Heating device of nucleic acid extractor and nucleic acid extractor

Abstract

The present invention provides a heating device for a nucleic acid extractor and a nucleic acid extractor, which can more effectively control the heating temperature. The heating device includes a heating strip assembly, a heat insulation cover, a heat insulation pressing strip, and a cooling fan; the heating strip assembly includes a heating strip body and a heating head, and the heating head is located at the upper end of the heating strip body; the heat insulation cover has an upper opening and a lower opening, the heat insulation cover is sleeved on the heating strip assembly and the heating head extends out from the upper opening; the heat insulation pressing strip seals the lower opening of the heat insulation cover to form a fully enclosed space among the heat insulation pressing strip, the heat insulation cover, and the heating head, and the heating strip body is enclosed in the fully enclosed space; heat dissipation holes are formed in the heat insulation cover and / or the heat insulation pressing strip, and the cooling fan is arranged facing at least one heat dissipation hole.

Description

Technical Field

[0001] The present invention relates to the technical field of nucleic acid extraction, and particularly relates to a heating device for a nucleic acid extractor and a nucleic acid extractor. Background Art

[0002] The nucleic acid extraction technology is an important method for realizing precision medicine in the fields of biology and medicine. In nucleic acid extraction experiments, some reagents need to be heated to appropriate reaction temperatures. The function of the heating device of the nucleic acid extractor is to heat the reagents to appropriate temperatures to ensure the accuracy of nucleic acid extraction experiments. When the volume of the reagent to be heated is large or the reaction temperature is high, an efficient heating device is a powerful guarantee for ensuring the rapid and smooth progress of the experiment.

[0003] Currently, in the heating devices of nucleic acid extractors used in the market, the heat insulation of the heating strip assembly adopts a semi-surrounding heat insulation method. The upper half of the heating strip assembly is wrapped with heat insulation materials for heat insulation, while the lower half of the heating strip assembly is not insulated and is exposed outside, and heat sinks are provided in the lower half for heat dissipation.

[0004] When the above heating device is heating, the lower half of the heating strip assembly will dissipate heat simultaneously. When the reagent volume in the reaction well is small and the temperature requirement is not high, heating can be better achieved. However, when the reagent volume in the reaction well is relatively large or the temperature requirement is high, the above heating device is difficult to control the heating temperature because high heating input is accompanied by high heat dissipation, and a good heating effect cannot be guaranteed. Summary of the Invention

[0005] The present invention provides a heating device for a nucleic acid extractor and a nucleic acid extractor, which can more effectively control the heating temperature.

[0006] The first aspect of the present invention provides a heating device for a nucleic acid extractor, including a heating strip assembly, a heat insulation cover, a heat insulation pressing strip, and a cooling fan;

[0007] The heating strip assembly includes a heating strip body and a heating head, and the heating head is located at the upper end of the heating strip body;

[0008] The heat insulation cover has an upper opening and a lower opening, and the heat insulation cover is sleeved on the heating strip assembly and the heating head extends out from the upper opening;

[0009] The heat insulation pressing strip seals the lower opening of the heat insulation cover to form a fully enclosed space among the heat insulation pressing strip, the heat insulation cover, and the heating head, and the heating strip body is enclosed in the fully enclosed space;

[0010] Heat dissipation holes are provided on the heat insulation cover and / or the heat insulation pressing strip, and the cooling fan is arranged facing at least one heat dissipation hole.

[0011] According to an embodiment of the present invention,

[0012] At least one side of the heat insulation cover is provided with at least one row of heat dissipation holes;

[0013] At least one row of heat dissipation holes is provided on the heat insulation pressing strip.

[0014] According to an embodiment of the present invention,

[0015] The heat dissipation fan is arranged at the bottom of the heat insulation pressing strip and faces the heat dissipation holes of the heat insulation pressing strip.

[0016] According to an embodiment of the present invention,

[0017] There is a gap between at least one side of the heating strip body and the corresponding side wall of the heat insulation cover.

[0018] According to an embodiment of the present invention,

[0019] There is a gap between the bottom of the heating strip body and the heat insulation pressing strip.

