Sample mixing method, sample analyzer and readable storage medium

Abstract

The present invention proposes a sample mixing method, comprising: placing a sample container loaded with a sample into a fixed seat of a sample mixing device; first controlling a driving portion of the sample mixing device to drive the fixed seat to rotate at a first rotational speed for a first preset time period, thereby driving the sample container contained in the fixed seat to rotate; and then controlling the driving portion to drive the fixed seat to rotate at a second rotational speed different from the first rotational speed for a second preset time period, thereby driving the sample container contained in the fixed seat to rotate. By changing the rotational speed of the sample container during the vortex mixing process, the plasma loss caused by the sample container always rotating at a higher uniform speed to mix the sample is reduced. The present invention also relates to a sample analyzer using this method and a computer-readable storage medium for implementing this method.

Description

Technical Field

[0001] The present invention relates to the field of blood analysis, and in particular to a sample mixing method, a sample analyzer using the method, and a computer-readable storage medium for implementing the method. Background Art

[0002] In routine blood tests, when collecting blood as a test sample, in order to prevent blood coagulation, a blood collection tube containing an anticoagulant is usually used. Blood is composed of blood cells and plasma. Due to the different specific gravities of blood cells and plasma, the anticoagulated blood will form layers after standing for a period of time (see Figure 1 ), so the blood sample must be fully mixed before testing, otherwise the test results will have a large deviation.

[0003] Currently, commonly used blood sample mixing methods include vortex mixing using a vortex mixer, which creates a vortex by spinning the blood sample. This mixing method is particularly suitable for sample volumes ≤200uL, especially those ≤100uL. However, for smaller sample containers and smaller sample volumes, a vortex mixer typically requires higher speeds to achieve optimal mixing.

[0004] However, since blood samples separate into layers after standing, with blood cells in the lower layer and plasma in the upper layer, if the vortex mixer is constantly rotating at a high speed, there is a risk that some tiny plasma particles from the upper layer will splash onto the inner wall of the sample container and, due to molecular attraction, will not be able to slide back to the bottom of the container. This loss of plasma can lead to an over-representation of blood cells in the blood sample, thus causing deviations in test results. Summary of the Invention

[0005] The present invention provides a variable-speed sample mixing method, a sample analyzer, and a computer-readable storage medium to reduce plasma loss that may be caused by uniform mixing at a higher speed, thereby reducing the probability and amplitude of deviation in sample test results caused by mixing.

[0006] A first aspect of the present invention relates to a sample mixing method, comprising the following steps:

[0007] placing a sample container loaded with the sample into a fixing seat of the sample mixing device;

[0008] First, controlling the driving portion of the sample mixing device to drive the fixing base to rotate at a first rotational speed for a first preset time period, thereby driving the sample container accommodated in the fixing base to rotate;

[0009] The driving unit is then controlled to drive the fixing base to rotate at a second rotation speed different from the first rotation speed for a second preset time period, so as to drive the sample container accommodated in the fixing base to rotate.

[0010] A second aspect of the present invention relates to a sample mixing method, comprising the following steps:

[0011] placing a sample container loaded with the sample into a fixing seat of the sample mixing device;

[0012] The driving unit of the sample mixing device is controlled to drive the fixing base to move in a manner that its driving speed gradually increases from an initial speed to a preset maximum speed, so as to drive the sample container contained in the fixing base to move, thereby mixing the sample in the sample container.

[0013] A third aspect of the present invention relates to a sample analyzer, comprising:

[0014] A sample transport device, used for transporting a sample container loaded with a sample to a mixing position;

[0015] The first mixing device includes a driving portion having a driving shaft and a fixing base fixedly connected to the driving shaft, wherein the driving portion is used to drive the fixing base to rotate via the driving shaft, and the fixing base is used to accommodate a sample container loaded with a sample;

[0016] A transport device, used for transporting the sample container to a fixing seat of the first mixing device;

[0017] A control device is electrically connected to the sample transport device, the drive unit, and the transport device, and is configured to:

[0018] Controlling the transport device to transport the sample container transported to the mixing position to the fixing seat of the first mixing device;

[0019] First, the driving unit is controlled to drive the fixing base to rotate at a first rotation speed for a first preset time period, so as to drive the sample container accommodated in the fixing base to rotate;

[0020] The driving unit is then controlled to drive the fixing base to rotate at a second rotation speed different from the first rotation speed for a second preset time period, so as to drive the sample container accommodated in the fixing base to rotate.

[0021] A fourth aspect of the present invention relates to a sample analyzer, comprising:

[0022] A sample transport device, used for transporting a sample container loaded with a sample to a mixing position;

[0023] The sample mixing device comprises a driving portion having a driving shaft and a fixing base fixedly connected to the driving shaft, wherein the driving portion is used to drive the fixing base to rotate via the driving shaft, and the fixing base is used to accommodate a sample container loaded with a sample;

[0024] A transport device, used for transporting the sample container to a fixing seat of the first mixing device;

[0025] A control device is electrically connected to the sample transport device, the drive unit, and the transport device, and is configured to:

[0026] Controlling the transport device to transport the sample container transported to the mixing position to the fixing seat of the first mixing device;

[0027] The driving unit is controlled to drive the fixing base to move in a manner that its driving speed gradually increases from an initial speed to a preset maximum speed, so as to drive the sample container contained in the fixing base to move, thereby performing a mixing operation on the sample in the sample container.

[0028] Finally, a fifth aspect of the present invention also relates to a computer-readable storage medium storing executable instructions, configured to cause a processor to execute the executable instructions to implement the above-mentioned sample mixing method.

[0029] According to the present invention, after a sample container containing a sample is placed in the holder of the first mixing device, the sample container contained in the holder is rotated by controlling the driving unit of the first mixing device to drive the holder to rotate at a first rotational speed for a first preset time period and then at a second rotational speed different from the first rotational speed for a second preset time period. Throughout the mixing process, the sample container's rotational speed is varied to achieve variable-speed vortex mixing of the blood sample, thereby reducing plasma loss caused by uniform mixing at a higher speed, and thereby lowering the risk of inaccurate test results. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 is a schematic diagram of the blood sample involved in the present invention being layered in an anticoagulation sample container;

[0031] Figure 2 is a schematic diagram of a sample analyzer of the present invention;

[0032] Figure 3 is a schematic diagram of the internal structure of the sample analyzer of the present invention;

[0033] Figure 4 is a schematic diagram of the internal structure of the sample analyzer of the present invention;

[0034] Figure 5 is a schematic diagram of a sample transport device of a sample analyzer according to the present invention;

[0035] Figure 6 is a schematic diagram of a first mixing device of a sample analyzer of the present invention;

[0036] Figure 7 It is a partial schematic diagram of the first mixing device of the sample analyzer of the present invention;

[0037] Figure 8 is a schematic diagram of pulses output by the sensor of the sample analyzer of the present invention;

[0038] Figure 9 is a cross-sectional schematic diagram of another embodiment of the first mixing device of the sample analyzer of the present invention;

[0039] Figures 10 to 19 is a schematic flow chart of different embodiments of the sample mixing method of the present invention;

[0040] Figure 20 is a schematic diagram of a computer-readable storage medium of the present invention. DETAILED DESCRIPTION

[0041] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts shall fall within the scope of protection of the present invention.

