Intracavity blocking device, sleeve-type intracavity blocking device and lotus-type intracavity blocking device

Abstract

The present invention provides an intracavitary occlusion device, comprising a skeleton and a flow-blocking membrane covering the skeleton, wherein the skeleton comprises a plurality of first segments and second segments arranged alternately at intervals, the flow-blocking membrane comprises a plurality of first regions corresponding to each first segment and a second region corresponding to each second segment, at least one first segment being fixedly connected to a corresponding first region, and / or at least one second segment being fixedly connected to a corresponding second region, the skeleton being foldable and retractable to form a protrusion at the position of the first segment and a recess at the position of the second segment, the protrusions and recesses being arranged alternately at intervals in sequence. The present invention solves the technical problem that existing occlusion devices cannot adapt to the uneven shape of the cavity inner wall, resulting in poor occlusion effect of the occlusion devices.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, and in particular to an intracavity blocking device, a sleeve-type intracavity blocking device, and a coupler-type intracavity blocking device. Background Art

[0002] Interventional therapy is an emerging treatment approach between surgical and medical treatments, encompassing both intravascular and non-vascular interventional therapies. Simply put, interventional therapy involves creating a tiny channel, a few millimeters in diameter, through blood vessels or skin, or through existing body channels, without surgically exposing the lesion. This minimally invasive treatment approach involves treating the lesion locally under the guidance of imaging equipment (angiography, fluoroscopy, etc.). Interventional therapy offers advantages such as minimal trauma, simplicity, safety, effectiveness, minimal complications, and significantly shortened hospital stays.

[0003] As implants for interventional therapy, occlusion devices can be used to block defects, tissue ruptures, lumens, and organ passages in the human and / or animal body. For example, these devices are widely used in clinical practice to treat congenital heart disease, including atrial septal defects, ventricular septal defects, and patent arterial sheaths. The principle behind these occlusion devices is to block the "holes" between the left and right atria, the "holes" between the left and right ventricles, and the passages between the aorta and pulmonary artery.

[0004] Aortic dissection, on the other hand, is caused by a tear in the aortic intima and media, resulting in separation of the intima from the media, allowing blood to flow in and dividing the aortic lumen into a true and false lumen. Typical aortic dissections demonstrate a septum or intimal flap between the true and false lumens, which may or may not communicate. Conventional endovascular aortic repair for aortic dissection generally aims to seal the primary rupture and reduce pressure in the false lumen to achieve aortic remodeling. However, data indicate that this objective is not achieved in 7% to 20% of cases due to incomplete thrombosis of the false lumen. The presence of a distal rupture and continued perfusion (unthrombotic false lumen) increases the risk of continued false lumen enlargement, which in turn increases the risk of further dissection tears and aneurysm rupture, and also increases the incidence of surgical reintervention after endovascular repair. Currently, adjunctive techniques are used after standard endovascular aortic repair to promote thrombosis of the false lumen. For example, embolization can be used to promote thrombosis of the false lumen. Following standard endovascular repair, a distal bare stent and a false lumen embolic device are simultaneously implanted. The visceral artery supplying the false lumen is also stented. Embolic devices typically include steel coils and embolic adhesives, which have achieved some clinical success. However, these embolic devices are not specifically targeted for dissecting false lumens and are purely empirical, making them difficult to generalize. Alternatively, some surgeons may choose to implant a vascular occlusion device into the false lumen to reduce distal reflux and promote thrombosis. Similarly, this technique is limited by the nonspecific nature of vascular occlusion devices, making it difficult to determine the morphology and location of the false lumen during operation. Whether this technique increases the risk of false lumen rupture during the procedure remains to be verified.

[0005] The above-mentioned interventional treatment method is to block the inner cavity (defect opening, tissue rupture, inner cavity, organ channel) of the human and / or animal body by using a blocking device, but the existing blocking device cannot adapt to the uneven shape of the cavity wall, and the blocking effect of the blocking device is poor. Summary of the Invention

[0006] The present invention provides an intracavity blocking device, a sleeve-type intracavity blocking device and a lotus-type intracavity blocking device to solve the technical problem that the existing blocking devices cannot adapt to the uneven shape of the cavity inner wall and the blocking effect of the blocking devices is poor.

