnesium-based, zinc-based, and / or iron-based materials) to achieve the biodegradation of the first disc body 10, the second disc body 20, and the waist portion 30.

[0117] When the present application is used, it can occlude the aortic dissection rupture A1, occlude the atrial septal defect A2, occlude the patent foramen ovale defect A3, and / or occlude the ventricular septal defect A4. Among them,

[0118] The aortic dissection includes a true lumen 160 and a false lumen 170, and the circumferential connection of the true lumen 160 and the false lumen 170 forms the aortic dissection rupture A1. The occlusion device is filled on the aortic dissection rupture A1 through the waist portion 30 (as shown in FIG. 12), and the first disc body 10 and the second disc body 20 are arranged in the true lumen 160 and the false lumen 170, respectively (the first disc body 10 and the second disc body 20 can also be arranged in the false lumen 170 and the true lumen 160, respectively). Since the occlusion device has a clamping force on the peripheral tissue B of the aortic dissection rupture A1, the first barb 401 and / or the second barb 501 are used to pierce and hook on the peripheral tissue B of the aortic dissection rupture A1, and / or the sharp end portion 703 is used to pass through the peripheral tissue B of the aortic dissection rupture A1 and the ring body 603, and the second hook portion 704 is used to be clamped on the ring body 603 to achieve locking, which can achieve precise occlusion effect, and can make the first disc body 10, the second disc body 20, and the waist portion 30 well fit on the peripheral tissue wall of the aortic dissection rupture A1, while preventing the occlusion device from falling, and using the occlusion device can prevent excessive occlusion, thereby preventing the blood flow of the collateral vessels of the aortic dissection from being blocked, and avoiding paralysis.

[0119] The structure of the heart includes right atrium 180, left atrium 190, right ventricle 200 and left ventricle 210. The interatrial septum 220 is formed between the left atrium 190 and the right atrium 180, and the interventricular septum 230 is formed between the left ventricle 210 and the right ventricle 200. The interatrial septum 220 has an interatrial septal defect A2 in the middle, the fossa ovalis of the interatrial septum 220 has an oval foramen patent defect A3 in the middle, and the interventricular septum 230 has an interventricular septal defect A4 in the middle (as shown in FIGS. 15 and 16). As shown in FIGS. 17-19, during implantation, the first disc 10 and the second disc 20 of the occlusion device are clamped on both sides of the interatrial septum 220 and / or the interventricular septum 230. Since the occlusion device has clamping force on the peripheral tissue B of the interatrial septal defect A2, the oval foramen patent defect A3 and / or the interventricular septal defect A4, the first barb 401 and / or the second barb 501 are used to pierce and hook on the peripheral tissue B of the interatrial septal defect A2, the oval foramen patent defect A3 and / or the interventricular septal defect A4, and / or the sharp end 703 is used to pass through the peripheral tissue B of the interatrial septal defect A2, the oval foramen patent defect A3 and / or the interventricular septal defect A4 and the ring 603, and the second hook portion 704 is used to be clamped on the ring 603 to achieve locking, so that the disc surface of the first disc 10 and the disc surface of the second disc 20 are more firmly attached to the tissue wall, and at the same time, they will not fall off, achieving the occlusion of the occlusion device to the interatrial septal defect A2, the oval foramen patent defect A3 and / or the interventricular septal defect A4. And the occlusion device can prevent excessive occlusion, thereby preventing the blood flow of the collateral vessels of the heart from being blocked and avoiding paralysis.

[0120] The scope of protection of the present application is not limited to the above-mentioned embodiments. Obviously, those skilled in the art can make various modifications and variations to the present application without departing from the scope and spirit of the present application. If these modifications and variations belong to the scope of the claims of the present application and their equivalent technologies, the intention of the present application also includes these modifications and variations.

Claims

1. A sealing device, characterized in that, include: The first disc body (10), the second disc body (20), the waist section (30), and the connecting section; wherein, The first disc body (10) and the second disc body (20) are connected by the waist section (30); The first disc (10) is used to be placed on the first side of the part to be sealed (A); The second disc (20) is used to be placed on the second side of the part (A) to be sealed; The waist section (30) penetrates the part (A) to be sealed; The connecting portion is provided on the side of the first disc (10) and / or the second disc (20) near the part to be sealed (A), and the connecting portion is used to be fixedly connected to the surrounding tissue (B) of the part to be sealed (A).

