A mesh phototherapy device and its preparation method

Abstract

This invention discloses a mesh-like phototherapy device and its fabrication method. The mesh-like phototherapy device includes: a substrate layer comprising multiple substrate strips extending along a first direction; the multiple substrate strips are arranged sequentially at intervals along a second direction; the first direction and the second direction intersect each other; a sensor layer located on one side of the substrate layer; the sensor layer comprising multiple strip-shaped sensors extending along the second direction; the multiple strip-shaped sensors are arranged sequentially at intervals along the first direction; wherein, the substrate layer and the sensor layer constitute a mesh structure; a phototherapy luminescent layer located on the side of the sensor layer away from the substrate layer; and a protective layer located at least on the side of the phototherapy luminescent layer away from the substrate; the protective layer is used to protect the phototherapy luminescent layer. The mesh structure formed by the substrate layer and the sensor layer improves the air permeability of the phototherapy device while maintaining good bending performance, thus ensuring the therapeutic effect of the device.

Description

Technical Field

[0001] This invention relates to the field of phototherapy technology, and more particularly to a mesh phototherapy device and its preparation method. Background Technology

[0002] OLED (Organic Light-Emitting Diode) has attracted much attention due to its characteristics such as good light emission uniformity, thinness, flexibility, and stretchability, and its application in phototherapy has become increasingly widespread in recent years.

[0003] However, due to the need for status monitoring in current OLED phototherapy devices, sensor and other film structures have been added. But adding these film structures to the OLED screen results in poor screen permeability, which in turn reduces the overall permeability of the phototherapy device. When placed on the lesion, this makes it difficult for the skin to breathe, leading to bacterial growth and even local inflammation over time. This hinders the further development of OLED phototherapy devices. Summary of the Invention

[0004] This invention provides a mesh phototherapy device and its preparation method to improve the device's air permeability and flexibility, thereby ensuring the device's therapeutic effect.

[0005] According to one aspect of the present invention, a mesh phototherapy device is provided, comprising:

[0006] The substrate layer includes a plurality of substrate strips extending along a first direction; the plurality of substrate strips are arranged at intervals along a second direction; the first direction and the second direction intersect each other;

[0007] A sensor layer is located on one side of the substrate layer; the sensor layer includes a plurality of strip sensors extending along the second direction; the plurality of strip sensors are arranged at intervals along the first direction; wherein, the substrate layer and the sensor layer form a mesh structure;

[0008] A phototherapy luminescent layer is located on the side of the sensor layer away from the substrate layer; wherein the light-emitting surface of the phototherapy luminescent layer is the surface away from the substrate layer; the phototherapy luminescent layer is electrically insulated from the sensor layer.

[0009] A protective layer; the protective layer is located at least on the side of the phototherapy luminescent layer away from the substrate layer; the protective layer is used to protect the phototherapy luminescent layer.

[0010] Optionally, the phototherapy luminescent layer is a single, continuous film layer;

[0011] The mesh phototherapy device further includes a planarization layer located on the side of the sensor layer away from the substrate layer; the planarization layer is used to form a flat surface.

[0012] Optionally, the phototherapy light-emitting layer includes a plurality of light-emitting strips extending along the first direction; the plurality of light-emitting strips are arranged sequentially at intervals along the second direction; each light-emitting strip corresponds to a substrate strip, and the vertical projection of the light-emitting strip on the substrate layer and its corresponding substrate strip at least partially overlap;

[0013] Alternatively, the phototherapy luminescent layer includes a plurality of luminescent strips extending along the second direction; the plurality of luminescent strips are arranged sequentially at intervals along the first direction; each luminescent strip corresponds to a strip-shaped sensor, and the vertical projection of the luminescent strip on the substrate layer and the vertical projection of the corresponding strip-shaped sensor on the substrate layer at least partially overlap.

[0014] Optionally, the strip sensor may include a temperature sensor or a pressure sensor;

[0015] Alternatively, the strip sensor may include a temperature sensor and a pressure sensor, and there may be multiple temperature sensors and multiple pressure sensors; the temperature sensors and the pressure sensors may be arranged alternately in sequence.

[0016] Optionally, a water-oxygen barrier layer is further included between the phototherapy luminescent layer and the protective layer, the water-oxygen barrier layer being used to prevent water and oxygen from damaging the organic luminescent material;

[0017] The material of the water and oxygen barrier layer includes at least one of aluminum oxide, silicon oxide, titanium oxide, and zirconium oxide.

[0018] Optionally, the material of the substrate layer includes at least one selected from polyethylene terephthalate, polymethyl methacrylate, cellulose, fibroin, acrylic acid, and polydimethylsiloxane.

[0019] The pressure sensor is made of carbon nanotubes and polylactic acid; the temperature sensor is made of 1-butyl-3-methylimidazolium chloride and acrylic acid.

[0020] The material of the planarization layer includes pyrene;

[0021] The material of the protective layer includes perylene.

[0022] Optionally, the width of the substrate strip ranges from 1 mm to 1 cm; the width of the interval between two adjacent substrate strips ranges from 1 mm to 1 cm.

[0023] The width of the strip sensor ranges from 1 mm to 1 cm; the width of the gap between two adjacent strip sensors ranges from 1 mm to 1 cm.

