Tip batch loading device, full-automatic chemiluminescence instant detection analyzer

Abstract

This invention provides a tip head batch loading device and a fully automated chemiluminescence real-time detection and analysis instrument. The tip head batch loading device, used in the fully automated chemiluminescence real-time detection and analysis instrument, includes: a consumable assembly comprising a tray and multiple tip heads on the tray; a consumable storage rack comprising opposing side plates and a platform located at the upper part of corresponding length ends of the two side plates, with a feeding guide rail formed on opposite sides of the two side plates, and the tray slidably connected to the feeding guide rail; and a feeding drive component capable of transferring the consumable assembly from a first position along the feeding track to a second position, and capable of transferring consumable assemblies with depleted tip heads from the second position to the platform, wherein the first and second positions correspond to the two ends of the length of the side plates, respectively. This invention reduces the space occupied by the device, and the feeding and pushing of the consumable assembly are both achieved through the feeding drive component, improving equipment safety and facilitating user operation.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of immunodiagnosis, and particularly relates to a Tip head batch loading device and a full-automatic chemiluminescence instant detection analyzer. BACKGROUND

[0002] Currently, consumable modules used in in-vitro diagnostic instruments often adopt two placement methods for disposable pipette tips (Tip heads) required by the instruments: one is fixed position placement, which requires users to put their hands into the instrument to place and take out, which is very inconvenient and has safety hazards; the second is horizontal double-track placement, which can drive the tray containing disposable pipette tips into or out of the instrument by a motor, but this solution has a high cost and occupies a large internal space, or only one track is used, so that the disposable pipette tips cannot be loaded online (i.e., the next tray cannot be loaded until the corresponding tray is taken out after the Tip heads carried by the tray are used up). SUMMARY

[0003] Therefore, the technical problem to be solved by the present application is to provide a Tip head batch loading device and a full-automatic chemiluminescence instant detection analyzer, which can reduce the space occupied by the device, and the feeding and pushing of the consumable assembly are both achieved by moving the feeding driving component, thereby improving the safety of the equipment and facilitating user operation.

[0004] To solve the above problems, the present application provides a Tip head batch loading device for use in a full-automatic chemiluminescence instant detection analyzer, comprising:

[0005] a consumable assembly, comprising a tray and a plurality of Tip heads on the tray;

[0006] a consumable rack, comprising oppositely arranged side plates, and a platform at the upper part of one end of the corresponding length of the two side plates, the opposite sides of the two side plates forming a feeding guide rail, and the tray being slidably connected to the feeding guide rail;

[0007] a feeding driving component, capable of transferring the consumable assembly from a first position to a second position along the feeding rail, and capable of transferring the consumable assembly with exhausted Tip heads from the second position to the platform, wherein the first position and the second position correspond to the two ends of the length of the side plates, respectively.

[0008] In some embodiments,

[0009] Each of the side plates is provided with a switching plate, the top end of the switching plate is pivotally connected with the platform, the bottom end of the switching plate is in contact with the top surface of the side plate under the action of its own weight, and the switching plate is inclined to the horizontal plane to facilitate the transfer of the consumable assembly from the first position to the second position and from the second position to the platform.

[0010] In some embodiments,

[0011] The included angle between the switching plate and the horizontal plane is a, and 10°≤a≤60°.

[0012] In some embodiments, the feeding driving component comprises:

[0013] A linear reciprocating driving component and a push-pull assembly, wherein the push-pull assembly is used to apply force to the consumable assembly, and the linear reciprocating driving component is used to drive the push-pull assembly to generate linear reciprocating motion along the extension direction of the feeding guide rail.

[0014] In some embodiments,

[0015] The push-pull assembly comprises a baffle deflection motor, a baffle is connected to the rotating shaft of the baffle deflection motor, and the baffle deflection motor can drive the baffle to switch between its initial position and a push-pull position.

