A fully automatic thrombus elasticity detection device and detection method

Abstract

The present invention discloses a fully automatic thrombus elasticity detection device and detection method, the device includes a control device, and a detection cup carrying device connected to the control device, a detection drive device, multiple detection channels, a reagent storage device, a blood sample carrying device and a liquid adding device, the detection drive device includes a cup clamping mechanism and a detection drive mechanism connected to the cup clamping mechanism, the cup clamping mechanism is driven by the detection drive mechanism to move to the detection cup carrying device, each detection channel, and the liquid adding device respectively, at least automatically taking the cup, and cooperating with the process of removing the cup cover, adding reagents and blood samples, and blood testing. The present invention realizes full automation in the blood coagulation data detection process through the cooperation of two manipulators and the integration of each device into a chassis, thereby improving the detection efficiency and detection accuracy.

Description

Technical Field

[0001] The present invention relates to a thromboelastograph, and in particular to a fully automatic thrombus elasticity detection device and detection method. Background Art

[0002] A thromboelastometer is a medical device used to detect whether the blood can coagulate normally. Before surgery, it is generally necessary to test the patient's blood coagulation data with a thromboelastometer. The detected blood coagulation data is used to determine whether the patient's blood coagulation process is normal. Surgery can only be performed on the patient if the blood can coagulate normally. If there is an abnormality in the blood coagulation process, the patient's blood will not be able to coagulate normally during the operation, resulting in difficulty in stopping bleeding, which may endanger the patient's life.

[0003] The physical properties of the blood clot are detected based on the following principle: a special cylindrical blood cup containing blood is rotated at a low speed at an angle of 4.75, and the movement of the blood sample is detected by a detection rod immersed in the blood sample. After the fibrin platelet complex sticks the cup and the detection rod together, the rotational force generated by the rotation of the cup can be transmitted to the detection rod in the blood sample. The strength of the fibrin platelet complex can affect the amplitude of the detection rod movement, so that a strong blood clot can cause the movement of the needle to synchronize with the movement of the cup. Therefore, the amplitude of the movement of the measuring rod is directly related to the strength of the formed blood clot. When the blood clot retracts or dissolves, the connection between the detection rod and the blood clot is released, the movement of the cup is no longer transmitted to the detection rod, and the rotation of the detection rod is detected by the sensor.

[0004] The current thromboelastography instrument has a low degree of automation when testing blood coagulation data, and requires manual processes such as taking the cup, filling the cup, adding blood and reagents to the test cup, and unloading the cup. This requires a lot of time from the tester, resulting in high labor intensity in testing blood coagulation data and low testing efficiency. Summary of the invention

[0005] The purpose of the present invention is to overcome the defects of the prior art and provide a fully automatic thrombus elasticity detection device and detection method.

[0006] To achieve the above-mentioned purpose, the present invention proposes the following technical solution: a fully automatic thrombus elasticity detection device, comprising a control device, a detection cup carrying device connected to the control device, a detection drive device, a plurality of detection channels, a reagent storage device, a blood sample carrying device and a liquid adding device, wherein:

[0007] The testing cup carrying device carries a plurality of testing cups required for testing;

[0008] The detection drive device includes a cup clamping mechanism and a detection drive mechanism connected to the cup clamping mechanism. The cup clamping mechanism is driven by the detection drive mechanism to move to the detection cup carrying device, each detection channel, and the liquid adding device, and at least automatically takes the cup, and cooperates with the process of removing the cup cover, adding reagents and blood samples, and blood testing;

[0009] The detection channel is used to automatically complete the blood detection process;

[0010] The reagent storage device carries a plurality of reagent tubes, each of which contains a reagent;

[0011] The blood sample carrying device carries a plurality of blood sample test tubes, each of which contains a type of blood sample;

[0012] The liquid adding device moves to the reagent storage device and the blood sample carrying device respectively, extracts the reagent and the blood sample respectively, and adds the extracted reagent and the blood sample into the detection cup respectively.

[0013] Preferably, the detection cup carrying device comprises a detection cup tray and a first rotating disk, the detection cup tray is mounted on the first rotating disk, and carries a plurality of detection cups thereon.

[0014] Preferably, the detection drive mechanism includes a first lifting drive mechanism, a rotation drive mechanism and a horizontal drive mechanism all connected to the cup clamping mechanism. The cup clamping mechanism is driven by the first lifting, rotation and horizontal drive mechanisms to move to the detection cup carrying device, each detection channel and the liquid adding device respectively.

[0015] Preferably, the liquid adding device includes a liquid circuit system and a blood extraction drive mechanism, a reagent extraction drive mechanism and a rotation drive mechanism connected to the liquid circuit system; the blood extraction drive mechanism is connected to the blood suction member to drive the blood suction member to extend into or out of the blood sample tube; the reagent extraction drive mechanism is connected to the reagent suction member to drive the reagent suction member to extend into or out of the reagent tube; the rotation drive mechanism is connected to both the blood extraction drive mechanism and the reagent extraction drive mechanism, and is used to drive the two to move to the reagent storage device and the blood sample carrying device respectively.

[0016] Preferably, the reagent storage device comprises a shell, a conductive base installed in the shell, a conductive drawer for placing reagents, and an interlocking mechanism for pressing the conductive drawer and the conductive base to lock or unlock the conductive drawer, and the conductive drawer is movably installed on the conductive base.

[0017] Preferably, the blood sample carrying device comprises a second rotating disk and a blood sample tray mounted on the second rotating disk, and the blood sample tray carries a plurality of blood sample tubes.

[0018] Preferably, the thrombus elasticity detection device further comprises a waste collection device for collecting the used detection cups transferred by the detection drive device.

[0019] Preferably, the control device, the detection cup carrying device, the detection drive device, the multiple detection channels, the reagent storage device, the blood sample carrying device and the liquid adding device are all integrated in an outer cover.

[0020] Preferably, the detection channel includes a cup cover device, a rotating mechanism connected to the detection cup, and a second lifting drive mechanism, the cup cover device is used to unload the cup cover from the detection rod into the detection cup, the second rotating mechanism is used to control the rotational movement of the detection cup during detection, and the second lifting drive mechanism is used to lift the detection cup to a set height.

[0021] The present invention also discloses another technical solution: a fully automatic thrombus elasticity detection method, comprising:

[0022] S1, filling the test cup carrying device with test cups;

[0023] S2, the cup clamping mechanism of the detection driving device is driven by the detection driving mechanism to first move to the detection cup carrying device to remove the detection cup, and then move the clamped detection cup to the detection channel to cover it, and then move the detection cup without the cup cover to the reagent storage device and the blood sample carrying device to add reagents and blood samples to the detection cup respectively, and after adding, move the detection cup and load it onto the detection channel;

[0024] S3, the detection channel performs blood coagulation data detection;

[0025] S4, after the detection is completed, the detection drive device removes the detection cup from the detection channel;

[0026] S5, after the detection is completed, the cup clamping mechanism is driven by the detection driving mechanism to unload the detection cup onto the waste collection device;

[0027] S6, repeat the above steps S1 to S5.

