Reaction cup mixing device
By designing a reaction cup mixing device including incubation plate, mixing rotating plate and friction strip, the problem of unevenness caused by material settlement in the reaction detection sample solution is solved, and the uniform mixing of liquid and the improvement of reaction detection effect is achieved. .
Patent Information
- Application Number
- CN202110698128.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-06-23
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2041-06-23
AI Technical Summary
In the prior art, substances such as reaction beads and fluorescent markers in the reaction detection sample solution will settle when the reaction is stationary for a long time during the reaction, resulting in uneven reaction detection sample solution and affecting the detection effect.
A reaction cup mixing device is designed, including a rack, incubation plate, mixing rotating plate, mixing rotating mechanism and friction strips. The mixing and rotating mechanism drives the mixing and rotating disc to rotate, and the friction strips come into contact with the reaction cup in the incubation plate, and drives the reaction cup to rotate, thereby achieving uniform mixing of the liquid.
Through this device, the liquid in the reaction cup can achieve relatively uniform mixing, which improves the accuracy and reliability of reaction detection.
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Figure CN113274922B_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of medical devices, and in particular to a reaction cup mixing device. Background Art
[0002] In the prior art, substances such as reaction magnetic beads and fluorescent markers in the reaction detection sample solution will settle if left stationary for a long time during the reaction process, resulting in uneven reaction detection sample solution, which in turn affects the detection effect. In order to ensure the uniformity of the solution and prevent sedimentation, mixing is required. Summary of the invention
[0003] The purpose of the present application is to provide a reaction cup mixing device, which can make the mixing effect more uniform.
[0004] The embodiment of the present application is implemented as follows:
[0005] In the first aspect, the present application provides a reaction cup mixing device, comprising: a frame, an incubation disk, a mixing rotating disk, a mixing rotating mechanism and at least one friction strip, wherein the incubation disk is arranged on the frame, and the incubation disk is provided with at least one mounting groove for mounting the reaction cup; the mixing rotating disk is arranged on the frame and is located above the incubation disk; the mixing rotating mechanism is arranged on the frame and is transmission-connected to the mixing rotating disk for driving the mixing rotating disk to rotate; the friction strip is fixed on the mixing rotating disk, and is used to contact the reaction cup to drive the reaction cup to rotate.
[0006] In one embodiment, there are multiple mounting grooves, which are divided into a first group of grooves and a second group of grooves, the mounting grooves in the first group of grooves are distributed in a circular array around the axis of the incubation tray, the mounting grooves in the second group of grooves are distributed in a circular array around the axis of the incubation tray, and the second group of grooves are located outside the first group of grooves; accordingly, there are multiple friction strips, which are divided into a first group of strips and a second group of strips, the second group of strips are located outside the first group of strips, the friction strips in the first group of strips are used to drive the reaction cups in the first group of grooves to rotate, and the friction strips in the second group of strips are used to drive the reaction cups in the second group of grooves to rotate.
[0007] In one embodiment, the mixing rotating disk and the incubation disk are coaxially arranged.
[0008] In one embodiment, there are multiple friction strips in the first group of strips, and the friction strips in the first group of strips are distributed in a circular array around the axis of the mixing rotating disk; there are multiple friction strips in the second group of strips, and the friction strips in the second group of strips are distributed in a circular array around the axis of the mixing rotating disk.
[0009] In one embodiment, the circumferential length of the friction strip is greater than the diameter of the mounting groove.
[0010] In one embodiment, the frame includes: an insulation chamber and an upper cover arranged on the top of the insulation chamber, the incubation plate and the mixing rotating plate are both arranged in the insulation chamber; a first through hole is provided on the upper cover; the mixing rotating mechanism includes: a first rotating driving member and a first transmission mechanism, the first rotating driving member has a first main shaft; the first rotating driving member is arranged on the upper cover, and the first main shaft passes through the first through hole and extends into the insulation chamber; the first transmission mechanism is arranged in the insulation chamber, and the first main shaft and the mixing rotating plate are connected by transmission.
[0011] In one embodiment, the reaction cup mixing device further includes: an incubation rotating mechanism, which is disposed on the frame and is drivingly connected to the incubation tray for driving the incubation tray to rotate.
[0012] In one embodiment, the frame further comprises: a bottom plate disposed at the bottom of the heat preservation bin, the bottom plate is provided with a second through hole, and the heat preservation bin is provided with a third through hole.
