A foldable medical double chamber bag with sealing attachment

Abstract

The present invention relates to a foldable medical double-chamber bag with a sealing attachment, comprising an infusion bag and a sealing assembly, wherein the sealing assembly comprises a sealing outer member and a sealing inner member installed in cooperation with the sealing outer member, wherein a portion of the infusion bag is folded and pressed between the sealing outer member and the sealing inner member, wherein the sealing assembly divides the infusion bag into chamber A and chamber B, wherein an infusion port is provided at one end of the infusion bag, wherein the infusion port is connected to chamber B, wherein a pull ring cover for a puncture device to establish an infusion channel is installed at the infusion port, and a hook is provided at one end of the infusion bag away from the infusion port. The sealing assembly cooperates with a folding and pressing process to realize an isolation layout between chamber A and chamber B; the sealing assembly in the form of an external attachment enables the chamber opening operation to be realized by only removing the sealing outer member, and there is no destructive operation inside the infusion bag, which, on the one hand, does not generate particles, and on the other hand, reduces the difficulty of the opening operation between the two chambers.

Description

Technical Field

[0001] The invention relates to the technical field of medical multi-chamber infusion bags, in particular to a foldable medical double-chamber bag with sealing accessories. Background Art

[0002] Liquid preparations refer to liquid dispersion systems for oral or external use in which drugs are dispersed in a certain form in a liquid medium. They have the advantages of large dispersion, fast absorption, multiple routes of administration, oral and external use, easy division of doses, convenient administration, and reduced irritation of certain drugs. However, there is a common problem of poor chemical stability, so liquid preparations are generally required to have higher physical, chemical and biological stability during the production process to ensure the safety and effectiveness of the product during the storage period. For some drugs that are unstable in solution, such as penicillin, cephalosporins, and some medical enzyme preparations or biological preparations, they generally need to be made into sterile powder for injection and prepared on site before use.

[0003] Medical multi-chamber infusion bags are a type of ready-to-mix infusion product, including bags for isolating drug liquid from drug powder and bags for isolating drug liquid from drug liquid. Before use, the chambers of the infusion bag are different from each other. When in use, medical staff open the isolation between the chambers to fully mix the drug components in the chambers for clinical use.

[0004] A new type of multi-chamber infusion bag with a weak welding isolation strip structure is disclosed in the Chinese invention patent application document with application number CN107374962A, which includes a plurality of chambers isolated from each other, and each chamber is isolated by a weak welding rod; it is characterized in that two weak welding rods are arranged between the chambers, an isolation buffer cavity is arranged between the two weak welding rods, and the weak welding rod is wavy.

[0005] The above application documents propose the use of a double-layer wavy weak-weld isolation bag to adjust the stress distribution of the weak-weld part and improve the opening efficiency, and the use of a double-layer weak-weld belt improves the ability to prevent accidental opening; however, the weak-weld process constitutes an isolation belt, and the tearing operation during use may produce particles, and the number and size of the particles produced are not only related to the product design process but also to the user's operation, so there is a large uncertainty; at the same time, there is still a weak-weld opening operation, and because the number of weak-weld layers is increased, the risk of particles generated during opening is increased. Moreover, in recent years, it has been found in the process of using infusion bags with isolation that medical staff often forget to open the isolation during use, and only provide patients with a chamber solution. Summary of the invention

[0006] In view of the shortcomings of the prior art, the object of the present invention is to provide a foldable medical double-chamber bag with a sealing attachment.

[0007] The above-mentioned object of the present invention is achieved through the following technical solutions:

[0008] A foldable medical double-chamber bag with a sealing attachment comprises an infusion bag and a sealing assembly, wherein the sealing assembly comprises a sealing outer component and a sealing inner component installed in cooperation with the sealing outer component, wherein a portion of the infusion bag is folded and pressed between the sealing outer component and the sealing inner component, wherein the sealing assembly divides the infusion bag into chamber A and chamber B, wherein an infusion port is provided at one end of the infusion bag, wherein the infusion port is connected to chamber B, wherein a pull ring cover for a puncture device to establish an infusion channel is installed at the infusion port, and a hook is provided at the end of the infusion bag away from the infusion port.

