Sample analyzer and sample addition method
By setting independent sample filling positions and empty cup areas in the sample analyzer and controlling the sample filling action of the sample filling device with the sensor, the problem of mis-adding of the sample filling device is solved, and the sample saving and analysis efficiency are improved.
Patent Information
- Application Number
- CN201911206563.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2019-11-29
- Publication Date
- 2025-07-11
- Estimated Expiration
- 2039-11-29
AI Technical Summary
In existing sample analyzers, sample feeders often add samples to non-target reaction cups or places where there is no reaction cup, resulting in waste of samples and inefficient analysis.
A sample loading assembly is designed, including a workbench, a sample filler and a cup holder. By setting up independent sample loading positions and empty cup areas on the workbench, the sensor is used to sense whether the cup holder clamps the reaction cup to ensure that each sample loading action of the sample loader is carried out in a fixed position to avoid misapplying samples.
It effectively avoids the sample loader adding samples to non-target reaction cups or places where there is no reaction cup placed, saves samples, improves analysis efficiency, and optimizes the working efficiency of the sample loading assembly and sample analyzer.
Smart Images

Figure CN112881740B_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of medical devices, and more specifically, relates to a sample analyzer and a sample adding method. Background Art
[0002] In the field of biomedicine, sample analysis often requires adding a certain amount of sample and reagent into a reaction cup, and observing the reaction process of the reagent and the sample or analyzing the reaction product of the reagent and the sample to obtain the analysis result of the sample. In existing sample analyzers, a sampler is mostly used to add samples into the reaction cups on the cup tray. However, due to the poor design rationality of the sample adding component in the sample analyzer, the sampler often adds samples into non-target reaction cups or positions without reaction cups, which not only causes waste of samples but also affects the analysis efficiency. Summary of the Invention
[0003] An object of the present invention is to provide a sample adding component to solve the technical problem that existing sample analyzers often add samples into non-target reaction cups or positions without reaction cups.
[0004] To achieve the above object, the technical solution adopted by the present invention is: providing a sample adding component, including:
[0005] A workbench, provided with an empty cup area for placing reaction cups and a sample adding position for fixing sample addition;
[0006] A sampler, used to move relative to the workbench to add samples into the reaction cup located at the sample adding position; and
[0007] A first cup gripper, used to move relative to the workbench to transfer the reaction cup from the empty cup area to the sample adding position and to move the reaction cup out of the sample adding position.
[0008] Further, the sample adding position is independent of the empty cup area.
[0009] Further, the sample adding component further includes a sensor for sensing whether the first cup gripper has clamped the reaction cup, and the sensor is arranged on the first cup gripper.
[0010] The present invention also provides a sample analyzer, which includes a second cup gripper and the above-mentioned sample adding component;
[0011] The workbench is further provided with a transfer area, an incubation area and a detection area. The first cup gripper is used to transfer the reaction cup from the sample adding position to the incubation area and to transfer the reaction cup from the incubation area to the transfer area. The second cup gripper is used to move relative to the workbench to transfer the reaction cup from the transfer area to the detection area.
[0012] The present invention also provides a sample adding method, including the following steps:
[0013] Control the first cup gripper to transfer the reaction cup from the empty cup area to the sample adding position;
[0014] Control the sampler to add a sample into the reaction cup at the sample adding position;
[0015] Control the first cup gripper to transfer the reaction cup with the added sample from the sample adding position to the incubation area.
[0016] Further, the step of controlling the first cup gripper to transfer the reaction cup from the empty cup area to the sample adding position includes the following steps:
[0017] Control the first cup gripper to pick up the reaction cup;
[0018] Transfer the picked-up reaction cup to the sample adding position.
[0019] Further, after the step of controlling the first cup gripper to pick up the reaction cup, the following steps are included:
[0020] The sensor senses whether the first cup gripper has picked up the reaction cup;
[0021] When the sensor senses that the first cup gripper has picked up the reaction cup, control the first cup gripper to transfer the picked-up reaction cup to the sample adding position;
[0022] When the sensor senses that the first cup gripper has not picked up the reaction cup, control the first cup gripper to move a preset distance and then control the first cup gripper to pick up the reaction cup again.