[0007] The present invention provides an intracavitary occlusion device, comprising a skeleton and a flow-blocking membrane covering the skeleton, wherein the skeleton comprises a plurality of first segments and second segments alternately arranged at intervals, and the flow-blocking membrane comprises a plurality of first areas corresponding to each first segment and a second area corresponding to each second segment, at least one first segment is fixedly connected to the corresponding first area, and / or at least one second segment is fixedly connected to the corresponding second area, and the skeleton is foldable and retractable to form a protrusion at the position of the first segment and a recess at the position of the second segment, and the protrusion and the recess are alternately arranged at intervals in sequence.

[0008] Each of the protrusions is fixedly connected to the corresponding first area, and a first pleated structure is formed between adjacent first areas, so that the axial stretchable length of the flow-blocking membrane is greater than or equal to the axial stretching length of the skeleton.

[0009] Each of the recesses is fixedly connected to the corresponding second area, and a second pleated structure is formed between adjacent second areas, so that the axial stretchable length of the flow-blocking membrane is greater than or equal to the axial stretching length of the skeleton.

[0010] The concave portion includes a concave bottom, the second area includes a second connecting position corresponding to the concave bottom, and the concave bottom is fixedly connected to the second connecting position.

[0011] Wherein, the flow-blocking membrane is an elastic membrane.

[0012] Wherein, when the skeleton is folded and compressed, the central axes of the protruding parts are arranged at equal distances, and the central axes of the concave parts are arranged at equal distances.

[0013] In which, a plurality of first alignment marks are provided on the baffle film, and the plurality of first alignment marks are provided on the first area, and the first alignment marks are used to align the first area with the first segment; and / or a plurality of second alignment marks are provided on the baffle film, and the plurality of second alignment marks are provided on the second area, and the second alignment marks are used to align the second area with the second segment.

[0014] Wherein, at least one of the first alignment marks is fixedly connected to the corresponding first segment, and / or at least one of the second alignment marks is fixedly connected to the corresponding second segment.

[0015] The second alignment mark is provided on the second connection position, and the second alignment mark is used to align the second connection position with the concave bottom.

[0016] Wherein, the second alignment mark is fixedly connected to the concave bottom.

[0017] The first section is fixedly connected to the first area via a suture, and the second section is fixedly connected to the second area via a suture.

[0018] Wherein, the material of the suture thread is polytetrafluoroethylene.

[0019] The curvature of the top of the protrusion located at the two axial ends of the skeleton is smaller than the curvature of the top of the protrusion located between the two axial ends of the skeleton.

[0020] Wherein, the cross section of the skeleton is in the shape of a full moon, a crescent moon, a waxing crescent moon or a waning moon.

[0021] Wherein, the shapes of the protrusion and the recess are semicircular, square or triangular.

[0022] The frame includes two oppositely arranged first and second bottom walls, the first sections and the second sections alternately form a peripheral wall, and the first bottom wall and the second bottom wall are arranged at opposite ends of the peripheral wall.

[0023] Wherein, the frame includes a sleeve and a bolt head, the sleeve is arranged on the first bottom wall, and the bolt head is arranged on the second bottom wall.

[0024] The skeleton is a mesh structure woven of metal wires, wherein the ends of the metal wires at one end are gathered together and fixed in the sleeve, and the ends of the metal wires at the other end are gathered together and fixed in the bolt head.

[0025] The present invention provides a lotus-type intracavity blocking device, comprising at least one of the above-mentioned intracavity blocking devices.

[0026] There are at least two intracavitary blocking devices, and the proximal end of one intracavitary blocking device is connected to the distal end of another intracavitary blocking device via a collar.

[0027] The present invention provides a sleeve-type intracavity blocking device, characterized in that it comprises at least one of the above-mentioned intracavity blocking devices.

[0028] Among them, there are at least two intracavity blocking devices, and the two intracavity blocking devices are respectively a first intracavity blocking device and a second intracavity blocking device. The axial length of the first intracavity blocking device is smaller than the axial length of the second intracavity blocking device. The first intracavity blocking device is sleeved in the second intracavity blocking device. The first intracavity blocking device is connected to the proximal end of the second intracavity blocking device, and the distal end of the first intracavity blocking device is connected to the distal end of the second intracavity blocking device through an elastic member.

[0029] To sum up, the skeleton of the present invention is foldable and retractable, so that the protrusions and the recesses can form a concave-convex structure of the skeleton, and the flow-blocking membrane covering the skeleton can also form a concave-convex structure following the protrusions and the recesses, so that the flow-blocking membrane can adapt to the uneven shape of the cavity inner wall, so that the flow-blocking membrane and the cavity inner wall fit better, thereby enhancing the force between the sealing device and the cavity inner wall, improving the stability of the sealing device and the cavity inner wall, and thereby improving the sealing effect of the flow-blocking membrane of the cavity sealing device covered on the skeleton. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the technical solution of the present invention, the following is a brief introduction to the drawings required for use in the implementation. Obviously, the drawings described below are only some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained like these drawings without paying any creative work.

