Active valve control mechanism for flow channel and microfluidic chip

Abstract

The present invention discloses a flow channel active valve control mechanism and a microfluidic chip. The flow channel active valve control mechanism includes a valve control component, a limiting component and an action component. The valve control component has a valve control rod and a valve control elastic member. The valve control rod is used to open or close the flow channel of the microfluidic chip. The valve control elastic member is connected to the valve control rod to assist in resetting the valve control rod. The limiting component includes a limiting rod and a limiting elastic member. The limiting elastic member is connected to the limiting rod to drive the limiting rod to move. The limiting rod can be driven to move by the limiting elastic member to limit the valve control rod. The action component is used to be installed on the chip support plate of the microfluidic chip. The action component is used to apply an action to the valve control rod to realize the movement of the valve control rod. The action component is also used to apply an action to the limiting rod to realize the movement of the limiting rod. The above-mentioned flow channel active valve control mechanism is miniaturized, simple in structure, and has high reliability of the whole machine.

Description

Technical Field

[0001] The present invention relates to the technical field of biological detection and immune diagnosis, and in particular to a flow channel active valve control mechanism and a microfluidic chip. Background Art

[0002] In clinical analysis, when using a disc-type microfluidic chip loaded with blood samples and multiple reagents, the blood samples or reagents are injected into the reaction chamber through the flow channel in batches under the drive of centrifugal force, and the liquid after a period of reaction flows into the waste liquid chamber through the flow channel in batches. In order to prevent the blood sample or reagent from not staying in the reaction chamber and directly flowing into the waste liquid chamber, it is necessary to set an active valve control mechanism on the flow channel between the reaction chamber and the waste liquid chamber to control the opening and closing of the flow channel. In the prior art solution, a linear motor solution is adopted, and the linear motor is fixed on the chip support plate of the microfluidic chip. The linear motor shaft moves linearly to realize the opening or closing function of the flow channel of the chip. In actual use, the weight of the linear motor is large, which will greatly increase the load of the microfluidic rotary drive motor. The linear motor is large in size, which hinders the miniaturization design of the chip support plate; in addition, the linear motor performs high-speed rotation with the microfluidic chip, and it is necessary to add a conductive slip ring on the chip support plate of the microfluidic chip to power the linear motor, which increases the electrical complexity of the entire microfluidic chip system. This method is increasingly unable to meet the needs of active valve control in practical applications. Summary of the invention

[0003] Based on this, it is necessary to provide a flow channel active valve control mechanism and a microfluidic chip that are conducive to miniaturization of the microfluidic chip, reduce the load of the microfluidic chip, have a simple mechanical structure of the moving parts, and improve the reliability of the entire mechanism.

[0004] A flow channel active valve control mechanism comprises a valve control component, a limiting component and an action component, the valve control component comprises a valve control rod and a valve control elastic component, the valve control rod is used to be movably connected to the chip support plate of the microfluidic chip to open or close the flow channel of the microfluidic chip, and the valve control elastic component is connected to the valve control rod to assist in resetting the valve control rod; the limiting component comprises a limiting rod and a limiting elastic component, the limiting rod is used to be movably connected to the chip support plate of the microfluidic chip, the limiting elastic component is connected to the limiting rod to drive the limiting rod to move, and the limiting rod can be driven to move by the limiting elastic component to limit the valve control rod; the action component is used to be installed on the chip support plate of the microfluidic chip, the action component is used to apply action to the valve control rod to realize the movement of the valve control rod, and the action component is also used to apply action to the limiting rod to realize the movement of the limiting rod.

[0005] In one embodiment, the extension direction of the valve control rod is perpendicular to the extension direction of the limit rod. When the valve control elastic member is in a reset state, the limit elastic member is in a compressed state, and the limit rod abuts against the valve control rod.

