An atomized base fluid, an atomized fluid, and a method of reducing small particle size aerosol particles

Abstract

The application provides the field of electronic cigarettes, in particular to an atomization base liquid, an atomization liquid and a method for reducing small particle size aerosol particles, the atomization base liquid comprising one or more combinations of propylene glycol, glycerol, water and ethanol, characterized in that it further comprises 1,3-dihydroxyacetone, wherein the mass fraction of 1,3-dihydroxyacetone is 5-50%. The atomized particles of the electronic cigarette aerosol containing the atomization base liquid will be concentrated in two particle size ranges; the small particle size aerosol can make the smoker quickly satisfied, the amount of smaller particle size aerosol is reduced, and the influence on alveoli is reduced. The large particle size aerosol can bring better taste to the smoker.

Description

Technical Field

[0001] This application relates to the field of electronic cigarettes, specifically to an atomizing base liquid, an atomizing liquid, and a method for reducing small-diameter aerosol particles. Background Technology

[0002] Currently, e-cigarettes are becoming increasingly common in the market, but different particles in e-cigarettes have different sedimentation rates in the human respiratory tract.

[0003] Large-diameter aerosols mainly settle in the upper respiratory tract, such as the nose, pharynx, and larynx. Large-diameter aerosol particles have a more significant impact on sensory quality than small-diameter aerosol particles. By adjusting the particle size distribution of aerosols, the sensory quality of smoke can be significantly altered, providing cigarette smokers with different sensory experiences.

[0004] Small-diameter aerosols mainly settle in the lower respiratory tract, such as the trachea, bronchi, and alveoli. The deposited areas of small-diameter aerosols are more easily absorbed, providing a quick sense of satisfaction. By adjusting the particle size distribution of aerosols, the smoker's needs can be quickly improved, avoiding excessive inhalation due to slow brain feedback.

[0005] When too many particles in an e-cigarette are in the large particle size range, although they can provide smokers with a more noticeable sensory experience, they cannot be inhaled quickly. When too many particles are in the small particle size range, not only will they fail to provide a noticeable sensory experience, but if they are too small, a large amount will enter the alveoli, which will have a negative impact on the lungs.

[0006] There is a lack in this field of electronic atomizing liquids that can satisfy taste requirements, achieve rapid absorption, and avoid excessive aerosol entry into the alveoli that could have a significant impact on the lungs. Summary of the Invention

[0007] To address these technical problems, this invention provides 1,3-dihydroxyacetone, a substance that can adjust and reduce small particle size in e-cigarette aerosols. 1,3-Dihydroxyacetone is a naturally occurring ketose and is characterized by being harmless, safe, biodegradable, promoting brain development, and preventing heart disease. It is widely used in food, medicine, cosmetics, health products, and animal feed. The use of 1,3-dihydroxyacetone as an ingredient in e-cigarettes is rarely reported, and existing technologies do not suggest its ability to reduce small particle size, nor do they indicate its potential to improve taste in e-cigarettes.

[0008] When this substance is present, the concentration of atomized particles smaller than 0.1 micrometers in e-cigarette aerosols will be significantly reduced, especially the concentration of particles with a diameter of 0.01-0.03 micrometers, which will greatly reduce the number of particles deposited in the alveoli. In some embodiments of the present invention, the particle size is mainly concentrated in two particle size ranges; aerosols with a smaller particle size range can provide users with rapid satiating effects, and the reduction in the amount of even smaller particle size aerosols reduces the impact on the alveoli. Aerosols with a larger particle size range can provide users with a better taste.

[0009] Specifically, the present invention provides an electronic atomizing base liquid, comprising one or more combinations of propylene glycol, glycerol, water, and ethanol, and further comprising 1,3-dihydroxyacetone, wherein the mass fraction of the 1,3-dihydroxyacetone is 5-50%.

[0010] In some embodiments, one or more combinations of propylene glycol, glycerol, water, and ethanol include the following options:

[0011] i: Propylene glycol; ii: Glycerol; iii: Water; iv: Ethanol; v: Propylene glycol, Glycerol; vi: Propylene glycol, Water; vii: Glycerol, Water; viiii: Propylene glycol, Ethanol; ix: Glycerol, Ethanol; x: Propylene glycol, Glycerol, Water; xi: Propylene glycol, Glycerol, Ethanol; or xii: Propylene glycol, Glycerol, Water, Ethanol.

