An intelligent, fully automatic, unmanned multi-probe Raman spectroscopy analysis device
Through intelligent, fully automatic unmanned multi-probe Raman spectroscopy analysis equipment, the problem of inconvenience in daily urine testing and single and inaccurate detection has been solved, and the rapid convenience of urine testing and the efficiency of multiple tests have been achieved.
Patent Information
- Application Number
- CN202010832820.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-08-18
- Publication Date
- 2025-01-21
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
In the prior art, daily urine detection is not convenient enough and the detection is single and inaccurate, so more health information cannot be detected in the urine.
Provide an intelligent fully automatic unmanned multi-probe Raman spectrum analysis equipment, including multiple sampling components, control components and detection components. The optical path connection between multiple sampling components is realized through a laser switch to achieve automated sampling and real-time spectroscopy. analyze.
It achieves rapid and convenient urine testing, can conduct multiple tests in real time and fully automatically, improves detection efficiency and reduces detection costs.
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Figure CN111965162B_ABST
Abstract
Description
Technical Field
[0001] The present application belongs to the technical field of medical detection equipment, and more specifically, to an intelligent, fully automatic, unmanned multi-probe Raman spectroscopy analysis device. Background Art
[0002] Raman spectroscopy is an analytical method based on the Raman scattering effect discovered by Indian scientist CV Raman. It analyzes the scattered spectrum with different frequencies from the incident light to obtain information on molecular vibration and rotation, and is applied to the study of molecular structure. Since the Raman spectroscopy analysis method does not require sample pretreatment and sample preparation, it avoids the generation of some errors. Therefore, it has the advantages of simple operation, short measurement time, and high sensitivity during the analysis process. At the same time, since the Raman spectrum of water is very weak and the spectrum is very simple, Raman spectroscopy is more suitable for studying trace components of liquid substances in a state close to nature.
[0003] Urine is a complex product excreted by human metabolism, rich in human health information; at the same time, urine is also the most convenient and direct physiological sample to reflect the health status of an individual. For example, the combined detection of trace urinary albumin and β2-microglobulin in urine is indicative for the early diagnosis of diabetic nephropathy. Usually, urine testing in hospitals is generally carried out using professional chemical analysis methods, with many test items and accurate results, but it is time-consuming, inconvenient and expensive. Only patients who really need to be tested will go to the hospital for urine testing, which is a therapeutic urine test. If ordinary people can perform urine testing on a daily basis, that is, daily healthy urine testing, then they can understand their physical health status at any time, dynamically and trend-wise, without having to wait until they are seriously ill to find problems. In other words, daily healthy urine testing is of great significance to improving the health index of individuals and society. To meet this demand, at present, urine testing for home use usually uses urine test strips, and then uses small electronic devices to identify the color changes of the urine test strips to judge the health status of individuals. However, the existing method of using test strips for home urine testing is neither hygienic nor convenient, and the test results are less accurate. In addition, the test items of the test strip test method are usually only a few simple items, such as whether the urine sugar is high, whether the uric acid is normal, etc. Therefore, this simple test method cannot detect more health information in urine, such as trace urine albumin and β2-microglobulin in urine, and its use is very limited. Summary of the invention
[0004] The purpose of the embodiments of the present application is to provide an intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis device to solve the technical problems in the prior art that daily urine testing is not convenient and the single test is inaccurate.
[0005] To achieve the above purpose, the technical solution adopted in this application is to provide an intelligent, fully automatic, unmanned multi-probe Raman spectroscopy analysis device, including:
[0006] Multiple sampling components, each of which includes a sampling device, a sensing module, and an identification module. The sensing module and the identification module are both arranged outside the sampling device. The sampling device is used to receive and temporarily store urine of the subject, the sensing module is used to sense the subject, and the identification module is used to identify the identity of the subject;
[0007] A control component, the control component includes a main control board, a communication module and a signal switching device, the main control board is connected to the cloud server through the communication module, the signal switching device has a first signal end and a plurality of second signal ends, the first signal end is connected to the main control board, and each second signal end is respectively connected to a sampling component;
[0008] The detection component includes a laser emission source, a laser switch, a Raman scattering processor, multiple temperature sensors, multiple laser probes and multiple Raman scattering collectors; the laser emission source and the Raman scattering collectors are both connected to the main control board; each sampling device is integrated with a temperature sensor, a laser probe and a Raman scattering collector; the laser emission source is connected to the optical path of the laser switch through an optical fiber, and each sampling component is connected to the optical path of the laser switch through an optical fiber; the laser emitted by the laser emission source irradiates the urine in the corresponding sampling device through one of the laser probes to form a Raman scattering signal, and the Raman scattering signal is collected by the corresponding Raman scattering collector and transmitted to the Raman scattering processor.
[0009] Optionally, the laser probe and Raman scattering collector in each sampling assembly form a detection light path through corresponding optical fibers, and the laser switch is used to control one of the detection light paths to connect with the main control board, the laser emission source and the Raman scattering processor.