[0024] The pore area of ​​the mesh structure ranges from 1 mm. 2 ~1cm 2 .

[0025] Optionally, each of the light-emitting strips includes:

[0026] Substrate;

[0027] A first electrode layer is located on the side of the substrate away from the substrate layer; the first electrode layer includes a plurality of first electrodes, which are arranged at intervals along the direction in which the light-emitting strip extends.

[0028] An organic light-emitting material layer is located on the side of the first electrode layer away from the substrate;

[0029] The second electrode layer is located on the side of the organic light-emitting material layer away from the substrate; the second electrode layer includes a plurality of second electrodes, which are disposed in a one-to-one correspondence with the first electrodes;

[0030] An encapsulation layer is located on the side of the second electrode layer away from the substrate.

[0031] Optionally, in the extension direction of the light-emitting strip, the first electrodes located in the same light-emitting strip are connected in series or in parallel; after the first electrodes in each light-emitting strip are connected in series or in parallel, they are connected to a corresponding first external electrode; different first external electrodes are connected to different first power output terminals.

[0032] In the arrangement direction of the plurality of light-emitting strips, the second electrodes of two adjacent light-emitting strips are electrically connected; the second electrodes of all the light-emitting strips are connected in series or in parallel in the arrangement direction of the light-emitting strips and then connected to a corresponding second external electrode; different second external electrodes are connected to different second power output terminals.

[0033] According to another aspect of the present invention, a method for preparing a mesh phototherapy device is provided, for forming the mesh phototherapy device according to any embodiment of the present invention, comprising:

[0034] A 3D printed substrate layer; the substrate layer includes a plurality of substrate strips extending along a first direction; the plurality of substrate strips are arranged sequentially at intervals along a second direction; the first direction and the second direction intersect each other;

[0035] A sensor layer is 3D printed on one side of the substrate layer; the sensor layer includes a plurality of strip sensors extending along the second direction; the plurality of strip sensors are arranged at intervals along the first direction; wherein, the substrate layer and the sensor layer form a mesh structure;

[0036] A phototherapy luminescent layer is 3D printed on the side of the sensor layer away from the substrate layer; wherein the light-emitting surface of the phototherapy luminescent layer is the surface away from the substrate layer;

[0037] A protective layer is formed; the protective layer is located at least on the side of the phototherapy luminescent layer away from the substrate layer; the protective layer is used to protect the phototherapy luminescent layer.

[0038] The technical solution provided by this invention involves configuring a substrate layer as multiple substrate strips extending along a first direction, with these strips arranged at intervals along a second direction; the first and second directions intersect each other; and configuring a sensor layer located on one side of the substrate layer as including multiple strip-shaped sensors extending along the second direction, with these strip-shaped sensors arranged at intervals along the first direction. This allows the substrate layer and sensor layer to form a mesh structure, improving the breathability of the phototherapy device while maintaining good bending performance, thus ensuring the therapeutic effect of the device. Furthermore, the phototherapy luminescent layer can also be configured as a strip structure, which can further improve the breathability of the phototherapy device.

[0039] It should be understood that the description in this section is not intended to identify key or essential features of the embodiments of the present invention, nor is it intended to limit the scope of the invention. Other features of the invention will become readily apparent from the following description. Attached Figure Description

[0040] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0041] Figure 1 This is a schematic diagram of the structure of a mesh phototherapy device provided in an embodiment of the present invention;

[0042] Figure 2 yes Figure 1 Cross-sectional view of the structure shown along line AA1;

[0043] Figure 3 This is a schematic diagram of another mesh phototherapy device provided in an embodiment of the present invention;

[0044] Figure 4This is a schematic diagram of another mesh phototherapy device provided in an embodiment of the present invention;

[0045] Figure 5 yes Figure 4 Cross-sectional view of the structure shown along line AA1;

[0046] Figure 6 This is an exploded view of a phototherapy luminescent layer provided in an embodiment of the present invention;

[0047] Figure 7 This is a flowchart illustrating a method for preparing a mesh phototherapy device according to an embodiment of the present invention;

[0048] Figure 8 This is a schematic diagram of a structure prepared by extrusion printing according to an embodiment of the present invention;

[0049] Figure 9 This is a schematic diagram of a structure prepared by inkjet printing according to an embodiment of the present invention. Detailed Implementation

[0050] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of the present invention.

[0051] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this invention are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of the invention described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0052] This invention provides a mesh phototherapy device. Figure 1 This is a schematic diagram of the structure of a mesh phototherapy device provided in an embodiment of the present invention. It should be noted that... Figure 1 The positional relationship between the substrate layer 10, the sensor layer 20, and the phototherapy luminescent layer 40 is only shown as an example. Figure 2 yes Figure 1The cross-sectional view of the structure shown along line AA1 is for reference. Figure 1 and Figure 2 The mesh phototherapy device includes:

[0053] The substrate layer 10 includes a plurality of substrate strips 11 extending along a first direction X; the plurality of substrate strips 11 are arranged sequentially at intervals along a second direction Y; the first direction X and the second direction Y intersect each other;

[0054] The sensor layer 20 is located on one side of the substrate layer 10; the sensor layer 20 includes a plurality of strip sensors 21 extending along the second direction Y; the plurality of strip sensors 21 are arranged sequentially at intervals along the first direction X; wherein, the substrate layer 10 and the sensor layer 20 form a mesh structure; the strip sensors 21 include at least one of temperature sensor 212 and pressure sensor 211.