[0009] By adopting the above technical solution, before using the medical double-chamber bag, different liquid medicines can be placed in chamber A and chamber B respectively, or liquid medicine can be placed in one chamber and powder medicine can be placed in the other chamber. When both chamber A and chamber B contain liquid medicine, there is no special requirement for the placement position; when powder medicine needs to be placed in the infusion bag, the powder medicine needs to be placed in chamber B. When in use, firstly, the sealing inner member is pulled out to release the pressure of the folded part of the infusion bag, and then the sealing outer member is removed, and the folded infusion bag is opened to connect chamber A and chamber B, so as to achieve mixing between the objects placed in chamber A and chamber B. The sealing component cooperates with the folding and pressing process to realize the isolation layout between chamber A and chamber B; the sealing component in the form of an external accessory makes it possible to realize the chamber opening operation by only removing the sealing outer member, and there is no destructive operation inside the infusion bag. On the one hand, no particles will be generated, and on the other hand, the difficulty of opening the two chambers is reduced, which can significantly improve the safety, stability and practicality of the product and ensure the mixing efficiency of the objects placed in the infusion bag. The sealing component combined with the folding and pressing technology can better cope with unexpectedly increased chamber pressure, thus improving the safety and reliability of the infusion bag during transportation and storage. At the same time, it can prevent operators from mistakenly infusing only one type of liquid medicine into the patient without mixing the medicine, significantly improving the reliability of the product during use.

[0010] In a preferred example, the present invention can be further configured as follows: the inner sealing component is a triangular rod, the outer sealing component is a U-shaped rod, the inner sealing component includes a bottom edge and two equal side edges, and arc-shaped top edges are arranged at both ends of the opening of the outer sealing component, and the arc-shaped top edges are arranged toward the two side edges of the inner sealing component.

[0011] By adopting the above technical solution, the medical double-chamber bag will inevitably encounter extrusion during transportation or storage. When the infusion bag is squeezed, the pressure at both ends of chamber A and chamber B increases, thereby increasing the tension between the sealing inner component and the sealing outer component. An arc-shaped top edge is set at both ends of the opening of the sealing outer component, and the sealing inner component is set as a triangular rod with equal sides. During the extrusion process, as the pressure in the chamber increases, part of the pressure acts on the two sides of the sealing inner component. The increase in pressure on the two sides eventually increases the extrusion force between the bottom edge of the sealing inner component and the inner wall of the sealing outer component, thereby improving the sealing effect of the sealing component on the infusion bag, and ensuring the safety and reliability of the infusion bag during transportation and storage.

[0012] In a preferred example, the present invention can be further configured as follows: the two corners of the sealing inner component away from the arc-shaped top edge are set as arc-shaped top angles, and two beveled edges are extended on the inner side of the sealing outer component, and the beveled edges are located on the side of the sealing outer component away from its opening and are arranged opposite to the arc-shaped top angle.

[0013] By adopting the above technical solution, in the initial state after folding and pressing, the arc top edge and the side wall of the sealing inner member mainly provide sealing effect to chamber A and chamber B. When the pressure rises to a level exceeding the sealing strength of the above matching state during transportation or storage, the arc top edge and the side wall of the sealing inner member are slightly opened under the action of pressure, and the liquid invades between the arc top angle and the beveled edge set on the inner side of the sealing outer member. At this time, in addition to the pressing and sealing effect between the arc top angle and the beveled edge on the infusion bag, the arc top edge and the side edge, as well as the arc top angle and the beveled edge, use the lever principle to improve the sealing effect between the arc top edge and the beveled edge by using the additional pressure brought by the expansion between the arc top edge and the side edge; at the same time, the pressure relief effect of the small gap between the arc top edge and the side edge and the arc top angle and the beveled edge also improves the sealing effect of the infusion bag to a certain extent. The additional sealing effect brought about by the additional pressure expanding outward between the arc-shaped top edge and the side edges increases as the pressure in the chamber increases, and when the pressure in the chamber decreases, the arc-shaped top edge and the bevel edge can rebound to the initial state and restore the sealing ability.