[0010] Optionally, the laser switch includes an optical path switching component, the laser switch is connected to the main control board, and the optical path switching component is used to connect the laser emission source with the detection optical path corresponding to the line number information after receiving the line number information sent by the main control board via the line number device.
[0011] Optionally, in each sampling assembly, the sampling device includes a urinal, a sampling tube and a switch assembly, the urinal is used for the urine of the person being tested to flow into, the sampling tube is connected to the side wall of the urinal, and the sampling tube is provided with a switch assembly for controlling the opening and closing of the sampling tube;
[0012] Each second signal end is electrically connected to a switch component, a temperature detector, a sensing module and an identification module in a corresponding sampling component.
[0013] Optionally, the signal switching device includes a switching connector, a line number buffer, a line number queue, multiple downlink information buffers and multiple uplink information buffers; the multiple downlink information buffers are electrically connected to the main control board, and the multiple uplink information buffers are electrically connected to the multiple sampling components one by one; the switching connector is electrically connected to the main control board, the downlink information buffer, the uplink information buffer, the line number queue and the line number buffer, respectively; the line number queue is electrically connected to the downlink information buffer, the uplink information buffer and the line number buffer, respectively.
[0014] Optionally, the sampling tube has an upper opening and a lower opening located below the upper opening, and both the upper opening and the lower opening are connected to the inner cavity of the urine tube;
[0015] The switch assembly includes a urine inlet magnetic valve switch arranged at the upper end opening and a urine magnetic valve switch arranged inside the sampling tube. The urine inlet magnetic valve switch and the urine magnetic valve switch are both electrically connected to the main control board through a signal switching device.
[0016] The sampling tube includes a first tube section, a second tube section and a third tube section which are connected in sequence; the first tube section is arranged to be tilted outward and downward compared with the axial direction of the urine tube, the second tube section is arranged horizontally, and the third tube section is arranged to be tilted downward in the direction toward the urine tube;
[0017] The laser switch is connected to the laser probe optical path through optical fiber. The detection end of the laser probe extends into the second pipe section from the upper side wall of the second pipe section. The other end of the laser probe is connected to the Raman scattering collector through optical fiber. The Raman scattering collector is then connected to the Raman scattering processor through the laser switch.
[0018] Optionally, the inner diameter of the first pipe section is smaller than the inner diameter of the second pipe section.
[0019] The detection end of the thermometer extends into the second pipe section from the upper side wall of the second pipe section; the detection end of the laser probe and the detection end of the thermometer are both spaced apart from the urine liquid surface in the second pipe section;
[0020] The urine magnetic valve switch is located in the second pipe section adjacent to the third pipe section, and there is a distance between the top of the urine magnetic valve switch and the top of the inner wall surface of the second pipe section.
[0021] Optionally, an inner convex portion is provided on the inner wall surface of the urinal, and the top end surface of the inner convex portion is inclined downward in the direction toward the center of the cross section of the urinal; after the inner convex portion is passed through one side of the sampling tube, the upper end opening is exposed on the top end surface of the inner convex portion.
[0022] Optionally, the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment also includes a flush switch for flushing the sampling tube. The flush switch is arranged on the urinal and is electrically connected to the main control board through a signal switching device.
[0023] Optionally, the recognition module includes a face recognizer and a card reader, and the sensing module includes a human infrared sensor. The face recognizer and the card reader are connected to the cloud server information through a signal switching device, a main control board, and a communication module in sequence, and the human infrared sensor is connected to the main control board through a signal switching device.
[0024] The intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis equipment also includes a positioning module installed on the sampling device. The positioning module is connected to the cloud server information via a signal switching device, a main control board, and a communication module in sequence.
[0025] The beneficial effect of the intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis equipment provided by the present application is that: compared with the prior art, since the intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis equipment is provided with multiple sampling components, control components and detection components, wherein the main control board in the control component can realize the intelligent, fully automatic sampling control of a certain sampling component among the multiple sampling components through the signal switching device, and at the same time, the detection component can also realize the optical path connection with different sampling components through the laser switcher; therefore, the intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis equipment can realize the automatic control of multiple sampling components, so that multiple sampling components can share a control device and a laser emission source and a Raman scattering processor, etc., not only can it realize the real-time and fully automatic operation of processes such as on-site sampling, on-the-spot inspection, and real-time spectral analysis, making the entire urine detection process very quick and convenient, but also can greatly reduce the cost of the entire device with multiple sampling components, so as to achieve the purpose of reducing the detection cost while improving the detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.
[0027] Figure 1 A functional module diagram of an intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis device provided in one embodiment of the present application;
[0028] Figure 2 for Figure 1 A functional module diagram of a sampling component, a control component and a detection component;
[0029] Figure 3 for Figure 2 Functional module diagram of the signal switching device, sampling component and main control board;
[0030] Figure 4 A schematic diagram of the structure of an intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis device provided in one embodiment of the present application;
[0031] Figure 5 A schematic structural diagram of an intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis device provided in another embodiment of the present application;
[0032] Figure 6 for Figure 1 Functional module diagram of the laser switcher, main control board, and detection component.
