Conveying system

Abstract

The application discloses a delivery system suitable for delivering a ring shrink device to a target position, the ring shrink device comprising an anchor body (110) and a limiting part (131, 132), wherein a limiting ring (121, 122) is arranged on one side of the anchor body (110), the delivery system comprising: a delivery sheath, an inner cavity of the delivery sheath being a channel for delivering the ring shrink device to the target position; a push rod, the push rod having a plurality of independent through cavities (310), the push rod pushing the ring shrink device in the delivery sheath; a traction assembly, the traction assembly being connected with the ring shrink device after passing through the cavities (310); and an operation control assembly, the operation control assembly pushing the anchor body (110) to the target position and clamping or disengaging the limiting ring (121, 122) from the limiting part (131, 132) by controlling the delivery sheath, the push rod and the traction assembly.

Description

TECHNICAL FIELD

[0001] The present invention relates to the field of interventional medical devices, and more particularly, to a delivery system. BACKGROUND

[0002] This section provides background information only and can not necessarily be prior art.

[0003] The mitral valve is a part of the heart that lies between the left atrium and the left ventricle. Blood is pumped from the left atrium into the left ventricle, and the mitral valve closes to prevent blood from being pumped back into the left atrium as the left ventricle contracts to pump blood into the body. In some patients, the mitral valve does not close properly, either due to a congenital deformity, disease, or injury, resulting in a condition known as regurgitation, in which blood is pumped into the atrium with each contraction of the heart muscle. Regurgitation is a serious, often rapidly worsening condition that reduces the efficiency of circulation and must be corrected.

[0004] Mitral valve disease is the leading heart valve disease. Heart valves are classified into four types according to their shape and location: the mitral valve, the tricuspid valve, the aortic valve, and the pulmonary valve. A normally functioning valve acts as a "one-way valve" to ensure that blood flow in the heart can only proceed in a fixed single direction without backflow. If the valve becomes stenotic or incompetent due to abnormal structure, functional degradation, or other diseases, it will affect the normal flow of blood in the heart, and thus progressively lead to abnormal heart function and eventually cause heart failure. Among all heart valve diseases, mitral valve disease is the type with the highest prevalence; according to Frost & Sullivan data, the proportion of mitral valve disease patients in the world and China accounted for 53.0% and 45.2% of all valve diseases in 2019, respectively, much higher than the proportion of aortic valve patients (25.1% globally and 22.6% in China).

[0005] Two common methods to repair a damaged mitral valve function are to replace the mitral valve with a mechanical valve through surgery, or to sew a flexible ring around the mitral valve to support the mitral valve. These surgeries are highly invasive because they require access to the heart through an opening in the patient's chest. Mitral valve regurgitation patients are often relatively fragile, thus increasing the risk of surgery.

[0006] Now through minimally invasive surgery treatment, is most heart valve disease is a better choice, the main intervention treatment way artificial chordae tendineae implantation, mitral annuloplasty and mitral valve edge to edge repair, etc. Among them, the annuloplasty has direct annuloplasty and indirect annuloplasty two kinds. Indirect annuloplasty is mainly to use the blood vessel tissue around the mitral annulus to shrink the mitral annulus, so that the mitral valve leaflet is closed tightly. Coronary sinus-cardiac vein is mainly the blood vessel around the mitral annulus, which also makes it the best implantation object of indirect annuloplasty. SUMMARY

[0007] Based on this, the application provides a delivery system, which has good pushability and flexibility, can deliver the ring shrinking device to the target position of the coronary sinus-cardiac vein, can reposition the ring shrinking device during the operation, and can unlock and recover the ring shrinking device.

[0008] To achieve this purpose, the application adopts the following technical solutions:

[0009] The application provides a delivery system, which is suitable for delivering a ring shrinking device to a target position, the ring shrinking device comprising an anchor body and a limiting part arranged at both ends of the anchor body, wherein a limiting ring is further arranged at both ends of the anchor body, the delivery system comprising: a delivery sheath, an inner cavity of the delivery sheath being a channel for delivering the ring shrinking device to the target position; a push rod, the push rod having a plurality of independent through cavities, the push rod pushing the ring shrinking device in the delivery sheath; a traction assembly, the traction assembly being connected with the ring shrinking device after passing through the cavities; and an operation control assembly, the operation control assembly pushing the anchor body to the target position and making the limiting ring be clamped into or separated from the limiting part by controlling the delivery sheath, the push rod and the traction assembly.

[0010] The delivery system provided by the application delivers the ring shrink device to the target position, the ring shrink device has an anchor body and limiting portions 131 and 132 arranged at both ends of the anchor body, and limiting rings 121 and 122 are arranged at both ends of the anchor body respectively, wherein, when the ring shrink device is delivered to the target blood vessel position, the ring shrink device is in an expanded state and the limiting rings 121 and 122 are clamped into the limiting portions 131 and 132, so that the ring shrink device is stably arranged in the blood vessel; when it is needed to reposition the ring shrink device, the delivery system disengages the limiting rings 121 and 122 from the limiting portions 131 and 132, the delivery system moves both the distal end and the proximal end of the anchor body to the target position, and the limiting rings of the anchor body are re-clamped into the limiting portions at the distal end and the proximal end, so that the repositioning of the ring shrink device in the blood vessel is completed; when it is needed to recover the ring shrink device, the delivery system disengages the limiting rings from the limiting portions, the ring shrink device is in a non-stable state in the blood vessel, and the delivery system recovers the ring shrink device.

[0011] In some embodiments of the delivery system of the application, the traction assembly comprises a first traction member and a second traction member, the first traction member and the second traction member are used to pull the limiting portions, wherein the first traction member and the second traction member extend to the distal end of the push rod through a cavity of the push rod, and the first traction member, the second traction member and the limiting portions are detachably connected.

[0012] In some embodiments of the delivery system of the application, the delivery system further comprises a connecting tube, the outer diameter of the connecting tube matches the cavity, the first traction member and the second traction member pass through the inner cavity of the connecting tube, and under the joint action of the first traction member and the second traction member, the proximal end limiting portion of the ring shrink device abuts against the distal end tube opening of the connecting tube.

[0013] In some embodiments of the delivery system of the application, the limiting portions and the distal end of the first traction member partially overlap each other, and a through hole is formed in the overlapping area, and the second traction member is pressed against the anchor body after passing through the through hole.

