Preparation method of water-soluble vitamin D2

A technology of water-soluble vitamins and vitamins, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, additional food elements, etc., can solve problems such as undiscovered data

CN114230499APending Publication Date: 2022-03-25SICHUAN NEIJIANG HUIXIN PHARMA
1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
Publication Date
2022-03-25
Patent Text Reader

Abstract

The invention discloses a preparation method of water-soluble vitamin D2, which comprises the following steps: preparing emulsion of vitamin D2, heating and dissolving macromolecular substances or synthetic biodegradable macromolecular substances in water, adding an emulsifier lauryl sodium sulfate, and uniformly stirring to obtain emulsion of a vitamin D2 carrier preparation; and adjusting the temperature of the emulsion of the vitamin D2 carrier preparation to 56-64 DEG C, adding the emulsion of the vitamin D2, and fully and uniformly stirring to obtain the mixed emulsion of the vitamin D2. By adopting the method disclosed by the invention, fat-soluble vitamin D2 can be prepared into water-soluble vitamin D2 which can be dissolved in water in any required proportion, and the water-soluble vitamin D2 can be prepared into liquid, powder, capsules or tablets, so that the application requirements of the fields of medicines, foods, feeds and the like on vitamin D can be met.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to vitamin D 2 Technical field, more specifically a water-soluble vitamin D 2 method of preparation. Background technique

[0002] Vitamin D 2 It is one of the trace organic compounds necessary for humans and animals to maintain normal life activities and health. Vitamin D can be added in moderation in medicines, food and feed 2 To meet the regular intake of people or animals from the outside world. Vitamin D 2 is vitamin D found in plants 2 main natural form. (referring to Chinese patent 95118188.2). Vitamins are divided into two categories according to their solubility, namely fat-soluble vitamins (A, D, E, K), etc., or water-soluble vitamins (B, B, B, B2, folic acid, niacin, and vitamin C). (See Chapter 15 of "Medicinal Chemistry", 1. The classification of vitamins (Wang Shuxia, Department of Agriculture and Medicine, Central TV University)). due to vitamin D 2 It is insoluble in water but soluble in fat and f...

Examples

Embodiment Construction

[0015] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Those who do not indicate the specific conditions in the examples are carried out according to the conventional conditions or the conditions suggested by the manufacturer. The reagents or instruments used were not indicated by the manufacturer, and they were all conventional products that could be purchased from the market.

[0016] The technical solutions of the present invention will be further limited below in conjunction with specific embodiments, but the scope of protection is not limited to the descriptions made.

[0017] The invention provides a technical solution: a water-soluble vitamin D 2 The preparation method comprises the following steps:

[0018] a. Dissolve the emulsifier in ethanol, then add vitamin D 2 , of which vitami...