[0013] The incubation rotating mechanism includes: a central axis, a second rotating drive member, a second transmission mechanism and a support frame, the central axis is connected to the incubation tray after passing through the second through hole and the third through hole; the second rotating drive member has a second main shaft; the second transmission mechanism is arranged on the bottom plate, and the second main shaft and the incubation tray are connected by transmission; the support frame is respectively connected to the second rotating drive member and the frame; wherein the second rotating drive member, the support frame and the first rotating drive member are all arranged on the outside of the insulation chamber, and are all arranged on the other side of the bottom plate relative to the incubation tray.
[0014] In one embodiment, a fourth through hole is disposed on the mixing rotating disk, and the reaction cup mixing device further comprises: at least one first bearing, wherein the first bearing is disposed in the fourth through hole and sleeved on the central axis.
[0015] In one embodiment, the reaction cup mixing device further includes: a counting mechanism, the counting mechanism includes a code disk and a counting optical coupler, the counting optical coupler is arranged on a frame, and the code disk is drivingly connected to the incubation disk.
[0016] In one embodiment, the reaction cup mixing device further includes: a zero position mechanism, the zero position mechanism includes a zero position baffle and a zero position optical coupler, the zero position optical coupler is arranged on the frame, and the zero position baffle is arranged on the code disk.
[0017] The beneficial effects of this application compared with the prior art are:
[0018] The present application drives the mixing rotating disk to rotate through a mixing rotating mechanism, and the friction strip can contact the reaction cup installed in the incubation disk to drive the reaction cup to rotate, so that the liquid in the reaction cup is mixed, and the mixing effect is relatively uniform. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.
[0020] Figure 1 This is a schematic diagram of the structure of a reaction cup mixing device shown in one embodiment of the present application.
[0021] Figure 2 This is a partial structural schematic diagram of a reaction cup mixing device shown in one embodiment of the present application.
[0022] Figure 3 This is a schematic diagram of the structure of an incubation disk and a mixing rotating disk in a reaction cup mixing device shown in one embodiment of the present application.
[0023] Figure 4 A side view of a reaction cup mixing device shown in one embodiment of the present application.
[0024] Figure 5 An exploded view of a reaction cup mixing device shown in one embodiment of the present application.
[0025] Figure 6 An exploded view of a reaction cup mixing device shown in one embodiment of the present application.
[0026] Figure 7 This is a bottom view of a reaction cup mixing device shown in one embodiment of the present application.
[0027] Figure 8 A cross-sectional view of a reaction cup mixing device shown in one embodiment of the present application.
[0028] Icons: 10-cup mixing device; 100-frame; 110-insulation chamber; 111-third perforation; 120-upper cover; 121-first perforation; 123-functional opening; 130-bottom plate; 131-second perforation; 140-support foot; 150-connecting frame; 160-sealing ring; 170-main control panel; 200-incubation tray; 210-installation slot; 211-first group of slots; 21 2-second set of grooves; 220-annular groove; 230-identifier; 201-incubation outer ring; 202-incubation inner ring; 203-heating film; 204-temperature control switch; 205-pressing plate; 206-temperature sensor; 300-mixing rotating disk; 310-fourth perforation; 311-first bearing seat; 312-first bearing; 400-friction strip; 401-first set of strips; 402-second set Strip; 410-rubber strip; 411-arc-shaped protrusion; 420-fixed seat; 500-mixing rotation mechanism; 510-first rotating drive member; 511-first main shaft; 512-dust cover; 520-first transmission mechanism; 521-driving gear; 522-driven gear; 600-incubation rotation mechanism; 610-central axis; 611-second bearing insulation member; 612-second bearing seat; 613-second bearing; 620-second rotating drive member; 621-second main shaft; 630-second transmission mechanism; 631-synchronous belt; 632-driving pulley; 633-driven pulley; 640-support frame; 700-counting mechanism; 710-code disk; 720-counting optical coupler; 800-zero position mechanism; 810-zero position baffle; 820-zero position optical coupler; 90-reaction cup; 91-friction member. DETAILED DESCRIPTION
[0029] The terms “first”, “second”, “third”, etc. are only used for distinguishing descriptions and do not indicate the order of arrangement, nor can they be understood as indicating or implying relative importance.
[0030] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components are required to be absolutely horizontal or overhanging, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.