[0006] In one embodiment, the action component includes a lifting rod, a lifting seat, a reset lever, a lever elastic member, a lever base and a lifting driver, the lifting rod is connected to the lifting seat, the lifting driver is connected to the lifting seat to drive the lifting seat to move, the lifting rod and the valve control rod are arranged opposite to each other, the reset lever is elastically connected to the lever base through the lever, the reset lever is used to move the limit lever to squeeze the limit elastic member to reset, when the lifting driver drives the lifting seat to move toward the valve control rod, the lifting rod can press the valve control rod to push the valve control rod to move and squeeze the valve control elastic member, when the lifting driver drives the lifting seat to reset and continue to move away from the valve control rod, the lifting seat can squeeze the reset lever to move.

[0007] In one embodiment, the action component further includes a limiting guide rail, the limiting guide rail is connected to the lever base, the limiting guide rail extends parallel to the limiting lever, and the reset lever is slidably connected to the limiting guide rail.

[0008] In one embodiment, the reset lever is in an L-shaped structure, the first side arm of the reset lever extends toward the limit rod and cooperates with the limit rod, the second side arm of the reset lever extends toward the top seat, and the top seat has a slope surface that can cooperate with the second side arm of the reset lever, and when the lifting drive drives the top seat to move away from the valve control rod, the slope surface of the top seat can squeeze the second side arm to push the reset lever to move along the limit guide rail.

[0009] In one embodiment, the action component further includes a rolling element, and the rolling element is rotatably connected to the end of the second side arm, and the slope of the top seat can cooperate with the rolling element.

[0010] In one embodiment, when the lever elastic member is in a reset state, the rolling member contacts and cooperates with the non-slope position of the top seat.

[0011] In one embodiment, the limiting component further includes a matching baffle plate, the matching baffle plate is connected to the limiting rod, and the reset lever can cooperate with the matching baffle plate.

[0012] In one embodiment, the valve-controlled elastic member is a linear spring, and / or the limiting elastic member is a linear spring.

[0013] A microfluidic chip comprises the flow channel active valve control mechanism, wherein the valve control rod of the flow channel active valve control mechanism is movably connected to a chip support plate of the microfluidic chip for opening or closing the flow channel of the microfluidic chip, and the limit rod is movably connected to the chip support plate of the microfluidic chip.

[0014] The above-mentioned channel active valve control mechanism can realize the open and closed states of a specific channel in a microfluidic chip that needs to perform high-speed rotational motion, and the valve control component and the limit component are designed to be separated from the action component, and all electrical components are in the action component, which can make the valve control component and the limit component that rotate with the microfluidic chip miniaturized and lightweight, which is beneficial to the miniaturization of the chip support plate of the microfluidic chip and the reduction of the chip load of the microfluidic chip. In addition, the valve control component and the limit component have only a simple mechanical structure, which can improve the reliability of the entire mechanism.

[0015] When the above-mentioned flow channel active valve control mechanism is in the reset state, the valve control rod is in a natural state under the elastic force of the valve control elastic part, and the valve control rod opens the flow channel of the microfluidic chip. At this time, the limit rod limits and compresses the limit elastic part, and the limit rod abuts against the valve control rod. Due to the obstruction of the valve control rod, the limit rod squeezes the limit elastic part, and the limit elastic part is in a compressed state. At this time, the valve control component and the limit component are in a separated state from the action component, and the valve control component and the limit component can follow the microfluidic chip to complete high-speed rotation. When the flow channel needs to be closed, the lifting driver drives the top seat to move toward the valve control rod to drive the lifting rod to gradually contact and push the valve control rod, and the valve control rod squeezes the valve control elastic member. When the valve control rod is separated from the limit rod, the limit rod moves forward under the elastic force of the limit elastic member. When the limit rod moves to the end of the valve control rod, the limit rod limits the valve control rod, and the valve control rod closes the flow channel. At this time, the lifting driver drives the top seat to reset to drive the lifting rod to reset. Although the valve control rod is no longer driven by the lifting rod, the valve control rod cannot be reset due to the obstruction of the limit rod. The limit rod keeps the valve control rod in the closed state of the flow channel. Since the lifting driver and the lifting rod are separated from the valve control rod, at this time, the valve control component and the limit component can follow the microfluidic chip to complete the high-speed rotation action. When it is necessary to open the flow channel again, the valve control rod is in the reset state, and the limit rod is in the initial position, that is, the limit elastic part is in the compressed state, and the lifting driver drives the top seat to move in the opposite direction away from the valve control rod, and the slope of the top seat will contact the rolling element. When the lifting driver continues to drive the top seat to move in the opposite direction away from the valve control rod, the slope of the top seat will gradually push the rolling element, and the reset lever connected to the rolling element will squeeze the lever elastic part under the limiting action of the limiting guide rail, the reset lever will move the limit lever and squeeze the limit elastic part, and the limit lever will gradually leave the end face of the valve control rod. At this time, the valve control rod will reset under the elastic force of the valve control elastic part to open the flow channel, and the lifting driver drives the top seat to reset, that is, return to the initial position, and the reset lever is reset under the elastic force of the lever elastic part.