2. The sealing device according to claim 1, characterized in that, The first disc body (10) includes a first frame (101) and a first fluid-blocking fluid (102) circumferentially disposed within the first frame (101), the first fluid-blocking fluid (102) being used to block blood flow; The second disc body (20) includes a second frame (201) and a second fluid-blocking fluid (202) circumferentially disposed within the second frame (201), the second fluid-blocking fluid (202) being used to block blood flow; The first skeleton (101), the second skeleton (201) and the waist (30) are all mesh structures; The connecting portion includes a first connecting portion (40), a second connecting portion (50), and / or a third connecting portion (60) and a fourth connecting portion (70); The first connecting part (40) is circumferentially disposed on the side of the first disc body (10) facing the second disc body (20), or circumferentially disposed on the side of the second disc body (20) facing the first disc body (10); The second connecting part (50) is circumferentially disposed on the side of the second disc body (20) facing the first disc body (10), or circumferentially disposed on the side of the first disc body (10) facing the second disc body (20); Both the first connecting part (40) and the second connecting part (50) are used to fix the peripheral tissue (B) of the part to be sealed (A); The third connecting part (60) is circumferentially disposed on the side of the first disk body (10) facing the second disk body (20), or circumferentially disposed on the side of the second disk body facing the first disk body (10); The fourth connecting part (70) is circumferentially disposed on the side of the second disc (20) facing the first disc (10), or circumferentially disposed on the side of the first disc (10) facing the second disc (20); The third connecting part (60) is used in conjunction with the fourth connecting part (70) to fix the peripheral tissue (B) of the part to be sealed (A).

3. The sealing device according to claim 2, characterized in that, The circumferential edges of the first skeleton (101) and the first fluid barrier (102) are rolled inward to form a first overlapping edge (90), and the circumferential edges of the second skeleton (201) and the second fluid barrier (202) are rolled inward to form a second overlapping edge (100). The first overlapping edge (90) and the second overlapping edge (100) are arranged opposite to each other.

4. The sealing device according to claim 3, characterized in that, When the connecting part includes the first connecting part (40), the first connecting part (40) is circumferentially disposed on the side of the first overlapping edge (90) close to the second overlapping edge (100), or circumferentially disposed on the side of the second overlapping edge (100) close to the first overlapping edge (90); When the connecting part includes the second connecting part (50), the second connecting part (50) is circumferentially disposed on the side of the second overlapping edge (100) close to the first overlapping edge (90), or circumferentially disposed on the side of the first overlapping edge (90) close to the second overlapping edge (100); When the connecting portion includes the first connecting portion (40) and the second connecting portion (50), the first connecting portion (40) is circumferentially disposed on the side of the first overlapping edge (90) near the second overlapping edge (100), and the second connecting portion (50) is circumferentially disposed on the side of the second overlapping edge (100) near the first overlapping edge (90); or the first connecting portion (40) is circumferentially disposed on the side of the second overlapping edge (100) near the first overlapping edge (90), and the second connecting portion (50) is circumferentially disposed on the side of the first overlapping edge (90) near the second overlapping edge (100); the first connecting portion (40) and the second connecting portion (50) are arranged opposite to each other and staggered.

5. The sealing device according to claim 4, characterized in that, The first connecting part (40) includes one or more turns of first barb (401), and the second connecting part (50) includes one or more turns of second barb (501).

6. The sealing device according to claim 5, characterized in that, When the first barb (401) has multiple turns, the multiple turns of the first barb (401) are arranged radially at intervals, and each turn of the first barb (401) includes multiple first barbs (401) arranged circumferentially at intervals. When the second barb (501) has multiple turns, the multiple turns of the second barb (501) are arranged radially at intervals, and each turn of the second barb (501) includes multiple second barbs (501) arranged circumferentially at intervals.

7. The sealing device according to claim 5, characterized in that, Both the first barb (401) and the second barb (501) include a first fixed end (110), a first connecting body (120), and a first hook portion (130). The first fixed end (110) is connected to the first hook portion (130) through the first connecting body (120). The first hook portion (130) is disposed outside the first frame (101) and / or the second frame (201) for fixing and connecting the peripheral tissue (B) of the part to be sealed (A). The first fixed end (110) of the first barb (401) is connected to the first fixed end (110) of the second barb (501) and the first fixed end (110) of the second barb (501) is connected to the first fixed end (110) of the second barb (501) and the first hook portion (130) of the third ... The first frame (101) or the first fluid barrier (102) is fixedly connected, or the first fixed end (110) of the first barb (401) is fixedly connected to the second frame (201) or the second fluid barrier (202), the first fixed end (110) of the second barb (501) is fixedly connected to the second frame (201) or the second fluid barrier (202), or the first fixed end (110) of the second barb (501) is fixedly connected to the first frame (101) or the first fluid barrier (102).

8. The sealing device according to claim 7, characterized in that, The first fixed end (110) of the first barb (401) and the first fixed end (110) of the second barb (501) are both flexible planar structures; The first fixed end of the first barb (401) is bonded to the first skeleton (101) or the first fluid barrier (102) by heat pressing, or the first fixed end (110) of the first barb (401) is bonded to the second skeleton (201) or the second fluid barrier (202) by heat pressing. The first fixed end of the second barb (501) is bonded to the second skeleton (201) or the second fluid barrier (202) by heat pressing, or the first fixed end (110) of the second barb (501) is bonded to the first skeleton (101) or the first fluid barrier (102) by heat pressing.

9. The sealing device according to claim 7, characterized in that, The first connector (120) of the first barb (401) and / or the first connector (120) of the second barb (501) are first elastic bodies.

