Slide dyeing machine

Abstract

The present invention discloses a slide-making and staining machine, comprising a machine base and a sample rack, wherein a second mounting groove is provided on the machine base, the sample rack is placed in the second mounting groove and slidably cooperates with the second mounting groove, a second locking member is provided between the sample rack and the second mounting groove, and a plurality of sample placement positions for placing sample bottles are provided on the sample rack. The slide-making and staining machine of the present invention is more convenient to operate during detection, and is more convenient to clean and maintain.

Description

Technical Field

[0001] The invention belongs to the field of medical detection, and in particular relates to a slide making and dyeing machine. Background Art

[0002] The steps of liquid-based cytology pathology examination are divided into four stages: sampling, preparation, staining, observation and diagnosis. For each step of liquid-based cytology pathology examination, the corresponding in vitro diagnostic equipment for liquid-based pathology examination includes sample transfer machine, centrifuge, liquid-based oscillator and preparation and staining machine. Among them, the preparation and staining machine is often used to prepare and stain human cell or bacterial samples before pathological analysis. It uses special reagents to remove interfering components in the specimen, prepare and stain the cells in batches, and make thin cell slices for pathological diagnosis. It is suitable for pathological examination of liquid-based cells such as cervical cells, sputum / alveolar lavage fluid, urine cells, serosal cavity cells, and needle aspiration cells.

[0003] In the process of implementing the present invention, the inventors found that there are at least the following problems in the prior art:

[0004] During the test, it is necessary to take and place the sample (bottle), and even to suck the sample from the sample bottle. However, the sample placement structure design of the existing slide making and staining machine is unreasonable, which makes the operation inconvenient during the test and is not conducive to the cleaning and maintenance of the equipment. Summary of the invention

[0005] The object of the present invention is to provide a slide making and dyeing machine, which is more convenient to operate during detection and is more convenient to clean and maintain.

[0006] The technical solution is as follows:

[0007] The slide making and staining machine comprises a machine base and a sample rack, wherein the machine base is provided with a second mounting groove, the sample rack is placed in the second mounting groove and slidably cooperates with the second mounting groove, a second locking piece is provided between the sample rack and the second mounting groove, and the sample rack is provided with a plurality of sample placement positions for placing sample bottles.

[0008] In one of the embodiments, a magnetic block is provided on the sample rack, and at least the position on the base corresponding to the magnetic block is made of magnetic material; or, a magnetic block is provided on the base, and at least the position on the sample rack corresponding to the magnetic block is made of magnetic material.

[0009] In one embodiment, a second position sensing element is disposed on the second mounting groove, and the second position sensing element faces the sample holder.

[0010] In one embodiment, second lifting ears are provided at both ends of the sample holder.

[0011] In one embodiment, a first positioning portion is provided on the sample placement position, and a second positioning portion is provided on the sample bottle. When the sample bottle is placed at the sample placement position, the first positioning portion corresponds to the second positioning portion.

[0012] In one embodiment, the first positioning portion is a positioning protrusion disposed on the sample placement position, and the second positioning portion is a positioning notch disposed at the bottom of the sample bottle, and the positioning notch is biased toward one side of the sample bottle.

[0013] In one of the embodiments, a shielding member is provided on the base, and when the sample bottle is placed in the sample placement position, the shielding member corresponds to the sample bottle.

[0014] In one embodiment, the shielding member is a plurality of baffles disposed on the base, the plurality of baffles are disposed parallel to each other, bar holes are formed between the plurality of baffles, and the width of the bar holes is smaller than the width of the sample bottle.

[0015] The sample bottle comprises a bottle body having an upper opening, wherein a filter is arranged in the bottle body, and the filter separates the bottle body into a first space and a second space; the side of the upper opening opposite to the first space is a sample placement side, and the side of the upper opening opposite to the second space is a sample extraction side.

[0016] In one embodiment, each of the blocking bars corresponds to the sample placement side, and each of the bar holes corresponds to the sample extraction side.

[0017] In one embodiment, the bottle body includes an inner bottle and an outer bottle, the inner bottle is placed in the outer bottle and the inner bottle is located on one side of the outer bottle, the first space is formed in the inner bottle, the second space is formed between the inner bottle and the outer bottle, and the filter is arranged on the inner bottle.

[0018] In one embodiment, the filter is disposed at the bottom of the inner bottle and is located on the opposite side of the second space.

