A temperature monitoring based transcatheter ultrasound control method and system

Abstract

The application provides a temperature monitoring based transcatheter ultrasonic control method and system, relates to the technical field of medical devices, and an ultrasonic module controls an ultrasonic excitation circuit to emit ultrasonic pulse energy according to preset control parameters, an ultrasonic transducer generates ultrasonic sound waves under the ultrasonic pulse energy, and a temperature acquisition module acquires temperature information of the ultrasonic transducer in the process of generating the ultrasonic sound waves; a control module compares the temperature information with a preset threshold value, controls the ultrasonic module to stop working, or controls the ultrasonic excitation circuit to emit adjusted ultrasonic pulse energy based on adjusting the control parameters. The application achieves the technical effect that the real-time temperature condition of the transcatheter treatment transducer is fed back in time, and the pulse energy emitted by the ultrasonic excitation circuit is adaptively adjusted, so that efficient treatment is provided for the patient in the state of ensuring the safety of the equipment.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a trans-catheter ultrasound control method and system based on temperature monitoring. BACKGROUND

[0002] Ultrasound waves are suitable for application in medical fields such as ultrasound imaging due to their mechanical effect, ultrasonic cavitation effect, thermal effect and other effects. Meanwhile, ultrasound has better safety compared to CT imaging and other imaging methods. Due to diseases or physical reasons, blood clots and other diseases are prone to form at blood vessels. Current thrombolysis treatment methods include catheter-directed thrombolysis (CDT), which has the problems of large required drug dosage and high risk of bleeding; and mechanical thrombolytic therapy (PMT), which has the characteristics of high thrombolysis efficiency, but mechanical thrombolysis is prone to damage blood vessel walls and cause risks such as hemolysis. With the development of technology, an ultrasound-assisted thrombus dissolution device has been developed, and trans-catheter interventional therapy is a new type of treatment method for current clinical thrombotic diseases, which uses the cavitation effect of ultrasound waves to tear and dissolve blood clots. During the ultrasonic cavitation process, in addition to the cavitation effect, the ultrasonic transducer also generates heat during operation, and excessive temperature may damage blood and human tissues, affecting the safety of patients, so it is necessary to monitor the change of the temperature around the ultrasonic transducer in real time and adjust the parameters to maintain the working temperature without affecting the function of the patient's body tissue.

[0003] The prior art has the technical problem that the ultrasonic transducer control parameters are not well adapted to the patient's body tissue condition, resulting in poor treatment effect on the patient's condition. SUMMARY

[0004] The present application provides a trans-catheter ultrasound control method and system based on temperature monitoring, which is used to solve the technical problems in the prior art that the temperature is too high during the ultrasonic treatment process, which may cause damage to the human body, and the ultrasonic transducer control parameters are not well adapted to the patient's body tissue condition, resulting in poor treatment effect on the patient's condition.

[0005] In view of the above problems, the present application provides a trans-catheter ultrasound control method and system based on temperature monitoring.

[0006] In a first aspect of the present application, a temperature monitoring based transcatheter ultrasound control method is provided, which comprises: the control module receiving an instruction issued by a user, controlling the ultrasound excitation circuit to emit ultrasound pulse energy according to preset control parameters; the ultrasound transducer generating ultrasound sound waves under the ultrasound pulse energy; the temperature acquisition module acquiring temperature information of the ultrasound transducer during the generation of ultrasound sound waves; the control module receiving the temperature information, determining whether the temperature information exceeds a preset threshold, if yes, controlling the ultrasound module to stop working, if not, inputting the temperature information into a pre-constructed ultrasound control information space to obtain an adjustment control parameter; and the ultrasound module controlling the ultrasound excitation circuit to emit an adjusted ultrasound pulse energy according to the adjustment control parameter.

[0007] In a second aspect of the present application, a temperature monitoring based transcatheter ultrasound control system is provided, which is applied to a temperature monitoring based transcatheter ultrasound control method, and comprises: an ultrasound module, which comprises an ultrasound excitation circuit and an ultrasound transducer, and works under the instruction of a user to emit ultrasound pulse energy, and the ultrasound transducer generates ultrasound sound waves under the ultrasound pulse energy; a temperature acquisition module, which is connected to the ultrasound module through a CAN bus with a control module, and is used to acquire temperature information of the ultrasound transducer; and a control module, which is used to receive the temperature information, determine whether the temperature information exceeds a preset threshold, if yes, control the ultrasound module to stop working, if not, input the temperature information into a pre-constructed ultrasound control information space to obtain an adjustment control parameter, and control the ultrasound module to control the ultrasound excitation circuit to emit an adjusted ultrasound pulse energy according to the adjustment control parameter; wherein the temperature acquisition module comprises a thermocouple differential signal filtering module, a thermocouple digital conversion circuit and a temperature acquisition control circuit, the thermocouple differential signal filtering module is used to acquire a first signal of a thermocouple, perform differential analog processing to obtain a differential analog signal, and send the differential analog signal to the thermocouple digital conversion circuit, the thermocouple digital conversion circuit receives and converts the differential analog signal to obtain the temperature information, and sends the temperature information to the temperature acquisition control circuit, the temperature acquisition control circuit receives the temperature information and sends the temperature information to the control module, and the thermocouple is arranged side by side with the ultrasound transducer.