[0055] The phototherapy light-emitting layer 40 is located on the side of the sensor layer 20 away from the substrate layer 10; wherein, the light-emitting surface of the phototherapy light-emitting layer 40 is the surface away from the substrate layer 10; the phototherapy light-emitting layer 40 is electrically insulated from the sensor layer 20.

[0056] Protective layer 50; the protective layer 50 is located at least on the side of the phototherapy luminescent layer 40 away from the substrate 8; the protective layer 50 is used to protect the phototherapy luminescent layer 40.

[0057] Specifically, the substrate layer 10 includes a plurality of substrate strips 11 extending along a first direction X, and the plurality of substrate strips 11 are arranged sequentially at intervals along a second direction Y; it can be understood that the substrate layer 10 is changed from a solid film layer in the prior art to a strip structure arranged at intervals, and the distance between two adjacent substrate strips 11 is greater than zero. The material of the substrate layer 10 may include polyethylene terephthalate (PET), polymethyl methacrylate (PM), cellulose, fibroin, acrylic acid, or polydimethylsiloxane (PMDS), and the substrate layer 10 is used as a support structure for the phototherapy device. A sensor layer 20 is disposed on one side surface of the substrate layer 10, and the sensor layer 20 includes a plurality of strip sensors 21 extending along the second direction Y, and the plurality of strip sensors 21 are arranged sequentially at intervals along the first direction X; it can be understood that the sensor layer 20 is changed from a solid film layer in the prior art to a strip structure arranged at intervals, and the distance between two adjacent strip sensors 21 is greater than zero.

[0058] Since the substrate strip 11 extends along the first direction X, and the strip sensor 21 extends along the second direction Y, and the first direction X and the second direction Y intersect each other, the substrate strip 11 and the strip sensor 21 intersect each other. Multiple substrate strips 11 are arranged alternately along the second direction Y, and multiple strip sensors 21 are arranged alternately along the first direction X, so that the substrate layer 10 and the sensor layer 20 form a porous mesh structure. When the first direction X and the second direction Y are not perpendicular to each other, the pore shape of the mesh structure is a parallelogram; when the first direction X and the second direction Y are perpendicular to each other, the pore shape of the mesh structure is rectangular. By forming a mesh structure between the substrate layer 10 and the sensor layer 20, the substrate layer 10, composed of substrate strips 11, provides support, and because the total thickness of the membrane layer at the pore locations of the phototherapy device is reduced, the difficulty of skin ventilation is also reduced; furthermore, the mesh structure can release the stress generated when the phototherapy device is bent, improving the flexibility of the phototherapy device.

[0059] The strip sensor 21 includes at least one of a temperature sensor 212 and a pressure sensor 211. It can be entirely configured as a temperature sensor 212; or entirely as a pressure sensor 211; or some strip sensors 21 can be configured as temperature sensors 212 and some as pressure sensors 211. If some strip sensors 21 are configured as temperature sensors 212 and some as pressure sensors 211, all temperature sensors 212 can be concentrated in one area, and all temperature sensors 212 can be concentrated in another area; or, temperature sensors 212 and pressure sensors 211 can be arranged alternately. The alternating arrangement of temperature sensors 212 and pressure sensors 211 can be understood as, along the first direction X, temperature sensors 212 and pressure sensors 211 are arranged adjacent to each other. This alternating arrangement improves the uniformity of pressure detection and temperature detection throughout the phototherapy device. The strip sensor 21 can be fabricated using Digital Light Processing (DLP) 3D printing. The pressure sensor 211 can be made of a conductive polymer composite of multi-walled carbon nanotubes (MWCNTs) and polylactic acid (PLA), while the temperature sensor 212 is made of a mixture of 1-butyl-3-methylimidazolium chloride and acrylic acid. The pressure sensor 211 works by deforming its thin sheet under external force (pressure), generating a piezoresistive impedance effect. This impedance change is converted into an electrical signal, and the applied pressure can be determined by detecting the electrical signal. Similarly, the temperature sensor 212 converts temperature changes into electrical signal changes, and temperature is detected by detecting these electrical signals.

[0060] The phototherapy luminescent layer 40 can be a single, continuous film or a strip-shaped structure. Figure 1 The phototherapy luminescent layer 40, as exemplarily shown, can be a single, continuous film. The phototherapy luminescent layer 40 consists of multiple luminescent structures and provides a light source for treatment. The phototherapy luminescent layer 40 is electrically insulated from the sensor layer 20, which can be achieved by using an insulating material as the substrate in the phototherapy luminescent layer 40. A layer of phenelzine (Pyrelin) is then deposited on the phototherapy luminescent layer 40 via CVD or MLD as a protective layer 50 to protect the entire device. The thickness of the Pyrelin deposition can be set from 1 μm to 20 μm, ensuring effective protection of the entire device while preventing interference with the bending and breathability of the phototherapy device. Furthermore, Pyrelin has good biocompatibility and will not cause damage to the skin upon contact.