[0020] According to an embodiment of the present invention,

[0021] Heat dissipation ribs are further arranged at the bottom of the heating strip body.

[0022] According to an embodiment of the present invention,

[0023] The heat dissipation ribs and the heating strip body are of an integral structure.

[0024] According to an embodiment of the present invention,

[0025] The size of the upper end opening of the heat insulation cover matches the size of the heating head, so that the heating head can seal the upper end opening of the heat insulation cover.

[0026] According to an embodiment of the present invention,

[0027] The heat dissipation fan is used for: not supplying air when the heating device is heating, and starting to supply air when the heating device finishes heating.

[0028] According to an embodiment of the present invention,

[0029] The heating strip body and the heating head are of an integral structure, and both are made of metal materials.

[0030] According to an embodiment of the present invention,

[0031] The heating strip body and the heating head are of a separated structure, the heating strip body is made of metal materials, and the heating head is made of flexible heat-conducting materials;

[0032] The first surface of the heating head is in contact with the heating strip body, and the second surface of the heating head can be in contact with the bottom of the deep well plate to transfer the heat of the heating strip body to the deep well plate. The first surface and the second surface are two different surfaces of the heating head.

[0033] According to an embodiment of the present invention,

[0034] The heating strip body has a convex portion;

[0035] The first surface of the heating head has a groove matching the convex portion. The heating head is sleeved on the convex portion of the heating strip body through the groove so that the first surface is in contact with the convex portion of the heating strip body.

[0036] According to an embodiment of the present invention,

[0037] The bottom of the deep well plate has a plurality of bumps;

[0038] The heating head has a plurality of pits corresponding to the plurality of bumps, and the pits can be in contact with the bumps.

[0039] According to an embodiment of the present invention,

[0040] The heating head is made of heat-conducting silicone rubber.

[0041] The present invention also provides a nucleic acid extractor, including the heating device of the nucleic acid extractor as described in the foregoing embodiments.

[0042] The present invention has the following beneficial effects:

[0043] In the embodiment of the present invention, since a fully enclosed space is formed among the heat insulation strip, the heat insulation cover, and the first heating head, the first heating strip body is enclosed in the fully enclosed space. When heating, the cooling fan can be turned off, so that the air in the fully enclosed space is static. The thermal conductivity of static air is extremely low. Even if there are heat dissipation holes in the heat insulation cover and / or the heat insulation strip, it is not easy to dissipate heat through the heat dissipation holes. Compared with the semi-enclosed method of the first heating strip body, full-enclosed heat insulation can make the heating and heat preservation effects better, and can more quickly and effectively heat the reagent to be heated to the required temperature, improving the heating efficiency. Especially for large-volume or high-temperature reaction reagents, the effect is good; and when heat dissipation is required, the cooling fan can be controlled to work, and air is supplied into the fully enclosed space through the heat dissipation holes, so that gas convection is generated inside the fully enclosed space, and thus convection heat dissipation can be carried out through the heat dissipation holes, and the heat dissipation effect is also very good. Description of the Drawings

[0044] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0045] Figure 1 is an exploded structural schematic diagram of a heating device without a cooling fan in an embodiment of the present invention;

[0046] Figure 2 is an assembled structural schematic diagram of a heating device without a cooling fan in an embodiment of the present invention;

[0047] Figure 3 is an exploded structural schematic diagram of a heating device without a cooling fan in another embodiment of the present invention;

[0048] Figure 4 is a structural schematic diagram of a heating device without a cooling fan in an embodiment of the present invention when it is installed on the accommodating table of a nucleic acid extractor;

[0049] Figure 5 is a structural schematic diagram of a heating device with a cooling fan in an embodiment of the present invention when it is installed on the accommodating table of a nucleic acid extractor.