[0008] In a third aspect of the present application, a temperature monitoring based transcatheter ultrasound control system is provided, characterized in that the system comprises: an instruction receiving processing module configured to control a module to receive an instruction issued by a user, and control an ultrasound excitation circuit to emit ultrasound pulse energy according to a preset control parameter; an ultrasound sound wave generation module configured to control an ultrasound transducer to generate ultrasound sound waves under the ultrasound pulse energy; a temperature information acquisition module configured to control a temperature acquisition module to acquire temperature information of the ultrasound transducer during the generation of the ultrasound sound waves; a temperature information judgment module configured to control the module to receive the temperature information, judge whether the temperature information exceeds a preset threshold, if yes, control the ultrasound module to stop working, and if no, input the temperature information into a pre-constructed ultrasound control information space to obtain an adjustment control parameter; and a control parameter adjustment module configured to control the ultrasound module to control the ultrasound excitation circuit to emit adjusted ultrasound pulse energy according to the adjustment control parameter.

[0009] In a fourth aspect of the present application, a transcatheter ultrasound treatment system is provided, comprising the temperature monitoring based transcatheter ultrasound control system in the second aspect.

[0010] The one or more technical solutions provided in the present application have at least the following technical effects or advantages:

[0011] The method provided by the embodiments of the present application receives an instruction issued by a user through a control module, controls an ultrasound excitation circuit to emit ultrasound pulse energy according to a preset control parameter, controls an ultrasound transducer to generate ultrasound sound waves under the ultrasound pulse energy, controls a temperature acquisition module to acquire temperature information of the ultrasound transducer during the generation of the ultrasound sound waves, controls the control module to receive the temperature information, judges whether the temperature information exceeds a preset threshold, if yes, controls the ultrasound module to stop working, if no, inputs the temperature information into a pre-constructed ultrasound control information space to obtain an adjustment control parameter, and controls the ultrasound module to control the ultrasound excitation circuit to emit adjusted ultrasound pulse energy according to the adjustment control parameter. The real-time temperature condition of the transcatheter treatment transducer is fed back in time. If the temperature reaches the threshold, the ultrasound module will stop working, thereby stopping heat generation and preventing the temperature from further rising. If the temperature does not reach the threshold, it indicates that the system is in a temperature safe range, and the system can still work normally. At this time, the adjustment control parameter can be obtained by inputting the temperature information into the pre-constructed ultrasound control information space. For example, when the temperature is close to the threshold but does not reach the threshold, the working frequency of the ultrasound can be appropriately reduced, or part of the ultrasound transducer can be turned off to reduce heat generation. When the temperature is in a lower state, the working frequency of the transducer can be appropriately increased to strengthen the dissolution of the surrounding thrombus. The present application achieves the technical effect that the real-time temperature of the transcatheter treatment ultrasound transducer is fed back in time, the pulse energy emitted by the ultrasound excitation circuit is adaptively adjusted, the safety of the equipment and the patient is ensured, and efficient treatment is provided for the patient.

[0012] The above description is only a summary of the technical solutions of the present application, in order to more clearly understand the technical means of the present application, and can be implemented according to the content of the specification, and in order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the following specific embodiments of the present application are described. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 A temperature monitoring based transcatheter ultrasound control method provided by the present application is shown in the flow chart;

[0014] Figure 2 The temperature monitoring based transcatheter ultrasound control method provided by the present application is shown in the flow chart for collecting thermocouple temperature information;

[0015] Figure 3 The temperature monitoring based transcatheter ultrasound control method provided by the present application is shown in the flow chart for obtaining adjustment control parameters;

[0016] Figure 4 The temperature monitoring based transcatheter ultrasound control system provided by the present application is shown in the schematic diagram of module connection relationship;

[0017] Figure 5 The temperature monitoring based transcatheter ultrasound control system provided by the present application is shown in the schematic diagram of structure.

[0018] Explanation of reference signs: instruction receiving processing module 11, ultrasonic wave generating module 12, temperature information collecting module 13, temperature information judging module 14, control parameter adjusting module 15. DETAILED DESCRIPTION

[0019] The present application provides a temperature monitoring based transcatheter ultrasound control method and system, which is used to solve the technical problems that the temperature is too high during the ultrasonic treatment process in the prior art, which may cause damage to the human body, and the adaptation of the ultrasonic transducer control parameters to the patient's body tissue condition is not high, resulting in poor treatment effect on the patient's condition. The present application achieves the technical effect that the real-time temperature condition of the transcatheter treatment transducer is fed back in time and the pulse energy emitted by the ultrasonic excitation circuit is self-adaptively adjusted, which ensures the safety of the equipment and provides efficient treatment for the patient.