[0031] Figure 1 It is a schematic structural diagram of the intracavitary occlusion device provided by the present invention;

[0032] Figure 2 Schematic diagram of the cross-sectional structure of the intracavitary occlusion device provided by the present invention;

[0033] Figure 3 This is a front view structural diagram of the intracavitary occlusion device provided by the present invention;

[0034] Figure 4 yes Figure 3 The schematic cross-sectional structure diagram of the first state of the skeleton in the AA direction is shown;

[0035] Figure 5 yes Figure 3 The schematic cross-sectional structure diagram of the second state of the skeleton in the AA direction is shown;

[0036] Figure 6 It is a structural schematic diagram of the lotus-type intracavitary blocking device provided by the present invention;

[0037] Figure 7 It is a structural schematic diagram of the sleeve-type intracavitary blocking device provided by the present invention. DETAILED DESCRIPTION

[0038] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0039] In the field of minimally invasive intervention, the end relatively far from the operator is usually defined as the distal end, and the end relatively close to the operator is defined as the proximal end.

[0040] See also Figure 1-Figure 5 The present invention provides an intraluminal occlusion device 100, comprising a skeleton 10 and a flow-blocking membrane 20 covering the skeleton 10. The skeleton 10 includes a plurality of alternating first segments 301 and second segments 401. The flow-blocking membrane 20 includes a plurality of first regions 201 corresponding to each first segment 301 and a second region 202 corresponding to each second segment 401. At least one first segment 301 is fixedly connected to a corresponding first region 201, and / or at least one second segment 401 is fixedly connected to a corresponding second region 202. The skeleton 10 is foldable and retractable to form a protrusion 30 at the location of the first segment 301 and a recess 40 at the location of the second segment 401. The protrusions 30 and recesses 40 are arranged in an alternating pattern. In this application, the protrusions 30 and recesses 40 are distinguished by a reference line A. The protrusions 30 are located outward from the reference line A, and the recesses 40 are located inward from the reference line A. When the frame 10 is axially stretched, the height of the protrusion 30 decreases and the depth of the recess 40 decreases. When the frame 10 is axially compressed, the height of the protrusion 30 increases and the depth of the recess 40 increases. When the frame 10 is flattened, both the recess 40 and the protrusion 30 disappear.

[0041] In the present application, the cross-section of the skeleton 10 is in the shape of a full moon, a crescent, a crescent, or a waning moon. The skeleton 10 can also be a conical structure, and the inner diameter of the skeleton 10 decreases or increases from the distal end to the proximal end. The shape of the skeleton 10 can be changed according to the shape of the inner cavity. The shape of the protrusion 30 and the recess 40 is semicircular, square, or triangular. In other embodiments, the shape of the cross-section of the skeleton 10, the shape of the protrusion 30, and the shape of the recess 40 can also be other shapes, which are not limited here.

[0042] The first section 301 is fixedly connected to the first area 201 by a suture 120, and the second section 401 is fixedly connected to the second area 202 by a suture 120. The material of the suture 120 is polytetraethylene fluoride (PTFE). The material of the suture 120 can also be other materials, which are not limited in this application.

[0043] The frame 10 includes two oppositely disposed first and second bottom walls 106 and 107 . The first sections 301 and the second sections 401 alternately form a peripheral wall 180 . The first and second bottom walls 106 and 107 are disposed at opposite ends of the peripheral wall 180 .

[0044] The skeleton 10 includes a sleeve 80 and a bolt 90. The sleeve 80 is arranged on the first bottom wall 106, and the bolt 90 is arranged on the second bottom wall 107. The skeleton 10 is a mesh structure woven with metal wires. The metal wires are cross-woven into a "well"-shaped mesh structure. The metal wires in the mesh structure are oriented obliquely. The ends of the metal wires at one end are gathered and fixed in the sleeve 80, and the ends of the metal wires at the other end are gathered and fixed in the bolt 90. The bolt 90 is connected to the conveyor, generally in the form of a detachable threaded connection or a snap connection; the sleeve 80 is used to gather the braided wires at the end of the braided skeleton, and a steel sleeve can be used. The material of the sleeve 80 and the bolt 90 can be 316L stainless steel. In the present application, a circle of PTFE thread is sewn at the connection between the proximal bolt head 90 and the skeleton mesh, and a circle of PTFE thread is sewn at the connection between the distal sleeve head 80 and the skeleton mesh, which can ensure that the flow-blocking membrane 20 of the intracavitary occlusion device 100 does not separate from the skeleton 10 during the sheathing process, and also has a good flow-blocking effect in the axial direction.