[0050] Explanation of reference numerals:

[0051] Heating device 10; heat insulation cover 100; upper end opening 101; first heat dissipation hole 102; heat insulation pressing strip 200; second heat dissipation hole 201; first heating strip body 301; first heating head 302; first pit 3021; first electronic component 303; first heat dissipation rib 304; second heating strip body 401; protruding portion 4011; second heating head 402; second pit 4021; second electronic component 403; second heat dissipation rib 404; accommodating table 20; deep hole plate 30; cooling fan 40. Detailed implementation manners

[0052] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0053] In the description, claims and the above drawings of the present invention, terms such as "first", "second", "third", "fourth", etc. (if any) are used to distinguish similar objects and do not necessarily describe a specific order or sequence. It should be understood that the data used in this way can be interchanged under appropriate circumstances so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0054] The technical solution of the present invention will be described in detail below with specific embodiments. These specific embodiments can be combined with each other, and the same or similar concepts or processes may not be repeated in some embodiments.

[0055] Figure 1 and Figure 2 FIG. shows a heating device 10 according to an embodiment of the present invention. The heating device 10 can be applied to a nucleic acid extractor and can be used to heat reagents in a deep well plate 30. The heating device 10 may include a first heating strip assembly, a heat insulation cover 100, a heat insulation pressing strip 200, and a cooling fan ( Figure 5 FIG. shows the cooling fan 40, Figure 1 and 2 not shown in).

[0056] The first heating strip assembly may include a first heating strip body 301 and a first heating head 302. The first heating head 302 is located at the upper end of the first heating strip body 301. In this embodiment, the upper end of the first heating strip body 301 refers to the end that is closer to the deep well plate ( Figure 1 and 2 not shown in) after being installed on the nucleic acid extractor.

[0057] The upper end surface of the first heating head 302 can be in contact with the bottom of the deep well plate to transfer the heat of the heating strip body to the deep well plate. The bottom of the deep well plate may have a bump. In this embodiment, the upper end surface of the first heating head 302 may have a first pit 3021, and the first pit 3021 can cooperate with the bump at the bottom of the deep well plate to achieve better contact between the first heating head 302 and the deep well plate.

[0058] Of course, the first heating strip assembly may further include other components, such as a first electronic component 303. A cavity is provided in the first heating strip body 301 (the cavity can be opened or closed by a cover, and the cover is not shown in the figure). The first electronic component 303 is built in the cavity and is connected to an external power supply and a control device through a circuit. The circuit can pass through the first heating strip body 301 and the heat insulation cover 100. Optionally, the first electronic component 303 may include a heating sheet, a temperature sensor, etc., and is not specifically limited.

[0059] The heat insulation cover 100 has an upper end opening 101 and a lower end opening (the lower end opening is not marked in the figure). The heat insulation cover 100 is sleeved on the first heating strip assembly, and the first heating head 302 extends out from the upper end opening 101. The lower end opening can be used to place the first heating strip assembly into the heat insulation cover 100.

[0060] The upper end opening 101 is located at the upper end of the heat insulation cover 100, and the lower end opening can be located at the lower end of the heat insulation cover 100. The lower end can be the end opposite to the upper end. The size of the lower end opening can be larger than that of the upper end opening 101, so that the first heating strip assembly can enter from the lower end opening and cannot go out from the upper end opening 101. Of course, the upper end opening 101 is large enough for the first heating head 302 to extend out.

[0061] The heat insulation pressing strip 200 seals the lower end opening of the heat insulation cover 100 to form an all-round enclosed space among the heat insulation pressing strip 200, the heat insulation cover 100, and the first heating head 302. The first heating strip body 301 is surrounded in the all-round enclosed space.

[0062] Optionally, the heat insulation pressing strip 200 can be fixed to the lower end opening of the heat insulation cover 100 by a snap-fastening method to seal the lower end opening. Of course, the fixing method of the heat insulation pressing strip 200 to the heat insulation cover 100 is not limited to this. For example, it can also be connected and fixed through an external connecting piece.

[0063] The all-round enclosed space means that there are blocking walls at the upper, lower, front, rear, left, and right ends of the first heating head 302. Among them, the upper blocking wall can be composed of the first heating head 302 and a part of the wall of the heat insulation cover 100, the front, rear, left, and right blocking walls can be composed of the four side walls of the heat insulation cover 100, and the lower blocking wall can be composed of the heat insulation pressing strip 200.

[0064] Heat dissipation holes are provided on the heat insulation cover 100 and / or the heat insulation pressing strip 200. The number and specific positions of the heat dissipation holes are not limited.

