Microfluidic detection system for refrigerator and refrigerator

Abstract

The present invention relates to a microfluidic detection system for a refrigerator and a refrigerator. The microfluidic detection system includes: a microfluidic biochip having an inlet and a communication port, and a detection pool formed therein, wherein the inlet, the detection pool, and the communication port are sequentially connected via a microfluidic channel to allow a sample liquid contacting the inlet to enter the detection pool via the inlet and the microfluidic channel; a chip mounting mechanism for detachably mounting the microfluidic biochip thereon; and a detection mechanism for detecting the detection pool to obtain preset detection parameters of the sample liquid. Thus, the system not only provides a stable support for the microfluidic biochip, but also ensures the detachability of the microfluidic biochip, making it convenient for users to install, remove, or replace the microfluidic biochip according to actual needs.

Description

Technical Field

[0001] The present invention relates to refrigeration and freezing technology, and in particular to a microfluidic detection system for a refrigerator and the refrigerator. Background Art

[0002] As people's living standards improve, they often need to test some of the food they eat for pesticide residues, viruses, nutrients, or other aspects in their daily lives to qualitatively or quantitatively determine the condition of the food. For example, due to the overuse of pesticides, the fruits, vegetables, and agricultural and sideline products we buy daily may contain excessive levels of pesticide residues. If these excessive levels of pesticide residues are not detected in a timely manner, they can cause great harm to the human body after ingestion. For another example, breastfeeding, which is currently advocated, is the best way to feed babies only when breast milk has normal nutritional value. However, if a nursing mother is ill, taking medication, undergoing surgery, or in other circumstances, the nutrient content of her milk may decrease or even contain viruses, thereby affecting the growth, development, and health of the baby.

[0003] Among the many detection methods, the method of using microfluidic biochips for detection is relatively fast, small in size, and suitable for home use. When the detection system is used for different detection purposes, the types of microfluidic biochips used are usually different. In addition, some microfluidic biochips are disposable and cannot be reused. Existing detection systems are usually independent, so the operation of replacing microfluidic biochips is not restricted by many aspects such as space, position and tools. However, the applicant realizes that the independent detection system takes up space and is not convenient for storage. After the detection device is stored, it may be forgotten to use it, or it may be too troublesome to take it out for use. For this reason, the applicant thought of integrating the detection system into the refrigerator. At this time, the refrigerator as a carrier will impose many restrictions on the disassembly and assembly operations of the microfluidic biochip in terms of space, position, etc. Therefore, the disassembly and assembly structure design of the microfluidic biochip is crucial and the design difficulty is relatively high. Summary of the Invention

[0004] One object of the first aspect of the present invention is to overcome at least one drawback of the prior art and to provide a microfluidic detection system suitable for a refrigerator that facilitates assembly and disassembly of a microfluidic biochip.

[0005] A further object of the first aspect of the present invention is to simplify the structure of the microfluidic detection system so as to make it more suitable for refrigerators.

[0006] Another further object of the first aspect of the present invention is to further improve the convenience of disassembly of the microfluidic biochip.

[0007] The second aspect of the present invention aims to provide a refrigerator having the above-mentioned microfluidic detection system.

[0008] According to a first aspect of the present invention, the present invention provides a microfluidic detection system for a refrigerator, comprising:

[0009] A microfluidic biochip having an inlet, a communication port, and a detection cell formed therein, wherein the inlet, the detection cell, and the communication port are sequentially connected via a microfluidic channel to allow a sample liquid contacting the inlet to sequentially enter the detection cell via the inlet and the microfluidic channel;

[0010] a chip mounting mechanism, for allowing the microfluidic biochip to be detachably mounted thereon; and

[0011] The detection mechanism is used to detect the detection pool to obtain preset detection parameters of the sample liquid.

[0012] Optionally, the chip mounting mechanism includes two elastic clamps arranged opposite to each other to apply opposite forces to the microfluidic biochip located between the two elastic clamps, so that the microfluidic biochip is clamped between the two elastic clamps.

[0013] Optionally, the microfluidic detection system further includes:

[0014] The chip ejection mechanism is configured to operably apply forces in opposite directions to the two elastic clamps to cause the two elastic clamps to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip.

[0015] Optionally, the chip ejection mechanism includes a cantilever button suspended on one side of the microfluidic biochip, and the cantilever button simultaneously abuts against the inner sides of the two elastic clamps that are arranged opposite to each other, so as to apply an outward force to the inner sides of the two elastic clamps when the cantilever button is subjected to a force toward the microfluidic biochip, thereby causing the two elastic clamps to elastically deform in outward directions away from each other.

[0016] Optionally, the cantilever button includes a button block and an abutment block protruding and extending from the inner side of the button block toward the microfluidic biochip in a direction gradually approaching the microfluidic biochip, and the two opposite side surfaces of the abutment block, which respectively abut against the inner sides of the two elastic clamps, are inclined toward each other in a direction gradually approaching the microfluidic biochip.

[0017] Optionally, the microfluidic biochip is vertically clamped between the two elastic clamping jaws; and

[0018] The two elastic clamps are respectively located on the lateral sides of the microfluidic biochip, and the cantilever button is suspended on the front side of the microfluidic biochip so as to prompt the two elastic clamps to move away from each other in the lateral direction when it is subjected to a backward force, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip and allowing the microfluidic biochip to fall under the action of its own gravity.

[0019] Optionally, a guide surface is provided on the inner side of the end of each of the two elastic clamps, and the two guide surfaces extend obliquely toward each other along the installation direction of the microfluidic biochip to guide the microfluidic biochip to be installed between the two elastic clamps along its installation direction.

[0020] Optionally, the microfluidic detection system further includes:

[0021] a sample liquid driving device, connected to the communication port and used to force the sample liquid in contact with the sample inlet to enter the microfluidic channel and flow toward the detection cell through the microfluidic channel; and

[0022] A sealing docking mechanism is used to form a fluid-tight connection between the microfluidic biochip and the sample liquid driving device.

[0023] Optionally, the microfluidic detection system further includes:

[0024] A sample stage is provided below the microfluidic biochip for placing a sample cup, wherein the sample cup is used to hold a sample liquid; and

[0025] The sample stage is configured to move in a controlled or operative manner so as to transport the sample cup placed thereon to a position where the sample liquid in the sample cup is allowed to contact the sample inlet of the microfluidic biochip.