[0042] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in the present invention include direct and indirect connections (couplings) unless otherwise specified. In the description of the present invention, it should be understood that the orientations or positional relationships indicated by the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc. are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention.

[0043] In the present invention, unless otherwise expressly specified or limited, when a first feature is "above" or "below" a second feature, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediary. Furthermore, when a first feature is "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0044] See also Figure 2 The sample analyzer 1 of the present invention shown in the figure comprises an instrument body and a casing 30, as well as a sample transport device 17 arranged in front of the instrument body. A first mixing device 11, a conveying device 12 and a control device 21 are also provided inside the casing 30. The sample transport device 17 is used to transport the sample container 92 containing the sample to the mixing position. In the present embodiment, the mixing position is provided in the first mixing device 11. The first mixing device 11 comprises a driving unit 111 and a fixed seat 112, wherein the driving unit has a driving shaft, the fixed seat 112 is fixedly connected to the driving shaft, and the driving unit 111 can drive the fixed seat 112 to rotate via the driving shaft. The fixed seat 112 is used to accommodate the sample container 92 loaded with the sample. The control device 21 is electrically connected to the sample transport device 17, the driving unit 111 and the conveying device 12, and the control device 21 is used to control the coordinated work between the above components.

[0045] In the sample analyzer 1 of the present invention, a display unit 31, operation buttons 32, and operation buttons 33 may also be provided on the housing 30. The display unit 31 may be a touch-operable touch screen, and input devices such as a soft keyboard may be displayed by touching the display unit 31. In other embodiments, the input device may also be provided as independent hardware.

[0046] See also Figure 2-Figure 4 The instrument body may also include a second mixing device, a sample suction device 13, a sample rack 80, a container rotating code scanning device (including a container pressing component 14, a container rotating component 15, a code scanner 16), a sample preparation device (not shown), a detector (not shown), etc. The sample suction device 13 is used to draw blood samples from the sample container 92 after being mixed by the first mixing device 11. The sample rack 80 is used to carry the sample container 92. The container rotating code scanning device is used to obtain the sample coding information on the label of the sample container 92. The sample preparation device is used to prepare the blood sample drawn by the sample suction device 13 into a test sample. The detector is used to detect blood cells in the test sample. The above components can all be electrically connected to the control device 21 of the sample analyzer 1, and the control device 21 coordinates the collaborative work between the components.

[0047] In one embodiment, the sample analyzer 1 may further include a sample chamber assembly 18 for single sample injection of trace blood samples or regular blood samples, which is typically used for measuring emergency queue-jumping samples. The sample chamber assembly 18 has a sample chamber cover 181 and a sample container receiving hole 182. When it is necessary to measure an emergency queue-jumping sample, the sample chamber cover 181 can be opened to place the sample container containing the emergency queue-jumping sample into the sample container receiving hole 182 to fix the sample container 92, or to remove the sample container 92 from the sample container receiving hole 182. The aperture of the sample container receiving hole 182 is slightly larger than the sample container 92 to be placed.

[0048] Figure 5FIG. 1 is a schematic structural diagram of the sample transport device 17 according to an embodiment of the present invention. Figure 5 As shown, the sample transport device 17 includes: a sample rack supporting component 171 , a sample rack feeding device 172 , a sample rack bidirectional transport device 173 , and a sample rack feeding device 174 .

[0049] The sample rack support assembly 171 includes a pre-analysis sample rack storage area 1711 for accommodating a plurality of sample racks 80 holding sample containers containing pre-analysis samples, a post-analysis sample rack storage area 1712 for accommodating a plurality of sample racks 80 holding sample containers containing post-analysis samples, and a sample analysis area (not shown) located between the pre-analysis sample rack storage area 1711 and the post-analysis sample rack storage area 1712. A sample rack infeed diversion area 1711a is located on one side of the pre-analysis sample rack storage area 1711, and a sample rack outfeed diversion area 1712a is located on the other side of the post-analysis sample rack storage area 1712.

[0050] The sample rack feeding device 172 includes sample rack feeding components 1721 and 1722. These components move in the Y2 direction, pushing sample racks 80 stored in the pre-analysis sample rack storage area 1711 one by one into the sample rack feeding diversion area 1711a. These components are driven by a stepper motor. Once the sample racks 80 have entered the sample rack feeding diversion area 1711a, they are transported further in the X1 direction by the sample rack bidirectional transport device 173. The sample container 92 containing the sample entering the analysis area will be transported to the scanning position in turn and scanned by the container rotating scanning device 14~16, and then the sample container 92 delivered to the predetermined position will be transported to the first mixing device 11 or the second mixing device for mixing, and the mixed sample container 92 will be returned to the predetermined position, and then sent to the sampling position, and the blood sample mixed by the first mixing device 11 or the second mixing device will be aspirated from the sample container 92 by the sample aspirator 13, the blood sample aspirated by the sample aspirator 13 will be prepared into a test sample by the sample preparation device, and the blood cells in the test sample prepared by the sample preparation device will be detected by the detector.

[0051] After the sample rack 80 with the sample container containing the sample fixed thereon is transported to the sample rack delivery diversion area 1712a by the sample rack bidirectional sample transport device 173, the sample rack delivery component 1741 of the sample rack delivery device 174 moves horizontally along the Y1 direction to push the sample rack 80 to the post-analysis sample rack storage area 1712.

[0052] It should be noted that blood sample testing typically involves testing micro- or macro-samples. In the sample analyzer 1 of the present invention, the first mixing device 11 typically corresponds to mixing the sample container 92 containing micro-samples. For sample containers containing macro-samples, the aforementioned second mixing device can perform mixing, controlled and transferred by the aforementioned components, with the workflow being substantially the same as that for the sample container 92.

[0053] In one embodiment of the present invention, the control device 21 is configured to control the transport device 12 to transport the sample container 92 transported to the mixing position to the fixed seat 112 of the first mixing device 11. The control device 21 first controls the driving unit 111 to rotate the fixed seat 112 at a first rotation speed ω1 for a first preset time duration T1, thereby causing the sample container 92 contained in the fixed seat 112 to rotate. The control device 21 then controls the driving unit 111 to rotate the fixed seat 112 at a second rotation speed ω2, which is different from the first rotation speed ω1, for a second preset time duration T2, thereby causing the sample container 92 contained in the fixed seat 112 to rotate.

[0054] Please look back Figure 1 As described above, after the anticoagulant is added to the blood sample in sample container 92, due to the different specific gravities of blood cells and plasma, with blood cells having a higher specific gravity, the anticoagulated blood will stratify after a period of stagnant time. The heavier blood cells will settle to the bottom of sample container 92. Conversely, the plasma will float relatively higher in sample container 92. Between the plasma and blood cells, there are also components such as white blood cells and platelets.