[0065] Preferably, a row of first heat dissipation holes 102 are respectively formed on both side surfaces of the heat insulation cover 100, and a row of second heat dissipation holes 201 are formed on the heat insulation pressing strip 200. Among them, the two side surfaces of the heat insulation cover 100 can be the two side surfaces with larger areas, and the row of second heat dissipation holes 201 on the heat insulation pressing strip 200 can be arranged in the length direction of the heat insulation pressing strip 200. It can be understood that the above method is only a preferred method, and it is not actually limited to this. For example, multiple rows of heat dissipation holes can also be respectively formed on both sides of the heat insulation cover 100, or only one row or multiple rows of heat dissipation holes can be formed on one side surface of the heat insulation cover 100, and multiple rows of heat dissipation holes can also be formed on the heat insulation pressing strip 200, and no specific limitation is made.

[0066] The number of heat dissipation holes in a row is multiple. The size of each heat dissipation hole is much smaller than the upper end opening 101 or the lower end opening. For example, the diameter of each heat dissipation hole can be at the millimeter level, such as the diameter can be less than 5 mm. Of course, no specific size limitation is made.

[0067] The heat dissipation fan 40 is arranged facing at least one heat dissipation hole. Preferably, the heat dissipation fan 40 is arranged at the bottom of the heat insulation pressing strip 200 and faces the second heat dissipation holes 201 of the heat insulation pressing strip 200. In this way, it is beneficial to the installation of the heat dissipation fan 40 and it is also convenient for multiple heating devices 10 to share the same heat dissipation fan 40. Of course, the position of the heat dissipation fan 40 is not limited to this. For example, it can also be arranged on one side of the heat insulation cover 100 and face the first heat dissipation holes 102 of the heat insulation cover 100.

[0068] The heat dissipation fan 40 can stop supplying air when the heating device 10 is heating, and start supplying air when the heating device 10 finishes heating.

[0069] In the above embodiment, since a fully enclosed space is formed among the heat insulation pressing strip 200, the heat insulation cover 100, and the first heating head 302, and the first heating strip body 301 is enclosed in the fully enclosed space, the heat dissipation fan 40 can stop working during heating, so that the air in the fully enclosed space is static. The thermal conductivity of the static air is extremely low. Even if there are heat dissipation holes on the heat insulation cover 100 and / or the heat insulation pressing strip 200, it is not easy to dissipate heat through the heat dissipation holes. Compared with the way that the first heating strip body 301 is semi-enclosed, full enclosure heat insulation can make the heating and heat preservation effects better, and can more quickly and effectively raise the temperature of the reagent to be heated to the required temperature, improving the heating efficiency. Especially for large-volume or high-temperature reaction reagents, the effect is good; and when heat dissipation is required, the heat dissipation fan 40 can be controlled to work, and air is supplied into the fully enclosed space through the heat dissipation holes, so that gas convection is generated inside the fully enclosed space, and thus convective heat dissipation can be carried out through the heat dissipation holes, and the heat dissipation effect is also very good.

[0070] In addition, generally, multiple heating devices 10 are provided on the nucleic acid extractor. In the embodiments of the present invention, the fully enclosed heat insulation method greatly limits the heat dissipation of the heating strip body during the heating process and greatly reduces the mutual influence between adjacent heating strip bodies.

[0071] Optionally, there is a gap between at least one side surface of the first heating strip body 301 and the corresponding side wall of the heat insulation cover 100. Here, the at least one side surface may refer to the side surface provided with heat dissipation holes. In this way, during heat dissipation, convection can be formed in the space of the gap, making the heat dissipation effect better.

[0072] Optionally, there is a gap between the bottom of the first heating strip body 301 and the heat insulation pressing strip 200. Similarly, it is beneficial to form convection in the fully enclosed space during heat dissipation for easy heat dissipation.

[0073] Preferably, referring to Figure 1 and Figure 2 , there are gaps between both side surfaces of the heat insulation cover 100 provided with the first heat dissipation holes 102 and the first heating strip body 301, and there is also a gap between the bottom of the first heating strip body 301 and the heat insulation pressing strip 200. Thus, when the cooling fan 40 supplies air to the second heat dissipation holes 201 of the heat insulation pressing strip 200, convection is formed in the gaps in the fully enclosed space, and the airflow carries the heat out from the first heat dissipation holes 102 of the heat insulation cover 100, and the heat dissipation effect is better.