[0026] Optionally, the pesticide residue detection system further includes:

[0027] The sample table is used to place a sample cup, and the sample cup is used to hold the sample liquid; wherein

[0028] The sample stage includes a support platform for supporting a sample cup and an oscillator arranged on the support platform. The oscillator is used to oscillate the sample cup after the sample cup is placed on the support platform, so that the buffer solution and the sample in the sample cup are fully mixed to produce the sample liquid.

[0029] According to a second aspect of the present invention, the present invention further provides a refrigerator comprising the microfluidic detection system according to any one of the above embodiments.

[0030] The microfluidic detection system of the present invention includes a microfluidic biochip that can provide a detection environment and detection conditions for a sample liquid and a detection mechanism for implementing detection operations. The microfluidic biochip is detachably mounted on the chip mounting mechanism, thereby ensuring the detachability of the microfluidic biochip and facilitating the user to install, disassemble or replace the microfluidic biochip according to actual needs.

[0031] Furthermore, the chip mounting mechanism includes two opposing elastic clamps that apply opposing forces to the microfluidic biochip located therebetween, thereby clamping the microfluidic biochip between the two clamps. The design of the two elastic clamps is very simple, taking up little space, and the elastic deformation of the clamps facilitates installation and removal of the microfluidic biochip. This makes the microfluidic detection system more suitable for refrigerator integration, both in terms of structure and operation, without complicating the refrigerator structure or hindering user access to the chip.

[0032] Furthermore, the microfluidic detection system also includes a chip ejection mechanism, which allows a user to apply opposing forces to the two elastic clamping jaws, causing them to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamping jaws on the microfluidic biochip, allowing the microfluidic biochip to be easily removed. The above and other objects, advantages, and features of the present invention will become more apparent to those skilled in the art based on the detailed description of specific embodiments of the present invention described below in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Hereinafter, some specific embodiments of the present invention will be described in detail in an exemplary and non-limiting manner with reference to the accompanying drawings. The same reference numerals in the accompanying drawings indicate the same or similar components or parts. It should be understood by those skilled in the art that these drawings are not necessarily drawn to scale. In the accompanying drawings:

[0034] Figure 1 is a schematic structural diagram of a microfluidic detection system for a refrigerator according to one embodiment of the present invention;

[0035] Figure 2 is a schematic structural exploded diagram of a microfluidic detection system for a refrigerator according to one embodiment of the present invention;

[0036] Figure 3 is a schematic structural diagram of the internal structure of a microfluidic detection system according to one embodiment of the present invention;

[0037] Figure 4 is a schematic structural exploded diagram of the internal structure of a microfluidic detection system according to one embodiment of the present invention;

[0038] Figure 5is a schematic structural diagram of a microfluidic biochip according to one embodiment of the present invention;

[0039] Figure 6 is a schematic structural diagram of a microfluidic biochip, a chip mounting mechanism, and a chip ejection mechanism according to one embodiment of the present invention;

[0040] Figure 7 is a schematic structural exploded view of a microfluidic biochip, a chip mounting mechanism, and a chip ejection mechanism according to one embodiment of the present invention;

[0041] Figure 8 is a schematic structural exploded view of a microfluidic biochip, a chip mounting mechanism, a sample liquid driving device, and a sealing docking structure according to one embodiment of the present invention;

[0042] Figure 9 is a schematic structural diagram of a lifting mechanism and a sample stage in a disassembled state according to one embodiment of the present invention;

[0043] Figure 10 is a schematic structural diagram of a refrigerator according to one embodiment of the present invention;

[0044] Figure 11 1 is a schematic structural exploded view of a door body according to one embodiment of the present invention. DETAILED DESCRIPTION

[0045] The present invention first provides a microfluidic detection system for a refrigerator. The microfluidic detection system of the present invention is used to perform qualitative or quantitative detection on preset detection parameters of a sample liquid. The preset detection parameters can, for example, be a pesticide residue parameter used to indicate whether the pesticide residue exceeds the standard and / or the specific value of the pesticide residue, a nutritional parameter used to indicate whether a nutrient element meets the standard and / or the specific content of the nutrient element, a specific substance parameter used to indicate whether a specific harmful substance (such as a specific virus) exceeds the standard and / or the specific content, and the like.

[0046] Figure 1 is a schematic structural diagram of a microfluidic detection system for a refrigerator according to one embodiment of the present invention. Figure 2 is a schematic structural exploded view of a microfluidic detection system for a refrigerator according to one embodiment of the present invention. Figure 3 is a schematic structural diagram of the internal structure of a microfluidic detection system according to one embodiment of the present invention, Figure 4 : is a schematic structural decomposition diagram of the internal structure of a microfluidic detection system according to an embodiment of the present invention. For ease of understanding, Figures 1 to 4 A sample cup 2 is also shown.

[0047] See also Figures 1 to 4The microfluidic detection system 1 of the present invention includes a microfluidic biochip 10, a chip mounting mechanism 51, and a detection mechanism 20. Those skilled in the art will appreciate that when the microfluidic detection system is used to detect different preset detection parameters, the specific selection of the microfluidic biochip 10 and detection mechanism 20 used therein may also vary. For example, when the microfluidic detection system is used for pesticide residue detection, the microfluidic biochip 10 it possesses can be a microfluidic pesticide residue detection chip capable of providing detection conditions for pesticide residue liquid, and the detection mechanism 20 it possesses can be a pesticide residue detection mechanism capable of detecting pesticide residue parameters in the pesticide residue liquid.

[0048] Figure 5 1 is a schematic structural diagram of a microfluidic biochip according to an embodiment of the present invention. The microfluidic biochip 10 has an injection port 111, a communication port 112, and a detection pool 121 formed therein. The injection port 111, the detection pool 121, and the communication port 112 are sequentially connected through a microchannel 14, allowing the sample liquid in contact with the injection port 111 to enter the detection pool 121 through the injection port 111 and the microchannel 14 in sequence. The injection port 111, the detection pool 121, and the communication port 112 are sequentially connected to form a main channel. The microchannel involved in the present invention refers to a fine flow channel or capillary flow channel with a flow area within a preset size range so that it has the appropriate ability to retain the liquid therein. The injection port 111 and the communication port 112 can be formed at the ends of the microfluidic biochip 10. Furthermore, the injection port 111 and the communication port 112 are preferably formed at different ends of the microfluidic biochip 10.

