A cooling device for a magnetic stimulation system and a magnetic stimulation system

Abstract

The present application discloses a cooling device and a magnetic stimulation system for a magnetic stimulation system, including a coil liquid cooling loop, a secondary liquid cooling loop, and an air-cooled transducer device. Among them, the secondary liquid cooling loop includes a liquid circulation driving device, a liquid circulation main pipeline, and a first transducer; the air-cooled transducer device includes a heat sink and a fan arranged on the liquid circulation main pipeline; the coil liquid cooling loop includes a coil liquid circulation driving device and a coil cooling circulation pipeline, and the coil cooling circulation pipeline communicates with the pipeline of a magnetic stimulation coil wound by a hollow metal tube. The coil cooling circulation pipeline and the liquid circulation main pipeline perform heat energy interaction through the first transducer. Since the heat energy transfer between the hollow metal tube of the magnetic stimulation coil and the coil cooling circulation pipeline is realized by means of liquid cooling, the heat dissipation speed of the magnetic stimulation coil is faster and safer, and it will not form shielding and interference to the electromagnetic signal emitted by the magnetic stimulation coil.

Description

Technical Field

[0001] This application relates to the technical field of magnetic stimulation systems, and particularly relates to a cooling device for a magnetic stimulation system and a magnetic stimulation system. Background Art

[0002] Transcranial Magnetic Stimulation (TMS) is an important technology in the field of biomedical engineering. It is a technology based on the principle of electromagnetic induction of the brain electric field. Through high-field pulsed electromagnetic fields, it can penetrate the skull and act on nerve tissues at deeper positions for nerve stimulation and nerve regulation. Moreover, it does not require piercing the skin to install the device, and has the advantages of non-invasiveness and painlessness. The magnetic field used for TMS can have an intensity and density sufficient to depolarize neurons. And when TMS pulses are repeatedly applied, when the parameters of magnetic stimulation (frequency, amplitude, pulse width, pulse width gradient, etc.) are selected, transcranial magnetic stimulation can regulate the excitability of the cerebral cortex, and even regulate the excitability of the cortex throughout the stimulation period. In the past few decades, the application of TMS in studying the cognition of various nervous system and mental diseases, the relationship between brain behavior, and pathophysiology has increased rapidly.

[0003] Magnetic Seizure Therapy (MST) refers to the intentional induction of seizures for therapeutic purposes using repetitive transcranial magnetic stimulation (rTMS). Therefore, the equipment used for MST requires a more powerful output function than that used in rTMS because the MST trigger device needs to be able to maintain long trains of stimuli at high frequencies in order to induce controllable seizures in a fully anesthetized patient. The aim of this type of MST convulsive therapy is to achieve the induction of controllable local cerebral seizures and to retain the unique efficacy of electroconvulsive therapy (ECT) in the treatment of mental disorders while minimizing the cognitive side effects associated with ECT. For example, magnetic seizure therapy applies a transcranial magnetic stimulation device and coil to generate a series of magnetic pulses of a certain intensity in a patient under general anesthesia, causing the patient to have a seizure. The results of magnetic seizure therapy are theoretically basically the same as those of electroshock. Like ECT, MST also causes generalized seizures and may be alleviated through the same biomedical pathways. Compared with ECT, MST has the following advantages: 1) The magnetic field penetrates tissues without dissipating energy through electrical conductance; 2) The brain stimulation dose can be more accurate and reliable; 3) The stimulation can be limited to the brain structures necessary for the therapeutic response, thus reducing the side effects associated with ECT, such as memory impairment. At the same time, compared with ECT, MST has a shorter seizure duration, lower electroencephalogram amplitudes during seizures, and less post-seizure inhibition. Also, compared with ECT, MST patients have fewer subjective side effects and a faster recovery direction.