[0061] Optionally, if the phototherapy luminescent layer 4 is a single film layer, a planarization layer 30 can be prepared on the side of the sensor layer 20 away from the substrate layer 10 before preparing the phototherapy luminescent layer 40. The planarization layer provides a flat surface for the preparation of the phototherapy luminescent layer 40. After the sensor layer 20 is printed, a layer of poly-para-xylylene can be deposited as the planarization layer 30 using chemical vapor deposition (CVD) or molecular layer deposition (MLD) equipment. Poly-para-xylylene is a high molecular weight polymer with many excellent functional characteristics. For example, it allows for precise control of the thickness and uniformity of the deposited film, acid and alkali resistance, good dielectric properties, colorless and high transparency, and is widely used in electrical insulation, moisture protection for sensors or medical instruments, and corrosion protection for metal coatings. Therefore, the planarization layer 30 can also protect the sensor and isolate it from the phototherapy luminescent layer 40, further preventing mutual interference between the two during operation. If the deposited phenelzine is too thin, it affects the protective effect on the sensor layer 20 and fails to meet the requirement of providing a smooth formation surface for the phototherapy luminescent layer 40. If the deposited phenelzine is too thick, it affects the bending performance and breathability of the device. In this embodiment of the invention, the thickness of the deposited phenelzine is set to 1μm to 20μm, which ensures the protection of the sensor layer 20, meets the requirement of providing a smooth formation surface for the phototherapy luminescent layer 40, and also prevents it from affecting the bending performance and breathability of the device. Since the planarization layer 30 is formed by CVD or MLD deposition of phenelzine, the molecules of the phenelzine material can adhere to various surfaces of the sensor through the pores.

[0062] The mesh phototherapy device provided in this embodiment of the invention comprises a substrate layer consisting of multiple substrate strips extending along a first direction, and the multiple substrate strips are arranged sequentially at intervals along a second direction; the first direction and the second direction intersect each other; the sensor layer located on one side of the substrate layer is configured to include multiple strip-shaped sensors extending along the second direction, and the multiple strip-shaped sensors are arranged sequentially at intervals along the first direction; so that the substrate layer and the sensor layer can form a mesh structure, which improves the air permeability of the phototherapy device while having good bending performance, thus ensuring the therapeutic effect of the device.

[0063] In one embodiment of the present invention, reference is made to... Figure 3 The phototherapy light-emitting layer 40 includes a plurality of light-emitting strips 41 extending along a first direction X; the plurality of light-emitting strips 41 are arranged sequentially at intervals along a second direction Y; each light-emitting strip 41 corresponds to a substrate strip 11, and the vertical projection of the light-emitting strip 41 on the substrate layer 10 and its corresponding substrate strip 11 at least partially overlap.

[0064] Or, refer to Figure 4The phototherapy light-emitting layer 40 includes a plurality of light-emitting strips 41 extending along the second direction Y; the plurality of light-emitting strips 41 are arranged sequentially at intervals along the first direction X; each light-emitting strip 41 corresponds to a strip sensor 21, and the vertical projection of the light-emitting strip 41 on the substrate layer 10 and the vertical projection of the corresponding strip sensor 21 on the substrate layer 10 at least partially overlap.

[0065] This can be understood as follows: setting the phototherapy light-emitting layer 40 into a strip structure can further improve the breathability and flexibility of the phototherapy device. Each light-emitting strip 41 can include multiple OLED light-emitting structures, that is, the light-emitting material in the light-emitting strip 41 is an organic light-emitting material. Figure 5 yes Figure 4 The cross-sectional view of the structure shown along line AA1 is for reference. Figure 4 and Figure 5 When the phototherapy luminescent layer 40 includes multiple luminescent strips 41, since the protective layer 50 is formed by CVD or MLD deposition of phenelzine, the molecules of the phenelzine material can adhere to the entire peripheral surface of the device through the pores.

[0066] Furthermore, since organic light-emitting materials are easily corroded by water vapor and oxygen in the external environment, leading to light-emitting failure, a water-oxygen barrier layer (not shown) can be placed between the phototherapy light-emitting layer 40 and the protective layer 50 to prevent water and oxygen from damaging the organic light-emitting material. The water-oxygen barrier layer can be prepared on the surface of the phototherapy light-emitting layer 40 using an atomic layer deposition (ALD) device. The material of the water-oxygen barrier layer can be oxides such as alumina, silicon oxide, titanium oxide, and zirconium oxide. Its thickness can range from 10 nm to 100 nm to prevent the water-oxygen barrier layer from being too thin, affecting its water-oxygen blocking performance, and to prevent the water-oxygen barrier layer from being too thick, causing it to crack due to excessive stress.

[0067] In one embodiment of the present invention, the phototherapy luminescent layer 40 includes a plurality of luminescent strips, as shown in the reference. Figure 6 An exemplary drawing of the phototherapy luminescent layer 40 includes eight luminescent strips 41, each luminescent strip comprising:

[0068] Substrate 8;

[0069] The first electrode layer 1 is located on the side of the substrate 8 away from the substrate layer 10; the first electrode layer 1 includes a plurality of first electrodes 111, which are arranged sequentially at intervals along the direction of the light-emitting strip 41.