[0049] The chip mounting mechanism 51 is used for the microfluidic biochip 10 to be detachably mounted thereon, so as to facilitate the disassembly of the microfluidic biochip 10 .

[0050] The detection mechanism 20 is used to test the detection pool 121 to obtain preset detection parameters of the sample liquid. Specifically, the detection pool 121 may be pre-installed with a detection reagent, or the detection reagent may be added to the detection pool 121 manually or automatically. After the sample liquid in the detection pool 121 reacts with the detection reagent therein, the detection pool 121 is tested by the detection mechanism 20.

[0051] In a specific embodiment, when the detection mechanism 20 is a pesticide residue detection mechanism for detecting pesticide residue parameters in a pesticide residue liquid, an enzyme inhibition rate method can be used to quickly qualitatively detect whether the pesticide residue in the sample liquid exceeds the standard. In this case, the microfluidic biochip 10 also includes a reaction pool 122 formed therein. The reaction pool 122 is located on a main channel formed by the injection port 111, the detection cell 121, and the communication port 112 connected in sequence, and is connected between the injection port 111 and the detection cell 121, so that the sample liquid first reacts with the reaction reagent in the reaction pool 122 before flowing into the detection cell 121. The reaction pool 122 and the injection port 111, as well as the reaction pool 122 and the detection cell 121, are connected by microchannels 14. The reaction reagent and detection reagent used for pesticide residue detection can be an enzyme reagent and a color developer, respectively. The reaction pool 122 is used for the sample liquid to react with the enzyme reagent therein. The sample liquid after reacting with the enzyme reagent flows into the detection cell 121 and reacts with the color developer in the detection cell 121. The detection mechanism 20 can be selected as a photoelectric detection mechanism, which can include a light source 21 and a photosensitive element 22 respectively arranged on two opposite sides of the microfluidic biochip 10 and both facing the detection pool 121. The light emitted by the light source 21 is irradiated to the detection pool 121, and the light passing through the detection pool 121 is introduced into the photosensitive element 22, thereby facilitating the determination of the absorbance change in the detection pool 121 through the light intensity signal received by the photosensitive element 22, and then calculating the pesticide residue inhibition rate. Furthermore, the detection mechanism 20 also includes a heating plate 24 for providing heat to the detection pool 121 and a temperature controller 25 for controlling the heating power of the heating plate 24 to be constant, so that the sample liquid and the detection reagent in the detection pool 121 react fully and quickly.

[0052] The microfluidic detection system 1 of the present invention includes a microfluidic biochip 10 that can provide a detection environment and detection conditions for a sample liquid and a detection mechanism 20 for implementing detection operations. The microfluidic biochip 10 is detachably mounted on a chip mounting mechanism 51, thereby ensuring the detachability of the microfluidic biochip 10 and facilitating the user to install, disassemble or replace the microfluidic biochip 10 according to actual needs.

[0053] Figure 6 is a schematic structural diagram of a microfluidic biochip, a chip mounting mechanism, and a chip ejection mechanism according to an embodiment of the present invention. Figure 7This is a schematic exploded view of the microfluidic biochip, chip mounting mechanism, and chip ejection mechanism according to one embodiment of the present invention. In some embodiments, the chip mounting mechanism 51 includes two opposing elastic clamps 511 that apply opposing forces to the microfluidic biochip 10 positioned between the two elastic clamps 511, thereby clamping the microfluidic biochip 10 between the two elastic clamps 511. In other words, both elastic clamps 511 apply an inward elastic force to the microfluidic biochip 10, maintaining a secure grip for extended periods of time.

[0054] The design structure of the two elastic clamps 511 is very simple and occupies little space. The installation and disassembly operations of the microfluidic biochip 10 can be easily implemented through the elastic deformation of the elastic clamps 511. Therefore, in terms of both structure and use, the microfluidic detection system 1 is more suitable for integration in the refrigerator, without causing the refrigerator structure to be complicated, and without affecting the user's operation of disassembling and installing the chip in the refrigerator.

[0055] Furthermore, the chip mounting mechanism 51 further includes a mounting plate 512 fixedly disposed within the housing 80 of the microfluidic detection system 1, and two elastic clamping jaws 511 protrude outward from the edge of the mounting plate 512. Specifically, the mounting plate 512 can be fixed to a bracket 87, which is fixedly disposed within the housing 80.

[0056] In some embodiments, a guide surface 5111 may be provided on the inner side of the end of each of the two elastic clamps 511. The two guide surfaces 5111 extend toward each other at an angle along the installation direction of the microfluidic biochip 10 to guide the microfluidic biochip 10 to be installed between the two elastic clamps 511 along its installation direction, thereby improving the smoothness of the installation of the microfluidic biochip 10 and avoiding large resistance or jamming during installation.

[0057] Specifically, the microfluidic biochip 10 can be installed vertically from bottom to top on the chip mounting mechanism 51, and the guide surface 5111 can be located on the inner side of the bottom of the elastic clamp 511. The guide surfaces 5111 of the two elastic clamps 511 extend toward each other from bottom to top to guide the installation of the microfluidic biochip 10.

[0058] Since the microfluidic detection system 1 is integrated into a refrigerator with a relatively small operating space, the disassembly operation of the microfluidic biochip 10 basically cannot be performed directly on the chip mounting mechanism 51 .

[0059] To this end, in some embodiments, the microfluidic detection system 1 of the present application is also specially designed with a chip ejection mechanism 52, which is configured to operably apply forces in opposite directions to the two elastic clamping jaws 511, so as to cause the two elastic clamping jaws 511 to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamping jaws 511 on the microfluidic biochip 10. In other words, the user can apply opposite forces to the two elastic clamping jaws 511 through the chip ejection mechanism 52, causing the two elastic clamping jaws 511 to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamping jaws 511 on the microfluidic biochip 10, releasing the microfluidic biochip 10, and the microfluidic biochip 10 can be easily disassembled.

[0060] Preferably, the chip ejection mechanism 52 can be exposed on the outside of the microfluidic detection system 1 to facilitate the user to perform the chip ejection operation. No matter how compact the structural layout of the microfluidic detection system 1 itself and its overall structural layout after integration into the refrigerator are, it will not affect the disassembly operation of the microfluidic biochip 10, thereby improving the user experience.