[0031] In the description of the present application, it should be noted that the terms "inside", "outside", "left", "right", "up", "down", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, or are directions or positional relationships in which the products of the present application are usually placed when in use. They are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present application.
[0032] In the description of this application, unless otherwise clearly specified and limited, the terms "set", "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the internal connection of two elements.
[0033] The technical solution of the present application will be described clearly and completely below in conjunction with the accompanying drawings.
[0034] Please refer to Figure 1 , which is a schematic diagram of the structure of a reaction cup mixing device 10 shown in an embodiment of the present application. A reaction cup mixing device 10 includes: a frame 100 and a mixing rotation mechanism 500, the mixing rotation mechanism 500 is arranged on the frame 100, the frame 100 includes: an insulation bin 110, an upper cover 120 and a bottom plate 130, the upper cover 120 and the top opening of the insulation bin 110 are detachably connected together by means of snap connection, bolt connection, etc., and are used to close the insulation bin 110, the bottom plate 130 is connected to the bottom of the insulation bin 110, and a plurality of legs 140 may be provided on the bottom plate 130. Among them, the insulation bin 110 and the bottom plate 130 may be integrated or detachably connected. The bottom plate 130 and the legs 140 may be integrated or detachably connected. In this embodiment, four legs 140 are provided.
[0035] The heat preservation chamber 110 has a cavity for placing the reaction cup 90. The heat preservation chamber 110 may be provided with a heating film 203 and a temperature sensor 206 for regulating the temperature in the heat preservation chamber 110. The heat preservation chamber 110 may be made of a heat-insulating material for heat insulation. The cross section of the heat preservation chamber 110 may be square, circular or other shapes.
[0036] At least one functional opening 123 is also provided on the upper cover 120, and the functional opening 123 can be used to add samples and reagents to the reaction cup 90 in the heat preservation chamber 110, extract samples, grab and place the reaction cup 90, and observe the situation in the heat preservation chamber 110 in real time. The number and position of the functional openings 123 can be designed as needed.
[0037] A main control panel 170 is disposed on the bottom plate 130 . The main control panel 170 may be provided with button switches and a display screen, and is electrically connected to the components of the reaction cup mixing device 10 for control.
[0038] Please refer to Figure 2, which is a partial structural diagram of a reaction cup mixing device 10 shown in an embodiment of the present application. The reaction cup mixing device 10 also includes: an incubation disk 200, a mixing rotating disk 300 and at least one friction strip 400. The incubation disk 200 is arranged in the heat preservation bin 110 of the frame 100, and at least one mounting groove 210 for mounting the reaction cup 90 is opened on the upper surface of the incubation disk 200; the mixing rotating disk 300 is arranged in the heat preservation bin 110 of the frame 100 and is located above the incubation disk 200; the mixing rotating mechanism 500 is connected to the mixing rotating disk 300 in a transmission manner, and is used to drive the mixing rotating disk 300 to rotate; the friction strip 400 is fixed on the mixing rotating disk 300, and is used to contact with the reaction cup 90 to drive the reaction cup 90 to rotate.
[0039] During an operation, the mixing rotation mechanism 500 drives the mixing rotation disk 300 to rotate periodically, thereby driving the friction strip 400 fixed on the mixing rotation disk 300 to rotate periodically. The friction strip 400 can contact the reaction cup 90 installed in the incubation disk 200, causing the reaction cup 90 to vibrate and drive the reaction cup 90 to rotate. The rotation of the reaction cup 90 causes the liquid in the reaction cup 90 to generate an oscillating force, thereby mixing the liquid in the reaction cup 90, and the mixing effect is relatively uniform.
[0040] Therefore, in this embodiment, the mixing rotating disk 300 is driven to rotate by the mixing rotating mechanism 500, and the friction strip 400 can contact the reaction cup 90 installed in the incubation disk 200 to drive the reaction cup 90 to rotate, so that the liquid in the reaction cup 90 is mixed, and the mixing effect is relatively uniform.
[0041] Please refer to Figure 3 , which is a schematic diagram of the structure of the incubation disk 200 and the mixing rotating disk 300 in the reaction cup mixing device 10 shown in an embodiment of the present application. A plurality of mounting grooves 210 are provided, and the plurality of mounting grooves 210 are divided into a first group of grooves 211 and a second group of grooves 212. The mounting grooves 210 in the first group of grooves 211 are distributed in a circular array around the axis of the incubation disk 200, and the mounting grooves 210 in the second group of grooves 212 are distributed in a circular array around the axis of the incubation disk 200, and the second group of grooves 212 are located outside the first group of grooves 211. The spacing between two adjacent reaction cups 90 in the second group of grooves 212 may be equal to or different from the spacing between two adjacent reaction cups 90 in the first group of grooves 211.
