Nucleic acid detection sampling device

Abstract

The present application relates to a kind of medical supplies, specifically disclose a nucleic acid detection sampling device, it includes throat swab and sampling tube, throat swab is by stem, cotton head and push ring constitute;Sampling tube is by tube, inner cover and tube cap constitute, inner cover and tube upper end port thread cooperation, inner cover is equipped with elastic rubber nozzle on;Cotton head and push ring can enter tube by elastic rubber nozzle, upward pull stem, push ring and cotton head will be kept in tube;Tube cap top is equipped with check column and check head, tube cap and inner cover between being equipped with kiss part;Tube cap moves to check head after being located under elastic rubber nozzle under, tube cap cannot slide upward, tube cap and inner cover cannot relative rotation.This throat swab can effectively reduce use cost, reduce resource waste, throat swab overall strength is high, operation safety;Cotton head is easy to separate after sampling is completed, can significantly improve sampling efficiency;Nucleic acid detection sampling device can prevent sample splashing, spill out when being used, reduce even avoid aerosol, improve the operation safety.

Description

TECHNICAL FIELD

[0001] The present application relates to a medical product, in particular to a sampling assembly used in nucleic acid detection. TECHNICAL BACKGROUND

[0002] Nucleic acid detection is a commonly used disease detection method in clinical practice, especially during the epidemic period of infectious diseases. The nucleic acid detection method can quickly and efficiently screen out infected cases, which is one of the important measures for epidemic prevention and control. At present, when screening respiratory infectious disease infected persons through nucleic acid detection, a throat swab is usually used for sampling, which has certain shortcomings in actual operation.

[0003] Firstly, the existing throat swab is usually composed of a rod body and a cotton head, and is a disposable product. During the period when the epidemic is more serious, nucleic acid detection needs to be carried out on a large number of people at a high frequency, which undoubtedly forms a large cost burden. The used throat swab is eventually treated as medical waste, which causes resource waste and environmental pollution. In addition, since the existing throat swab is designed for one-time use, in order to reduce costs, the slender rod body is usually made of inexpensive materials, and the overall strength is low, which makes the hand feeling poor during actual sampling operation, and it is often difficult to accurately control the sampling force and sampling position, affecting the sampling efficiency and effect.

[0004] Secondly, the existing throat swab usually has a breaking part on the rod body near the cotton head. After collecting the secretions of the throat of the examinee, the rod body can be broken at the breaking part, so that the cotton head with the sample can be temporarily collected and stored in the sampling tube for subsequent detection. On the one hand, the existence of the breaking part reduces the overall strength of the rod body, and the throat swab is often broken during the collection of the secretions of the throat, which affects the sampling efficiency and also has certain safety hazards. On the other hand, when breaking the rod body at the breaking part, the end part where the cotton head is located needs to be limited by the cooperation of the cap and the tube, and then the force can be applied to break it. The operation is not convenient, especially when a large number of examinees are sampled in a centralized manner, which seriously affects the operation efficiency. In addition, the process of breaking the rod body in the foregoing manner is difficult to proceed smoothly, which easily causes the sample on the throat swab to splash or generate aerosol, and the broken rod body is also easy to touch other objects or persons.

[0005] Thirdly, in order to improve efficiency and save cost, mixed detection is usually used in detection screening of large-scale personnel, and the cotton heads of multiple swabs collected from multiple persons are collected in a sampling tube during sampling process; the tube body and the cap of the existing sampling tube are usually matched by screwing, in order to avoid mutual pollution between the inside and outside of the sampling tube, the cap needs to be unscrewed every time the cotton head is put into the sampling tube, and the cap is screwed after the cotton head is put into the sampling tube, which is quite troublesome and seriously affects the sampling efficiency; more seriously, in the above-mentioned reciprocating operation which is not convenient, the tube body is likely to slip from the operator's hand in the case that the cap is not screwed, which causes the specimen to be spilled and causes serious safety problems, and the existing sampling tube does not have effective measures to prevent the above-mentioned situation. SUMMARY

[0006] In order to overcome the above-mentioned deficiencies in the prior art, the purpose of the present application is to provide a nucleic acid detection sampling device which is reasonable in structure, convenient to use, especially low in use cost, and is beneficial to improve the operation efficiency and safety.