[0023] Further, the empty cup area is provided with a plurality of placement positions, each placement position is used to place one reaction cup, and the distance between two adjacent placement positions is the preset distance.
[0024] Further, before the step of controlling the first cup gripper to transfer the reaction cup from the empty cup area to the sample adding position, the following steps are also included:
[0025] Control the sampler to move to the sample area and aspirate the sample.
[0026] Further, after the step of controlling the first cup gripper to transfer the reaction cup from the sample adding position to the incubation area, the following steps are also included:
[0027] Control the first cup gripper to transfer the reaction cup from the incubation area to the transfer area.
[0028] Further, after the step of controlling the first cup gripper to transfer the reaction cup from the incubation area to the transfer area, the following steps are included:
[0029] Control the second cup gripper to grip the reaction cup in the transfer area;
[0030] Control the second cup gripper to transfer the reaction cup into the air to make the reaction cup in a suspended state;
[0031] Control the reagent needle to add reagent into the reaction cup held by the second cup gripper;
[0032] Control the second gripper to transfer the reaction cup to the detection area.
[0033] The beneficial effects of the sample analyzer and the sample addition method provided by the present invention are as follows: Since the sample addition position is a fixed position for sample addition, that is, each sample addition action of the sampler is performed at a fixed position, and the sampler adds samples to the reaction cup immediately located at the sample addition position, without the need to adjust the sample addition position according to the different positions of each reaction cup, effectively avoiding the possibility that the sampler adds samples to non-target reaction cups or positions without reaction cups placed, which helps to save samples and improve the analysis efficiency. Description of the Drawings
[0034] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.
[0035] Figure 1 Structural schematic diagram of a sample analyzer provided by an embodiment of the present invention;
[0036] Figure 2 For Figure 1 Enlarged structural schematic diagram of part A in
[0037] Figure 3 Flow schematic diagram of a sample addition method provided by an embodiment of the present invention;
[0038] Figure 4 Flow schematic diagram of a sample addition method provided by an embodiment of the present invention;
[0039] Figure 5 Flow schematic diagram of step S100 in an embodiment of the present invention.
[0040] Figure 6 Flow schematic diagram of a sample addition method provided by another embodiment of the present invention;
[0041] Figure 7 A flowchart diagram of the sample addition method provided for another embodiment of the present invention.
[0042] Among them, the reference numerals in the figure are as follows:
[0043] 10. Sample analyzer; 11. Sampling assembly; 100. Workbench; 110. Incubation area; 120. Sampling position; 121. First sampling position; 122. Second sampling position; 130. Sample area; 140. Transfer area; 150. Reagent area; 160. Detection area; 170. Empty cup area; 200. Sampler; 300. First cup gripper; 400. Reagent needle; 20. Reaction cup; 21. Square-mouth cup; 22. Round-mouth cup; 30. Cup tray; 40. Turntable; 50. Channel. Detailed implementation manners
[0044] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.
[0045] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.
[0046] It should be understood that the orientation or positional relationship indicated by the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention.
[0047] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality of" means two or more unless otherwise specifically defined.
[0048] Please refer to together Figures 1 to 2, the sample analyzer 10 provided by the present invention will be described hereinafter. The sample analyzer 10 includes a sample adding assembly 11, a second cup gripper (not shown in the figure), and a reagent needle 400. Among them, the sample adding assembly 11 includes a workbench 100, a sampler 200, and a first cup gripper 300. A sample adding position 120 for fixing sample adding, an incubation area 110 for incubating samples, a sample area 130 for storing samples, a reagent area 150 for storing reagents, a detection area 160 for detecting samples, a transfer area 140 for transferring reaction cups 20, and an empty cup area 170 for placing reaction cups 20 are provided on the workbench 100. The transfer area 140 is provided between the incubation area 110 and the detection area 160. It should be noted that in the present invention, the empty cup area 170 refers to the area for placing reaction cups 20 without added samples or reagents, and it cannot be understood as only for placing reaction cups without items. For example, when the sample analyzer uses the magnetic bead method for coagulation project analysis, magnetic beads are placed in the reaction cups 20 placed in the empty cup area 170.