[0004] Both TMS and MST magnetic stimulation devices use special coils to generate magnetic pulses to stimulate specific parts of patients, such as central parts like the brain and spine, and can also stimulate peripheral parts like the trunk and limbs. Since the magnetic field strength generated by the coil is inversely proportional to the square of the transmission distance of the magnetic field, and the attenuation of the magnetic field passing through the skin, muscles, etc., the magnetic field strength generated by the coil decays rapidly when used in TMS and MST devices. To produce an effective stimulation effect in the body at a specific depth, such as the cerebral cortex, the magnetic stimulation device must generate a strong enough magnetic field strength to meet the requirements. The magnetic field generated by the TMS device coil generally needs to reach 1.5 Tesla, and the magnetic field generated by the MST device coil needs to reach more than 4.0 Tesla. The driving voltage of TMS and MST coils is generally above 1500V, usually 1500V - 3000V, and the driving current is above 100A. Calculated with a typical 150 - 450uS pulse width rectangular pulse, with a voltage of 1500V and a current of 100A, about 22.5W of electrical energy needs to be delivered to the coil for 1 magnetic stimulation pulse. The common stimulation frequency of TMS is 30 - 150HZ, and its power will reach more than 675W. The stimulation frequency of MST may reach above 100HZ, and its power may reach more than 2250W. A small part of the energy driving the coil is converted into magnetic energy, and most of it will be converted into heat at the stimulation coil. Since the stimulation coils of TMS and MST magnetic stimulation devices are high-voltage and high-current, the stimulation coils need to be prepared with special protective materials and processes, and the heat dissipation effect of the magnetic stimulation coils is generally poor, resulting in the rapid temperature rise of the magnetic stimulation coils in a very short time, causing explosions, fires, etc. of the stimulation coils, bringing potential safety hazards. Similarly, the high power, high voltage, and high current of the overall TMS and MST devices also make the heat dissipation of the device host part an urgent problem to be solved. Obviously, when a single host in TMS and MST devices drives multiple coil outputs simultaneously, the magnetic stimulation coil and host heat dissipation problems faced by such a comprehensive magnetic stimulation device will be more serious.

[0005] MST devices have a greater power supply requirement than standard rTMS devices. To meet the high-power requirements of MST devices, companies such as MagStim and MagVenture have adopted the method of stacking multiple rTMS devices to construct MST treatment devices. Stacking multiple standard rTMS devices will not only cause the cost of MST devices to increase extremely, but also, due to the large power output of the magnetic stimulation device, the heat generation of the magnetic stimulation device is very concentrated, resulting in a very high heat generation of the magnetic stimulation host, especially the magnetic stimulation coil. MST devices generally need to stop for cooling for more than half an hour after continuously outputting for 10s or 8s, and the working efficiency of MST is very low. In view of the characteristics of concentrated heat generation and difficult heat dissipation of magnetic stimulation devices, it is urgent to develop a new and efficient cooling system for magnetic stimulation devices. Summary of the Invention

[0006] The main technical problem to be solved by the present invention is that when the magnetic stimulation coil in the existing transcranial magnetic stimulation device works, due to the high working current and voltage, the heat generation is very high, and good heat dissipation is required.

[0007] According to a first aspect, in one embodiment, a cooling device for a magnetic stimulation system is provided, including a coil liquid cooling loop, a secondary liquid cooling loop, and an air-cooled transducer device;

[0008] The coil liquid cooling loop is used to transfer the heat energy generated by the magnetic stimulation coil of the magnetic stimulation system to the secondary liquid cooling loop; the secondary liquid cooling loop is used to transfer the heat energy transferred from the coil liquid cooling loop to the air-cooled transducer device by means of liquid cooling; the air-cooled transducer device is used to dissipate the heat energy of the secondary liquid cooling loop by means of air cooling;

[0009] The secondary liquid cooling loop includes a liquid circulation driving device, a liquid circulation main pipeline, and a first transducer;

[0010] The liquid circulation driving device is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the liquid circulation main pipeline;