[0055] When the fixed seat 112 is driven to rotate by the driving part 111, if the fixed seat 112 always rotates at a relatively high speed, the sample container 92 driven by it also rotates at a fixed speed along with the fixed seat 112. For the vortex mixing method, when it rotates at a fixed speed, the shape of the vortex formed in the sample container 92 is a fixed shape, and the height of the vortex edge relative to the inner wall of the sample container 92 is also a fixed height. In the initial stage of mixing, if sputtering or irregular impact occurs, the plasma in the upper layer may sputter some tiny plasma particles that adhere to the inner wall of the sample container 92. Due to the effect of molecular attraction, these tiny plasma particles adhering to the inner wall of the sample container 92 may not be able to slide back to the bottom of the container. Accordingly, in the subsequent detection process, due to the loss of this part of plasma, the proportion of blood cells in the sample will increase, which will lead to deviations in the test results.

[0056] The present invention controls the driving unit 111 through the control device 21, so that the fixing seat 112 can drive the sample container 92 to rotate at different speeds in the process of mixing the sample in the sample container 92. The duration of each rotation can be the same or different. By rotating at a variable speed, the vortex shape of the sample in the sample container 92 can be changed, and the height of the vortex edge relative to the inner wall of the sample container 92 also changes during the mixing process. For tiny plasma particles that may adhere to the inner wall of the sample container 92, they can be brought back into the sample by the flow of the changed vortex edge relative to the inner wall of the sample container 92, thereby avoiding the loss of this part of the plasma.

[0057] Therefore, under the control of the control device 21 on the driving part 111, the sample analyzer 1 of the present invention successively adopts the first rotation speed ω1 and the second rotation speed ω2 of the fixing seat 112 to drive the sample container 92 to rotate at variable speeds and achieve the purpose of mixing the sample, which can improve the sample mixing effect and reduce the deviation of the detection result caused by mixing.

[0058] See Figure 6 In the embodiment, the first mixing device 11 may further include a bracket 113 and a sensor 114. The bracket 113 is used to fix the driving part 111 and the sensor 114, and Figure 6 In the embodiment, the drive unit 111 is configured as a motor. The motor can be a stepper motor, a DC motor, a servo motor, or other device that can provide rotational power. For the sample analyzer 1 of the present invention, the drive unit 111 is preferably a stepper motor. The sensor 114 is used to detect the motion state of the fixing base 112, including whether the fixing base 112 is rotating and the rotational speed of the fixing base 112.

[0059] Furthermore, the sensor 114 can also be communicatively connected to the control device to transmit the rotational state of the fixing base 112 to the control device. The control device can then adjust the rotational speed of the driving unit 111 based on the rotational state of the fixing base 112. The control device can also further determine whether the first mixing device 11 is faulty, such as whether the fixing base 112 is stuck, based on the rotational state of the fixing base 112. For example, when the sensor 114 detects that the rotational speed of the sample container holder is zero during the mixing operation, the control device can determine that the first mixing device 11 has failed, such as when the control device fails to successfully activate the driving unit 111, or when the connection between the fixing base 112 and the driving unit 111 is disconnected, or when the fixing base 112 is stuck. Alternatively, when the rotational speed of the fixing base 112 detected by the sensor 114 is less than a predetermined speed, the control device can also determine that the first mixing device 11 has failed, such as when the connection between the fixing base 112 and the driving unit 111 is loose, causing slippage and a decrease in speed.

[0060] The sample container holder 112 is rotationally connected to the stepper motor 111. The holder 112 can be directly fixed to the rotating shaft of the motor 111, or it can be indirectly rotationally connected to the rotating shaft of the motor 111, such as through a belt, a synchronous belt, a gear set, etc., or the motor 111 drives a rotating wheel with an elastic peripheral washer, and the peripheral washer contacts the periphery of the sample container holder 112 to provide friction, thereby rotating the sample container holder 112. Among them, directly fixing the sample container holder 112 to the rotating shaft of the motor 111 is the preferred embodiment of the present application.

[0061] like Figure 6 and Figure 7 As shown, a receiving cavity 1121 is provided on the top of the fixing base 112, and the receiving cavity 1121 can be placed in a sample container 92 containing a sample. The sample container 92 can be a constant sample container for accommodating venous blood or a micro sample container for accommodating peripheral blood.

[0062] like Figure 7 As shown, the lower portion of the fixing base 112 is provided with a sensing portion 1122 corresponding to the sensor 114, and a notch 1123. When the fixing base 112 rotates, the sensing portion 1122 and the notch 1123 will alternately enter the sensing area of ​​the sensor 114. The sensing area of ​​the sensor 114 will alternately switch between the blocking state and the non-blocking state, and the output terminal of the sensor 114 will output the corresponding Figure 8 By detecting the pulses shown in (a) or (b), whether the fixed base 112 rotates can be determined by detecting whether the sensor 114 outputs a pulse signal. By detecting the number of pulse signals output by the sensor 114, it can be known whether the number of rotations of the fixed base 112 meets expectations. By detecting the signal period T of the pulse signal shown, it can be calculated whether the rotation speed of the fixed base 112 meets expectations.

[0063] Another embodiment of the first mixing device 11 can be found in Figure 9The sample container 92 can also be placed tilted in the accommodating cavity 1121 of the fixing base 112. An abutment portion 122 is provided at the bottom of the accommodating cavity 1121. The abutment portion 122 is configured such that when the sample container 92 is accommodated in the accommodating cavity 1121, the sample container 92 abuts against the abutment portion 122, so that the central axis A3 of the sample container 92 forms an acute angle with the rotation axis A1 of the fixing base 112, or in other words, the rotation axis A1 of the sample container 92. In particular, the intersection point P of the projection lines of the central axis A3 of the sample container 92 and the rotation axis A1 of the fixing base 112 in the vertical plane is located above the bottom of the sample accommodating cavity of the sample container 92. By tilting the central axis of the sample container 92 accommodated in the fixing base 112 relative to the rotation axis of the fixing base 112, the fixing base 112 can better meet the sample mixing requirements when driving the sample container 92 therein to rotate. In addition, by adjusting the tilt angle between the central axis of the sample container and the rotation axis of the fixing base, the liquid level of the sample to be mixed can be controlled during rotation, thereby preventing the sample to be mixed from overflowing from the sample container.

[0064] In one embodiment of the present invention, the second mixing device is part of the transport device 12. The transport device 12 can not only transport sample containers containing micro-samples to the first mixing device 11 for mixing, but also mix sample containers containing normal blood samples.

[0065] The sample mixing method provided by the present invention is described in detail below. The sample mixing method is applied to the above-mentioned sample analyzer, for example.

[0066] See Figure 10 The sample mixing method provided by the present invention includes the following steps:

[0067] S10, placing the sample container 92 loaded with the sample into the fixing seat 112 of the sample mixing device (here, for example, the first mixing device 11);

[0068] S20, first controlling the driving portion 111 of the sample mixing device 11 to drive the fixing base 112 to rotate at a first rotation speed ω1 for a first preset time period T1, so as to drive the sample container 92 contained in the fixing base 112 to rotate;

[0069] S30 , controlling the driving unit 111 to drive the fixing base 112 to rotate at a second rotation speed ω2 different from the first rotation speed ω1 for a second preset time period T2 , so as to drive the sample container 92 contained in the fixing base 112 to rotate.