[0014] In a preferred example, the present invention can be further configured as follows: the installation distances between the arc-shaped top edge and the side edge and between the arc-shaped top angle and the hypotenuse are all smaller than the thickness of the infusion bag.

[0015] By adopting the above technical solution, the installation distance between the arc top edge and the side edge and between the arc top corner and the hypotenuse is set to be smaller than the thickness of the infusion bag, thereby obtaining a partial fitting pressure between the sealing outer component and the sealing inner component, thereby constituting the initial sealing strength of the sealing assembly.

[0016] In a preferred example, the present invention can be further configured as follows: an aluminum foil layer is compounded on the outer wall of the infusion bag to improve its light-shielding ability.

[0017] By adopting the above technical solution, when the infusion bag contains medicine powder that needs to be kept away from light, an aluminum foil layer can be provided on the outer wall of the infusion bag, thereby increasing the application range of the medical double-chamber bag and improving the practicality of the medical double-chamber bag.

[0018] In a preferred example, the present invention can be further configured as follows: the pull-ring cover adopts a pull-ring type polypropylene combined cover.

[0019] By adopting the above technical solution, the pull ring cover adopts a pull ring type polypropylene combined cover, which has universal applicability.

[0020] In a preferred example, the present invention can be further configured as follows: the infusion bag body is one or more of a polyethylene bag body, a polypropylene bag body, a polybutylene bag body, a SEBS bag body, a PVC bag body or a non-PVC co-extruded infusion film hot-pressed bag body.

[0021] By adopting the above technical solution, infusion bag bodies made of different materials can be used to contain the liquid or medicine powder placed in the infusion bag according to the different chemical and physical properties of the liquid or medicine powder placed in the infusion bag.

[0022] In summary, the present invention includes at least one of the following beneficial technical effects:

[0023] 1. By setting up a sealing component, the sealing component cooperates with the folding and pressing process to realize the isolation layout between chamber A and chamber B; the sealing component in the form of an external accessory makes it possible to open the chambers only by removing the sealing external component, and there is no destructive operation inside the infusion bag. On the one hand, no particles will be generated, and on the other hand, the difficulty of opening the two chambers is reduced, which can significantly improve the safety, stability and practicality of the product and ensure the mixing efficiency of the objects placed in the infusion bag. The sealing component combined with the folding and pressing technology can better cope with unexpected increases in chamber pressure, thereby improving the safety and reliability of the infusion bag during transportation and storage. At the same time, it can avoid the situation where the operator fails to mix the drugs due to mistakes and only injects one kind of liquid medicine into the patient, which significantly improves the reliability of the product during use;

[0024] 2. By setting arc-shaped top edges at both ends of the opening of the sealing outer member, and setting the sealing inner member as a triangular rod with equal sides, during the extrusion process, as the pressure in the chamber rises, part of the pressure acts on the two sides of the sealing inner member. The increase in the pressure on the two sides eventually increases the extrusion force between the bottom edge of the sealing inner member and the inner wall of the sealing outer member, thereby improving the sealing effect of the sealing assembly on the infusion bag;

[0025] 3. By setting the two corners of the sealing inner member away from the arc top edge as arc top angles, and extending two beveled edges on the inner side of the sealing outer member, when the pressure rises to a level exceeding the above-mentioned sealing state during transportation or storage, in addition to the compression sealing effect on the infusion bag between the arc top angle and the beveled edges, the arc top edge and the side edges, as well as between the arc top angle and the beveled edges, use the lever principle to enhance the sealing effect between the arc top angle and the beveled edges by utilizing the extra pressure brought about by the outward expansion between the arc top edge and the side edges; at the same time, the pressure relief effect of the tiny gap passage between the arc top edge and the side edges and between the arc top angle and the beveled edges also improves the sealing effect of the infusion bag to a certain extent. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is an overall schematic diagram of Example 1;

[0027] Figure 2 is a cross-sectional schematic diagram of the infusion bag in Example 1 when it is unfolded;

[0028] Figure 3 is a schematic structural diagram of the cooperation between the sealing inner component and the sealing outer component in Example 1;

[0029] Figure 4 It is an overall schematic diagram of Example 2.