[0019] In one embodiment, the bottom of the inner bottle is lower on a side close to the second space and higher on a side away from the second space, forming an inclined second bottom. A first bottom is formed at the bottom of the outer bottle. The first bottom and the second bottom have the same inclination direction. A lower opening is provided on the second bottom, and the filter is provided at the lower opening.

[0020] In one of the embodiments, a first anti-rebound protrusion is provided on the inner wall of the outer bottle.

[0021] In one of the embodiments, a tube removal piece is provided on the machine base, the tube removal piece is located beside the second mounting groove, and a tube removal notch is provided on the tube removal piece.

[0022] In one of the embodiments, a recovery port is provided on the upper surface of the machine base, and the recovery port is located below the tube-removing sheet. A recovery box is provided on the machine base, and the recovery box is located below the recovery port.

[0023] In one of the embodiments, a third mounting groove is provided on the machine base, and the recycling box is placed in the third mounting groove and slidably cooperates with the third mounting groove.

[0024] In one embodiment, there are at least two sample racks disposed on the second mounting slot.

[0025] The technical solution provided by the present invention has the following advantages and effects:

[0026] The slide making and staining machine described in the present invention is provided with a second mounting groove on its base, and the sample rack is placed in the second mounting groove and slidably cooperates with the second mounting groove. When in use, the sample rack can be pulled out of the second mounting groove by pulling, or the sample rack can be pushed into the second mounting groove, so as to perform operations such as batch loading of samples and maintenance of the sample rack, which is very convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The accompanying drawings herein show specific examples of the technical solutions described in the present invention, and together with the specific implementation methods, constitute a part of the specification, and are used to explain the technical solutions, principles and effects of the present invention.

[0028] Unless otherwise specified or defined, the same reference numerals in different drawings represent the same or similar technical features, and the same or similar technical features may also be represented by different reference numerals.

[0029] Figure 1 This is an overall structural diagram of the slide making and dyeing machine in an embodiment of the present invention;

[0030] Figure 2 is a side view of the pipe rack installation structure in an embodiment of the present invention;

[0031] Figure 3 is a transverse cross-sectional view of the pipe rack installation structure in an embodiment of the present invention;

[0032] Figure 4 is a longitudinal cross-sectional view of the pipe rack installation structure in an embodiment of the present invention;

[0033] Figure 5 is a top view of the pipe rack installation structure in an embodiment of the present invention;

[0034] Figure 6 is a top view of the pipe rack installation structure in an embodiment of the present invention;

[0035] Figure 7 is a longitudinal cross-sectional view of the sample rack in an embodiment of the present invention;

[0036] Figure 8 is a cross-sectional view of the sample rack and the sample bottle in an embodiment of the present invention;

[0037] Fig. 9 is a cross-sectional view of the sample rack, sample bottle and pipette in an embodiment of the present invention;

[0038] Fig.10 is a cross-sectional view of the sample bottle in an embodiment of the present invention;

[0039] Fig.11 is an exploded view of the sample bottle in an embodiment of the present invention;

[0040] Fig.12 is a structural diagram of the outer bottle in an embodiment of the present invention;

[0041] Fig.13 is a structural diagram of the inner bottle in an embodiment of the present invention;

[0042] Fig.14 is a structural diagram of the recycling box in an embodiment of the present invention;

[0043] Description of reference numerals:

[0044] 10. base, 11. rack, 111. translation bracket, 112. mechanical arm, 12. first mounting slot, 121. longitudinal slide slot, 13. second mounting slot, 14. third mounting slot, 15. recycling box, 151. handle, 152. recycling chamber, 16. recycling port,

[0045] 20. pipe rack, 201. first positioning hole, 202. guide protrusion, 21. first locking member, 211. introduction slope, 22. straw placement position, 23. first position sensor element, 24. first lifting ear, 251. bottom plate, 252. connecting plate, 253. top plate,

[0046] 30. Sample rack, 301. Sample placement position, 302. Magnetic block, 303. Second position sensing element, 31. Second lifting ear, 32. First positioning portion,

[0047] 40. Sample bottle, 41. Outer bottle, 411. First anti-reflection convex, 412. First oblique bottom, 413. External thread, 42. Inner bottle, 421. Filter, 422. Second anti-reflection convex, 423. Second oblique bottom, 431. First space, 432. Second space, 441. Sample placement side, 442. Sample extraction side, 45. Second positioning portion, 46. Bottle cap, 461. Inner groove,

[0048] 71, dye rack, 711, dye placement, 72, slide preparation and staining plate, 721, slide placement,

[0049] 81, stop bar, 82, bar hole, 83, detached tube piece, 831, detached tube missing,

[0050] 93. Pipette tip, 94. Liquid bottle, 95. Waste liquid tank, 96. Pipette. DETAILED DESCRIPTION

[0051] In order to facilitate the understanding of the present invention, specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.

