A 3D printed personalized acromioclavicular joint replacement prosthesis and preparation method thereof

Abstract

The present invention provides a 3D-printed personalized acromioclavicular joint replacement prosthesis and a preparation method thereof, wherein the acromioclavicular joint replacement prosthesis comprises an acromioclavicular joint replacement prosthesis body, a clavicular acromion end connector and a scapula infraspinous fossa connector, wherein the acromioclavicular joint replacement prosthesis body and the clavicular acromion end connector are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body and the scapula infraspinous fossa connector are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body is customized according to the defective bone tissue of the patient. The acromioclavicular joint replacement prosthesis of the present invention completely replaces the acromion of the scapula, firmly connects the infraspinous fossa of the scapula and the acromion end of the clavicle, and completes the restoration of the original bone morphology to the greatest extent.

Description

Technical Field

[0001] The present invention belongs to the technical field of acromioclavicular joint prostheses, and in particular relates to a 3D printed personalized acromioclavicular joint replacement prosthesis and a preparation method thereof. Background Art

[0002] Acromioclavicular joint bone tumor is one of the common sites of shoulder girdle tumors and requires surgical resection. The traditional surgical method is upper quarter amputation, but upper limb prostheses cannot replace the important functions of the hand, so limb salvage is particularly important in saving upper limb function. Currently, the methods of limb salvage surgery for shoulder girdle tumors include: artificial prosthesis replacement, autologous iliac bone scapula reconstruction, allogeneic bone or bone joint transplantation, joint fusion and boneless reconstruction.

[0003] However, the current acromioclavicular joint prosthesis cannot make up for the large bone defect of the scapula, and surgical repair and reconstruction are difficult. The prosthesis does not match the original bone morphology and cannot be accurately reconstructed.

[0004] At the same time, the current acromioclavicular joint prosthesis adopts the traditional subtractive manufacturing method. The prosthesis cannot be integrated with the surrounding bones, and does not have functions such as biological fixation. There is a possibility of long-term fixation loosening of the prosthesis. In addition, the attachment points such as tendons and ligaments cannot grow together with the prosthesis, and the normal physiological kinematic behavior of the knee joint cannot be reconstructed. Summary of the invention

[0005] In view of the shortcomings of the prior art described above, the object of the present invention is to provide a 3D-printed personalized acromioclavicular joint replacement prosthesis and a preparation method thereof, wherein the acromioclavicular joint replacement prosthesis comprises an acromioclavicular joint replacement prosthesis body, a clavicular acromial end connector and a scapula infraspinous fossa connector, wherein the acromioclavicular joint replacement prosthesis body and the clavicular acromial end connector are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body and the scapula infraspinous fossa connector are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body is customized according to the defective bone tissue of the patient. The acromioclavicular joint replacement prosthesis of the present invention completely replaces the acromion of the scapula, firmly connects the infraspinous fossa of the scapula and the acromial end of the clavicle, and completes the restoration of the original bone morphology to the greatest extent.

[0006] To achieve the above-mentioned purpose and other related purposes, the first aspect of the present invention provides an acromioclavicular joint replacement prosthesis, including an acromioclavicular joint replacement prosthesis body, a clavicular acromial end connector and a scapular infraspinous fossa connector, the acromioclavicular joint replacement prosthesis body and the clavicular acromial end connector are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body and the scapular infraspinous fossa connector are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body is customized according to the patient's defective bone tissue, that is, the acromioclavicular joint replacement prosthesis body is in the shape of the defective bone tissue of the acromioclavicular joint, and is completely matched with the patient's defective bone tissue of the acromioclavicular joint.

[0007] Preferably, the acromioclavicular joint replacement prosthesis body is provided with a first cavity matching the medullary cavity of the scapula osteotomy surface, and the acromioclavicular joint replacement prosthesis body is concave inward at the end of the connector near the infraspinous fossa of the scapula to form the first cavity.

[0008] Preferably, the acromioclavicular joint replacement prosthesis body is provided with a first end face and a second end face at the clavicle acromion end connector end and the scapula infraspinous fossa connector end, respectively; the clavicle acromion end connector is provided with a first covering surface, the first covering surface faces the clavicle acromion end; the scapula infraspinous fossa connector is provided with a second covering surface, the second covering surface faces the scapula infraspinous fossa; the first end face is smoothly connected to the first covering surface, and the second end face is smoothly connected to the second covering surface.