[0007] In order to achieve the above technical purpose, the technical scheme adopted by the present application is as follows:

[0008] A nucleic acid detection sampling device, comprising a throat swab and a sampling tube, characterized in that:

[0009] The throat swab comprises a rod body, the front end of the rod body is a flat head part with a non-circular cross section, the flat head part is provided with a cotton head wrapping the front end and the outside, and a push ring is sleeved on the rod body and located at the rear side of the flat head part; an external force drives the push ring to move forward, and the push ring pushes the cotton head to slide off from the front end of the rod body;

[0010] The sampling tube is composed of a tube body, an inner cover and a tube cap; the lower end of the tube body is closed and the upper end is open; the inner cover is arranged in the upper end port of the tube body and the two are threadedly matched; an insertion hole is formed in the upper end of the inner cover and the insertion hole is used for passing the cotton head end of a throat swab; the lower side of the insertion hole is provided with an elastic rubber nozzle in the shape of a funnel and the tip of the nozzle is downward; the middle and lower parts of the elastic rubber nozzle are divided into a plurality of equiangularly distributed lip petals; the lip petals are tightly buckled to close the lower end of the insertion hole in the natural state; when the throat swab passes through the insertion hole and moves downward, the lip petals are opened to allow the cotton head and the push ring to enter the tube body; thereafter, if the rod body is pulled upward, the push ring is blocked by the lip petals and cannot move upward, the push ring and the cotton head will be separated from the front end of the rod body and left in the tube body, and the rod body will be pulled out alone; the tube cap is provided with a downwardly extending check column at the top; the lower end of the check column is provided with a tapered check head with a downward tip; a matching joint part is arranged between the tube cap and the inner cover; in the initial state, the tube cap is sleeved on the outer part of the upper end of the tube body and the two are slidingly and sealingly matched; the check head extends into the elastic rubber nozzle through the insertion hole but the lip petals remain buckled; in this state, during the process of driving the tube cap to move downward to abut against the top of the tube body, the check head will open the lip petals and move to the lower side of the elastic rubber nozzle; thereafter, the tube cap cannot slide upward based on the cooperation of the check head and the lip petals; the joint part between the tube cap and the inner cover is matched to prevent the tube cap and the inner cover from rotating relative to each other.

[0011] The use method and working principle of the nucleic acid detection sampling device are as follows:

[0012] According to the standard operation of the throat swab sampling, the throat swab is used to collect the throat secretion of the subject, the cap of the initial state of the sampling tube is pulled off from the tube body, the end with the cotton head of the throat swab is inserted into the insertion hole of the sampling tube, and after the obvious jerk is felt, it is indicated that the cotton head and the push ring have passed through the elastic rubber nozzle and entered the tube body, then the rod body is pulled upward, since the outer diameter of the push ring is certainly larger than the outer diameter of the rod body, the push ring cannot move upward after being stopped by the lip which is tightly attached to the outer side of the rod body, the push ring and the cotton head are separated from the front end of the rod body, so that the collected specimen is left in the tube body and soaked in the preservative, the rod body is separately pulled out and stored in the collection container, after the above operation, the cap is temporarily fitted on the upper end of the tube body for sealing, and the cap does not need to be pressed to the bottom; according to the above mode, the samples collected from different subjects are sequentially put into the tube body, when the number of samples in the tube body reaches the predetermined number required for mixed detection, the cap is fitted on the upper end of the tube body and pressed to the bottom, the check valve is opened to move to the lower side of the elastic rubber nozzle, then the check valve cooperates with the lip to make the cap unable to slide upward, that is, the cap is locked and cannot slide off from the upper end of the tube body, at this time, the sampling tube reaches the sealed state, and the sampling tube with the sealed sample is stored in the transport box for laboratory inspection; in the sealed state, the cap and the tube body are in sliding sealing cooperation, the inner cover is in threaded cooperation with the tube body, the fitting part of the cap and the inner cover is fitted, based on the cooperation mode of the above components, the cap and the inner cover can be removed from the upper end of the tube body by screwing the cap, so that the upper end of the tube body is opened, therefore, the sampling tube is suitable for the existing full-automatic capping and sampling system in the laboratory detection stage; after the nucleic acid sampling is completed by using the throat swab, since the rod body does not change in structure, after being recovered and centrally processed, it can be used for the production of the throat swab disclosed in the application.

