A biochemical analyzer
By introducing sample delivery, incubation and sampling mechanisms into the biochemical analyzer, the automatic transmission, heating and processing of samples is achieved, and the problem of low automation in the prior art is solved, and the convenience and efficiency of detection are improved.
Patent Information
- Application Number
- CN201810922729.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2018-08-14
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2038-08-14
AI Technical Summary
The existing biochemical analyzers have low degree of automation, and many operating processes require manual intervention, resulting in inconvenience in testing.
A biochemical analyzer including a sample delivery mechanism, an incubation mechanism and a sampling mechanism is designed to automatically transfer, heat and process the samples through these mechanisms, and finally fully automated inspection is carried out.
The full automation of sample detection is realized, which greatly improves the convenience and efficiency of detection and reduces the need for manual intervention.
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Figure CN109061212B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of medical instruments, and more specifically, to a biochemical analyzer. Background Art
[0002] Biochemical analyzer is a kind of clinical biochemical and pathological testing equipment. It mainly provides physicians with relevant parameters of clinical biochemistry, clinical hematology, clinical immunology and other projects, so as to cooperate with the testing of clinical biochemical indicators such as liver function, kidney function, blood lipids, myocardial enzyme spectrum, protein, etc. for patients, providing important scientific basis for physicians in the diagnosis, treatment and prevention of diseases, and is also an essential testing equipment for hospitals to carry out clinical diagnosis. At present, as one of the important instruments frequently used in clinical testing, biochemical analyzer has been widely used in various large and medium-sized hospitals, providing essential information basis for clinical diagnosis, treatment, prognosis and health status of diseases, and becoming an indispensable standard instrument for large and medium-sized hospitals.
[0003] In actual operation, due to the limitations of the structural design of existing biochemical analyzers, the automation level of existing biochemical analyzers is often not high, and many operation processes require manual operation by staff, which brings great inconvenience to the detection work. Summary of the invention
[0004] The technical problem to be solved by the present invention is to provide a biochemical analyzer which, through its structural design, can fully automate sample detection and greatly improve the convenience of detection.
[0005] A biochemical analyzer comprises a base, wherein a sample delivery mechanism is arranged above the base, the sample delivery mechanism is used for delivering samples to be tested, an incubation mechanism is arranged in the transmission direction of the sample delivery mechanism, the incubation mechanism is used for incubating and heating the samples to be tested, a sampling mechanism is arranged behind the incubation mechanism, the sampling mechanism is used for absorbing and processing the samples to be tested, and a detection mechanism is arranged behind the sampling mechanism, the detection mechanism is used for detecting the samples.
[0006] Preferably, a shell is arranged above the base, and the shell covers the incubation mechanism, the sampling mechanism and the detection mechanism.
[0007] Preferably, the sample feeding mechanism comprises a motor, a screw rod and a slide, the motor is connected to a horizontally arranged screw rod, the screw rod is connected to the slide rod movable along the screw rod, and the slide rod is used for supporting and fixing an external sample container.
[0008] Preferably, a reagent card is provided on the sample delivery mechanism, and the reagent card includes a card body, and the card body is provided with a sample chamber, a sampling needle holder, a cleaning chamber, a reagent chamber, and a detection chamber. The sample chamber is used for carrying the sample to be tested, the sampling needle holder is used for carrying the sampling needle, the cleaning chamber is used for cleaning the sampling needle, the reagent chamber is used for storing reagents required for sample testing, and the detection chamber is used for mixing and testing the sample and the reagent.
[0009] Preferably, the incubation mechanism includes a base plate, a first heating plate is arranged on the left side above the base plate, a second heating plate is arranged on the right side above the base plate, a cover plate is arranged above the first heating plate and the second heating plate, the base plate, the first heating plate, the second heating plate and the cover plate surround an incubation cavity, a fan is arranged in the incubation cavity, and a channel opening for installing the sample delivery mechanism to facilitate the entry and exit of samples to be incubated is arranged at the front end or the rear end of the incubation cavity.