[0052] Unless otherwise specified or defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art. In the context of the actual scenario of the technical solution of the present invention, all technical and scientific terms used herein may also have the meaning corresponding to the purpose of implementing the technical solution of the present invention.

[0053] Unless otherwise specified or defined, the "first, second..." used in this article is merely used to distinguish names and does not represent a specific quantity or order.

[0054] Unless specifically stated or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0055] It should be noted that when a component is considered to be "fixed to" another component, it can be directly fixed to the other component or there can be a central component; when an component is considered to be "connected to" another component, it can be directly connected to the other component or there can be a central component at the same time; when an component is considered to be "installed on" another component, it can be directly installed on the other component or there can be a central component at the same time. When an component is considered to be "set on" another component, it can be directly set on the other component or there can be a central component at the same time.

[0056] Unless otherwise specified or defined, the “said” and “the” used in this document refer to the technical features or technical contents mentioned or described before the corresponding position, and the technical features or technical contents may be the same as or similar to the technical features or technical contents mentioned therein.

[0057] Undoubtedly, technical contents or technical features that are contrary to the purpose of the present invention or are obviously contradictory should be excluded.

[0058] like Figures 1 to 14As shown, the slide staining machine includes a base 10, a frame 11 is provided on the base 10, a translation support 111 is provided on the frame 11, a mechanical arm 112 is provided on the translation support 111, and a suction head 93 that can move up and down is installed on the mechanical arm 112. A dye rack 71, a tube rack 20, a slide staining plate 72 and two sample racks 30 are provided on the base 10, a plurality of sample placement positions 301 are provided on the sample rack 30, a plurality of dye placement positions 711 are provided on the dye rack 71, and a plurality of glass slide placement positions 721 are provided on the slide staining plate 72; the suction head 93 can move up and down, left and right relative to the frame 11, and the suction head 93 is directed toward the tube rack 20, the sample rack 30, the dye rack 71 or the slide staining plate 72.

[0059] The tube rack 20 and the sample rack 30 both adopt a pull-out structure: a first mounting groove 12 , a second mounting groove 13 and a third mounting groove 14 are provided on the machine base 10 .

[0060] Please focus on Figures 2 to 5 The pipe rack 20 is installed at the first mounting groove 12 and slides with the first mounting groove 12. The pipe rack 20 can be movably pulled out relative to the first mounting groove 12. A first locking piece 21 is provided between the pipe rack 20 and the first mounting groove 12. A plurality of perforations are provided on the pipe rack 20 to form a plurality of straw placement positions 22. The pipe rack 20 is installed in the first mounting groove 12 by sliding. When in use, the pipe rack 20 can be pulled out of the first mounting groove 12 by pulling, or pushed into the first mounting groove 12. The pipe rack 20 can be easily pulled out to facilitate the placement and removal of the straw 96, or to perform maintenance, cleaning and other operations. It is very convenient to use.

[0061] In this embodiment, an elastic member (not shown in the figure) is provided below the first locking member 21, the outer side height of the first locking member 21 is lower than the inner side height, and an inclined introduction slope 211 is formed on the upper part of the first locking member 21. The first locking member 21 is located at the outer end of the first mounting groove 12 and corresponds to the outer end of the pipe rack 20. A first positioning hole 201 corresponding to the first locking member 21 is provided at the bottom of the pipe rack 20. When the pipe rack 20 slides in, the pipe rack 20 can slide in along the introduction slope 211 and lock the outer end of the pipe rack 20 through the first locking member 21, or it can be locked at the first positioning hole 201 of the pipe rack 20 through the first locking member 21.

[0062] A first position sensor 23 is provided on the first mounting groove 12, and the first position sensor 23 faces the pipe rack 20. The sliding position of the pipe rack 20 can be sensed by the first position sensor 23, and an alarm is given when the position of the pipe rack 20 is not slid into place. The first position sensor 23 can be an optical sensor, a magnetic sensor, or other types of sensor.