[0028] The beneficial effects of the present invention are as follows: the present invention realizes full automation of the blood coagulation data detection process and improves detection efficiency and detection accuracy through the cooperation of two manipulators (a detection drive device and a liquid adding device) and the integration of a detection cup carrying device, a detection channel, a reagent storage device, a blood sample carrying device, etc. into one chassis. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention after the outer cover is assembled;

[0030] Figure 2 , Figure 3It is a schematic diagram of the three-dimensional structure at two angles after removing the outer cover of the present invention;

[0031] Figure 4 It is a schematic diagram of the three-dimensional structure of the detection cup carrying device of the present invention;

[0032] Figure 5 yes Figure 4 Schematic diagram of the explosion structure;

[0033] Figure 6 It is a schematic diagram of the three-dimensional structure of the detection cup tray of the present invention when viewed from above;

[0034] Figure 7 is a schematic diagram of the top view of the structure of the first rotating disk;

[0035] Figure 8 It is a three-dimensional structural schematic diagram of the present invention (excluding the rotation drive mechanism);

[0036] Fig. 9 It is a schematic diagram of the overall three-dimensional mechanism of the present invention except for the horizontal driving mechanism;

[0037] Fig.10 yes Fig. 9 A schematic diagram of a top view structure;

[0038] Fig.11 It is a schematic diagram of the three-dimensional structure of the detection channel (without the heat preservation cover) of the present invention;

[0039] Fig.12 yes Fig.11 A schematic diagram of the enlarged structure of the circled part;

[0040] Fig.13 It is a schematic diagram of the three-dimensional structure of the detection channel of the present invention from another angle;

[0041] Fig.14 is a three-dimensional schematic diagram of a reagent storage device of the present invention;

[0042] Fig.15 is a schematic cross-sectional view of a reagent storage device of the present invention;

[0043] Fig.16 is a three-dimensional schematic diagram of a conductive base of the present invention;

[0044] Fig.17 is a three-dimensional schematic diagram of a conduction drawer of the present invention;

[0045] Fig.18 yes Fig.17 Schematic diagram from top view;

[0046] Fig.19 It is a three-dimensional schematic diagram of the refrigeration mechanism of the present invention;

[0047] Fig. 20 is a schematic front view of the blood sample carrying device of the present invention;

[0048] Fig.21 yes Fig. 20 A three-dimensional schematic diagram of the rotating disk;

[0049] Fig. 22 yes Fig. 20 A three-dimensional schematic diagram of a blood sample tray;

[0050] Fig.23 yes Fig. 22 A bottom view of the middle tray body;

[0051] Fig.24 yes Fig. 20 A three-dimensional schematic diagram of the transmission mechanism;

[0052] Fig.25 It is a structural block diagram of the liquid circuit system of the present invention;

[0053] Figure 26 to Figure 28 All of them are structural block diagrams of different embodiments of the blood sample fluid path system of the present invention;

[0054] Fig.29 It is a structural block diagram of the reagent liquid path system of the present invention;

[0055] Fig.30 It is a schematic diagram of the three-dimensional structure of the liquid taking device of the present invention;

[0056] Fig.31 yes Fig.30 Schematic diagram of the enlarged structure of the circled part.

[0057] Reference numerals:

[0058] 100. Control device;

[0059] 200, detection cup carrying device, 201, detection cup tray, 202, first rotating disk, 203, rotating disk driving device, 204, support frame, 205, carrying part, 206, first matching mounting part / groove, 207, second matching mounting part, 209, first polygonal matching surface, 210, limiting part, 211, second polygonal matching surface, 212, cup hole, 213, first power source, 214, gear assembly, 215, motor shaft, 216, first master and slave wheels, 217, first driven wheel, 218, first sensor;

[0060] 300, detection drive device, 301, cup clamping mechanism, 302, first lifting drive mechanism, 303, rotation drive mechanism, 304, horizontal drive mechanism, 305, cup clamping mounting seat, 306, second drive source, 308, clamping jaw assembly, 309, reset elastic member, 310, clamping arm, 311, clamping arm, 312, second sensor, 313, mounting frame, 314, third drive source, 315, worm, 316, turbine, 317, screw, 318, lifting guide rod, 319, mounting plate, 320, fourth drive source, 321, rotating shaft, 322, fifth drive source, 323, driving screw, 324, slider;

[0061] 400, detection channel, 401, ninth driving source, 402, driving rod, 403, hitting plate, 404, punching, 405, detection rod, 406, guide rod, 407, cup cover, 408, heat preservation cover, 409, rotating mechanism, 410, second driving source, 411, cam, 412, rocker arm, 413, lifting driving mechanism, 414, motor, 415, screw rod, 416, cup holder, 417, slide, 418, bracket;

[0062] 500, reagent storage device, 501, shell, 502, conductive base, 503, conductive drawer, 504, refrigeration mechanism, 505, locking assembly, 506, rotating member, 507, first elastic member, 508, track groove, 509, locking pin, 510, opening, 511, first guide groove, 512, limit groove, 513, second guide groove, 514, yield groove, 515, second elastic member, 516, guide member, 517, accommodating groove, 518, guide rail, 519, slide groove, 520, drawer body, 521, conductive carrier, 522, drawer panel, 523, refrigeration member, 524, heat dissipation member, 525, fan, 526, air inlet, 527, rotating plate, 528, liquid extraction port;

[0063] 600, blood sample carrying device, 601, second rotating disk, 602, blood sample tray, 603, regular polygonal protrusion, 604, regular polygonal groove, 605, tray body, 606, carrier, 607, second opening, 608, fixing seat, 609, blood sample tube carrying seat, 610, transmission mechanism, 611, transmission shaft, 612, second driving wheel, 613, second driven wheel, 614, motor, 615, barcode reader, 616, plane light, 617, containing groove;

[0064] 700, outer cover;

[0065] 800, testing cup;

[0066] 900, liquid circuit system, 901, blood sample liquid circuit system, 902, reagent liquid circuit system, 903, blood suction member, 904, first suction control member, 905, suction member cleaning device, 906, first control valve, 907, air source, 908, water source, 909, one-way valve, 910, first diaphragm pump, 911, suction member outer wall cleaning device, 912, suction member cleaning pool, 913, second diaphragm pump, 914, sewage collection device, 915, third diaphragm pump, 916, sewage bucket, 917, sewage outlet, 918, reagent suction member, 919, second suction control member, 920, integrated rod, 921, connecting port, 922, water source inlet; 923, adapter;

[0067] 930. Liquid collection device, 931. Blood extraction drive mechanism, 932. Reagent extraction drive mechanism, 933. Rotation drive mechanism, 934. First screw rod, 935. First slide, 936. First mounting plate, 937. First gear, 938. Second gear, 939. Second mounting plate, 940. Rotation bearing, 941. First slide rail, 942. First fixed boss, 943. Seventh drive source, 944. Second screw rod, 945. Second slide, 946. Second slide rail, 947. Second fixed boss, 948. Base, 949. Eighth drive source, 950. Rotation shaft, 951. Third motor, 952. Liquid level sensor, 953. Waste collection, 954. Tenth drive source. DETAILED DESCRIPTION

[0068] The technical solutions of the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings of the present invention.

[0069] The present invention discloses a fully automatic thrombus elasticity detection device and detection method, which realizes the full automation of the processes of taking a cup, filling a cup, adding blood and reagents to the detection cup, detection, and unloading the cup after detection during the blood coagulation data detection process.

[0070] Combination Figure 1 to Figure 3 As shown, the fully automatic thrombus elasticity detection device disclosed in the present invention includes a control device 100, and a detection cup carrying device 200, a detection drive device 300, a plurality of detection channels 400, a reagent storage device 500, a blood sample carrying device 600 and a liquid adding device connected to the control device 100. In this embodiment, these devices are integrated in an outer cover 700. The detection drive device 300 and the liquid adding device in the outer cover 700 cooperate to completely replace manual labor and complete the full automation of the blood coagulation data detection process.

[0071] Specifically, combined Figures 4 to 7As shown, the test cup carrying device 200 is used to carry the test cups required in the blood coagulation test process. It specifically includes a test cup tray 201, a first rotating disk 202, a rotating disk driving device 203 and a support frame 204, wherein the test cup tray 201 and the first rotating disk 202 are matched by using polygonal matching surfaces with different sides and arranged in a multiple relationship, so that the test cup tray 201 can be quickly installed on the first rotating disk 202.

[0072] Specifically, the detection cup tray 201 is integrally formed and is disc-shaped as a whole. It specifically includes a plurality of load-bearing parts 205 arranged in layers from top to bottom, and the outer diameters of these load-bearing parts 205 increase in sequence from the inner side to the outer side of the detection cup tray 201, that is, the innermost and uppermost load-bearing part 205 has the smallest outer diameter, while the outermost and lowermost load-bearing part 205 has the largest outer diameter, so that a step is formed between two adjacent load-bearing parts 205. The layered design structure of the detection cup tray 201 allows the tray to carry more detection cups 800 as needed.