[0016] In some embodiments,

[0017] The baffle is provided with an embedding groove, when the consumable assembly needs to be transferred from the first position to the second position, the vertical wall of the tray is partially inserted into the embedding groove; and / or, when the consumable assembly needs to be transferred from the second position to the platform, the side end surface of the baffle away from the baffle deflection motor partially abuts against the vertical wall of the tray.

[0018] In some embodiments,

[0019] The linear reciprocating driving component comprises a rotary motor, the push-pull assembly further comprises a fixed frame, the baffle deflection motor is arranged on the fixed frame, and the rotary motor is drivingly connected with the fixed frame through a belt transmission structure.

[0020] In some embodiments,

[0021] The rotary motor is arranged on the inner side of one of the two side plates, and the belt transmission structure is arranged on the outer side of the side plate, the belt transmission structure comprises a belt pulley sleeved on the rotating shaft of the rotary motor, a supporting roller arranged in a straight reciprocating path and spaced from the belt pulley, and a transmission belt arranged on the belt pulley and the supporting roller, and the transmission belt is fixedly connected with the fixed frame; or, the fixed frame is provided with a first sensor for detecting the initial position of the baffle.

[0022] In some embodiments,

[0023] The outer side of the side plate is further provided with a linear guide rail, and the fixed frame is slidably connected to the linear guide rail; and / or, the supporting roller has two.

[0024] The application also provides a full-automatic homogeneous chemiluminescence instant detection analyzer, comprising a Tip head batch loading device.

[0025] The application provides a Tip head batch loading device and a full-automatic chemiluminescence instant detection analyzer. The feeding guide rail and the platform form double tracks in a stacked manner. The consumable assembly with the Tip head is arranged on the lower feeding guide rail, and the consumable assembly with the exhausted Tip head is arranged on the upper platform. The device occupies less space. The feeding and pushing of the consumable assembly are realized by the feeding driving component. The user only needs to place the consumable assembly on the first position or take it away from the platform, without putting the hand into the interior of the device. The safety of the device is improved, and the user can operate the device conveniently. Meanwhile, the consumable assembly has multiple Tip heads, and the batch online loading function of the consumable is realized. BRIEF DESCRIPTION OF DRAWINGS

[0026] Figure 1 Fig. 1 is a perspective view of the Tip head batch loading device according to the application;

[0027] Figure 2 Fig. 2 is a perspective view of the Tip head batch loading device according to the application; Figure 1 Fig. 3 is a schematic view of the state in which the baffle and the tray are connected through the slot in the Tip head batch loading device according to the application;

[0028] Figure 3 Fig. 4 is a schematic view of the state in which the outer end surface of the baffle and the tray are in contact in the Tip head batch loading device according to the application. Figure 1

[0029] The reference signs are as follows:

[0030] ​211, tray; 212, Tip head; 221, side plate; 222, platform; 23, switching plate; 241, baffle deflection motor; 242, baffle; 2421, slot; 243, rotary motor; 244, fixing frame; 245, pulley; 246, support roller; 247, conveying belt; 248, linear guide rail; 249, first sensor. DETAILED DESCRIPTION

[0031] SUMMARY Figures 1 to 3 As shown, according to the embodiment of the present application, a Tip head batch loading device is provided for a full-automatic chemiluminescence instant detection analyzer, comprising: a consumable assembly including a tray 211 and a plurality of Tip heads 212 on the tray 211; a consumable rack including oppositely arranged side plates 221 and a platform 222 at the upper part of one end of the corresponding length of the two side plates 221, the opposite side of the two side plates 221 forming a feeding guide rail, and the tray 211 being slidingly connected to the feeding guide rail; a feeding driving component capable of transferring the consumable assembly from a first position to a second position along the feeding rail, and capable of transferring the consumable assembly with exhausted Tip heads 212 from the second position to the platform 222, wherein the first position and the second position correspond to the two ends of the length of the side plate respectively. In this technical solution, the feeding guide rail and the platform 222 form a double track stacked vertically, the consumable assembly with Tip heads 212 is on the lower feeding guide rail, and the consumable assembly with exhausted Tip heads 212 (i.e. only the tray 211) is placed on the upper platform 222, which can reduce the space occupied by the device, the feeding and pushing of the consumable assembly are both achieved by moving the feeding driving component, only the user needs to place the consumable assembly at the first position or take it away from the platform 222, without the need to put his hand into the interior, which improves the safety of the equipment and facilitates user operation. It should be particularly noted that in this technical solution, the consumable assembly has a plurality of Tip heads 212, and two consumable assemblies can be used in relay, which can realize the batch online loading function of consumables, avoid loading after the Tip heads 212 are exhausted, and speed up the testing speed.