[0030] Figure numerals: 1. infusion bag; 11. chamber A; 12. chamber B; 2. sealing assembly; 21. sealing inner member; 211. side; 212. bottom; 22. sealing outer member; 3. infusion port; 4. pull ring cover; 5. hook; 6. aluminum foil layer; 7. arc-shaped top edge; 8. arc-shaped top corner; 9. bevel; 10. dosing tube. DETAILED DESCRIPTION

[0031] The present invention is further described in detail below in conjunction with the accompanying drawings.

[0032] Embodiment 1:

[0033] Reference Figure 1 and Figure 2 , is a foldable medical double-chamber bag with sealing accessories disclosed in the present invention, comprising an infusion bag 1 and a sealing assembly 2. The bag body of the infusion bag 1 can be one or more of a polyethylene bag body, a polypropylene bag body, a polybutylene bag body, a SEBS bag body, a PVC bag body or a non-PVC co-extruded infusion film hot-pressed bag body. Preferably, the material of the infusion bag 1 is a conventional bag body made of PVC material. The capacity of the infusion bag 1 can be 50ml-5000ml, preferably 100ml-1500ml; the wall thickness of the infusion bag 1 ranges from 0.2mm-1.0mm, preferably 0.2mm-0.5mm.

[0034] The sealing assembly 2 includes a sealing outer member 22 and a sealing inner member 21 installed in cooperation with the sealing outer member 22. The sealing inner member can be made of glass, polymer or metal materials. When a polymer material is selected, it can be PE, PTFE, PP, etc., among which HDPE and PTFE are preferred. When a metal material is selected, it can be 304, 316, 316L, nickel-titanium alloy, aluminum alloy, etc., among which 304 and 316 are preferred. The sealing outer member can be made of polymer or metal materials. When a polymer material is selected, it can be PE, PTFE, PP, etc., among which HDPE and PTFE are preferred. When a metal material is selected, it can be 304, 316, 316L, nickel-titanium alloy, aluminum alloy, etc., among which 304 and 316 are preferred.

[0035] Part of the infusion bag 1 can be folded and installed between the sealing inner member 21 and the sealing outer member 22 by low-temperature pressing and folding technology. Among them, in the low-temperature pressing and folding technology, low temperature refers to the temperature range in which the material of the infusion bag 1 used can be softened and deformed but not melted, and then heated and stabilized under pressure to make the infusion bag 1 material and the shape of the sealing inner member fit evenly, and remove the air contained in the folding interval of the sealing bag. After low-temperature pressing, when there is no external force, the infusion bag 1 should maintain the same shape as the sealing inner member for a short time without falling apart.

[0036] The interior of the infusion bag 1 is separated into chamber A11 and chamber B12 by a sealing component 2. A circular infusion port 3 is provided at one end of the infusion bag 1. The infusion port 3 is connected to the chamber B12. A pull ring cover 4 is installed at the infusion port 3 for the puncture device to establish an infusion channel. The pull ring cover 4 adopts a pull ring type polypropylene composite cover. A hook 5 for hanging the infusion bag 1 is provided at one end of the infusion bag 1 away from the pull ring cover 4.

[0037] Reference Figure 1 and Figure 3 , the infusion bag 1 is in a folded state before use. At this time, different liquid medicines can be placed in chamber A11 and chamber B12 respectively, or liquid medicine can be placed in one chamber and powder medicine can be placed in the other chamber. When liquid medicine is placed in both chamber A11 and chamber B12, there is no special requirement for the placement position; when powder medicine needs to be placed in the infusion bag 1, the powder medicine needs to be placed in chamber B12. And when the infusion bag 1 is folded, the hook 5 and the infusion port 3 face the same direction. An aluminum foil layer 6 is compounded on the outer wall of the infusion bag 1. When chamber B is filled with liquid medicine or powder medicine that needs to be kept away from light, the aluminum foil layer 6 can have a certain light-shielding effect on it.