[0042] In this embodiment, there are 50 mounting slots 210 in the first group of slots 211, and 50 mounting slots 210 in the second group of slots 212, so there are a total of 100 mounting slots 210. The spacing between two adjacent reaction cups 90 in the second group of slots 212 is greater than the spacing between two adjacent reaction cups 90 in the first group of slots 211. In another embodiment, there is one mounting slot 210 in the first group of slots 211, and one mounting slot 210 in the second group of slots 212, so there are a total of two mounting slots 210.
[0043] Accordingly, a plurality of friction strips 400 are provided, and the plurality of friction strips 400 are divided into a first group of strips 401 and a second group of strips 402, and the second group of strips 402 are located outside the first group of strips 401. The first group of strips 401 are located inside the first group of grooves 211, and the friction strips 400 in the first group of strips 401 are used to drive the reaction cups 90 in the first group of grooves 211 to rotate; the second group of strips 402 are located inside the second group of grooves 212, and the friction strips 400 in the second group of strips 402 are used to drive the reaction cups 90 in the second group of grooves 212 to rotate.
[0044] The mixing rotating disk 300 is coaxially arranged with the incubation disk 200. There are a plurality of friction strips 400 in the first group of strips 401, and each friction strip 400 in the first group of strips 401 is distributed in a circular array around the axis of the mixing rotating disk 300, and there are a plurality of friction strips 400 in the second group of strips 402, and each friction strip 400 in the second group of strips 402 is distributed in a circular array around the axis of the mixing rotating disk 300.
[0045] In this embodiment, there are three friction strips 400 in the first group of strips 401, and three friction strips 400 in the second group of strips 402, so there are a total of six friction strips 400. In another embodiment, there is one friction strip 400 in the first group of strips 401, and one friction strip 400 in the second group of strips 402, so there are a total of two friction strips 400.
[0046] The circumferential length of the friction strip 400 is greater than the diameter of the mounting groove 210. In this way, one friction strip 400 can contact multiple reaction cups 90 at the same time, thereby improving the mixing efficiency.
[0047] An annular groove 220 is provided on the upper surface of the incubation tray 200 and between the first group of grooves 211 and the second group of grooves 212. With such a configuration, the space between the reaction cups 90 installed in the first group of grooves 211 and the reaction cups 90 installed in the second group of grooves 212 can be increased, thereby avoiding the rotation of the second group of bars 402 to a certain extent, and reducing the mutual influence between the second group of bars 402, the reaction cups 90 installed in the first group of grooves 211, and the reaction cups 90 installed in the second group of grooves 212.
[0048] An identifier 230 is provided on the upper surface of the incubation tray 200 and the inner surface of the annular groove 220 to distinguish the mounting groove 210 and identify the angle.
[0049] Please refer to Figure 4 , which is a side view of a cuvette mixing device 10 shown in an embodiment of the present application. The cuvette mixing device 10 further includes: an incubation rotating mechanism 600, which is disposed on the frame 100 and is transmission-connected to the incubation tray 200, and is used to drive the incubation tray 200 to rotate.
[0050] During an operation, the incubation tray 200 can be driven to rotate by the incubation rotating mechanism 600, thereby driving the reaction cup 90 installed on the incubation tray 200 to rotate around the axis of the incubation tray 200, so that the designated reaction cup 90 is rotated to a designated position, so that the designated reaction cup 90 can be observed, samples can be added, the reaction cup 90 can be grasped and released, reagents can be added, or samples can be extracted through the functional opening 123.
[0051] In the mixing process of the reaction cup 90, the mixing rotating disk 300 can be driven to rotate forwardly by the mixing rotating mechanism 500, and the incubation disk 200 can be driven to rotate reversely by the incubation rotating mechanism 600, thereby improving the mixing efficiency and mixing effect.