[0010] Preferably, the sampling mechanism comprises a support frame arranged above the sample delivery mechanism, the support frame is provided with a positioning block, a suction head is provided at the positioning block, a suction nozzle is connected to the rear of the suction head, a suction tube is connected to the rear of the suction nozzle, and a micro pump is connected to the rear of the suction tube.
[0011] Preferably, a capping mechanism is provided at the sampling mechanism, and the capping mechanism is used to separate the suction head from the suction nozzle. The capping mechanism includes a positioning plate, a bayonet is provided on the positioning plate, and a capping clamp is provided in the bayonet, and the capping clamp is used to clamp and fix the suction head to be separated. A horizontal motion component is provided at the rear of the capping clamp, and the horizontal motion component is used to drive the capping clamp to move in the horizontal direction. A vertical motion component is provided in front of the capping clamp, and the vertical motion component is used to drive the suction nozzle to be separated to move in the up and down directions.
[0012] Preferably, a fixing frame is arranged behind the positioning plate, the cap removal clip is embedded in the fixing frame, and a return spring is arranged between the positioning plate and the fixing frame.
[0013] The beneficial effects of the present invention are as follows: the biochemical analyzer provided by the present invention realizes the transmission of the sample to be detected through the sample delivery mechanism, then utilizes the incubation mechanism to incubate and heat the sample to be detected, then uses the sampling mechanism to absorb and process the sample to be detected, and finally realizes the detection of the sample through the detection mechanism, thereby enabling full automation of sample detection and greatly improving the convenience of detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.
[0015] Figure 1 This is a schematic diagram of the overall structure of the biochemical analyzer disclosed in Example 1 of the present invention;
[0016] Figure 2 This is a schematic diagram of an explosion of the biochemical analyzer disclosed in Example 1 of the present invention;
[0017] Figure 3 It is a structural schematic diagram of the sample delivery mechanism disclosed in Example 2 of the present invention;
[0018] Figure 4 It is a front view of the reagent card disclosed in Example 3 of the present invention;
[0019] Figure 5 A top view of the reagent card disclosed in Example 3 of the present invention;
[0020] Figure 6 This is a schematic diagram of the overall structure of the incubation mechanism disclosed in Example 4 of the present invention;
[0021] Figure 7 This is an exploded schematic diagram of the incubation mechanism disclosed in Example 4 of the present invention;
[0022] Figure 8 This is a schematic diagram of the structure of the sampling mechanism disclosed in Example 5 of the present invention;
[0023] Fig. 9 This is an exploded schematic diagram of the cap-removing mechanism disclosed in Example 6 of the present invention. DETAILED DESCRIPTION
[0024] In order to enable those skilled in the art to better understand the technical solutions in the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without creative work should fall within the scope of protection of the present application.
[0025] In the description of the present invention, it is necessary to understand that the terms "above", "horizontal", "vertical", "front", "rear", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.
[0026] Embodiment 1:
[0027] See also Figure 1 and Figure 2 , Figure 1 and Figure 2 A specific embodiment of a biochemical analyzer of the present invention is provided, wherein: Figure 1 This is a schematic diagram of the overall structure of the biochemical analyzer disclosed in Example 1 of the present invention; Figure 2 This is a schematic diagram of an explosion of the biochemical analyzer disclosed in Example 1 of the present invention.
[0028] like Figure 1 and Figure 2 As shown, the biochemical analyzer provided by the present invention includes a base 1, a sample delivery mechanism 2, an incubation mechanism 3, a sampling mechanism 4 and a detection mechanism 5.
[0029] In this solution, the biochemical analyzer includes a base 1, which is used to carry components such as a sample delivery mechanism 2, an incubation mechanism 3, a sampling mechanism 4, and a detection mechanism 5. The specific shape of the base 1 is selected and designed according to actual needs.