[0012] In some embodiments, the mass fraction of the 1,3-dihydroxyacetone is 10%-40%; optionally, the mass fraction of the 1,3-dihydroxyacetone is 15%-35%.

[0013] In some embodiments, the propylene glycol has a mass fraction of 0%-50%; the glycerol has a mass fraction of 0%-50%; the water has a mass fraction of 0%-50%; and the ethanol has a mass fraction of 0%-50%. Optionally, the propylene glycol has a mass fraction of 0%-30%; the glycerol has a mass fraction of 30%-50%; the water has a mass fraction of 0%-20%; and the ethanol has a mass fraction of 0%-20%.

[0014] When this substance is present, the concentration of atomized particles smaller than 0.1 micrometers in e-cigarette aerosol will be greatly reduced, especially the concentration of particles with a diameter of 0.01-0.03 micrometers, which greatly reduces the number of particles deposited in the alveoli.

[0015] On the other hand, the present invention also provides an electronic atomizing liquid, including the electronic atomizing base liquid described in the present invention.

[0016] In some embodiments, the e-liquid further includes nicotine or nicotine salts, wherein the final concentration of nicotine in the e-liquid is 0%-20% by mass; optionally, the final concentration of nicotine in the e-liquid is 1%-10% by mass.

[0017] In some embodiments, the nicotine salt is one or more combinations of nicotine malonate, nicotine citrate, nicotine 2-ethylbutyrate, nicotine acetate, nicotine adipate, nicotine benzoate, nicotine butyrate, nicotine cinnamate, nicotine cycloheptane-carboxylate, nicotine fumarate, nicotine glycolate, nicotine hexanoate, nicotine lactate, nicotine levulinate, nicotine malate, nicotine myristate, nicotine octanoate, nicotine oxalate, nicotine propionate, nicotine pyruvate, nicotine succinate, and nicotine undecanoate; optionally, the nicotine salt is one or more combinations of benzoic acid nicotine salt, levulinic acid nicotine salt, and lactic acid nicotine salt.

[0018] In some embodiments, the electronic atomizing liquid further includes a flavoring substance, which is one or more of a sweetener, a cooling agent, an acidulant, a flavoring agent, or a tobacco extract, and the flavoring substance has a mass fraction of 0.5-30%.

[0019] In some embodiments, the sweetener has a mass fraction of 0-10%; the acidulant has a mass fraction of 0-5%; the cooling agent has a mass fraction of 0-10%; the flavoring has a mass fraction of 0-20%; and the tobacco extract has a mass fraction of 0-10%.

[0020] In some embodiments, the particle size of e-cigarette aerosols is primarily concentrated in the range greater than 0.03 micrometers; in other embodiments, the particle size is primarily within two ranges. Aerosols with a smaller particle size range provide rapid satiating for the user, while a reduction in the amount of even smaller aerosols decreases the impact on the alveoli. Aerosols with a larger particle size range provide a better taste experience for the user.

[0021] The present invention also provides a method for reducing small-diameter aerosol particles, comprising the following steps:

[0022] Add 5-50% by mass of 1,3-dihydroxyacetone to the electronic atomizing liquid and stir to dissolve to obtain the first solution;

[0023] The first solution is injected into the electronic atomizer.

[0024] Detailed information

[0025] For the purposes of the detailed description below, it should be understood that various alternative variations and sequences of steps may be employed in this application unless expressly stated otherwise. Furthermore, except in any operational example or otherwise indicated, all figures representing the amounts of ingredients used, for example, in the specification and claims, should be understood to be modified in all cases by the term “about.” Therefore, unless indicated to the contrary, the numerical parameters set forth in the following specification and appended claims are approximate values ​​varying according to the desired performance to be obtained in this application. At least not in an attempt to limit the application of the doctrine of equivalents to the scope of the claims, each numerical parameter should be interpreted at least according to the number of significant figures reported and by applying ordinary rounding techniques.