[0045] In the present invention, the skeleton 10 can be folded and stretched, so that the protrusions 30 and the recesses 40 can form a concave-convex structure of the skeleton 10, and the flow-blocking membrane 20 covering the skeleton 10 can also form a concave-convex structure following the protrusions 30 and the recesses 40, so that the flow-blocking membrane 20 can adapt to the uneven shape of the cavity inner wall, so that the flow-blocking membrane 20 and the cavity inner wall fit better, thereby enhancing the force between the sealing device and the cavity inner wall, improving the stability of the sealing device and the cavity inner wall, and thereby improving the sealing effect of the flow-blocking membrane 20 of the cavity sealing device 100 covered on the skeleton.

[0046] Moreover, since the arteries, veins and / or heart of the human body are too tortuous, a sheath with a very small outer diameter and flexibility is required for installing the occluding device. At the same time, the occluding device is required to be able to easily enter the sheath and be easily released from the sheath. The occluding device should have the performance of being small in size after compression. The foldable and retractable skeleton 10 of the present application can be folded and easily entered into the sheath, and can also be easily stretched and released from the sheath. Specifically, when the intracavitary occluding device 100 reaches the lesion position through the conveyor and is released, the skeleton 10 compressed in the sheath will quickly restore its original shape due to the support of the memory alloy. At the same time, the flow-blocking membrane 20 also expands, and the flow-blocking membrane 20 fits tightly with the wall to complete the blood flow blockage of the intracavitary wall.

[0047] The skeleton 10 of the present application can be folded and retracted, and can also be used to block axially long organ channels, solving the technical problem that existing long organ channels cannot be blocked. The skeleton 10 of the present application can also be quickly extended after reaching the cavity, and the time required for blocking is relatively short, solving the technical problem that existing blocking devices take a long time to block the inner wall of the cavity. At the same time, the flow-blocking membrane 20 of the present application completely covers the skeleton 10, solving the technical problem that existing blocking effects are poor and there is a risk of recanalization.

[0048] In a specific embodiment, each protrusion 30 is fixedly connected to the corresponding first area 201, and a first pleated structure (not shown) is formed between adjacent first areas 201, so that the axial stretchable length of the flow-blocking film 20 is greater than or equal to the axial stretching length of the skeleton 10. Optionally, the protrusion 30 includes a convex top 30a, and the first area 201 includes a first connection position 201a corresponding to the convex top 30a, and the convex top 30a is fixedly connected to the first connection position 201a. In other embodiments, the connection position of the protrusion 30 and the corresponding first area 201 can also be other positions besides the convex top 30a, and this application is not limited here. In this way, as long as a larger area of ​​the flow-blocking film 20 is reserved on the adjacent two protrusions 30 connecting the recess 40, the flow-blocking film 20 can also completely cover the recess 40 along the surface of the fitting recess 40, thereby completely covering the skeleton 10, and when the skeleton 10 is stretched, it will not limit the stretching of the skeleton 10.

[0049] In another specific embodiment, each recess 40 is fixedly connected to a corresponding second region 202, and a second pleated structure 50 is formed between adjacent second regions 202, thereby ensuring that the axially stretchable length of the flow-blocking membrane 20 is greater than or equal to the axially stretchable length of the frame 10. Specifically, because the recess 40 is positioned lower than the protrusion 30, when the second region 202 of the flow-blocking membrane 20 is connected to the second section 401 of the recess 40, the pleated structure 50 effectively covers not only the protrusion 30 but also the recess 40.

[0050] Preferably, the recess 40 includes a recessed bottom 40a, and the second region 202 includes a second connection point 202a corresponding to the recessed bottom 40a. The recessed bottom 40a is fixedly connected to the second connection point 202a. In this case, the coverage area of ​​the pleated structure 50 is maximized, so that one pleated structure 50 completely covers one protrusion 30 and one recess 40, achieving optimal coverage. When the frame 10 is stretched, the flow-blocking film 20 does not restrict the stretching of the frame 10. In other embodiments, the connection between the recess 40 and the corresponding second region 202 can also be located at a position other than the recessed bottom 40a, and this application is not limited thereto.

[0051] In another specific embodiment, each protrusion 30 is fixedly connected to the corresponding first area 201 , and each recess 40 is also fixedly connected to the corresponding second area 202 .