[0073] Each carrying portion 205 is provided with at least one circle of cup holes 212 evenly distributed along the circumferential direction for carrying the test cups, and the shape of the cup holes 212 is configured to match the shape of the test cups 800. In this embodiment, the entire test cup tray 201 can carry a total of 48 test cups 800.

[0074] The detection cup tray 201 is installed on the first rotating disk 202. The detection cup tray 201 and the first rotating disk 202 are installed in cooperation with each other through the first matching installation part 206 and the second matching installation part 207, so that the detection cup tray 201 can be quickly installed on the first rotating disk 202. Specifically, the first matching installation part 206 is formed on the lower surface of the detection cup tray 201, specifically located at the center of the lower surface, and is formed by being recessed upward from the lower surface of the detection cup tray 201, that is, forming a groove 208. And the inner side surface of the groove 208 is formed as a first polygonal matching surface 209. In this embodiment, the first polygonal matching surface 209 is a regular polygon, specifically a regular octagon.

[0075] The first rotating disk 202 specifically includes the above-mentioned second matching mounting portion 207 and the limiting portion 210. The second matching mounting portion 207 is formed by the upper surface of the limiting portion 210 protruding upward and extending. The second matching mounting portion 207 is inserted into the first matching mounting portion 206. After insertion, the outer side surface of the second matching mounting portion 207 is formed into a second polygonal matching surface 211, which matches with the first polygonal matching surface 209 of the first matching mounting portion 206. The second polygonal matching surface 211 is also a polygon, but the ratio of its number of sides to the number of sides of the first polygonal matching surface 209 is 1:n, wherein n is an integer greater than or equal to 2, that is, the number of sides of the two matching surfaces is different (not a 1:1 relationship) and is in a multiple relationship. In this embodiment, the second polygonal matching surface 211 is a 24 regular polygon, that is, the ratio of the number of sides of the first polygonal matching surface 209 and the second polygonal matching surface 211 is 1:4.

[0076] Of course, the first mating mounting portion 206 and the second mating mounting portion 207 are not limited to the above-mentioned structures of the matching grooves and protrusions, but can also be replaced by the first mating mounting portion 206 being a protrusion structure and the second mating mounting portion 207 being a groove structure, as long as the two can be matched with polygonal mating surfaces with different numbers of sides and arranged in a multiple relationship.

[0077] The rotating disk driving device 203 is connected to the first rotating disk 202, and is used to drive the first rotating disk 202 to rotate in the radial direction, so as to cooperate with the detection driving device on the thromboelastography instrument to sequentially grab the detection cup 800. In this embodiment, the rotating disk driving device 203 specifically includes a first power source 213, a gear assembly 214 and a drive shaft, wherein the first power source 213 can be a motor, and the gear assembly 214 is connected to the motor shaft 215 of the motor 213 and is connected to the first rotating disk 202, thereby driving the radial rotation of the first rotating disk 202. In this embodiment, the gear assembly 214 specifically includes a first master-slave wheel 216 and a first driven wheel 217, the driving wheel 210 is fixedly mounted on the motor shaft 215, the first driven wheel 217 is meshed with the driving wheel 210, and rotates with the motor shaft 215 as the rotation axis. The motor shaft 215 is connected to both the first driven wheel 217 and the first rotating disk 202 , and drives the first rotating disk 202 to rotate radially under the drive of the gear assembly 214 .

[0078] The support frame 204 is used to support and install the above-mentioned detection cup tray 201, the first rotating disk 202 and the rotating disk driving device 203.

[0079] Preferably, the detection cup carrying device of the present invention further includes at least one sensor 218 installed on the support frame 204, and the first sensor 218 is arranged close to the detection cup tray 201, and is used to detect whether there is a detection cup on the detection cup tray 201. In this embodiment, three first sensors 218 are arranged on the support frame 204, and are located below the detection cup tray 201. The three first sensors 218 are respectively arranged corresponding to the three circles of detection cups on the detection cup tray 201, that is, one first sensor 218 is arranged corresponding to each circle of detection cups 800.

[0080] The working principle of the detection cup carrying device is: manually or automatically fill the detection cup tray 201 with detection cups 800, and quickly install the detection cup tray 201 filled with detection cups 800 on the first rotating disk 202. The first rotating disk 202 rotates under the drive of the rotating disk driving device 203, and the detection cups 800 are transferred to the position to be grasped by the detection driving device (manipulator). While the first rotating disk 202 rotates, the first sensor 218 senses whether there are detection cups 800 in the corresponding cup holes 212 on the rotating disk. If it is detected that there are no detection cups 800 on the detection cup tray 201, the detection cup tray 201 is removed from the first rotating disk 202, and the detection cups 800 are refilled and the above process is repeated.

[0081] Combination Figure 8 to Figure 10 As shown, the detection drive device 300 is used to realize the automation of the actions of taking, loading and unloading cups during the blood coagulation data detection process. In this embodiment, the detection drive device specifically includes a cup clamping mechanism 301, a first lifting drive mechanism 302, a rotation drive mechanism 303 and a horizontal drive mechanism 304. The cup clamping mechanism 301, under the cooperative drive of the lifting, rotating and horizontal drive mechanisms 302, 303, 304, clamps and unloads the detection cup 800 to the above-mentioned detection cup carrying device 200, the detection channel 400, and the liquid adding device.

[0082] The cup clamping mechanism 301 is used to realize the clamping and unloading of the detection cup 800. In this embodiment, it specifically includes a cup clamping mount 305, a second driving source 306, a clamping jaw assembly 308 and a reset elastic member 309, wherein the second driving source 306 is fixed on the cup clamping mount 305 and moves back and forth in the horizontal direction, and an electromagnet can be used for implementation; the clamping jaw assembly 308 is installed on the cup clamping mount 305, and clamps or unloads the detection cup 800 under the action of the second driving source 306. In this embodiment, the clamping jaw assembly 308 includes two clamping arms 310 and 311, one end of the two clamping arms 310 and 311 intersects, and the other end forms a clamping jaw. The second driving source 306 is arranged near the intersecting end of the clamping jaw assembly 308, and moves toward the direction close to the clamping jaw assembly 308, and after abutting against the intersecting end of the clamping jaw assembly 308, drives the other end of the clamping jaw assembly 308 to open. The resetting elastic member 309 is disposed between the two clamping arms 310 and 311 at the other end of the clamping jaw assembly 308 to provide a resetting elastic force to bring the other ends of the two clamping arms 310 and 311 back and forth. During implementation, the resetting elastic member 309 can be a spring.

[0083] Preferably, the cup clamping mechanism 301 further comprises a second sensor 312 mounted on the cup clamping mounting base 305 and arranged close to the clamping jaw assembly 308 for detecting the state of the clamping jaw assembly 308 clamping the detection cup 800, such as whether the detection cup 800 is clamped.

[0084] The first lifting drive mechanism 302 is connected to the cup clamping mechanism 301, and is used to drive the cup clamping mechanism 301 to perform lifting movement in the vertical direction. The first lifting drive mechanism 302 specifically includes a mounting frame 313, an eighth driving source 949, a driving steering assembly, and a screw 317, wherein the eighth driving source 949 is fixedly mounted on the mounting frame 313 and connected to the driving steering assembly. During implementation, the eighth driving source 949 can also be a motor; the driving steering assembly is used to convert the axial rotation of the driving shaft of the eighth driving source 949 into radial rotation. In this embodiment, the driving steering assembly includes a worm 315 connected to the driving shaft of the eighth driving source 949 and a turbine 316 that meshes with the worm 315. The turbine 316 is sleeved on the screw 317 and is threadedly connected to the screw 317; the screw 317 is vertically installed on the mounting frame 313, and rotates in the horizontal direction under the drive of the turbine 316; the screw 317 is also connected to the cup clamping mounting seat 305 of the cup clamping mechanism 301, and a threaded connection can be adopted. When the screw 317 rotates, the cup clamping mounting seat 305 is driven to move up and down in the vertical direction, thereby synchronously driving the clamping jaw assembly 308 to move up and down in the vertical direction, and adjusting the detection cup 800 on the clamping jaw assembly 308 to the required height.