[0049] The sampler 200, the first cup gripper 300, the second cup gripper, and the reagent needle 400 can all move relative to the workbench 100. Specifically, the first cup gripper 300, the second cup gripper, the reagent needle 400, and the sampler 200 can all move in the horizontal direction and the vertical direction relative to the workbench 100, so as to be able to move between the respective areas of the workbench 100, enabling the sampler 200 to complete the actions of sucking and adding samples, enabling the reagent needle 400 to complete the actions of sucking and adding reagents, and enabling the first cup gripper 300 and the second cup gripper to complete the actions of clamping and moving the reaction cup 20.
[0050] In this way, since the sample adding position 120 is a fixed position for sample adding, that is, each sample adding action of the sampler 200 is performed at a fixed position. The sampler 200 adds samples into the reaction cup 20 immediately located at the sample adding position 120, without the need to adjust the sample adding position according to the different positions of each reaction cup 20, effectively avoiding the possibility that the sampler 200 adds samples to non-target reaction cups 20 or positions without reaction cups 20, which helps to save samples and improve the analysis efficiency.
[0051] In addition, the sample adding position 120 is independent of the empty cup area 170. Since the first cup gripper 300 needs to pick up the reaction cup 20 from the empty cup area 170, setting the sample adding position 120 independently outside the empty cup area 170 enables the first cup gripper 300 to go to the empty cup area 170 to continue picking up cups after withdrawing from the sample adding position 120 when the sampler 120 adds samples at the sample adding position 120. In this way, not only the sample adding efficiency of the sample adding assembly 11 is improved, the analysis efficiency of the sample analyzer 10 is improved, but also the movement interference between the sampler 200 and the first cup gripper 300 can be effectively avoided.
[0052] In this embodiment, the sampling component 10 can adopt two methods, namely the magnetic bead method and the optical method, for coagulation project analysis. Among them, the reaction cup used in the magnetic bead method is a square-mouth cup 21, and the reaction cup used in the optical method is a round-mouth cup 22. A cup tray 30 and a turntable 40 are arranged in the empty cup area 170. The cup tray 30 is provided with a plurality of placement positions for placing the square-mouth cups 21; the turntable 40 is provided with a plurality of placement positions for placing the round-mouth cups 22. Specifically, please refer to Figure 1 and Figure 2 , the turntable 40 can rotate relative to the workbench so that each placement position on the turntable 40 can communicate with and face the channel 50 for inputting the round-mouth cups 22. In this way, the round-mouth cups 22 can slide from the channel 50 onto the placement positions of the turntable 40, which can not only reduce the workload of the staff adding the round-mouth cups 22, but also reduce the movement distance of the first cup gripper 300 that comes to pick up the round-mouth cups 22, thereby improving the analysis efficiency.
[0053] Since the external dimensions of the square-mouth cup 21 and the round-mouth cup 22 are different, in this embodiment, there are two sampling positions 120. One is the first sampling position 121 for placing the square-mouth cup 21, and the first sampling position 121 is in the shape of a square hole. The other is the second sampling position 122 for placing the round-mouth cup 22, and the second sampling position 122 is in the shape of a round hole. The sampler 200 can sample the square-mouth cup 21 on the first sampling position 121 and the round-mouth cup 22 on the second sampling position 122.
[0054] Of course, in other embodiments of the present invention, the turntable 40 can be replaced with a cup tray capable of placing the round-mouth cups 22, or the cup tray 30 can be replaced with a turntable capable of placing the square-mouth cups 21, or the cup tray 30 or the turntable 40 can be omitted, and the placement positions can be directly set in the empty cup area 170 of the workbench 100. There is no unique limitation here.