[0038] When the infusion bag 1 is in use, the sealing inner component 21 is firstly pulled out to release the pressure of the folded part of the infusion bag 1, and then the sealing outer component 22 is removed, and the folded infusion bag 1 is opened to connect the chamber A11 and the chamber B12, so as to achieve mixing between the objects placed in the chamber A11 and the chamber B12. When removing the sealing component 2, there is no destructive operation inside the infusion bag 1, and no particles are generated, which can avoid the risk of generating particles when the weak welding isolation is torn, and reduce the difficulty of the operation of opening the two chambers, which can significantly improve the safety, stability and practicality of the product, and also ensure the mixing efficiency of the objects placed in the infusion bag 1.

[0039] The sealing inner component 21 is a triangular rod, and the sealing outer component 22 is a U-shaped rod. The sealing inner component 21 includes a bottom edge 212 and two equal side edges 211. The two ends of the opening of the sealing outer component 22 are integrally formed with an arc-shaped top edge 7 with a semicircular cross-section, and the arc-shaped top edges 7 are both arranged toward the two side edges 211 of the sealing inner component 21.

[0040] When the infusion bag 1 is squeezed, the pressure in the chamber A11 and the chamber B12 increases, thereby increasing the tension between the sealing inner member 21 and the sealing outer member 22. During the squeezing process, as the pressure in the chamber increases, part of the pressure acts on the two side edges 211 of the sealing inner member 21. The increase in the pressure on the two side edges 211 eventually increases the squeezing force between the bottom edge 212 of the sealing inner member 21 and the inner wall of the sealing outer member 22, thereby improving the sealing effect of the sealing assembly 2 on the infusion bag 1.

[0041] The two corners of the sealing inner component 21 away from the arc-shaped top edge 7 are set as arc-shaped top corners 8. The inner side of the sealing outer component 22 is extended with two beveled edges 9. The beveled edges 9 are located on the side of the sealing outer component 22 away from its opening and are arranged opposite to the arc-shaped top corners 8.

[0042] In the initial state after folding and pressing, the arc top edge 7 and the side wall of the sealing inner member 21 mainly provide sealing effect to the chamber A11 and the chamber B12. When the pressure rises to exceed the above sealing state during transportation or storage, the arc top edge 7 and the side wall of the sealing inner member 21 are slightly opened under the action of pressure, and the liquid invades between the arc top corner 8 and the bevel 9 set on the inner side of the sealing outer member 22. At this time, in addition to the compression sealing effect between the arc top corner 8 and the bevel 9 on the infusion bag 1, the arc top edge 7 and the side edge 211 and the arc top angle 8 and the bevel 9 are sealed by the lever principle, and the additional pressure brought by the expansion between the arc top edge 7 and the side edge 211 is used to enhance the sealing effect between the arc top edge 8 and the bevel 9; at the same time, the pressure relief effect of the small gap between the arc top edge 7 and the side edge 211 and the arc top angle 8 and the bevel 9 also improves the sealing effect of the infusion bag 1 to a certain extent. The additional sealing effect brought about by the additional pressure expanding outward between the arc-shaped top edge 7 and the side edge 211 increases as the pressure in the chamber increases. When the pressure in the chamber decreases, the arc-shaped top edge 7 and the oblique edge 9 can rebound to the initial state and restore the sealing ability.

[0043] When the sealing outer member 22 and the sealing inner member 21 are in a matched installation state, the installation distance between the arc top edge 7 and the side edge 211 and the arc top angle 8 and the oblique edge 9 is less than the thickness of the infusion bag 1. When the sealing inner member 21 and the sealing outer member 22 are matched and installed, the space for placing the infusion bag 1 is 70%-90% of the wall thickness of the infusion bag 1, and the preferred range is 75%-85%. At least a squeezing space of 0.1 mm or more of the thickness of the infusion bag 1 used needs to be provided.