[0014] In some embodiments of the delivery system of the application, the traction assembly comprises a first traction member and a second traction member, wherein the first traction member and the second traction member extend to the distal end of the push rod through a cavity 310 of the push rod, and the first traction member, the second traction member and the limiting portions are detachably connected.

[0015] In some embodiments of the delivery system of the application, the limiting portions have an outer shape abutting against the distal end opening of the connecting tube, and at least the radial dimension of the limiting portions decreases from the distal end to the proximal end.

[0016] In some embodiments of the delivery system of the present application, the traction assembly comprises a third traction member and a fourth traction member, and a first guide member, wherein the first guide member is arranged along the axis of the cavity and detachably connected to the distal end of the loop constriction device; the third traction member is connected to the limiting ring along the first guide member, and under the action of the third traction member, the limiting ring can be separated from the limiting portion; the fourth traction member is connected to the limiting ring along the first guide member, and under the action of the fourth traction member, the limiting ring can be separated from the limiting portion.

[0017] In some embodiments of the delivery system of the present application, the operation control assembly comprises a first guide member fixing portion and a tail end fixing end, and the first guide member fixing portion and the tail end fixing end are threadedly connected.

[0018] In some embodiments of the delivery system of the present application, the operation control assembly comprises a first pull rod and a second pull rod, and a second guide member, the second guide member has a first position arranged at the proximal end and a second position arranged at the distal end; wherein the first pull rod is connected to the third traction member, the second pull rod is connected to the fourth traction member, and the first pull rod and the second pull rod are slidably switched between the first position and the second position along the second guide member.

[0019] In some embodiments of the delivery system of the present application, the operation control assembly further comprises a push rod fixing member and a push rod controller, wherein the push rod fixing member is fixedly connected to the push rod, and the push rod controller is connected to the push rod fixing member and controls the axial movement of the push rod in the delivery sheath through the push rod fixing member.

[0020] In some embodiments of the delivery system of the present application, the proximal end of the push rod fixing member is provided with a T-shaped boss structure, and the T-shaped boss structure only moves axially in the groove matched therewith.

[0021] In some embodiments of the delivery system of the present application, the operation control assembly further comprises a connecting tube fixing member, the connecting tube fixing member is connected to the proximal end of the connecting tube, wherein a first traction member fixing portion is arranged on the connecting tube fixing member, and the first traction member fixing portion is used for fixedly connecting the first traction member.

[0022] In some embodiments of the delivery system of the present application, the operation control assembly comprises a tail end screw and a second traction member fixing portion, the second traction member fixing portion is threadedly connected to the tail end screw, and the second traction member fixing portion is used for fixedly connecting the second traction member.

[0023] In some embodiments of the delivery system of the present application, the connecting tube fixing member is integrally formed with the tail end screw, or the connecting tube fixing member is detachably connected with the tail end screw.

[0024] In some embodiments of the delivery system of the present application, the second traction member fixing portion is provided with a plurality of groove structures, and a stopper is arranged in each groove structure to prevent relative movement between the second traction member fixing portion and the tail end screw.

[0025] In some embodiments of the delivery system of the present application, each of the first guide member fixing portions is provided with a plurality of groove structures, and a stopper is arranged in each groove structure to prevent relative movement between the first guide member fixing portion and the tail end screw.

[0026] In some embodiments of the delivery system of the present application, the delivery system further comprises a loader for preloading the ring shrink device, a distal end of the loader being connected with a proximal end of the delivery sheath; the operation control assembly further comprises a loader control portion connected with the loader and controlling axial movement of the delivery sheath through the loader. BRIEF DESCRIPTION OF DRAWINGS

[0027] Figure 1 A state diagram of the delivery system of the present application delivering a ring shrink device into the coronary sinus- great cardiac vein is schematically shown;

[0028] Figure 2 A structural diagram of the ring shrink device in the delivery system of the present application is schematically shown;

[0029] Figure 3 An expanded state of the ring shrink device in the delivery system of the present application in the coronary sinus- great cardiac vein is schematically shown;

[0030] Figure 4 A connecting relationship of the delivery system of the present application at a distal end of the ring shrink device is schematically shown;

[0031] Figure 5 A connecting relationship of the delivery sheath and the loader in the delivery system of the present application is schematically shown;

[0032] Figure 6 A cross-sectional view of the loader preloading the ring shrink device in the delivery system of the present application is schematically shown;

[0033] Figure 7 A push rod and a push rod fixing member in the delivery system of the present application are schematically shown;

[0034] Figure 8A cross-sectional view of the push rod 300 and the push rod fixing member 511 in the delivery system of the present application is shown schematically, wherein the inner diameter of the push rod fixing member 511 matches the outer diameter of the push rod 200,

[0035] Figure 9 A partial enlarged view of Figure 7

[0036] Figure 10 A connection relationship of the delivery system of the present application at the proximal end of the ring shrink device is shown schematically;

[0037] Figure 11 A connection relationship of the delivery system of the present application at the proximal end of the ring shrink device is shown schematically, wherein the proximal end limiting part 132 is arrow-shaped;

[0038] Figure 12 A connection relationship of the delivery system of the present application at the proximal end of the ring shrink device is shown schematically from another perspective;

[0039] Figure 13 A connection relationship of the connection tube of the delivery system of the present application and the ring shrink device is shown schematically;

[0040] Figure 14 A connection tube and a connection tube fixing member in the delivery system of the present application are shown schematically;

[0041] Figure 15 A partial enlarged view of Figure 14

[0042] Figure 16 An internal structure of the shell formed by the upper cover of the delivery handle and the lower cover of the delivery handle of the delivery system of the present application is shown schematically;

[0043] Figure 17 The delivery sheath pipe in the delivery system of the present application is shown schematically, wherein the distal end anchor limiting ring is clamped into the distal end limiting part, and the superior vena cava is expanded after the distal end anchor is locked;

[0044] Figure 18 A first pull rod and a second pull rod of the delivery system of the present application, and a second guide member are shown schematically;

[0045] Figure 19 A connection relationship of the first pull rod, the second pull rod and the second guide member of the delivery system of the present application is shown schematically;

[0046] Figure 20 A connection relationship of the first pull rod, the second pull rod and the second guide member of the delivery system of the present application is shown schematically;

[0047] Figure 21 ​​An operating state of the proximal anchor rod and the distal anchor rod in the delivery system of the present application is schematically shown;

[0048] Figure 22 A sectional view of the operation control assembly in the delivery system of the present application is schematically shown;

[0049] Figure 23 A split connecting tube fixing member 521 and a tail screw 524 in the delivery system of the present application are schematically shown;

[0050] Figure 24 And Figure 25 An exploded view of the operation control assembly in the delivery system of the present application is schematically shown.