[0055] Taking the magnetic bead method as an example, the specific working process of the sample analyzer 10 provided by the present invention is as follows:
[0056] The first cup gripper 300 moves the reaction cup 20 on the cup tray 30 to the first sampling position 121. The sampler 200 aspirates a sample from the sample area 130 and then injects the aspirated sample into the square-mouth cup 21 at the first sampling position 121. Then, the first cup gripper 300 moves the square-mouth cup 21 with the sample to the incubation area 110. Since incubation takes a certain amount of time, during the incubation of the sample, the first cup gripper 300 returns to the cup tray 30 and continues to repeat the above actions. In this way, the sampling efficiency can be optimized, and thus the analysis efficiency can be further optimized. After the sample in the incubation area is incubated, the first cup gripper 300 transfers the square-mouth cup 21 with the incubated sample to the transfer area 140. Then, the second cup gripper moves the square-mouth cup 21 in the transfer area 140 to the detection area 160. The reagent needle 400 aspirates a reagent in the reagent area 150. During the process of the second cup gripper moving the square-mouth cup 21, the reagent needle 400 injects the aspirated reagent into the square-mouth cup 21 clamped by the second cup gripper.
[0057] Of course, the second cup gripper can also move the square-mouth cup 21 to a stop in the air, and then the reagent needle 400 injects the aspirated reagent into the square-mouth cup 21 clamped by the second cup gripper. The reagent addition time of the above two methods overlaps with the time of the second gripper transferring the square-mouth cup 21, thereby optimizing the analysis efficiency. Of course, in other embodiments of the present invention, the reagent needle 400 can also add a reagent into the square-mouth cup 21 when the square-mouth cup 21 is placed in the transfer area 140 or in the detection area 160.
[0058] Moreover, since the transfer area 140 is provided between the incubation area 110 and the detection area 160, the movement distance of the first cup gripper 300 and the second cup gripper can be effectively reduced, improving the analysis efficiency.
[0059] In addition, the above second gripper and the transfer area 140 can also be omitted. The first gripper 300 directly sends the incubated sample to the detection area 160, and the reagent needle 400 adds a reagent into the square-mouth cup 21 during this process. In this way, the time required for transfer can be saved, and at the same time, the cost of setting up the second gripper can be saved. Specifically, the reagent needle 400 has a heating function, so that the reagent in the aspirated reagent needle 400 can be heated before being added to the square-mouth cup 21. In this way, the time and device for separately heating the reagent can be saved. On the one hand, the structure of the sample analyzer 10 can be simplified, and on the other hand, time is saved, improving the analysis efficiency of the sample analyzer 10.
[0060] In one embodiment, the sample loading assembly 11 further includes a sensor (not shown in the figure). The sensor is disposed on the first cup gripper 300 and is configured to sense whether a square cup 21 is gripped on the first cup gripper 300. When the sensor senses that the square cup 21 is gripped by the first cup gripper 300, the square cup 21 is moved to the first sample loading position 121. When the sensor senses that the first cup gripper 300 does not grip the square cup 21, it will grip again after moving a preset distance. It should be noted that the preset distance here is the distance from one placement position to an adjacent placement position. When the distances between the placement positions on the cup tray are equal, the preset distance is a fixed value. For example, the preset distance is 5 cm, 8 cm, 10 cm, 12 cm, or 15 cm, etc. When the distances between the placement positions on the cup tray are not equal, then the preset distance is a variable and should be determined according to the actual distance between the position where the first cup gripper 300 is located and the adjacent placement position.
[0061] In addition, the sensor can be a contact sensor or a non-contact sensor. The non-contact sensor can be an optical sensor or a vision sensor, etc., and can be selected according to actual needs, and is not uniquely limited here.