[0030] A sample delivery mechanism 2 is arranged above the base 1, and the sample delivery mechanism 2 is used for transmitting the sample to be detected. Specifically, the sample delivery mechanism 2 not only transmits the sample to be detected, but also transmits the reaction reagents required for the detection process of the sample to be detected. Among them, the sample and the reagent are generally carried in a special reagent card 6.
[0031] An incubation mechanism 3 is provided in the transmission direction of the sample delivery mechanism 2, and the incubation mechanism 3 is used for incubating and heating the sample to be detected. Specifically, the incubation mechanism 3 is provided to provide a prescribed constant temperature for the sample or reagent, so as to facilitate the subsequent detection of the sample itself or the reaction between the sample and the reagent.
[0032] A sampling mechanism 4 is arranged behind the incubation mechanism 3, and the sampling mechanism 4 is used for sucking and processing the sample to be detected. Specifically, in actual operation, the sampling mechanism 4 can not only suck the sample, but also suck the reagent, and can also suck the sample and the reagent together into a special detection chamber for reaction and detection. The specific sampling situation of the sampling mechanism 4 is determined according to the items to be detected by the sample.
[0033] A detection mechanism 5 is arranged behind the sampling mechanism 4, and the detection mechanism 5 is used for detecting the sample. The detection mechanism 5 can detect the sample by colorimetry or turbidimetry.
[0034] In this embodiment, in order to further achieve the safety range of the mechanism and prevent external substances from contaminating samples or reagents, preferably, a shell 8 is provided above the base 1, and the shell 8 is provided on the incubation mechanism 3, the sampling mechanism 4, and the detection mechanism 5. Among them, the sample delivery mechanism 2 generally penetrates inside and outside the shell 8, so as to deliver the external sample into the shell 8 for detection.
[0035] In general, the biochemical analyzer provided by the present invention realizes the transmission of the sample to be detected through the sample delivery mechanism 2, then utilizes the incubation mechanism 3 to incubate and heat the sample to be detected, then uses the sampling mechanism 4 to absorb and process the sample to be detected, and finally realizes the detection of the sample through the detection mechanism 5, thereby enabling full automation of sample detection and greatly improving the convenience of detection.
[0036] Embodiment 2:
[0037] See also Figure 3 , Figure 3 A specific embodiment of a sample delivery mechanism is provided, wherein: Figure 3 This is a schematic diagram of the structure of the sample delivery mechanism disclosed in Example 1 of the present invention.
[0038] like Figure 3 As shown, the sample feeding mechanism 2 provided in this embodiment includes a motor 201, a screw rod 202, and a slide 203. The motor 201 is connected to a horizontally arranged screw rod 202, and the screw rod 202 is connected to the slide 203 that can move along the screw rod 202. The slide 203 is used to support and fix the external sample container.
[0039] Specifically, the motor 201 is used to provide power for the rotation of the screw rod 202, so that the screw rod 202 can drive the slide 203 to slide along the screw rod 202, and the slide 203 can further drive the sample container arranged above it to move.
[0040] In this embodiment, in order to further achieve stable transmission of the sample container in the horizontal direction, preferably, linear shafts are horizontally spaced apart on both sides of the screw rod 202, and linear bearings are provided on the slide 203, and the linear shafts are inserted into the linear bearings.
[0041] In this embodiment, in order to further facilitate the support and fixation of the sample container, preferably, a fixing frame is provided on the slide 203, and the fixing frame is used to fix the external sample container.
[0042] Embodiment 3:
[0043] See also Figure 4 and Figure 5 , Figure 4 and Figure 5 A specific embodiment of a reagent card is provided, wherein: Figure 4 It is a front view of the reagent card disclosed in Example 3 of the present invention; Figure 5 This is a top view of the reagent card disclosed in Example 3 of the present invention.
[0044] In the specific implementation process, in order to facilitate the entry of samples and reagents into the biochemical analyzer, the samples and reagents are often stored in special containers. This embodiment provides a reagent card specifically for storing samples and reagents.