[0033] Description of Figure Numbers:
[0034]
[0035] DETAILED DESCRIPTION
[0036] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.
[0037] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.
[0038] It should also be noted that the directional terms such as left, right, up and down in the embodiments of the present application are merely relative concepts or are based on the normal use status of the product, and should not be considered as restrictive.
[0039] Embodiments of the present application are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present application, and should not be construed as limiting the present application.
[0040] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.
[0041] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.
[0042] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.
[0043] The embodiment of the present application provides an intelligent, fully automatic, unmanned multi-probe Raman spectroscopy analysis device.
[0044] See also Figure 1 , Figure 2 and Figure 4In one embodiment, the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment includes a plurality of sampling components, a control component and a detection component. Among the plurality of sampling components, each sampling component includes a sampling device 100, a sensing module 210, and an identification module 220. The sensing module 210 and the identification module 220 are both arranged outside the sampling device 100. The sampling device 100 is used to receive and temporarily store the urine of the person being tested, the sensing module 210 is used to sense the person being tested, and the identification module 220 is used to identify the identity of the person being tested. The control component includes a main control board 410, a communication module 420 and a signal switching device 430. The main control board 410 is connected to the cloud server 700 through the communication module 420. The signal switching device 430 has a first signal end and a plurality of second signal ends. The first signal end is connected to the main control board 410, and each second signal end is connected to a sampling component. The detection component includes a laser emission source 320, a laser switch 380, a Raman scattering processor 350, multiple temperature sensors 310, multiple laser probes 330 and multiple Raman scattering collectors 340; the laser emission source 320 and the Raman scattering collectors 340 are both connected to the main control board 410; each sampling device 100 is integrated with a temperature sensor 310, a laser probe 330 and a Raman scattering processor 350; the laser emission source 320 is optically connected to the laser switch 380 through an optical fiber 360, and each sampling component is optically connected to the laser switch 380 through an optical fiber 360; the laser emitted by the laser emission source 320 irradiates the urine in the corresponding sampling device 100 through one of the laser probes 330 to form a Raman scattering signal, and the Raman scattering signal is collected by the corresponding Raman scattering collector 340 and transmitted to the Raman scattering processor 350.
[0045] Based on this structural design, in this embodiment, since the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis device is provided with multiple sampling components, control components and detection components, the main control board 410 in the control component can realize the intelligent fully automatic sampling control of a certain sampling component among the multiple sampling components through the signal switching device 430, and at the same time, the detection component can also realize the optical path connection between different sampling components through the laser switcher 380. Therefore, the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis device can realize the automatic control of multiple sampling components, so that multiple sampling components can share a control device and a laser emission source 320 and a Raman scattering processor 350, etc., not only can it realize the real-time and fully automatic operation of the processes such as on-site sampling, on-the-spot inspection, and real-time spectral analysis, making the entire urine detection process very fast and convenient, but also can greatly reduce the cost of the entire device with multiple sampling components, so as to achieve the purpose of reducing the detection cost while improving the detection efficiency.
[0046] It should be noted here that the intelligent fully automatic unmanned multi-probe Raman spectroscopy analysis equipment can be applied to home detection. For example, a sampling assembly can be set in multiple bathrooms, and then multiple sampling assemblies of a household share a control device and a laser emission source 320 and a Raman scattering processor 350, etc. Of course, the equipment can also be applied to places such as hospitals or physical examination institutions. Specifically, the urine tube 110 is the sewage pipe of the urinal, that is, the upper end of the urine tube 110 is connected to the bottom interface of a conventional urinal; in order to realize the corresponding data processing and control functions, the main control board 410 is mainly integrated with a central processing unit and related electrical components, and the communication module 420 can be integrated on the main control board 410 or set separately. Specifically, the central processor on the main control board 410 can be electrically connected with the temperature detector 310, the sampling device 100, the sensing module 210 and the identification module 220 through the signal line and the signal switching device 430 to realize the transmission interaction and operation control of data information, so that the control selection of the sampling component, the acquisition of the information of the detected person, the urine standard control and the urine sampling process can be easily realized. The laser emission source 320, the laser switch 380, the laser probe 330, the Raman scattering collector 340 and the Raman scattering processor 350 can be optically transmitted through the optical fiber 360, and then the Raman scattering processor 350 transmits the processed information to the central processor through the internal communication method, and then the central processor uploads the information to the cloud server 700 through the communication module 420 for storage, processing and analysis, thereby realizing the processes of urine detection, urine spectrum analysis, information upload storage and analysis. In addition, the device also includes a pluggable and mobile power supply 500, which can supply power to various related components. The power supply method can be to directly connect the functional components through wires to supply power, or to indirectly connect the main control board 410 to the related functional components to supply power.