[0009] More preferably, it further comprises a plurality of first screw holes, wherein the first screw holes penetrate through the clavicle acromion end connector, and the first screw holes are used to fix the acromioclavicular joint replacement prosthesis to the clavicle acromion end via screws.

[0010] More preferably, it further comprises a plurality of second screw holes, wherein the second screw holes penetrate through the infraspinous fossa of the scapula connecting piece, and the second screw holes are used to fix the acromioclavicular joint replacement prosthesis with the infraspinous fossa of the scapula via screws.

[0011] More preferably, the first end surface, the second end surface, the first covering surface and the second covering surface are a layered structure of several layers, each layer of the layered structure has a plurality of micropores, and the micropores of the layers are interconnected.

[0012] More preferably, it further comprises at least one of the following technical features:

[0013] 1) The pore diameters of the micropores of the first end surface, the second end surface, the first covering surface, and the second covering surface are 600 μm to 800 μm;

[0014] 2) The porosity of the first end surface, the second end surface, the first covering surface and the second covering surface is 60% to 80%; the porosity refers to the percentage of the pore volume to the total volume in the natural state, for example, the porosity of the first end surface refers to the percentage of the pore volume of the first end surface to the total volume of the first end surface in the natural state;

[0015] 3) The first end surface, the second end surface, the first covering surface and the second covering surface have a thickness of 1.5 mm to 2.0 mm.

[0016] Preferably, it also includes a plurality of attachment holes for muscle and ligament attachment points, and the attachment holes pass through the acromioclavicular joint replacement prosthesis body.

[0017] The second aspect of the present invention provides a method for preparing the acromioclavicular joint replacement prosthesis, comprising the following steps:

[0018] 1) obtaining a model of the acromioclavicular joint, such as a computer aided design model (CAD model);

[0019] 2) Reverse modeling the model obtained in step 1) to obtain an acromioclavicular joint replacement prosthesis model;

[0020] 3) Perform 3D printing based on the repair device model.

[0021] Preferably, the method comprises the following steps:

[0022] 1) Obtain acromioclavicular joint model through CT and MRI;

[0023] 2) performing three-dimensional registration and fusion on the model obtained in step 1), and then reverse modeling to obtain an acromioclavicular joint replacement prosthesis model;

[0024] Bones can be observed by CT, and soft tissues can be observed by MRI. The models obtained by the two can be 3D registered and fused to achieve a 3D reconstruction model that includes both bones and soft tissues. Then, reverse modeling can be achieved by existing software, such as E3D. The model after 3D registration and fusion and the model of the acromioclavicular joint as a whole constitute a normal acromioclavicular joint model. The reverse model establishes an acromioclavicular joint replacement prosthesis model based on the normal acromioclavicular joint model and the model after 3D registration and fusion.

[0025] 3) Perform 3D printing based on the repair device model.

[0026] As described above, the present invention has at least one of the following beneficial effects:

[0027] 1) The acromioclavicular joint replacement prosthesis of the present invention is mainly a medical 3D printed personalized prosthesis of the same size produced by reverse modeling based on the patient's CT / MRI and other imaging data, which accurately reconstructs a large amount of defective bone tissue, completely replaces the acromion of the scapula, firmly connects the infraspinous fossa of the scapula and the acromion end of the clavicle, and can maximize the restoration of the original bone morphology;

[0028] 2) The first end face, the second end face, the first covering surface and the second covering surface of the acromioclavicular joint replacement prosthesis of the present invention are closely attached to human bone and are a layered structure with multiple layers. Each layer of the layered structure has a plurality of micropores, and the micropores of the layers are interconnected, which is conducive to the creeping growth of bone cells to cause bone fusion and achieve the purpose of long-term stability;

[0029] 3) The acromioclavicular joint replacement prosthesis of the present invention also includes a plurality of first screw holes, wherein the first screw holes penetrate the clavicle acromial end connector, and the first screw holes are used to fix the acromioclavicular joint replacement prosthesis to the clavicle acromial end via screws; and also includes a plurality of second screw holes, wherein the second screw holes penetrate the scapula infraspinous fossa connector, and the second screw holes are used to fix the acromioclavicular joint replacement prosthesis to the scapula infraspinous fossa via screws. During initial implantation, initial fixation can be performed using orthopedic screws to prevent the prosthesis from shifting. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 The structure of the acromioclavicular joint replacement prosthesis of the present invention is schematically shown. Figure 1 .