[0045] In this embodiment, the reagent card is generally mounted on the slide described in Example 2. The reagent card 6 provided in this embodiment includes a card body 601, on which a sample chamber 602, a sampling needle support 603, a cleaning chamber 604, a reagent chamber 605, and a detection chamber 606 are provided. The sample chamber 602 is used for carrying the sample to be detected, the sampling needle support 603 is used for carrying the sampling needle 607, the cleaning chamber 604 is used for cleaning the sampling needle 607, the reagent chamber 605 is used for storing the reagents required in the sample detection, and the detection chamber 606 is used for mixing and detecting the sample and the reagent. Wherein, the sampling needle 607 can generally be matched and connected with the sampling mechanism 4.
[0046] The specific arrangement of the sample chamber 602, the sampling needle support 603, the cleaning chamber 604, the reagent chamber 605, and the detection chamber 606 is based on the convenience of operation. In the accompanying drawings provided in this embodiment, the card body 601 is arranged from the left end to the right end with a sample chamber 602 → a cleaning chamber 604 → a sampling needle support 603 → a cleaning chamber 604 → four reagent chambers 605 (each reagent chamber 605 generally stores different reagents) → four detection chambers 606 (each detection chamber 606 is generally used for mixed detection of different reagents). Of course, other arrangements can also be used.
[0047] In this solution, the sample cavity 602 is used to carry the sample to be detected. To further facilitate the carrying and aspiration of the sample, the sample cavity 602 provided in this embodiment is preferably a funnel-shaped sample cavity.
[0048] In this solution, the sampling needle support 603 is used to carry the sampling needle 607. Specifically, an interface matching the suction head of an external fully automatic biochemical analyzer is generally provided above the sampling needle 607, so that when the reagent card is pushed into the fully automatic biochemical analyzer, the suction head of the fully automatic biochemical analyzer can directly suck the sampling needle 607 to move, thereby moving in the sample chamber 602, the cleaning chamber 604, the reagent chamber 605, and the detection chamber 606 to perform sample detection operations.
[0049] In this solution, the cleaning chamber 604 is used to store cleaning liquid to facilitate the cleaning of the sampling needle 607, so that the sampling needle 607 can be cleaned every time it samples or absorbs reagents, effectively avoiding the interference between different reagents. To further facilitate the cleaning of the sampling needle 607, the drawings provided in this embodiment provide a cleaning chamber 604 at both ends of the sampling needle bracket 603.
[0050] In this solution, the reagent chamber 605 is used to store reagents required for sample detection. Specifically, this embodiment is designed with four reagent chambers 605, each of which can store different reagents.
[0051] In this solution, the detection chamber 606 is used for mixing and detecting the sample and the reagent. Specifically, four detection chambers 606 are designed in this embodiment, wherein each detection chamber 606 can be used for detecting different index parameters of the sample.
[0052] In general, the reagent card provided by the present invention carries the sample to be tested through the sample cavity 602 and the reagent cavity 605 to store the reagents required for sample testing, and then uses the sampling needle 607 on the sampling needle holder 603 to draw the sample and reagent into the detection cavity 606 for mixing and testing. At the same time, the sampling needle 607 is cleaned through the cleaning cavity 604 before each sample or reagent is drawn, thereby facilitating the addition of reagents, effectively realizing the detection of various parameters of the sample, and improving the detection efficiency.
[0053] Embodiment 4:
[0054] See also Figure 6 and Figure 7 , Figure 6 and Figure 7 A specific embodiment of an incubation mechanism is provided, wherein: Figure 6 This is a schematic diagram of the overall structure of the incubation mechanism disclosed in Example 4 of the present invention; Figure 7 This is an exploded schematic diagram of the incubation mechanism disclosed in Example 4 of the present invention.