[0047] See also Figure 1 and Figure 2 as well as Figure 6 In this embodiment, the laser probe 330 and the Raman scattering collector 340 in each sampling assembly form a detection optical path through the corresponding optical fiber 360, and the laser switch 380 is used to control one of the detection optical paths to be connected to the main control board 410, the laser emission source 320 and the Raman scattering processor 350. The laser switch 380 includes an optical path switching component (not shown), the laser switch 380 is connected to the main control board 410, and the optical path switching component is used to connect the laser emission source 320 with the detection optical path corresponding to the line number information after receiving the line number information sent by the main control board 410 through the line number device 381.
[0048] Specifically, when sampling starts in a certain sampling component, that is, when the central processor on the main control board 410 detects that the temperature on a certain optical path corresponding to the sampling component is higher than the ambient temperature value and stabilizes, the central processor will transmit the line number of the optical path to the laser switch 380, and then the laser switch 380 will connect the optical path corresponding to the line number and send a ready information to the central processor; then, after the central processor receives the information that the optical path is ready from the laser switch 380, it will control the laser emission source 320 to emit laser, and the laser is connected to the laser switch 380 through the laser switch 380. The optical path reaches the laser probe 330 of the corresponding line number to irradiate the urine temporarily stored in the sampling device 100 to generate a Raman scattering signal. At the same time, the central processing unit also sends the corresponding line number to the Raman scattering processor 350; then, the Raman scattering collector 340 transmits the collected Raman scattering signal to the Raman scattering processor 350 for processing through the optical path connected to the laser switch 380 again; finally, the Raman scattering processor 350 sends the processed information to the central processing unit according to the corresponding line number, thus completing a urine automatic detection process.
[0049] See also Figures 1 to 4 Specifically in this embodiment, in each sampling component, the sampling device 100 includes a urinal 110, a sampling tube 120 and a switch component 130. The urinal 110 is used for the urine of the person being tested to flow into, the sampling tube 120 is connected to the side wall of the urinal 110, and the sampling tube 120 is provided with a switch component 130 for controlling the opening and closing of the sampling tube 120; each second signal end is electrically connected to the switch component 130, the temperature detector 310, the sensing module 210 and the identification module 220 in a corresponding sampling component.
[0050] Specifically, Figure 3 As shown, the signal switching device includes a switching connector 431, a line number buffer 432, a line number queue 433, multiple downlink information buffers 434 and multiple uplink information buffers 435; the multiple downlink information buffers 434 are electrically connected to the main control board respectively, and the multiple uplink information buffers 435 are electrically connected to the multiple sampling components one by one; the switching connector 431 is electrically connected to the main control board, the downlink information buffer 434, the uplink information buffer 435, the line number queue 433, and the line number buffer 432 respectively; the line number queue 433 is electrically connected to the downlink information buffer 434, the uplink information buffer 435 and the line number buffer 432 respectively.
[0051] Taking the first sampling component to the nth sampling component as an example (n is a positive integer), the working principle of the signal switching device 430 is as follows:
[0052] In the first step, when the device is powered on for the first time, the central processing unit on the main control board 410 clears the first downlink information buffer 434 to the nth downlink information buffer 434, the line number queue 433, the line number buffer 432, the first uplink information buffer 435, the nth uplink information buffer 435, etc.
[0053] In the second step, when the device starts working, all the information uploaded by the devices in the first sampling component is stored in the first upload information buffer 435, and at the same time, the first line number is sent to the line number queue 433 and waits to be read; similarly, all the information uploaded by the devices in the nth sampling component is stored in the nth upload information buffer 435, and at the same time, the nth line number is sent to the line number queue 433 and waits to be read.
[0054] In the third step, the CPU stores the information to be transmitted in the first transmission information buffer 434 and the nth transmission information buffer 434 according to the corresponding line number, and at the same time, sends the corresponding line number (such as 1, 2, 3, etc.) to the line number queue 433 through the signal line of the line number buffer 432 and waits for reading. At this time, whether it is uploading information or transmitting information, the line number queue 433 can only insert the line number that does not exist according to the line number size. If there is an existing line number, it does not need to be inserted into the line number queue.
[0055] In the fourth step, the signal switching device 430 reads the line number in the line number queue 433 into the line number buffer 432 and deletes the corresponding line number in the line number queue 433 .
[0056] In the fifth step, the signal switching device 430 reads the line number in the line number buffer 432, reads the information in the first upload information buffer 435 and the nth upload information buffer 435 on the line number according to the line number and executes it through the central processor. At the same time, reads and sends all the information of the line number in the first downlink information buffer 434 and the nth downlink information buffer 434 according to the line number. After the execution is completed, the line number is deleted from the line number buffer 432; similarly, the next line number is executed. Until the current line number buffer is empty. Then, the signal switching device 430 repeats the fourth and fifth steps in a loop.