[0011] The first transducer is arranged on the liquid circulation main pipeline and is used to realize the heat energy exchange between the coil liquid cooling loop and the secondary liquid cooling loop;

[0012] The air-cooled transducer device includes a fan and a heat sink. The heat sink is arranged on the liquid circulation main pipeline, and the fan is used to dissipate heat from the heat sink;

[0013] The magnetic stimulation coil is wound by a hollow metal tube;

[0014] The coil liquid cooling loop includes a coil liquid circulation driving device and a coil cooling circulation pipeline; the coil cooling circulation pipeline communicates with the pipeline inside the hollow metal tube; the coil liquid circulation driving device is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the coil cooling circulation pipeline and the pipeline inside the hollow metal tube; the coil cooling circulation pipeline is also connected to the first transducer to realize the heat energy transfer between the coil cooling circulation pipeline and the liquid circulation main pipeline through the first transducer; the liquid for conducting heat energy is an insulating liquid.

[0015] In one embodiment, the cooling device further includes a host liquid cooling loop, which is used to transfer the heat energy generated by the coil drive control device of the magnetic stimulation system to the secondary liquid cooling loop by means of liquid cooling; the coil drive control device is used to provide drive electric energy to the magnetic stimulation coil;

[0016] The host liquid cooling loop includes a heat conductor, a host liquid circulation driving device, and a host cooling circulation pipeline;

[0017] The heat conductor is arranged on the host cooling circulation pipeline and is used to transfer the heat energy generated by the coil driving control device to the host cooling circulation pipeline;

[0018] The host liquid circulation driving device is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the host cooling circulation pipeline;

[0019] The secondary liquid cooling loop further includes a second transducer, which is arranged on the liquid circulation main pipeline and the host cooling circulation pipeline; the second transducer is used to realize the heat energy exchange between the host liquid cooling loop and the secondary liquid cooling loop.

[0020] In one embodiment, the cooling device further includes a temperature main control module and a liquid temperature adjusting device;

[0021] The temperature main control module is used to monitor the temperature values of the magnetic stimulation coil and the coil driving control device, and when the obtained temperature values are not within the preset temperature threshold, adjust the temperature of the circulating liquid in the secondary liquid cooling loop through the liquid temperature adjusting device;

[0022] The liquid temperature adjusting device includes a liquid heating device and a liquid cooling device, which are respectively arranged on the liquid circulation main pipeline.

[0023] In one embodiment, the preset temperature threshold is between 15 degrees Celsius and 45 degrees Celsius.

[0024] In one embodiment, the liquid heating device includes an ultrasonic heater;

[0025] And / or, the liquid cooling device includes an electronic condenser.

[0026] In one embodiment, the liquid circulation driving device includes a liquid container and a hydraulic pump.

[0027] According to the first aspect, in one embodiment, a magnetic stimulation system is provided, which includes the cooling device described in the first aspect.

[0028] In one embodiment, the magnetic stimulation system further includes a positioning and fixing connection device and an electromagnetic wave emitting device;

[0029] The positioning and fixing connection device includes a spherical fixing frame, and the spherical fixing frame is composed of two identical hemispherical frames; the spherical fixing frame is used to fixedly connect the head and set the target area to be magnetically stimulated at the center point of the spherical fixing frame;

[0030] The electromagnetic wave emitting device includes a magnetic stimulation coil and a coil driving and controlling device;

[0031] The magnetic stimulation coil includes a first electromagnetic generating coil group, a second electromagnetic generating coil group, and a third electromagnetic generating coil group; the first electromagnetic generating coil group includes two first coils with the same structure, and the two first coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame; the second electromagnetic generating coil group includes two second coils with the same structure, and the two second coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame; the third electromagnetic generating coil group includes two third coils with the same structure, and the two third coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame;

[0032] The first electromagnetic generating coil group, the second electromagnetic generating coil group, and the third electromagnetic generating coil group are respectively used to form a pair of dual-focus magnetic stimulation coil pairs to emit electromagnetic waves to the center point of the spherical fixing frame for magnetic stimulation of the target area;

[0033] The coil driving and controlling device is used to provide driving electric energy to the magnetic stimulation coil.