[0031] Figure 2 The structure of the acromioclavicular joint replacement prosthesis of the present invention is schematically shown. Figure 2 .

[0032] Figure 3 The structure of the acromioclavicular joint replacement prosthesis of the present invention is schematically shown in the use state Figure 1 .

[0033] Figure 4 The structure of the acromioclavicular joint replacement prosthesis of the present invention is schematically shown in the use state Figure 2 .

[0034] Figure 5 It is a layered structure with multiple micropores.

[0035] Reference numerals:

[0036] 1 Acromioclavicular joint replacement prosthesis

[0037] 11 First end face

[0038] 12 Second end face

[0039] 13. First cavity

[0040] 2 Clavicle acromion connector

[0041] 21 First Coverage

[0042] 3 Scapula Infraspinous Fossa Connector Connector

[0043] 31 Second coverage

[0044] 4 First screw hole

[0045] 5 Second screw hole

[0046] 6 Micropores

[0047] 7 Attachment holes DETAILED DESCRIPTION

[0048] The following is a description of the implementation of the present invention by means of specific embodiments. Those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification.

[0049] See also Figures 1 to 5 . It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings in this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the limiting conditions for the implementation of the present invention, so they have no substantial technical significance. Any modification of the structure, change in the proportional relationship, or adjustment of the size should still fall within the scope of the technical content disclosed by the present invention without affecting the effects and purposes that can be achieved by the present invention. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description, and are not used to limit the scope of the implementation of the present invention. Changes or adjustments in their relative relationships should also be regarded as the scope of the implementation of the present invention without substantially changing the technical content.

[0050] An acromioclavicular joint replacement prosthesis, such as Figures 1 to 4 As shown, it includes an acromioclavicular joint replacement prosthesis body 1, a clavicular acromion end connector 2 and a scapula infraspinous fossa connector 3, the acromioclavicular joint replacement prosthesis body 1 and the clavicular acromion end connector 2 are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body 1 and the scapula infraspinous fossa connector 3 are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body 1 is customized according to the patient's defective bone tissue, that is, the acromioclavicular joint replacement prosthesis body 1 is in the shape of the defective acromioclavicular joint bone tissue, and is completely matched with the patient's defective acromioclavicular joint bone tissue.

[0051] In a preferred embodiment, the acromioclavicular joint replacement prosthesis body 1 is provided with a first cavity 13 matching the medullary cavity of the scapula osteotomy surface, and the acromioclavicular joint replacement prosthesis body 1 is concave inward at the end of the connector 3 near the infraspinous fossa of the scapula to form the first cavity 13.

[0052] In a preferred embodiment, the acromioclavicular joint replacement prosthesis body 1 is respectively provided with a first end face 11 and a second end face 12 at the clavicle acromion end connector 2 end and the scapula infraspinous fossa connector 3 end, the clavicle acromion end connector 2 is provided with a first covering surface 21, the first covering surface 21 faces the clavicle acromion end, the scapula infraspinous fossa connector 3 is provided with a second covering surface 31, the second covering surface 31 faces the scapula infraspinous fossa, the first end face 11 is smoothly connected to the first covering surface 21, and the second end face 12 is smoothly connected to the second covering surface 31.

[0053] In a preferred embodiment, it further comprises a plurality of first screw holes 4, wherein the first screw holes 4 penetrate through the clavicle acromion end connector 2, and the first screw holes 4 are used to fix the acromioclavicular joint replacement prosthesis to the clavicle acromion end via screws.

[0054] In a preferred embodiment, it also includes a plurality of second screw holes 5, which penetrate through the infraspinous fossa connector 3, and are used to fix the acromioclavicular joint replacement prosthesis to the infraspinous fossa via screws.

[0055] In a preferred embodiment, Figure 5 As shown, the first end surface 11, the second end surface 12, the first covering surface 21 and the second covering surface 31 are a layered structure of several layers, each layer of the layered structure has a plurality of micropores, and the micropores of the layers are interconnected.