[0020] In the technical solutions of the present application, the acquisition, storage, use, processing and other data conform to the relevant provisions of national laws and regulations.

[0021] The technical solutions of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. It should be understood that the present invention is not limited to the exemplary embodiments described herein. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention. It should also be noted that, for ease of description, only the parts related to the present invention are shown in the accompanying drawings, not all of them.

[0022] Example 1

[0023] like Figure 1 As shown, this application provides a transcatheter ultrasound control method based on temperature monitoring. The method is applied to a transcatheter ultrasound control system based on temperature monitoring. The system includes an ultrasound module, a temperature acquisition module, and a control module. The ultrasound module includes an ultrasound excitation circuit and an ultrasound transducer. The method includes:

[0024] S100: The control module receives instructions from the user and controls the ultrasonic excitation circuit to emit ultrasonic pulse energy according to preset control parameters;

[0025] S200: The ultrasonic transducer generates ultrasonic sound waves under the ultrasonic pulse energy.

[0026] Specifically, in this embodiment, the user is a surgeon who controls the removal of lesions at specific treatment locations within the patient's blood vessels using an ultrasound transducer. This can be done, for example, during the treatment of DVT, PE, PTS, or during the thermal ablation of tumors or solid tissues, or even during the thermal ablation of nerve tissues. The control module has a human-computer interaction interface with touchscreen or button functionality. Based on the control module, the user inputs preset control parameters for controlling the ultrasound module to emit ultrasound pulse energy via the touchscreen or buttons, and generates instructions.

[0027] The ultrasound module includes an ultrasound excitation circuit and an ultrasound transducer. The ultrasound module receives instructions from the user based on the control module and parses them to obtain the preset control parameters. Based on the preset control parameters, the ultrasound excitation circuit is controlled to emit ultrasound pulse energy. The therapeutic ultrasound transducer receives the pulse energy emitted by the ultrasound excitation circuit and generates ultrasound waves to treat the patient's thrombosis, such as dissolving DVT, PE, PTS and other thrombi.

[0028] For example, the ultrasonic transducer includes any one of a piezoelectric ceramic transducer, a CMUT transducer, and a PMUT transducer.

[0029] S300: The temperature collection module collects temperature information of the ultrasonic transducer during the process of generating ultrasonic sound waves;

[0030] Further, the temperature collection module is connected to the control module through a CAN bus.

[0031] Specifically, it should be understood that when a catheter-mounted transducer is used for ultrasonic thrombolysis and ablation, the transducer inevitably generates heat due to the conversion of part of the energy into heat because of the electroacoustic conversion efficiency of the transducer. When the temperature of the transducer reaches a certain level, there is a risk of damaging blood, blood vessels or other normal tissues. The thermocouple is arranged in parallel with the ultrasonic transducer, and can convert heat into electricity. Therefore, the temperature change of the transducer is measured by measuring the thermoelectric potential generated by the thermocouple.

[0032] In this embodiment, the treatment catheter thermocouple is placed around the treatment ultrasonic transducer through a treatment catheter, and the temperature collection module collects temperature data of the treatment catheter thermocouple. The temperature collection module periodically collects temperature information during the process of generating ultrasonic sound waves by the ultrasonic transducer receiving pulse energy emitted by the ultrasonic excitation circuit according to a preset time period, and specifically monitors the temperature information of the thermocouple. The temperature information is the real-time temperature of the treatment area of the blood vessel transducer.

[0033] In this embodiment, the temperature collection module and the control module are preferably connected in communication through a CAN bus. The temperature collection module transmits the collected temperature information of the ultrasonic transducer to the control module through the CAN bus. The control module analyzes the temperature information and feeds back adjustment control parameters to adjust the ultrasonic pulse energy of the ultrasonic excitation circuit of the ultrasonic module, so as to indirectly adjust and control the temperature of the catheter-mounted transducer acting on the lesion nerve tissue of the human body.

[0034] S400: The control module receives the temperature information, judges whether the temperature information exceeds a preset threshold, if yes, controls the ultrasonic module to stop working, and if not, inputs the temperature information into a pre-constructed ultrasonic control information space to obtain adjustment control parameters.

[0035] Specifically, in this embodiment, the preset threshold is a critical temperature value of the temperature of the catheter heat exchanger that can cause damage to the normal nerve tissue around the lesion blood vessel of the patient, which is set by the user doctor based on the temperature rise of the ultrasonic transducer in the patient's body. The ultrasonic control information space is a data analysis processing model that can output adjustment control parameters for adjusting the size of the ultrasonic pulse energy emitted by the ultrasonic excitation circuit of the ultrasonic module according to the temperature information and the temperature change within a preset time period. The construction method of the ultrasonic control information space is not limited in this embodiment.