[0074] Optionally, referring to Figure 1 , the bottom of the first heating strip body 301 is further provided with first heat dissipation ribs 304, and they can be arranged in the length direction of the first heating strip body 301. The first heat dissipation ribs 304 can be arranged in the gap between the first heating strip body 301 and the heat insulation pressing strip 200. Optionally, the first heat dissipation ribs 304 can be in contact with the heat insulation pressing strip 200, so that the heat insulation pressing strip 200 can press the entire first heating strip assembly tightly in the heat insulation cover 100.

[0075] Due to the presence of the first heat dissipation ribs 304, the heat dissipation area of the first heating strip body 301 is larger. Then, when the airflow passes through, more heat can be carried away, and the heat dissipation effect is better.

[0076] Preferably, the first heat dissipation ribs 304 and the first heating strip body 301 are of an integral structure. For example, the first heat dissipation ribs 304 and the first heating strip body 301 can be integrally formed and can be made of the same material by the same mold. Here, the material can specifically be a metal material, specifically any one of copper, aluminum, iron, etc. with good thermal conductivity or an alloy material containing any one of these elements.

[0077] Optionally, referring to Figure 1 and Figure 2, the size of the upper opening 101 of the heat shield 100 matches the size of the first heating head 302, so that the first heating head 302 can seal the upper opening 101 of the heat shield 100. In this way, heat dissipation from the upper opening 101 of the heat shield 100 can be avoided, ensuring the heat dissipation efficiency.

[0078] Optionally, referring to Figure 1 , the first heating strip body 301 and the first heating head 302 are of an integral structure and are both made of a metal material, specifically any one of copper, aluminum, iron, etc. with good thermal conductivity or an alloy material containing any one of these elements. In one example, the first heating strip body 301, the first heating head 302, and the first heat dissipation rib 304 can be integrally formed.

[0079] The above-mentioned metal material is a hard material. Since there must be a dimensional error between the deep hole plate and the first heating head 302, when the upper surface of the first heating head 302 contacts the bottom of the deep hole plate (especially the contact between the first pit 3021 and the convex block), the two cannot fit perfectly. Or rather, there are more or less some parts of the bottom of the deep hole plate that cannot fit perfectly with the first heating head 302, which results in some air gaps between the two. And the thermal conductivity of air is extremely low, and the thermal conductivity of air between 0 and 100 °C is between 0.024 and 0.031 W / m·K, which will have a great impact on the heating efficiency.

[0080] Another embodiment of the present invention can solve the above problem of low heating efficiency caused by poor contact between the heating head and the deep hole plate.

[0081] Figure 3 Fig. shows the heating device 10 of another embodiment of the present invention. The second heating strip assembly included in the heating device 10 in this embodiment is different from the first heating strip assembly in the previous embodiment ( Figure 1 shown).

[0082] Referring to Figure 3 , the second heating strip assembly includes a second heating strip body 401 and a second heating head 402. The second heating strip body 401 and the second heating head 402 are of a separated structure. The second heating strip body 401 is made of a metal material, and the second heating head 402 is made of a flexible heat-conducting material.

[0083] The first surface of the second heating head 402 is attached to the second heating strip body 401, and the second surface of the second heating head 402 can be attached to the bottom of the deep hole plate to transfer the heat of the second heating strip body 401 to the deep hole plate. The first surface and the second surface are two different surfaces of the second heating head 402.

[0084] The second surface is, for example, the upper end surface of the second heating head 402, specifically the surface of the second heating head 402 facing the deep well plate when the second heating device 10 is installed on the nucleic acid extractor. The first surface is, for example, the lower end surface of the second heating head 402, specifically the end surface opposite to the upper end surface of the second heating head 402.

[0085] In this embodiment, since the second heating strip body 401 and the second heating head 402 are of a separated structure, and the second heating head 402 is made of a flexible heat-conducting material, due to its flexible property, on the one hand, the second heating head 402 can be well attached to the second heating strip body 401, and on the other hand, it can be well attached to the deep well plate, avoiding poor contact with the deep well plate and thus generating gaps, and can play a better heat-conducting effect between the second heating strip body 401 and the deep well plate.

