A semi-isolated arteriovenous chamber device

By using a combination of semipermeable membrane and normal saline in the arteriovenous pot to isolate air and blood contact, blood retention and coagulation problems are solved, and the risk of thrombosis is reduced and the safety of dialysis treatment is ensured.

CN112245692BActive Publication Date: 2025-07-25SHANDONG WEIGAO BLOOD PURIFICATION PRODUCTS CO LTD
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Patent Information

Application Number
CN202011278555.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-11-16
Publication Date
2025-07-25
Estimated Expiration
2040-11-16

AI Technical Summary

Technical Problem

The existing arteriovenous pot device has serious blood retention and coagulation, resulting in thrombosis and affecting the safety of dialysis treatment.

Method used

A semi-isolated arteriovenous pot device is used to isolate the contact between air and blood with semi-permeable membrane and normal saline. The bubbles are precipitated to the saline side and discharged through the semi-permeable membrane, reducing the risk of blood retention and coagulation.

Benefits of technology

Effectively reduce blood retention and coagulation in the arteriovenous pot, reduce the probability of thrombosis, and ensure the safety of dialysis treatment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a semi-isolated arteriovenous pot device, comprising: a bottle body for loading physiological saline, a semi-permeable membrane provided with a cavity for enclosing blood flow, and a bottle cap for closing the bottle body. An exhaust port is provided at the top of the bottle body, and a bottle cap is provided at the bottom of the bottle body. Two through holes are provided at the bottom of the bottle cap, and the through holes are respectively communicated with the blood inlet and the blood outlet of the blood circulation path. The semi-permeable membrane is located inside the bottle body, and the cavity is communicated with the through holes. This device utilizes a semi-permeable membrane and saline with better blood compatibility to effectively separate the contact between air and blood, making the original air-blood contact interface become an air-water-blood contact interface, which can more effectively remove the air in the blood and reduce the probability of thrombosis. Therefore, this device can effectively reduce blood retention and coagulation in the arteriovenous pot.
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Description

Technical Field

[0001] The present invention relates to the technical field of blood purification, and more specifically, to a semi-isolated arteriovenous pot device. Background Art

[0002] In the prior art, an arterial pot and a venous pot can be used to collect and separate air 01 during blood 02 dialysis. The sources of air 01 mainly include the following three places. One is the residual air 01 in the circulation pipeline. The second is the air 01 infiltrated when the joint seal treatment is not good. The third is the gas released from the blood 02. If these gases enter the human body directly without treatment, different clinical manifestations will occur according to the different contents of air 01 in the blood vessels. If the amount of air 01 entering the blood vessels is small, the bubbles will quickly dissolve in the blood 02 and be quickly metabolized and excreted from the body through the blood 02, and thus will not have a serious impact on the human body. However, if more air 01 enters the blood vessels and the air 01 cannot be completely dissolved in the blood 02 in a short time, air emboli will be formed. As the blood 02 flows, the air emboli will flow to the whole body of the human body. If the air emboli block the lungs, it may cause acute pulmonary infarction, resulting in symptoms of dyspnea in the patient and even sudden death; if the air emboli block the heart, it may cause acute myocardial infarction and endanger the life of the patient; if the air emboli enter the skull, it may cause serious complications such as acute cerebral infarction.

[0003] In order to prevent these gases from entering the human body, a bubble collection bottle (arteriovenous pot) is usually used for bubble collection. Most common arteriovenous pots adopt the form of liquid entering from the upper part and flowing out from the lower part, and the structure is as Figure 1 shown. That is, an exhaust port 4 and a first through hole for inputting blood are provided at the top of the bottle body 1, and a second through hole for outputting blood is provided at the bottom of the bottle body 1. Among them, the first through hole is communicated with the blood inlet 5 of the circulation blood path, and the second through hole is communicated with the blood outlet 6 of the circulation blood path. Therefore, when the blood 02 containing gas enters the bottle body 1, the blood 02 can be temporarily stored in the bottle. During this process, the bubbles will float up, and then the blood 02 is discharged from the bottom of the bottle body 1, so as to achieve the effect of removing bubbles.