[0036] The control module receives the temperature information, and the control module compares the temperature information with the preset threshold value. If the temperature information is higher than the preset threshold value, the control module controls the ultrasonic module to stop working. If the temperature information is within the preset threshold value range, the control module inputs the temperature information into a pre-constructed ultrasonic control information space to obtain the adjustment control parameter.

[0037] S500: The ultrasonic module controls the ultrasonic excitation circuit to emit adjusted ultrasonic pulse energy according to the adjustment control parameter.

[0038] Specifically, in the embodiment, when the temperature information is within the preset threshold value range, the temperature information is input into a pre-constructed ultrasonic control information space to obtain the adjustment control parameter for adjusting the pulse energy emitted by the ultrasonic excitation circuit of the ultrasonic module.

[0039] The control module transmits the adjustment control parameter to the ultrasonic module through a CAN bus, and the ultrasonic module controls the ultrasonic excitation circuit to emit adjusted ultrasonic pulse energy according to the adjustment control parameter.

[0040] The method provided in the embodiment receives an instruction issued by a user through a control module, controls the ultrasonic excitation circuit to emit ultrasonic pulse energy according to a preset control parameter, and controls the ultrasonic transducer to generate ultrasonic sound waves under the ultrasonic pulse energy. A temperature acquisition module acquires temperature information of the ultrasonic transducer during the generation of the ultrasonic sound waves. The control module receives the temperature information and determines whether the temperature information exceeds a preset threshold value. If yes, the control module controls the ultrasonic module to stop working. If no, the control module inputs the temperature information into a pre-constructed ultrasonic control information space to obtain an adjustment control parameter. The ultrasonic module controls the ultrasonic excitation circuit to emit adjusted ultrasonic pulse energy according to the adjustment control parameter. The real-time temperature condition of the transducer during the catheter treatment is fed back in time, the pulse energy emitted by the ultrasonic excitation circuit is adaptively adjusted, the safety of the equipment is ensured, and efficient treatment is provided for the patient.

[0041] Further, as shown in Figure 2 The temperature acquisition module includes a connected thermocouple differential signal filtering module, a thermocouple digital conversion circuit, and a temperature acquisition control circuit. The temperature acquisition control circuit is used to control compensation correction conversion parameters in the thermocouple digital conversion circuit. The temperature acquisition module acquires temperature information of the ultrasonic transducer during the generation of the ultrasonic sound waves. The method provided in the present application further includes the following steps:

[0042] S310: The thermocouple differential signal filtering module receives the first signal of the thermocouple, performs differential analog processing to obtain a differential analog signal, and sends the differential analog signal to the thermocouple digital conversion circuit, wherein the thermocouple is arranged side by side with the ultrasonic transducer.

[0043] S320: The thermocouple digital conversion circuit receives the differential analog signal and performs conversion processing on the differential analog signal according to the compensation correction conversion parameter to obtain the temperature information and sends the temperature information to the temperature acquisition control circuit.

[0044] S330: The temperature acquisition control circuit receives the temperature information and sends the temperature information to the control module.

[0045] Specifically, in the embodiment, to avoid the attenuation of the treatment catheter thermocouple signal in the transmission process and the interference from the external environment, the treatment catheter thermocouple temperature acquisition circuit is designed as a temperature acquisition module generated by a module acquisition unit, which is separated from the control module and the ultrasonic module. The temperature acquisition module, the control module, and the ultrasonic module are preferably connected through a CAN bus. One end of the temperature acquisition module is connected to the control module through a two-meter-long CAN bus, and the other end of the temperature acquisition module is connected to the treatment catheter thermocouple of the ultrasonic module.

[0046] The temperature acquisition module is separated from the control module and acquires the treatment catheter thermocouple signal near the catheter interface, so that the accuracy and reliability of the temperature information data obtained by the temperature acquisition module are higher.

[0047] The temperature acquisition module includes a connected thermocouple differential signal filtering module, a thermocouple digital conversion circuit, and a temperature acquisition control circuit. The temperature acquisition control circuit is used to control the compensation correction conversion parameter in the thermocouple digital conversion circuit. The temperature acquisition module acquires the temperature information reflected by the electrical signal converted from heat energy to electrical energy of the thermocouple in the process of generating ultrasonic waves by the ultrasonic transducer according to a preset time period. The thermocouple differential signal filtering module is used to improve the precision of the electrical signal.

[0048] The thermocouple differential signal filtering module receives the first signal of the thermocouple, performs differential analog processing to obtain a differential analog signal, and sends the differential analog signal to the thermocouple digital conversion circuit. The thermocouple digital conversion circuit receives the differential analog signal and performs conversion processing on the differential analog signal according to the compensation correction conversion parameter to obtain the temperature information and sends the temperature information to the temperature acquisition control circuit. The temperature acquisition control circuit receives the temperature information and sends the temperature information to the control module.

[0049] The embodiment realizes the technical effect of reducing the interference of the attenuation of the external environment and the treatment catheter thermocouple signal in the transmission process on the ultrasonic transducer temperature change collection precision, and obtaining the ultrasonic transducer temperature information with high precision, by modularizing the temperature collection circuit and constructing the temperature collection module including the thermocouple differential signal filtering module, the thermocouple digital conversion circuit and the temperature collection control circuit, thereby providing effective data reference for subsequent ultrasonic transducer temperature control.