[0052] That is, the protrusion 30 of the skeleton 10 is fixedly connected to the corresponding first area 201 of the baffle film 20; or the recess 40 of the skeleton 10 is fixedly connected to the corresponding second area 202 of the baffle film 20; or the protrusion 30 of the skeleton 10 is fixedly connected to the corresponding first area 201 of the baffle film 20, and the recess 40 of the skeleton 10 is also fixedly connected to the corresponding second area 202 of the baffle film 20. Thus, whether it is connected at the protrusion 30 or the recess 40, the skeleton 10 and the baffle film 20 can be connected. In this application, as long as the skeleton 10 and the baffle film 20 can be fixedly connected, whether the protrusion 30 is connected to the corresponding first area 201, the recess 40 is connected to the corresponding second area 202, or the protrusion 30 is connected to the corresponding first area 201 and the recess 40 is also connected to the corresponding second area 202, this application does not limit it.

[0053] Thus, a first pleated structure or a second pleated structure 50 is formed on the flow-blocking membrane 20, and the axially stretchable length of the flow-blocking membrane 20 is at least greater than or equal to the axially stretched length of the frame 10. When the frame 10 is axially stretched, the pre-stretching amount provided by the first pleated structure or the second pleated structure 50 allows the flow-blocking membrane 20 to conform to the axial stretching of the frame 10 without restricting the stretching of the frame 10, thereby ensuring that the flow-blocking membrane 20 better covers the frame 10 and improving the blocking effect of the flow-blocking membrane 20. Preferably, when the concave bottom 40a of the concave portion 40 of the frame 10 is fixedly connected to the second connecting portion 202a, the corresponding pleated structure 50 will be the longest, further not restricting the stretching of the frame 10, and further ensuring the covering effect of the flow-blocking membrane 20 on the frame 10.

[0054] The flow-blocking membrane 20 is an elastic membrane. Specifically, when the flow-blocking membrane 20 is an elastic membrane, the axially stretchable length of the flow-blocking membrane 20 will be greater than or equal to the axially stretchable length of the framework 10. The flow-blocking membrane 20 will not restrict the axial stretching of the framework 10, further ensuring the covering effect of the flow-blocking membrane 20 on the framework 10. In other words, the flow-blocking membrane 20 is elastic. When the occlusion device needs to be compressed and gripped in the delivery sheath, the inability of the flow-blocking membrane 20 to stretch will not cause the framework 10 to be unable to be compressed in the sheath. In other words, the flow-blocking membrane 20 and the mesh framework 10 can expand and contract together to fit into the sheath.

[0055] The shape of the baffle film is a regular wave fold, and the thickness of the baffle film is 0.04mm-0.08mm. When the skeleton 10 is stretched, the first fold structure or the second fold structure 50 of the baffle film 20 is stretched accordingly. When the first fold structure or the second fold structure 50 of the baffle film 20 is completely flattened, the baffle film 20 reaches its longest axial length, and the longest axial length of the baffle film 20 is greater than or equal to the length of the mesh skeleton 10 when it is axially stretched to the limit. Therefore, the baffle film 20 coated on the outer surface of the mesh skeleton 10 will not limit the axial stretching of the skeleton 10, so the occlusion device can be smoothly pressed and gripped in the delivery sheath. In addition, after being released, the baffle film returns to its folded shape. This baffle film 20 structure can increase the fit between the intracavitary occlusion device 100 and the wall, thereby increasing the blood flow blocking effect.

[0056] In the present application, since a first pleated structure or a second pleated structure 50 and an elastic flow-blocking membrane 20 are provided, the axially stretchable length of the flow-blocking membrane 20 is greater than or equal to the axial stretching length of the skeleton 10, thereby solving the technical problem that the axial stretchability of the existing flow-blocking membrane 20 is less than the axial stretchability of the skeleton 10, and the flow-blocking membrane 20 limits the axial stretching of the skeleton 10, making it difficult to compress the skeleton 10 in the sheath.

[0057] In this application, the curvature of the top of the protrusion 30 located at the two axial ends of the skeleton 10 is smaller than the curvature of the top of the protrusion 30 located between the two axial ends of the skeleton 10. In other words, the top of the protrusion 30 located at the two axial ends of the skeleton 10 is a flat surface with a smaller curvature, while the top of the protrusion 30 located between the two axial ends of the skeleton 10 is a curved surface with a larger curvature. The flat end surface of the protrusion 30 is primarily used to increase the contact area with the luminal tissue at the opening of the occlusion device, improving wall adhesion and enhancing the occlusion effect.