[0026] An embodiment of the present invention provides an atomizing base liquid comprising one or more combinations of propylene glycol, glycerol, water, and ethanol, and further comprising 1,3-dihydroxyacetone, wherein the mass fraction of the 1,3-dihydroxyacetone is 5-50%.

[0027] When this substance is present, the concentration of atomized particles smaller than 0.1 micrometers in e-cigarette aerosols is significantly reduced, particularly the concentration of particles with a diameter of 0.01-0.03 micrometers, greatly reducing the number of particles deposited in the alveoli. In some embodiments, the particle size is mainly concentrated in two ranges; the smaller particle size range of aerosols provides the user with rapid satiation, and the reduced amount of even smaller particle size aerosols decreases the impact on the alveoli. The larger particle size range of aerosols provides the user with a better taste.

[0028] In some embodiments, one or more combinations of propylene glycol, glycerol, water, and ethanol include the following options:

[0029] i: Propylene glycol; ii: Glycerol; iii: Water; iv: Ethanol; v: Propylene glycol and glycerol; vi: Propylene glycol and water;

[0030] vii: glycerol, water; viiii: propylene glycol, ethanol; ix: glycerol, ethanol; x: propylene glycol, glycerol, water; xi: propylene glycol, glycerol, ethanol; or xii: propylene glycol, glycerol, water, ethanol.

[0031] In some embodiments, the e-cigarette base liquid comprises propylene glycol and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises propylene glycol and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises propylene glycol and 15-35% by mass of 1,3-dihydroxyacetone.

[0032] In some embodiments, the e-cigarette base liquid comprises glycerol and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises glycerol and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises glycerol and 15-35% by mass of 1,3-dihydroxyacetone.

[0033] In some embodiments, the electronic atomizing base fluid comprises water and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises water and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises water and 15-35% by mass of 1,3-dihydroxyacetone.

[0034] In some embodiments, the electronic atomizing base fluid comprises ethanol and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises ethanol and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises ethanol and 15-35% by mass of 1,3-dihydroxyacetone.

[0035] In some embodiments, the e-cigarette base liquid comprises propylene glycol, glycerol, and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises propylene glycol, glycerol, and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the e-cigarette base liquid comprises propylene glycol, glycerol, and 15-35% by mass of 1,3-dihydroxyacetone.

[0036] In some embodiments, the electronic atomizing base fluid comprises propylene glycol, glycerol, water, and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises propylene glycol, glycerol, water, and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base fluid comprises propylene glycol, glycerol, water, and 15-35% by mass of 1,3-dihydroxyacetone.

[0037] In some embodiments, the electronic atomizing base liquid comprises propylene glycol, glycerol, water, ethanol, and 5-50% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base liquid comprises propylene glycol, glycerol, water, ethanol, and 10-40% by mass of 1,3-dihydroxyacetone. In some embodiments, the electronic atomizing base liquid comprises propylene glycol, glycerol, water, ethanol, and 15-35% by mass of 1,3-dihydroxyacetone.

[0038] In some embodiments, the 1,3-dihydroxyacetone has a mass fraction of 10-40%. In other embodiments, the 1,3-dihydroxyacetone has a mass fraction of 15-35%. In still other embodiments, the 1,3-dihydroxyacetone has a mass fraction of 15%, 25%, or 35%.

[0039] In some embodiments, the propylene glycol has a mass fraction of 0-50%. In other embodiments, the propylene glycol has a mass fraction of 0-30%. In still other embodiments, the propylene glycol has a mass fraction of 5-20%. In yet other embodiments, the propylene glycol has a mass fraction of 10-15%. In still other embodiments, the propylene glycol has a mass fraction of 10% or 15%.

[0040] In some embodiments, the glycerol has a mass fraction of 0%-50%. In other embodiments, the glycerol has a mass fraction of 30%-50%. In still other embodiments, the glycerol has a mass fraction of 35%-45%. In yet another embodiment, the glycerol has a mass fraction of 40%.

[0041] In some embodiments, the water has a mass fraction of 0-50%. In other embodiments, the water has a mass fraction of 0-20%.