[0051] Figure 26 A connection structure diagram of the delivery system of the present application is schematically shown.

[0052] The reference signs are as follows:

[0053] 100 ring shrinkage device; 110 anchor body; 111 proximal anchor; 112 distal anchor; 121 proximal anchor limiting ring (limiting ring); 122 distal anchor limiting ring (limiting ring); 131 distal limiting portion (limiting portion); 132 proximal limiting portion (limiting portion); 150 sleeve; 160 connecting rod;

[0054] 200 delivery sheath; 300 push rod; 310 cavity of the push rod; 311 cavity (for passing the connecting tube 700); 312 cavity (for passing the core wire 450); 313 cavity (for passing the proximal end 430 / distal end pull rope hole 440); 314 cavity (for passing the proximal end 430 / distal end pull rope hole 440);

[0055] 400 traction assembly; 410 first traction member (connecting wire); 420 second traction member (liner wire); 430 third traction member (proximal end pull rope); 440 fourth traction member (distal end pull rope); 450 first guide member (core wire); 451 third guide member (core wire guide member);

[0056] 500 operation control assembly; 600 loader; 700 connecting tube;

[0057] 511 push rod fixing member; 512 limiting structure (T-shaped boss structure); 513 push rod controller; 521 connecting tube fixing member; 522 first traction member fixing portion (connecting wire fixing portion); 523 second traction member fixing portion (liner wire fixing portion); 524 tail screw; 525 tail knob;

[0058] 531 First guide fixed part (core wire fixed part); 532 Tail fixed end; 533 Groove structure; 534 Stopper;

[0059] 541 First pull rod (proximal anchor pull rod); 542 Second pull rod (distal anchor pull rod); 543 Second guide (pull rod guide); 544 Second guide (pull rod guide); 545 Guide pressing block;

[0060] 551 First position; 552 Second position; 553 Fixed boss; 554 Fixed groove;

[0061] 560 Loader control part; 571 Conveying handle upper cover; 572 Conveying handle lower cover;

[0062] 800 Heart; 810 Great cardiac vein; 820 Coronary sinus; 830 Coronary circumflex artery; 840 Mitral valve; 850 Mitral valve annulus; 860 Tricuspid valve; 870 Aortic valve. DETAILED DESCRIPTION

[0063] In order to make the objects, technical solutions, and advantages of the present application clearer, the exemplary embodiments of the present disclosure will be described in more detail below with reference to the drawings. Although the exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure can be implemented in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that the present disclosure can be more thoroughly understood and the scope of the present disclosure can be conveyed completely to those skilled in the art.

[0064] It should be understood that the terms used herein are for the purpose of describing particular example embodiments only and are not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. The terms "comprises", "comprising", "includes", "including" and "has" are inclusive and therefore specify the presence of stated features, steps, operations, elements, and / or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and / or groups thereof. The method steps, processes, and operations described herein are not to be construed as necessarily requiring their performance in the particular order in which they are described, unless specifically indicated as such. It is also to be understood that additional or alternative steps can be employed.

[0065] Although the terms first, second, third, etc. can be used herein to describe various elements, components, regions, layers and / or sections, these elements, components, regions, layers and / or sections should not be limited by these terms. These terms can be only used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.

[0066] Spatially relative terms, such as "inner," "outer," "inward," "outward," "lower," "bottom," "top," "upper," and the like, can be used herein for ease of description to describe one element or feature's relationship to another element(s) or feature(s) as illustrated in the figures. Spatially relative terms can be intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "over" the other elements or features. Thus, the example term "below" can encompass both an orientation of above and below. The device can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

[0067] In addition, it needs to be noted that in the field of interventional medical devices, the end of a medical device or a delivery system for delivering the medical device that is closer to an operator is generally referred to as "proximal end" and the end that is further away from the operator is generally referred to as "distal end", and according to this principle, the "proximal end" and "distal end" of any component of the medical device or the delivery system are defined. "Axial" generally refers to the length direction of the medical device when being delivered, and "radial" generally refers to the direction of the medical device that is perpendicular to the "axial" direction, and according to this principle, the "axial" and "radial" directions of any component of the medical device are defined.

[0068] In an embodiment, as Figure 1As shown in the diagram, the delivery system of the present invention delivers the annular device to the coronary sinus-greater cardiac vein. The device enters the body via the jugular vein and is implanted into the coronary sinus-greater cardiac vein. The annular device 100 has two anchoring elements: a distal anchor 112 anchored at the greater cardiac vein 810, and a proximal anchor 111 anchored at the coronary sinus 820, connected by a connecting rod 160. By tightening the annular device 100, inward pressure is applied to the mitral valve annulus 850, causing the mitral valve annulus 850 to contract and essentially restore its normal geometry, thereby ensuring a tight closure of the mitral valve leaflets and improving mitral valve regurgitation.

[0069] The distal anchor 112 of the annular device 100 is provided with a limiting ring 121, and the proximal anchor 111 is provided with a limiting ring 122. During the delivery of the implant to the target position, the limiting rings 121 and 122 are not locked into the limiting portions 131 and 132, and the distal anchor 112 and proximal anchor 111 are in a non-stable state, which facilitates pushing. When the implant is delivered to the target position, after the distal anchor 112 and proximal anchor 111 are released, the limiting rings 121 and 122 are locked into the limiting portions 131 and 132 (the distal anchor limiting ring 122 is locked into the distal limiting portion 131, and the proximal anchor limiting ring 121 is locked into the proximal limiting portion 132), and the distal anchor 112 and proximal anchor 111 are in a stable state, firmly anchored in the blood vessel. When the surgery does not go smoothly and the implant needs to be retrieved, the distal anchor limiting ring 122 and the proximal anchor limiting ring 121 are controlled to disengage from the limiting part 131 and the limiting part 132 by the distal pull rope and the proximal pull rope, so that the distal anchor 112 and the proximal anchor 111 return to the unstable state, which facilitates retrieval.

[0070] In one implementation, such as Figure 2 As shown in the diagram, the annular retraction device in the conveying system of the present invention includes a near-end anchor 111 and a far-end anchor 112. A near-end anchor limiting ring 121 is provided on one side of the near-end anchor 111, and a far-end anchor limiting ring 122 is provided on one side of the far-end anchor 112. Sleeves 150 are respectively provided in the near-end anchor 111 and the far-end anchor 112, and a connecting rod 160 is provided between the near-end anchor 111 and the far-end anchor 112. The far-end anchor limiting ring 122 is engaged with the far-end limiting part 131, and the near-end anchor limiting ring 121 is engaged with the near-end anchor limiting part 132.