[0034] In one embodiment, the coil driving and controlling device is used to perform timing control of the driving current of the first coil of the first electromagnetic generating coil group, the second coil of the second electromagnetic generating coil group, and the third coil of the third electromagnetic generating coil group simultaneously or respectively according to a preset magnetic stimulation intensity and magnetic stimulation timing sequence.

[0035] In one embodiment, the current of the coil driving and controlling device for driving the first coil, the second coil, and the third coil is 1A to 10kA;

[0036] And / or, the frequency of the coil driving and controlling device for driving the first coil, the second coil, and the third coil is 1KHz to 10KHz.

[0037] According to the cooling device of the above embodiment, since the heat energy transfer between the hollow metal tube of the magnetic stimulation coil and the coil cooling circulation pipeline is realized by means of liquid cooling, the heat dissipation speed of the magnetic stimulation coil is faster and safer, and it will not form shielding and interference to the electromagnetic signal emitted by the magnetic stimulation coil. Description of the Drawings

[0038] Figure 1 It is a schematic structural connection diagram of the cooling device in one embodiment;

[0039] Figure 2 Schematic structural connection diagram of a secondary liquid cooling loop in an embodiment;

[0040] Figure 3 Schematic structural diagram of a magnetic stimulation system in an embodiment. Specific embodiments

[0041] The present invention will be further described in detail below in conjunction with the accompanying drawings through specific embodiments. Similar elements in different embodiments are labeled with related similar element numbers. In the following embodiments, many detailed descriptions are provided to enable a better understanding of the present application. However, those skilled in the art can easily recognize that some of the features can be omitted in different situations, or can be replaced by other elements, materials, or methods. In some cases, some operations related to the present application are not shown or described in the specification to avoid overwhelming the core part of the present application with excessive descriptions. For those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the descriptions in the specification and general technical knowledge in the art.

[0042] In addition, the features, operations, or characteristics described in the specification can be combined in any appropriate manner to form various embodiments. At the same time, the steps or actions in the method description can also be reordered or adjusted in an obvious manner by those skilled in the art. Therefore, the various sequences in the specification and drawings are only for clearly describing a certain embodiment and do not mean that they are necessary sequences, unless it is stated that a certain sequence must be followed.

[0043] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the described objects and do not have any sequential or technical meaning. And the "connection" and "coupling" mentioned in the present application, unless otherwise specified, both include direct and indirect connection (coupling).

[0044] The cooling system in the embodiments of the present application is used for a magnetic stimulation system. By using a dual liquid circulation system, it realizes the isolation of the cooling circulation of the magnetic stimulation host and the magnetic stimulation coil and the main cooling circulation system. By using methods such as an electronic condenser, a hot and cold liquid transducer, an ultrasonic heating technique, and air circulation heat dissipation, it realizes the intelligent temperature control of the magnetic stimulation host and the magnetic stimulation coil, thereby ensuring the continuous and stable operation of the magnetic stimulation system and greatly improving the safety of the magnetic stimulation system.

[0045] Embodiment 1

[0046] Please refer to Figure 1, is a schematic structural connection diagram of a cooling device in an embodiment. The cooling device is used for a magnetic stimulation system. Among them, the magnetic stimulation system includes a magnetic stimulation coil and a coil drive control device. The coil drive control device is used to provide driving electric energy to the magnetic stimulation coil, and the magnetic stimulation coil is wound by a hollow metal tube. The cooling device includes a coil liquid cooling loop 20, a secondary liquid cooling loop 40, and an air-cooled energy conversion device 50. The coil liquid cooling loop 20 is used to transfer the heat energy generated by the magnetic stimulation coil of the magnetic stimulation system to the secondary liquid cooling loop 40. The secondary liquid cooling loop 40 is used to transfer the heat energy transferred from the coil liquid cooling loop to the air-cooled energy conversion device 50 by means of liquid cooling. The air-cooled energy conversion device 50 is used to dissipate the heat energy of the secondary liquid cooling loop 40 by means of air cooling.