[0042] In some embodiments, the ethanol has a mass fraction of 0-50%. In other embodiments, the ethanol has a mass fraction of 0-20%. In still other embodiments, the ethanol has a mass fraction of 5-15%. In yet another embodiment, the ethanol has a mass fraction of 5%-10%.

[0043] In some embodiments, the present invention also provides an electronic atomizing fluid, comprising the electronic atomizing base fluid described in the present invention.

[0044] In some embodiments, the e-liquid further includes nicotine or nicotine salts, wherein the final concentration of nicotine in the e-liquid is 0%-20% by mass; optionally, the final concentration of nicotine in the e-liquid is 1%-10% by mass; optionally, the final concentration of nicotine in the e-liquid is 1%-5% by mass.

[0045] In some embodiments, the nicotine salt is nicotine malonate, nicotine citrate, nicotine 2-ethylbutyrate, nicotine acetate, nicotine adipate, nicotine benzoate, nicotine butyrate, nicotine cinnamate, nicotine cycloheptane-carboxylate, nicotine fumarate, nicotine glycolate, nicotine hexanoate, nicotine lactate, nicotine acetylacetonate, nicotine malate, nicotine myristate, nicotine caprylate, nicotine oxalate, nicotine propionate, nicotine pyruvate, nicotine succinate, and nicotine undecanoate.

[0046] In some embodiments, the nicotine salts are: benzoic acid nicotine salt, acetylated propionic acid nicotine salt, and lactic acid nicotine salt.

[0047] In some embodiments, the electronic atomizing liquid further includes a flavoring substance, which is one or more of a sweetener, a cooling agent, an acidulant, a flavoring agent, or a tobacco extract, and the flavoring substance has a mass fraction of 0.5-30%.

[0048] In some embodiments, the sweetener has a mass fraction of 0-10%; the acidulant has a mass fraction of 0-5%; the cooling agent has a mass fraction of 0-10%; the flavoring has a mass fraction of 0-20%; and the tobacco extract has a mass fraction of 0-10%.

[0049] In some embodiments, the sweetener in the e-liquid has a mass fraction of 0-10%. In other embodiments, the sweetener in the e-liquid has a mass fraction of 0-5%. In still other embodiments, the sweetener in the e-liquid has a mass fraction of 0-0.1%.

[0050] The sweeteners include, but are not limited to, xylitol, maltose, stevia, rhamnose, trehalose, erythritol, lactose, galactose, stevia, licorice, disodium glycyrrhizate, tripotassium and trisodium glycyrrhizate, saccharin, acetylsupan potassium, Advantame, neotame, aspartame, neohesperidin dihydrocarboxone, neohesperidin dihydrochalcone, and sucralose.

[0051] In some embodiments, the acidulant in the e-liquid has a mass fraction of 0-5%. In other embodiments, the acidulant in the e-liquid has a mass fraction of 0-1%. In still other embodiments, the acidulant in the e-liquid has a mass fraction of 0-0.1%.

[0052] The acidulants include, but are not limited to, acetic acid and propionic acid.

[0053] In some embodiments, the mass fraction of the cooling agent in the electronic atomizing fluid is 0-10%. In other embodiments, the mass fraction of the cooling agent in the electronic atomizing fluid is 0-5%. In still other embodiments, the mass fraction of the cooling agent in the electronic atomizing fluid is 0-0.05%.

[0054] The cooling agents include, but are not limited to, menthol, menthone, isomenthone, 1-menthol lactate, WS-23 (N,2,3-trimethyl-2-isopropylbutyramide), WS-3 (N-ethyl-p-menthyl-3-carboxamide), WS-5 (N-(ethoxycarbonylmethyl)-p-alkyl-3-carboxamide), and WS-12 (N-(4-methoxyphenyl)-p-menthyl-3-carboxamide).

[0055] In some embodiments, the flavoring in the electronic atomizing fluid has a mass fraction of 0-20%. In other embodiments, the flavoring in the electronic atomizing fluid has a mass fraction of 0-10%.

[0056] The flavorings include, but are not limited to, fruit flavorings, floral flavorings, tea flavorings, milk flavorings, and tobacco flavorings.

[0057] In some embodiments, the mass fraction of tobacco extract in the e-liquid is 0-10%. In other embodiments, the mass fraction of tobacco extract in the e-liquid is 0-5%.