[0070] Organic light-emitting material layer 3 is located on the side of the first electrode layer 1 away from the substrate 8;

[0071] The second electrode layer 5 is located on the side of the organic light-emitting material layer 3 away from the substrate 8; the second electrode layer 5 includes a plurality of second electrodes 555, and the second electrodes 555 are arranged in a one-to-one correspondence with the first electrode 111.

[0072] Encapsulation layer 7 is located on the side of the second electrode layer 5 away from the substrate 8.

[0073] OLEDs can be understood as optoelectronic devices that emit light through carrier injection and recombination. Specifically, electrons are injected through a metal cathode, and holes are injected through a metal anode. Electrons and holes recombine in the light-emitting material layer 3 to form excitons, which then de-emit light. If the first electrode layer 1 is the anode layer, then the second electrode layer 5 is the cathode layer; conversely, if the first electrode layer 1 is the cathode layer, then the second electrode layer 5 is the anode layer. The first electrode layer 1 includes multiple first electrodes 111, which are arranged sequentially at intervals along the direction of the light-emitting strip 41. The second electrode layer 5 includes multiple second electrodes 555, which are arranged in a one-to-one correspondence with the first electrodes 111. Each first electrode 111 and its corresponding second electrode 555, along with the organic light-emitting material layer 3 between the first electrode 111 and the second electrode 555, constitutes a light-emitting structure.

[0074] Taking the first electrode layer 1 as the anode layer and the second electrode layer 5 as the cathode layer as an example, a hole transport layer 2 may be included between the anode and the organic light-emitting material layer 3, and an electron transport layer 4 may be included between the cathode and the organic light-emitting material layer 3. Electrons are injected through the metal cathode and transported to the organic light-emitting material layer 3 through the electron transport layer 4, while holes are injected through the metal anode and transported to the organic light-emitting material layer 3 through the hole transport layer 2.

[0075] In one embodiment of the present invention, reference is made to... Figure 6 , combined Figure 3 and Figure 4 In the extension direction of the light-emitting strip 41, the first electrodes 111 located in the same light-emitting strip 41 are connected in series. After the first electrodes 111 in each light-emitting strip 41 are connected in series, they are connected to a first external electrode 101. Different first external electrodes 101 are connected to different first power output terminals. In the arrangement direction of the multiple light-emitting strips 41, the second electrodes 555 in two adjacent light-emitting strips 41 are electrically connected. After the second electrodes 555 of all light-emitting strips 41 are connected in series in the arrangement direction of the light-emitting strips 41, they are connected to a second external electrode 102. Different second external electrodes 102 are connected to different second power output terminals.

[0076] This can be understood as follows: the first electrodes 111 located in the same light-emitting strip 41 are connected in series. Each first electrode 111 located at the beginning or end is connected to a first external electrode 101, which receives the voltage signal output from the first power supply output terminal and transmits it to each first electrode 111. Each first electrode 111 in each light-emitting strip 41, after being connected in series, is connected to a corresponding first external electrode 101. Different first external electrodes 101 are connected to different first power supply output terminals; different first power supply output terminals can output the same voltage signal or the same voltage signal. In the arrangement direction of the multiple light-emitting strips 41, the second electrodes 555 in every two adjacent light-emitting strips 41 are electrically connected. This ensures that the second electrodes 555 of all light-emitting strips 41 are connected in series in the arrangement direction of the light-emitting strips 41. Each second electrode 555 located at the beginning or end is connected to a corresponding second external electrode 102; different second external electrodes 102 are connected to different second power supply output terminals. Different second power supply output terminals can output the same voltage signal or the same voltage signal.

[0077] In other words, the direction of the series connection of the first electrode 111 and the direction of the series connection of the second electrode 555 intersect each other. Only the light-emitting unit that receives current signals from both the first electrode 111 and the second electrode 555 can be lit. Therefore, the electrode connection method in this embodiment allows each light-emitting unit to be controlled individually. The connecting wires between the first electrodes 111 can be arranged on the same layer as the first electrodes 111. The connecting wires between the second electrodes 555 can be arranged on a different layer than the second electrodes 555, for example... Figure 6 As shown, after the second electrode layer 5 is prepared, an Ag paste layer is printed to form multiple silver traces 6 extending along the first direction X. The multiple silver traces 6 are arranged along the second direction Y. Each silver trace 6 is used to connect in series with a row of second electrodes 555 arranged along the first direction. One end of the silver trace 6 is connected to the second external electrode 102, thereby inputting a voltage signal to the second electrode 555.

[0078] In another embodiment of the present invention, in the extension direction of the light-emitting strip 41, the first electrodes 111 located in the same light-emitting strip 41 are connected in series sequentially; after the first electrodes 111 in each light-emitting strip 41 are connected in series sequentially, a first external electrode is connected accordingly; in the extension direction of the light-emitting strip 41, the second electrodes 555 located in the same light-emitting strip 41 are connected in series sequentially; after the second electrodes 555 in each light-emitting strip 41 are connected in series sequentially, a second external electrode is connected accordingly.