[0013] Compared with the prior art, the nucleic acid detection sampling device has the following beneficial technical effects in clinical use:

[0014] After the nucleic acid sampling is completed by using the throat swab, the structure of the rod body remains intact, and after recovery and processing, the rod body can be used for the production of the throat swab again, so as to be recycled, which can effectively reduce the use cost of the throat swab and reduce resource waste and environmental pollution; since the throat swab can reduce the overall use cost through the recycling mode of the rod body, the rod body can be made of high-quality materials, and in addition, the rod body does not need to be pre-broken, so that the cotton swab has good strength as a whole, the hand feeling is better during sampling operation, which is beneficial to accurately control the sampling force and sampling position, and at the same time, the accidental breakage during sampling process is effectively avoided, and the operation safety is improved; during the nucleic acid sampling process, after the throat swab is used to collect the throat secretions of the examinee, the cotton head of the throat swab is inserted into the pipe body through the insertion hole, and then the rod body is pulled out, so that the cotton head carrying the nucleic acid sample can be separated into the pipe body, which is convenient, fast, time-saving and efficient; in addition, the pipe cap and the pipe body are matched in a sliding sealing mode, so that the pipe body can be temporarily sealed by using the pipe cap during the sampling process, and therefore, the sampling efficiency can be significantly improved when the nucleic acid detection sampling device is used for nucleic acid mixed sampling; when the cotton head and the rod body are separated by the elastic rubber nozzle, the cotton head is always located in the relatively closed pipe body, so that the sample can be prevented from splashing to the outside, the separation process of the cotton head and the rod body is smooth and controllable, and aerosol is not easy to be produced, and the opportunity of accidentally touching the rod body and other objects or persons is also reduced, so that the secondary transmission of pathogens during the sampling process is avoided; since the elastic rubber nozzle is tightly closed and in a closed state in the natural state, even if the pipe body accidentally falls during the sampling operation, the elastic rubber nozzle can prevent the sample and the fixing liquid in the pipe body from spilling out from the upper port, which greatly improves the safety of the sampling operation. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is a structure diagram of the throat swab.

[0016] Figure 2 It is an exploded structure diagram of the components of the throat swab.

[0017] Figure 3 It is a structure diagram of the throat swab after being partially cut open.

[0018] Figure 4 It is a structure diagram of the sampling pipe.

[0019] Figure 5 It is an exploded structure diagram of the components of the sampling pipe.

[0020] Figure 6 It is an exploded structure diagram of the components of the sampling pipe.

[0021] Figure 7 It is a cooperation diagram of the inner cover and the rubber nozzle.

[0022] Figure 8This is the second schematic diagram showing the fit between the inner cover and the nozzle.

[0023] Figure 9 This is a schematic diagram of the cap structure.

[0024] Figure 10 This is a schematic diagram of the initial state of the sampling tube.

[0025] Figure 11 This is a schematic diagram showing the state of the cotton tip of a throat swab when it is inserted into the insertion hole.

[0026] Figure 12 This is a schematic diagram showing the interaction between the cotton tip and the nozzle as the throat swab moves downwards.

[0027] Figure 13 This is a schematic diagram showing the state of the rod when it is pulled out of the insertion hole.

[0028] Figure 14 This is a schematic diagram showing the interaction between the push ring and the nozzle when the throat swab moves upward.

[0029] Figure 15 This is a schematic diagram showing the coordination of various components when the cap of the sampling tube is screwed on while it is in a sealed state.

[0030] In the diagram, 1. rod body, 2. push ring, 3. cotton head, 4. flat head, 5. tube body, 6. anti-slip texture, 7. tube cap, 8. inner cover, 9. elastic nozzle, 10. eccentric hole, 11. insertion hole, 12. lip, 13. check valve, 14. anti-return, 15. flange ring, 16. eccentric protrusion, 17. sealing gasket. Detailed Implementation

[0031] This invention discloses a nucleic acid detection sampling device, which includes a pharyngeal swab and a sampling tube;

[0032] Among them, see Figures 1-3 As shown, the throat swab includes a slender rod 1, the front end of which is a flat head 4. As the name suggests, the flat head 4 is flat and has a non-circular cross-section. The flat head 4 is provided with a cotton head 3 that wraps around its front end and the outside. A push ring 2 is sleeved on the rod 1. The push ring 2 is located behind the flat head 4. When an external force drives the push ring 2 forward, the push ring 2 will push the cotton head 3 to slide off from the front end of the rod 1.