[0062] It can be understood that, compared with the magnetic bead method, the difference in the working process of the sample loading assembly 11 when using the optical method for analysis lies in the devices for placing empty cups and the sample loading positions 120. Specifically, the magnetic bead method uses a first sample loading position 121 in the shape of a square hole, while the optical method uses a second sample loading position 122 in the shape of a round hole; the magnetic bead method uses a cup tray 30 to place the square cup 21, and the optical method uses a turntable 40 to place the round cup 22. And since the turntable 40 can drive the round cup 22 to move, when the sensor cannot sense the round cup 22, the turntable 40 rotates to bring the round cup 22 closer to the first cup gripper 300, thereby reducing the moving distance of the first cup gripper 300; the remaining features are the same as those of the magnetic bead method and will not be elaborated here.
[0063] Please refer to Figures 1 to 5 , based on the above sample loading assembly 11, an embodiment of the present invention further provides a sample loading method.
[0064] S100: Control the first cup gripper 300 to transfer the reaction cup 20 from the empty cup area 170 to the sample loading position 120;
[0065] S200: Control the sampler 200 to add a sample into the reaction cup 20 at the sample loading position 120;
[0066] S300: Control the first cup gripper 300 to transfer the reaction cup 20 with the sample added from the sample loading position 120 to the incubation area 110.
[0067] S400: Control the first cup gripper 300 to transfer the reaction cup 20 from the incubation area 110 to the transfer area 140.
[0068] S510: Control the second cup gripper to grip the reaction cup 20 in the transfer area 140;
[0069] S520: Control the second cup gripper to transfer the reaction cup 20 into the air to make the reaction cup 20 in a suspended state;
[0070] S530: Control the reagent needle 400 to add reagents into the reaction cup 20 held by the second cup gripper;
[0071] S540: Control the second gripper to transfer the reaction cup 20 to the detection area 160.
[0072] Among them, S100 includes:
[0073] S110: Control the first cup gripper 300 to pick up the reaction cup 20;
[0074] S120: Transfer the picked-up reaction cup 20 to the sample addition position 120.
[0075] Between steps S110 and S120, it further includes:
[0076] S111: The sensor senses whether the first cup gripper 300 has picked up the reaction cup 20;
[0077] When the sensor senses that the first cup gripper 300 has picked up the reaction cup 20, then control the first cup gripper 300 to transfer the picked-up reaction cup 20 to the sample addition position 120;
[0078] When the sensor senses that the first cup gripper 300 has not picked up the reaction cup 20, then control the first cup gripper 300 to move a preset distance and then control the first cup gripper 300 to pick up the reaction cup 20 again.
[0079] Before step S200, it further includes:
[0080] S210: Control the sampler 200 to move to the sample area 130 and aspirate the sample.
[0081] The above sample addition method can be applied to the analysis of coagulation items by the magnetic bead method or the optical method. Please refer to Figures 1 to 5 , now taking the magnetic bead method as an example, the above sample addition method is elaborated in detail, including the following steps:
[0082] S100: Control the first cup gripper 300 to move the square-mouth cup 21 from the empty cup area 170 to the first sample addition position 121; Specifically, this step S100 includes sub-steps: S110: Control the first cup gripper 300 to pick up the square-mouth cup 21; S120: Move the picked-up square-mouth cup 21 to the first sample addition position 121.
[0083] Between steps S110 and S120, step S111 is further included: the sensor senses whether the first cup gripper 300 holds the square cup 21. When it is sensed that the first cup gripper 300 holds the square cup 21, step S120 is implemented; when it is sensed that the first cup gripper 300 does not hold the square cup 21, step S112 is implemented and then step S110 is implemented again. Step S112 is: controlling the first cup gripper 300 to move a preset distance. Of course, after implementing step S110, if it is sensed that the square cup 21 still cannot be held, S111 is continuously implemented. In this way, the cycle continues until the sensor detects that the first cup gripper 300 holds the square cup 21 and then step S120 is executed. In other embodiments of the present invention, this step S111 can also be omitted, and it can be determined manually whether the first cup gripper 300 holds the square cup 21. There is no unique limitation here.