[0071] The conveying system can also unlock the ring-shrinking device. The far end pull rope 440 is connected to the far end anchor limit ring 122 along the core wire 450, and the near end pull rope 430 is connected to the near end anchor limit ring 121 along the core wire 450. In the far end direction, the core wire 450 extends into and is locked into the sleeve 150.

[0072] In one implementation, such as Figure 3As shown, in the delivery system of the present invention, the annular device in the coronary sinus-greater cardiac vein is in an expanded state. Under the delivery and pushing of the push rod 300 and the delivery sheath 200, the annular device is placed at the target position, and the distal anchor 112 and the proximal anchor 111 are in an expanded state in the coronary sinus-greater cardiac vein.

[0073] In one implementation, such as Figure 4 As shown, the conveying system of the present invention has a connection relationship at the far end of the retracting device. At the far end of the retracting device, the core wire 450 passes through the far end anchor limiting ring and the far end pull rope 440, extends into the far end sleeve 150, and is pressed into the sleeve 150. A through-ring is provided at the far end of the far end pull rope 440, so that the far end pull rope 440 is securely connected to the far end anchor. When the retracting device needs to be repositioned, under the traction of the far end pull rope 440, the far end anchor limiting ring of the retracting device disengages from the far end limiting part, completing the far end unlocking of the retracting device. After the repositioning of the retracting device is completed, at the far end of the retracting device, under the control of the operation control component, the core wire 450 disengages from the sleeve 150 and exits the conveying system. Since the far end pull rope 440 has disengaged from the far end anchor limiting ring, it exits the conveying system under the control of the operation control component. When the retracting device is retrieved, the unlocking is performed at the far end of the retracting device according to the steps described above.

[0074] In one implementation, such as Figure 5 As shown, the delivery sheath 200 in the delivery system of the present invention is connected to the loader in a certain way. The delivery sheath 200 is composed of three parts: an inner layer, a middle layer and an outer layer. The inner layer can be a 10F sheath with an inner diameter of about 2.5 mm. The inner layer uses a polymer material with a very low coefficient of friction, such as a PTFE membrane (polytetrafluoroethylene membrane). The middle layer can be a medical interventional grade metal braided mesh tube, such as 304V stainless steel. The outer layer can be a polymer material with good bending resistance, such as Pebax material (polyether block polyamide). The tail end of the delivery sheath 200 is connected to a Y valve. Both outlets of the Y valve are male Luer connectors.

[0075] The loader 600 is used to load the implant. The inner diameter of the loader 600 is the same as the inner diameter of the delivery sheath 200. The external thread of the loader 600 is connected to the internal thread of the delivery handle loader knob. The distal end of the loader 600 is a female Luer connector, which can be connected to the male Luer connector of the Y valve of the delivery sheath 200.

[0076] In one implementation, such as Figure 6 As shown in the figure, the loader pre-installed with the retractable device in the conveying system of the present invention is a cross-sectional view. The retractable device in the retracted state is pre-installed into the inner cavity of the transfer device. The push rod 300 and the connecting pipe 700 extend into the proximal end of the loader to push the retractable device in the retracted state toward the distal end. After passing through the conveying sheath, the retractable device is finally pushed to the target position.

[0077] In an embodiment, as shown in Figure 7 The push rod 300 and the push rod fixing member 511 in the delivery system of the present application, the inner diameter of the push rod fixing member 511 matches the outer diameter of the push rod 300, and the proximal end of the push rod 300 passes through and is fixed in the push rod fixing member 511. One end of the push rod fixing member 511 is provided with a limiting structure which slides in the matching groove of the shell but cannot rotate, so that under the action of the limiting structure of the push rod fixing member 511, the push rod 300 can only move in the axial direction.

[0078] The outer diameter of the push rod fixing member 511 is provided with a thread which matches the inner thread of the push rod control knob device.

[0079] In an embodiment, as shown in Figure 8 The inner diameter of the push rod fixing member 511 matches the outer diameter of the push rod 300, and the push rod passes through the inner hole of the push rod fixing member and can be connected together using glue, Figure 8 The cross-sectional view is shown in Figure 7 .

[0080] In an embodiment, as shown in Figure 9 The push rod can be a multi-lumen tube made of medical intervention high polymer material, such as polyethylene PE; wherein the middle large lumen 311 of the push rod matches the connecting tube, and the diameter of the large lumen 311 is about 0.5 mm larger than the outer diameter of the connecting tube, so as to ensure that the connecting tube can move in the push rod; there are three small lumens in the push rod, two small lumens 313 and 314 are used for passing through the proximal pull cord and the distal pull cord, and the other small lumen 312 is used for passing through the core wire, and the push rod is provided with multiple lumens, which can avoid the winding of the distal pull cord, the proximal pull cord and the core wire together during the pushing process and the recovery process of the implant, Figure 9 The local enlarged view is shown in Figure 7 .

[0081] The large lumen 311 in the push rod through the connecting tube can be provided with an inner chamfer, which facilitates the entry of the proximal limiting part into the large lumen 311.

[0082] In an embodiment, as shown in Figure 10 The delivery system of the present application has a connection relationship at the proximal end of the ring shrink device, the connecting wire 410 passes through from the inner side of the proximal limiting part 132, the lining wire 420 passes through between the connecting wire 410 and the proximal limiting part 132, and the connecting wire 410 and the proximal limiting part 132 are connected together. The connecting wire 410 and the lining wire 420 pass through the middle of the connecting tube 700, the connecting wire 410 is tensioned, the proximal limiting part 132 is tightly attached to the connecting tube 700, and the connection between the implant device and the delivery system is stable.

[0083] The liner wire 420 passes through the connecting wire 410 and the proximal end limiting part 132, one end of the liner wire 420 is inserted into the proximal end anchor sleeve, the other end of the liner wire 420 is connected to the liner wire fixing part after passing through the push rod 300, the liner wire fixing part is rotationally fixed on the distal end screw, the liner wire fixing part controls the liner wire to retreat, and the connecting wire 410 and the proximal end limiting part 132 will be disconnected.