[0086] Optionally, the second heating strip body 401 has a convex portion 4011; the first surface of the second heating head 402 has a groove (not shown in the figure) matching the convex portion 4011, and the second heating head 402 is sleeved on the convex portion of the second heating strip body 401 through the groove, so that the first surface is attached to the convex portion 4011 of the second heating strip body 401.

[0087] The second heating head 402 and the second heating strip body 401 are fixed to each other in a sleeved manner, which can make the contact between the two more comprehensive and avoid the problem of poor contact caused by the action of external connecting parts.

[0088] Of course, the fixing manner of the second heating head 402 and the second heating strip body 401 is not specifically limited to this, and other fixing manners that can make there be no gap between the second heating head 402 and the second heating strip body 401 are also applicable.

[0089] Preferably, the surface of the convex portion 4011 is a smooth surface, and here the smooth surface means that there are no visible lines, particles, etc. to the naked eye. The smooth surface can make the contact between the second heating head 402 and the second heating strip body 401 more comprehensive and avoid forming gaps between the second heating head 402 and the second heating strip body 401.

[0090] Optionally, the bottom of the deep well plate 30 has a plurality of convex blocks; the second heating head 402 has a plurality of second pits 4021 corresponding to the plurality of convex blocks, and the second pits 4021 can be attached to the convex blocks.

[0091] Optionally, the shape of the second pit 4021 matches the convex block, and the pit is in a conical shape, or a hemispherical shape, or a columnar shape, or a combination of a columnar shape and a conical shape, or a combination of a columnar shape and a hemispherical shape, which can be specifically determined according to the shape of the convex block, as long as the second pit 4021 can be attached to the convex block.

[0092] Optionally, the second heating head 402 is made of thermally conductive silicone rubber, that is, the flexible thermally conductive material is thermally conductive silicone rubber. Thermally conductive silicone rubber is a non-fluid soft material, which is different from the fluid soft material, thermally conductive silicone grease.

[0093] In this embodiment, the second heating head 402 is made of thermally conductive silicone rubber and then fitted onto the second heating strip body 401. It has a certain elasticity and can be compressed when subjected to force, and can return to its original shape after the force is removed. This elasticity can make the second heating head 402 fit more closely with the second heating strip body 401 and the deep hole.

[0094] In addition to the above, the rest of the second heating strip assembly and the first heating strip assembly may be the same. For example, the second heating strip assembly may include a second electronic component 403, a cavity is provided in the second heating strip body 401 (the cavity can be opened or covered by a cover, and the cover is not shown in the figure), the second electronic component 403 is built in the cavity, and is connected to an external power supply and a control device through a line, wherein the line can pass through the second heating strip body 401 and the heat insulation cover 100. Optionally, the second electronic component 403 may include a heating plate, a temperature sensor, etc., which are not specifically limited. For another example, the second heating strip assembly may also include a second heat dissipation rib 404, which is provided at the bottom of the second heating strip body 401 and may be an integrated structure with the second heating strip body 401. For other similarities or differences, please refer to the contents of the aforementioned embodiments.

[0095] The present invention further provides a nucleic acid extractor, comprising the heating device 10 of the nucleic acid extractor according to the aforementioned embodiment.

[0096] See also Figure 4 and Figure 5 The nucleic acid extractor may include a accommodating table 20 for accommodating a deep well plate 30 (the remaining components of the nucleic acid extractor are not shown). The accommodating table 20 may have one or more accommodating parts, each of which may fix a deep well plate 30, and the bottom of each accommodating part may be provided with the heating device 10 of the aforementioned embodiment.

[0097] like Figure 4 and 5 As shown, three heating devices 10 can be arranged at the bottom of each accommodating portion, and the three heating devices 10 can share the same cooling fan 40, which is arranged at the bottom of the three heating devices 10. The number of heating strip assemblies in the three heating devices 10 may not be limited to one, Figure 5Among them, at the bottom of the leftmost first accommodating part, the heating strip assemblies included in the three heating devices 10 are 2, 3, and 1 respectively. The number of heating strip assemblies of each heating device 10 can be adjusted according to the reagent columns to be heated in the deep well plate 30. When the maximum number of consecutive columns to be heated is 3, the number of heating strip assemblies included in the corresponding heating device 10 is 3, and no specific limitation is made.