[0047] Please refer to Figure 2 , is a schematic structural connection diagram of a secondary liquid cooling loop in an embodiment. The secondary liquid cooling loop 40 includes a liquid circulation drive device 43, a liquid circulation main pipeline 42, and a first transducer 41. The liquid circulation drive device 43 is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the liquid circulation main pipeline 42. The first transducer 41 is arranged on the liquid circulation main pipeline 42 and is used to realize the heat energy exchange between the coil liquid cooling loop 20 and the secondary liquid cooling loop 40. The air-cooled energy conversion device 50 includes a fan and a heat sink. The heat sink is arranged on the liquid circulation main pipeline 42, and the fan is used to perform air-cooled heat dissipation on the heat sink. Since the magnetic stimulation coil is wound by a hollow metal tube, the hollow metal tube can be used as a circulating pipeline for liquid cooling. The coil liquid cooling loop 20 includes a coil liquid circulation drive device 22 and a coil cooling circulation pipeline 21. The coil cooling circulation pipeline 21 communicates with the pipeline inside the hollow metal tube. The coil liquid circulation drive device 22 is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the coil cooling circulation pipeline 21 and the pipeline inside the hollow metal tube. The coil cooling circulation pipeline 21 is also connected to the first transducer 41 to realize the heat energy transfer between the coil cooling circulation pipeline 21 and the liquid circulation main pipeline 42 through the first transducer 41. Among them, the liquid for conducting heat energy is an insulating liquid.

[0048] As Figure 1 shown, in an embodiment, the cooling device further includes a host liquid cooling loop 30, which is used to transfer the heat energy generated by the coil drive control device of the magnetic stimulation system to the secondary liquid cooling loop 40 by means of liquid cooling. Among them, the coil drive control device is used to provide driving electric energy to the magnetic stimulation coil. As Figure 2As shown, the host liquid cooling loop 30 includes a heat conductor 31, a host liquid circulation driving device 33, and a host cooling circulation pipeline 32. The heat conductor 31 is arranged on the host cooling circulation pipeline 32 and is used to transfer the heat energy generated by the coil driving control device to the host cooling circulation pipeline 32. The host liquid circulation driving device 33 is used to provide the power for liquid circulation so that the liquid for conducting heat energy circulates in the host cooling circulation pipeline 32. The secondary liquid cooling loop 40 further includes a second transducer 44, which is arranged on the main liquid circulation pipeline 42 and the host cooling circulation pipeline 32, and the second transducer 44 is used to realize the heat energy exchange between the host liquid cooling loop 30 and the secondary liquid cooling loop 40.

[0049] For another example Figure 1 As shown, in one embodiment, the cooling device further includes a temperature main control module 10 and a liquid temperature regulating device 60. The temperature main control module 10 is used to monitor the temperature values of the magnetic stimulation coil and the coil driving control device, and when the obtained temperature values are not within the preset temperature thresholds, it adjusts the temperature of the circulating liquid in the secondary liquid cooling loop through the liquid temperature regulating device 60 to keep the temperature values of the magnetic stimulation coil and the coil driving control device within the preset temperature thresholds. In one embodiment, the liquid temperature regulating device 60 includes a liquid heating device and a liquid cooling device, which are respectively arranged on the main liquid circulation pipeline of the secondary liquid cooling loop. In one embodiment, the preset temperature thresholds are between 15 degrees Celsius and 45 degrees Celsius. In one embodiment, the liquid heating device includes an ultrasonic heater. In one embodiment, the liquid cooling device includes an electronic condenser. In one embodiment, the liquid circulation driving device of the secondary liquid cooling loop includes a liquid container and a hydraulic pump.