[0084] The front end of the connecting pipe 700 can use a processed metal pipe with good flexibility, such as a spring pipe or a snake pipe, and the rear end of the connecting pipe 700 uses a metal pipe without special processing and with good pushability, such as a stainless steel pipe or a hypotube.

[0085] In an embodiment, as shown in Figure 11 , the proximal end limiting part 132 is arrow-shaped, wherein the "arrow-shaped" of the proximal end limiting part 132 points to the connecting pipe, the proximal end limiting part 132 can abut against the connecting pipe to ensure that the ring shrinkage device is stably connected with the delivery system; when the ring shrinkage device is recovered and repositioned, the proximal end limiting part 132 can smoothly enter the push rod, and the proximal end of the ring shrinkage device can be unlocked smoothly, wherein Figure 11 is Figure 10 a partial enlarged view.

[0086] In an embodiment, as shown in Figure 12 , the connection relationship of the delivery system of the present application at the proximal end of the ring shrinkage device is shown from another perspective, the proximal end limiting part 132 can also be provided with other structures that are conducive to stable abutment with the connecting pipe or other structures that are conducive to the smooth entry of the proximal end limiting part 132 into the push rod cavity, such as

[0087] Figure 12 It is also shown that at the proximal end of the ring shrinkage device, the proximal end pull rope 430 is connected with the proximal end anchor limiting ring 121 along the core wire 450, when the ring shrinkage device is recovered or repositioned, at the proximal end of the ring shrinkage device, under the traction of the proximal end pull rope 430, the proximal end anchor limiting ring 121 can be separated from the proximal end limiting part 132, and the proximal end of the ring shrinkage device is unlocked.

[0088] In an embodiment, as shown in Figure 13 , the connection relationship of the connecting pipe of the delivery system of the present application and the ring shrinkage device is shown, the proximal end limiting part 132 is provided with structures that are conducive to stable abutment with the connecting pipe or structures that are conducive to the smooth entry of the proximal end limiting part 132 into the push rod cavity, such as an oval shape or an olive shape.

[0089] In an embodiment, as shown in Figure 14As shown, the connecting tube 700 in the delivery system of the present application and the connecting tube fixing member 521, the connecting wire 410 and the lining wire 420 are arranged in the connecting tube 700, the connecting tube 700 is fixed in the connecting tube fixing member 521, the connecting tube fixing member 521 is further provided with a connecting wire fixing part, after the connecting wire is fixed, under the traction of the connecting wire, the proximal end limiting part 132 is close to the connecting tube 700, which ensures the stable connection of the implant device and the delivery system; the lining wire 420 is connected to the lining wire fixing member at the proximal end after passing through the connecting tube 700.

[0090] In an embodiment, as shown in Figure 15 , the connecting wire 410 is reversely bent at the distal end, and the lining wire 420 passes through the reversely bent part of the connecting wire 410, Figure 15 , which is a partial enlarged view. Figure 14

[0091] In an embodiment, as shown in Figure 16 , the operation control assembly 500 in the delivery system of the present application, in the shell composed of the upper cover 571 and the lower cover 572 of the delivery handle, is provided with a loader control part 560 and a push rod controller 513, wherein the loader control part 560 is threadedly connected with the loader, the loader control part 560 controls the release of the distal end anchor of the ring shrink device in the delivery sheath through the control of the loader, and the distal end anchor limiting ring is clamped into the distal end limiting part through the delivery sheath, and the superior vena cava is expanded after the distal end anchor is locked, as shown in Figure 17 .

[0092] In an embodiment, the loader control part 560 controls the release of the proximal end anchor of the ring shrink device in the delivery sheath through the control of the loader.

[0093] In an embodiment, the push rod controller 513 pushes the proximal end anchor limiting ring in the distal end direction through the control of the push rod, until the proximal end anchor limiting ring is clamped into the proximal end limiting part, and the anchoring of the proximal end anchor in the blood vessel is completed, as shown in Figure 3 .

[0094] In an embodiment, as shown in Figure 16 ​As shown, in the shell formed by the upper cover 571 and the lower cover 572 of the delivery handle, a first pull rod / near-end anchor pull rod 541, a second pull rod / far-end anchor pull rod 542 and a second guide / pull rod guide 543, a second guide / pull rod guide 544 are arranged, wherein the first pull rod / near-end anchor pull rod 541 is connected with the near-end pull rope, the second pull rod / far-end anchor pull rod 542 is connected with the far-end pull rope, the first pull rod / near-end anchor pull rod 541 slides in the second guide / pull rod guide 543, so as to pull the near-end pull rope to move axially, and provide pulling force for unlocking the near-end anchor of the ring shrink device; the second pull rod / far-end anchor pull rod 542 slides in the second guide / pull rod guide 544, so as to pull the far-end pull rope to move axially, and similarly, provide pulling force for unlocking the far-end anchor of the ring shrink device.

[0095] In an embodiment, as shown in Figure 18 A fixing boss 553 is arranged in the first pull rod / near-end anchor pull rod 541 and the second pull rod / far-end anchor pull rod 542 respectively, and a fixing groove 554 is arranged in the first guide / pull rod guide 543 and the second guide / pull rod guide 544 respectively, wherein the fixing boss 553 can be stably fixed in the fixing groove 554, so that when the first pull rod / near-end anchor pull rod 541 is connected with the near-end pull rope, the first pull rod / near-end anchor pull rod 541 pulls the near-end pull rope to move axially, and can be stably fixed in a position in the axial direction; when the second pull rod / far-end anchor pull rod 542 is connected with the far-end pull rope, the second pull rod / far-end anchor pull rod 542 pulls the far-end pull rope to move axially, and can also be stably fixed in a position in the axial direction.

[0096] In an embodiment, as shown in Figure 19 A first position 551 and a second position 552 are arranged in the second guide / pull rod guide 543, and similarly, a first position 551 and a second position 552 are arranged in the second guide / pull rod guide 544. Figure 19 The state that the first pull rod / near-end anchor pull rod 541 is in the first position 551 and the state that the second pull rod / far-end anchor pull rod 542 is in the first position 551 are shown.

[0097] It is easy to understand that the near-end anchor pull rod 541 and the far-end anchor pull rod 542 in the delivery system of the present application are in the first position 551 of the pull rod guide 543 and the pull rod guide 544, at this time, the far-end anchor and the near-end anchor of the ring shrink device are both in the unlocking state.