[0063] A first lifting ear 24 is provided at both ends of the pipe rack 20, and the first lifting ear 24 is higher than the height of the two end surfaces of the first mounting groove 12. The pipe rack 20 can be pushed, pulled, moved, etc. through the first lifting ear 24, thereby improving the convenience of operation. To avoid interference and affecting the operation, the first lifting ear 24 is higher than the height of the two end surfaces of the first mounting groove 12.

[0064] Please focus on Figure 3 The pipe rack 20 includes a bottom plate 251, a connecting plate 252, and a top plate 253. The bottom plate 251 and the top plate 253 are connected by the connecting plate 252. A plurality of perforations are provided on the top plate 253 to form a plurality of straw placement positions 22. The width of the bottom plate 251 is greater than the width of the top plate 253, and guide protrusions 202 are formed on both sides of the bottom plate 251. A longitudinal slide groove 121 is provided on both sides of the first installation groove 12. The guide protrusion 202 is inserted into the slide groove and slidably cooperates with the slide groove. The bottom plate 251 and the top plate 253 are connected by the connecting plate 252, and the guide protrusions 202 can be formed on both sides of the bottom plate 251. The structure is simple and easy to install.

[0065] Please focus on Figures 6 to 13 There are two sample racks 30, and the two sample racks 30 are placed in the second mounting groove 13 and slide with the second mounting groove 13. The second mounting groove 13 is provided on the base 10 of the slide making and staining machine described in this embodiment. The sample rack 30 is placed in the second mounting groove 13 and slides with the second mounting groove 13. When in use, the sample rack 30 can be pulled out of the second mounting groove 13 by pulling, or the sample rack 30 can be pushed into the second mounting groove 13, so as to perform operations such as batch loading of samples, maintenance and cleaning of the sample rack 30, which is very convenient to use. There are two sample racks 30, and the user can use the two sample racks 30 simultaneously or staggered according to the detection requirements to improve work efficiency.

[0066] A second locking member is provided between the sample rack 30 and the second mounting groove 13. In this embodiment, a magnetic block 302 is provided on the machine base 10. The position on the sample rack 30 corresponding to the magnetic block 302 is made of magnetic material. It can be understood that the magnetic material here can be local, that is, a magnetic block or an iron block is installed here, or the entire sample rack 30 can be processed with iron material. The magnetic block 302 forms a second locking member. When the sample rack 30 slides into place, the position of the sample rack 30 is locked by the magnetic block 302 to prevent the sample rack 30 from falling out; a second position sensor element 303 is provided on the second mounting groove 13, and the second position sensor element 303 faces the sample rack 30. The sliding position of the sample rack 30 can be sensed by the second position sensor element 303, and an alarm is issued when the position of the sample rack 30 does not slide into place. The second position sensor element 303 can be an optical sensor element, a magnetic sensor element, or other types of sensor elements. There are two sample racks 30, which can be replaced alternately as needed to avoid affecting sample detection due to sample replacement, thereby improving detection efficiency.

[0067] A second lifting ear 31 is provided at both ends of the sample rack 30. The sample rack 30 can be pushed, pulled, moved, etc. through the second lifting ear 31, thereby improving the convenience of operation. To avoid interference and facilitate operation, the first lifting ear 24 is higher than the table height at both ends of the first mounting groove 12.

[0068] A first positioning portion 32 is provided on the sample placement position 301, and a second positioning portion 45 is provided on the sample bottle 40. When the sample bottle 40 is placed in the sample placement position 301, the first positioning portion 32 corresponds to the second positioning portion 45. In this embodiment, the first positioning portion 32 is a positioning protrusion provided on the sample placement position 301, and the second positioning portion 45 is a positioning notch provided at the bottom of the sample bottle 40, and the positioning notch is biased toward one side of the sample bottle 40. If the sample bottle 40 is placed in the opposite direction, or the sample bottle 40 is rotated by a certain angle, the sample bottle 40 cannot be placed. By setting the first positioning portion 32 and the second positioning portion 45, the direction of the sample bottle 40 can be kept consistent, ensuring that the pipette 96 can be correctly inserted into the sample extraction side 442 to complete the enrichment and transfer operations of the sample.