[0050] Further, as shown in Figure 3 The method provided by the application further includes the following steps S400:

[0051] S410: constructing an ultrasonic control information database;

[0052] S420: constructing the ultrasonic control information space according to the ultrasonic control database;

[0053] S430: calculating the temperature change rate information according to the temperature information and the preset time period;

[0054] S440: inputting the temperature information and the temperature change rate information as the current node state into the ultrasonic control information space to obtain the adjustment control parameter.

[0055] Further, the ultrasonic control information database is constructed, and the method provided by the application further includes the following steps S410:

[0056] S411: collecting a plurality of temperature information of the thermocouple according to the preset time period to obtain a plurality of sample temperature information;

[0057] S412: calculating a plurality of sample temperature change rate information according to the plurality of sample temperature information;

[0058] S413: setting a plurality of sample adjustment control parameters for adjusting the ultrasonic excitation circuit according to the plurality of sample temperature information and the plurality of sample temperature change rate information;

[0059] S414: constructing the ultrasonic control information database based on the plurality of sample temperature information, the plurality of sample temperature change rate information and the plurality of sample adjustment control parameters.

[0060] Specifically, in the embodiment, the ultrasonic control information space is a data analysis processing model that can output the adjustment control parameter for adjusting the ultrasonic pulse energy size of the ultrasonic excitation circuit of the ultrasonic module according to the temperature information and the temperature change in the preset time period, and the construction method of the ultrasonic control information space is not limited in the embodiment.

[0061] The preferred construction method of the ultrasonic control information space is that, in each time period, the temperature information of the thermocouple is collected once according to a preset time period, a plurality of sample temperature information is obtained based on a plurality of preset time periods with time before and after the connection relationship, the sample temperature change rate in a preset time period is calculated according to two adjacent sample temperature information, and a plurality of sample temperature change rates of a plurality of node states corresponding to a plurality of preset time periods are obtained by the same method. The preset time period is the time period of the temperature acquisition module collecting the temperature information of the ultrasonic transducer, which can be 5 seconds or 10 seconds, etc.

[0062] According to the plurality of preset time periods, the plurality of sample temperature information and the plurality of sample temperature change rate information, a plurality of sample adjustment control parameters for adjusting the ultrasonic excitation circuit are obtained, the plurality of sample adjustment control parameters have a one-to-one correspondence with the plurality of node states, and the ultrasonic control information database is constructed based on the correspondence between the plurality of sample temperature information, the plurality of sample temperature change rate information and the plurality of sample adjustment control parameters. The plurality of sample adjustment control parameters specifically include parameters for adjusting the transmission energy of the ultrasonic excitation circuit and the working frequency of the ultrasonic module. Under the adjustment of different sample adjustment control parameters, the temperature at which the ultrasonic transducer works will change, thereby controlling the temperature to avoid the situation of harming the patient and damaging the equipment.

[0063] According to the ultrasonic control database, the ultrasonic control information space is constructed, the temperature change rate information is calculated according to the temperature information of the catheter-mounted transducer of the ultrasonic module and the preset time period; the temperature information and the temperature change rate information are taken as the current time node and the working state of the ultrasonic module, and the adjustment control parameter is obtained by inputting the ultrasonic control information space, and the control module generates a control instruction based on the adjustment control parameter to adjust the working parameter of the ultrasonic excitation circuit of the ultrasonic module, and adjusts the pulse energy emitted by the ultrasonic excitation circuit.

[0064] The embodiment constructs the ultrasonic control information database with temperature information-change rate-adjustment control parameter mapping relationship by collecting sample temperature information and calculating the temperature change rate of the sample temperature information based on the preset time period, and constructs the ultrasonic control information space based on the ultrasonic control information database, so that the adjustment control parameter can be generated based on the real-time temperature information and the calculated temperature change rate to realize the self-adaptive adjustment of the ultrasonic sound power, and the technical effect of efficiently treating the patient's lesion in the safe state of the catheter-mounted ultrasonic medical equipment is achieved.

[0065] Further, according to the ultrasonic control database, the ultrasonic control information space is constructed, and the method provided in the present application further includes the following steps:

[0066] S421: According to the ultrasonic control database, a first temperature node state is obtained, wherein the first temperature node state includes first sample temperature information and first sample temperature change rate information;

[0067] S422: A sample adjustment control parameter adjusted according to the first temperature node state is obtained as a first adjustment behavior;

[0068] S423: The first temperature node state and the first adjustment behavior are input into the ultrasonic control information space to obtain a second temperature node state, wherein the second temperature node state includes second sample temperature information and second sample temperature change rate information;

[0069] S424: The N-1 adjustment behavior and the N node state are continuously obtained;

[0070] S425: A mapping relationship between the N node state and the N-1 adjustment behavior is constructed;

[0071] S426: According to the mapping relationship, the ultrasonic control information space is constructed.