[0098] In an embodiment, as shown in Figure 20As shown, the first position 551 and the second position 552 are arranged in the second guide member / rod guide member 543, and the first position 551 and the second position 552 are arranged in the second guide member / rod guide member 544 as well. Figure 20 As shown, the first position 551 and the second position 552 are arranged in the second guide member / rod guide member 543, and the first position 551 and the second position 552 are arranged in the second guide member / rod guide member 544 as well.

[0099] It is easy to understand that the proximal anchor rod 541 and the distal anchor rod 542 in the delivery system of the present application are in the second position 552 of the rod guide member 543 and the rod guide member 544, at this time, the distal anchor and the proximal anchor of the ring shrink device are both in the locked state.

[0100] In an embodiment, as shown in Figure 21 , a state of operation of the proximal anchor rod 541 and the distal anchor rod 542 in the delivery system of the present application is shown, at the proximal end of the shell formed by the upper cover of the delivery handle and the lower cover of the delivery handle, the proximal anchor rod 541 is in the first position in the second guide member, the proximal anchor limiting ring is separated from the proximal limiting part, the proximal anchor of the ring shrink device is in the unlocked state; the distal anchor rod 542 is in the second position in the second guide member, the distal anchor limiting ring is clamped into the proximal limiting part, the distal anchor of the ring shrink device is in the locked state.

[0101] In an embodiment, as shown in Figure 22 , a cross-sectional view of the operation control assembly in the delivery system of the present application is shown, at the proximal end of the shell formed by the upper cover of the delivery handle and the lower cover of the delivery handle, the first guide member / mandrel is led out from the proximal end of the cavity of the push rod, passes through the third guide member / mandrel guide member 451, and is connected with the first guide member fixing part / mandrel fixing part 531, the stopper 534 can prevent the relative movement between the first guide member fixing part / mandrel fixing part 531 and the tail end screw; the first traction member / connection wire is led out from the proximal end of the inner cavity of the connecting tube 700, and is connected with the first traction member fixing part / connection wire fixing part arranged on the connecting member fixing part 521; the second traction member / liner wire is led out from the proximal end of the inner cavity of the connecting tube 700, and is connected with the second traction member fixing part / liner wire fixing part 523, the second traction member fixing part / liner wire fixing part 523 is provided with a stopper 534 for preventing the relative movement between the second traction member fixing part / liner wire fixing part 523 and the tail end screw.

[0102] It is easy to understand that in the operation control assembly provided by the present application, the first guide member / mandrel, the first traction member / connection wire and the second traction member / liner wire can be fixed and controlled respectively, so that the unlocking and recovery of the distal ring shrink device can be operated through the operation control assembly.

[0103] In an embodiment, as shown in Figure 23Figure 6 shows the split connection pipe fixing member 521 and the tail end screw 524 in the delivery system of the present application; wherein the connection pipe fixing member 521 is connected to the tail end screw 524 in a quick connection manner.

[0104] In one embodiment, as shown in Figure 24 and Figure 25 Figure 6 shows the split connection pipe fixing member 521 and the tail end screw 524 in the delivery system of the present application; wherein the connection pipe fixing member 521 is connected to the tail end screw 524 in a quick connection manner. Figure 24 and Figure 25 As shown in Figures 6 and 7, the second traction member fixing portion / liner fixing portion 523 and the first guide member fixing portion / core wire fixing portion 531 are both provided with a groove structure 533, which cooperates with a stopper 534 to prevent the second traction member fixing portion / liner fixing portion 523 and the first guide member fixing portion / core wire fixing portion 531 from rotating relative to the tail end screw.

[0105] The following is further elaborated through specific embodiments.

[0106] Embodiment 1

[0107] In this embodiment, the delivery system is provided for delivering the ring shrink device 100 to the target location, the ring shrink device 100 comprising an anchor body 110 and a limiting portion 131, 132, wherein a proximal end anchor limiting ring 121 and a distal end anchor limiting ring 122 are arranged on one side of the anchor body 110.

[0108] The delivery system comprises: a delivery sheath 200, the inner cavity of the delivery sheath 200 being a channel for delivering the ring shrink device 100 to the target location; a loader 600, the loader 600 being used for preloading the ring shrink device 100, the distal end of the loader 600 being connected to the proximal end of the delivery sheath 200; a push rod 300, the push rod 300 having a plurality of independent through cavities 310, the push rod 300 being used for pushing the ring shrink device 100 in the delivery sheath 200, and the distal end opening of the cavity 310 of the push rod 300 being provided with an inner chamfer.

[0109] An operation control assembly 500, the operation control assembly 500 being used for pushing the anchor body 110 to the target location, and for clamping or disengaging the limiting ring 121 from the limiting portion 132, and for clamping or disengaging the limiting ring 122 from the limiting portion 131, by controlling the delivery sheath 200, the push rod 300 and the traction assembly 400.

[0110] The operation control assembly 500 comprises a loader control part 560, which controls the axial movement of the delivery sheath 200 by controlling the loader 600; the operation control assembly 500 further comprises a push rod fixing part 511 and a push rod controller 513, wherein the push rod fixing part 511 is fixedly connected with the push rod 300, and the push rod controller 513 controls the axial movement of the push rod 300 in the delivery sheath 200 by controlling the push rod fixing part 511; wherein the push rod fixing part 511 is provided with a limiting structure 512, and the push rod 300 moves only in the axial direction under the action of the limiting structure 512.

[0111] The delivery system further comprises a traction assembly 400, which is connected with the ring shrink device 100 after passing through the cavity 310; the traction assembly 400 comprises a first traction part 410, a second traction part 420, a third traction part 430, a fourth traction part 440, and a first guide part 450; wherein the first traction part 410 and the second traction part 420 are used for traction of the limiting part 132; wherein the first traction part 410 and the second traction part 420 pass through one cavity 310 of the push rod 300 to the distal end of the push rod 300, and the first traction part 410, the second traction part 420 and the limiting part 132 are connected in a detachable manner; under the action of the traction force provided by the second traction part 420, the first traction part 410, the second traction part 420 and the limiting part 132 are loosened; wherein the first guide part 450 is arranged along the axis direction of the cavity and is detachably connected with the distal end of the ring shrink device 100; wherein the third traction part 430 is connected with the limiting ring 121 along the first guide part 450, and under the action of the third traction part 430, the limiting ring 121 can be separated from the limiting part 132; the fourth traction part 440 is connected with the limiting ring 122 along the first guide part 450, and under the action of the fourth traction part 430, the limiting ring 122 can be separated from the limiting part 131.