[0057] Refer to Figure 4In this embodiment, the sampling tube 120 has an upper opening 124 and a lower opening 125 located below the upper opening 124, and both the upper opening 124 and the lower opening 125 are connected to the inner cavity of the urine tube 110. The switch assembly 130 includes a urine inlet magnetic valve switch 131 provided at the upper opening 124 and a urine magnetic valve switch 132 provided inside the sampling tube 120, and both the urine inlet magnetic valve switch 131 and the urine magnetic valve switch 132 are electrically connected to the main control board 410 through the signal switching device 430. In this way, the main control board 410 can realize the precise control of the sampling device 100 to be sampled and tested through the signal switching device 430, especially the control of each magnetic valve switch in the sampling device 100, thereby realizing the unmanned automation of the sampling process. Specifically, the urine inlet magnetic valve switch 131 is mainly used for opening and closing control of the upper end opening 124 of the sampling tube 120 , and the urine magnetic valve switch 132 is mainly used for controlling the retention and release of urine in the sampling tube 120 . In actual use, after the urine of the person being tested enters the sampling tube 120 through the urinary tube 110, the thermometer 310, such as the infrared thermometer 311, will start to measure the temperature of the urine in the sampling tube 120, and the central processing unit on the main control board 410 will receive the continuous temperature measurement information sent by the infrared thermometer 311. When the central processing unit detects that the temperature is higher than the ambient temperature and continues to stabilize at a predetermined value, it will send a closing instruction to the urine inlet magnetic valve switch 131 and the urine magnetic valve switch 132. After the two switches are closed, the urine will remain in the transparent sampling tube 120. In this way, it can be ensured that the urine tested in the sampling tube 120 is the middle section of urine that meets the medical sampling standards, and the urine is in a stable state, which can ensure the uniformity of urine testing standards and reduce errors to improve the accuracy of urine testing.
[0058] like Figure 4 As shown, in this embodiment, the sampling tube 120 includes a first tube section 121, a second tube section 122 and a third tube section 123 connected in sequence; the first tube section 121 is tilted outward and downward compared to the axial direction of the urinal tube 110, the second tube section 122 is horizontally arranged, and the third tube section 123 is tilted downward in the direction toward the urinal tube 110, so that it is conducive to the reception and temporary storage of urine, and the sampling tube 120 is usually a transparent tube that is convenient for observing the urine liquid level and facilitating laser irradiation detection. Of course, in other embodiments, the lower end opening 125 of the sampling tube 120 can also be connected to other pipes for urine discharge, but in this embodiment, the bent sampling tube 120 is integrated and connected to the urinal tube 110, and the upper end opening 124 and the lower end opening 125 are both connected to the inner cavity of the urinal tube 110. The design can avoid the opening of redundant pipes, so that the sampling device 100 has a simpler structure and occupies less space. In addition, in the case of Figure 5In another embodiment shown, in addition to the aforementioned component structure, a slag screen 140 is also covered at the entrance of the urinal 110. The slag screen 140 mainly serves to isolate impurities irrelevant to urine detection, thereby further improving the accuracy of urine detection of the device.
[0059] In this embodiment, if Figure 4 As shown, the laser switch 380 is connected to the laser probe 330 optical path through the optical fiber 360, the detection end of the laser probe 330 extends from the upper side wall of the second pipe section 122 into the second pipe section 122, and the other end of the laser probe 330 is connected to the Raman scattering collector 340 through the optical fiber 360; the Raman scattering collector 340 is further connected to the Raman scattering processor 350 through the laser switch 380. The detection end of the thermometer 310 extends from the upper side wall of the second pipe section 122 into the second pipe section 122; the detection end of the laser probe 330 and the detection end of the thermometer 310 are both spaced apart from the urine liquid surface in the second pipe section 122; at the same time, the urine magnetic valve switch 132 is located in the second pipe section 122 adjacent to the third pipe section 123, and there is a distance between the top of the urine magnetic valve switch 132 and the top of the inner wall of the second pipe section 122. Here, the thermometer 310 is preferably a non-contact infrared thermometer 311 to avoid contact with urine as much as possible. Of course, in other embodiments, the thermometer 310 can also be an immersion contact thermometer, etc., which is not limited here. Specifically, the Raman scattering collector 340 and the laser probe 330 are placed and fixed perpendicular to the second pipe section 122, and the infrared thermometer 311 is placed above the second pipe section 122 so that the temperature can be continuously detected. The detection ends of the laser probe 330 and the infrared thermometer 311 are basically flush with or slightly protruding from the inner wall of the second pipe section 122, so as to avoid urine contamination while realizing the detection function, thereby avoiding the occurrence of poor testing caused by sample contamination.
[0060] Specifically, the inner diameter of the first pipe section 121 is smaller than the inner diameter of the second pipe section 122. Preferably, the distance between the top of the urine magnetic valve switch 132 and the top of the inner wall surface of the second pipe section 122 is 1 / 4 to 1 / 2 of the inner diameter of the second pipe section 122, and in this embodiment, the distance can be further preferably 1 / 4, that is, the height of the urine magnetic valve switch 132 is preferably 3 / 4 of the inner diameter of the second pipe section 122. It can be understood that since the height of the urine magnetic valve switch 132 is 3 / 4 of the inner diameter of the second pipe section 122, when the urine magnetic valve switch 132 is closed, only 3 / 4 of the pipe opening of the second pipe section 122 can be closed, and it will not be completely closed, that is, when the urine is excessive, it will flow out from the top of the urine magnetic valve switch 132, and the urine level in the second pipe section 122 will not exceed 3 / 4 of its inner diameter. In this way, the top of the inner wall surface of the second pipe section 122 will not contact the urine, thereby ensuring that the top area is not contaminated by urine and reducing inaccurate detection information caused by contamination of the top of the second pipe section 122.