[0004] However, due to the structure of the bottle body 1, the blood 02 in the upper part of the bottle body 1 cannot return to the human body in time. At the same time, due to reasons such as temperature difference, water evaporation, and long-term contact oxidation with air 01, an annular thrombus will be formed on the contact surface of the air 01 and blood 02 in the arteriovenous pot, and the annular thrombus will gradually grow. If the patient belongs to an easily coagulable system, the thrombus will grow more rapidly, which may block the filter screen or the dialyzer, resulting in the inability to carry out dialysis treatment normally and ultimately affecting the treatment safety of the patient.

[0005] In summary, how to reduce blood stasis and coagulation in the arteriovenous chamber is an urgent problem to be solved by those skilled in the art at present. Summary of the Invention

[0006] In view of this, the purpose of the present invention is to provide a semi-isolated arteriovenous chamber device, which can effectively reduce blood stasis and coagulation in the arteriovenous chamber, effectively remove air in the blood, and reduce the probability of thrombus formation.

[0007] In order to achieve the above purpose, the present invention provides the following technical solutions:

[0008] A semi-isolated arteriovenous chamber device, comprising: a bottle body for loading physiological saline, a semi-permeable membrane forming a cavity for blood flow, and a bottle cap for closing the bottle body. An exhaust port is provided at the top of the bottle body, and the bottle cap is provided at the bottom of the bottle body. Two through holes are provided at the bottom of the bottle cap, and the through holes are respectively communicated with the blood inlet and the blood outlet of the blood circulation path. The semi-permeable membrane is located inside the bottle body, and the cavity is communicated with the through holes.

[0009] Preferably, the internal pressure of the bottle body is negative pressure.

[0010] Preferably, the bottle body is provided with two exhaust ports.

[0011] Preferably, the bottle cap and the bottle body are welded or bonded.

[0012] Preferably, the semi-permeable membrane is a flexible tube, and both ends of the flexible tube are respectively and correspondingly communicated with the two through holes.

[0013] Preferably, the connection between the bottle cap and the flexible tube is a sealed connection.

[0014] Preferably, the cavity is a spherical structure.

[0015] Preferably, the connection between the bottle cap and the spherical structure is a sealed connection.

[0016] When using the semi-isolated arteriovenous chamber device provided by the present invention, first, inject physiological saline into the bottle body through the exhaust port. The physiological saline can moisten the semi-permeable membrane. Then, respectively communicate the two through holes at the bottom of the bottle cap with the blood inlet and the blood outlet, so that blood can enter the through holes from the blood inlet, then enter the cavity, and then the blood can flow along the cavity. During the flow of the blood, as the space of the cavity increases, the blood flow rate slows down and the pressure decreases, so that the bubbles in the blood are precipitated through the semi-permeable membrane, that is, the bubbles pass through the semi-permeable membrane to the side of the physiological saline. Then, the bubbles rise and gather at the top of the bottle body and are discharged from the exhaust port. The blood that has excluded the bubbles will flow from the cavity to the other through hole and finally flow out to the blood outlet, thus effectively realizing the operation of removing air bubbles from the blood and avoiding blood stasis.

[0017] This device uses a semi-permeable membrane and saline with better blood compatibility to effectively separate the contact between air and blood, making the original air-blood contact interface become an air-water-blood contact interface, which can more effectively remove air from the blood and reduce the probability of thrombosis.

[0018] In summary, the semi-isolated arteriovenous chamber device provided by the present invention can effectively reduce blood stasis and coagulation in the arteriovenous chamber, effectively remove air from the blood, and reduce the probability of thrombosis. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only the embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on the provided drawings.

[0020] Figure 1 is a schematic structural diagram of an arteriovenous chamber in the prior art;

[0021] Figure 2 is a schematic structural diagram of the semi-isolated arteriovenous chamber device provided by the present invention.

[0022] Figure 1 - Figure 2 Wherein:

[0023] 01 is air, 02 is blood, 1 is the bottle body, 2 is the semi-permeable membrane, 3 is the bottle cap, 4 is the exhaust port, 5 is the blood inlet, 6 is the blood outlet, 7 is physiological saline, and 8 is the cavity. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0024] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0025] The core of the present invention is to provide a semi-isolated arteriovenous chamber device, which can effectively reduce blood stasis and coagulation in the arteriovenous chamber, effectively remove air from the blood, and reduce the probability of thrombosis.