[0112] The delivery system further comprises a connecting tube 700, the outer diameter of the connecting tube 700 matches the cavity 310, and the first traction part 410 and the second traction part 420 pass through the inner cavity of the connecting tube 700; wherein under the joint action of the first traction part 410 and the second traction part 420, the proximal limiting part 132 of the ring shrink device 100 abuts against the distal tube port of the connecting tube 700.

[0113] The operation of the delivery system in the embodiment on the delivery process of the ring shrink device is as follows:

[0114] After the implant is connected with the handle of the delivery system of the present application, the implant is compressed to the inner diameter size of the loader and is inserted into the loader for preloading, as shown in Figure 6

[0115] ​The delivery sheath 200 reaches the release position of the implant along the blood vessel, and then is connected with the loader 600. One hand holds the delivery sheath 200, and the other hand holds the push rod 300 of the handle and pushes it towards the heart. When the push rod 300 is fully pushed into the loader 600, the delivery sheath 200 is screwed with the loader 600. When the loader 600 contacts with the loader control part 560 of the handle, the implant is just pushed to the farthest end of the delivery sheath 200, as shown in Figure 5 .

[0116] The loader control part 560 is rotated clockwise, and the implant releases the distal anchor of the anchor body from the delivery sheath 200. At this time, the distal anchor is released in the unlocked state. The loader control part 560 is counterclockwise, and the delivery sheath 200 pushes the distal anchor limiting ring 122 into the distal limiting part 131. After the distal anchor is locked, the superior vena cava is enlarged, as shown in Figure 17 .

[0117] The loader control part 560 is continuously rotated clockwise, and the delivery sheath 200 is paused when it approaches the proximal anchor. The delivery handle is pulled back at this time, and the mitral annulus is contracted. The state of the mitral annulus is maintained.

[0118] The loader control part 560 is continuously rotated clockwise, and the proximal anchor is released. After the proximal anchor is released, it is in the unlocked state. The push rod controller 513 is counterclockwise, and the push rod 300 pushes the proximal anchor limiting ring 121 forward. The proximal anchor limiting ring 121 is pushed into the distal limiting part 131 and locked, and the proximal anchor is anchored in the blood vessel, as shown in Figure 3 .

[0119] After confirming that the implant is released in place, the safety knob is unscrewed, the core wire fixing part is unscrewed, the core wire is retracted, the distal pull rope and the proximal pull rope are disconnected with the implant. The liner fixing part is unscrewed, the liner is retracted, the proximal limiting part 132 of the implant is disconnected with the delivery system, and the implant is released.

[0120] The operation of the delivery system in the embodiment on the recovery process of the contraction device is as follows:

[0121] When the implant is not successfully released and needs to be recovered, the proximal anchor pull rod 541 is pulled back first without pulling out the core wire and the liner. The proximal anchor limiting ring 121 is pulled out of the proximal limiting part 132, and the fixed boss 553 is clamped in the fixed groove 554 of the pull rod guide, as shown in Figure 21 .

[0122] The loader control part 560 is rotated counterclockwise, the delivery sheath 200 is advanced, and the proximal anchor is accommodated into the delivery sheath 200; then the distal anchor pull rod 542 is pulled backward, the distal anchor limiting ring 122 is pulled out of the distal limiting part 131, and the fixed boss 553 is clamped in the pull rod guide groove 533 by rotating the distal anchor pull rod 542; then the loader control part 560 is rotated counterclockwise, the delivery sheath 200 is advanced, and the distal anchor is accommodated into the delivery sheath 200; and the implant recovery is completed.

[0123] Embodiment 2

[0124] The difference between this embodiment and the above embodiments is that the limiting part 132 and the distal end of the first traction member 410 partially overlap each other, and a through hole is formed in the overlapping area, the second traction member 420 passes through the through hole and is press-connected with the anchor body 110, and the limiting part 132 has an outer shape abutting against the distal end opening of the connecting tube 700, wherein at least the radial dimension of the limiting part 132 decreases from the distal end to the proximal end.

[0125] Embodiment 3

[0126] The difference between this embodiment and the above embodiments is that the operation control assembly 500 further comprises a connecting tube fixing member 521 connected with the proximal end of the connecting tube 700, wherein a first traction member fixing part 522 is arranged on the connecting tube fixing member 521; under the action of the operation control assembly 500, the connecting tube fixing member 521 drives the connecting tube 700 to move only in the axial direction in the cavity 310 of the push rod.

[0127] By arranging the first traction member fixing part 522, the first traction member can be stably connected with the ring shrinking device under the condition of providing traction, thereby ensuring the stability of the entire delivery system.

[0128] Embodiment 4

[0129] The difference between this embodiment and the above embodiments is that the operation control assembly 500 comprises a tail end screw 524 and a second traction member fixing part 523, the second traction member fixing part 523 is threadedly connected with the tail end screw 524; the connecting tube fixing member 521 and the tail end screw 524 are integrated, or the connecting tube fixing member 521 and the tail end screw 524 are connected in a quick connection manner; the second traction member fixing part 523 is provided with a plurality of groove structures 533, and a stopper 534 is arranged in the groove structure 533, for preventing the relative movement between the second traction member fixing part 523 and the tail end screw 524.

[0130] When the connecting tube fixing member and the tail end screw are integrated, the number of parts is reduced, and the cost is reduced; when the connecting tube fixing member and the tail end screw are separate, in order to facilitate assembly, a quick release structure can be used to connect the connecting tube fixing member and the tail end screw together.

[0131] Embodiment 5

[0132] The difference between this embodiment and the above-mentioned embodiments is that the operation control assembly 500 comprises a first guide piece fixing part 531 and a tail fixing end 532, and the first guide piece fixing part 531 and the tail fixing end 532 are connected in a threaded manner; the first guide piece fixing part 531 is provided with a plurality of groove structures 533, and a stopper 534 is arranged in the groove structure 533, which is used to prevent the relative movement of the first guide piece fixing part 531 and the tail fixing end 532.

[0133] The tail of the first guide piece fixing part 531 is designed as a groove structure, and the front end of the tail end screw is provided with a stopper 534, which can be quickly assembled into the groove structure, thereby playing an insurance role on the first guide piece fixing part 531, preventing it from rotating due to accidents and causing the movement of the core wire.