[0072] Specifically, in the present embodiment, the construction method of the ultrasonic control information space is preferably based on Markov decision process, according to a plurality of preset time periods in which a plurality of sample temperature information is collected in the ultrasonic control database, a first preset time period and a second preset time period are obtained, a first temperature node state is obtained, the first temperature node state includes first sample temperature information and first sample temperature change rate information, a sample adjustment control parameter adjusted according to the first temperature node state is obtained as a first adjustment behavior, the first temperature node state and the first adjustment behavior are input into the ultrasonic control database, the first temperature node state is adjusted based on the first adjustment behavior, a second temperature node state is obtained in the next preset time period, the second temperature node state includes second sample temperature information and second sample temperature change rate information, the N-1 adjustment behavior and the N node state are continuously constructed, N is a positive integer, a mapping relationship between the N node state and the N-1 adjustment behavior is constructed, according to the mapping relationship, the ultrasonic control information space is constructed, and the ultrasonic control information space includes different node states and adjustment behaviors for adjusting the node states.

[0073] The embodiment obtains the adjustment behavior generation ultrasound control information space meeting the optimal effect of patient treatment by calculating the sample temperature change rate as the sample temperature node state and corresponding generation of the sample temperature node state adjustment, and provides the technical effect of accurate adjustment control parameters for the feedback adjustment control of the ultrasonic excitation circuit pulse energy emission value of the ultrasonic module based on the temperature information and the temperature change condition obtained in real time based on the preset time period.

[0074] Embodiment two

[0075] As Figure 4 shown, in order to more clearly explain the technical scheme of the trans-catheter ultrasound control method based on temperature monitoring, the embodiment of the application provides a trans-catheter ultrasound control system based on temperature monitoring, which is specifically as follows.

[0076] The trans-catheter ultrasound control system based on temperature monitoring comprises a control module, an ultrasound module and a temperature acquisition module. The control module is used for user input control parameter to start the operation of the ultrasound module, and to adjust the operation state of the ultrasound module based on the obtained temperature information of the ultrasound module.

[0077] In the actual application of the trans-catheter ultrasound control system based on temperature monitoring, the user inputs the preset control parameter for controlling the ultrasound module to emit ultrasonic pulse energy based on the touch screen or the key of the control module, and generates an instruction. The control module and the ultrasound module are connected based on CAN bus, and the instruction is sent to the ultrasound module via CAN bus. The ultrasound module comprises an ultrasonic excitation circuit and an ultrasonic transducer. The control module receives the user instruction sent by the control module, controls the ultrasonic excitation circuit to emit ultrasonic pulse energy based on the control parameter of the instruction, and the ultrasonic transducer generates ultrasonic sound waves under the ultrasonic pulse energy. The electroacoustic conversion efficiency of the ultrasonic transducer causes part of the electric energy to be converted into heat energy, and the ultrasonic transducer itself is heated. The temperature change of the ultrasonic transducer is obtained by acquiring the thermocouple temperature placed around the ultrasonic transducer. The temperature acquisition module and the control module are connected to the ultrasound module through CAN bus, and are used for acquiring the temperature information of the thermocouple of the ultrasonic transducer, and transmitting the temperature information to the control module through CAN bus. The control module receives the temperature information, and judges whether the temperature information exceeds the preset threshold value. If yes, the ultrasound module is controlled to stop working, and if not, the temperature information is input into the pre-constructed ultrasound control information space to obtain the adjustment control parameter, and the ultrasonic excitation circuit of the ultrasound module is controlled to emit the adjusted ultrasonic pulse energy according to the adjustment control parameter.

[0078] The temperature acquisition module comprises a thermocouple differential signal filtering module, a thermocouple digital conversion circuit and a temperature acquisition control circuit, the thermocouple differential signal filtering module is used for acquiring a first signal of a thermocouple, the thermocouple is arranged beside an ultrasonic transducer and is used for detecting temperature information when the ultrasonic transducer generates ultrasonic sound waves, the thermocouple differential signal filtering module carries out differential analog processing on the first signal to obtain a differential analog signal and sends the differential analog signal to the thermocouple digital conversion circuit, the thermocouple digital conversion circuit receives and converts the differential analog signal to obtain the temperature information and sends the temperature information to the temperature acquisition control circuit, and the temperature acquisition control circuit receives the temperature information and sends the temperature information to the control module.