[0061] In some embodiments, the chip ejection mechanism 52 may include a cantilever button 521 suspended from one side of the microfluidic biochip 10. The cantilever button 521 simultaneously abuts against the inner sides of the two elastic clamping jaws 511 disposed opposite each other, so that when the cantilever button 521 is subjected to a force acting toward the microfluidic biochip 10, an outward force is applied to the inner sides of the two elastic clamping jaws 511, thereby causing the two elastic clamping jaws 511 to elastically deform in directions away from each other. In other words, when the microfluidic biochip 10 needs to be disassembled, the user only needs to press the cantilever button 521 to release the clamping effect of the two elastic clamping jaws 511 on the microfluidic biochip 10, thereby releasing the microfluidic biochip 10. The operation is very simple, and the chip ejection mechanism 52 has a very simple structure and a very clever design.

[0062] Furthermore, the chip ejection mechanism 52 may further include a cantilever arm 522 connected between the cantilever button 521 and the mounting plate 512. The cantilever arm 522 may extend vertically outward from one side of the mounting plate 512 for a certain distance, then bend in a direction parallel to the mounting plate 512 and extend to connect with the cantilever button 521. This provides a certain amount of displacement space and return space for the cantilever button 521. The position of the cantilever button 521 may correspond to the position where the elastic clamping jaw 511 contacts the microfluidic biochip 10.

[0063] In some embodiments, the cantilever button 521 may include a button block 5211 and an abutment block 5212 that protrudes from the button block 5211 toward the inner side of the microfluidic biochip 10 and gradually approaches the microfluidic biochip 10. The two opposing side surfaces of the abutment block 5212, which respectively abut against the inner sides of the two elastic clamping jaws 511, are inclined toward each other in a direction gradually approaching the microfluidic biochip 10 to ensure smooth pressing of the cantilever button 521 and avoid the occurrence of jamming. Specifically, the abutment block 5212 may be roughly in the shape of an isosceles trapezoid, with the lower base of the isosceles trapezoid connected to the button block 5211 and the two waists of the isosceles trapezoid respectively abutting against the inner sides of the two elastic clamping jaws 511.

[0064] In some embodiments, the microfluidic biochip 10 is vertically clamped between two elastic clamps 511, that is, the microfluidic biochip 10 is placed vertically. The two elastic clamps 511 are located on either side of the microfluidic biochip 10, and the cantilever button 521 is suspended from the front side of the microfluidic biochip 10. When the cantilever button 521 is subjected to a backward force, it causes the two elastic clamps 511 to move laterally away from each other, thereby releasing the clamping effect of the two elastic clamps 511 on the microfluidic biochip 10 and allowing the microfluidic biochip 10 to fall under its own weight. This configuration allows the microfluidic biochip 10 to automatically fall under its own weight after the clamping effect of the two elastic clamps 511 is released, eliminating the need for the user to manually remove the chip and preventing it from being contaminated by liquid on the microfluidic biochip 10.

[0065] In some embodiments, the sample liquid in contact with the injection port 111 can flow into the microchannel 14 and the detection pool 121 under the driving action of the pressure difference generated by the main channel and the atmosphere, or can flow into the microchannel 14 and the detection pool 121 under the capillary suction of the microchannel 14. At this time, the microchannel 14 can be designed to enable the liquid in the detection pool 121 and the microchannel 14 to overcome its own gravity and remain in the detection pool 121 and the microchannel 14 when the microfluidic biochip 10 is placed vertically and the injection port 111 is at its bottom.

[0066] In some preferred embodiments, the sample liquid in contact with the sample inlet 111 can flow into the microchannel and the detection cell under the driving action of the driving mechanism. For example, in one embodiment, the microfluidic detection system 1 further includes a sample liquid driving device 40 and a sealing docking mechanism 90. The sample liquid driving device 40 is in communication with the communication port 112 and is used to force the sample liquid in contact with the sample inlet 111 into the microchannel and then flow through the microchannel to the detection cell 121. Specifically, the sample liquid driving device 40 can create a negative pressure within the main channel by sucking air outward, thereby allowing the sample liquid in contact with the sample inlet 111 to flow into the microchannel under the action of the negative pressure. The sealing docking mechanism 90 is used to form a fluid-tight connection between the microfluidic biochip 10 and the sample liquid driving device 40, thereby preventing problems such as air leakage or liquid leakage at the connection between the two that could affect the pressure within the main channel and, in turn, affect the entry of the sample liquid into the main channel. This ensures normal sampling performance of the microfluidic detection system 1 and facilitates precise control of the sampling process using the sample liquid driving device 40.

[0067] Figure 8 1 is a schematic structural exploded view of a microfluidic biochip, a chip mounting mechanism, a sample liquid driving device, and a sealed docking structure according to an embodiment of the present invention. In some embodiments, the sealed docking mechanism 90 may include a sealing connector 91 and an elastic pressure member 92. The sealing connector 91 is connected between the microfluidic biochip 10 and the sample liquid driving device 40, and a connecting channel is formed therein that passes through the sealing connector 91. The elastic pressure member 92 is used to apply an elastic force to the sealing connector 91 so that the sealing connector 91 is sealed and docked with the sample liquid driving device 40 and the microfluidic biochip 10 at the same time, thereby allowing the sample liquid driving device 40 and the communication port 112 of the microfluidic biochip 10 to be sealed and connected through the connecting channel inside the sealing connector 91. Thus, an elastic force can be applied to the sealing connector 91 by the elastic pressure member 92, so as to urge the sealing connector 91 to always maintain a tightly sealed docking state with the sample liquid driving device 40 and the microfluidic biochip 10 at the same time, avoiding the problems of loosening, breaking, etc. after long-term use caused by adopting other docking mechanisms, thereby ensuring a long-term and reliable fluid sealing connection relationship between the sample liquid driving device 40 and the connecting port 112 of the microfluidic biochip 10, and improving the sealing effect between the two.

[0068] In some embodiments, an elastic pressure member 92 is disposed between the sealing connector 91 and the sample liquid driving device 40 to apply an elastic force to the sealing connector 91 toward the microfluidic biochip 10. This elastic force thereby causes the sealing connector 91 and the microfluidic biochip 10 to elastically abut tightly against each other, and the reaction force exerted by the microfluidic biochip 10 on the sealing connector 91 causes the sealing connector 91 to elastically and sealedly dock with the sample liquid driving device 40. It is understood that in some alternative embodiments, the elastic pressure member 92 may also be disposed between the sealing connector 91 and the microfluidic biochip 10. The principle of its operation is the same as in the above embodiment and will not be further described here.