[0084] In addition, when the sensor continuously senses multiple times that the first cup gripper 300 does not hold the square cup 21, an alarm can be given by means of sound, light, etc. to remind the user to replenish the empty cups so as not to delay the sample addition time and the analysis time.
[0085] After implementing step S120, step S200 is implemented: controlling the sampler 200 to add a sample into the square cup 21 at the first sampling position 121. In step S200, the sampler 200 moves in the vertical direction relative to the workbench 100 to approach or move away from the square cup 21 at the first sampling position 121.
[0086] Before implementing step S200, step S210 is implemented: the sampler 200 moves to the sample area 130 and aspirates the sample. It can be understood that while implementing step S210, the first cup gripper 300 can place the empty square cup 21 at the first sampling position 121. In this way, on the one hand, it can avoid movement interference between the sampler 200 and the first cup gripper 300, and on the other hand, it allows the sampler 200 to perform other tasks during the process of the first cup gripper 300 gripping and moving the square cup 21, thus preparing for sample addition and effectively improving the working efficiency of the entire sample analyzer 10.
[0087] After step S200, step S300 is implemented: controlling the first cup gripper 300 to move the square cup 21 with the added sample to the incubation area 110, thereby starting to incubate the sample.
[0088] In this embodiment, after implementing step S300, step S400 is further implemented: controlling the first cup gripper 300 to move to the incubation area 110 and move the square cup 21 with the incubated sample to the above-mentioned transfer area 140.
[0089] In another embodiment, please refer to Figure 1 、Figure 2 and Figure 6 After implementing step S120, while implementing step S200, step S400 can be implemented: controlling the first cup gripper 300 to move to the incubation area 110, and moving the square-mouth cup 21 with the incubated sample at the incubation area 110 to the above-mentioned transfer area 140. In this way, on the one hand, it can avoid the movement interference between the first cup gripper 300 and the sampler 200, and on the other hand, it allows the first cup gripper 300 to perform other tasks during the sampling and movement of the sampler 200, thereby indirectly improving the working efficiency of the entire sampling assembly 10.
[0090] In another embodiment, please refer to Figure 1 、 Figure 2 and Figure 7 After implementing step S400, implement step S510: controlling the second cup gripper to grip the square-mouth cup 21 at the transfer area 140; S520: controlling the second cup gripper to transfer the square-mouth cup 21 into the air so that the square-mouth cup 21 is in a suspended state; S530: controlling the reagent needle 400 to add reagent into the square-mouth cup 21 held by the second cup gripper; S540: controlling the second cup gripper to transfer the square-mouth cup 21 to the detection area 160. In this way, the time for adding reagent overlaps with the time for the second gripper to transfer the square-mouth cup 21, thereby further improving the analysis efficiency.
[0091] Based on the fact that the first sampling position 121 in the sampling assembly 11 is fixed for sampling, the sampling method provided by the embodiment of the present invention has no risk of sampling to a non-target square-mouth cup 21 or a position without a square-mouth cup 21, and also avoids the risk of movement interference between the sampler 200 and the first cup gripper 300 in each step. Based on the fact that the transfer area 140 in the sample analyzer 10 is provided between the incubation area 110 and the detection area 160, in the sampling method, the movement distances of the first cup gripper 300 and the second cup gripper in each step are shortened, thereby further saving the analysis time and improving the analysis efficiency.
[0092] When this sampling method is applied to the analysis of the coagulation project by the optical method, the step S112: controlling the first cup gripper 300 by a preset distance is replaced by the step of controlling the turntable 40 to rotate by a preset angle, and this preset angle is the central angle between two adjacent placement positions on the turntable 40; the first sampling position 121 is replaced by the second sampling position 122; the cup tray 30 is replaced by the turntable 40; the square-mouth cup 21 is replaced by the round-mouth cup 22. The remaining steps are the same as those for the analysis of the coagulation project by the magnetic bead method and will not be elaborated here.