[0070] In one embodiment, the sample mixing method provided by the present invention has the same configuration and function as the control device 21 described above, or can be described as the control device 21 configured to perform the sample mixing method of the present invention. Its function is also to drive the sample container 92 to rotate at a variable speed via the fixing base 112 and perform mixing.

[0071] In one embodiment of the sample mixing method of the present invention, the first rotational speed ω1 is set to be less than the second rotational speed ω2. Specifically, the holder 112 first rotates the sample container 92 at a low speed for a first preset time duration T1, and then rotates the sample container 92 at a high speed for a second preset time duration T2. ​​This low-to-high-speed mixing method allows the blood cells and plasma of the stratified blood sample in the sample container 92 to initially exchange at a low rotational speed. Due to the low rotational speed of the holder 112, the blood cells and plasma cannot be fully mixed. Consequently, the probability of sample splashing within the sample container 92 is also reduced. After the sample container 92 rotates for the first preset time period T1, the rotation speed of the fixing base 112 is increased, so that the exchange efficiency of blood cells and plasma is gradually improved, and the blood cells and plasma in the blood sample gradually tend to be uniform. Although the probability of the sample splashing in the sample container 92 gradually increases after the fixing base 112 is accelerated, compared with the method of directly using the second rotation speed ω2 for uniform mixing, in the sample mixing method of the present invention, because the sample in the sample container 92 is already close to uniform, even if tiny blood sample particles splash onto the inner wall of the sample container 92 and cannot slide back to the bottom of the container, it will not significantly affect the change in the proportion of blood cells and plasma in the blood. Therefore, the probability and amplitude of deviation in blood sample test results caused by mixing can be reduced.

[0072] In one embodiment of the present invention, after step S30, the sample mixing method of the present invention may include the following steps:

[0073] End the mixing operation; or

[0074] The driving unit 111 is continuously controlled to drive the fixing base 112 at a rotation speed different from the second rotation speed ω2, so as to drive the sample container contained therein to rotate.

[0075] In one embodiment of the present invention, see Figure 11 Step S20 includes repeating the following steps at least once:

[0076] S21, first control the driving unit 111 to drive the fixing base 112 to rotate at the first rotation speed ω1 for a period of time;

[0077] S22 , then controlling the driving unit 111 to stop driving the fixing seat 112 .

[0078] Specifically, in this embodiment, after controlling the driving unit 111 to rotate the fixing base 112 at the first rotational speed ω1 for a period of time, the driving of the fixing base 112 is stopped. This stopping allows the sample that has climbed to the inner wall of the sample container's sample cavity due to the vortex centrifugal action in step S21 to flow back to the bottom of the sample container's sample cavity. By performing at least one sample climbing action step S21 and sample backflow action step S22, the sample mixing effect can be improved.

[0079] On the other hand, the "rotation for a period of time" in step S21 can be defined as "rotation for the first time period t1". The first time period t1 needs to meet the condition: t1 <= T1 (first preset duration). It can be understood that when this step is repeated multiple times, the sum of multiple first time periods t1 is equal to the first preset duration T1. And each time the driving unit 111 drives the fixed seat 112 to rotate the first time period t1 at the first speed ω1, it is necessary to control the fixed seat 112 to pause for the first interval time Δt1. The duration settings of multiple first time periods t1 can be set to be the same or different. And the first interval time Δt1 between two adjacent first time periods t1 of rotation can also be set to be the same or different, and the present invention does not specifically limit this.

[0080] Likewise, in one embodiment, see Figure 11 Step S30 may also include repeating the following steps at least once:

[0081] S31, first control the driving unit 111 to drive the fixing base 112 to rotate at the second rotation speed ω2 for a period of time;

[0082] S32 , controlling the driving unit 111 to stop driving the fixing seat 112 .

[0083] Specifically, in this embodiment, after controlling the driving unit 111 to rotate the fixing base 112 at the second rotational speed ω2 for a period of time, the driving of the fixing base 112 is stopped. This stopping also allows the sample that has climbed to the inner wall of the sample container's sample cavity due to the vortex centrifugal action in step S31 to flow back to the bottom of the sample container's sample cavity. By performing at least one sample climbing action step S31 and sample backflow action step S32, the sample mixing effect can be improved.

[0084] It can be understood that the "rotation for a period of time" in step S31 can be defined as "rotation for a second period t2". The second period t2 also needs to meet the condition: t2 <= T2 (second preset duration). When S31 and step 32 are cycled multiple times, the sum of multiple second periods t2 is equal to the second preset duration T2. ​​And each time the driving unit 111 drives the fixed seat 112 to rotate the second period t2 at the second speed ω2, it is also necessary to control the fixed seat 112 to pause for the second interval time Δt2. The duration settings of multiple second periods t2 can be set to be the same or different. And the second interval time Δt2 between two adjacent rotations of the second period t2 can also be set to be the same or different, and the present invention does not specifically limit this.

[0085] In addition, the first time period t1 and the second time period t2 may be the same or different, and Δt1 and Δt2 may be the same or different, which is not particularly limited in the present invention.

[0086] Furthermore, a counter may be used to record the number of repetitions of step S21 and step S23, so that after step S21 and step S23 are repeated a preset number of times, the driving unit 111 is controlled to drive the fixing base 112 at the second rotational speed ω2. Similarly, the counter may also record the number of repetitions of step S21 and step S23, so that after step S21 and step S23 are repeated a preset number of times, the mixing operation is terminated or the driving unit 111 is controlled to continue driving the fixing base 112 at a rotational speed different from the second rotational speed ω2.

[0087] For details, see Figure 11 , after step S10, the process includes step S11: the control device 21 clears a counter for recording the number of mixing times.

[0088] Then, steps S21 and S22 are implemented, and after step S22, step S23 is included: the value of the counter for recording the number of mixing times is increased by 1.

[0089] Then, it is determined whether the mixing times have reached the first preset mixing times. If not, steps S21 to S23 are continuously implemented.

[0090] If the driving unit 111 repeatedly drives the fixing base 112 at the first rotation speed ω1 and stops driving for a number of times reaching a first preset mixing number, the driving unit 111 starts to drive the fixing base 112 at the second rotation speed ω2.

[0091] Therefore, by recording the number of times the driving unit 111 repeatedly drives the fixing seat 112 at the first rotational speed ω1 and stops driving through a counter, it is possible to achieve the effect of "controlling the driving unit 111 of the sample mixing device 11 to drive the fixing seat 112 to rotate at the first rotational speed ω1 for the first preset time length T1" by pre-setting a fixed first preset mixing number.

[0092] Similarly, before starting to control the driving part 111 to drive the fixing base 112 at the second rotation speed ω2, step S12 is also included, in which the control device 21 clears the counter for recording the number of mixing times.

[0093] Then, steps S31 and S32 are implemented, and after step S32, step S33 is included: the value of the counter for recording the number of mixing times is increased by 1.

[0094] Then, it is determined whether the mixing times reaches a second preset mixing times. If not, steps S31 to S33 are continuously implemented.