[0061] For further information, see Figure 4 In this embodiment, in order to facilitate sampling of the sampling tube 120, an inner convex portion 111 is convexly provided on the inner wall surface of the urine tube 110. The inner convex portion 111 may be annular or may be formed by a plurality of convex blocks arranged at intervals along the circumferential direction of the inner wall surface of the urine tube 110, and the inner convex portion 111 is preferably provided at the lower middle part of the urine tube 110. Here, the top end surface of the inner convex portion 111 is inclined downward in the direction toward the center of the cross section of the urine tube 110; after the inner convex portion 111 is passed through one side of the sampling tube 120, the upper end opening 124 is exposed on the top end surface of the inner convex portion 111. In this way, since the top end surface of the inner convex portion 111 is inclined, the urine flowing from the urine tube 110 will stay on the top end surface of the inner convex portion 111 for a short time and will not flow away immediately, and then the urine will flow into the sampling tube 120 from the upper end opening 124 of the sampling tube 120.
[0062] See also Figure 1 and Figure 2In this embodiment, the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis device also includes a flushing switch for flushing the sampling tube 120. The flushing switch is arranged on the urine tube 110 and is electrically connected to the main control board 410 through the signal switching device 430. In this way, the flushing switch on the corresponding sampling device 100 can be accurately controlled by the signal switching device 430 to achieve the purpose of automatically flushing the corresponding sampling tube 120. Here, the flushing switch can be preferably a magnetic valve switch and connected to the water pipe, which can realize automatic cleaning of the sampling tube 120 to ensure that the current urine is not contaminated by the previous urine and improve the detection accuracy. Specifically, when the sensing module 210, such as the human infrared sensor, senses the presence of a person being detected, it will send an open signal to the flush switch to flush the sampling tube 120 for the first time, and send a close signal to close the flush switch after a preset time, such as 3 seconds; when the detection is completed and the human infrared sensor senses that the person being detected has left, it will send an open signal to the flush magnetic valve switch again through the main control board 410 to flush the sampling tube 120 for the second time, and send a close signal after a preset time; during the two flushing processes, the clean water used for flushing enters from the upper opening 124 of the sampling tube 120, and flows out from the lower opening 125 after automatically cleaning the sampling tube 120.
[0063] See also Figure 1 and Figure 2In this embodiment, the recognition module 220 includes a face recognizer and a card reader, and the sensing module 210 includes a human infrared sensor. The face recognizer and the card reader are connected to the cloud server 700 through the signal switching device 430, the main control board 410 and the communication module 420 in turn, and the human infrared sensor is connected to the main control board 410 through the signal switching device 430; of course, in other embodiments, the recognition module 220 can also be other types of identity identifiers, and the sensing module 210 is not limited to the human infrared sensor; but in this embodiment, since the device is placed in a non-clean environment for a long time, it is inevitable to be contaminated, and it is preferred to use human infrared sensors, face recognizers, NFC (Near Field Communication) card readers and other devices for contactless information acquisition, so that the person being detected avoids the risk of contact contamination. Specifically, since the NFC card information or face recognition information of the detected person has been read before the urine test, when the test report is generated, the test result and the identity of the detected person have been automatically associated, so that the automatic matching between the test report and the detected person can be achieved. After the detection is completed, this device can automatically store the test result in the cloud server 700 through the communication module 420, so that the detected person can view the test report anytime and anywhere, which is very convenient. In addition, in the present embodiment, a face recognition device can also be used to identify whether it is a registered user. If it is not a registered user, urine analysis is not performed. If it is a registered user, urine analysis is performed.
[0064] In addition, in this embodiment, the intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment also includes a positioning module 800 installed on the sampling device 100, and the positioning module 800 is connected to the cloud server 700 information through the signal switching device 430, the main control board 410 and the communication module 420 in turn. Here, the communication module preferably uses 5G network communication. Of course, in other embodiments, it can also be WIFI network communication or other network communication. It can be understood that after setting the positioning module 800, through the GPS positioning information, the user can find the device closest to him from the mobile phone for urine testing; the operator can also use the positioning module 800 to determine whether the equipment has been moved; of course, if the equipment fails, the maintenance personnel can also use the GPS positioning information to locate the faulty equipment for maintenance.