[0093] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims
1. A sample analyzer, comprising a sample adding assembly and a second cup clamping device, characterized in that, The sample adding assembly includes: A workbench, which is provided with an empty cup area for placing reaction cups and a sample adding position fixed for sample adding; A sampler, which is used to move relative to the workbench to add samples into the reaction cups located at the sample adding position; and A first cup gripper, which is used to move relative to the workbench to transfer the reaction cups from the empty cup area to the sample adding position and can move the reaction cups out of the sample adding position; The sample adding assembly uses two methods, namely the magnetic bead method and the optical method, for coagulation item analysis. The sample adding position includes a first sample adding position and a second sample adding position. The sampler can add samples to the reaction cups at the first sample adding position and the second sample adding position, and magnetic beads are placed in the reaction cups at the first sample adding position; A transfer area, an incubation area and a detection area are further provided on the workbench. The first cup gripper is used to transfer the reaction cups from the sample adding position to the incubation area and transfer the reaction cups from the incubation area to the transfer area. The second cup gripper is used to move relative to the workbench to transfer the reaction cups from the transfer area to the detection area.
2. The sample analyzer according to claim 1, wherein: The sample adding position is independent of the empty cup area.
3. The sample analyzer according to claim 1, wherein: The sample adding assembly further includes a sensor for sensing whether the first cup gripper has clamped the reaction cup, and the sensor is arranged on the first cup gripper.
4. A sample addition method for a sample analyzer according to any one of claims 1-3, characterized in that, It includes the following steps: Controlling the first cup gripper to transfer the reaction cup from the empty cup area to the sample adding position; the sample adding assembly uses two methods, namely the magnetic bead method and the optical method, for coagulation item analysis. The sample adding position includes a first sample adding position and a second sample adding position; Controlling the sampler to add samples into the reaction cups at the sample adding position; the sampler can add samples to the reaction cups at the first sample adding position and the second sample adding position, and magnetic beads are placed in the reaction cups at the first sample adding position; Controlling the first cup gripper to transfer the reaction cups with added samples from the sample adding position to the incubation area; Controlling the first cup gripper to transfer the reaction cups from the incubation area to the transfer area; Controlling the second cup gripper to clamp the reaction cups at the transfer area; Controlling the second cup gripper to transfer the reaction cups into the air so that the reaction cups are in a suspended state; Controlling the reagent needle to add reagents into the reaction cups clamped by the second cup gripper; Controlling the second cup gripper to transfer the reaction cups to the detection area.
5. The sample addition method according to claim 4, wherein: The step of controlling the first cup gripper to transfer the reaction cup from the empty cup area to the sample adding position includes the following steps: Controlling the first cup gripper to clamp the reaction cup; Transferring the clamped reaction cup to the sample adding position.
6. The sample addition method according to claim 5, characterized in that: After the step of controlling the first cup gripper to clamp the reaction cup, the following steps are included: The sensor senses whether the first cup gripper has clamped the reaction cup; When the sensor senses that the first cup gripper has clamped the reaction cup, controlling the first cup gripper to transfer the clamped reaction cup to the sample adding position; When the sensor senses that the first cup gripper has not clamped the reaction cup, controlling the first cup gripper to move a preset distance and then controlling the first cup gripper to clamp the reaction cup again.
7. The sample addition method according to claim 6, characterized in that: The empty cup area is provided with a plurality of placement positions, each of which is used to place one of the reaction cups, and the distance between two adjacent placement positions is the preset distance.
8. The sample addition method according to any one of claims 4 to 7, characterized in that: Before the step of controlling the first cup gripper to transfer the reaction cup from the empty cup area to the sample addition position, the following steps are further included: Control the sampler to move to the sample area and aspirate the sample.
Citation Information
Patent Citations
Reaction cup catching device and sample analyzer
CN105785060A
Single-sample chemical analysis device and sample analysis method thereof
CN110412302A
A blood analysis meter
CN207798860U