[0069] The structure of the sample bottle 40 used in this embodiment is mainly combined with Figures 10 to 13As shown, the sample bottle 40 includes an inner bottle 42 and an outer bottle 41. The inner bottle 42 is placed in the outer bottle 41 and is located on one side of the outer bottle 41. A first space 431 is formed in the inner bottle 42, and a second space 432 is formed between the inner bottle 42 and the outer bottle 41. The filter 421 is arranged at the bottom of the inner bottle 42 and is located on the opposite side of the second space 432. The bottom of the inner bottle 42 is low on the side close to the second space 432 and high on the side away from the second space 432, forming an inclined second inclined bottom 423. A first inclined bottom 412 is formed at the bottom of the outer bottle 41. The first inclined bottom 412 and the second inclined bottom 423 have the same inclination direction. A lower opening is arranged on the second inclined bottom 423, and the filter 421 is arranged at the lower opening.

[0070] The inner bottle 42 and the outer bottle 41 both have upper openings, and an outer thread 413 is provided at the edge of the upper opening of the outer bottle 41. The inner thread of the bottle cap 46 matches the outer thread 413 and covers the upper opening of the outer bottle 41. The radial inner side of the upper surface of the bottle cap 46 is partially concave to form an inner groove 461, which can effectively prevent the straw 96 from tilting or slipping when inserted. One side of the upper opening of the inner bottle 42 is the sample placement side 441, which corresponds to the first space 431; the position opposite to the second space 432 between the inner bottle 42 and the outer bottle 41 is the sample extraction side 442.

[0071] The sample bottle 40 described in this embodiment adopts a partitioned structure, which has a first space 431 and a second space 432. The side of the upper opening of the sample bottle 40 opposite to the first space 431 forms a sample placement side 441, and the side of the upper opening opposite to the second space 432 forms a sample extraction side 442. When performing a test, the sample is placed from the sample placement side 441 of the sample bottle 40, and the pipette 96 is inserted from the sample extraction side 442. The reagent in the sample bottle 40 is repeatedly aspirated through the pipette 96 to separate the target cells from the sample, and then the sample is extracted with the pipette 96 to enrich and transfer the sample. This structure can conveniently realize the transfer and enrichment of the sample, and the structure is relatively simple and the operation is more convenient.

[0072] The filter 421 is located on the opposite side of the second space 432. When the liquid is repeatedly sucked by the pipette 96, the structure can play a buffering and balancing role, avoiding the liquid flow under the action of the pipette 96. The strong impact on the filter 421 locally affects the extraction of the sample target cells and reduces the generation of impurities. After the sample is repeatedly rinsed by the liquid flow, the target cells in the sample are enriched to the bottom of the outer bottle 41 through the first inclined bottom 412, reducing the amount of sample required and reducing the cost of using samples and consumables.

[0073] A first anti-reflection convexity 411 is provided on the inner wall of the outer bottle 41, and a second anti-reflection convexity 422 is provided on the outer wall of the inner bottle 42. The first anti-reflection convexity 411 is close to one side of the second space 432. The inner bottle 42 can only be placed in a set direction. If it is deflected when placed, the inner bottle 42 will not be able to be placed in the outer bottle 41. This structure can ensure the position of the inner bottle 42 in the outer bottle 41. The sample bottle 40 adopts a double-layer structure. When in use, the outer bottle 41 can be used alone, or the inner bottle 42 and the outer bottle 41 can be used together according to the detection purpose and the instrument used.

[0074] Please focus on Figure 1 , Figure 6 , Figure 8 and Fig. 9 A plurality of baffles 81 are provided on the base 10 to form a shielding member. When the sample bottle 40 is placed in the sample placement position 301, the shielding member corresponds to the sample bottle 40. The plurality of baffles 81 are arranged in parallel with each other, and bar holes 82 are formed between the plurality of baffles 81. When the suction head 93 moves upward, the suction tube 96 can be prevented from driving the sample bottle 40 upward. The width of the bar hole 82 is smaller than the width of the sample bottle 40, so that the sample bottle 40 can be prevented from falling out of the bar hole 82, and the suction tube 96 can be prevented from being inserted from the sample placement side 441 to cause sample contamination.