[0079] This can be understood as the direction in which the first electrode 111 is connected in series being parallel to the direction in which the second electrode 555 is connected in series. Figure 6The silver trace 6 extends along the second direction, which can realize synchronous control of the light-emitting units in the same light-emitting strip 41. If all the first external electrodes are connected to the same first power output terminal and all the second external electrodes are connected to the same second power output terminal, then the simultaneous control of all light-emitting strips 41 can be realized, thereby simplifying the opening and closing of the light-emitting structure in the phototherapy device.

[0080] In other embodiments, the first electrodes 111 located in the same light-emitting strip 41 can also be connected in parallel, with the first electrodes 111 in a light-emitting strip 41 sequentially connected in parallel and then correspondingly connected to a first external electrode; the second electrodes 555 located in the same light-emitting strip 41 can also be connected in parallel, with the second electrodes 555 in each light-emitting strip 41 sequentially connected in parallel and then correspondingly connected to a second external electrode. Specific details will not be elaborated here. In other embodiments, in the arrangement direction of the plurality of light-emitting strips 41, the second electrodes in adjacent light-emitting strips 41 are electrically connected; the second electrodes of all the light-emitting strips are sequentially connected in parallel in the arrangement direction of the light-emitting strips and then correspondingly connected to a second external electrode; different second external electrodes are connected to different second power output terminals.

[0081] Figure 6 The illustration shows each light-emitting strip as comprising a column of light-emitting units. In some embodiments of the present invention, each light-emitting strip may include two columns, three columns, or other numbers of light-emitting units, which can be set according to actual needs.

[0082] In one embodiment of the present invention, reference is made to... Figure 1 The width of the substrate strip 11 ranges from 1 mm to 1 cm; the width of the interval between two adjacent substrate strips 11 ranges from 1 mm to 1 cm, so as to avoid the substrate strip 11 being too narrow or the interval between two adjacent substrate strips 11 being too large, which would affect the support of the substrate layer 10; and to avoid the substrate strip 11 being too wide or the interval between two adjacent substrate strips 11 being too small, which would affect the flexibility and breathability of the substrate layer 10.

[0083] The width of the strip sensor 21 ranges from 1 mm to 1 cm; the width of the interval between two adjacent strip sensors 21 ranges from 1 mm to 1 cm, so as to avoid the strip sensor 21 being too narrow or the interval between two adjacent strip sensors 21 being too large, which would affect the accuracy of the sensor in monitoring temperature and / or pressure; and to avoid the strip sensor 21 being too wide or the interval between two adjacent strip sensors 21 being too small, which would affect the flexibility and breathability of the sensor layer 20.

[0084] The pore area of ​​the mesh structure ranges from 1 mm. 2 ~1cm 2 The larger the pore size, the better the bending performance and air permeability.

[0085] This invention also provides a method for preparing a mesh phototherapy device, used to form the mesh phototherapy device described in any of the above embodiments. Figure 7 This is a flowchart illustrating a method for preparing a mesh phototherapy device according to an embodiment of the present invention. (Refer to...) Figure 7 The preparation method of the mesh phototherapy device includes:

[0086] S110, 3D printed substrate layer; the substrate layer includes multiple substrate strips extending along a first direction; the multiple substrate strips are arranged sequentially at intervals along a second direction; the first direction and the second direction intersect each other.

[0087] Specifically, a substrate layer is formed using 3D printing technology, which serves as the support structure for the phototherapy device. The substrate layer comprises multiple substrate strips extending along a first direction, and these strips are arranged at intervals along a second direction Y. This can be understood as transforming the substrate layer from a single, continuous film layer in the prior art into a spaced-out strip structure. The material of the substrate layer can include polyethylene terephthalate (PET), polymethyl methacrylate (PM), cellulose, fibroin, acrylic acid, or polydimethylsiloxane (PMDS), and can be formed using 3D printing technology.

[0088] S120. A sensor layer is 3D printed on one side of the substrate layer; the sensor layer includes a plurality of strip sensors extending along a second direction; the plurality of strip sensors are arranged sequentially at intervals along a first direction; wherein the substrate layer and the sensor layer form a mesh structure; the strip sensors include at least one of a temperature sensor and a pressure sensor.

[0089] Specifically, a sensor layer is formed on one side surface of a substrate layer using 3D printing technology. Since the substrate strips extend along a first direction, and the strip-shaped sensors extend along a second direction, and these two directions intersect, the substrate strips and strip-shaped sensors also intersect. Multiple substrate strips are arranged alternately along the second direction, and multiple strip-shaped sensors are arranged alternately along the first direction, forming a porous mesh structure between the substrate layer and the sensor layer. This mesh structure ensures the substrate layer, composed of substrate strips, provides support while reducing the overall thickness of the membrane at the porous locations, thus reducing the difficulty of skin ventilation. Furthermore, the mesh structure can release stress generated during bending of the photomedical device, improving its bending performance. The strip-shaped sensors can be fabricated using digital light processing (DLP) 3D printing. The pressure sensor can be made of a conductive polymer composite of carbon nanotubes and polylactic acid, while the temperature sensor is made of a mixture of 1-butyl-3-methylimidazolium chloride and acrylic acid.