[0095] If the driving unit 111 repeatedly drives the fixing base 112 at the second rotation speed ω2 and stops driving for a number of times reaching a second preset mixing number, the mixing operation is terminated or the driving unit 111 is continuously controlled to drive the fixing base 112 at a rotation speed different from the second rotation speed ω2.

[0096] By recording the number of times the driving unit 111 repeatedly drives the fixing seat 112 at the second rotational speed ω2 and stops driving through a counter, it is possible to achieve the effect of "controlling the driving unit 111 of the sample mixing device 11 to drive the fixing seat 112 to rotate at the second rotational speed ω2 for the second preset time length T2" by pre-setting a fixed second preset mixing number.

[0097] In some embodiments of the present invention, the first preset mixing times are the same as or different from the second preset mixing speed, that is, the first preset time length T1 and the second preset time length T2 are the same as or different, which is not limited in the present invention.

[0098] In some embodiments of the present invention, a timer may be used instead of the above-mentioned counter, that is, the preset duration in steps S20 and / or S30 may be achieved by controlling the driving unit 111 to drive the fixing seat 112 at the first rotation speed ω1 and / or the second rotation speed ω2 for the mixing time rather than the mixing times.

[0099] In one embodiment of the present invention, Figure 12 As shown, when the driving unit 111 is controlled to drive the fixing seat 112 to rotate at the first rotation speed ω1 and / or the second rotation speed ω2, the method may further include:

[0100] S24 / S34, detecting the actual rotation speed of the fixing seat 112;

[0101] When the fixing base 112 is judged to be abnormal according to the detected actual rotation speed, it is prompted that the first mixing device 11 is abnormal and / or the mixing operation of the sample container 92 is terminated.

[0102] Understandably, combined with the above Figure 8 The output pulse of sensor 114 shown is detected. By detecting whether sensor 114 outputs a pulse signal, it can be determined whether the fixed base 112 is rotating. By detecting the number of pulse signals output by sensor 114, it can be determined whether the number of rotations of fixed base 112 meets the expectations. By detecting the signal period T of the pulse signal shown, it can be calculated whether the rotation speed of fixed base 112 meets the expectations. However, if the actual rotation speed of fixed base 112 detected is abnormal, the mixing operation may not achieve the expected effect. Therefore, it is necessary to issue a prompt or terminate the mixing operation in a timely manner, and then continue the mixing operation in an orderly manner after the fault is eliminated, to reduce the risk of insufficient mixing or even no mixing of the sample.

[0103] In one embodiment of the present application, the method of the present invention may further include step S40 after step S30: controlling the driving unit 111 to drive the fixing seat 112 to rotate at a third rotation speed ω3 different from the second rotation speed ω2 for a third preset time period to drive the sample container 92 contained therein to rotate.

[0104] In one embodiment, the third rotational speed ω3 may be lower than the second rotational speed ω2, that is, the fixing base 112 is driven alternately in a "low speed-high speed-low speed" cycle to rotate the sample container 92 for sample mixing. After the driving unit 111 drives the fixing base 112 at the third rotational speed ω3 for a third predetermined time period, the fixing base 112 may be further driven at a fourth, fifth, and so on rotational speeds different from the third speed to facilitate sample mixing.

[0105] In one embodiment, the third rotational speed ω3 is preferably greater than the second rotational speed ω2, that is, the fixed base 112 is driven to rotate the sample container 92 in a gradually accelerating manner to perform the sample mixing operation. During the entire process of the first mixing device 11 mixing the sample container 92, in order to achieve a better mixing effect, more precise control of the mixing process is required. Specifically, multiple accelerations are performed to gradually reach the preset mixing speed, and finally the entire mixing operation is completed, thereby avoiding effects such as sputtering that may be caused by excessively rapid speed increases.

[0106] Therefore, it can be understood that in some embodiments of the present invention, before step S40, it is further included to determine whether the second speed ω2 is less than the preset maximum speed ωmax, such as Figure 13 As shown:

[0107] S41, if the second rotational speed ω2 is less than the preset maximum rotational speed ωmax, continue to control the driving unit 111 to drive the fixing base 112 to rotate at a third rotational speed ω3 different from the second rotational speed ω2, so as to drive the contained sample container 92 to rotate;

[0108] S42 : If the second rotation speed ω2 is greater than or equal to the preset maximum rotation speed ωmax, the driving unit 111 is controlled to stop driving the fixing seat 112 , so as to end the mixing operation of the sample container 92 .

[0109] Specifically, a preset maximum rotational speed ωmax is used to determine whether the sample mixing device 11 has completed the mixing operation of the sample container 92 according to preset requirements. That is, when the rotational speed of the fixing base 112 driven by the driving unit 111 reaches the preset maximum rotational speed ωmax, it is considered that the sample mixing device 11 has achieved the preset mixing requirements for the sample container 92. After the sample container 92 is mixed at the preset maximum rotational speed, the sample contained therein is fully mixed and meets the requirements of sample testing.

[0110] Preferably, the first rotation speed ω1 is less than the second rotation speed ω2, and the second rotation speed ω2 is less than the third rotation speed ω3. In other words, by gradually increasing the speed of each rotation of the fixing base 112, the preset maximum rotation speed ωmax is gradually reached through multiple accelerations to complete the entire mixing operation.

[0111] It should be noted that in this embodiment, the amplitude Δω of each rotational speed increase of the driving unit 111 can be a fixed value, or the amplitude Δω can vary each time. That is, the difference between the second rotational speed ω2 and the first rotational speed Δω1, and the difference between the third rotational speed ω3 and the second rotational speed ω2, can be the same or different. The specific adjustment is based on actual needs and is not limited by the present invention.

[0112] On the other hand, to achieve a step-by-step acceleration mixing method, the present mixing method does not limit the holder 112 to reaching or exceeding the preset maximum speed ωmax after reaching the third speed ω3. Based on the adjustment of the speed increase amplitude Δω, a fourth speed ω4, a fifth speed ω5, and so on can be set after the third speed ω3 to achieve the purpose of gradually reaching the preset maximum speed ωmax after multiple accelerations and performing a mixing operation on the sample container 92.

[0113] Based on the development of the above embodiments, it can be obtained that Figure 14 As shown in the mixing flow chart, the sample analyzer 1 of the present invention completes the mixing operation of the sample container 92 in a step-by-step acceleration manner by configuring the control device 21. Figure 14 As shown, the following steps are included:

[0114] In step S101 , the sample container 92 is placed into the sample container receiving cavity 1121 of the fixing base 112 of the sample mixing device 111 by the transport device 12 or manually.

[0115] In step S102, before starting to mix the sample, the control device first resets the counter used to record the number of mixing times;

[0116] In step S103, the control device controls the driving portion of the sample mixing device 11, such as the motor 111, to first drive the fixing base 112 at a relatively low rotation speed ω to rotate the sample container 92, thereby forming a vortex in the sample container;

[0117] In step S104, while the driving unit 111 drives the fixing base 112 to rotate, the control device monitors the output signal of the sensor 114 to determine one or more of whether the fixing base 12 rotates, whether the number of rotations meets expectations, and whether the rotation speed meets expectations;

[0118] In step S105, when the control device detects abnormal rotation of the fixing base 12 by monitoring the output signal of the sensor 114, the mixing process is terminated in advance, otherwise the process jumps to step S106;

[0119] In step S106, after the driving unit 111 drives the fixing base 112 to rotate for a period of time, the control device controls the driving unit 111 to pause for a period of time. This pause allows the sample that climbed to the inner wall of the sample cavity of the sample container due to the vortex centrifugal effect in step S103 to flow back to the bottom of the sample cavity of the sample container. The sample climbing in step S103 and the sample backflow in step S106 promote mixing of the sample.