[0016] The above-mentioned flow channel active valve control mechanism limits the movement direction of the reset lever by setting a limit guide rail, and the reset lever reciprocates along the limit guide rail to achieve the movement of the limit lever and the reset of itself.

[0017] The above-mentioned active flow channel valve control mechanism is provided with an L-shaped structure of the reset lever and a slope on the top seat. At this time, the lifting lever or the reset lever can be driven by the action of a lifting driver, and one driver can drive two actions, further simplifying the mechanical structure. When the lifting driver drives the top seat to move away from the valve control lever, the slope of the top seat can squeeze the second side arm, and due to the limiting effect of the limit guide rail, the reset lever pushes the reset lever to move along the limit guide rail, and the reset lever drives the limit rod to move.

[0018] The above-mentioned flow channel active valve control mechanism converts the sliding friction between the slope of the top seat and the reset lever into rolling friction by providing a rolling element, thereby reducing the friction force and improving the smoothness of the cooperation between the slope of the top seat and the rolling element.

[0019] The flow channel active valve control mechanism is provided with a matching baffle, and the reset lever can cooperate with the matching baffle. When the reset lever compresses the lever elastic part, the reset lever can directly touch the matching baffle, and the structure is simple. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A schematic diagram of one state of the flow channel active valve control mechanism according to an embodiment of the present invention;

[0021] Figure 2 It is a schematic diagram of another state of the flow channel active valve control mechanism according to one embodiment of the present invention;

[0022] Figure 3 Schematic diagram of another state of the active valve control mechanism of the flow channel according to an embodiment of the present invention.

[0023] Description of Reference Numerals

[0024] 10. Active valve control mechanism of flow channel; 100. Valve control component; 110. Valve control rod; 120. Valve control elastic member; 200. Limit component; 210. Limit rod; 220. Limit elastic member; 230. Matching baffle; 300. Action component; 310. Lifting rod; 320. Top seat; 321. Slope; 330. Reset lever; 331. First side arm; 332. Second side arm; 340. Lever base; 350. Limit guide rail; 360. Rolling member; 20. Chip support seat. DETAILED DESCRIPTION

[0025] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0026] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0027] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0028] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0029] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0030] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

[0031] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those generally understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0032] See also Figure 1 As shown, an embodiment of the present invention provides a flow channel active valve control mechanism 10.

[0033] A flow channel active valve control mechanism 10 includes a valve control component 100 , a limit component 200 and an action component 300 .

[0034] The valve control component 100 has a valve control rod 110 and a valve control elastic member 120. The valve control rod 110 is used to be movably connected to the chip support plate of the microfluidic chip to open or close the flow channel of the microfluidic chip. The valve control elastic member 120 is connected to the valve control rod 110 to assist the valve control rod 110 in resetting.

[0035] The limiting component 200 includes a limiting rod 210 and a limiting elastic member 220. The limiting rod 210 is used to be movably connected to the chip support plate of the microfluidic chip. The limiting elastic member 220 is connected to the limiting rod 210 to drive the limiting rod 210 to move. The limiting rod 210 can be driven to move by the limiting elastic member 220 to limit the valve control rod 110.

[0036] The action component 300 is used to be mounted on the chip support plate of the microfluidic chip. The action component 300 is used to apply an action to the valve control rod 110 to achieve the movement of the valve control rod 110. The action component 300 is also used to apply an action to the limit rod 210 to achieve the movement of the limit rod 210.