[0055] like Figure 6 As shown in Figure 7, the incubation mechanism 3 provided in this embodiment includes a base plate 301, a first heating plate 302 is arranged on the left side above the base plate 301, a second heating plate 303 is arranged on the right side above the base plate 301, a cover plate 304 is arranged above the first heating plate 302 and the second heating plate 303, the base plate 301, the first heating plate 302, the second heating plate 303 and the cover plate 304 surround to form an incubation cavity, a fan 305 is arranged in the incubation cavity, and a channel opening 306 for installing the sample feeding mechanism 2 to facilitate the entry and exit of the samples to be incubated is arranged at the front end or the rear end of the incubation cavity 305.
[0056] Specifically, the incubation mechanism provided in this embodiment includes a bottom plate 301 , a first heating plate 302 , a second heating plate 303 , a cover plate 304 , a fan 305 and a passage opening 306 .
[0057] In this solution, the bottom plate 301 , the first heating plate 302 , the second heating plate 303 and the cover plate 304 surround and form an incubation cavity, and the incubation cavity is used to provide an incubation space for the sample to be detected.
[0058] The bottom plate 301 is used for supporting, and the specific structure and shape of the bottom plate 301 is selected and designed according to actual needs.
[0059] A first heating plate 302 is disposed on the left side above the bottom plate 301, and a second heating plate 303 is disposed on the right side above the bottom plate 301. The first heating plate 302 and the second heating plate 303 are used to radiate heat required for incubation of the sample to be tested from the left and right sides to the incubation chamber. Specifically, the sample temperature generally needs to be ensured to reach 37.5 degrees.
[0060] A cover plate 304 is disposed above the first heating plate 302 and the second heating plate 303 , and the cover plate 304 is used for sealing and protecting.
[0061] A fan 305 is provided in the incubation chamber, and the fan 305 is used to supply air to the incubation chamber, thereby increasing the air flow speed in the incubation chamber and accelerating the temperature rise speed of the sample to be detected.
[0062] A channel opening 306 for the incubated sample to enter and exit is provided at the front end or the rear end of the incubation chamber.
[0063] During the specific implementation of the incubation mechanism provided in this embodiment, the first heating plate 302 and the second heating plate 303 will provide heat to the sample from the left and right sides at the same time, and the fan 305 will supply air to accelerate the air flow in the incubation chamber, so that samples at various heights can be heated at the same time, thereby improving the heating efficiency and effectively ensuring the heating quality.
[0064] In this embodiment, in order to further ensure the temperature balance of each part in the incubation chamber, preferably, the air supply direction of the fan 305 is the front-to-back direction.
[0065] Embodiment 5:
[0066] See also Figure 8 , Figure 8 A specific embodiment of a sampling mechanism is provided, wherein: Figure 8 This is a schematic diagram of the structure of the sampling mechanism disclosed in Example 5 of the present invention.
[0067] like Figure 8As shown, the sampling mechanism 4 provided in this embodiment includes a support frame 401 arranged above the sample delivery mechanism, a positioning block 402 is arranged on the support frame 401, a suction head 403 is arranged at the positioning block 402, a suction nozzle 404 is connected to the rear of the suction head 403, a suction tube 405 is connected to the rear of the suction nozzle 404, and a micro pump 406 is connected to the rear of the suction tube 405.
[0068] Specifically, the positioning block 402 is used to monitor the position of the sample to be detected, so as to accurately monitor the position of the sample to be detected and ensure that the sample container can be moved directly below the suction head 403. The suction head 403 is used to suck the reagent or sample or the mixture of the reagent and the sample, and the micro pump 406 is used to provide the power required for suction and control the suction amount.
[0069] During the specific implementation process:
[0070] First, a sample container loaded with a sample to be tested is fixed on the sample delivery mechanism 2, and the sample delivery mechanism 2 starts to deliver the sample, thereby transferring the sample container to the position where the suction head 403 is located;
[0071] Then, the vacuum force provided by the micro pump 406 is transmitted to the suction head 403, and the suction head 403 can transfer the sample and reagent in the sample container to a special test cup for mixing;
[0072] Finally, the suction head 403 delivers the mixed solution into the test channel for testing, and after the test is completed, the sample delivery mechanism 2 delivers the sample container, thereby realizing the automation of the entire workflow.