[0120] In step S107, the counter counts +1, and records that one mixing is completed;

[0121] In step S108, it is determined whether the number of mixing operations at the rotational speed ω has reached a preset value. If so, the process proceeds to step S109; otherwise, the process proceeds to step S103 to perform another mixing operation at the rotational speed ω.

[0122] In step S109, it is determined whether the current rotation speed ω has reached the preset maximum angular velocity. If so, the process ends normally. If not, it jumps to step S110;

[0123] In step S110 , the control device resets the rotation speed of the driving portion 111 so that the rotation speed of the driving portion 111 increases by Δω, and then returns to step S102 to mix the sample at the new angular velocity ω.

[0124] In one embodiment of the present invention, see Figure 15Step S20 further includes repeating the following steps at least once:

[0125] S21a, first control the driving unit 111 to drive the fixing base 112 to rotate along the first rotation direction for a period of time at the first rotation speed ω1;

[0126] S22a, controlling the driving unit 111 to drive the fixing base 112 to rotate at the first rotation speed ω1 along a second rotation direction opposite to the first rotation direction for a period of time.

[0127] In this embodiment, the concept of rotation direction is introduced. For the sake of ease of description, the rotation direction of the sample container 92 driven by the driving seat 112 can be defined as two opposite directions, forward and reverse. In step S21a, the driving unit 111 is first controlled to drive the fixed seat 112 to rotate in the forward direction (first rotation direction) for a period of time at the first rotation speed ω1, and then in step S22a, the driving unit 111 is controlled to drive the fixed seat 112 to rotate in the reverse direction (second rotation direction) for a period of time at the first rotation speed ω1. Although the rotation speeds controlled before and after are both the first rotation speed ω1, because the sample container 92 actually undergoes both forward rotation mixing and reverse rotation mixing, the sample in the sample container 92 can obtain a better mixing effect. After implementing the above steps multiple times, the mixing effect of the sample container 92 will be better than the mixing effect of always rotating in the same rotation direction.

[0128] Likewise, see Figure 16 Step S30 may also include repeating the following steps at least once:

[0129] S31a, first control the driving unit 111 to drive the fixing base 112 to rotate along the first rotation direction for a period of time at the second rotation speed ω2;

[0130] S32a, controlling the driving unit 111 to drive the fixing base 112 to rotate at a second rotation speed ω2 for a period of time in a second rotation direction opposite to the first rotation direction.

[0131] Similar to the effects of steps S21a and S22a above, when the driving seat 112 drives the sample container 92 to rotate at the second rotation speed ω2, the sample in the sample container 92 can also be better mixed by changing the rotation direction of the fixing seat 112.

[0132] It will be appreciated that, for the aforementioned embodiment in which the fixing base 112 is reversed in rotation, before the driving unit 111 is controlled to drive the fixing base 112 to change its rotational direction, the step of controlling the driving unit 111 to stop driving the fixing base 112 may also be included, so that the sample in the sample container 92 contained in the fixing base 112 can flow back to the bottom of the fixing base 112. If the rotational direction of the rotating sample container 92 is changed in a short period of time, it is easy to cause significant splashing of the sample inside the sample container 92, thereby causing a large amount of sample to adhere to the inner wall of the sample container 92 or even fly out of the sample container 92, making it difficult for the sample to flow back to the bottom of the sample container 92, resulting in sample loss. Therefore, before each change in the rotational direction of the fixing base 112, the driving action of the fixing base 112 is stopped, so that the fixing base 112 slows down or stops its rotation, allowing the sample in the sample container 92 to completely fall back to the bottom of the cavity, thereby avoiding sample loss and facilitating sample mixing.

[0133] Based on the development of the above embodiments, we can also get Figure 17 The sample analyzer 1 of the present invention completes the mixing operation of the sample container 92 in the form of step-by-step acceleration and reversal by configuring the control device 21. It should be pointed out that Figure 17 In the embodiment, the forward and reverse mixing actions S203a and S203b of the fixing seat 112 can be defined as two mixings, and the number of mixing times on the counter is counted as "+2". Figure 17 The steps S201, S202, S204 to S210 shown in FIG. Figure 14 The description is not repeated here.

[0134] See Figure 18 Another embodiment of the sample mixing method provided by the present invention includes:

[0135] S10b, placing the sample container 92 loaded with the sample into the fixing seat 112 of the sample mixing device 11;

[0136] S20b, first controlling the driving portion 111 of the sample mixing device 11 to drive the fixing base 112 to rotate along a first rotation direction for a first preset time period T1 at a first rotation speed ω1, thereby driving the sample container 92 contained in the fixing base 112 to rotate;

[0137] S30b, controlling the driving unit 111 to drive the fixing base 112 to rotate at a second rotational speed ω2 different from the first rotational speed ω1 for a second preset time period T2 in a second rotational direction opposite to the first rotational direction, so as to rotate the sample container 92 contained in the fixing base 112.

[0138] Similar to the above embodiment, Figure 18The provided sample mixing method also improves the sample mixing effect in the sample container 92 by reversing the fixing seat 112 .

[0139] It can be understood that the control device 21 of the sample analyzer 1 is configured to implement the sample mixing method of the present invention described above, so as to obtain a better mixing effect, thereby ensuring the accuracy of sample analysis and detection.

[0140] See Figure 19 The present invention also provides another sample mixing method, comprising the following steps:

[0141] S191, placing the sample container 92 loaded with the sample into the fixing seat 112 of the sample mixing device 11;

[0142] S192. Control the driving portion 111 of the sample mixing device 11 to drive the fixing base 112 to move in a manner that its driving speed gradually increases from an initial speed V0 to a preset maximum speed Vmax, so as to drive the sample container 92 contained in the fixing base 112 to move, thereby mixing the sample in the sample container 92.

[0143] exist Figure 19 The sample mixing method shown utilizes variable speed mixing to mix the sample within the sample container 92 to achieve a better mixing effect. For example, in the vortex mixing method, this method controls the variable speed mixing process by gradually increasing the driving speed of the driving unit 111 from an initial speed V0 to a preset maximum speed Vmax to drive the fixed base 112 to move. The sample container 92 achieves the mixing operation during the continuously accelerated rotation.

[0144] exist Figure 19 The sample mixing method shown is not limited to rotational mixing. By coordinating the structure and transmission method of the drive unit 111 and the fixed base 112, vibration, swinging, and other methods may also be used to mix the sample container 92. It will be appreciated that, similar to vortex mixing, mixing through vibration, swinging, and other methods can also achieve better mixing effects due to the gradual increase in mixing speed, thereby ensuring the accuracy of the test results of sample analysis 1.