[0026] Please refer to Figure 2 , Figure 2 is a schematic structural diagram of the semi-isolated arteriovenous chamber device provided by the present invention.

[0027] This specific embodiment provides a semi-isolated arteriovenous pot device, including: a bottle body 1 for loading physiological saline 7, a semi-permeable membrane 2 provided with a cavity 8 surrounding the blood flow, and a bottle cap 3 for closing the bottle body 1. An exhaust port 4 is provided at the top of the bottle body 1, and a bottle cap 3 is provided at the bottom of the bottle body 1. Two through holes are provided at the bottom of the bottle cap 3, and the through holes are respectively communicated with the blood inlet 5 and the blood outlet 6 of the circulatory blood path. The semi-permeable membrane 2 is located inside the bottle body 1, and the cavity 8 is communicated with the through holes.

[0028] It should be noted that the exhaust port 4 at the top of the bottle body 1 is not only used for exhausting air, but also can be used for filling physiological saline 7. The exhaust port 4 can be connected to a section of catheter, and then the rear end of the catheter is connected to an exhaust device to perform the device exhaust operation, which can improve the exhaust efficiency, and can also perform automatic exhaust through the exhaust port 4.

[0029] It should also be noted that the semi-permeable membrane 2 is a membrane material with very small pores. By selecting a membrane material with a suitable pore size, the separation of air bubbles and blood can be effectively achieved, ensuring that the blood in the cavity 8 will not flow to the side of the physiological saline 7. The two through holes on the bottle cap 3 are mainly used to connect the circulatory blood path to realize the inflow and outflow of blood in the cavity 8.

[0030] In addition, it should be noted that since the semi-permeable membrane 2 is a soft material part, the semi-permeable membrane 2 is arranged on the bottle cap 3, which can effectively support and fix the semi-permeable membrane 2, facilitate the installation of the semi-permeable membrane 2 into the bottle body 1 for related operations, and also facilitate the manufacturing and processing of the device.

[0031] In the actual application process, the shapes, structures, sizes, materials, etc. of the bottle body 1, the semi-permeable membrane 2, and the bottle cap 3 can be determined according to the actual situation and actual needs.

[0032] When using the semi-isolated arteriovenous pot device provided by the present invention, first, physiological saline 7 is injected into the bottle body 1 through the exhaust port 4. The physiological saline 7 can moisten the semi-permeable membrane 2. Then, the two through holes at the bottom of the bottle cap 3 are respectively communicated with the blood inlet 5 and the blood outlet 6, so that blood can enter the through holes from the blood inlet 5 and then enter the cavity 8. Then the blood can flow along the cavity 8. As the space of the cavity 8 increases during the blood flow, the blood flow rate slows down and the pressure decreases, so that the air bubbles in the blood precipitate through the semi-permeable membrane 2, that is, the air bubbles pass through the semi-permeable membrane 2 to reach the side of the physiological saline 7. Then, the air bubbles rise and gather at the top of the bottle body 1 and are discharged from the exhaust port 4. The blood from which the air bubbles have been removed will flow from the cavity 8 to the other through hole and finally flow out to the blood outlet 6, thus effectively realizing the operation of removing air bubbles from the blood and avoiding the phenomenon of blood retention.

[0033] This device utilizes a semi-permeable membrane 2 with better blood compatibility and saline to effectively separate the contact between air and blood, changing the original air-blood contact interface to an air-water-blood contact interface, which can more effectively remove air from the blood and reduce the probability of thrombosis.

[0034] In summary, the semi-isolated arteriovenous flask device provided by the present invention can effectively reduce blood stasis and coagulation phenomena in the arteriovenous flask, effectively remove air from the blood, and reduce the probability of thrombosis.

[0035] On the basis of the above embodiments, preferably, the internal pressure of the bottle body 1 is negative pressure.