[0037] In some embodiments, the extension direction of the valve control rod 110 is perpendicular to the extension direction of the limiting rod 210 . When the valve control elastic member 120 is in the reset state, the limiting elastic member 220 is in the compressed state, and the limiting rod 210 abuts against the valve control rod 110 .

[0038] In some embodiments, the action component 300 includes a lifting rod 310, a lifting seat 320, a reset lever 330, a lever elastic member, a lever base 340 and a lifting driver. The lifting driver is not shown in the drawings.

[0039] See also Figure 1 As shown, the lifting rod 310 is connected to the lifting seat 320. The lifting driver is connected to the lifting seat 320 to drive the lifting seat 320 to move. The lifting rod 310 is arranged opposite to the valve control rod 110, and the reset lever 330 is elastically connected to the lever base 340 through the lever. The reset lever 330 is used to move the limit rod 210 to squeeze the limit elastic member 220 for reset. When the lifting driver drives the lifting seat 320 to move toward the valve control rod 110, the lifting rod 310 can press the valve control rod 110 to push the valve control rod 110 to move and squeeze the valve control elastic member 120. When the lifting driver drives the lifting seat 320 to reset and continue to move away from the valve control rod 110, the lifting seat 320 can squeeze the reset lever 330 to move.

[0040] In some embodiments, see Figure 1 As shown, the action component 300 also includes a limit rail 350. The limit rail 350 is connected to the lever base 340. The limit rail 350 extends parallel to the limit rod 210, and the reset lever 330 is slidably connected to the limit rail 350. The above-mentioned flow channel active valve control mechanism 10 limits the movement direction of the reset lever 330 by setting the limit rail 350, and the reset lever 330 reciprocates along the limit rail 350 to achieve the movement of the limit rod 210 and the reset of the reset lever 330.

[0041] In some embodiments, see Figure 1As shown, the reset lever 330 is in an L-shaped structure. The first side arm 331 of the reset lever 330 extends toward the limiting rod 210 and cooperates with the limiting rod 210. The second side arm 332 of the reset lever 330 extends toward the top seat 320. The top seat 320 has a slope 321 that can cooperate with the second side arm 332 of the reset lever 330. When the lifting driver drives the top seat 320 to move away from the valve control rod 110. The slope 321 of the top seat 320 can squeeze the second side arm 332 to push the reset lever 330 to move along the limiting guide rail 350. The above-mentioned flow channel active valve control mechanism 10 is provided with an L-shaped structure of the reset lever 330 and a slope 321 on the top seat 320. At this time, the lifting rod 310 or the reset lever 330 can be driven by the action of a lifting driver. One driver drives two actions, which further simplifies the mechanical structure. When the lifting driver drives the top seat 320 to move away from the valve control rod 110, the slope 321 of the top seat 320 can squeeze the second side arm 332. Due to the limiting effect of the limiting guide rail 350, the reset lever 330 pushes the reset lever 330 to move along the limiting guide rail 350, and the reset lever 330 drives the limiting rod 210 to move.

[0042] In some embodiments, see Figure 1 As shown, the action component 300 further includes a rolling member 360. The rolling member 360 is rotatably connected to the end of the second side arm 332, and the slope 321 of the top seat 320 can cooperate with the rolling member 360. The above-mentioned flow channel active valve control mechanism 10 converts the sliding friction between the slope 321 of the top seat 320 and the reset lever 330 into rolling friction by providing the rolling member 360, thereby reducing the friction force and improving the smoothness of the cooperation between the slope 321 of the top seat 320 and the rolling member 360.

[0043] In a specific embodiment, the rolling member 360 may be a roller.

[0044] In some embodiments, see Figure 1 As shown, when the lever elastic member is in the reset state, the rolling member 360 is in contact with the non-slope surface 321 of the top seat 320 .

[0045] In some embodiments, the limiting component 200 further includes a matching baffle 230. The matching baffle 230 is connected to the limiting rod 210, and the reset lever 330 can be matched with the matching baffle 230. The above-mentioned flow channel active valve control mechanism 10 is provided with the matching baffle 230, and the reset lever 330 can be matched with the matching baffle 230. When the reset lever 330 compresses the lever elastic member, the reset lever 330 can directly touch the matching baffle 230, and the structure is simple.