[0033] Among them, see Figures 4-8,10, the sampling tube is composed of a tube body 5, an inner cover 8 and a tube cap 7; the tube body 5 is an elongated tube, the lower end is closed, the upper end is open, and the upper end is provided with internal threads; the inner cover 8 is provided with external threads on the side wall, the inner cover 8 is arranged in the upper port of the tube body 5 and the two are threadedly connected, rotating the inner cover 8 can rotate it out of the upper port of the tube body 5, an insertion hole 11 is formed in the inner cover 8, the insertion hole 11 can pass through the end of the cotton head 3 of the throat swab, a resilient rubber nozzle 9 is arranged on the lower side of the insertion hole 11 of the inner cover 8, the resilient rubber nozzle 9 is funnel-shaped and the tip is downward, the middle and lower part of the resilient rubber nozzle 9 is divided into a plurality of equally angularly distributed lip petals 12; in the natural state, the lip petals 12 tightly close the lower end of the insertion hole 11, because the resilient rubber nozzle 9 has elasticity, the lip petals 12 can be elastically deformed according to the external force; referring to Figure 11 、 12 , based on the above structure of the throat swab and the sampling tube, when the throat swab is held and the end where the cotton head 3 is located passes through the insertion hole 11 and moves downward, the lip petals 12 will be opened to allow the cotton head 3 and the push ring 2 to enter the tube body 5, thereafter, if the rod body 1 is pulled upward, the push ring 2 is blocked by the lip petals 12 and cannot move upward, the push ring 2 and the cotton head 3 will be separated from the front end of the rod body 1 and left in the tube body 5, and the rod body 1 will be pulled out alone; referring to Figure 13 、 14 , the push ring 2 is blocked by the lip petals 12 and cannot move upward, the push ring 2 and the cotton head 3 will be separated from the front end of the rod body 1 and left in the tube body 5, and the rod body 1 will be pulled out alone; referring to Figure 6 、 9 ,10, the tube cap 7 is provided with a downward extending check column 13 on the top, the lower end of the check column 13 is provided with a check head 14, the check head 14 is conical and the tip is downward; the tube cap 7 and the inner cover 8 are provided with matching matching parts, after the matching parts of the tube cap 7 and the inner cover 8 are matched, the tube cap 7 and the inner cover 8 cannot rotate relative to each other; as shown in Figure 10 , the sampling tube is in an initial state, the tube cap 7 is sleeved on the upper end of the tube body 5 and the two are slidingly sealed, the check head 14 passes through the insertion hole 11 and extends into the resilient rubber nozzle 9, but the lip petals 12 remain closed, in this state, the tube cap 7 can be pulled off the upper end of the tube body 5; as in the initial state, press the tube cap 7 downward, during the process of moving the tube cap 7 to the top of the tube body 5, the check head 14 will open the lip petals 12 and move to the lower side of the resilient rubber nozzle 9, thereafter, the tube cap 7 cannot slide upward based on the cooperation of the check head 14 and the lip petals 12, at the same time, the matching parts between the tube cap 7 and the inner cover 8 reach the matching state, so that the tube cap 7 and the inner cover 8 cannot rotate relative to each other, at this time, the tube cap 7, the inner cover 8 and the tube body 5 reach a stable matching state, that is, the sampling tube reaches a storage state.