[0085] Preferably, the first lifting drive mechanism 302 also includes at least one lifting guide rod 318 vertically fixed on the mounting frame 313 for guiding, and the cup clamping mechanism 301 is connected to the lifting guide rod 318. Specifically, the cup clamping mounting seat 305 of the cup clamping mechanism 301 passes through the lifting guide rod 318 and performs vertical lifting movement along the lifting guide rod 318 under the drive of the screw 317.

[0086] In addition, in this embodiment, the first lifting drive mechanism 302 and the rotating drive mechanism 303 are both integrated and installed on the same mounting plate 319, wherein the first lifting drive mechanism 302 is fixed above the mounting plate 319, and the rotating drive mechanism 303 is fixed below the mounting plate 319.

[0087] The rotating drive mechanism 303 is connected to the cup clamping mechanism 301, specifically connected to the above-mentioned mounting plate 319, and is used to drive the entire first lifting drive mechanism 302 to rotate in a second direction perpendicular to the above-mentioned first direction through the mounting plate 319. The second direction here is the horizontal direction, and then synchronously drives the cup clamping mechanism 301 connected to the first lifting drive mechanism 302 to rotate in the horizontal direction, so that the cup clamping mechanism 301 rotates and moves to the desired position.

[0088] In this embodiment, the rotating drive mechanism 303 specifically includes an eighth drive source 949 and a rotating shaft 950 connected to the eighth drive source 949. During implementation, the eighth drive source 949 can also be a motor. The rotating shaft 950 is fixedly connected to the first lifting drive mechanism 302, specifically to the above-mentioned mounting plate 319. By driving the mounting plate 319 to rotate in the horizontal direction, the first lifting drive mechanism 302 fixed on the mounting plate 319 is driven, and then the first lifting drive mechanism 302 synchronously drives the cup clamping mechanism 301 connected thereto to rotate in the horizontal direction.

[0089] The horizontal driving mechanism 304 is connected to the cup clamping mechanism 301, and is specifically fixedly connected to the above-mentioned mounting plate 319, and is used to drive the cup clamping mechanism 301 to move horizontally in the above-mentioned second direction (i.e., horizontal direction). Specifically, in this embodiment, the horizontal driving mechanism 304 includes a fifth driving source 322, a driving screw 323, and a slider 324, wherein, during implementation, the fifth driving source 322 can also be a motor, the driving screw 323 is connected to the fifth driving source 322, the slider 324 is slidably mounted on the driving screw 323, and the upper end of the slider 324 is fixedly connected to the mounting plate 319, the driving screw 323 drives the slider 324 to move horizontally in the horizontal direction under the drive of the fifth driving source 322, and the slider 324 drives the rotating driving mechanism 303, the first lifting driving mechanism 302, and the cup clamping mechanism 301 integrated on the mounting plate 319 to slide in the horizontal direction as a whole, and drives the cup clamping mechanism 301 to the corresponding station in the horizontal direction.

[0090] Combination Figure 11 to Figure 13 As shown, the detection channel 400 is used to detect blood coagulation data. In this embodiment, 8 detection channels 400 are set, respectively located on both sides of the above-mentioned detection drive device 300, and 4 detection channels 400 are set on each side. Each detection channel 400 specifically includes a cup cover device, a rotating mechanism 409 and a lifting drive mechanism 413, wherein the cup cover device includes a ninth driving source 401, a driving rod 402 and a beating plate 403, wherein the ninth driving source 401 can be implemented by a motor; the driving rod 402 is vertically arranged, one end (here the upper end) of which is connected to the ninth driving source 401, and the other end is a free end, which rotates under the drive of the ninth driving source 401. In this embodiment, the driving rod 402 is a screw, that is, the outer surface is provided with an external thread.

[0091] The beating plate 403 is sleeved on the driving rod 402, and is arranged horizontally, that is, perpendicular to the driving rod 402. The inner surface of the beating plate 403 in contact with the screw rod 402 is provided with an internal thread (not shown) to achieve a threaded connection between the two, so that when the screw rod 402 rotates under the drive of the ninth driving source 401, the beating plate 403 can move up and down relative to the screw rod 402. In this embodiment, the beating plate 403 is a plate structure as a whole, and the other end thereof away from the screw rod 402 is sleeved outside the detection rod 405, and a through hole 404 is formed on the end for the detection rod 405 to pass through, but the detection rod 405 does not contact the through hole 404.

[0092] Preferably, in order to guide the up and down movement of the beating plate 403, the cup cover beating device of this embodiment also includes at least one vertically arranged guide rod 406, and the beating plate 403 is also mounted on the outside of the guide rod 406, and moves up and down along the guide rod 406 under the drive of the screw 402.

[0093] The other end of the beating plate 403 is located above the cup cover 407 on the detection rod 405, and the plane where it is located is parallel or approximately parallel to the plane where the cup cover 407 is located. In addition, in order to further improve the stability of the beating plate 403 hitting the cup cover 407, the bottom area of ​​the other end of the beating plate 403 in contact with the cup cover 407 is set to be greater than or equal to the area of ​​the upper surface of the cup cover 407, so that the beating plate 403 can completely cover the cup cover 407 when in contact with the cup cover 407. In this way, the driving rod 402, driven by the ninth driving source 401, drives the beating plate 403 to move in the direction close to the cup cover 407, so that the beating plate 403 contacts the cup cover 407 to unload the cup cover 407 from the detection rod 405. Compared with the previous lever driving structure, the cup beating action is more stable.

[0094] More preferably, a heat-insulating cover 408 is provided outside the detection rod 405 to wrap the upper end of the cup cover 407. The heat-insulating cover 408 surrounds the detection rod 405 without contacting the detection rod 405 and is connected to the beating plate 403, and is used for vertical guidance during the up and down movement of the beating plate 403, while also increasing the contact area with the cup cover 407.

[0095] The rotating mechanism 409 is used to control the rotation of the detection cup 800 during detection. In this embodiment, the rotating mechanism 409 specifically includes a second driving source 410, a cam 411 and a rocker arm 412. The second driving source 410 can also be implemented by a motor. The cam 411 is connected to the second driving source 410 and rotates under the drive of the second driving source 410. One end of the rocker arm 412 is in contact with the cam 411, and the other end is connected to the cup holder 416 for holding the detection cup 800. When working, the rocker arm 412 drives the cup holder 416 connected thereto to swing synchronously while the cam 411 rotates, thereby using the curve characteristics of the cam 411 to achieve precise control of the swing amplitude of the cup holder 416.

[0096] The lifting drive mechanism 413 is connected to the cup holder 416, and is used to drive the detection cup 800 in the cup holder 416 to move to the set detection height. When implemented, it may include a motor 414, a screw rod 415, a slide 417 and a bracket 418. The motor 414 is connected to the screw rod 415, the slide 417 is set on the screw rod 415, and the rotary drive mechanism 8 is connected to the slide 417. The screw rod 415 drives the slide 417 to move up and down under the drive of the motor 414, thereby driving the detection cup 800 to move up and down, which will not be described in detail here. In addition, the principle and structure of the detection channel 400 for blood coagulation data detection can refer to the existing ones, which will not be described in detail here.

[0097] Combination Figures 14 to 19 As shown, the reagent storage device 500 is used to refrigerate reagents and / or blood. In this embodiment, the reagents are refrigerated so that the liquid adding device can take the reagents for detection. It specifically includes a shell 501, a conductive base 502, a conductive drawer 503, an interlocking mechanism and a refrigeration mechanism 504. Among them, the conductive base 502 is installed in the shell 501, which is used for heat transfer; the conductive drawer 503 is located in the shell 501 and is movably installed on the conductive base 502, which is used to place the reagent; the refrigeration mechanism 504 is installed in the shell 501, which is used to generate a cold source; the interlocking mechanism is installed in the shell 501, which is used to achieve press-lock or press-unlock between the conductive drawer 503 and the conductive base 502.