[0069] In some embodiments, the sample liquid driving device 40 is connected to the communication port 112 via a connecting pipe 46. The communication port 112 can be formed at the top of the microfluidic biochip 10, and the sample liquid driving device 40 can be positioned adjacent to the microfluidic biochip 10 in a lateral direction to prevent potential leakage from the microfluidic biochip 10 from adversely affecting the sample liquid driving device 40. The connecting pipe 46 can be connected to the top of the sample liquid driving device 40 to bridge the gap between the sample liquid driving device 40 and the microfluidic biochip 10.

[0070] Furthermore, the sealing connector 91 includes a first connecting post 911 that protrudes and extends toward the connecting conduit 46. The connecting passage within the sealing connector 91 extends through the first connecting post 911. The first connecting post 911 is inserted into the connecting conduit 46 and tightly contacts the inner wall of the connecting conduit 46, thereby sealingly connecting the connecting passage within the sealing connector 91 with the connecting conduit 46 and, consequently, with the sample liquid driving device 40. In other words, the first connecting post 911 and the connecting conduit 46 are sleeved together. This sleeved connection increases the contact surface area between the two, thereby improving the sealing performance of the connection.

[0071] In some embodiments, the elastic pressure member 92 can be a spring, one end of which abuts against a fixed end plate 513, and the other end abuts against the sealing connector 91, and the end plate 513 and the microfluidic biochip 10 are respectively located on opposite sides of the sealing connector 91. Specifically, the end plate 513 can extend horizontally perpendicular to the mounting plate 512 of the chip mounting mechanism 51. When the microfluidic biochip 10 is in the installed state, the spring is in a compressed state, thereby generating an elastic force for causing the sealing connector 91 to have a tendency to move toward the microfluidic biochip 10. The number of elastic pressure members 92 can be two or more, so as to increase the magnitude of the elastic force acting on the microfluidic biochip 10, and make the elastic force on the microfluidic biochip 10 more balanced, avoid tilting, and further improve the effect of the sealing connection.

[0072] Furthermore, the sealed docking mechanism 90 includes a guide rod 93, on which a spring is mounted to prevent displacement. One end of the guide rod 93 is fixedly connected to the sealing connector 91, and the other end contacts a Hall switch 94 after the microfluidic biochip 10 is sealedly docked with the sealing connector 91. This causes the Hall switch 94 to generate a trigger signal indicating that the microfluidic biochip 10 is properly installed, thereby notifying the user. This prevents structural damage to the microfluidic biochip 10 caused by over-installation and improves the user experience.

[0073] In some embodiments, the sealing connector 91 further includes a first connecting block 912 for directly docking with the microfluidic biochip 10 and a second connecting block 913 disposed on the side of the first connecting block 912 facing away from the microfluidic biochip 10. The first connecting post 911 protrudes from the second connecting block 913 toward the connecting pipe 46. The second connecting block 913 has a post hole formed therein. The side of the first connecting block 912 facing away from the microfluidic biochip 10 has a second connecting post 914 formed therein. The second connecting post 914 is inserted into the post hole. The connecting channel within the sealing connector 91 passes through the first connecting post 911, the first connecting block 912, and the second connecting block 913. Thus, a sleeve-type connection is formed between the first connecting block 912 and the second connecting block 913, which increases the contact area between the two and improves the sealing performance of the connection between the two.

[0074] In some embodiments, the sample liquid driving device 40 may include a drive motor 41, which is suspended in the air, and the top of the drive motor 41 is fixed to a bracket 87 to support the drive motor 41. In other words, the drive motor 41 is supported by the bracket 87 fixedly connected to its top, and the drive motor 41 does not contact other structures, thereby preventing the vibration generated by the drive motor 41 during operation from being transmitted to the microfluidic biochip 10 or other structures. This not only prevents adverse effects on the stability or performance of the microfluidic biochip 10 or other structures, but also reduces the vibration of the entire microfluidic detection system 1 and reduces its operating noise. In addition, since the drive motor 41 is used frequently and generates a lot of heat, the suspended arrangement of the drive motor 41 also increases the space around it, which is conducive to heat dissipation.

[0075] Furthermore, the sample liquid driving device 40 can form a negative pressure in the main channel by pumping air outward, so that the sample liquid in contact with the injection port 111 enters the main channel under the action of the negative pressure. Specifically, the sample liquid driving device 40 can be a micro-injection pump, and also includes a vertically extending syringe 42, a screw rod 43, a slider 44 and a piston. The syringe 42 is fixed on the bracket 87, and the top of the syringe 42 is sealed and connected to the connecting port 112 at the top of the microfluidic biochip 10 through the connecting pipe 46. The screw rod 43 extends vertically and is connected to the drive motor 41 so as to rotate under the drive of the drive motor 41. The slider 44 is passed through the screw rod 43 and is threadedly connected to the screw rod 43 so as to translate up and down along the screw rod 43 as the screw rod 43 rotates. The piston is arranged inside the syringe 42 and is fixedly connected to the slider 44 so as to be translated in the up and down directions under the drive of the slider 44. When it translates downward, a negative pressure is generated in the main channel, thereby prompting the sample liquid in contact with the injection port 111 to flow into the microchannel 14 and into the detection pool 121 through the microchannel 14. When it translates upward, it prompts the sample liquid in the main channel to flow toward the injection port 111.

[0076] In some embodiments, the microfluidic detection system 1 further includes a sample stage 70 disposed below the microfluidic biochip 10 for placing a sample cup 2 for holding a sample liquid. This allows the microfluidic biochip 10 to fall into the sample cup 2 under its own gravity and be removed along with the sample cup 2, preventing the user from contacting the microfluidic biochip 10.

[0077] Furthermore, the sample stage 70 is configured to move in a controlled or operable manner so as to transport the sample cup 2 placed thereon to a position that allows the sample liquid in the sample cup 2 to contact the sampling port 111 of the microfluidic biochip 10 through the sample stage 70. In this way, the loading of the microfluidic biochip 10 is achieved. The user only needs to place the sample cup 2 on the sample stage 70, or, after placing the sample cup 2 on the sample stage 70, move the sample stage 70 to a position that contacts the sampling port 111 of the microfluidic biochip 10. The loading operation is very convenient, saving time and effort. In addition, the present application eliminates complex structures such as the sample liquid delivery pump, delivery pipeline, and sampling needle by setting the sample stage 70 to be movable, making the structure of the microfluidic detection system 1 very simple, thereby making it suitable for integration into a refrigerator for easy home use.