[0058] The tobacco extract is a herbal extract with a tobacco flavor obtained by extracting tobacco as a raw material.

[0059] The present invention also provides a method for reducing small-diameter aerosol particles, comprising the following steps:

[0060] Add 5-50% by mass of 1,3-dihydroxyacetone to the electronic atomizing liquid and stir to dissolve to obtain the first solution;

[0061] The first solution is injected into the electronic atomizer.

[0062] The present invention also provides a method for reducing small-diameter aerosol particles, comprising the following steps:

[0063] Add one or more of nicotine or nicotine salts and flavoring substances to an electronic atomization base liquid containing 5-50% 1,3-dihydroxyacetone in the final solution, and stir to dissolve to obtain a first solution;

[0064] The first solution is injected into the electronic atomizer.

[0065] In this invention, the term "nm" is used to represent a numerical range, that is, the range from the number n to m. In some embodiments, the range "nm" includes n, m, and all numbers between n and m. In other embodiments, the range "nm" includes m and all numbers between n and m; in some embodiments, the range "nm" includes n and all numbers between n and m; in some embodiments, the range "nm" includes all numbers between n and m.

[0066] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0067] Unless otherwise stated or there is a clear conflict in the context, the articles “a,” “an,” and “described” as used herein are intended to include “at least one” or “one or more.” Therefore, these articles as used herein refer to articles for one or more (i.e., at least one) objects. For example, “a component” refers to one or more components, meaning that more than one component may be considered for use or adoption in the implementation of the described embodiments. Attached Figure Description

[0068] Figure 1 Results of aerosol particle size test in Example 1

[0069] Figure 2 Results of aerosol particle size test in Example 2

[0070] Figure 3 Results of aerosol particle size test in Example 3

[0071] Figure 4 Results of aerosol particle size test in Example 4

[0072] Figure 5 Results of aerosol particle size test in Example 5

[0073] Figure 6 Results of aerosol particle size test in Comparative Example 1

[0074] Figure 7 Comparative Example 2: Aerosol Particle Size Test Results

[0075] Figure 8 Results of aerosol particle size test in Comparative Example 3

[0076] Figure 9 Results of aerosol particle size test in Comparative Example 4

[0077] Figure 10 Results of aerosol particle size test in Comparative Example 5

[0078] Figure 11 Particle size test results of 1,2-propanediol in single solvent and 1,2-propanediol containing 1,3-dihydroxyacetone (15%).

[0079] Figure 12 : An external view of the smoking machine used in this invention Detailed Implementation

[0080] To more clearly illustrate the solution of this application, the following specific embodiments are provided. Exemplary embodiments of this disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of this disclosure are shown in the drawings, it should be understood that this disclosure can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of this disclosure and to fully convey the scope of this disclosure to those skilled in the art.

[0081] Preparation Example:

[0082] Example 1

[0083] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 8g of glycerol, 7.9g of propylene glycol, and 3g of 1,3-dihydroxyacetone (monomer 102) into a sample bottle (15% by mass of 1,3-dihydroxyacetone). Shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, evaluate the sensory quality of the e-liquid and test the aerosol particle size. The aerosol particle size test results are as follows: Figure 1 .

[0084] Example 2

[0085] Weigh out 0.4g of tobacco extract, 0.7g of nicotine benzoate, 8g of glycerol, 5.9g of propylene glycol, and 5g of 102 monomer (1,3-dihydroxyacetone) and place them in a sample bottle (1,3-dihydroxyacetone mass fraction 25%). Shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, perform sensory quality evaluation of the e-liquid and test the aerosol particle size of the smoke. The aerosol particle size test results are as follows: Figure 2 .

[0086] Example 3

[0087] Weigh out 0.4g of tobacco extract, 0.7g of nicotine benzoate, 8g of glycerol, 3.9g of propylene glycol, and 7g of 102 monomer and place them in a sample bottle (1,3-dihydroxyacetone, 35% by mass). Shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, perform sensory quality evaluation of the e-liquid and test the aerosol particle size. The aerosol particle size test results are as follows: Figure 3 As shown.