[0052] Please refer to Figure 5 , which is an exploded view of a reaction cup mixing device 10 shown in an embodiment of the present application. A first through hole 121 is provided on the upper cover 120; the mixing rotating mechanism 500 includes: a first rotating driving member 510 and a first transmission mechanism 520, the first rotating driving member 510 can be a driving member such as a stepping motor, and has a first main shaft 511; the first rotating driving member 510 is provided on the upper cover 120, and the first main shaft 511 passes through the first through hole 121 and extends into the heat preservation chamber 110; the first transmission mechanism 520 is provided in the heat preservation chamber 110, and the first main shaft 511 and the mixing rotating disk 300 are connected by transmission.
[0053] Among them, the first transmission mechanism 520 can be a gear transmission, a belt transmission or other transmission methods. In this embodiment, the first transmission mechanism 520 includes a driving gear 521 and a driven gear 522, the driving gear 521 is connected to the first main shaft 511 of the first rotating drive member 510, and the driven gear 522 is fixed to the mixing rotating disk 300 by bolt connection or the like. The driving gear 521 is a small gear, and the driven gear 522 is a large gear. The number of teeth of the driving gear 521 is less than the number of teeth of the driven gear 522, the outer diameter of the driven gear 522 is less than the outer diameter of the mixing rotating disk 300, and the driven gear 522 and the mixing rotating disk 300 are coaxially arranged. Then, the first transmission mechanism 520 is a reduction transmission mechanism. With such an arrangement, the mixing rotating disk 300 can rotate stably.
[0054] The upper cover 120 is connected with a dust cover 512, which is arranged outside the first rotating driving member 510 for dust prevention. The dust cover 512 is also provided with a plurality of holes for heat dissipation.
[0055] Please refer to Figure 6 , which is an exploded view of the reaction cup mixing device 10 shown in an embodiment of the present application. A second through hole 131 is provided on the bottom plate 130, and a third through hole 111 is provided on the heat preservation chamber 110; the incubation rotating mechanism 600 includes: a central axis 610, a second rotating driving member 620, a second transmission mechanism 630 and a support frame 640, and the central axis 610 passes through the second through hole 131 and the third through hole 111 and is connected to the incubation tray 200; the second rotating driving member 620 can be a driving component such as a stepping motor, and has a second main shaft 621; the second transmission mechanism 630 is provided on the bottom plate 130, and is connected to the second main shaft 621 and the incubation tray 200 by transmission; the support frame 640 is respectively connected to the second rotating driving member 620 and the frame 100; wherein the second rotating driving member 620, the support frame 640 and the first rotating driving member 510 are all provided on the outside of the heat preservation chamber 110, and are all provided on the other side of the bottom plate 130 relative to the incubation tray 200.
[0056] Among them, the second transmission mechanism 630 can be gear transmission, belt transmission or other transmission methods. In this embodiment, the second transmission mechanism 630 includes a synchronous belt 631, a driving pulley 632 and a driven pulley 633, the driving pulley 632 is connected to the second main shaft 621 of the second rotating drive member 620, and the driven pulley 633 is connected to the central axis 610. The driving pulley 632 is a small pulley, the driven pulley 633 is a large pulley, the outer diameter of the driven pulley 633 is smaller than the outer diameter of the incubation tray 200, and the driven pulley 633 is coaxially arranged with the incubation tray 200, then the first transmission mechanism 520 is a reduction transmission mechanism, so that the incubation tray 200 can rotate stably.
[0057] A connecting frame 150 is fixed to the bottom plate 130 of the frame 100 by bolt connection, and the reaction cup mixing device 10 also includes: a counting mechanism 700, the counting mechanism 700 includes a code disk 710 and a counting optical coupler 720, the counting optical coupler 720 is fixed to the connecting frame 150 of the frame 100 by bolt connection, the code disk 710 is transmission-connected with the incubation disk 200, and the code disk 710 is fixed to the driven pulley 633 by bolt connection. The code disk 710 is provided with a plurality of notches corresponding to the mounting slots 210, and when the rotating disk rotates, the code disk 710 rotates synchronously, and the counting optical coupler 720 can be used to detect the rotation angle of the incubation disk 200, thereby determining the number of the mounting slots 210, i.e., the reaction cups 90, that have been rotated.
[0058] The cuvette mixing device 10 further includes: a zero position mechanism 800, the zero position mechanism 800 includes a zero position baffle 810 and a zero position optical coupler 820, the zero position optical coupler 820 is fixed to the connecting frame 150 of the frame 100 by bolt connection, and the zero position baffle 810 is fixed to the code disk 710 by bolt connection. When the code disk 710 rotates, the zero position baffle 810 rotates synchronously, so that the zero position baffle 810 can be set to zero position, and when the zero position baffle 810 reaches the zero position optical coupler 820 for the second time, the code disk 710, that is, the incubation disk 200, rotates one circle, so the zero position mechanism 800 can be used to detect the number of circles the incubation disk 200 rotates.