[0056] In a preferred embodiment, at least one of the following technical features is also included:

[0057] 1) The pore diameters of the micropores 6 of the first end surface 11, the second end surface 12, the first covering surface 21 and the second covering surface 31 are 600 μm to 800 μm;

[0058] 2) The porosity of the first end surface 11, the second end surface 12, the first covering surface 21 and the second covering surface 31 is 60% to 80%; the porosity refers to the percentage of the pore volume to the total volume in the natural state, for example, the porosity of the first end surface refers to the percentage of the pore volume of the first end surface to the total volume of the first end surface in the natural state;

[0059] 3) The first end surface 11, the second end surface 12, the first covering surface 21 and the second covering surface 31 have a thickness of 1.5 mm to 2.0 mm.

[0060] In a preferred embodiment, it also includes a plurality of attachment holes 7 for muscle and ligament ending points, wherein the attachment holes 7 pass through the acromioclavicular joint replacement prosthesis body 1, and the attachment holes 7 are used for sutures to reattach the free muscle and ligament to the acromioclavicular joint replacement prosthesis body 1.

[0061] The second aspect of the present invention provides a method for preparing the acromioclavicular joint replacement prosthesis, comprising the following steps:

[0062] 1) Obtain a model of the acromioclavicular joint, such as a computer aided design model (CAD model);

[0063] 2) Reverse modeling the model obtained in step 1) to obtain an acromioclavicular joint replacement prosthesis model; the model is roughly "C" shaped;

[0064] 3) Perform 3D printing based on the repair device model.

[0065] In a preferred embodiment, the steps include:

[0066] 1) Obtain acromioclavicular joint model through CT and MRI;

[0067] 2) performing three-dimensional registration and fusion on the model obtained in step 1), and then reverse modeling to obtain an acromioclavicular joint replacement prosthesis model;

[0068] Bones can be observed by CT, and soft tissues can be observed by MRI. The models obtained by the two can be 3D registered and fused to achieve a 3D reconstruction model that includes both bones and soft tissues. Then, reverse modeling can be achieved by existing software, such as E3D. The model after 3D registration and fusion and the model of the acromioclavicular joint as a whole constitute a normal acromioclavicular joint model. The reverse model establishes an acromioclavicular joint replacement prosthesis model based on the normal acromioclavicular joint model and the model after 3D registration and fusion.

[0069] 3) Perform 3D printing based on the repair device model.

[0070] Taking a patient's acromioclavicular joint replacement prosthesis as an example, when using the acromioclavicular joint replacement prosthesis, Figure 3 and Figure 4As shown, the acromioclavicular joint replacement prosthesis includes an acromioclavicular joint replacement prosthesis body 1, a clavicular acromion end connector 2 and a scapula infraspinous fossa connector 3, the acromioclavicular joint replacement prosthesis body 1 and the clavicular acromion end connector 2 are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body 1 and the scapula infraspinous fossa connector 3 are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body 1 is customized according to the defective bone tissue of the patient; the acromioclavicular joint replacement prosthesis also includes a plurality of attachment holes 7 for muscle ligament attachment points, and the acromioclavicular joint replacement prosthesis body 1 is provided with a bone connection for the scapula osteotomy surface The acromioclavicular joint replacement prosthesis body 1 is concave inward at the end of the connector 3 near the scapula infraspinous fossa to form the first cavity 13; the acromioclavicular joint replacement prosthesis body 1 is respectively provided with a first end face 11 and a second end face 12 at the end of the clavicle acromion end connector 2 and the end near the scapula infraspinous fossa connector 3, the clavicle acromion end connector 2 is provided with a first covering surface 21, the first covering surface 21 faces the clavicle acromion end, the scapula infraspinous fossa connector 3 is provided with a second covering surface 31, the second covering surface 31 faces the scapula infraspinous fossa, the first The end face 11 is smoothly connected to the first covering surface 21, and the second end face 12 is smoothly connected to the second covering surface 31. The first end face 11, the second end face 12, the first covering surface 21 and the second covering surface 31 are layered structures of several layers, each layer of the layered structure has a plurality of micropores, and the micropores of the layers are interconnected. The pore diameter of the micropores 6 of the first end face 11, the second end face 12, the first covering surface 21 and the second covering surface 31 is 600 μm to 800 μm, the porosity is 60% to 80%, and the thickness is is 1.5mm~2.0mm; the acromioclavicular joint replacement prosthesis also includes a plurality of first screw holes 4 and a plurality of second screw holes 5, the first screw holes 4 penetrate the clavicle acromion end connector 2, and the first screw holes 4 are used to fix the acromioclavicular joint replacement prosthesis to the clavicle acromion end via screws, the second screw holes 5 penetrate the scapula infraspinous fossa connector 3, and the second screw holes 5 are used to fix the acromioclavicular joint replacement prosthesis to the scapula infraspinous fossa via screws. During the initial implantation, the initial fixation can be performed by orthopedic screws to prevent the prosthesis from shifting.