[0088] Example 4

[0089] Weigh out 0.4g of tobacco extract, 2g of water, 0.7g of nicotine benzoate, 8g of glycerol, 5.9g of propylene glycol, and 3g of 102 monomer and place them in a sample bottle (15% by mass of 1,3-dihydroxyacetone). Shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, perform sensory quality evaluation of the e-liquid and test the aerosol particle size of the smoke. The aerosol particle size test results are as follows: Figure 4 .

[0090] Example 5

[0091] Weigh out 0.4g of tobacco extract, 2g of water, 2g of 95% ethanol, 0.7g of nicotine benzoate, 8g of glycerol, 3.9g of propylene glycol, and 3g of 102 monomer and place them in a sample bottle (1,3-dihydroxyacetone, 22.9% by mass). Shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, perform sensory quality evaluation of the e-liquid and test the aerosol particle size. The aerosol particle size test results are as follows: Figure 5 .

[0092] Example 6

[0093] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 17.9g of propylene glycol, and 1g of 102 monomer into a sample bottle (1,3-dihydroxyacetone mass fraction 5%), shake well for 10 minutes to obtain e-cigarette liquid, inject the e-cigarette liquid into 3 disposable cotton wick e-cigarettes respectively, and then conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0094] Example 7

[0095] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 8.9g of propylene glycol, and 10g of 102 monomer into a sample bottle (1,3-dihydroxyacetone mass fraction 50%), shake well for 10 minutes to obtain e-cigarette liquid, inject the e-cigarette liquid into 3 disposable cotton wick e-cigarettes respectively, and then conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0096] Example 8

[0097] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 16.9g of water, and 2g of 102 monomer into a sample bottle (10% by mass of 1,3-dihydroxyacetone). Shake well for 10 minutes to obtain an e-cigarette liquid. Inject the e-cigarette liquid into three disposable cotton wick e-cigarettes. Then, conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0098] Example 9

[0099] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 9.9g of ethanol, and 9g of 102 monomer into a sample bottle (1,3-dihydroxyacetone mass fraction 45%), shake well for 10 minutes to obtain e-cigarette liquid, inject the e-cigarette liquid into 3 disposable cotton wick e-cigarettes respectively, and then conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0100] Example 10

[0101] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 17.4g of ethanol, and 1.5g of 102 monomer into a sample bottle (1,3-dihydroxyacetone mass fraction 7.5%), shake well for 10 minutes to obtain e-cigarette liquid, inject the e-cigarette liquid into 3 disposable cotton wick e-cigarettes, and then conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0102] Example 11

[0103] Weigh 0.4g of tobacco extract, 0.7g of nicotine benzoate, 5g of water, 12.9g of glycerol, and 1g of 102 monomer into a sample bottle (1,3-dihydroxyacetone mass fraction 5%), shake well for 10 minutes to obtain e-cigarette liquid, inject the e-cigarette liquid into 3 disposable cotton wick e-cigarettes, and then conduct sensory quality evaluation of the e-liquid and test the particle size of the smoke aerosol.

[0104] Preparation of comparative examples:

[0105] Comparative Example 1

[0106] Weigh out 0.4g of tobacco extract, 0.7g of nicotine benzoate, 8g of glycerol, and 10.9g of propylene glycol, place them in a sample bottle, and shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, evaluate the sensory quality of the e-liquid and test the aerosol particle size. The aerosol particle size test results are as follows: Figure 6 .

[0107] Comparative Example 2

[0108] Weigh out 0.4g of tobacco extract, 2g of water, 0.7g of nicotine benzoate, 8g of glycerol, and 8.9g of propylene glycol, place them in a sample bottle, and shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes. Then, perform sensory quality evaluation of the e-liquid and test the aerosol particle size. The aerosol particle size test results are as follows: Figure 7 .

[0109] Comparative Example 3

[0110] Weigh out 2g of water, 8g of glycerol, and 10g of propylene glycol, place them in a sample bottle, and shake well for 10 minutes to obtain the e-liquid. Inject the e-liquid into three disposable cotton wick e-cigarettes, and then conduct sensory quality evaluation of the e-liquid and aerosol particle size testing. The aerosol particle size test results are as follows: Figure 8 .