[0078] Furthermore, the microfluidic detection system 1 includes a lifting mechanism 60 for driving the sample stage 70 to move up and down, so that the sample stage 70 can switch between a detection position in which the sample liquid in the sample cup 2 placed on the sample stage 70 contacts the injection port 111, and an initial position at a predetermined distance below the detection position. In other words, the sample stage 70 can be automatically raised and lowered by the lifting mechanism 60.

[0079] Figure 9 : is a schematic structural diagram of a lifting mechanism and a sample stage in a disassembled state according to an embodiment of the present invention. In some embodiments, the lifting mechanism 60 may include a lifting motor 61, a transmission screw 62 and a nut 63. The lifting motor 61 is used to output a driving force. The transmission screw 62 is arranged in a vertical direction and is connected to the output shaft of the lifting motor 61 so as to rotate under the drive of the lifting motor 61. The nut 63 is passed through the transmission screw 62 and is threadedly connected to the transmission screw 62 so as to move up and down along the transmission screw 62 as the transmission screw 62 rotates. The sample stage 70 is fixedly connected to the nut 63 to drive the sample stage 70 to move up and down through the nut 63.

[0080] Furthermore, the lifting mechanism 60 also includes a slide rail 64 and a slider 65. The slide rail 64 is arranged parallel to the transmission screw 62 and is arranged beside the transmission screw 62. The slider 65 is movably arranged on the slide rail 64. The sample stage 70 is fixedly connected to the slider 65 so as to guide the sample stage 70 to move up and down through the cooperation of the slide rail 64 and the slider 65. Specifically, when the sample stage 70 moves in the up and down directions under the action of the drive module, it drives the slider 65 to move synchronously. The slider 65 is restricted on the slide rail 64. The slide rail 64 has a guiding and limiting effect on the movement of the slider 65, thereby indirectly guiding and limiting the sample stage 70, avoiding the sample stage 70 from deflecting or jamming during movement, and improving the smoothness of the movement of the sample stage 70. Specifically, the sample stage 70 may include a horizontal connecting plate 74 that passes through the transmission screw 62 and is fixedly connected to the nut 63, and a vertical connecting plate 75 that extends upward perpendicular to the horizontal connecting plate 74. The vertical connecting plate 75 is fixedly connected to the slider 65.

[0081] In some embodiments, the lifting mechanism 60 further includes a limit switch 66, which is disposed adjacent to the upper portion of the transmission screw 62 to cause the lifting motor 61 to stop running when the sample stage 70 moves upward and touches the limit switch 66. Furthermore, the position of the limit switch 66 is configured so that when the lifting motor 61 stops running under the triggering of the limit switch 66, the sample stage 70 is in its detection position. The lifting motor 61 can maintain the sample stage 70 in its detection position when it is not running. The present application uses the limit switch 66 to locate the detection position of the sample stage 70, and the positioning is precise, which can avoid the problem that the sample stage 70 continues to move beyond its detection position, causing damage to the sample stage 70, the microfluidic biochip 10, and other structures.

[0082] In some embodiments, the sample stage 70 may include a support platform 71 and an oscillator 72. The support platform 71 is used to support the sample cup 2. Specifically, the support platform 71 may be a horizontal support plate. The support plate may be provided with a groove for the bottom of the sample cup 2 to rest within. This prevents the sample cup 2 from tipping or shaking during movement of the sample stage 70, thereby improving the stability of the sample cup 2. The support platform 71 is fixedly connected to a horizontal connecting plate 74.

[0083] An oscillator 72 is mounted on the support 71 and is used to oscillate the sample cup 2 after it is placed on the support 71. This allows the buffer solution in the sample cup 2 to mix thoroughly with the sample, thereby producing a sample solution. This allows the substance to be detected in the sample to be fully dissolved in the buffer solution, resulting in a sample solution of appropriate concentration. The buffer solution can be manually added to the sample cup 2 or automatically delivered to the sample cup 2 by a drive device after the sample cup 2 is placed on the sample stage 70.

[0084] In some embodiments, the sample stage 70 further includes a weighing sensor 73, which is positioned below the support platform 71 and is used to measure the weight of the sample in the sample cup 2, thereby allowing the buffer drive device 30 to deliver a preset amount of buffer that matches the sample weight to the sample cup 2. Typically, home users extract samples more casually, such as casually tearing off a small piece of vegetable leaf. Therefore, to ensure the accuracy of the measurement results, the amount of buffer input into the sample cup 2 needs to match the amount of the sample, so that a sample solution of appropriate concentration can be produced. The present application utilizes the weighing sensor 73 positioned below the support platform 71 to automatically and accurately obtain the sample weight, thereby automatically controlling the buffer drive device 30 to input a matching amount of buffer into the sample cup 2. This ensures the accuracy of the measurement results while avoiding the many problems associated with manual weighing of the sample, such as inconvenience, cumbersome operation, and large errors, further improving the automation level of the microfluidic detection system and the user experience.

[0085] It should be noted that, in some alternative embodiments, the sample stage 70 may be fixed, and the microfluidic biochip 10 may be movable, which can also facilitate the sampling operation.

[0086] In some embodiments, the microfluidic detection system 1 further includes a housing 80. The housing 80 is formed with an operating table 83 open to its front side. The sample stage 70 is at least partially located within the operating table 83, facilitating operations such as placing and removing the sample cup 2 there. A water collection box 88 can be provided below the sample stage 70 within the operating table 83 to collect any dripping liquid and prevent contamination of the operating table 83. At least a portion of the microfluidic biochip 10, the detection mechanism 20, the chip mounting structure 51, and the chip ejection mechanism 52 are all disposed within the housing 80. Furthermore, the housing 80 is provided with a first structural connector 81 for connecting to the refrigerator housing or door, and a first electrical connector 82 for establishing an electrical connection between the microfluidic detection system 1 and the electronic control device of the refrigerator 100, allowing the microfluidic detection system 1 to be integrally mounted to the refrigerator housing or door.