[0046] In some embodiments, the valve-controlled elastic member 120 is a linear spring, and / or the limiting elastic member 220 is a linear spring.

[0047] The above-mentioned channel active valve control mechanism 10 can realize the open and closed states of a specific channel in a microfluidic chip that needs to perform high-speed rotational motion, and the valve control component 100 and the limit component 200 are designed to be separated from the action component 300. All electrical components are in the action component 300, which can make the valve control component 100 and the limit component 200 that rotate together with the microfluidic chip miniaturized and lightweight, which is beneficial to the miniaturization of the chip support plate of the microfluidic chip and the reduction of the chip load of the microfluidic chip. In addition, the valve control component 100 and the limit component 200 only have a simple mechanical structure, which can improve the reliability of the entire mechanism.

[0048] When the flow channel active valve control mechanism 10 is in the reset state, please refer to Figure 1 As shown ( Figure 1 , Figure 2 , Figure 3 The double-headed arrow in the figure indicates the direction of movement), the valve control rod 110 is in a natural state under the elastic force of the valve control elastic member 120, and the valve control rod 110 opens the flow channel of the microfluidic chip. At this time, the limit rod 210 limits and compresses the limit elastic member 220, and the limit rod 210 abuts against the valve control rod 110. Due to the obstruction of the valve control rod 110, the limit rod 210 squeezes the limit elastic member 220, and the limit elastic member 220 is in a compressed state. At this time, the valve control component 100 and the limit component 200 are both in a separated state from the action component 300, and the valve control component 100 and the limit component 200 can follow the microfluidic chip to complete a high-speed rotation action.

[0049] When the flow channel needs to be closed, the lifting driver drives the lifting seat 320 to move toward the valve control rod 110 to drive the lifting rod 310 to gradually contact and push the valve control rod 110, and the valve control rod 110 squeezes the valve control elastic member 120. When the valve control rod 110 is separated from the limiting rod 210, the limiting rod 210 moves forward under the elastic force of the limiting elastic member 220. When the forward limiting rod 210 moves to the end of the valve control rod 110, the limiting rod 210 limits the valve control rod 110, and the valve control rod 110 closes the flow channel. Please refer to Figure 2 As shown, at this time, the lifting driver drives the lifting seat 320 to reset to drive the lifting rod 310 to reset. Although the valve control rod 110 is no longer driven by the lifting rod 310, the valve control rod 110 cannot be reset due to the obstruction of the limiting rod 210. The limiting rod 210 keeps the valve control rod 110 in the closed state of the flow channel. Since the lifting driver and the lifting rod 310 are separated from the valve control rod 110, at this time, the valve control component 100 and the limiting component 200 can follow the microfluidic chip to complete the high-speed rotation action.

[0050] When the flow channel needs to be opened again, that is, the valve control rod 110 is in the reset state, and the limit rod 210 is in the initial position, that is, the limit elastic member 220 is in the compressed state, the lifting driver drives the top seat 320 to move away from the valve control rod 110 in the reverse direction, and the slope 321 of the top seat 320 contacts the rolling member 360. When the lifting driver continues to drive the top seat 320 to move away from the valve control rod 110 in the reverse direction, please refer to Figure 3 As shown, the slope 321 of the top seat 320 will gradually push the rolling element 360. The reset lever 330 connected to the rolling element 360 will squeeze the lever elastic member under the limiting action of the limiting guide rail 350. The reset lever 330 will move the limiting rod 210 and squeeze the limiting elastic member 220. The limiting rod 210 gradually leaves the end face of the valve control rod 110. At this time, the valve control rod 110 will be reset under the elastic force of the valve control elastic member 120 to open the flow channel. The lifting driver drives the top seat 320 to reset, that is, return to the initial position. The reset lever 330 is reset under the elastic force of the lever elastic member.

[0051] An embodiment of the present invention further provides a microfluidic chip.