[0098] For other relevant content, reference can be made to the description of the heating device 10 in the foregoing embodiments, and details are not described herein again.

[0099] It can be understood that the first heating strip assembly and the second heating strip assembly in the embodiments of the present invention are two alternative embodiments of the heating strip assembly mentioned in the claims. The purpose of adding "first" and "second" is to distinguish the two alternative embodiments. The same applies to the internal components of these two heating strip assemblies, such as the heating strip body and the heating head.

[0100] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, and are not intended to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A heating device for a nucleic acid extractor, characterized in that, it includes a heating strip assembly, a heat insulation cover, a heat insulation pressing strip and a cooling fan; the heating strip assembly includes a heating strip body and a heating head, and the heating head is located at the upper end of the heating strip body; the heat insulation cover has an upper opening and a lower opening, and the heat insulation cover is sleeved on the heating strip assembly and the heating head extends out from the upper opening; the heat insulation pressing strip seals the lower opening of the heat insulation cover to form a fully enclosed space among the heat insulation pressing strip, the heat insulation cover and the heating head, and the heating strip body is enclosed in the fully enclosed space; heat dissipation holes are formed in the heat insulation cover and / or the heat insulation pressing strip, and the cooling fan is arranged towards at least one heat dissipation hole; at least one row of heat dissipation holes is formed in at least one side surface of the heat insulation cover; at least one row of heat dissipation holes is formed in the heat insulation pressing strip; a gap exists between at least one side surface of the heating strip body and the corresponding side wall of the heat insulation cover; a gap exists between the bottom of the heating strip body and the heat insulation pressing strip.

2. The heating device for a nucleic acid extractor according to claim 1, characterized in that, the cooling fan is arranged at the bottom of the heat insulation pressing strip and faces the heat dissipation holes of the heat insulation pressing strip.

3. The heating device for a nucleic acid extractor according to claim 1, characterized in that, heat dissipation ribs are further arranged at the bottom of the heating strip body.

4. The heating device for a nucleic acid extractor according to claim 3, characterized in that, the heat dissipation ribs and the heating strip body are of an integral structure.

5. The heating device for a nucleic acid extractor according to claim 1, characterized in that, the size of the upper opening of the heat insulation cover matches the size of the heating head, so that the heating head can seal the upper opening of the heat insulation cover.

6. The heating device for a nucleic acid extractor according to claim 1, characterized in that, the cooling fan is used for: not supplying air when the heating device is heating, and starting to supply air when the heating device finishes heating.

7. The heating device for a nucleic acid extractor according to claim 1, characterized in that, the heating strip body and the heating head are of an integral structure and are both made of metal materials.

8. The heating device for a nucleic acid extractor according to claim 1, characterized in that, the heating strip body and the heating head are of a separated structure, the heating strip body is made of metal materials, and the heating head is made of a flexible heat-conducting material; the first surface of the heating head is attached to the heating strip body, and the second surface of the heating head can be attached to the bottom of the deep well plate to transfer the heat of the heating strip body to the deep well plate, and the first surface and the second surface are two different surfaces of the heating head.

9. The heating device for a nucleic acid extractor according to claim 8, characterized in that, the heating strip body has a convex part; the first surface of the heating head has a groove matching the convex part, and the heating head is sleeved on the convex part of the heating strip body through the groove so that the first surface is attached to the convex part of the heating strip body.

10. The heating device for a nucleic acid extractor according to claim 8, characterized in that, The bottom of the deep well plate has a plurality of bumps; The heating head has a plurality of pits corresponding to the plurality of bumps, and the pits can fit with the bumps.

11. The heating device of the nucleic acid extractor according to claim 8, characterized in that the heating head is made of heat-conductive silicone rubber.

12. A nucleic acid extractor, characterized in that it includes the heating device of the nucleic acid extractor according to any one of claims 1-11.

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