10. The sealing device according to claim 3, characterized in that, When the connecting portion includes the third connecting portion (60) and the fourth connecting portion (70), the third connecting portion (60) is circumferentially disposed on the side of the first overlapping edge (90) near the second overlapping edge (100), and the fourth connecting portion (70) is circumferentially disposed on the side of the second overlapping edge (100) near the first overlapping edge (90); or the third connecting portion (60) is circumferentially disposed on the side of the second overlapping edge (100) near the first overlapping edge (90), and the fourth connecting portion (70) is circumferentially disposed on the side of the first overlapping edge (90) near the second overlapping edge (100); the third connecting portion (60) and the fourth connecting portion (70) are arranged opposite to each other and used in conjunction.

11. The sealing device according to claim 10, characterized in that, The third connecting part (60) includes one or more locking rings, and the fourth connecting part (70) includes one or more third barbs, which are used in conjunction with the locking rings.

12. The sealing device according to claim 11, characterized in that, When the locking ring has multiple turns, the multiple turns of the locking ring are arranged radially at intervals, and each turn of the locking ring includes multiple locking rings arranged circumferentially at intervals. When the third barb has multiple turns, the multiple turns of the third barb are arranged radially at intervals, and each turn of the third barb includes multiple third barbs arranged circumferentially at intervals.

13. The sealing device according to claim 11, characterized in that, The locking ring includes a second fixed end (601), a second connecting body (602), and a ring body (603). The second fixed end (601) is connected to the ring body (603) through the second connecting body (602). The ring body (603) is disposed outside the first frame (101) or the second frame (201). The second fixed end (601) is fixedly connected to the first frame (101) or the first fluid barrier (102), or the second fixed end (601) is fixedly connected to the second frame (201) or the second fluid barrier (202).

14. The sealing device according to claim 13, characterized in that, The third barb includes a third fixed end (701), a third connector (702), a tip (703), and a second hook (704). The third fixed end (701) is connected to the tip through the third connector (702). The tip (703) is used to pass through the peripheral tissue (B) of the part to be sealed (A) and the ring (603). The second hook (704) is located on the third connector (702) near the tip (703) and is used to lock onto the ring (603). The third fixed end (701) is fixedly connected to the second skeleton (201) or the second fluid barrier (202), or the third fixed end (701) is fixedly connected to the first skeleton (101) or the first fluid barrier (102).

15. The sealing device according to claim 14, characterized in that, Both the second fixed end (601) and the third fixed end (701) are flexible planar structures; The second fixed end (601) is bonded to the first frame (101) or the first fluid barrier (102) by hot pressing, and the third fixed end (701) is bonded to the second frame (201) or the second fluid barrier (202) by hot pressing. Alternatively, the third fixed end (701) can be hot-pressed onto the first frame (101) or the first fluid barrier (102), and the second fixed end (601) can be hot-pressed onto the second frame (201) or the second fluid barrier (202).

16. The sealing device according to claim 14, characterized in that, The second connector (602) and / or the third connector (702) are second elastic bodies.

17. The sealing device according to claim 3, characterized in that, The intercept of the first overlapping edge (90) on the first frame (101) is less than the intercept of the rest of the first frame (101), the intercept of the second overlapping edge (100) on the second frame is less than the intercept of the rest of the second frame (201), and the intercept of the waist (30) is less than the intercept of the rest of the first frame (101) excluding the first overlapping edge (90) and / or less than the intercept of the rest of the second frame (201) excluding the second overlapping edge (100).

18. The sealing device according to claim 3, characterized in that, The height of the first overlapping edge (90) is greater than or equal to 6 times the wire diameter, and the height of the second overlapping edge (100) is greater than or equal to 6 times the wire diameter.

19. The sealing device according to claim 2, characterized in that, The waist (30) is provided with a third flow-blocking fluid (140) in the inner circumferential direction for blocking blood flow.

20. The sealing device according to claim 2, characterized in that, The first disc body (10) has a first protrusion (103) in the middle, which protrudes away from the second disc body (20). The second disc body (20) has a second protrusion (203) in the middle, which protrudes away from the first disc body (10).

21. The sealing device according to claim 20, characterized in that, The first protrusion (103) has a first concave surface (104) inside, and the second protrusion (203) has a second concave surface (204) inside. The first concave surface (104) and the second concave surface (204) are arranged opposite to each other.

22. The sealing device according to claim 2, characterized in that, The second frame (201) is provided with a connecting rivet (150) in the middle.

23. The sealing device according to claim 2, characterized in that, The first disc body (10), the second disc body (20) and the waist (30) are all made of elastic material and / or memory material.

24. The sealing device according to claim 23, characterized in that, The first disc body (10), the second disc body (20) and the waist part (30) are all made of biodegradable materials.

25. The sealing device according to claim 1, characterized in that, The sites to be sealed (A) include aortic dissection rupture (A1), atrial septal defect (A2), patent foramen ovale defect (A3), ventricular septal defect (A4) and / or patent ductus arteriosus defect.

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