[0075] The base 10 is provided with a tube removal piece 83, which is located beside the second mounting groove 13, and a tube removal notch 831 is provided on the tube removal piece 83. A recovery port 16 is provided on the upper surface of the base 10, which is located below the tube removal piece 83. The base 10 is provided with a third mounting groove 14, a recovery box 15 is placed in the third mounting groove 14 and slidably cooperates with the third mounting groove 14, the recovery box 15 is located below the recovery port 16, a recovery cavity 152 is provided in the recovery box 15, and a handle 151 is provided on the outside of the recovery box 15. After the straw 96 is used, the robotic arm 112 drives the suction head 93 to move to the tube removal gap 831 and lifts up the suction head 93. The straw 96 falls off the suction head 93 and falls into the recycling box 15. When the number of suction heads 93 in the recycling box 15 reaches a certain number, the recycling box 15 can be pulled out of the third installation slot 14, and the straws 96 in the recycling box 15 can be discarded and recycled. After the recycling is completed, the recycling box 15 can be slid into the third installation slot 14.

[0076] A waste liquid tank 95 and a liquid bottle 94 are also provided on the machine base 10, and a pump body (not shown in the figure) is provided on the frame 11, and the pump body is connected to the suction head 93 and the liquid bottle 94 through a connecting pipe. The pump body can control the pressure of the suction tube 96 at the end of the suction head 93 so as to suck the reagent or sample, and the anhydrous ethanol in the liquid bottle 94 can also be used to clean and empty the entire pipeline.

[0077] The operation method of the slide dyeing machine described in this embodiment is:

[0078] 1. Preparation

[0079] The dyeing machine is powered on;

[0080] Open the bottle cap 46 of the sample bottle 40, and place the inner bottle 42 into the outer bottle 41. When placing the inner bottle 42, pay attention to the matching direction between the first anti-reflection convex 411 and the inner bottle 42. If the direction is misaligned, the inner bottle 42 cannot be placed in; put the cell preservation solution in the sample bottle 40 in advance, place the test sample on the sample placement side 441 of the sample bottle 40, and then cover the bottle cap 46; after collecting multiple samples through multiple sample bottles 40, place the multiple sample bottles 40 in the sample placement positions 301 of the sample rack 30 respectively; slide the sample rack 30 with multiple samples into the second installation groove 13, and when the sample groove slides into place, it is magnetically locked by the magnetic block 302. If the sample rack 30 does not slide into place, it can be displayed or prompted externally after sensing by the second position sensor element 303; after the sample rack 30 slides into place, the sample placement side 441 is blocked by the blocking bar 81 of the sample rack 30, and the sample extraction side 442 is located between the two blocking bars 81;

[0081] Insert multiple straws 96 into the straw placement positions 22 on the pipe rack 20 in sequence, and slide the pipe rack 20 with the straws 96 inserted into the first installation groove 12; if the pipe rack 20 slides into place, the pipe rack 20 is locked by the first locking member 21, and the pipe rack 20 will not fall out easily; if the pipe rack 20 does not slide into place, the first position sensor 23 can sense and display or prompt externally;

[0082] 2. Extraction straw 96

[0083] The robot arm 112 moves, the suction head 93 moves down and extracts the suction tube 96 on the tube rack 20;

[0084] 3. Emptying and cleaning

[0085] Pour anhydrous alcohol into the liquid bottle 94, start the pump body, and transfer the anhydrous alcohol in the liquid bottle 94 to the suction head 93 through the hose to clean and empty the pipeline and the suction head 93. The used anhydrous alcohol is discharged into the waste liquid tank 95 for temporary storage;

[0086] 4. Enrichment

[0087] Under the action of the pump body, the suction head 93 repeatedly sucks the liquid, and the liquid forms a liquid flow on both sides of the filter 421. When the suction head 93 sucks the liquid, the liquid flow drives the sample cell solution on the sample placement side 441 to pass through the filter 421 to filter out the target cells and enter the sample extraction side 442. When the suction head 93 discharges the liquid, the liquid flow flushes the sample impurities blocked on the filter 421. The sample cell solution on the sample placement side 441 is repeatedly filtered through repeated suction by the suction head 93, and finally a sufficient number of target cells are enriched to the sample extraction side 442.

[0088] 5. Transfer

[0089] Under the action of the pump, the suction head 93 sucks the reagent with the sample into the suction tube 96, and the mechanical arm 112 moves to transfer the sample and drop it onto the glass slide on the preparation and staining plate 72;

[0090] 6. Staining and slide making

[0091] The mechanical arm 112 moves, the suction head 93 moves down and extracts the dye from the dye rack 71, and drips the dye onto the glass slide on the slide preparation and dyeing plate 72, and leaves it to stand;

[0092] 7. Remove the slide for observation and diagnosis.