[0087] In some embodiments, the microfluidic detection system 1 further includes a buffer bottle 36 and a buffer drive device 30. The buffer bottle 36 is disposed within the housing 80 and is used to hold a buffer solution. The buffer drive device 30 is disposed within the housing 80 and communicates with the buffer bottle 36 to controllably drive the buffer solution within the buffer bottle 36 into the sample cup 2 placed on the sample stage 70, thereby mixing the buffer solution with the sample in the sample cup 2 to produce a sample solution. Specifically, the buffer bottle 36 and the buffer drive device 30 are connected via an inlet tube 32. The outlet tube 31 of the buffer drive device 30 extends to the sample stage 70. This is primarily useful when the sample being tested is a solid sample, requiring the use of a buffer solution to dissolve the substance to be tested in the solid sample to form a sample solution; or when the sample is a liquid sample with a high concentration, requiring dilution with a buffer solution to produce a sample solution. For example, in pesticide residue testing, the sample being tested is typically solid food scraps such as skin or leaves. The sample needs to be placed in a buffer solution, and the residual pesticide in the sample dissolves into the buffer solution to form a sample solution.

[0088] Specifically, the buffer drive device 30 can be a peristaltic pump, a diaphragm pump, or other suitable type of drive device. During operation, the peristaltic or diaphragm pump generates significant vibration in its radial direction. To prevent this vibration from being transmitted to the microfluidic biochip 10, an elastic vibration damper 35 can be provided radially outwardly of the peristaltic or diaphragm pump. The elastic vibration damper 35 can be mounted externally of the buffer drive device 30 and supported within the housing 80 by a bracket 87 and a fixing block 89. The fixing block 89 can be fixed to the support plate 86.

[0089] In some embodiments, the microfluidic detection system 1 further includes a circuit board 53, a display device 56 and a switch button 57. The circuit board 53 is disposed in the housing 80 and is electrically connected to the first electrical connector 82 on the housing 80. The electrical components of the microfluidic detection system 1 (such as the lifting mechanism 60, the buffer drive device 30, the sample liquid drive device 40, the display device 56, the switch button 57, etc.) are all electrically connected to the circuit board 53 directly or indirectly. The display device 56 is disposed on the front side of the housing 80 and is electrically connected to the circuit board 53 for displaying the detection results of the detection mechanism 20. The switch button 57 is disposed on the front side of the housing 80 and is electrically connected to the circuit board 53 for starting and / or shutting down the detection function of the microfluidic detection system 1. In other words, the user can start, pause or stop the detection function of the microfluidic detection system 1 by operating the switch button 57.

[0090] In some embodiments, the housing 80 may include a rear shell 84 at the rear side and a front panel 85 connected to the front side of the rear shell 84. When assembled, the rear shell 84 and the front panel 85 define a storage chamber therebetween. Furthermore, a support plate 86 and a bracket 87 are provided within the storage chamber of the housing 80. The support plate 86 is fixedly connected to the rear shell 84, and at least a portion of the structure of the lifting mechanism 60 (such as the non-movable portion of the lifting mechanism) and the buffer drive device 30 are fixed to the support plate 86. The bracket 87 is fixedly connected to the front side of the support plate 86, and the microfluidic biochip 10 and the sample liquid drive device 40 are directly or indirectly supported by the bracket 87. Thus, the support plate 86 and the bracket 87 can stably support the lifting mechanism 60, the buffer drive device 30, the microfluidic biochip 10, and the sample liquid drive device 40 within the storage chamber formed between the rear shell 84 and the front panel 85.

[0091] In some embodiments, the lifting mechanism 60 can be positioned laterally to the side of the sample stage 70, the buffer drive device 30 can be positioned on one side of the microfluidic biochip 10 and above the lifting mechanism 60, the sample liquid drive device 40 is positioned on the other side of the microfluidic biochip 10, and the buffer bottle 36 is positioned on the side of the sample liquid drive device 40 facing away from the microfluidic biochip 10. This arrangement of the microfluidic biochip 10, sample stage 70, lifting mechanism 60, buffer drive device 30, sample liquid drive device 40, and buffer bottle 36 fully utilizes the vertical and lateral dimensions of each module, making the layout of each module more compact and minimizing the space occupied. Furthermore, the modules are arranged side by side only in the vertical and lateral directions, minimizing the thickness of the microfluidic detection system 1 in the front-to-back direction, making it more suitable for integration into a refrigerator.

[0092] Furthermore, a transversely extending partition 861 may be provided between the buffer driving device 30 and the lifting mechanism 60 to prevent possible leakage of the buffer driving device 30 from dripping onto the lifting mechanism 60 and affecting the normal operation of the lifting mechanism 60. The partition 861 may be fixed to the support plate 86.

[0093] The present invention also provides a refrigerator. Figure 10 is a schematic structural diagram of a refrigerator according to one embodiment of the present invention. The refrigerator 100 of the present invention includes the microfluidic detection system 1 described in any of the above embodiments, with the microfluidic detection system 1 integrated into the refrigerator 100. Refrigerators 100 are frequently used in daily life and are primarily used to store food. When the microfluidic detection system 1 is integrated into the refrigerator 100, users can easily utilize the microfluidic detection system 1 to perform food sample testing operations.

[0094] Furthermore, the refrigerator 100 includes a housing 200 and a door 300. The housing 200 defines a storage space. The door 300 is connected to the housing 200 and is used to open and / or close the storage space. The microfluidic detection system 1 is preferably disposed on the door 300. This is not only convenient for operation, but also does not occupy the original storage space in the housing 200, thereby not affecting the storage capacity of the refrigerator 100 itself.

[0095] Figure 11 This is a schematic exploded view of the door structure according to one embodiment of the present invention. In some embodiments, the front side of the door 300 has a hollow window 301. The sample stage 70 of the microfluidic detection system 1 is exposed to the front side of the door 300 through the hollow window 301. This allows the user to place a sample cup on the sample stage 70 without having to open the door 300. This avoids the problem of severe cold leakage caused by opening the door 300 for each test, ensuring the heat preservation performance of the refrigerator 100 and saving energy.

[0096] Specifically, the door body 300 may include a panel 302 forming its front portion, a door lining 303 forming its rear portion, and a foamed insulation layer (not shown) disposed between the panel 302 and the door lining 303. A hollow window 301 is provided in the panel 302. Before the foamed insulation layer is formed, a pre-embedded box 304 is embedded between the panel 302 and the door lining 303. The microfluidic detection system 1 is disposed within the pre-embedded box 304. In other words, the pre-embedded box 304 is pre-installed between the panel 302 and the door lining 303 before the door body 300 is foamed, reserving space between the panel 302 and the door lining 303 for mounting the microfluidic detection system 1.