[0098] In a specific implementation, the conduction drawer 503 and the conduction base 502 can be unlocked by pressing the conduction drawer 503 under the action of the interlocking mechanism, and then the conduction drawer 503 can be pulled out to place the reagent to be refrigerated in the conduction drawer 503; after the reagent is placed, the conduction drawer 503 is assembled onto the conduction base 502 and the conduction drawer 503 and the conduction base 502 are locked by pressing the conduction drawer 503 under the action of the interlocking mechanism, and the refrigeration mechanism 504 exchanges heat with the conduction drawer 503 through the conduction base 502, thereby cooling the reagent in the conduction drawer 503.

[0099] The interlocking mechanism includes a locking assembly 505 installed on the conductive base 502 and a track groove 508 installed on the conductive drawer 503. With the cooperation of the locking assembly 505 and the track groove 508, the conductive drawer 503 and the conductive base 502 can be pressed to lock or unlock.

[0100] Specifically, the locking assembly 505 includes a rotating member 506 and a first elastic member 507. One end of the rotating member 506 is pivotally connected to the conductive base 502 via a rotating shaft, and the opposite end is provided with a locking pin 509 extending into the track groove 508. Under the action of external force, the rotating member 506 can drive the locking pin 509 to rotate around the rotating shaft, and the first elastic member 507 is connected to the rotating member 506 to drive the rotating member 506 to reset.

[0101] In this embodiment, the first elastic member 507 is preferably a torsion spring.

[0102] The track groove 508 includes a first opening 510, a first guide groove 511, a limiting groove 512 and a second guide groove 513. One end of the limiting groove 512 is connected to one end of the first guide groove 511, and the opposite end is connected to one end of the second guide groove 513. The other end of the first guide groove 511 and the other end of the second guide groove 513 are both connected to the first opening 510. In this embodiment, it is best to have a depth of the first guide groove 511 greater than a depth of the second guide groove 513, so that the lock pin 509 can first enter the first guide groove 511 when entering through the first opening 510.

[0103] In a specific implementation, pressing the conduction drawer 503 can make the conduction drawer 503 slide on the conduction base 502. During the movement of the conduction drawer 503, the locking pin 509 enters the first guide groove 511 through the first opening 510, and enters the limiting groove 512 under the action of the first guide groove 511. Through the cooperation of the limiting groove 512 and the locking pin 509, the conduction drawer 503 and the conduction base 502 are locked. Further, the conduction drawer 503 is continued to be pressed. Under the action of the first elastic member 507, the locking pin 509 moves from the limiting groove 512 to the second guide groove 513. Under the action of the second guide groove 513, the locking pin 509 is finally moved out through the first opening 510, and the conduction drawer 503 and the conduction base 502 are unlocked.

[0104] In this embodiment, the limiting groove 512 is V-shaped or U-shaped as a whole, and the track groove 508 is heart-shaped as a whole.

[0105] The conductive base 502 is also provided with a clearance groove 514, and the locking assembly 505 is installed in the clearance groove 514. Of course, the clearance groove 514 can also be provided on the conductive drawer 503, and the track groove 508 can be provided in the clearance groove 514. In this embodiment, it is best to provide the clearance groove 514 for assembling the rotating assembly on the conductive base 502.

[0106] Furthermore, a second elastic member 515 for quickly popping out the conductive drawer 503 is provided on the conductive base 502. During implementation, when locked, the second elastic member 515 is continuously compressed during the sliding process of the conductive drawer 503 on the conductive base 502. When the conductive drawer 503 is locked with the conductive base 502, the conductive drawer 503 stops compressing the second elastic member 515. When unlocked, the conductive drawer 503 is pressed, and the conductive drawer 503 further compresses the second elastic member 515. When the locking pin 509 moves from the limiting groove 512 to the second guide groove 513, the second elastic member 515 generates a restoring force, so that the conductive drawer 503 pops out, which facilitates the conductive drawer 503 to be drawn out of the shell 501.

[0107] The conductive drawer 503 is also provided with a guide member 516 for enabling the locking pin 509 to quickly enter the track groove 508. In this embodiment, the guide member 516 is in a triangular shape as a whole.

[0108] Furthermore, a plurality of receiving grooves 517 for placing reagents are provided on the conduction drawer 503. In this embodiment, the receiving grooves 517 are preferably arranged in an arc shape, but of course, they can also be arranged according to actual needs.

[0109] Furthermore, guide rails 518 are provided on both sides of the conductive drawer 503, and a slide groove 519 matching the guide rails 518 is provided on the conductive base 502. Under the action of the guide rails 518 and the slide groove 519, the conductive drawer 503 can be quickly assembled to the conductive base 502, thereby improving assembly accuracy.

[0110] In this embodiment, the conductive drawer 503 adopts a split structure, which includes a drawer body 520 and a conductive carrier 521 installed on the drawer body 520. The conductive carrier 521 is in contact with the conductive base 502, and heat exchange is achieved between the two. Further, a plurality of the accommodating grooves 517 are provided on the conductive carrier 521. During implementation, the reagent is placed in the accommodating grooves 517 to achieve heat exchange with the conductive carrier 521.

[0111] Furthermore, it also includes a drawer panel 522 connected to the conductive drawer 503 , and the conductive drawer panel is used to pull out or push in the conductive drawer 503 .

[0112] The refrigeration mechanism 504 includes a refrigeration element 523, a heat sink 524 and a fan 525. The refrigeration element 523 is installed between the conductive base 502 and the heat sink 524, and the heat sink 524 is installed between the refrigeration element 523 and the fan 525. Furthermore, a plurality of air inlets 526 are provided at a position of the housing 501 close to the heat sink 524. Under the action of the fan 525, cooling air enters the housing 501 through the air inlets 526 and flows through the heat sink 524, taking away the heat on the heat sink 524.

[0113] Furthermore, the refrigeration mechanism also includes a mounting plate 527 for mounting the refrigeration component 523 .

[0114] During implementation, the refrigeration element 523 generates a cold source when powered on, and achieves heat exchange with the reagent through the conductive base 502 and the conductive carrier 521. The heat is transferred to the heat sink 524. The fan 525 inhales cooling air through the air inlet 526, and the cooling air takes away the heat from the heat sink 524.

[0115] The end of the housing 501 is also provided with a plurality of liquid taking ports 528 that match with the reagent bottles. During implementation, the liquid taking needle passes through the liquid taking port 528 and enters the reagent to absorb the reagent.

[0116] Combination Figure 20 to Figure 24As shown, the blood sample carrying device 600 is used to hold blood for the liquid adding device to take the blood sample for testing. It specifically includes a second rotating disk 601 and a blood sample tray 602 installed on the second rotating disk 601, and the blood sample tray 602 is used to carry a blood sample test tube containing a blood sample. In order to realize the rapid installation of the blood sample tray 602 on the second rotating disk 601, a regular polygonal protrusion 603 is provided on the second rotating disk 601, and a regular polygonal groove portion 604 is provided on the blood sample tray 602 to match the regular polygonal protrusion 603, and the ratio of the number of sides of the regular polygonal protrusion 603 to the regular polygonal groove portion 604 is at least 1:4, or a regular polygonal groove portion 604 is provided on the second rotating disk 601, and a regular polygonal protrusion 603 is provided on the blood sample tray 602 to match the regular polygonal groove portion 604, and the ratio of the number of sides of the regular polygonal protrusion 603 to the regular polygonal groove portion 604 is at least 1:4. By providing the regular polygonal protrusion 603 and the regular polygonal groove 604 , the blood sample tray 602 can be quickly assembled onto the second rotating disk 601 .

[0117] In this embodiment, it is best to set a regular hexagonal protrusion on the second rotating disk 601 and a regular icosagonal groove on the blood sample tray 602 .

[0118] Specifically, the blood sample tray 602 includes a tray body 605 and a plurality of carriers 606 mounted on the tray body 605, wherein a regular polygonal protrusion 603 or a regular polygonal groove 604 is arranged on the tray body 605, and the carriers 606 are used to place blood sample test tubes containing blood samples. The plurality of carriers 606 are distributed in a circle with the center of the tray body 605 as the center and enclose at least one circle. In specific implementation, it is best to enclose at least two circles with the plurality of carriers 606, and the carriers 606 located in the inner circle are staggered with the carriers 606 located in the outer circle, so as to facilitate the acquisition of the barcodes of the blood sample test tubes on the carriers 606 located in the inner circle.