[0093] The purpose of the above embodiments is to exemplarily reproduce and deduce the technical solution of the present invention, and to fully describe the technical solution, purpose and effect of the present invention. Its purpose is to make the public understand the disclosed content of the present invention more thoroughly and comprehensively, and it does not limit the scope of protection of the present invention.

[0094] The above embodiments are not exhaustive enumerations of the present invention, and there may be multiple other implementations not listed. Any replacement and improvement made without violating the concept of the present invention shall fall within the protection scope of the present invention.

Claims

1. A film making and dyeing machine, characterized in that: The machine base comprises a machine base and a sample rack, wherein a second mounting groove is provided on the machine base, the sample rack is placed in the second mounting groove and slidably cooperates with the second mounting groove, a second locking member is provided between the sample rack and the second mounting groove, and a plurality of sample placement positions for placing sample bottles are provided on the sample rack; A shielding member is provided on the machine base, and when the sample bottle is placed in the sample placement position, the shielding member corresponds to the sample bottle; The shielding member is a plurality of baffles arranged on the base, the plurality of baffles are arranged parallel to each other, bar holes are formed between the plurality of baffles, the width of the bar holes is smaller than the width of the sample bottle, and the bar holes are in the shape of long strips; The sample bottle comprises a bottle body, the bottle body has an upper opening, a filter screen is arranged in the bottle body, and the filter screen separates the bottle body into a first space and a second space; the side of the upper opening opposite to the first space is a sample placement side, and the side of the upper opening opposite to the second space is a sample extraction side; Each of the baffles corresponds to the sample placement side, and each of the bar holes corresponds to the sample extraction side.

2. The film making and dyeing machine according to claim 1, characterized in that: A magnetic block is provided on the sample rack, and at least the position on the base corresponding to the magnetic block is made of magnetic material; or, a magnetic block is provided on the base, and at least the position on the sample rack corresponding to the magnetic block is made of magnetic material.

3. The film making and dyeing machine according to claim 1, characterized in that: A second position sensing element is disposed on the second mounting groove and faces the sample rack.

4. The film making and dyeing machine according to claim 1, characterized in that: Second lifting ears are provided at both ends of the sample rack.

5. The sheet making and dyeing machine according to claim 1, characterized in that: A first positioning portion is provided on the sample placement position, and a second positioning portion is provided on the sample bottle. When the sample bottle is placed at the sample placement position, the first positioning portion corresponds to the second positioning portion.

6. The sheet making and dyeing machine as claimed in claim 5, characterized in that: The first positioning portion is a positioning protrusion disposed on the sample placement position, and the second positioning portion is a positioning notch disposed at the bottom of the sample bottle, and the positioning notch is biased toward one side of the sample bottle.

7. The sheet making and dyeing machine according to claim 1, characterized in that: The bottle body includes an inner bottle and an outer bottle, the inner bottle is placed in the outer bottle and is located on one side of the outer bottle, the first space is formed in the inner bottle, the second space is formed between the inner bottle and the outer bottle, and the filter is arranged on the inner bottle.

8. The sheet making and dyeing machine as claimed in claim 7, characterized in that: The filter is arranged at the bottom of the inner bottle and is located at the opposite side of the second space.

9. The sample bottle according to claim 8, characterized in that: The bottom of the inner bottle is lower on the side close to the second space and higher on the side away from the second space, forming an inclined second bottom. A first bottom is formed at the bottom of the outer bottle. The first bottom and the second bottom have the same inclination direction. A lower opening is provided on the second bottom, and the filter is provided at the lower opening.

10. The slide dyeing machine according to claim 7, characterized in that: A first anti-reverse protrusion is provided on the inner wall of the outer bottle.

11. The slide dyeing machine according to any one of claims 1 to 6, characterized in that: A tube-removing piece is provided on the machine base, and the tube-removing piece is located beside the second mounting groove, and a tube-removing notch is provided on the tube-removing piece.

12. The sheet making and dyeing machine according to claim 11, characterized in that: A recovery port is provided on the upper surface of the machine base, and the recovery port is located below the tube-removing sheet. A recovery box is provided on the machine base, and the recovery box is located below the recovery port.

13. The sheet making and dyeing machine according to claim 12, characterized in that: A third mounting groove is arranged on the machine base, and the recovery box is placed in the third mounting groove and slidably matched with the third mounting groove.

14. The slide dyeing machine according to any one of claims 1 to 6, characterized in that: There are at least two sample racks arranged on the second mounting groove.

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