[0097] Furthermore, the embedded box 304 is attached to the rear surface of the panel 302, and the front side of the embedded box 304 is open and faces the hollow window 301, so as to allow the microfluidic detection system 1 to be installed into the embedded box 304 from front to back through the hollow window 301, thereby improving the convenience of installation of the microfluidic detection system 1.

[0098] Specifically, the embedded box 304 may be provided with a second structural connector 305 that mates with the first structural connector 81 and a second electrical connector 306 that is electrically connected to the first electrical connector 82. The second electrical connector 306 is electrically connected to the electronic control device of the refrigerator 100. Thus, by providing corresponding structural and electrical connectors on the embedded box 304 and the housing 80, the microfluidic detection system 1 is installed as a whole on the door 300, thereby achieving a connection between the entire microfluidic detection system 1 and the refrigerator 100 in terms of both structure and circuit. This not only simplifies the assembly process of the microfluidic detection system 1, but also facilitates disassembly or maintenance of the microfluidic detection system 1.

[0099] The refrigerator 100 of the present application is a refrigerator in a broad sense, which not only includes the so-called refrigerator in a narrow sense, but also includes storage devices with refrigeration, freezing or other storage functions, such as refrigerators, freezers, etc.

[0100] Those skilled in the art should also understand that the terms "upper", "lower", "front", "back", "top", "bottom", etc. used to indicate orientation or positional relationships in the embodiments of the present invention are based on the actual usage status of the microfluidic detection system 1 and the refrigerator 100. These terms are only used to facilitate the description and understanding of the technical solution of the present invention, and do not indicate or imply that the device or device referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they cannot be understood as limitations on the present invention.

[0101] At this point, those skilled in the art will recognize that, although a number of exemplary embodiments of the present invention have been shown and described in detail herein, many other variations or modifications consistent with the principles of the present invention may be directly determined or derived from the disclosure of the present invention without departing from the spirit and scope of the present invention. Therefore, the scope of the present invention should be understood and deemed to cover all such other variations or modifications.

Claims

1. A microfluidic detection system for refrigerators, characterized in that: include: A microfluidic biochip having an inlet, a communication port, and a detection cell formed therein, wherein the inlet, the detection cell, and the communication port are sequentially connected via a microfluidic channel to allow a sample liquid contacting the inlet to sequentially enter the detection cell via the inlet and the microfluidic channel; A chip mounting mechanism, for detachably mounting the microfluidic biochip thereon; A detection mechanism, used to detect the detection pool to obtain preset detection parameters of the sample liquid; a sample liquid driving device, connected to the communication port and used to force the sample liquid in contact with the sample inlet to enter the microfluidic channel and flow to the detection cell through the microfluidic channel; as well as a sealing docking mechanism for forming a fluid-tight connection between the microfluidic biochip and the sample liquid driving device; The sealing docking mechanism comprises: a sealing connector connected between the microfluidic biochip and the sample liquid driving device, wherein a connection channel is formed therein and passes through the sealing connector; the connection channel inside the sealing connector is in sealed communication with the sample liquid driving device; and an elastic pressure member, configured to apply an elastic force to the sealing connector to seal the sealing connector to the microfluidic biochip, thereby sealingly connecting the sample liquid driving device and the communication port of the microfluidic biochip through the connection channel; The elastic pressure member is disposed between the sealing connection member and the sample liquid driving device to apply an elastic force to the sealing connection member toward the microfluidic biochip, thereby utilizing the elastic force to cause the sealing connection member to elastically abut against the microfluidic biochip tightly. The chip mounting mechanism includes: Two elastic clamping jaws arranged opposite to each other to apply opposite forces to the microfluidic biochip located between the two elastic clamping jaws, thereby clamping the microfluidic biochip between the two elastic clamping jaws; an end plate, wherein the end plate and the microfluidic biochip are respectively located on opposite sides of the sealing connector; The elastic pressure member includes a spring, one end of the spring abuts against the end plate, and the other end abuts against the sealing connection member; A guide surface is provided on the inner side of the end of each of the two elastic clamps. The two guide surfaces extend obliquely toward each other along the installation direction of the microfluidic biochip to guide the microfluidic biochip to be installed between the two elastic clamps along its installation direction.

2. The microfluidic detection system according to claim 1, characterized in that: Also includes: The chip ejection mechanism is configured to operably apply forces in opposite directions to the two elastic clamps to cause the two elastic clamps to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip.

3. The microfluidic detection system according to claim 2, characterized in that: The chip ejection mechanism includes a cantilever button suspended on one side of the microfluidic biochip, and the cantilever button simultaneously abuts against the inner sides of the two elastic clamps arranged opposite to each other, so that when the cantilever button is subjected to a force toward the microfluidic biochip, an outward force is applied to the inner sides of the two elastic clamps, thereby causing the two elastic clamps to elastically deform in outward directions away from each other.

4. The microfluidic detection system according to claim 3, characterized in that: The cantilever button includes a button block and an abutment block protruding and extending from the inner side of the button block toward the microfluidic biochip in a direction gradually approaching the microfluidic biochip, and the two opposite side surfaces of the abutment block respectively abutting against the inner sides of the two elastic clamps are inclined toward each other in a direction gradually approaching the microfluidic biochip.

5. The microfluidic detection system according to claim 3, wherein The microfluidic biochip is vertically clamped between the two elastic clamping jaws; and The two elastic clamps are respectively located on the lateral sides of the microfluidic biochip, and the cantilever button is suspended on the front side of the microfluidic biochip so as to prompt the two elastic clamps to move away from each other in the lateral direction when it is subjected to a backward force, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip and allowing the microfluidic biochip to fall under the action of its own gravity.

6. The microfluidic detection system according to claim 1, wherein Also includes: A sample stage is provided below the microfluidic biochip for placing a sample cup, wherein the sample cup is used to hold a sample liquid; and The sample stage is configured to move in a controlled or operative manner so as to transport the sample cup placed thereon to a position where the sample liquid in the sample cup is allowed to contact the sample inlet of the microfluidic biochip.

7. The microfluidic detection system according to claim 6, wherein: The sample stage comprises: a support table for supporting the sample cup; and The oscillator is arranged on the supporting platform and is used to oscillate the sample cup after the sample cup is placed on the supporting platform, so that the buffer solution and the sample in the sample cup are fully mixed to produce the sample liquid.

8. A refrigerator, characterized in that: The microfluidic detection system comprises any one of claims 1-7.

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