[0050] Please refer to Figure 3, is a schematic structural diagram of a magnetic stimulation system in an embodiment. The magnetic stimulation system includes the cooling device as described above, and further includes a positioning and fixing connection device and an electromagnetic wave emitting device. The positioning and fixing connection device includes a spherical fixing frame 1, and the spherical fixing frame 1 is composed of two identical hemispherical frames. The spherical fixing frame 1 is used to fixedly connect the head and set the target area to be magnetically stimulated at the center point of the spherical fixing frame 1. The electromagnetic wave emitting device includes a magnetic stimulation coil and a coil driving and controlling device. The magnetic stimulation coil includes a first electromagnetic generating coil group, a second electromagnetic generating coil group, and a third electromagnetic generating coil group. The first electromagnetic generating coil group includes two first coils 11 with the same structure, and the two first coils 11 are symmetrically arranged on the spherical fixing frame 1 of the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame 1. The second electromagnetic generating coil group includes two second coils 12 with the same structure, and the two second coils 12 are symmetrically arranged on the spherical fixing frame 1 of the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame 1. The third electromagnetic generating coil group includes two third coils 13 with the same structure, and the two third coils 13 are symmetrically arranged on the spherical fixing frame 1 of the positioning and fixing connection device in a central symmetry manner, and the central symmetry point coincides with the center point of the spherical fixing frame 1. The first electromagnetic generating coil group, the second electromagnetic generating coil group, and the third electromagnetic generating coil group are respectively used to form a pair of dual-focus magnetic stimulation coil pairs to emit electromagnetic waves to the center point of the spherical fixing frame 1 for magnetic stimulation of the target area.

[0051] The coil driving and controlling device is used to provide driving electric energy to the magnetic stimulation coil. In one embodiment, the coil driving and controlling device is used to perform timing control of the driving current on the first coil of the first electromagnetic generating coil group, the second coil of the second electromagnetic generating coil group, and the third coil of the third electromagnetic generating coil group simultaneously or respectively according to a preset magnetic stimulation intensity and magnetic stimulation timing sequence. In one embodiment, the current of the coil driving and controlling device for driving the first coil, the second coil, and the third coil is 1A to 10kA. In one embodiment, the frequency of the coil driving and controlling device for driving the first coil, the second coil, and the third coil is 1KHz to 10KHz.

[0052] In one embodiment, when as Figure 3When the electromagnetic wave emitting device shown is used to perform magnetic stimulation on the cerebral cortex, the magnetic field generated by the coil needs to reach 1.5 Tesla, the voltage needs to reach 1500V - 3000V, and the driving current needs to reach more than 100A. Calculated with a typical rectangular pulse with a pulse width of 150 - 450 μs, with a voltage of 1500V and a current of 100A, about 22.5W of electrical energy needs to be delivered to the coil for one magnetic stimulation pulse. The stimulation frequency is 30 - 150HZ, and its power will reach more than 675W. Most of the electrical energy of the electromagnetic wave emitting device is converted into heat energy, and the magnetic stimulation coil will quickly heat up in a very short time. To ensure the safe and stable operation of the magnetic stimulation system, cooling and temperature reduction are carried out through the cooling device described above.

[0053] This application discloses a cooling device for a magnetic stimulation system, which includes a coil liquid cooling loop, a secondary liquid cooling loop, and an air-cooled transducer device. Among them, the secondary liquid cooling loop includes a liquid circulation driving device, a liquid circulation main pipeline, and a first transducer; the air-cooled transducer device includes a heat sink and a fan arranged on the liquid circulation main pipeline; the coil liquid cooling loop includes a coil liquid circulation driving device and a coil cooling circulation pipeline, and the coil cooling circulation pipeline communicates with the pipeline of the magnetic stimulation coil wound by a hollow metal tube. The coil cooling circulation pipeline and the liquid circulation main pipeline perform heat energy interaction through the first transducer. Since the heat energy transfer between the hollow metal tube of the magnetic stimulation coil and the coil cooling circulation pipeline is realized through the liquid cooling method, the heat dissipation speed of the magnetic stimulation coil is faster and safer, and it will not form shielding and interference to the electromagnetic signal emitted by the magnetic stimulation coil.