[0032] The consumable assembly can be lifted between the first position and the platform 222, but such lifting needs to set up a corresponding lifting mechanism, which complicates the structure of the device, increases the cost and makes the control complicated. In some more preferred embodiments, a switching plate 23 is arranged between each side plate 221 and the platform 222, the top end of the switching plate 23 is pivotally connected to the platform 222, the bottom end of the switching plate 23 is connected to the top surface of the side plate 221 under the action of its own weight, and the switching plate 23 is arranged obliquely to the horizontal plane to facilitate the transfer of the consumable assembly from the first position to the second position and from the second position to the platform 222. It should be noted that the platform 222 at this time can be two guide rail sections arranged on the opposite sides of the two side plates 221, the top end of the switching plate 23 is in abutment with the guide rail section, and the bottom end of the switching plate 23 is in abutment with the feeding guide rail, so that when the tray 211 moves from the first position to the second position, the switching plate 23 is lifted upward (the bottom end of the switching plate 23 rotates upward around the pivot point at the top end), and the feeding is smooth. When the tray 211 moves from the second position to the first position, it is guided into the guide rail section under the guidance of the inclined switching plate 23, that is, it is placed on the platform 222. This structure design can realize the switching of the position of the tray 211 in the height direction only by the linear reciprocating motion of the feeding driving component, greatly simplifying the structure and control logic of the device, reducing the use of components, and reducing the design and manufacturing cost of the device. In some embodiments, the angle between the switching plate 23 and the horizontal plane is a, and 10°≤a≤60°, which can ensure smooth switching of the position of the tray 211 in the height direction while reducing the length of the side plate 221, making the overall device structure more compact.

[0033] In some embodiments, the feeding driving component includes a linear reciprocating driving component and a push-pull assembly, wherein the push-pull assembly is used to apply force to the consumable assembly, and the linear reciprocating driving component is used to drive the push-pull assembly to produce linear reciprocating motion along the extension direction of the feeding guide rail. In a specific embodiment, the push-pull assembly includes a baffle deflection motor 241, and a baffle 242 is connected to the rotating shaft of the baffle deflection motor 241. The baffle deflection motor 241 can drive the baffle 242 to switch between its initial position and a push-pull position. Specifically, the baffle 242 is in a vertical state, which is the push-pull position, and when the baffle 242 is in a horizontal state, it is the initial position. Figure 1 In this technical solution, the state change of the baffle 242 driven by the baffle deflection motor 241 realizes the connection with the tray 211, making the structure of the push-pull assembly compact and compact.

[0034] The baffle 242 is provided with an embedding groove 2421, when the consumable assembly needs to be transferred from the first position to the second position, the vertical wall of the tray 211 is partially inserted into the embedding groove 2421, at this time, the baffle 242 will exert a pulling force on the tray 211 to ensure reliable stability of the connection; when the consumable assembly needs to be transferred from the second position to the platform 222, the side end surface of the baffle 242 away from the baffle deflection motor 241 partially abuts against the vertical wall of the tray 211, at this time, the baffle 242 exerts a pushing force on the tray 211, in this working condition, the tray 211 does not need to be inserted into the embedding groove 2421, so that accurate positioning between the baffle 242 and the tray 211 is not needed, and the control logic is simplified.