[0058] Optionally, the protrusion 30 located between the two axial ends of the skeleton 10 is an annular wave crest, the recess 40 is an annular wave trough, the top of the protrusion 30 is the peak of the annular wave crest, and the bottom of the recess 40 is the bottom of the annular wave trough.

[0059] In a specific embodiment, when the skeleton 10 is folded and compressed, the central axes of the protrusions 30 are equidistantly arranged, and the central axes of the recesses 40 are equidistantly arranged. That is to say, when the skeleton 10 is folded and compressed, the protrusions 30 are equidistantly arranged, and the recesses 40 are equidistantly arranged. When the protrusions 30 are equidistantly arranged, and the recesses 40 are equidistantly arranged, the force applied to the skeleton 10 will be more uniform, thus avoiding the technical problem of uneven force applied to the skeleton 10 due to greater or lesser force applied to some areas of the skeleton 10, and a reduced service life of the skeleton 10. In other embodiments, the central axes of the protrusions 30 may also be unequally arranged, and the central axes of the recesses 40 may also be unequally arranged. This method will make the use of the skeleton 10 more flexible, can be applied to more scenarios, and increase the scope of use of the skeleton 10.

[0060] The baffle film 20 is provided with a plurality of first alignment marks 60, which are provided on the first region 201 and are used to align the first region 201 with the first section 301. The baffle film 20 is provided with a plurality of second alignment marks 70, which are provided on the second region 202 and are used to align the second region 202 with the second section 401. In the present application, the first alignment marks 60 and the second alignment marks 70 are perpendicular to the axial direction of the skeleton 10. The first alignment marks 60 and the second alignment marks 70 can be marking points, marking lines, etc. formed by hot pressing. The first alignment marks 60 can align the first region 201 with the first section 301, thereby facilitating the alignment and connection of the first region 201 with the first section 301, thereby improving the accuracy of the connection; the second alignment marks 70 can align the second region 202 with the second section 401, thereby facilitating the alignment and connection of the second region 202 with the second section 401, thereby improving the accuracy of the connection.

[0061] In a specific embodiment, at least one first alignment mark 60 is fixedly connected to the corresponding first segment 301; and / or at least one second alignment mark 70 is fixedly connected to the corresponding second segment 401. In this embodiment, the fixed connection of the first alignment mark 60 to the first segment 301 allows for more precise alignment of the first region 201 with the first segment 301, thereby improving the accuracy of the connection between the first region 201 and the first segment 301. The fixed connection of the second alignment mark 70 to the second segment 401 allows for more precise alignment of the second region 202 with the second segment 401, thereby improving the accuracy of the connection between the second region 202 and the second segment 401.

[0062] Preferably, a second alignment mark 70 is provided on the second connection position 202a, and the second alignment mark is used to align the second connection position 202a with the recessed bottom 40a. In other words, the second alignment mark facilitates the alignment of the second connection position 202a with the recessed bottom 40a, making the alignment and connection of the second connection position 202a with the recessed bottom 40a more convenient and more precise.

[0063] Preferably, the second alignment mark 70 is fixedly connected to the concave bottom 40a. Thus, the second connection position 202a is precisely aligned with the concave bottom 40a through the fixed connection between the second alignment mark 70 and the concave bottom 40a.

[0064] The first alignment mark 60 and the second alignment mark 70 of the present application solve the problem of the difficulty in sewing the baffle film 20 onto the skeleton 10. Specifically, during the sewing process, on the one hand, when the suture needle acts on the skeleton 10 while passing through the baffle film 20, the skeleton 10 is easy to bend, which greatly increases the difficulty of sewing the baffle film 20. On the other hand, the skeleton 10 will return to its original shape after being released at the lesion site. In order to prevent the baffle film 20 from converging at a certain point on the outer surface of the skeleton 10 at this time, the baffle film 20 is often sewn along the peripheral wall of the skeleton 10. However, the good elasticity of the skeleton 10 and the good flexibility of the baffle film 20 make it difficult to sew the baffle film 20 on the peripheral wall of the skeleton 10. It is almost impossible to obtain a well-sewn intracavitary occlusion device 100 product. In addition, during the sewing process, the size of the pleated structure 50 formed by the folding of the baffle film 20 is difficult to control. Often, the length of the baffle film 20 after axial expansion is too small, so that the skeleton 10 cannot be fully stretched and the skeleton 10 cannot be transported. The first alignment mark 60 and the second alignment mark 70 of the present application can ensure a better suturing position, improve the suturing accuracy of the baffle film 20 on the surface of the skeleton 10, and better reserve the length of the baffle film 20 according to the elongation of the skeleton 10 after stretching to form a pleated structure 50, ensuring that the baffle film 20 better covers the skeleton 10 and improves the sealing effect of the baffle film 20.