[0111] Comparative Example 4

[0112] Weigh out 0.4g of tobacco extract, 2g of water, 2g of 95% ethanol, 0.7g of nicotine benzoate, 8g of glycerol, and 6.9g of propylene glycol. Place them in a sample bottle, shake well for 10 minutes, and inject the e-liquid into disposable cotton wick e-cigarettes. Fill three e-liquids with the e-liquid. Then, conduct sensory quality evaluation of the e-liquid and test the aerosol particle size distribution. Aerosol particle size test results: The aerosol particle size test results are as follows... Figure 9 .

[0113] Comparative Example 5

[0114] Weigh out 2g of water, 2g of 95% ethanol, 8g of glycerol, and 8g of propylene glycol, place them in a sample bottle, shake well for 10 minutes, and then inject the e-liquid into three disposable cotton wick e-cigarettes. Afterward, conduct sensory quality evaluation of the e-liquid and test the aerosol particle size distribution. The aerosol particle size test results are shown below. Figure 10 .

[0115] Particle size testing experiment

[0116] Method: A suction machine was used to draw in aerosol particles, and a particle size analyzer was used to test the particle size of the aerosol.

[0117] Smoke extractor: Feihong FH-Y1216 model smoke extractor, 3-stop-5-smoke cycle, 55ml suction capacity, square wave.

[0118] Particle size analyzer: PALAS DEMC2000 scanning electromobility particle size analyzer (Germany), scanning range 10-1200 nm, diluted 10000 times. Figure 12 .

[0119] Test results are as follows Figures 1-10As shown in the figure, adding 1,3-dihydroxyacetone as described in this invention to various solvents can reduce the number of small-diameter aerosol particles and make the distribution of aerosols in the intermediate particle size more concentrated.

[0120] To further confirm the effect of 1,3-dihydroxyacetone in reducing small-diameter aerosol particles and making the distribution of aerosols with intermediate particle sizes more concentrated in the e-cigarette vaporizing liquid, this invention also conducted verification experiments:

[0121] The particle size of 1,2-propanediol in a single solvent, as well as 1,2-propanediol containing 1,3-dihydroxyacetone (15%), was investigated. The results are as follows: Figure 11 As shown, peak 1# is composed of 1,2-propanediol (particle size range 0.01-0.1 μm) in a single solvent, while peak 2# is composed of 1,2-propanediol containing 1,3-dihydroxyacetone (15%) (particle size range 0.03-0.3 μm). Clearly, 1,3-dihydroxyacetone can reduce the number of small-diameter aerosol particles, making the distribution of aerosols in the intermediate particle size range more concentrated.

[0122] Meanwhile, the present invention also verified and compared the particle size changes of Examples 7, 8, 9, 10, and 11 with the corresponding examples without the addition of 102 monomer. The examples with the addition of 102 monomer showed the same particle size change trend as the corresponding examples without the addition, that is, the concentration of ions with a particle size of less than 0.03 micrometers decreased.

[0123] The present invention also includes verification experiments. Examples 1-11, which added 0.2% of the original total mass fraction of sweetener (neotame) and 0.5% of the original total mass fraction of cooling agent (WS-23), were compared with the particle size of examples 1-11, which added 0.2% of the original total mass fraction of sweetener (neotame) and 0.5% of the original total mass fraction of cooling agent (WS-23) but did not add 102 monomer. The examples with added 102 monomer and the corresponding examples without added 102 monomer showed the same trend in particle size change, that is, the concentration of ions with a particle size of less than 0.03 micrometers decreased.

[0124] Taste test experiment

[0125] method:

[0126] The e-cigarette liquid samples from the above embodiments and the comparative e-cigarette liquid samples were added to an e-cigarette device with a power of 6.5W. A blind tasting evaluation was conducted using a large-circulation inhalation method. A professional sensory quality evaluation team of 20 people performed sensory evaluations. The taste evaluation criteria are shown in Table 1 below, mainly including the following evaluation indicators: aroma concentration, irritation (off-flavors), vapor volume, aftertaste, throat hit, vapor humidity, balance, and satisfaction. Each evaluation indicator has a maximum score of 10 points, and each indicator is scored in units of 0.5 points. Except for irritation (off-flavors), which is scored negatively, the other indicators are scored positively. The test results are shown in Table 2.