[0059] The friction strip 400 includes a rubber strip 410 and a fixing seat 420. The rubber strip 410 and the fixing seat 420 are fixed together by bolt connection. The fixing seat 420 and the mixing rotating disk 300 are fixed together by bolt connection. The rubber strip 410 is provided with an arc-shaped protrusion 411. The friction strip 400 contacts the reaction cup 90 through the arc-shaped protrusion 411. The outer surface of the arc-shaped protrusion 411 is an arc-shaped curved surface, and the cross section of the arc-shaped protrusion 411 is a crescent shape, so that the strong collision between the friction strip 400 and the reaction cup 90 can be reduced, and the reaction cup 90 is prevented from falling out of the mounting groove 210.
[0060] A fourth through hole 310 is provided on the mixing rotating disk 300, and the reaction cup mixing device 10 further includes: at least one first bearing seat 311 and at least one first bearing 312, the first bearing seat 311 is provided in the fourth through hole 310, the first bearing 312 is installed in the fourth through hole 310 through the first bearing seat 311, and is sleeved on the central shaft 610. In this embodiment, one first bearing seat 311 and one first bearing 312 are provided. The first bearing 312 is a deep groove ball bearing, so that the friction coefficient of the central shaft 610 can be reduced during the movement.
[0061] The reaction cup mixing device 10 also includes: at least one second bearing insulation member 611, at least one second bearing seat 612 and at least one second bearing 613. The second bearing insulation member 611 is arranged in the second through hole 131 and the third through hole 111. The second bearing insulation member 611 is made of heat-insulating material and is used to prevent the heat of the bearing from overflowing and affecting the reaction cup 90 in the incubation tray 200. The second bearing seat 612 is arranged in the second bearing insulation member 611. The second bearing 613 is installed in the second through hole 131 and the third through hole 111 through the second bearing seat 612, and is sleeved on the central shaft 610. In this embodiment, the second bearing seat 612 and the second bearing insulation member 611 are each provided with one, and the second bearing 613 is provided with two. The second bearing 613 is a deep groove ball bearing, so that the friction coefficient of the central shaft 610 can be reduced during the movement.
[0062] The incubation tray 200 includes an incubation outer ring 201, an incubation inner ring 202, a heating film 203, a temperature control switch 204, a wire pressing plate 205 and a temperature sensor 206. The mounting groove 210 is arranged on the incubation outer ring 201, and the incubation inner ring 202 is fixed to the incubation outer ring 201 by bolt connection or the like; the heating film 203 is fixed to the incubation inner ring 202 by snap connection or the like; the temperature control switch 204 is fixed to the incubation inner ring 202 by snap connection or the like, and is electrically connected to the heating film 203; two wire pressing plates 205 are provided, which are fixed to the incubation inner ring 202 by snap connection or the like, and are electrically connected to the heating film 203; two temperature sensors 206 are provided, which are PT100 nose pressure type-3 meter line fixed to the incubation inner ring 202 for temperature measurement. Therefore, in this embodiment, the incubation tray 200 is heated by the heating film 203 , and the temperature is controlled by the temperature control switch 204 and the temperature sensor 206 .
[0063] Please refer to Figure 7 , which is a bottom view of a reaction cup mixing device 10 shown in one embodiment of the present application. Figure 8 , which is a cross-sectional view of a reaction cup mixing device 10 shown in an embodiment of the present application. The central axis 610, the first bearing 312, the second bearing 613, the heat preservation chamber 110, the upper cover 120, the mixing rotating disk 300, and the incubation disk 200 are all coaxially arranged. The central axis 610 is a hollow stepped shaft, and the axial displacement of the first bearing 312, the second bearing 613 and the incubation disk 200 can be limited by a flange, a groove or a retaining ring. A sealing ring 160 is provided between the heat preservation chamber 110 and the upper cover 120 for sealing.
[0064] A friction member 91 is provided on the inner surface of the reaction cup 90. The friction member 91 may be a convex rib. When the reaction cup 90 vibrates, the friction member 91 in the reaction cup 90 may "rub" with the liquid in the reaction cup 90, thereby improving the mixing effect and allowing the liquid in the reaction cup 90 to fully react, thereby improving the detection effect. In another embodiment, the friction member 91 may not be provided in the reaction cup 90, and the inner wall may be smooth.