[0054] Compared with the prior art, this application uses a dual liquid circulation system and an air circulation system to isolate the cooling circulation of the magnetic stimulation host and the magnetic stimulation coil and the main cooling circulation system. By using methods such as an electronic condenser, a hot and cold liquid transducer, ultrasonic heating technology, and air circulation heat dissipation, intelligent control of the magnetic stimulation host and the magnetic stimulation coil at 15 degrees Celsius to 45 degrees Celsius is achieved. Continuous operation of the magnetic stimulation device can be realized, and the safety performance of the magnetic stimulation device can be greatly improved.

[0055] Those skilled in the art can understand that all or part of the functions of the various methods in the above embodiments can be implemented in a hardware manner or in a computer program manner. When all or part of the functions in the above embodiments are implemented in a computer program manner, the program can be stored in a computer-readable storage medium, and the storage medium can include: read-only memory, random access memory, magnetic disk, optical disk, hard disk, etc. The above functions can be realized by a computer executing the program. For example, the program is stored in the memory of the device, and when the processor executes the program in the memory, the above all or part of the functions can be realized. In addition, when all or part of the functions in the above embodiments are implemented in a computer program manner, the program can also be stored in a storage medium such as a server, another computer, magnetic disk, optical disk, flash drive or mobile hard disk, and saved to the memory of the local device by downloading or copying, or the system of the local device is updated. When the processor executes the program in the memory, all or part of the functions in the above embodiments can be realized.

[0056] The above uses specific examples to elaborate on the present invention, which is only used to help understand the present invention and is not intended to limit the present invention. For those skilled in the art of the present invention, according to the idea of the present invention, several simple deductions, deformations or substitutions can also be made.

Claims

1. A magnetic stimulation system, characterized in that, it includes a cooling device, a positioning and fixing connection device, and an electromagnetic wave emitting device; the positioning and fixing connection device includes a spherical fixing bracket, and the spherical fixing bracket is composed of two identical hemispherical frames; the spherical fixing bracket is used to fixedly connect the skull, and the target area to be magnetically stimulated is set at the center point of the spherical fixing bracket; the electromagnetic wave emitting device includes a magnetic stimulation coil and a coil driving and controlling device; the magnetic stimulation coil includes a first electromagnetic generating coil group, a second electromagnetic generating coil group, and a third electromagnetic generating coil group; the first electromagnetic generating coil group includes two first coils with the same structure, and the two first coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point is located at the center point of the spherical fixing bracket; the second electromagnetic generating coil group includes two second coils with the same structure, and the two second coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point is located at the center point of the spherical fixing bracket; the third electromagnetic generating coil group includes two third coils with the same structure, and the two third coils are symmetrically arranged on the positioning and fixing connection device in a central symmetry manner, and the central symmetry point is located at the center point of the spherical fixing bracket; the first electromagnetic generating coil group, the second electromagnetic generating coil group, and the third electromagnetic generating coil group are respectively used to form a pair of dual-focus magnetic stimulation coil pairs to emit electromagnetic waves to the center point of the spherical fixing bracket to magnetically stimulate the target area; the coil driving and controlling device is used to provide driving electric energy to the magnetic stimulation coil; the cooling device includes a coil liquid cooling loop, a secondary liquid cooling loop, and an air-cooling energy conversion device; the coil liquid cooling loop is used to transfer the heat energy generated by the magnetic stimulation coil of the magnetic stimulation system to the secondary liquid cooling loop; the secondary liquid cooling loop is used to transfer the heat energy transferred from the coil liquid cooling loop to the air-cooling energy conversion device in a liquid cooling manner; the air-cooling energy conversion device is used to dissipate the heat energy of the secondary liquid cooling loop by air cooling; the secondary liquid cooling loop includes a liquid circulation driving device, a liquid circulation main pipeline, and a first transducer; the liquid circulation driving device is used to provide the power for liquid circulation so that the liquid for conducting heat energy circulates in the liquid circulation main pipeline; the first transducer is arranged on the liquid circulation main pipeline and is used to realize the heat energy exchange between the coil liquid cooling loop and the secondary liquid cooling loop; the air-cooling energy conversion device includes a fan and a heat sink, the heat sink is arranged on the liquid circulation main pipeline, and the fan is used to dissipate heat from the heat sink; the magnetic stimulation coil is wound by a hollow metal tube; The coil liquid cooling loop includes a coil liquid circulation driving device and a coil cooling circulation pipeline; the coil cooling circulation pipeline communicates with the pipeline inside the hollow metal tube; the coil liquid circulation driving device is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the coil cooling circulation pipeline and the pipeline inside the hollow metal tube; the coil cooling circulation pipeline is also connected to the first transducer to achieve heat energy transfer between the coil cooling circulation pipeline and the liquid circulation main pipeline through the first transducer; the liquid for conducting heat energy is an insulating liquid.