[0071] The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Anyone familiar with the art may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by a person of ordinary skill in the art without departing from the spirit and technical concept disclosed by the present invention shall still be covered by the claims of the present invention.

Claims

1. A acromioclavicular joint replacement prosthesis, characterized in that: The invention comprises an acromioclavicular joint replacement prosthesis body (1), a clavicular acromion end connecting piece (2) and a scapula infraspinous fossa connecting piece (3), wherein the acromioclavicular joint replacement prosthesis body (1) and the clavicular acromion end connecting piece (2) are smoothly transitionally connected, the acromioclavicular joint replacement prosthesis body (1) and the scapula infraspinous fossa connecting piece (3) are smoothly transitionally connected, and the acromioclavicular joint replacement prosthesis body (1) is customized according to the defective bone tissue of the patient; The acromioclavicular joint replacement prosthesis body (1) is provided with a first cavity (13) matching the bone marrow cavity of the scapula osteotomy surface, and the acromioclavicular joint replacement prosthesis body (1) is concave inward at the end of the connector (3) near the infraspinous fossa of the scapula to form the first cavity (13); the acromioclavicular joint replacement prosthesis also includes a plurality of attachment holes (7) for muscle and ligament attachment points, and the attachment holes (7) pass through the acromioclavicular joint replacement prosthesis body (1); The acromioclavicular joint replacement prosthesis body (1) is provided with a first end face (11) and a second end face (12) at the end of the clavicle acromion end connector (2) and the end of the proximal scapula infraspinous fossa connector (3), respectively; the clavicle acromion end connector (2) is provided with a first covering surface (21), the first covering surface (21) faces the clavicle acromion end; the scapula infraspinous fossa connector (3) is provided with a second covering surface (31), the second covering surface (31) faces the scapula infraspinous fossa; the first end face (11) is connected to the first covering surface (21) in a smooth transition, and the second end face (12) is connected to the second covering surface (31) in a smooth transition; the first end face (11), the second end face (12), the first covering surface (21) and the second covering surface (31) are a layered structure of several layers, each layer of the layered structure has a plurality of micropores, and the micropores of the layers are interconnected.

2. The acromioclavicular joint replacement prosthesis according to claim 1, characterized in that: It also includes a plurality of first screw holes (4), which penetrate the clavicle acromion end connector (2), and are used to fix the acromioclavicular joint replacement prosthesis to the clavicle acromion end via screws.

3. The acromioclavicular joint replacement prosthesis according to claim 1, characterized in that: It also includes a plurality of second screw holes (5), which penetrate the scapula infraspinous fossa connecting piece (3), and are used to fix the acromioclavicular joint replacement prosthesis with the scapula infraspinous fossa via screws.

4. The acromioclavicular joint replacement prosthesis according to claim 1, characterized in that: It also includes at least one of the following technical features: a) the pore diameters of the micropores (6) of the first end surface (11), the second end surface (12), the first covering surface (21) and the second covering surface (31) are 600 μm to 800 μm; b) the porosity of the first end surface (11), the second end surface (12), the first covering surface (21) and the second covering surface (31) is 60% to 80%; c) The first end surface (11), the second end surface (12), the first covering surface (21) and the second covering surface (31) have a thickness of 1.5 mm to 2.0 mm.

5. The method for preparing the acromioclavicular joint replacement prosthesis according to any one of claims 1 to 4, characterized in that: The steps include: a) Obtain a model of the acromioclavicular joint; b) reverse modeling the model obtained in step 1) to obtain an acromioclavicular joint replacement prosthesis model; c) Perform 3D printing based on the repair device model.

6. The preparation method according to claim 5, characterized in that: The steps include: a) Obtain acromioclavicular joint model through CT and MRI; b) performing three-dimensional registration and fusion on the model obtained in step 1), and then reverse modeling to obtain an acromioclavicular joint replacement prosthesis model; c) Perform 3D printing based on the repair device model.

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