[0052] A microfluidic chip includes the above-mentioned flow channel active valve control mechanism 10. The valve control rod 110 of the flow channel active valve control mechanism 10 is movably connected to the chip support plate of the microfluidic chip to open or close the flow channel of the microfluidic chip, and the limit rod 210 is movably connected to the chip support plate of the microfluidic chip.

[0053] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0054] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A flow channel active valve control mechanism, characterized in that: The invention comprises a valve control component, a limiting component and an action component, wherein the valve control component comprises a valve control rod and a valve control elastic component, wherein the valve control rod is used for being movably connected to the chip support plate of the microfluidic chip so as to open or close the flow channel of the microfluidic chip, and the valve control elastic component is connected to the valve control rod so as to assist in resetting the valve control rod; the limiting component comprises a limiting rod and a limiting elastic component, wherein the limiting rod is used for being movably connected to the chip support plate of the microfluidic chip, and the limiting elastic component is connected to the limiting rod so as to drive the limiting rod to move, and the limiting rod can be driven to move by the limiting elastic component so as to limit the valve control rod; the action component is used for being installed on the chip support plate of the microfluidic chip, and the action component is used for applying action to the valve control rod to realize the movement of the valve control rod, and the action component is also used for The positioning rod applies action to realize the movement of the limit rod, and the action components include a lifting rod, a lifting seat, a reset lever, a lever elastic member, a lever base and a lifting driver. The lifting rod is connected to the lifting seat, and the lifting driver is connected to the lifting seat to drive the lifting seat to move. The lifting rod is arranged opposite to the valve control rod, and the reset lever is movably connected to the lever base through the lever elastic member. The reset lever is used to move the limit rod to squeeze the limit elastic member to reset. When the lifting driver drives the top seat to move toward the valve control rod, the lifting rod can press the valve control rod to push the valve control rod to move and squeeze the valve control elastic member. When the lifting driver drives the top seat to reset and continue to move away from the valve control rod, the top seat can squeeze the reset lever to move.

2. The flow channel active valve control mechanism according to claim 1, characterized in that: The extension direction of the valve control rod is perpendicular to the extension direction of the limit rod. When the valve control elastic member is in a reset state, the limit elastic member is in a compressed state, and the limit rod abuts against the valve control rod.

3. The flow channel active valve control mechanism according to claim 1, characterized in that: The action component also includes a limiting guide rail, which is connected to the lever base. The limiting guide rail extends parallel to the limiting lever, and the reset lever is slidably connected to the limiting guide rail.

4. The flow channel active valve control mechanism according to claim 3, characterized in that: The reset lever is in an L-shaped structure, wherein a first side arm of the reset lever extends toward the limit lever and cooperates with the limit lever, and a second side arm of the reset lever extends toward the top seat, and the top seat has a slope surface that can cooperate with the second side arm of the reset lever. When the lifting drive drives the top seat to move away from the valve control rod, the slope surface of the top seat can squeeze the second side arm to push the reset lever to move along the limit guide rail.

5. The flow channel active valve control mechanism according to claim 4, characterized in that: The action component further comprises a rolling member, and the rolling member is rotatably connected to the end of the second side arm, and the slope surface of the top seat can cooperate with the rolling member.

6. The flow channel active valve control mechanism according to claim 5, characterized in that: When the lever elastic member is in a reset state, the rolling member is in contact with and matched with the non-slope surface position of the top seat.

7. The flow channel active valve control mechanism according to claim 4, characterized in that: The limiting component also includes a matching baffle, which is connected to the limiting rod, and the reset lever can be matched with the matching baffle.

8. The flow channel active valve control mechanism according to any one of claims 1 to 7, characterized in that: The valve-controlled elastic member is a linear spring, and / or the limiting elastic member is a linear spring.

9. A microfluidic chip, characterized in that: It comprises the flow channel active valve control mechanism as described in any one of claims 1 to 8, wherein the valve control rod of the flow channel active valve control mechanism is movably connected to the chip support plate of the microfluidic chip for opening or closing the flow channel of the microfluidic chip, and the limit rod is movably connected to the chip support plate of the microfluidic chip.

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