[0119] Furthermore, a second opening 607 is provided on the carrier 606. During implementation, after the blood sample tube is placed on the carrier 606, the barcode on the blood sample tube is located at the second opening 607, so as to facilitate acquisition of the barcode on the blood sample tube.

[0120] The carrier 606 includes a cylindrical fixing seat 608 and a blood sample tube support seat 609 plugged into the fixing seat 608. The fixing seat 608 is mounted on the tray body 605, and the second opening 607 is disposed on the side periphery of the blood sample tube support seat 609. In this embodiment, the carrier 606 adopts a split design to facilitate the installation of the blood sample tube. Of course, the carrier 606 may also adopt an integrated design.

[0121] Furthermore, a receiving groove 617 for receiving the fixing seat 608 is provided on the tray body 605 . During implementation, the plurality of fixing seats 608 are distributed in a circle with the center of the tray body 605 as the center and surround at least one circle.

[0122] The blood sample carrier 600 further includes a transmission mechanism 610 for driving the second rotating disk 601 to rotate, which includes a transmission shaft 611, a second driving wheel 612, a second driven wheel 613 and a motor 614, wherein the second rotating disk 601 is mounted on one end of the transmission shaft 611, and the second driven wheel 612 is mounted on the opposite end, and the second driving wheel 612 is connected to the rotating shaft of the motor 614 and meshes with the second driven wheel 612. During implementation, the motor 614 drives the second driving wheel 612 to rotate, and the second driving wheel 612 then drives the second driven wheel 612 to rotate, and the second driven wheel 612 drives the second rotating disk 601 to rotate through the transmission shaft 611.

[0123] Furthermore, the blood sample carrier device further includes a barcode reader 615, which is disposed near the blood sample tray 602 and is used to read the barcode on the blood sample test tube. During implementation, the light emitted by the barcode reader 615 is a plane light 616. Since the carriers 606 of the outer circle and the carriers 606 of the inner circle are arranged in a staggered manner, the plane light 616 emitted by the barcode reader 615 can pass through the gaps between the carriers 606 of the outer circle and enter the inner circle, and then the barcode reader 615 can read the barcode of the blood sample test tube on the carrier 606 of the inner circle.

[0124] The liquid adding device is used to automatically add reagents and blood samples to the test cup. In this embodiment, the liquid adding device is used to automatically add reagents and blood samples to the test cup. Figure 25 to Figure 29 As shown, it specifically includes a liquid circuit system 900 and a liquid collecting device 930 connected to the liquid circuit system 900, wherein the liquid circuit system 900 includes an independent blood sample liquid circuit system 901 and a reagent liquid circuit system 902, wherein the blood sample liquid circuit system 901 is used to realize the automatic addition process of blood in the coagulation data detection, and the reagent liquid circuit system 902 is used to realize the actual automatic addition process in the coagulation data detection.

[0125] Specifically, in this embodiment, the blood sample liquid path system 901 includes a blood suction piece 903, a first suction control piece 904 and a suction piece cleaning device 905, wherein the blood suction piece 903 is used to suck blood, and is in the shape of a hollow suction needle as a whole, and when sucking blood, its lower end penetrates into the blood sample tube.

[0126] The first suction control component 904 is connected to the blood suction component 903, specifically connected to the upper end of the blood suction component 903 through a hose. During implementation, the first suction control component 904 can use a plunger pump, and its working principle is that when the first suction control component 904 is working, it controls the formation of negative pressure in the blood suction component 903, and draws the blood in the blood sample tube into the blood suction component 903. When it is closed, it controls the blood sucked by the blood suction component 903 to be released into the detection cup 800.

[0127] The suction piece cleaning device 905 is connected to the blood suction piece 903, and is used to thoroughly clean the inner wall of the blood suction piece 903 after the blood suction piece 903 releases blood into the detection cup. Specifically, in this embodiment, the suction piece cleaning device 905 includes a first control valve 906, and the first control valve 906 is connected to the blood suction piece 903 through the first suction control piece 904, and the first control valve 906 is also connected to the air source and the water source. During implementation, the first control valve 906 can adopt a control valve with at least three interfaces, such as a three-way valve, and of course it can also be a four-way valve, a five-way valve, etc. One of the interfaces of the three-way valve is connected to the first suction control piece 904, and the other two interfaces are connected to the air source 907 and the water source 908 respectively. During implementation, the water source 908 can be clean water, which is stored in a water tank, that is, the three-way valve is connected to the water tank; the air source 907 can be air; in addition, the first liquid circuit valve 906 and the water source 908 can also be connected through a adapter 923.

[0128] During cleaning, first, the three-way valve 906 controls the interface connected to the water tank 908 to be in a connected state, and the interface connected to the air source 907 to be in a closed state. Then, under the control of the first suction control component 904, the upper water source is sucked from the water tank 908 through each connecting hose into the blood suction component 903 to clean the inner wall of the blood suction component 903. After the cleaning is completed, in order to remove the residual cleaning liquid on the inner wall of the blood suction component 903, the three-way valve 906 controls the interface connected to the water tank 908 to be in a closed state, and the interface connected to the air source 907 to be in a connected state. Then, under the control of the first suction control component 904, the air source 907 is sucked into the blood suction component 903 through each connecting hose to blow away the residual cleaning liquid on the inner wall of the blood suction component 903. In this way, the blood suction component 903 is deeply cleaned and blown dry, so that it can suck other types of blood samples and avoid cross contamination between different blood samples.

[0129] Preferably, in order to prevent blood from flowing into the water tank 908 or the air source 907 through the first suction control member 904, or to prevent the backflow of the water source 908 and the air source 907, a one-way valve 909 may be further provided between the first suction control member 904 and the first control valve 906, i.e., the water source 908 and the air source 907 can be limited to be input into the blood suction member 903 in one direction, and the reverse direction is not connected. The one-way valve 909 is closed when the first suction control member 904 is turned on to control the blood suction member 903 to suction blood, and is opened when the suction member cleaning device 905 is working.

[0130] More preferably, a first diaphragm pump 910 is connected between the one-way valve 909 and the first control valve 906 to cooperate with the first suction control component 904 to realize suction control of the water source 908 and the air source 907 .

[0131] Furthermore, in order to clean the outer wall of the blood suction piece while cleaning the inner wall of the blood suction piece, the blood sample liquid path system 901 of the embodiment of the present invention also includes a suction piece outer wall cleaning device 911, which specifically includes a suction piece cleaning pool 912 and a second diaphragm pump 913, wherein the blood suction piece 903 extends into the suction piece cleaning pool 912, and the suction piece cleaning pool 912 is connected to the above-mentioned water source (i.e., the water tank 908) through the second diaphragm pump 913, that is, the second diaphragm pump 913 connects the suction piece cleaning pool 912 and the water tank 908, and is used to control the water in the water tank 908 to be sucked into the suction piece cleaning pool 912, so as to clean the outer wall of the blood suction piece 903 in the suction piece cleaning pool 912.

[0132] Specifically, a water source inlet 922 is provided on the side wall of the suction member cleaning tank 912 near the top thereof, and the water source inlet 922 is connected to the second diaphragm pump 913. Preferably, in order to ensure that the blood stained on the outer wall of the blood suction member 903 during blood suction can be cleaned, the height of the water source inlet 922 in the suction member cleaning tank 912 is set higher than the height of the blood sample on the outer wall of the blood suction member 903 extending into the suction member cleaning tank 912, that is, it is located above the blood sample on the outer wall of the blood suction member 903, so that the water entering the blood suction member 903 can completely cover the blood sample cleaned on the outer wall of the blood suction member 903, so that the blood sample on the outer wall of the blood suction member 903 is thoroughly cleaned.