[0079] The technical scheme provided in the application has at least the following technical effects or advantages:

[0080] The application provides a trans-catheter ultrasonic control system based on temperature monitoring, which is applied to a trans-catheter ultrasonic control method based on temperature monitoring. The system comprises an ultrasonic module, a temperature acquisition module and a control module. The ultrasonic module comprises an ultrasonic excitation circuit and an ultrasonic transducer. The ultrasonic module works under the instruction of a user to emit ultrasonic pulse energy. The ultrasonic transducer generates ultrasonic sound waves under the ultrasonic pulse energy. The temperature acquisition module is connected to the ultrasonic module through a CAN bus with the control module. The temperature acquisition module is used for acquiring temperature information of the ultrasonic transducer. The control module is used for receiving the temperature information and judging whether the temperature information exceeds a preset threshold. If yes, the control module controls the ultrasonic module to stop working. If no, the control module inputs the temperature information into a pre-constructed ultrasonic control information space to obtain an adjustment control parameter. The control module controls the ultrasonic module to control the ultrasonic excitation circuit to emit an adjusted ultrasonic pulse energy according to the adjustment control parameter. The temperature acquisition module comprises a thermocouple differential signal filtering module, a thermocouple digital conversion circuit and a temperature acquisition control circuit. The thermocouple differential signal filtering module is used for acquiring a first signal of a thermocouple. After differential analog processing, the thermocouple differential signal filtering module obtains a differential analog signal and sends the differential analog signal to the thermocouple digital conversion circuit. The thermocouple is arranged beside the ultrasonic transducer. The thermocouple digital conversion circuit receives and converts the differential analog signal to obtain the temperature information and sends the temperature information to the temperature acquisition control circuit. The temperature acquisition control circuit receives the temperature information and sends the temperature information to the control module. The application achieves the technical effect that the real-time temperature condition of a trans-catheter treatment transducer is fed back in time, the pulse energy emitted by the ultrasonic excitation circuit is adaptively adjusted, and efficient treatment is provided for a patient in a safe state of the equipment.

[0081] Embodiment three

[0082] Based on the same inventive concept as the temperature monitoring based transcatheter ultrasound control method in the foregoing embodiment, the present application provides a temperature monitoring based transcatheter ultrasound control system, wherein the system comprises: Figure 5 As shown in the foregoing embodiment, the present application provides a temperature monitoring based transcatheter ultrasound control system, wherein the system comprises:

[0083] An instruction receiving processing module 11 is configured to control the module to receive an instruction issued by a user and control the ultrasound excitation circuit to emit ultrasound pulse energy according to preset control parameters;

[0084] An ultrasound sound wave generating module 12 is configured to cause the ultrasound transducer to generate ultrasound sound waves under the ultrasound pulse energy;

[0085] A temperature information collecting module 13 is configured to cause the temperature collecting module to collect temperature information of the ultrasound transducer during the generation of the ultrasound sound waves, and the temperature collecting module is connected to the control module through a CAN bus;

[0086] A temperature information judging module 14 is configured to cause the control module to receive the temperature information, judge whether the temperature information exceeds a preset threshold, if yes, control the ultrasound module to stop working, and if not, input the temperature information into a pre-constructed ultrasound control information space to obtain an adjustment control parameter;

[0087] A control parameter adjusting module 15 is configured to cause the ultrasound module to control the ultrasound excitation circuit to emit an adjusted ultrasound pulse energy according to the adjustment control parameter.

[0088] Further, the temperature information collecting module 13 further comprises:

[0089] A differential analog processing unit is configured to cause the thermocouple differential signal filtering module to receive a first signal of a thermocouple, perform differential analog processing to obtain a differential analog signal, and send the differential analog signal to the thermocouple digital conversion circuit, and the thermocouple is arranged side by side with the ultrasound transducer;

[0090] A temperature information obtaining unit is configured to cause the thermocouple digital conversion circuit to receive the differential analog signal and perform conversion processing on the differential analog signal according to the compensation correction conversion parameter to obtain the temperature information and send the temperature information to the temperature collecting control circuit;

[0091] An information receiving and forwarding unit is configured to cause the temperature collecting control circuit to receive the temperature information and send the temperature information to the control module.

[0092] Further, the temperature information judging module 14 further comprises:

[0093] A database constructing unit is configured to construct an ultrasound control information database;

[0094] An information space constructing unit is configured to construct the ultrasound control information space according to the ultrasound control database.

[0095] a temperature change rate calculation unit configured to calculate temperature change rate information according to the temperature information and a preset time period;

[0096] a control parameter obtaining unit configured to input the temperature information and the temperature change rate information as a current node state into the ultrasonic control information space to obtain the adjustment control parameter.

[0097] Further, the database construction unit further comprises:

[0098] a sample data obtaining unit configured to collect a plurality of temperature information of a thermocouple according to the preset time period to obtain a plurality of sample temperature information;

[0099] a data change rate obtaining unit configured to calculate a plurality of sample temperature change rate information according to the plurality of sample temperature information;

[0100] a sample parameter obtaining unit configured to set a plurality of sample adjustment control parameters for adjusting the ultrasonic excitation circuit according to the plurality of sample temperature information and the plurality of sample temperature change rate information;

[0101] a database generating unit configured to construct the ultrasonic control information database based on the plurality of sample temperature information, the plurality of sample temperature change rate information and the plurality of sample adjustment control parameters.