[0065] Finally, based on the above technical solutions, and referring to Figures 1 to 4 The entire operation process of this intelligent fully automatic unmanned multi-probe Raman spectroscopy analysis equipment is as follows:
[0066] The first stage is the preparation stage of the device. First, when the power supply 500 is turned on for the first time, the positioning module 800 sends the positioning information of a sampling component selected by the test person to the cloud server 700 through the communication module 420 and the 5G network communication; then, the central processor on the main control board 410 selects the corresponding signal channel to send information through the signal switching device 430 to open the urine inlet magnetic valve switch 131 and close the urine magnetic valve switch 132; at the same time, the central processor also sends a start continuous temperature measurement signal to the infrared thermometer 311 through the signal switching device 430, and the infrared thermometer 311 transmits the measured temperature information to the central processor through the signal switching device 430, and sets the value to be saved as the ambient temperature value, then, the central processor sends a stop continuous temperature measurement signal to the infrared thermometer 311 through the signal switching device 430, and the infrared thermometer 311 stops measuring temperature; at the same time, a stop signal is sent to the face recognizer through the signal switching device 430, and a closing message is sent to the flush switch at the same time, at this time, the device enters a normal working state.
[0067] The second stage is the formal working stage of the device. When the human infrared sensor on the sampling component senses the presence of a person to be detected, the central processor on the main control board 410 will send an open signal to the flush switch through the signal switching device 430 to flush the sampling tube 120 for the first time, and send a close signal to close the flush switch after a preset time, such as 3 seconds. At the same time, the central processor sends an open signal to the face recognizer through the signal switching device 430 for face recognition, or the person to be detected actively swipes the NFC card to read the NFC card information, which will be sent to the central processor through the signal switching device 430; after receiving the information, the central processor can compare the face recognition information or NFC card information with the registered users stored in the cloud server 700 through the communication module 420 and the 5G network communication; if it is a non-registered user, no urine test will be performed, and if it is a registered user, the information will be fed back to the central processor; then, the central processor sends a continuous temperature measurement signal to the infrared thermometer 311 through the signal switching device 430 for continuous temperature measurement. When the person being tested starts to urinate, the urine will gather at the bottom of the urinal and enter the urinal tube 110, and then fall on the inclined top end surface of the inner convex part 111. At this time, the urine inlet magnetic valve switch 131 is in an open state, and the urine can automatically enter the transparent sampling tube 120 under the action of gravity. In the process of urine entering the sampling tube 120, the infrared thermometer 311 will continuously measure the temperature and send the temperature measurement result to the central processor through the signal switching device 430. When the central processor detects that the temperature higher than the ambient temperature value is stable, it will send a related signal through the signal switching device 430 to simultaneously close the urine inlet magnetic valve switch 131 and the urine magnetic valve switch 132. At the same time, the central processing unit will send a shutdown signal to the infrared thermometer 311 through the signal switching device 430 to stop the temperature measurement, and control the laser emission source 320 to emit the laser; the laser reaches the laser probe 330 through the optical fiber 360 and the laser switch 380, and then irradiates the urine in the transparent sampling tube 120 to form a Raman scattered light signal, which will be collected by the Raman scattering collector 340 and transmitted to the Raman scattering processor 350 (the Raman scattering processor 350 can be integrated on the main control board 410 or set separately) through the optical fiber 360 and the laser switch 380; then, the Raman scattering processor 350 converts these light signals into digital information and transmits them to the central processing unit; then, the central processing unit communicates with the 5G network through the communication module 420, and can quickly transmit this information to the cloud server 700 for storage and analysis.
[0068] After the detection is completed, the central processor will send a signal through the signal switching device 430 to open the urine inlet magnetic valve switch 131 and the urine magnetic valve switch 132, so that the urine in the sampling tube 120 will flow out from the lower end opening 125 of the sampling tube 120, i.e., the urine outlet, under the action of gravity. When the human infrared sensor senses that the person being detected has left, it will send an open signal to the flush switch through the central processor of the main control board 410 to flush the sampling tube 120 for the second time, and send a close signal after a preset time, such as 3 seconds; the clean water of the second flush enters from the upper end opening 124 of the sampling tube 120, i.e., the urine inlet, automatically cleans the sampling tube 120, and then flows out from the lower end opening 125 of the sampling tube 120, i.e., the urine outlet. In this way, a urine analysis of an intelligent, fully automatic, unmanned multi-probe Raman spectroscopic analysis device is completed, thereby achieving the real-time nature of urine detection. Of course, this process is only the operation process of one sampling component. Under the action of the signal switching device 430 and the laser switch 380 of this equipment, multiple sampling components can also be operated sequentially or simultaneously, and the operation process of each sampling component is consistent with the above.
[0069] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application should be included in the protection scope of the present application.