[0073] Embodiment 6:
[0074] See also Fig. 9 , Fig. 9 A specific embodiment of a cap removal mechanism is provided, wherein: Fig. 9 This is an exploded schematic diagram of the cap-removing mechanism disclosed in Example 6 of the present invention.
[0075] like Fig. 9 As shown, the sampling mechanism 4 provided in this embodiment is provided with a cap-removing mechanism 7, and the cap-removing mechanism 7 is used for separating the suction head and the suction nozzle described in Example 5, and the cap-removing mechanism 7 comprises a positioning plate 701, and a bayonet 702 is provided on the positioning plate 701, and a cap-removing clip 703 is provided in the bayonet 702, and the cap-removing clip 703 is used for clamping and fixing the suction head to be separated, and a horizontal motion component 704 is provided at the rear of the cap-removing clip 703, and the horizontal motion component 704 is used to drive the cap-removing clip 703 to move in the horizontal direction, and a vertical motion component 705 is provided in front of the cap-removing clip 703, and the vertical motion component 705 is used to drive the suction nozzle to be separated to move in the up and down directions.
[0076] In addition, the positioning plate 701 in this embodiment may be the same component as the positioning block 402 in Embodiment 5, or may be a different component.
[0077] Specifically, the cap removal mechanism provided in the embodiment of the present invention includes a positioning plate 701 , a bayonet 702 , a cap removal clamp 703 , a horizontal motion component 704 , and a vertical motion component 705 .
[0078] In this embodiment, the positioning plate 701 is used to provide positioning for the separation of the suction head and the suction nozzle. In other words, a predetermined position is provided for the separation of the suction head and the suction nozzle, and when the suction head and the suction nozzle move to the position, the system starts the separation of the suction head and the suction nozzle.
[0079] A bayonet 702 is provided on the positioning plate 701 , and a cap removal clamp 703 is provided in the bayonet 702 . The cap removal clamp 703 is used for clamping and fixing the suction head to be separated.
[0080] A horizontal motion component 704 is disposed at the rear of the cap removal clip 703, and the horizontal motion component 704 is used to drive the cap removal clip 703 to move in a horizontal direction. Specifically, the directional word rear used in this embodiment is the left side of the drawing.
[0081] A vertical motion assembly 705 is provided in front of the cap removal clamp 703, and the vertical motion assembly 705 is used to drive the suction nozzle 7 to be separated to move in the up and down direction. Specifically, the directional word "front" used in this embodiment is the right side of the drawing.
[0082] During the specific implementation, when the assembly of the suction head and the suction nozzle moves to the positioning plate 701, the horizontal motion component 704 drives the cap removal clamp 703 to move horizontally along the clamping opening 702 until the clamping opening of the cap removal clamp 703 clamps the suction head, and then the vertical motion component 705 drives the suction nozzle to move upward. During this process, since the suction head has been clamped by the cap removal clamp 703, the suction nozzle will be separated from the suction head when it is driven upward by the vertical motion component 705. Specifically, in order to further facilitate the clamping of the suction head by the cap removal clamp 703, the suction head described in this embodiment is generally small at the top and large at the bottom, and the clamping opening of the cap removal clamp 703 described in this embodiment is a U-shaped clamping opening.
[0083] In this embodiment, in order to further facilitate the simultaneous separation of multiple groups of suction heads and suction nozzles, preferably, at least two decapping clips 703 are provided. The accompanying drawings provided in this embodiment show that two decapping clips 703 are provided.
[0084] In this embodiment, in order to further facilitate the guidance of the cap removal clip 703 during movement, preferably, a fixing frame 706 is provided behind the positioning plate 701, and the cap removal clip 703 is embedded in the fixing frame.