[0133] Furthermore, the blood sample liquid path system of the embodiment of the present invention may also include a sewage collection device 914, which is connected to the above-mentioned suction member cleaning tank 912, and is used to collect and discharge the sewage generated after the suction member cleaning device 905 and the suction member outer wall cleaning device 911 are cleaned. Specifically, in this embodiment, the sewage collection device 914 includes a third diaphragm pump 915 and a sewage bucket 916 connected to the third diaphragm pump 915, wherein a sewage outlet 917 is provided on the suction member cleaning tank 912, specifically at the bottom thereof; the third diaphragm pump 915 is connected to the sewage outlet 917 and the sewage bucket 916, and is used to control the discharge and collection of the cleaning sewage generated in the suction member cleaning tank 912 into the sewage bucket 916.

[0134] In this embodiment, the reagent liquid path system 902 specifically includes at least one reagent suction piece 918 and a second suction control piece 919 connected to the reagent suction piece 918, wherein the reagent suction piece 918 is used to absorb the reagent required for the test. When the reagent suction piece 918 is implemented, it is generally set to multiple, and each reagent suction piece 918 corresponds to sucking a reagent. In this embodiment, 7 reagent suction pieces 918 are set, that is, corresponding to sucking 7 kinds of reagents. Of course, the number of reagent suction pieces 918 is not limited and can be set according to the reagent needs. Each reagent suction piece 918 is also a hollow suction needle shape as a whole. When sucking the reagent, its lower end goes deep into the reagent tube (not shown). And the 7 reagent suction pieces 918 are all connected to an integrated rod 92020, and a connecting port 921 is set at the position corresponding to each reagent suction piece 918 on the integrated rod 92020.

[0135] The second suction control member 919 is selectively connected to the communication port 921 on the integrated rod 92020 as required, so as to be connected to the reagent suction member 918 corresponding to the communication port 921. Because each reagent suction member 918 absorbs a detection reagent corresponding to each other, there will be no cross contamination between them, so the reagent liquid path system here does not need to be provided with a corresponding cleaning device.

[0136] The liquid collection device 930 realizes the automation of the blood sample and reagent adding process by cooperating with three designed driving mechanisms (blood extraction driving mechanism 931, reagent extraction driving mechanism 932 and rotation driving mechanism 933).

[0137] Combination Figure 30-31As shown, a liquid extraction device 930 disclosed in an embodiment of the present invention includes a blood extraction drive mechanism 931, a reagent extraction drive mechanism 932 and a rotation drive mechanism 933, wherein the blood extraction drive mechanism 931 is connected to the above-mentioned blood suction member 903, driving the blood suction member 903 to extend into or out of the blood sample test tube; the reagent extraction drive mechanism 932 is connected to the reagent suction member 918, driving the reagent suction member 918 to extend into or out of the reagent tube (not shown); the rotation drive mechanism 933 is connected to both the blood extraction drive mechanism 931 and the reagent extraction drive mechanism 932, and cooperates with these two mechanisms 1 and 2 to drive the two to rotate in the first direction, and move to the corresponding blood sample carrier 600 and reagent storage device 500 respectively. The first direction in this embodiment is the horizontal direction.

[0138] Specifically, the blood extraction drive mechanism 931 includes a sixth drive source 934, a first gear assembly, a first screw rod 934 and a first slide 935, wherein the sixth drive source 934 is fixed on a vertically arranged first mounting plate 936, specifically fixed to the lower end of the first mounting plate 936. During implementation, the sixth drive source 934 can adopt a first motor 937, and the drive shaft of the first motor 937 horizontally passes through the first mounting plate 936.

[0139] The first gear assembly includes a first gear 937 and a second gear 938, wherein the first gear 937 is fixed to the top end of the drive shaft of the first motor 937 (i.e., the end passing through the first mounting plate 936), and rotates axially under the drive of the drive shaft of the first motor 937. The second gear 938 is sleeved on the first screw rod 934 and meshes vertically with the first gear 937, that is, the second gear 938 rotates in a radial direction perpendicular to the axial direction while the first gear 937 rotates, that is, a 90° turn is achieved.

[0140] The first screw rod 934 is vertically arranged, that is, parallel or approximately parallel to the plane where the first mounting plate 936 is located. In this embodiment, it is threadedly connected to the second gear 938, and can make radial rotations in the opposite direction of rotation relative to the second gear 938 under the rotation drive of the second gear 938. Specifically, in this embodiment, the upper and lower ends of the first screw rod 934 are respectively rotatably connected to a second mounting plate 939, and the second mounting plate 939 and the first mounting plate 936 can be integrally formed or separately arranged. During implementation, the rotational connection between the two ends of the first screw rod 934 and the second mounting plate 939 can be achieved through a rotating bearing 940.

[0141] The first slide 935 is slidably connected to the first screw rod 934, and moves up and down with the rotation of the first screw rod 934. Specifically, in this embodiment, the first slide 935 is located between the two second mounting plates 939 and is disposed at the upper end of the first screw rod 934. Preferably, the first slide 935 is also guided to move in the vertical direction up and down through the first slide rail 941. A first slide groove (not shown) matching the first slide rail 941 is disposed on the inner side surface where the first slide 935 abuts against the first slide rail 941. In this embodiment, the first slide rail 941 is vertically disposed on the first mounting plate 936.

[0142] The outer side surface (the side opposite to the first slide groove) of the first slide 935 protrudes outward to form a first fixed boss 942, and the blood suction member 903 vertically passes through the first fixed boss 942 and is fixed in the first fixed boss 942. The first slide 935 drives the blood suction member 903 to extend into or out of the blood sample tube under the drive of the first screw rod 934. In this embodiment, the first slide 935 is connected to a blood suction member 903, and the blood suction member 903 is used to suction blood samples of different blood types.

[0143] The reagent extraction drive mechanism 932 has a similar structure to the blood extraction drive mechanism 931. In the present embodiment, it specifically includes a seventh drive source 943, a second gear assembly, a second screw rod 944 and a second slide 945, wherein the seventh drive source 943 is also fixed on the above-mentioned first mounting plate 936, specifically fixed on the lower end of the first mounting plate 936, and arranged side by side with the sixth drive source 934. During implementation, the seventh drive source 943 may also adopt a motor, and the drive shaft of the motor 943 horizontally passes through the first mounting plate 936.

[0144] The second gear assembly has the same structure as the first gear assembly, and also includes a first gear 937 and a second gear 938, wherein the first gear 937 is fixed to the top end of the drive shaft of the second motor 943 (i.e., the end passing through the first mounting plate 936), and is driven by the drive shaft of the second motor 943 to rotate axially. The second gear 938 is sleeved on the second screw rod 944 and meshes vertically with the first gear 937, that is, the second gear 938 rotates radially perpendicular to the axial direction while the first gear 937 rotates, that is, a 90° turn is achieved. Of course, the present invention is not limited to the gear assembly structure here, and other transmission structures that can realize the transmission between the drive source and the screw rod are applicable to the present invention.

[0145] The second screw rod 944 is vertically arranged, that is, parallel or approximately parallel to the plane where the first mounting plate 936 is located. In this embodiment, it is threadedly connected to the second gear 938, and can make radial rotation in the opposite direction of rotation relative to the second gear 938 under the rotation drive of the second gear 938. Specifically, in this embodiment, the upper and lower ends of the second screw rod 944 are also rotationally connected to the second mounting plate 939. During implementation, the rotational connection between the two ends of the second screw rod 944 and the second mounting plate 939 can also be achieved through the rotating bearing 940.

[0146] The second slide 945 is slidably connected to the second screw rod 944, and moves up and down with the rotation of the second screw rod 944. Specifically, in this embodiment, the second slide 945 is located between the two second mounting plates 939 and is arranged at the upper end of the second screw rod 944. Preferably, the second slide 945 is also guided in the vertical direction by the second slide rail 946, and a second slide groove (not shown) matching with the second slide rail 946 is arranged on the inner side surface where the second slide 945 abuts against the second slide rail 946. In this embodiment, the second slide rail 946 is vertically arranged on the first mounting plate 936.