[0134] Embodiment 6

[0135] The difference between this embodiment and the above-mentioned embodiments is that the operation control assembly 500 comprises a first pull rod 541 and a second pull rod 542, and second guide pieces 543 and 544, the first pull rod 541 slides along the second guide piece 543, and the second pull rod 542 slides along the second guide piece 544; wherein the first pull rod 541 is connected with the third traction piece 430, and the second pull rod 542 is connected with the fourth traction piece 440, the first position 551 and the second position 552 are arranged in the second guide piece 543, and the first position 551 and the second position 552 are also arranged in the second guide piece 544, wherein the first pull rod 541 slides between the first position 551 and the second position 552 along the second guide piece 543, and the second pull rod 542 slides between the first position 551 and the second position 552 along the second guide piece 544.

[0136] The handle of the delivery system provided by the application can control the proximal pull rope and the distal pull rope by operating the first pull rod and the second pull rod, and finally control the distal anchor limiting ring and the proximal anchor limiting ring.

[0137] The above-mentioned embodiments only express several embodiments of the application, and the description is more specific and detailed, but it cannot be understood as a limitation on the scope of the patent. It should be noted that for ordinary skilled persons in the art, without departing from the concept of the application, a number of modifications and improvements can be made, which are all within the protection scope of the application. Therefore, the protection scope of the patent of the application should be subject to the appended claims.

Claims

1. A conveying system suitable for conveying a retractable device (100) to a target location, characterized in that, The annular contraction device (100) includes an anchor body (110) and limiting portions (131, 132) provided at both ends of the anchor body, wherein limiting rings (121, 122) are respectively provided at both ends of the anchor body (110). The conveying system includes: A delivery sheath (200) has an inner cavity that serves as a channel for delivering the annular device (100) to the target location; A push rod (300) having multiple independently penetrating cavities (310) pushes the annular device (100) in the delivery sheath (200); A traction assembly (400) passes through the cavity (310) and is connected to the annular device (100); An operation control component (500) controls the delivery sheath (200), the push rod (300), and the traction component (400) to push the anchor body (110) to the target position and to engage or disengage the limiting rings (121, 122) from the limiting parts (131, 132). The traction assembly (400) includes a first traction member (410) and a second traction member (420). The first traction member (410) and the second traction member (420) are used to pull the limiting part (132). The limiting part (132) partially overlaps with the distal end of the first traction member (410) and forms a through hole in the overlapping area. The second traction member (420) passes through the through hole and is pressed against the anchor body (110). The traction assembly (400) includes a third traction member (430) and a fourth traction member (440), as well as a first guide member (450), which is arranged along the axial direction of the cavity and is detachably connected to the distal end of the annular device (100). The third traction member (430) is connected to the limiting ring (121) along the first guide member (450), and under the action of the third traction member (430), the limiting ring (121) can disengage from the limiting part (132); The fourth traction member (440) is connected to the limiting ring (122) along the first guide member (450), and under the action of the fourth traction member (440), the limiting ring (122) can disengage from the limiting part (131).

2. The conveying system according to claim 1, characterized in that, The first traction member (410) and the second traction member (420) extend through a cavity (310) of the push rod (300) to the distal end of the push rod (300), and the first traction member (410), the second traction member (420) and the limiting part (132) are detachably connected.

3. The conveying system according to claim 2, characterized in that, The conveying system further includes a connecting pipe (700) whose outer diameter matches the cavity (310), and the first traction member (410) and the second traction member (420) pass through the inner cavity of the connecting pipe (700). Under the combined action of the first traction member (410) and the second traction member (420), the proximal limiting part (132) of the annular shrinkage device (100) abuts against the distal end of the connecting pipe (700).

4. The conveying system according to claim 3, characterized in that, The limiting portion (132) has a shape that abuts against the distal opening of the connecting tube (700), wherein at least the radial dimension of the limiting portion (132) decreases from the distal end to the proximal end.

5. The conveying system according to claim 1, characterized in that, The operation control component (500) includes a first guide fixing part (531) and a tail fixing end (532), which are threadedly connected.

6. The conveying system according to claim 1, characterized in that, The operation control assembly (500) includes a first pull rod (541) and a second pull rod (542), as well as a second guide (543, 544), the second guide (543, 544) having a first position (551) disposed at the proximal end and a second position (552) disposed at the distal end; The first pull rod (541) is connected to the third traction member (430), and the second pull rod (542) is connected to the fourth traction member (440). The first pull rod (541) and the second pull rod (542) slide along the second guide member (543, 544) and switch between the first position (551) and the second position (552).

7. The conveying system according to any one of claims 1-4, characterized in that, The operation control assembly (500) further includes a push rod fixing member (511) and a push rod controller (513), wherein the push rod fixing member (511) is fixed to the push rod (300), and the push rod controller (513) is connected to the push rod fixing member (511) and controls the axial movement of the push rod (300) in the delivery sheath (200) through the push rod fixing member (511).

8. The conveying system according to claim 7, characterized in that, The near end of the push rod fixing member (511) is provided with a T-shaped boss structure (512), which moves only axially within the groove that it mates with.

9. The conveying system according to claim 4, characterized in that, The operation control assembly (500) further includes a connecting tube fixing member (521), which is connected to the proximal end of the connecting tube (700). The connecting pipe fixing part (521) is provided with a first traction member fixing part (522), which is used to fix the first traction member.

10. The conveying system according to claim 9, characterized in that, The operation control component (500) includes a tail screw (524) and a second traction member fixing part (523). The second traction member fixing part (523) is threadedly connected to the tail screw (524), and the second traction member fixing part (523) is used to fix the second traction member.

11. The conveying system according to claim 10, characterized in that, The connecting pipe fixing component (521) and the tail screw (524) are an integral structure, or the connecting pipe fixing component (521) and the tail screw (524) are connected in a detachable manner.

12. The conveying system according to claim 10, characterized in that, The second traction member fixing part (523) is provided with a plurality of groove structures (533), and a stop (534) is provided in the groove structure (533) to prevent relative movement between the second traction member fixing part (523) and the tail end screw (524).

13. The conveying system according to claim 5, characterized in that, The first guide fixing part (531) is provided with a plurality of groove structures (533), and a stop (534) is provided in the groove structure (533) to prevent relative movement between the first guide fixing part (531) and the tail fixing end (532).

14. The conveying system according to any one of claims 1-6, characterized in that, The conveying system also includes a loader (600) for pre-loading the annular device (100), the distal end of the loader (600) being connected to the proximal end of the conveying sheath (200); The operation control assembly (500) further includes a loader control unit (560) connected to the loader (600) and controlling the axial movement of the delivery sheath (200) through the loader (600).

Images