Claims
1. An intelligent fully automatic unmanned multi-probe Raman spectroscopy analysis device, characterized in that: include: A plurality of sampling components, each of which comprises a sampling device, a sensing module, and an identification module, wherein the sensing module and the identification module are both arranged outside the sampling device, the sampling device is used to receive and temporarily store urine of a subject, the sensing module is used to sense a subject, and the identification module is used to identify the identity of the subject; A control component, the control component comprising a main control board, a communication module and a signal switching device, the main control board is connected to the cloud server through the communication module, the signal switching device has a first signal end and a plurality of second signal ends, the first signal end is connected to the main control board, and each of the second signal ends is respectively connected to one of the sampling components; A detection component, the detection component includes a laser emission source, a laser switch, a Raman scattering processor, a plurality of temperature detectors, a plurality of laser probes and a plurality of Raman scattering collectors; the laser emission source and the Raman scattering collectors are both connected to the main control board; each of the sampling devices is integrated with a temperature detector, a laser probe and a Raman scattering collector; the laser emission source is connected to the optical path of the laser switch through an optical fiber, and each of the sampling components is connected to the optical path of the laser switch through an optical fiber; the laser emitted by the laser emission source irradiates the urine in the corresponding sampling device through one of the laser probes to form a Raman scattering signal, and the Raman scattering signal is collected by the corresponding Raman scattering collector and transmitted to the Raman scattering processor; The temperature detector is a non-contact infrared temperature detector or an immersion contact temperature detector.
2. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 1, characterized in that: The laser probe and the Raman scattering collector in each sampling assembly form a detection light path through corresponding optical fibers, and the laser switch is used to control one of the detection light paths to connect with the main control board, the laser emission source and the Raman scattering processor.
3. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 2, characterized in that: The laser switch includes an optical path switching component, which is connected to the main control board. The optical path switching component is used to connect the laser emission source with the detection optical path corresponding to the line number information after receiving the line number information sent by the main control board via the line number device.
4. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 2, characterized in that: In each of the sampling components, the sampling device includes a urine tube, a sampling tube and a switch component. The urine tube is used for the urine of the subject to flow into, the sampling tube is connected to the side wall of the urine tube, and the sampling tube is provided with a switch component for controlling the opening and closing of the sampling tube; Each of the second signal ends is electrically connected to the switch component, the temperature detector, the sensing module and the identification module in a corresponding sampling component.
5. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 1, characterized in that: The signal switching device includes a switching connector, a line number buffer, a line number queue, multiple downlink information buffers and multiple uplink information buffers; the multiple downlink information buffers are electrically connected to the main control board respectively, and the multiple uplink information buffers are electrically connected to multiple sampling components one by one; the switching connector is electrically connected to the main control board, the downlink information buffer, the uplink information buffer, the line number queue, and the line number buffer respectively; the line number queue is electrically connected to the downlink information buffer, the uplink information buffer and the line number buffer respectively.
6. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 4, characterized in that: The sampling tube has an upper opening and a lower opening located below the upper opening, and both the upper opening and the lower opening are connected to the inner cavity of the urine tube; The switch assembly comprises a urine inlet magnetic valve switch arranged at the upper end opening and a urine magnetic valve switch arranged inside the sampling tube, and both the urine inlet magnetic valve switch and the urine magnetic valve switch are electrically connected to the main control board through the signal switching device; The sampling tube comprises a first tube section, a second tube section and a third tube section which are connected in sequence; the first tube section is arranged to be tilted outward and downward compared with the axial direction of the urine tube, the second tube section is arranged horizontally, and the third tube section is arranged to be tilted downward in the direction toward the urine tube; The laser switch is connected to the optical path of the laser probe through the optical fiber. The detection end of the laser probe extends into the second pipe section from the upper side wall of the second pipe section. The other end of the laser probe is connected to the Raman scattering collector through the optical fiber. The Raman scattering collector is then connected to the Raman scattering processor through the laser switch.
7. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 6, characterized in that: The inner diameter of the first pipe section is smaller than the inner diameter of the second pipe section; The detection end of the thermometer extends from the upper side wall of the second pipe section into the second pipe section; the detection end of the laser probe and the detection end of the thermometer are both spaced apart from the urine liquid surface in the second pipe section; The urine magnetic valve switch is located in the second pipe section adjacent to the third pipe section, and there is a distance between the top of the urine magnetic valve switch and the top of the inner wall of the second pipe section.
8. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 6, characterized in that: An inner convex portion is convexly provided on the inner wall surface of the urinal, and the top end surface of the inner convex portion is inclined downward in the direction toward the cross-sectional center of the urinal; after the inner convex portion is passed through one side of the sampling tube, the upper end opening is exposed on the top end surface of the inner convex portion.
9. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment according to claim 4, characterized in that: The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment also includes a flush switch for flushing the sampling tube. The flush switch is arranged on the urinal and is electrically connected to the main control board through the signal switching device.
10. The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis device according to any one of claims 1 to 9, characterized in that: The recognition module includes a face recognizer and a card reader, the sensing module includes a human infrared sensor, the face recognizer and the card reader are connected to the cloud server information through the signal switching device, the main control board and the communication module in sequence, and the human infrared sensor is connected to the main control board through the signal switching device; The intelligent fully automatic unmanned multi-probe Raman spectroscopic analysis equipment also includes a positioning module installed on the sampling device, and the positioning module is connected to the cloud server information through the signal switching device, the main control board and the communication module in sequence.
Citation Information
Patent Citations
Intelligent full-automatic unmanned multi-probe Raman spectrum analysis equipment
CN212341011U