[0035] In some embodiments, the consumable rack is also provided with a positioning card structure, which can accurately position the tray 211 in the first position, so that the relative position relationship between the baffle 242 and the tray 211 can be ensured through the specific displacement size of the baffle 242. For example, after the push-pull assembly is displaced by a first preset distance along the feeding guide rail, the push-pull assembly can contact the vertical wall of the tray 211, at this time, the push-pull assembly is controlled to stop moving forward, and the baffle 242 is controlled to be in the initial position, then the push-pull assembly is controlled to move forward by a second preset distance to align the embedding groove 2421 with the vertical wall of the tray 211, and then stop moving forward and control the baffle 242 to be in the push-pull position, then control the push-pull assembly to move in the opposite direction by a third preset distance to reach the second position, and complete feeding once. When all the Tip heads 212 on the tray 211 are used up, the push-pull assembly is controlled to move forward by a fourth preset distance towards the first position, and under the guidance of the switching plate 23, the tray 211 is automatically placed on the platform above, and the forward feeding, forward output and stacking of the consumables are realized.

[0036] The straight reciprocating driving component comprises a rotary motor 243, and the push-pull assembly further comprises a fixing frame 244, the baffle deflection motor 241 is arranged on the fixing frame 244, and the rotary motor 243 can drive the displacement of the fixing frame 244 by adopting a gear transmission structure or a screw rod transmission structure, in a preferred embodiment, the rotary motor 243 is drivingly connected with the fixing frame 244 by a belt transmission structure, the belt transmission structure can have a larger length adjustment capacity, has a lower manufacturing cost, and is more flexible in the arrangement of specific components. Specifically, the rotary motor 243 is arranged on the inner side of one of the two side plates 221, the belt transmission structure is arranged on the outer side of the side plate 221, the belt transmission structure comprises a pulley 245 sleeved on the rotating shaft of the rotary motor 243, a supporting roller 246 arranged in a straight reciprocating path and spaced from the pulley 245, and a transmission belt 247 arranged on the pulley 245 and the supporting roller 246, and the transmission belt 247 is fixedly connected with the fixing frame 244. The supporting roller 246 has two, the two supporting rollers 246 are arranged adjacent to each other in an up-down direction, and the sum of the diameters of the two supporting rollers 246 is equal to the diameter of the pulley 245, so that the transmission belt 247 is in a horizontal transmission state, and in this technical solution, two supporting rollers 246 are adopted instead of a roller with the same diameter as the pulley 245, which can save installation space, and at the same time, can avoid matching a larger diameter rotating shaft with a larger bearing, and can reduce the load of the driving motor.

[0037] A first sensor 249 (which can be a proximity switch) is arranged on the fixing frame 244, and is used to detect the initial position of the baffle 242, and a second sensor (not shown in the figure, which can be a diffuse reflection sensor) is also arranged on the fixing frame 244, and is used to detect whether the tray 211 is successfully connected with the baffle 242, and it can be understood that if the connection is successful, the tray 211 will be detected, and if the connection is not successful, the tray 211 will not be detected.

[0038] In some embodiments, the outer side of the side plate 221 is further provided with a straight guide rail 248, and the fixing frame 244 is slidably connected to the straight guide rail 248, so as to ensure the stability of the straight reciprocating movement.

[0039] According to the embodiments of the present application, a full-automatic homogeneous chemiluminescence point-of-care testing (POCT) analyzer is also provided, which comprises the Tip head batch loading device.

[0040] Those skilled in the art can easily understand that the above advantageous modes can be freely combined and superimposed without conflict.

[0041] The above merely preferred embodiments of the present application and are not intended to limit the present application. Any modification, equivalent replacement and improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application. The above is merely the preferred embodiments of the present application, and it should be pointed out that, for ordinary skilled in the art, without departing from the technical principles of the present application, a number of improvements and variations can be made, and these improvements and variations should be considered as the protection scope of the present application.