[0145] This method further improves the effect of the mixing operation. Since the initial speed V0 is usually small, the sample in the sample container 92 can also achieve a certain initial exchange effect at the beginning of the mixing operation, and the exchange effect is continuously improved during the gradual acceleration process, and finally tends to a uniform sample shape.

[0146] It is understood that during the implementation of the present method, the process of controlling the driving portion 111 of the first mixing device 11 to gradually increase its driving speed from an initial speed V0 to a preset maximum speed Vmax to drive the fixed seat 112 to move may also include first controlling the driving portion 111 to drive the fixed seat 112 to move at a first driving speed for a first preset time period T01; and then controlling the driving portion 111 to drive the fixed seat 112 to move at a second driving speed different from the first driving speed for a second preset time period T02. That is, while the driving portion 111 gradually accelerates the movement (rotation, vibration, or swinging) of the fixed seat 112, it may also maintain a certain movement rate (the first driving speed or the second driving speed) for a certain time period (the first preset time period T01 or the second preset time period T02) to mix the sample in the sample container 92 from a low speed to a high speed.

[0147] Maintaining a fixed motion rate for the mixing operation facilitates control of the drive unit 111 by the control device 21. In scenarios where a certain total mixing duration is required, maintaining the drive unit 111 in a constant accelerated motion of the fixed seat 112 requires a high level of control precision from the control device 21. However, by introducing a first preset duration T01 corresponding to the first drive speed and a second preset duration T02 corresponding to the second drive speed, the control precision of the control device 21 can be appropriately reduced, allowing the drive unit 111 to only drive the fixed seat 112 at a fixed motion rate for a certain duration. This achieves the goal of both meeting the total mixing duration and reducing the control precision of the control device 21.

[0148] It is understandable that the above embodiments of the counter and sensor 114 detecting the motion state of the fixed base 112 and providing prompts and alarms and alternating forward and reverse rotation can also be applied to Figure 18 The mixing method comes from the above, which will not be described here.

[0149] On the other hand, another sample analyzer 1 according to the present invention may also include the above-mentioned sample transport device 17, the first mixing device 11, the conveying device 12, the control device 21, etc. The sample transport device 17 is used to transport the sample container 92 loaded with the sample to the mixing position, and the first mixing device 11 includes a driving portion 111 having a driving shaft and a fixing seat 1112 fixedly connected to the driving shaft 111. The driving portion 111 is used to drive the fixing seat 112 to rotate through its driving shaft, and the fixing seat 112 is used to fixedly accommodate the sample container 92 loaded with the sample. The conveying device 12 is used to transport the sample container 92 to the fixing seat 112 of the first mixing device 11. The control device 21 is electrically connected to the sample transport device 17, the driving portion 111 and the conveying device 12. The control device 21 is configured to control the conveying device 12 to transport the sample container 92 transported to the mixing position to the fixing seat 112 of the first mixing device 11.

[0150] Furthermore, the control device 21 is also configured to implement Figure 18 The sample mixing method shown is as follows: the driving unit 111 is controlled to drive the fixing base 112 to move in a manner that its driving speed gradually increases from an initial speed V0 to a preset maximum speed Vmax, so as to drive the sample container 92 contained in the fixing base 112 to move, thereby mixing the sample in the sample container 92.

[0151] See Figure 20 The present invention relates to a computer-readable storage medium 200. The computer-readable storage medium 200 includes a processor 201 and a storage device 202. The storage device 202 stores executable instructions configured to cause the processor 201 to execute the executable instructions to implement the above-mentioned sample mixing method.

[0152] The storage device 202 may include a volatile memory device (volatile memory), such as a random-access memory device (RAM), or a non-volatile memory device (non-volatile memory), such as a flash memory device (flash memory), a solid-state drive (SSD), or a combination of the above types of storage devices.

[0153] The processor 201 may be a central processing unit (CPU). The processor 201 may also be other general-purpose processors, digital signal processors (DSP), application-specific integrated circuits (ASIC), field-programmable gate arrays (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. The general-purpose processor may be a microprocessor or any conventional processor.

[0154] In one embodiment, the processor 201 calls the program instructions stored in the storage device 202 to perform the following operations:

[0155] Place the sample container 92 loaded with the sample into the fixing seat 112 of the sample mixing device 11;

[0156] First, the driving portion 111 of the sample mixing device 11 is controlled to drive the fixing base 112 to rotate at a first rotation speed ω1 for a first preset time period T1, thereby driving the sample container 92 contained in the fixing base 112 to rotate;

[0157] Then, the driving unit 111 is controlled to drive the fixing base 112 to rotate at a second rotation speed ω2 different from the first rotation speed ω1 for a second preset time period T2, so as to drive the sample container 92 contained in the fixing base 112 to rotate.

[0158] In one embodiment, the processor 201 calls the program instructions stored in the storage device 202 to perform the following operations:

[0159] Place the sample container 92 loaded with the sample into the fixing seat 112 of the sample mixing device 11;

[0160] The driving unit 111 controls the sample mixing device 11 to drive the fixing base 112 to move in a manner that its driving speed gradually increases from an initial speed V0 to a preset maximum speed Vmax, thereby driving the sample container 92 contained in the fixing base 112 to move, thereby mixing the sample in the sample container 92.

[0161] For other embodiments of the computer-readable storage medium of the present invention, reference may be made to the above description of the sample mixing method provided by the present invention, which will not be repeated here.

[0162] The above-mentioned features can be combined with each other in any way as long as they are meaningful within the scope of the present invention. The advantages and features described for each aspect of the sample mixing method are applicable in a corresponding manner to the corresponding sample analyzer and the corresponding computer-readable storage medium, and vice versa.

[0163] The above-described embodiments do not constitute a limitation on the scope of protection of this technical solution. Any modifications, equivalent replacements, and improvements made within the spirit and principles of the above-described embodiments shall be included in the scope of protection of this technical solution.

Claims

1. A sample mixing method, comprising the following steps: placing a sample container loaded with the sample into a fixing seat of the sample mixing device; First, controlling the driving portion of the sample mixing device to drive the fixing base to rotate at a first rotational speed for a first preset time period, thereby driving the sample container accommodated in the fixing base to rotate, so that the sample in the sample container is mixed in the fixing base driven by the first rotational speed; The driving unit is then controlled to drive the fixing base to rotate at a second rotational speed different from the first rotational speed for a second preset time period, so as to drive the sample container accommodated in the fixing base to rotate, so that the sample in the sample container is mixed in the fixing base driven by the second rotational speed.

2. The sample mixing method according to claim 1, characterized in that: The first rotational speed is lower than the second rotational speed.

3. The sample mixing method according to claim 1, characterized in that: The step of controlling the driving unit of the sample mixing device to drive the fixing base to rotate at a first speed for a first preset time period includes repeating the following steps at least once: First, the driving unit is controlled to drive the fixing seat to rotate at a first speed for a period of time; Then, the driving part is controlled to stop driving the fixing seat.