[0034] The use method and working principle of the above nucleic acid detection sampling device are as follows:

[0035] According to the existing standard of pharyngeal swab nucleic acid sampling operation, the pharyngeal swab is used to collect the throat secretions of the subject, as shown in Figure 11 、 12 , the cap 7 of the initial state sampling tube is pulled off the tube body 5, the end of the pharyngeal swab with the cotton head 3 is inserted into the insertion hole 11 of the inner cover 8 of the sampling tube, and after feeling a clear jerk, it is indicated that the cotton head 3 and the push ring 2 have passed through the elastic rubber nozzle 9 and entered the tube body 5, and then, as shown in Figure 13 、 14 , the rod body 1 is pulled up, and since the outer diameter of the push ring 2 is certainly larger than the outer diameter of the rod body 1, the push ring 2 will not be able to move upward after being stopped by the lip 12 tightly attached to the outer side of the rod body 1, the push ring 2 and the cotton head 3 will be separated from the front end of the rod body 1, so that the collected specimen remains in the tube body 5 with the cotton head 3 and the push ring 2 and is soaked in the preservative, and the rod body 1 is pulled out separately. The used rod body 1 is stored in the collection container for recycling, after the above operation, the cap 7 is temporarily fitted on the upper end of the tube body 5 to temporarily block the sampling tube, and the cap 7 does not need to be pressed to the bottom so that the cap 7 can be pulled off the upper end of the tube body 5; according to the above method, the samples collected from different subjects are sequentially placed in the tube body 5, and when the number of samples in the tube body 5 reaches the predetermined number required for mixed detection, the cap 7 is fitted on the upper end of the tube body 5 and pressed down to the bottom, so that the top of the cap 7 is stopped by the upper end of the tube body 5, the check valve 14 is opened and moved to the lower side of the elastic rubber nozzle 9, and then the check valve 14 cooperates with the lip 12 to make the cap 7 unable to slide upward, that is, the cap 7 is locked and cannot slide off the upper end of the tube body 5, so that the sampling tube reaches the storage state, and the sampling tube containing the samples is stored in the transport box for laboratory inspection; as shown in Figure 15 , when the sampling tube is in the storage state, the cap 7 and the tube body 5 are in sliding sealing cooperation, the inner cover 8 and the tube body 5 are in threaded cooperation, and the fitting parts of the cap 7 and the inner cover 8 are fitted, based on the cooperation of the above components, the cap 7 and the inner cover 8 can be removed from the upper end of the tube body 5 by screwing the cap 7, so that the upper end of the tube body 5 is opened. Therefore, the sampling tube is suitable for the existing full-automatic capping and sampling system in the subsequent laboratory detection stage.

[0036] In clinical use, the cotton head 3 needs to pass the root of the tongue when the pharyngeal swab is used for sampling, and then wipe the tonsils and the posterior wall of the pharynx on both sides of the subject, and in this process, the force acting on the cotton head 3 in the length direction of the pharyngeal swab is small, so the cotton head 3 will not be separated from the flat head part 4 during the sampling process; at the same time, as shown in Figure 2 、 3 , since the flat head part 4 adopts a non-circular cross-sectional structure design, the cotton head 3 cannot rotate on the flat head part 4, so in the sampling process, the cotton head 3 can be fully contacted with the tissues of the pharynx by twisting the pharyngeal swab, to ensure the sampling effect.

[0037] As shown in Figure 2 In clinical use, after the nucleic acid sampling device completes nucleic acid sampling with the swab, the rod body 1 does not change in structure, and after recovery and centralized processing, it can be used for the production of the swab again, thereby being recycled, which can effectively reduce the use cost of the swab and reduce resource waste and environmental pollution.

[0038] In clinical use, the swab can reduce the overall use cost in a recycling manner, the rod body 1 can be made of high-quality materials, and in addition, the rod body 1 does not need to be pre-broken, so that the overall cotton swab has good strength, the hand feeling is better during sampling operation, and the sampling force and sampling position can be accurately controlled, and the accidental breaking during sampling is effectively avoided, and the operation safety is improved.

[0039] As shown in Figure 11 , 13 In clinical use, after the nucleic acid sampling device completes nucleic acid sampling with the swab, the rod body 1 does not change in structure, and after recovery and centralized processing, it can be used for the production of the swab again, thereby being recycled, which can effectively reduce the use cost of the swab and reduce resource waste and environmental pollution.

[0040] As shown in Figure 12 , 14 In clinical use, when the elastic rubber nozzle 9 separates the cotton head 3 from the rod body 1, the cotton head 3 is always located in the relatively closed tube body 5, so that sample splashing to the outside can be avoided, the separation process of the cotton head 3 and the rod body 1 is smooth and controllable, aerosol is not easy to produce, and the opportunity of the rod body 1 accidentally touching other objects or persons is reduced, thereby avoiding the secondary transmission of pathogens during sampling.