Claims

1. A Tip head batch loading device for a fully automatic chemiluminescence instant detection analyzer, characterized in that, include: Consumable assembly, including a tray (211) and a plurality of tip heads (212) on the tray (211). The consumables rack includes opposing side plates (221) and a platform (222) located at the upper part of one end of the corresponding length of the two side plates (221). A feeding guide is formed on the opposite side of the two side plates (221), and the tray (211) is slidably connected to the feeding guide. The feeding drive component is capable of transferring the consumable assembly from a first position to a second position along the feeding guide, and is capable of transferring the consumable assembly with depleted Tip head (212) from the second position to the platform (222), wherein the first position and the second position correspond to the two ends of the length of the side plate respectively; a switching plate (23) is provided between each side plate (221) and the platform (222), the top end of the switching plate (23) is pivotally connected to the platform (222), the bottom end of the switching plate (23) is in contact with the top surface of the side plate (221) under its own weight, and the switching plate (23) is inclined to the horizontal plane to facilitate the transfer of the consumable assembly from the first position to the second position and from the second position to the platform (222); The platform (222) consists of two guide rail sections constructed on the opposite sides of the two side plates (221). The top of the switching plate (23) is connected to the guide rail section, and the bottom of the switching plate (23) is connected to the feeding guide rail. Thus, when the tray (211) moves from the first position to the second position, the switching plate (23) can be lifted upward to feed the material smoothly. When the tray (211) moves from the second position to the first position, it is guided by the inclined switching plate (23) to enter the guide rail section, that is, it is placed on the platform (222).

2. The tip header batch loading device according to claim 1, characterized in that, The angle of inclination between the switching plate (23) and the horizontal plane is a, 10°≤a≤60°.

3. The Tip head batch loader of claim 1, wherein, The feeding drive component includes: A linear reciprocating drive component and a push-pull assembly, wherein the push-pull assembly is used to apply force to the consumable assembly, and the linear reciprocating drive component is used to drive the push-pull assembly to generate linear reciprocating motion along the extension direction of the feed guide rail.

4. The tip header batch loading device according to claim 3, characterized in that, The push-pull assembly includes a baffle deflection motor (241), on which a baffle (242) is connected. The baffle deflection motor (241) can drive the baffle (242) to switch between its initial position and the push-pull position.

5. The tip header batch loading device according to claim 4, characterized in that, The baffle (242) is provided with an embedding groove (2421), when the consumable assembly needs to be transferred from the first position to the second position, the vertical wall of the tray (211) is partially inserted into the embedding groove (2421); and / or, when the consumable assembly needs to be transferred from the second position to the platform (222), the side end surface of the baffle (242) away from the baffle deflection motor (241) partially abuts against the vertical wall of the tray (211).

6. The Tip head batch loading device according to claim 4, wherein, The linear reciprocating driving component comprises a rotary motor (243), the push-pull assembly further comprises a fixed frame (244), the baffle deflection motor (241) is arranged on the fixed frame (244), and the rotary motor (243) is drivingly connected with the fixed frame (244) through a belt transmission structure.

7. The Tip head batch loading device according to claim 6, wherein, The rotary motor (243) is arranged on the inner side of one of the two side plates (221), the belt transmission structure is arranged on the outer side of the side plate (221), the belt transmission structure comprises a pulley (245) sleeved on the rotating shaft of the rotary motor (243), a supporting roller (246) arranged at intervals with the pulley (245) on a linear reciprocating path, and a transmission belt (247) arranged on the pulley (245) and the supporting roller (246), the transmission belt (247) is fixedly connected with the fixed frame (244); or, the fixed frame (244) is provided with a first sensor (249) for detecting the initial position of the baffle (242).

8. The Tip head batch loading device according to claim 7, wherein, The outer side of the side plate (221) is further provided with a linear guide rail (248), and the fixed frame (244) is slidably connected to the linear guide rail (248); and / or, the supporting roller (246) has two.

9. A fully automatic homogeneous chemiluminescence immunoassay analyzer comprising a Tip head batch loading device, characterized in that, The Tip head batch loading device is the Tip head batch loading device according to any one of claims 1 to 8.

Images