2. The magnetic stimulation system according to claim 1, characterized in that, the cooling device further includes a host liquid cooling loop for transferring the heat energy generated by the coil driving control device of the magnetic stimulation system to the secondary liquid cooling loop in a liquid cooling manner; the coil driving control device is used to provide driving electric energy to the magnetic stimulation coil; the host liquid cooling loop includes a heat conductor, a host liquid circulation driving device and a host cooling circulation pipeline; the heat conductor is arranged on the host cooling circulation pipeline for transferring the heat energy generated by the coil driving control device to the host cooling circulation pipeline; the host liquid circulation driving device is used to provide the power for liquid circulation, so that the liquid for conducting heat energy circulates in the host cooling circulation pipeline; the secondary liquid cooling loop further includes a second transducer arranged on the liquid circulation main pipeline and the host cooling circulation pipeline; the second transducer is used to realize the heat energy exchange between the host liquid cooling loop and the secondary liquid cooling loop.

3. The magnetic stimulation system according to claim 2, characterized in that, the cooling device further includes a temperature main control module and a liquid temperature regulating device; the temperature main control module is used to monitor the temperature values of the magnetic stimulation coil and the coil driving control device, and when the obtained temperature values are not within the preset temperature threshold, adjust the temperature of the circulating liquid in the secondary liquid cooling loop through the liquid temperature regulating device to keep the temperature values of the magnetic stimulation coil and the coil driving control device within the preset temperature threshold; the liquid temperature regulating device includes a liquid heating device and a liquid cooling device, which are respectively arranged on the liquid circulation main pipeline.

4. The magnetic stimulation system according to claim 3, characterized in that, the preset temperature threshold is between 15 degrees Celsius and 45 degrees Celsius.

5. The magnetic stimulation system according to claim 3, characterized in that, the liquid heating device includes an ultrasonic heater; and / or, the liquid cooling device includes an electronic condenser.

6. The magnetic stimulation system according to claim 1, characterized in that, the liquid circulation driving device includes a liquid container and a hydraulic pump.

7. The magnetic stimulation system according to claim 1, characterized in that, the coil driving control device is used to perform timing control of the driving current on the first coil of the first electromagnetic generating coil group, the second coil of the second electromagnetic generating coil group and the third coil of the third electromagnetic generating coil group simultaneously or respectively according to the preset magnetic stimulation intensity and magnetic stimulation timing.

8. The magnetic stimulation system according to claim 7, wherein, the current of the first coil, the second coil, and the third coil driven by the coil drive control device is 1 A to 10 kA; and / or, the frequency of the first coil, the second coil, and the third coil driven by the coil drive control device is 1 kHz to 10 kHz.

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