[0085] In this embodiment, in order to further facilitate the decapping clamp 703 to return to its original position in time after completing the separation operation of the suction head and the suction nozzle, preferably, a return spring 707 is provided between the positioning plate 701 and the fixing frame 706 .
[0086] In this embodiment, a barcode scanner is provided between the horizontal motion component 704 and the cap removal clamp 703 , and the barcode scanner is used to identify the information of the suction head to be separated.
[0087] In addition, considering that a sealing film is generally provided on the top of some sample carriers, a membrane rupturing needle may also be provided on the vertical motion component 705 in this embodiment.
[0088] The above is a detailed introduction to a biochemical analyzer provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention, and the description of the above embodiments is only used to help understand the method of the present invention and its core idea. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the present invention, the present invention can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.
Claims
1. A biochemical analyzer, characterized in that: It comprises a base, a sample delivery mechanism is arranged above the base, the sample delivery mechanism is used to deliver the sample to be tested, an incubation mechanism is arranged in the delivery direction of the sample delivery mechanism, the incubation mechanism is used to incubate and heat the sample to be tested, a sampling mechanism is arranged behind the incubation mechanism, the sampling mechanism is used to absorb and process the sample to be tested, and a detection mechanism is arranged behind the sampling mechanism, the detection mechanism is used to detect the sample; The incubation mechanism comprises a bottom plate, a first heating plate is arranged on the left side above the bottom plate, a second heating plate is arranged on the right side above the bottom plate, a cover plate is arranged above the first heating plate and the second heating plate, an incubation chamber is formed around the bottom plate, the first heating plate, the second heating plate and the cover plate, a fan is arranged in the incubation chamber, and a channel opening for installing the sample delivery mechanism to facilitate the entry and exit of the samples to be incubated is arranged at the front end or the rear end of the incubation chamber; The sample delivery mechanism is provided with a reagent card, and the reagent card includes a card body, and the card body is provided with a sample cavity, a sampling needle holder, a cleaning cavity, a reagent cavity, and a detection cavity. The sample cavity is used to carry the sample to be detected, the sampling needle holder is used to carry the sampling needle, the cleaning cavity is used to clean the sampling needle, the reagent cavity is used to store the reagents required for sample detection, and the detection cavity is used for mixing and detecting the sample and the reagent; There are multiple reagent chambers, multiple detection chambers, each of which stores different reagents, and each of which is used for mixed detection of different reagents; The sampling mechanism is provided with a cap-removing mechanism, which is used to separate the suction head from the suction nozzle. The cap-removing mechanism includes a positioning plate, a bayonet is provided on the positioning plate, a cap-removing clip is provided in the bayonet, and the cap-removing clip is used to clamp and fix the suction head to be separated. A horizontal motion component is provided at the rear of the cap-removing clip, and the horizontal motion component is used to drive the cap-removing clip to move in the horizontal direction. A vertical motion component is provided in front of the cap-removing clip, and the vertical motion component is used to drive the suction nozzle to be separated to move in the up and down direction; A fixing frame is arranged behind the positioning plate, the cap removal clip is embedded in the fixing frame, and a return spring is arranged between the positioning plate and the fixing frame.
2. The biochemical analyzer according to claim 1, characterized in that: A shell is arranged above the base, and the shell covers the incubation mechanism, the sampling mechanism and the detection mechanism.
3. The biochemical analyzer according to claim 1, characterized in that: The sample delivery mechanism comprises a motor, a screw rod and a slide. The motor is connected to the screw rod which is arranged horizontally. The screw rod is connected to the slide which can move along the screw rod. The slide is used for supporting and fixing the external sample container.
4. The biochemical analyzer according to claim 1, characterized in that: The sampling mechanism comprises a support frame arranged above the sample delivery mechanism, a positioning block is arranged on the support frame, a suction head is arranged at the positioning block, a suction nozzle is connected to the rear of the suction head, a suction pipe is connected to the rear of the suction nozzle, and a micro pump is connected to the rear of the suction pipe.
Citation Information
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