[0065] It should be noted that, in the absence of conflict, the features in the embodiments of this application may be combined with each other.
[0066] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A reaction cup mixing device, characterized in that: include: frame; An incubation tray, arranged on the rack, and provided with at least one mounting slot for mounting a reaction cup; A mixing rotating disk is arranged on the frame and located above the incubation disk; A mixing and rotating mechanism, which is arranged on the frame and is drivingly connected to the mixing and rotating disk, and is used to drive the mixing and rotating disk to rotate; as well as At least one friction strip, fixed on the mixing rotating disk, used for contacting the reaction cup to drive the reaction cup to rotate; Wherein, the frame comprises: a heat preservation chamber and an upper cover arranged on the top of the heat preservation chamber, and the incubation plate and the mixing rotating plate are both arranged in the heat preservation chamber; The plurality of mounting grooves are divided into a first group of grooves and a second group of grooves, the respective mounting grooves in the first group of grooves are distributed in a circular array around the axis of the incubation tray, the respective mounting grooves in the second group of grooves are distributed in a circular array around the axis of the incubation tray, and the second group of grooves are located outside the first group of grooves; The friction strips are provided in plurality, and the plurality of friction strips are divided into a first group of strips and a second group of strips, wherein the second group of strips is located outside the first group of strips, the friction strips in the first group of strips are used to drive the reaction cups in the first group of slots to rotate, and the friction strips in the second group of strips are used to drive the reaction cups in the second group of slots to rotate; The circumferential length of the friction strip is greater than the diameter of the mounting groove.
2. The reaction cup mixing device according to claim 1, characterized in that: The mixing rotating disk and the incubation disk are coaxially arranged.
3. The reaction cup mixing device according to claim 2, characterized in that: There are multiple friction strips in the first group of strips, and the individual friction strips in the first group of strips are distributed in a circular array around the axis of the mixing rotating disk. There are multiple friction strips in the second group of strips, and the individual friction strips in the second group of strips are distributed in a circular array around the axis of the mixing rotating disk.
4. The reaction cup mixing device according to any one of claims 1 to 3, characterized in that: The upper cover is provided with a first through hole; The mixing and rotating mechanism comprises: A first rotating driving member having a first main shaft; the first rotating driving member is disposed on the upper cover, and the first main shaft passes through the first through hole and extends into the heat preservation chamber; and The first transmission mechanism is arranged in the heat preservation chamber and is transmission-connected to the first main shaft and the mixing rotating disk.
5. The reaction cup mixing device according to claim 4, characterized in that: The reaction cup mixing device also includes: The incubation rotating mechanism is arranged on the frame and is drivingly connected with the incubation tray to drive the incubation tray to rotate.
6. The reaction cup mixing device according to claim 5, characterized in that: The frame further comprises: a bottom plate arranged at the bottom of the heat preservation bin, the bottom plate is provided with a second through hole, and the heat preservation bin is provided with a third through hole. The incubation rotating mechanism comprises: A central axis, passing through the second through hole and the third through hole and then connected to the incubation plate; A second rotary drive member having a second main shaft; A second transmission mechanism, disposed on the bottom plate, transmission-connecting the second spindle and the incubation tray; and A support frame, connected to the second rotating driving member and the frame respectively; Wherein, the second rotating driving member, the supporting frame and the first rotating driving member are all arranged on the outside of the heat preservation chamber, and are all arranged on the other side of the bottom plate relative to the incubation tray.
7. The reaction cup mixing device according to claim 6, characterized in that: The mixing rotating disk is provided with a fourth perforation, and the reaction cup mixing device further comprises: At least one first bearing is disposed in the fourth through hole and sleeved on the central axis.
8. The reaction cup mixing device according to claim 5, characterized in that: The reaction cup mixing device also includes: A counting mechanism, comprising a code disk and a counting optical coupler, wherein the counting optical coupler is arranged on a frame, and the code disk is drivingly connected to the incubation disk; and The zero position mechanism comprises a zero position baffle and a zero position optical coupler, wherein the zero position optical coupler is arranged on the frame, and the zero position baffle is arranged on the code disc.
Citation Information
Patent Citations
Reaction cup and reaction cup uniform mixing device
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