[0147] The outer side surface (the side opposite to the second slide groove) of the second slide 945 protrudes outward to form a second fixed boss 947, and the reagent suction member 918 vertically passes through the second fixed boss 947 and is fixed in the second fixed boss 947. The second slide 945 drives the reagent suction member 918 to extend into or out of the reagent tube under the drive of the second screw rod 944. In this embodiment, the second slide 945 is connected to a plurality of reagent suction members 918, preferably seven, and each reagent suction member 918 corresponds to sucking a reagent. During implementation, the plurality of reagent suction members 918 can be connected to an integrated rod 920, and a connecting port 921 is set at the position corresponding to each reagent suction member 918 on the integrated rod 920.

[0148] The first motor 937 , the second motor 943 , the first mounting plate 936 and the lower second mounting plate 939 are all integrated and fixed on a base 948 .

[0149] The rotating drive mechanism 933 is connected to the base 948, thereby realizing the connection with the entire blood extraction drive mechanism 931 and the reagent extraction drive mechanism 932, and is used to drive the two mechanisms 931 and 932 to rotate in the horizontal direction, so that the two mechanisms 931 and 932 are moved to the corresponding blood sample tubes and reagent tubes respectively, and cooperate with the two mechanisms 931 and 932 to complete the automated drive of the blood addition and reagent addition processes.

[0150] The rotating drive mechanism 933 specifically includes an eighth driving source 949 and a rotating shaft 950. During implementation, the eighth driving source 949 can use a third motor 951, and the third motor 951 is connected to the rotating shaft 950 to drive the rotating shaft 950 to rotate; the rotating shaft 950 is connected to the above-mentioned base 948, driving the base 948 to rotate in the horizontal direction, and then synchronously driving the blood extraction drive mechanism 931 and the reagent extraction drive mechanism 932 to move in the horizontal direction.

[0151] Preferably, a liquid level sensor 952 for detecting the liquid levels in the blood suction member 903 and the reagent suction member 918 is also provided on the first mounting plate 936, so that the blood suction member 903 and the reagent suction member 918 can respectively extract blood samples and reagents at set liquid levels.

[0152] Based on the above-mentioned fully automatic thrombus elasticity detection device, the present invention discloses a fully automatic thrombus elasticity detection method, including:

[0153] S1, fill the test cup carrier with test cups.

[0154] S2, the cup clamping mechanism of the detection driving device first moves to the detection cup carrying device under the drive of the detection driving mechanism to remove the detection cup, and moves the clamped detection cup to the detection channel to cover it, and then moves the detection cup with the cup cover removed to the reagent storage device and the blood sample carrying device to add reagents and blood samples to the detection cup respectively. After adding, the detection cup is moved and loaded onto the detection channel.

[0155] S3, the detection channel performs blood coagulation data detection.

[0156] S4, after the detection is completed, the detection drive device removes the detection cup from the detection channel.

[0157] S5, after the detection is completed, the cup clamping mechanism is driven by the detection driving mechanism to unload the detection cup onto the waste collection device.

[0158] S6, repeat the above steps S1 to S5.

[0159] The specific implementation process of each step can refer to the description in the above device, which will not be repeated here.

[0160] The technical contents and technical features of the present invention have been disclosed as above. However, those skilled in the art may still make various substitutions and modifications based on the teachings and disclosures of the present invention without departing from the spirit of the present invention. Therefore, the protection scope of the present invention should not be limited to the contents disclosed in the embodiments, but should include various substitutions and modifications that do not depart from the present invention and are covered by the claims of this patent application.

Claims

1. A fully automatic thrombus elasticity detection device, characterized in that: It includes a control device, and a detection cup carrying device connected to the control device, a detection drive device, multiple detection channels, a reagent storage device, a blood sample carrying device and a liquid adding device, wherein: The testing cup carrying device carries a plurality of testing cups required for testing; The detection drive device includes a cup clamping mechanism and a detection drive mechanism connected to the cup clamping mechanism. The cup clamping mechanism is driven by the detection drive mechanism to move to the detection cup carrying device, each detection channel, and the liquid adding device, and at least automatically takes the cup, and cooperates with the process of removing the cup cover, adding reagents and blood samples, and blood testing; The detection channel is used to automatically complete the blood detection process. The detection channel includes a cup-beating device, which is used to unload the cup cover from the detection rod into the detection cup. The cup-beating device includes a driving source, a driving rod and a beating plate. The driving source drives the driving rod to rotate. The beating plate is threadedly connected to the driving rod and can move up and down relative to the screw rod. A through hole is formed on the beating plate for the detection rod to pass through. The reagent storage device carries a plurality of reagent tubes, each of which contains a reagent. The reagent storage device comprises a shell, a conductive base installed in the shell, a conductive drawer for placing reagents, and an interlocking mechanism for pressing and locking the conductive drawer and the conductive base, wherein the conductive drawer is movably installed on the conductive base, the interlocking mechanism comprises a locking assembly installed on the conductive base and a track groove installed on the conductive drawer, the track groove comprises a limiting groove, the locking assembly comprises a rotating member and an elastic member for driving the rotating member to reset, one end of the rotating member is pivotally connected to the conductive base, and the opposite end is provided with a locking pin extending into the track groove, and the elastic member is connected to the rotating member; The blood sample carrying device carries a plurality of blood sample test tubes, each of which contains a type of blood sample; The liquid adding device moves to the reagent storage device and the blood sample carrying device respectively, extracts the reagent and the blood sample respectively, and adds the extracted reagent and the blood sample into the detection cup respectively.

2. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The detection cup carrying device comprises a detection cup tray and a first rotating disk. The detection cup tray is installed on the first rotating disk and carries a plurality of detection cups.

3. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The detection drive mechanism includes a first lifting drive mechanism, a rotation drive mechanism and a horizontal drive mechanism which are all connected to the cup clamping mechanism. The cup clamping mechanism is driven by the first lifting, rotation and horizontal drive mechanisms to move to the detection cup carrying device, each detection channel and the liquid adding device respectively.

4. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The liquid adding device comprises a liquid circuit system and a blood extraction drive mechanism, a reagent extraction drive mechanism and a rotation drive mechanism connected to the liquid circuit system. The blood extraction drive mechanism is connected to the blood suction member to drive the blood suction member to extend into or out of the blood sample test tube; The reagent extraction drive mechanism is connected to the reagent suction piece, driving the reagent suction piece to extend into or out of the reagent tube; the rotation drive mechanism is connected to both the blood extraction drive mechanism and the reagent extraction drive mechanism, and is used to drive both to move to the reagent storage device and the blood sample carrying device respectively.

5. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The blood sample carrying device comprises a second rotating disk and a blood sample tray mounted on the second rotating disk, and the blood sample tray carries a plurality of blood sample tubes.

6. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The thrombus elasticity detection device also includes a waste collection device for collecting the used detection cups transferred by the detection drive device.

7. The fully automatic thrombus elasticity detection device according to claim 6, characterized in that: The control device, the detection cup carrying device, the detection driving device, the multiple detection channels, the reagent storage device, the blood sample carrying device, the liquid adding device and the waste collecting device are all integrated in an outer cover.

8. The fully automatic thrombus elasticity detection device according to claim 1, characterized in that: The detection channel includes a rotating mechanism connected to the detection cup and a second lifting drive mechanism, the rotating mechanism is used to control the detection cup to perform rotational movement during detection, and the second lifting drive mechanism is used to lift the detection cup to a set height.

9. A detection method based on the fully automatic thrombus elasticity detection device according to any one of claims 1 to 8, characterized in that: The method comprises: S1, filling the test cup carrying device with test cups; S2, the cup clamping mechanism of the detection driving device is driven by the detection driving mechanism to first move to the detection cup carrying device to remove the detection cup, and then move the clamped detection cup to the detection channel to cover it, and then move the detection cup without the cup cover to the reagent storage device and the blood sample carrying device to add reagents and blood samples to the detection cup respectively, and after adding, move the detection cup and load it onto the detection channel; S3, the detection channel performs blood coagulation data detection; S4, after the detection is completed, the detection drive device removes the detection cup from the detection channel; S5, after the detection is completed, the cup clamping mechanism is driven by the detection driving mechanism to unload the detection cup onto the waste collection device; S6, repeat the above steps S1 to S5.

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