[0036] It should be noted that the internal pressure of the bottle body 1 being negative pressure can be achieved by injecting negative-pressure saline into the bottle body 1 to make the internal pressure of the bottle body 1 in a negative-pressure state. During the process of bubbles precipitating from the semi-permeable membrane 2, due to the negative-pressure state on the side of the physiological saline 7, it will be more conducive to the precipitation of bubbles and improve the exhaust effect. When the bubbles are discharged and enter the side of the physiological saline 7, they can be discharged from the bottle body 1 together with the physiological saline 7, thereby effectively separating the bubbles and the blood.

[0037] Preferably, the bottle body 1 is provided with two exhaust ports 4. Setting two exhaust ports 4 on the bottle body 1 facilitates the circulation operation of the negative-pressure saline, is conducive to improving the precipitation efficiency of bubbles, and accelerating the separation process of bubbles and blood.

[0038] Preferably, the bottle cap 3 and the bottle body 1 are welded or bonded to ensure a tight connection between the bottle cap 3 and the bottle body 1, so that the bottle cap 3 will not be washed open after the physiological saline 7 is injected into the bottle body 1, ensuring the stability of the device structure, guaranteeing that the physiological saline 7 will not leak, and providing a stable environment for the operation of removing air from the blood.

[0039] On the basis of the above embodiments, preferably, the semi-permeable membrane 2 is a hose, and both ends of the hose are respectively in corresponding communication with two through holes.

[0040] It should be noted that the physiological saline 7 is injected into the bottle body 1 through the exhaust port 4, and then the semi-permeable membrane 2 is wetted. Then, the two through holes at the bottom of the bottle cap 3 are respectively in communication with the blood inlet 5 and the blood outlet 6, so that blood can enter the through hole from the blood inlet 5, then enter the inlet of the hose, and then the blood can flow along the hose. During the flow process of the blood, as the pipe diameter becomes larger, the blood flow rate slows down and the pressure becomes smaller, causing the bubbles in the blood to precipitate. The bubbles pass through the semi-permeable membrane 2 to reach the side of the physiological saline 7, and then the bubbles rise and gather at the top of the bottle body 1 and are discharged from the exhaust port 4, or the bubbles are pumped out by a pumping device through the exhaust port 4. The blood from which the bubbles have been removed continues to flow, flows to the outlet of the hose, then flows to another through hole, and finally flows to the blood outlet 6, thereby effectively realizing the operation of removing bubbles from the blood and avoiding blood stasis phenomena.

[0041] Preferably, the bottle cap 3 is hermetically connected to the flexible tube.

[0042] It should be noted that the two through holes of the bottle cap 3 are respectively communicated with the two ends of the flexible tube, and a hermetic connection is provided between the outer peripheral portion of the end of the flexible tube and the inner peripheral portion of the through hole of the bottle cap 3, so as to effectively prevent blood from leaking to the side of the physiological saline 7.

[0043] On the basis of the above embodiments, preferably, the cavity 8 is a spherical structure, and the two through holes are located inside the spherical structure, and the spherical structure can be set as an ellipsoid or a spherical structure, etc.

[0044] It should be noted that the cavity 8 being a spherical structure means that the semi-permeable membrane 2 is set as a structure similar to a balloon, and the two through holes are arranged at the air inlet of the balloon. Moreover, a connecting tube can be arranged at the through hole of the bottle cap 3, and the connecting tube extends into the cavity 8 to ensure that blood can flow into the semi-permeable membrane 2 and the blood with bubbles separated can flow out of the semi-permeable membrane 2, so as to realize the blood flow circulation and avoid the phenomenon of blood stasis. The spherical structure surrounded by the semi-permeable membrane 2 can provide a space for the blood, so that the bubbles in the blood are released. When the bubbles pass through the semi-permeable membrane 2 and reach the side of the physiological saline 7, the bubbles can be pumped away together with the negative-pressure saline, or the bubbles can automatically rise to the exhaust port 4 and then be discharged outwards. And, since the working principle of setting the semi-permeable membrane 2 as a spherical structure is similar to the working principle of setting the semi-permeable membrane 2 as a flexible tube, it will not be elaborated here.

[0045] Preferably, a hermetic connection is provided between the bottle cap 3 and the spherical structure to effectively prevent blood from leaking to the side of the physiological saline 7.

