Isolation system, control method and biochip between microvalve and liquid

An isolation system and micro-valve technology, applied in fluid controllers, chemical instruments and methods, valve devices, etc., can solve the problems of inability to achieve precise control, increase the difficulty of chip manufacturing, and inability to achieve micron level, and achieve industrialization. Chemical production and practical application, good fluid flow patency, single wavelength effect

CN108679301BActive Publication Date: 2019-01-08HUNAN LEGEND AI CHIP BIOTECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2019-01-08

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Abstract

The invention discloses an isolation system between a microvalve and a liquid, a control method and a biochip. The isolation system between the microvalve and the liquid includes a reagent chamber, a first pipeline, a second pipeline and a reaction chamber; the reagent chamber is used to store liquid, and the liquid outlet of the reagent chamber is connected to the first pipeline One end communicates, the other end of the first pipeline is separated from one end of the second pipeline by a normally closed microvalve, and the other end of the second pipeline communicates with the reaction chamber; there is an air column in the first pipeline, One end of the air column contacts the normally closed microvalve, the other end of the air column contacts the liquid, and the first pipeline communicates with the second pipeline when the normally closed microvalve is opened. The invention ensures that the liquid will not flow into the microvalve during the storage process, and the storage liquid will not be affected during the change of the microvalve.
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Description

technical field

[0001] The invention relates to an isolation system between a microvalve and a liquid, a control method and a biochip, belonging to the field of biochip detection. Background technique

[0002] Microfluidic chip technology integrates the basic operation units such as sample preparation, reaction, separation, and detection in the process of biological, chemical, and medical analysis into a micron-scale chip to automatically complete the entire analysis process. Due to its great potential in the fields of biology, chemistry, and medicine, it has developed into a new research field interdisciplinary in biology, chemistry, medicine, fluid, electronics, materials, and machinery.

[0003] At present, the reagents used in microfluidic chips are mostly injected externally, and driven by external forces, the reagents flow according to the pipeline. Now the microfluidic chip detection reagent is added into the chip reagent chamber in advance, no need to inject the rea...

Examples

Embodiment Construction

[0044] The present invention will be described in detail below with reference to the accompanying drawings and examples. It should be noted that, in the case of no conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other. For the convenience of description, if the words "up", "down", "left" and "right" appear in the following, it only means that the directions of up, down, left and right are consistent with the drawings themselves, and do not limit the structure.

[0045] An isolation system between a microvalve and a liquid, such as Figure 1-3 , 7,8, which includes a reagent chamber 1, a first pipeline 4, a second pipeline 9 and a reaction chamber 8. The reagent chamber 1 , the first pipeline 4 , the second pipeline 9 and the reaction chamber 8 are all set in the chip base 7 . The reagent chamber 1 is used to store the liquid 3, the bottom end of the reagent chamber 1 communicates with one end of the first pipel...