[0044] The implementation principle of this embodiment is: before using the medical double-chamber bag, different liquid medicines can be placed in chamber A11 and chamber B12 respectively, or liquid medicine can be placed in one chamber and powder medicine can be placed in the other chamber. When both chamber A11 and chamber B12 contain liquid medicine, there is no special requirement for the placement position; when powder medicine needs to be placed in the infusion bag 1, the powder medicine needs to be placed in chamber B12. When in use, first pull out the sealing inner component 21 to release the pressure of the folded part of the infusion bag 1, then remove the sealing outer component 22, open the folded infusion bag 1 to connect chamber A11 and chamber B12, and achieve mixing between the objects placed in chamber A11 and chamber B12.

[0045] The sealing component cooperates with the folding and pressing process to realize the isolation layout between chamber A and chamber B; the sealing component in the form of an external accessory makes it possible to open the chambers by simply removing the sealing outer component, and there is no destructive operation inside the infusion bag. On the one hand, it will not produce particles, and on the other hand, it reduces the difficulty of opening the two chambers, which can significantly improve the safety, stability and practicality of the product and ensure the mixing efficiency of the objects placed in the infusion bag. The sealing component combined with the folding and pressing technology can better cope with unexpectedly increased chamber pressure, thereby improving the safety and reliability of the infusion bag during transportation and storage. At the same time, it can avoid the situation where the operator fails to mix the drugs due to mistakes and only injects one kind of liquid into the patient, significantly improving the reliability of the product during use.

[0046] Embodiment 2:

[0047] The difference between this embodiment and the first embodiment is: Figure 4 Both ends of the infusion bag 1 are provided with drug adding tubes 10, and the drug adding tubes 10 are respectively connected with the chamber A and the chamber B.

[0048] Beneficial effects of this embodiment: By providing the drug adding tube 10 , when the medical double-chamber bag is used, other drug liquids or drug powders can be added into chamber A or chamber B through the drug adding tube 10 .

[0049] The embodiments of this specific implementation method are all preferred embodiments of the present invention, and are not intended to limit the protection scope of the present invention. Therefore, any equivalent changes made based on the structure, shape, and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A foldable medical double chamber bag with sealing attachment, characterized in that: The invention comprises an infusion bag (1) and a sealing assembly (2), wherein the sealing assembly (2) comprises a sealing outer component (22) and a sealing inner component (21) mounted in cooperation with the sealing outer component (22), wherein a portion of the infusion bag (1) is folded between the sealing outer component (22) and the sealing inner component (21), and the sealing assembly (2) divides the infusion bag (1) into a chamber A (11) and a chamber B (12). An infusion port (3) is provided at one end of the infusion bag (1), wherein the infusion port (3) is connected to the chamber B (12), and a pull ring cover (4) is installed at the infusion port (3) for a puncture device to establish an infusion channel. A hook (5) is provided at one end of the infusion bag (1) away from the infusion port (3); the sealed inner component (21) is a triangular rod, the sealed outer component (22) is a U-shaped rod, the sealed inner component (21) comprises a bottom edge (212) and two equal side edges (211), arc-shaped top edges (7) are provided at both ends of the opening of the sealed outer component (22), and the arc-shaped top edges (7) are both arranged towards the two side edges (211) of the sealed inner component (21); two corners of the sealed inner component (21) away from the arc-shaped top edge (7) are arranged as arc-shaped top angles (8), and two oblique edges (9) are extended from the inner side of the sealed outer component (22), and the oblique edges (9) are located on the side of the sealed outer component (22) away from the opening thereof and are arranged opposite to the arc-shaped top angle (8); an aluminum foil layer (6) for improving its light-shielding ability is compounded on the outer wall of the infusion bag.

2. A foldable medical double chamber bag with sealing attachment according to claim 1, characterized in that: The installation distances between the arc-shaped top edge and the side edge, and between the arc-shaped top angle and the oblique edge are all smaller than the thickness of the infusion bag (1).

3. A foldable medical double chamber bag with sealing attachment according to claim 1, characterized in that: The pull ring cover (4) is a pull ring type polypropylene combined cover.

4. A foldable medical double chamber bag with sealing attachment according to claim 1, characterized in that: The bag body of the infusion bag (1) is one or more of a polyethylene bag body, a polypropylene bag body, a polybutylene bag body, a SEBS bag body, a PVC bag body or a non-PVC co-extruded infusion film hot-pressed bag body.

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