[0065] The present invention provides a lotus-type intracavitary occlusion device 200 , comprising at least one of the above-mentioned intracavitary occlusion devices 100 .

[0066] See also Figure 6In a specific embodiment, the lotus-type intracavitary occlusion device 200 includes at least two of the above-mentioned intracavitary occlusion devices 100, and the proximal end of one intracavitary occlusion device 100 is connected to the distal end of the other intracavitary occlusion device 100 by a collar 110. Specifically, the intracavitary occlusion device 100 relies on the skeleton 10 to withstand the pressure of the inner cavity, and the flow-blocking membrane 20 bears almost no force, and the first bottom wall 106 and the second bottom wall 107 at both ends of the skeleton 10 mainly bear radial force. When the skeleton 10 is long, the middle part of the skeleton 10 is easily compressed due to the good elasticity of the metal wire, which will have an adverse effect on the sealing effect of the intracavitary occlusion device 100. On the other hand, when the inner cavity is very long, in order to improve the sealing effect of the intracavitary occlusion device 100, multiple intracavitary occlusion devices 100 will be released in the inner cavity. The lotus-type intracavitary occlusion device 200 of the present application connects the two intracavitary occlusion devices together through the collar 110 to form a lotus-type structure, specifically: The distal end of one intracavitary occlusion device 100 is connected to the proximal end of another intracavitary occlusion device 100 by means of a sleeve 110, and the metal wire at the distal end of one intracavitary occlusion device 100 and the metal wire at the proximal end of the other intracavitary occlusion device 100 are converged and welded in the sleeve 110. In this way, the radial force of the intracavitary occlusion device 100 can be increased, so that the peripheral wall of the intracavitary occlusion device 100 fits tightly with the inner wall of the inner cavity, thereby enhancing the sealing effect of the intracavitary occlusion device 100, and avoiding the tediousness and uncertainty of the operation caused by releasing multiple intracavitary occlusion devices 100 in the cavity. Of course, the number of intracavitary occlusion devices 100 connected end to end in this lotus-type intracavitary occlusion device 200 can be multiple, which is not limited here.

[0067] The present invention provides a sleeve-type intracavity blocking device 300 , comprising at least one of the above-mentioned intracavity blocking devices 100 .

[0068] See also Figure 7In a specific embodiment, the sleeve-type intracavitary blocking device 300 includes at least two of the above-mentioned intracavitary blocking devices 100, the two intracavitary blocking devices 100 being respectively a first intracavitary blocking device 400 and a second intracavitary blocking device 500, the axial length of the first intracavitary blocking device 400 being smaller than the axial length of the second intracavitary blocking device 500, the first intracavitary blocking device 400 being sleeved in the second intracavitary blocking device 500, the proximal end of the first intracavitary blocking device 400 being connected to the proximal end of the second intracavitary blocking device 500, and the distal end of the first intracavitary blocking device 400 being connected to the distal end of the second intracavitary blocking device 500 via an elastic member 140. Specifically, the proximal ends of the first intracavity blocking device 400 and the second intracavity blocking device 500 are directly connected via a common plug head 90. The distal end of the first intracavity blocking device 400 is provided with a first sleeve head 120, and the distal end of the second intracavity blocking device 500 is provided with a second sleeve head 130. The first sleeve head 120 and the second sleeve head 130 are connected via an elastic member 140. The sleeve-type intracavity blocking device 300 can be viewed as a shorter intracavity blocking device placed inside a longer intracavity blocking device. The metal wires at one end of the two intracavity blocking devices of the sleeve-type intracavity blocking device converge and are fixed to the plug head 90, which is provided with threads. The inner diameters of the two intracavitary occlusion devices are identical, and their peripheral walls are arranged to fit together. The first sleeve head 120 of the shorter first intracavitary occlusion device 400 is inside the second intracavitary occlusion device 500 with a longer length. The sleeve-type intracavitary occlusion device 300 can increase the radial force by having multiple intracavitary occlusion devices arranged inside and outside, thereby improving the interaction force between the flow-blocking membrane 20 of the sleeve-type intracavitary occlusion device and the inner wall of the inner cavity, enhancing the sealing effect, and avoiding the cumbersomeness and uncertainty of the operation caused by releasing multiple intracavitary occlusion devices in the cavity. The number of intracavitary occlusion devices built into the sleeve-type intracavitary occlusion device can be multiple. In addition, the first sleeve 120 of the shorter first intracavitary occluding device 400 is connected to the second sleeve 130 of the longer second intracavitary occluding device 500 by an elastic member 140. The elastic member 140 can be a spring. The elastic member 140 facilitates the contraction of the sleeve-type intracavitary occluding device 300 into the sheath. The elastic member 140 connects the two intracavitary occluding devices together to form an integral structure, which can improve the stability of the sleeve-type intracavitary occluding device 300.