[0090] S130. A phototherapy luminescent layer is 3D printed on the side of the sensor layer away from the substrate layer; wherein the light-emitting surface of the phototherapy luminescent layer is the surface away from the substrate layer.

[0091] Specifically, the phototherapy luminescent layer can be a single film layer or a strip structure. If it is a strip structure, the phototherapy luminescent layer includes multiple luminescent strips extending along a first direction; the multiple luminescent strips are arranged sequentially at intervals along a second direction; each luminescent strip corresponds to a substrate strip, and the vertical projection of the luminescent strip on the substrate layer and its corresponding substrate strip at least partially overlap; or, the phototherapy luminescent layer includes multiple luminescent strips extending along a second direction; the multiple luminescent strips are arranged sequentially at intervals along the first direction; each luminescent strip corresponds to a strip sensor, and the vertical projection of the luminescent strip on the substrate layer and its corresponding strip sensor on the substrate layer at least partially overlap.

[0092] The luminescent strips in the phototherapy luminescent layer can be prepared by printing. Figure 8 This is a schematic diagram of a structure for extrusion printing preparation provided in an embodiment of the present invention. The extrusion printing preparation is carried out by controlling the printing nozzle 200 to print using driving pressure. Figure 9 This is a schematic diagram of an inkjet printing process provided in an embodiment of the present invention. The inkjet printing process is performed by using a gas-controlled spray nozzle 100. (Reference) Figure 8 and Figure 9 , combined Figure 6The method for preparing the luminescent strip includes: preparing an organic layer as a substrate 8 by extrusion printing, the material of which is PDMS or silicone, etc., and the thickness range can be 5-50μm. The substrate 8 can be a solid film or a strip structure; printing a first electrode layer 1 on the substrate by extrusion printing equipment, the first electrode layer 1 can serve as an anode layer, the material of which is Ag nanowires or other metal nanowires; printing a hole transport layer 2 by extrusion printing equipment, the material of the hole transport layer 2 can be PEDOT:PSS, which is an aqueous solution of a polymer with high conductivity, and different aqueous solutions with different conductivity can be obtained according to different formulations; preparing an organic light-emitting material layer 3 on the hole transport layer 2 by inkjet printing, the organic light-emitting material can be a polymer... [2-[(3,7-dimethyloctyl)oxy]-5-methoxy-1,4-benzene]-1,2-vinyldiyl](MDMO-PPV); an electron transport layer 4 is printed on the organic light-emitting material layer 3 using an extrusion printing device. The material can be silicone plastic. A second electrode layer 5, which serves as the cathode layer, is printed on the electron transport layer 4 using an extrusion printing device. The material can be gallium indium eutectic (eGaIn). An Ag paste layer is printed using an extrusion printing device to form a silver trace 6, which leads out the cathode and connects it to an external power source. An organic layer is printed using an extrusion printing device as an encapsulation layer 7. The material can be PDMS or silicone, etc. The encapsulation layer 7 can be a whole film layer or a strip structure.

[0093] During the fabrication process, each light-emitting strip can be fabricated individually, meaning that one light-emitting strip is fabricated before another is fabricated. Alternatively, all light-emitting strips can be formed with the same film layer simultaneously, and then the next identical film layer can be formed for all light-emitting strips. For example, after forming the substrate for all light-emitting strips, the first electrode layer for all light-emitting strips can be formed, and so on, until all film layers are fabricated.

[0094] S140, Form a protective layer; the protective layer is located at least on the side of the phototherapy luminescent layer away from the substrate; the protective layer is used to protect the phototherapy luminescent layer.

[0095] Specifically, a layer of phenelzine is deposited on the phototherapy luminescent layer using CVD or MLD as a protective layer to protect the entire device. The thickness of the phenelzine deposition can be set from 1μm to 20μm, ensuring effective protection of the entire device while preventing any impact on the bending and breathability of the phototherapy device. Furthermore, phenelzine has good biocompatibility and will not cause damage to the skin it comes into contact with.

[0096] Note that the above description is merely a preferred embodiment of the present invention and the technical principles employed. Those skilled in the art will understand that the present invention is not limited to the specific embodiments described herein, and various obvious changes, readjustments, and substitutions can be made without departing from the scope of protection of the present invention. Therefore, although the present invention has been described in detail through the above embodiments, the present invention is not limited to the above embodiments, and may include many other equivalent embodiments without departing from the concept of the present invention, the scope of which is determined by the scope of the appended claims.

Claims

1. A mesh phototherapy device, characterized in that, include: The substrate layer includes a plurality of substrate strips extending along a first direction; the plurality of substrate strips are arranged at intervals along a second direction. The first direction and the second direction intersect each other; A sensor layer is located on one side of the substrate layer; the sensor layer includes a plurality of strip sensors extending along the second direction; the plurality of strip sensors are arranged at intervals along the first direction; wherein, the substrate layer and the sensor layer form a mesh structure; A phototherapy luminescent layer is located on the side of the sensor layer away from the substrate layer; wherein the light-emitting surface of the phototherapy luminescent layer is the surface away from the substrate layer; the phototherapy luminescent layer is electrically insulated from the sensor layer. A protective layer; the protective layer is located at least on the side of the phototherapy luminescent layer away from the substrate layer; the protective layer is used to protect the phototherapy luminescent layer; The phototherapy luminescent layer includes multiple luminescent strips, and the vertical projections of the luminescent strips on the substrate layer and the vertical projections of the strip-shaped sensor on the substrate layer at least partially overlap.