4. The sample mixing method according to claim 1, characterized in that: The controlling the driving unit to drive the fixing base to rotate at a second speed for a second preset time period includes repeating the following steps at least once: First, controlling the driving unit to drive the fixing seat to rotate at a second speed for a period of time; Then, the driving unit is controlled to stop driving the fixing seat.

5. The sample mixing method according to any one of claims 1 to 4, characterized in that: The step of controlling the driving unit of the sample mixing device to drive the fixing base to rotate at a first speed for a first preset time period includes repeating the following steps at least once: First, the driving unit is controlled to drive the fixing base to rotate along a first rotation direction for a period of time at the first rotation speed, and then the driving unit is controlled to drive the fixing base to rotate along a second rotation direction opposite to the first rotation direction for a period of time at the first rotation speed.

6. The sample mixing method according to any one of claims 1 to 4, characterized in that: The controlling the driving unit to drive the fixing base to rotate at a second speed for a second preset time period includes repeating the following steps at least once: First, the driving unit is controlled to drive the fixing base to rotate along the first rotation direction at the second rotation speed for a period of time, and then the driving unit is controlled to drive the fixing base to rotate along the second rotation direction opposite to the first rotation direction at the second rotation speed for a period of time.

7. The sample mixing method according to any one of claims 1 to 4, characterized in that: The step of controlling the driving unit of the sample mixing device to drive the fixing seat to rotate at a first speed for a first preset time period includes: Controlling the driving unit to drive the fixing seat to rotate along the first rotation direction at the first rotation speed for a first preset time period; The controlling the driving unit to drive the fixing seat to rotate at a second speed for a second preset time period includes: The driving unit is controlled to drive the fixing seat to rotate at the second rotation speed along a second rotation direction opposite to the first rotation direction for a second preset time period.

8. The sample mixing method according to claim 5, characterized in that: Before controlling the driving unit to drive the fixing seat to change the rotation direction, the method further includes: The driving unit is controlled to stop driving the fixing seat, so that the sample in the sample container accommodated in the fixing seat flows back to the bottom thereof.

9. The sample mixing method according to any one of claims 1 to 4, characterized in that: When controlling the driving unit to drive the fixing seat to rotate, the method includes: detecting an actual rotation speed of the fixing seat; When the fixing seat is judged to be abnormal according to the detected actual rotation speed, the sample mixing device is prompted to be abnormal and / or the mixing operation of the sample container is terminated.

10. The sample mixing method according to any one of claims 1 to 4, characterized in that: The method further includes: after controlling the driving unit to drive the fixing base to rotate at the second rotation speed for a second preset time period, controlling the driving unit to drive the fixing base to rotate at a third rotation speed different from the second rotation speed to drive the sample container contained therein to rotate.

11. The sample mixing method according to any one of claims 1 to 4, characterized in that: After controlling the driving unit to drive the fixing seat to rotate at the second speed for a second preset time period, the method further includes: If the second rotational speed is less than a preset maximum rotational speed, the driving unit is controlled to continue to drive the fixing base to rotate at a third rotational speed different from the second rotational speed, so as to drive the sample container contained therein to rotate; If the second rotation speed is greater than or equal to a preset maximum rotation speed, the driving unit is controlled to stop driving the fixing seat to end the mixing operation of the sample container.

12. The sample mixing method according to claim 10, characterized in that: The second rotational speed is lower than the third rotational speed.

13. A sample mixing method, comprising the following steps: placing a sample container loaded with the sample into a fixing seat of the sample mixing device; The driving portion of the sample mixing device is controlled to drive the fixing base to move in a manner that its driving speed gradually increases from an initial speed to a preset maximum speed, so as to drive the sample container contained in the fixing base to move, thereby performing a mixing operation on the sample in the sample container, wherein: First, control the driving unit to drive the fixing base to move at a first driving speed for a first preset time period; The driving unit is then controlled to drive the fixing base to move for a second preset time period at a second driving speed different from the first driving speed.

14. A sample analyzer, characterized in that: include: A sample transport device, used for transporting a sample container loaded with a sample to a mixing position; The sample mixing device comprises a driving portion having a driving shaft and a fixing base fixedly connected to the driving shaft, wherein the driving portion is used to drive the fixing base to rotate via the driving shaft, and the fixing base is used to accommodate a sample container loaded with a sample; A transport device, used for transporting the sample container to a fixing seat of the sample mixing device; A control device is electrically connected to the sample transport device, the drive unit, and the transport device, and is configured to: Controlling the transport device to transport the sample container transported to the mixing position to the fixing seat of the sample mixing device; First, the driving unit is controlled to drive the fixing base to rotate at a first rotational speed for a first preset time period, thereby driving the sample container contained in the fixing base to rotate, so that the sample in the sample container is mixed in the fixing base driven by the first rotational speed; The driving unit is then controlled to drive the fixing base to rotate at a second rotational speed different from the first rotational speed for a second preset time period, so as to drive the sample container accommodated in the fixing base to rotate, so that the sample in the sample container is mixed in the fixing base driven by the second rotational speed.

15. The sample analyzer according to claim 14, characterized in that: The driving unit is configured as a motor.

16. The sample analyzer according to claim 14, wherein: The sample mixing device further includes a sensor, which is used to detect the movement state of the fixing seat.

17. The sample analyzer according to any one of claims 14 to 16, characterized in that: Also includes a second mixing device; The sample mixing device is used to mix the sample container when the sample container at the mixing position contains a trace amount of blood sample, and the second mixing device is used to mix the sample container when the sample container at the mixing position contains a constant amount of blood sample.

18. The sample analyzer according to any one of claims 14 to 16, characterized in that: Also includes: a sample aspirating device, used for aspirating the mixed blood sample from the sample container; The sample preparation device is used to prepare the blood sample aspirated by the sample aspirating device into a test sample.

19. The sample analyzer according to any one of claims 14 to 16, characterized in that: The control device is further configured to implement the method of claim 2 or 13.

20. A sample analyzer, characterized in that: include: A sample transport device, used for transporting a sample container loaded with a sample to a mixing position; The sample mixing device comprises a driving portion having a driving shaft and a fixing base fixedly connected to the driving shaft, wherein the driving portion is used to drive the fixing base to rotate via the driving shaft, and the fixing base is used to fixedly accommodate a sample container loaded with a sample; A transport device, used for transporting the sample container to a fixing seat of the sample mixing device; A control device is electrically connected to the sample transport device, the drive unit, and the transport device, and is configured to: Controlling the transport device to transport the sample container transported to the mixing position to the fixing seat of the sample mixing device; Controlling the driving unit to drive the fixing base to move in a manner that its driving speed gradually increases from an initial speed to a preset maximum speed, thereby driving the sample container contained in the fixing base to move, thereby performing a mixing operation on the sample in the sample container in the fixing base at which the speed is gradually increased from the initial speed to the preset maximum speed, wherein the driving unit is first controlled to drive the fixing base to move at a first driving speed for a first preset time period; The driving unit is then controlled to drive the fixing base to move for a second preset time period at a second driving speed different from the first driving speed.

21. A computer-readable storage medium storing executable instructions, configured to cause a processor to execute the executable instructions to implement the sample mixing method according to any one of claims 1 to 13.

Images