[0069] The embodiments of the present invention are described in detail above. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core ideas. At the same time, for those skilled in the art, according to the ideas of the present invention, there may be changes in the specific implementation methods and application scopes. In summary, the contents of this specification should not be understood as limiting the present invention.

Claims

1. An intracavitary occlusion device, characterized in that: The invention relates to a flow-blocking film comprising a skeleton and a flow-blocking film covering the skeleton, wherein the skeleton comprises a plurality of first segments and second segments arranged alternately at intervals, the flow-blocking film comprises a plurality of first areas corresponding to each first segment and a second area corresponding to each second segment, at least one second segment is fixedly connected to the corresponding second area, the skeleton is foldable and retractable to form a protrusion at the position of the first segment and a recess at the position of the second segment, the protrusions and the recesses are arranged alternately at intervals in sequence; each recess is fixedly connected to the corresponding second area, and a second pleated structure is formed between adjacent second areas, so that the axial stretchable length of the flow-blocking film is greater than the axial stretchable length of the skeleton; the recess comprises a concave bottom, the second area comprises a second connection position corresponding to the concave bottom, and the concave bottom is fixedly connected to the second connection position; the flow-blocking film is provided with a plurality of first alignment marks, the plurality of first alignment marks are provided on the first area, and the first alignment marks are used to align the first area with the first segment; and / or the flow-blocking film is provided with a plurality of second alignment marks, the plurality of second alignment marks are provided on the second area, and the second alignment marks are used to align the second area with the second segment; The curvature of the top of the protrusion located at the two axial ends of the skeleton is smaller than the curvature of the top of the protrusion located between the two axial ends of the skeleton.

2. The intracavitary occlusion device according to claim 1, characterized in that: When the skeleton is folded and compressed, the central axes of the protruding parts are equidistantly arranged, and the central axes of the concave parts are equidistantly arranged.

3. The intracavitary occlusion device according to claim 1, characterized in that: The second alignment mark is provided on the second connection position, and the second alignment mark is used to align the second connection position with the concave bottom.

4. The intracavitary occlusion device according to claim 3, characterized in that: The second alignment mark is fixedly connected to the concave bottom.

5. The intracavitary occlusion device according to claim 1, characterized in that: The second section and the second region are fixedly connected by sutures.

6. The intracavitary occlusion device according to claim 1, characterized in that: The cross section of the skeleton is in the shape of a full moon, a crescent moon, a crescent moon or a waning moon.

7. The intracavitary occlusion device according to claim 1, characterized in that: The protrusion and the recess are in the shape of a semicircle, a square or a triangle.

8. The intracavitary occlusion device according to claim 1, characterized in that: The frame includes a first bottom wall and a second bottom wall that are oppositely arranged. The first sections and the second sections alternately form a peripheral wall. The first bottom wall and the second bottom wall are arranged at opposite ends of the peripheral wall.

9. A lotus-type intracavitary blocking device, characterized in that: The method comprises at least one intracavitary occlusion device according to any one of claims 1 to 8.

10. The lotus-type intracavitary blocking device according to claim 9, characterized in that: There are at least two intracavitary blocking devices, and the proximal end of one intracavitary blocking device is connected to the distal end of another intracavitary blocking device via a collar.

11. A sleeve-type intracavity blocking device, characterized in that: The method comprises at least one intracavitary occlusion device according to any one of claims 1 to 8.

12. The sleeve-type intracavitary occlusion device according to claim 11, characterized in that: There are at least two intracavity sealing devices, which are respectively a first intracavity sealing device and a second intracavity sealing device. The axial length of the first intracavity sealing device is smaller than the axial length of the second intracavity sealing device. The first intracavity sealing device is sleeved in the second intracavity sealing device. The first intracavity sealing device is connected to the proximal end of the second intracavity sealing device, and the distal end of the first intracavity sealing device is connected to the distal end of the second intracavity sealing device through an elastic member.

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