[0046] In the actual application process, the shape, structure, size, material, etc. of the flexible tube and the spherical structure can be determined according to the actual situation and actual needs.

[0047] It should also be noted that the semi-isolated arteriovenous pot device provided by the present invention uses the semi-permeable membrane 2 to separate blood bubbles. And, this device effectively isolates air from blood by using the physiological saline 7, and also sets the internal pressure of the bottle body 1 as negative pressure, which is beneficial to accelerating the separation of air in the blood, reducing the contact time between blood and air, and thus reducing the possibility of blood drying and coagulation.

[0048] In addition, the semi-permeable membrane 2 of this device is provided with a cavity 8 that facilitates blood flow. The cavity 8 can effectively improve the blood flow direction in the arteriovenous pot, reduce blood stasis and coagulation phenomena, that is, effectively reduce the blood chamber volume, so that this device can realize the bubble separation operation with less volume of blood. And, in special cases, the operator can change the pressure, temperature, components, etc. of the physiological saline 7 to form a better degassing environment, so as to better pre-treat the blood and facilitate a more stable dialysis treatment.

[0049] In addition, it should be noted that the orientation or positional relationship indicated by "top and bottom", "inside and outside", etc. in this application is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of simplifying the description and understanding, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present invention.

[0050] The various embodiments in this specification are described in a progressive manner. Each embodiment focuses on the differences from other embodiments. For the same or similar parts among the various embodiments, reference can be made to each other. Any combination of all the embodiments provided by the present invention falls within the protection scope of this invention, and will not be elaborated here.

[0051] The semi-isolated arteriovenous pot device provided by the present invention has been introduced in detail above. Specific examples are used herein to elaborate on the principle and implementation manner of the present invention. The description of the above embodiments is only for helping to understand the method and its core idea of the present invention. It should be noted that for those of ordinary skill in the art in this technical field, without departing from the principle of the present invention, several improvements and modifications can still be made to the present invention, and these improvements and modifications also fall within the protection scope of the claims of the present invention.

Claims

1. A semi-isolated arteriovenous pot device, characterized in that Comprising: A bottle body (1) for loading physiological saline (7), a semi-permeable membrane (2) provided with a cavity (8) surrounding blood flow, and a bottle cap (3) for closing the bottle body (1). An exhaust port (4) is provided at the top of the bottle body (1), the bottle cap (3) is provided at the bottom of the bottle body (1), two through holes are provided at the bottom of the bottle cap (3), the through holes are respectively communicated with a blood inlet (5) and a blood outlet (6) of a circulating blood path, the semi-permeable membrane (2) is located inside the bottle body (1), and the cavity (8) is communicated with the through holes; The bottle body (1) is provided with two of the exhaust ports (4); The bottle cap (3) and the bottle body (1) are welded or bonded; The semi-permeable membrane (2) is a flexible tube, and two ends of the flexible tube are respectively and correspondingly communicated with the two through holes.

2. The semi-isolated arteriovenous pot device according to claim 1, wherein A sealed connection is provided between the bottle cap (3) and the flexible tube.

3. A semi-isolated arteriovenous pot device, characterized in that, Comprising: A bottle body (1) for loading physiological saline (7), a semi-permeable membrane (2) provided with a cavity (8) surrounding blood flow, and a bottle cap (3) for closing the bottle body (1). An exhaust port (4) is provided at the top of the bottle body (1), the bottle cap (3) is provided at the bottom of the bottle body (1), two through holes are provided at the bottom of the bottle cap (3), the through holes are respectively communicated with a blood inlet (5) and a blood outlet (6) of a circulating blood path, the semi-permeable membrane (2) is located inside the bottle body (1), and the cavity (8) is communicated with the through holes; The bottle body (1) is provided with two of the exhaust ports (4); The bottle cap (3) and the bottle body (1) are welded or bonded; The cavity (8) is of a spherical structure.

4. The semi-isolated arteriovenous pot device according to claim 3, characterized in that, A sealed connection is provided between the bottle cap (3) and the spherical structure.

Citation Information

Patent Citations

  • Semi-isolated arteriovenous pot device

    CN213789210U