[0127] The meaning of the 8 indicators is as follows:

[0128] Aroma concentration: The intensity of the overall smoke perceived by the nasal cavity and oral cavity;

[0129] Irritation: The irritating sensory experience of the vapor produced by e-cigarette liquid in the mouth, throat, and nasal cavity, such as a grainy sensation, a pricking sensation, and impurities;

[0130] Vapor volume: The total amount of aerosol formed after the e-cigarette liquid is atomized, as well as the amount of vapor felt through the mouth and visible after exhalation;

[0131] Aftertaste: The duration of taste in the mouth after inhaling e-cigarette vaporized liquid;

[0132] Throat hit sensation: The physical sensory intensity of the impact of smoke on the throat after inhalation of aerosols;

[0133] Smoke humidity: The degree of dryness or wetness of smoke droplet molecules perceived by the oral cavity and nasal cavity;

[0134] Harmony: The uniformity and harmony of the aroma after the e-cigarette liquid is vaporized;

[0135] The feeling of satisfaction, or the short-term excitement in the brain resulting from the absorption of nicotine by the lungs after the same number of doses, can manifest as symptoms such as numbness or dizziness in the head.

[0136] Table 1 Sensory Quality Evaluation Criteria

[0137]

[0138]

[0139] Table 2 Sensory test results

[0140]

[0141] As shown in Table 2, the electronic cigarettes involved in the embodiments of the present invention have the characteristics of distinct aroma, harmonious smoke, rich and full-bodied smoke, moderate stimulation, clean mouth, a new sweetness at the end of the smoke, and a fuller, more lingering, and delicate smoke compared to the comparative sample. Therefore, it can be reasonably concluded that 1,3-dihydroxyacetone plays a role in harmonizing the taste of electronic cigarettes. Aerosol with a large particle size range can provide the user with a better taste experience.

[0142] As shown in the attached figure, the addition of 1,3-dihydroxyacetone can improve the particle size distribution of aerosols, reduce small-particle aerosols, reduce the impact on alveoli, and improve the safety of e-cigarettes.

[0143] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. An electronic atomizing fluid, comprising one or more combinations of propylene glycol, glycerol, water, and ethanol, characterized in that, It also includes 1,3-dihydroxyacetone, wherein the mass fraction of the 1,3-dihydroxyacetone is 5%-50%; It also includes tobacco extract and nicotine benzoate, wherein the mass fraction of the tobacco extract is no more than 5%, and the mass fraction of the nicotine benzoate is 1-5%, and the tobacco extract is a herbal extract with tobacco flavor obtained by extracting tobacco as raw material.

2. The electronic atomizing fluid according to claim 1, characterized in that, The mass fraction of the 1,3-dihydroxyacetone is 10%-40%.

3. The electronic atomizing fluid according to claim 2, characterized in that, The mass fraction of the 1,3-dihydroxyacetone is 15%-35%.

4. The electronic atomizing fluid according to claim 1, characterized in that, The mass fraction of propylene glycol does not exceed 50%; the mass fraction of glycerol does not exceed 50%; the mass fraction of water does not exceed 50%; and the mass fraction of ethanol does not exceed 50%.

5. The electronic atomizing fluid according to claim 4, characterized in that, The mass fraction of propylene glycol is no more than 30%; the mass fraction of glycerol is 30%-50%; the mass fraction of water is no more than 20%; and the mass fraction of ethanol is no more than 20%.

6. The electronic atomizing fluid according to claim 1, characterized in that, It also includes flavoring substances, which are one or more of sweeteners, cooling agents, acidulants, flavorings or tobacco extracts, and the flavoring substances have a mass fraction of 0.5-30%.

7. The electronic atomizing fluid according to claim 6, characterized in that, The mass fraction of the sweetener does not exceed 10%; the mass fraction of the acidulant does not exceed 5%; the mass fraction of the cooling agent does not exceed 10%; and the mass fraction of the flavoring does not exceed 20%.

8. A method for reducing small-diameter aerosol particles, characterized in that, Includes the following steps: The electronic atomizing liquid according to any one of claims 1-7 is injected into the electronic atomizer.

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