[0102] Further, the ultrasonic control information space is constructed according to the ultrasonic control database, and the method provided in the present application further comprises the following steps S420:

[0103] S421: obtaining a first temperature node state according to the ultrasonic control database, wherein the first temperature node state comprises first sample temperature information and first sample temperature change rate information;

[0104] S422: obtaining a sample adjustment control parameter adjusted according to the first temperature node state as a first adjustment behavior;

[0105] S423: inputting the first temperature node state and the first adjustment behavior into the ultrasonic control information space to obtain a second temperature node state, wherein the second temperature node state comprises second sample temperature information and second sample temperature change rate information;

[0106] S424: continuing to obtain an N-1 adjustment behavior and an N node state;

[0107] S425: constructing a mapping relationship between the N node state and the N-1 adjustment behavior;

[0108] S426: According to the mapping relationship, the ultrasound control information space is constructed.

[0109] Any one of the above methods or steps can be stored as computer instructions or programs in various types of computer memories, and the computer instructions or programs are recognized by various types of computer processors, thereby realizing any one of the above methods or steps.

[0110] Embodiment Four

[0111] Based on the same inventive concept as the temperature monitoring based transcatheter ultrasound control system in Embodiment Two, this embodiment also provides a transcatheter ultrasound treatment system, which includes the temperature monitoring based transcatheter ultrasound control system in Embodiment Two.

[0112] Based on the above specific embodiments of the present application, any improvement and modification of the present application made by those skilled in the art without departing from the principles of the present application shall fall within the scope of the patent protection of the present application.

Claims

1. A transcatheter ultrasound control system based on temperature monitoring, characterized in that, The system includes: An ultrasonic module, comprising an ultrasonic excitation circuit and an ultrasonic transducer, wherein the ultrasonic module operates under user command to emit ultrasonic pulse energy, and the ultrasonic transducer generates ultrasonic sound waves under the ultrasonic pulse energy; A temperature acquisition module is provided, which is connected to the ultrasonic module via a CAN bus. The temperature acquisition module is used to acquire the temperature information of the ultrasonic transducer. A control module is configured to receive the temperature information and determine whether the temperature exceeds a preset threshold. If so, the control module stops working; otherwise, the control module inputs the temperature information into a pre-constructed ultrasonic control information space to obtain adjustment control parameters. The control module then controls the ultrasonic excitation circuit to emit adjustment ultrasonic pulse energy according to the adjustment control parameters. Inputting the temperature information into the pre-constructed ultrasonic control information space includes: constructing an ultrasonic control information database; constructing the ultrasonic control information space based on the ultrasonic control information database; calculating the temperature change rate information based on the temperature information and a preset time period; and inputting the temperature information and the temperature change rate information as the current node state into the ultrasonic control information space to obtain the adjustment control parameters. The temperature acquisition module includes a thermocouple differential signal filtering module, a thermocouple digital conversion circuit, and a temperature acquisition control circuit. The thermocouple differential signal filtering module is used to acquire the first signal of the thermocouple, perform differential analog processing to obtain a differential analog signal, and send it to the thermocouple digital conversion circuit. The thermocouple digital conversion circuit receives the differential analog signal and performs conversion processing to obtain the temperature information, which is then sent to the temperature acquisition control circuit. The temperature acquisition control circuit receives the temperature information and sends it to the control module. The thermocouple and the ultrasonic transducer are arranged side by side. The temperature acquisition module is connected to the control module via a CAN bus; The ultrasonic transducer includes any one of piezoelectric ceramic transducers, CMUT transducers, and PMUT transducers.

2. A transcatheter ultrasound control system based on temperature monitoring, characterized in that, The system includes: The instruction receiving and processing module is used to control the ultrasonic excitation circuit to emit ultrasonic pulse energy according to the preset control parameters. An ultrasonic wave generating module is used by an ultrasonic transducer to generate ultrasonic waves under the ultrasonic pulse energy. A temperature information acquisition module is used to acquire temperature information of the ultrasonic transducer during the process of generating ultrasonic waves. The temperature information judgment module is used to control the module to receive the temperature information, determine whether the temperature information exceeds a preset threshold, and if so, control the ultrasound module to stop working; if not, input the temperature information into a pre-constructed ultrasound control information space to obtain adjustment control parameters. A control parameter adjustment module is used to control the ultrasonic excitation circuit to emit adjusted ultrasonic pulse energy according to the adjustment control parameters. The temperature information determination module also includes: Database construction unit, used to build an ultrasonic control information database; An information space construction unit is used to construct the ultrasonic control information space based on the ultrasonic control information database. The temperature change rate calculation unit is used to calculate the temperature change rate information based on the temperature information and a preset time period. The control parameter acquisition unit is used to input the temperature information and the temperature change rate information as the current node state into the ultrasonic control information space to obtain the adjustment control parameters.

3. A transcatheter ultrasound therapy system, characterized in that, Includes the transcatheter ultrasound control system based on temperature monitoring as described in claim 2.

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