2. The mesh phototherapy device according to claim 1, characterized in that, The phototherapy luminescent layer is a single, continuous film layer; The mesh phototherapy device further includes a planarization layer located on the side of the sensor layer away from the substrate layer; the planarization layer is used to form a flat surface.

3. The mesh phototherapy device according to claim 1, characterized in that, The phototherapy light-emitting layer includes a plurality of light-emitting strips extending along the first direction; the plurality of light-emitting strips are arranged sequentially at intervals along the second direction; each light-emitting strip corresponds to a substrate strip, and the vertical projection of the light-emitting strip on the substrate layer and its corresponding substrate strip at least partially overlap; Alternatively, the phototherapy luminescent layer includes a plurality of luminescent strips extending along the second direction; the plurality of luminescent strips are arranged sequentially at intervals along the first direction; each luminescent strip corresponds to a strip-shaped sensor, and the vertical projection of the luminescent strip on the substrate layer and the vertical projection of the corresponding strip-shaped sensor on the substrate layer at least partially overlap.

4. The mesh phototherapy device according to claim 1, characterized in that, The strip sensor includes a temperature sensor or a pressure sensor; Alternatively, the strip sensor may include a temperature sensor and a pressure sensor, and there may be multiple temperature sensors and multiple pressure sensors; the temperature sensors and the pressure sensors may be arranged alternately in sequence.

5. The mesh phototherapy device according to claim 3, characterized in that, The phototherapy luminescent layer and the protective layer also include a water-oxygen barrier layer, which is used to prevent water and oxygen from damaging the organic luminescent material. The material of the water and oxygen barrier layer includes at least one of aluminum oxide, silicon oxide, titanium oxide, and zirconium oxide.

6. The mesh phototherapy device according to claim 4, characterized in that, The material of the substrate layer includes at least one of polyethylene terephthalate, polymethyl methacrylate, cellulose, fibroin, acrylic acid and polydimethylsiloxane; The pressure sensor is made of carbon nanotubes and polylactic acid; the temperature sensor is made of 1-butyl-3-methylimidazolium chloride and acrylic acid. The material of the protective layer includes perylene.

7. The mesh phototherapy device according to claim 1, characterized in that, The width of the substrate strip ranges from 1mm to 1cm; the width of the gap between two adjacent substrate strips ranges from 1mm to 1cm. The width of the strip sensor ranges from 1mm to 1cm; the width of the gap between two adjacent strip sensors ranges from 1mm to 1cm. The pore area of ​​the mesh structure ranges from 1 mm. 2 ~1cm 2 .

8. The mesh phototherapy device according to claim 3, characterized in that, Each of the light-emitting strips includes: Substrate; A first electrode layer is located on the side of the substrate away from the substrate layer; the first electrode layer includes a plurality of first electrodes, which are arranged at intervals along the direction in which the light-emitting strip extends. An organic light-emitting material layer is located on the side of the first electrode layer away from the substrate; The second electrode layer is located on the side of the organic light-emitting material layer away from the substrate; the second electrode layer includes a plurality of second electrodes, which are disposed in a one-to-one correspondence with the first electrodes; An encapsulation layer is located on the side of the second electrode layer away from the substrate.

9. The mesh phototherapy device according to claim 8, characterized in that, In the extension direction of the light-emitting strip, the first electrodes located in the same light-emitting strip are connected in series or in parallel in sequence; after the first electrodes in each light-emitting strip are connected in series or in parallel in sequence, they are connected to a first external electrode; different first external electrodes are connected to different first power output terminals; In the arrangement direction of the plurality of light-emitting strips, the second electrodes of two adjacent light-emitting strips are electrically connected; the second electrodes of all the light-emitting strips are connected in series or in parallel in the arrangement direction of the light-emitting strips and then connected to a corresponding second external electrode; different second external electrodes are connected to different second power output terminals.

10. A method for preparing a mesh phototherapy device, characterized in that, For forming the mesh phototherapy device according to any one of claims 1-9, comprising: A 3D printed substrate layer; the substrate layer includes a plurality of substrate strips extending along a first direction; the plurality of substrate strips are arranged sequentially at intervals along a second direction; the first direction and the second direction intersect each other; A sensor layer is 3D printed on one side of the substrate layer; the sensor layer includes a plurality of strip sensors extending along the second direction; the plurality of strip sensors are arranged at intervals along the first direction; wherein, the substrate layer and the sensor layer form a mesh structure; A phototherapy luminescent layer is 3D printed on the side of the sensor layer away from the substrate layer; wherein the light-emitting surface of the phototherapy luminescent layer is the surface away from the substrate layer; A protective layer is formed; the protective layer is located at least on the side of the phototherapy luminescent layer away from the substrate; the protective layer is used to protect the phototherapy luminescent layer.

Images