[0041] Further, in the above nucleic acid sampling device, the rod body 1 based on the swab can be recycled, in order to ensure that it has good strength, is convenient to disinfect, has a long service life, and the like, the rod body 1 is made of stainless steel; and the push ring 2 is disposable and is made of plastic.

[0042] Further in the nucleic acid detection sampling device, the elastic rubber nozzle 9 should have good elasticity to ensure that the labial flaps 12 can achieve the desired effect by elastic deformation, so the elastic rubber nozzle 9 should be made of elastomer material, which can be made of rubber or latex material. Figure 7 , 8 As shown in the elastic rubber nozzle 9, the upper end of the flange ring 15 is provided with an integral, the flange ring 15 and the lower end of the inner cover 8 is fixedly connected by adhesive, so as to ensure the cooperation of the elastic rubber nozzle 9 and the insertion hole 11 sealing.

[0043] Further, as shown in Figure 9 , 10 In the nucleic acid detection sampling device, the cap 7 is used to block the upper end of the tube 5. In order to improve the sealing of the cap 7 and the tube 5, a sealing gasket 17 is arranged in the cap 7. The arrangement position and number of the sealing gasket 17 can be set according to the actual situation.

[0044] Further, as shown in Figure 7 , 9 , 10, 15, in the nucleic acid detection sampling device, the cap 7 and the inner cover 8 are provided with a matching part. When the sampling tube reaches the storage state, the matching part can ensure that the cap 7 and the inner cover 8 cannot rotate relative to each other. When the cap 7 is screwed, the inner cover 8 will rotate synchronously to ensure that the cap 7 and the inner cover 8 can be removed from the tube 5 by screwing the cap 7 in the subsequent detection process. Based on the above setting purpose of the matching part, it has various implementation ways, and the following way is preferred:

[0045] The matching part is composed of eccentric hole 10 and eccentric lug 16 which can be inserted and matched. The eccentric hole 10 is arranged on the inner cover 8 and located outside the insertion hole 11. The eccentric lug 16 is located at the lower side of the top of the cap 7. When the eccentric lug 16 is vertically opposite to the eccentric hole 10, the cap 7 can be moved downward to the top of the tube 5, and then the eccentric lug 16 falls into the eccentric hole 10. When implemented, the number of eccentric lug 16 and eccentric hole 10 can be set to one or more pairs according to the actual situation. Based on the above structure of the matching part, on the one hand, after sampling is completed, the cap 7 is placed on the upper end of the tube 5 and moved downward, and the cap 7 is rotated. When the eccentric lug 16 is opposite to the eccentric hole 10, the cap 7 will continue to move downward, and then the eccentric lug 16 falls into the eccentric hole 10, which prevents the cap 7 from rotating relative to the inner cover 8, that is, the above-mentioned necessary function is realized. On the other hand, when the eccentric lug 16 is not opposite to the eccentric hole 10, the cap 7 cannot be moved to the top of the tube 5, thereby reducing the possibility of mistakenly adjusting the sampling tube to the storage state during sampling.

[0046] Further, in the nucleic acid detection sampling device, the preservative liquid for soaking the sample can be added into the tube 5 temporarily before sampling, or can be added into the tube 5 in advance when the sampling tube is produced, i.e. the sampling tube is sealed with the preservative liquid in the tube 5 in the initial state. As shown in Figure 10 Although the cap 7 is not locked in the initial state of the sampling tube, i.e. the cap 7 can be pulled off from the upper end of the tube 5, the cap 7 is not easily driven to move upward by external force in the case of non-human operation, so the cap 7 can be sealed with the tube 5 to prevent the preservative liquid from flowing out, and at the same time, the sampling tube is stored in the packaging bag before use, and the outer package can be used to bind the sampling tube in the initial state to prevent the cap 7 from slipping off from the upper end of the tube 5.

[0047] Further, as shown in Figure 4 In the nucleic acid detection sampling device, the outer side wall of the cap 7 is provided with anti-skid lines 6 to facilitate manual rotation.

[0048] Further, as shown in Figure 9 In the nucleic acid detection sampling device, the cap 7, the check column 13 and the check head 14 are integrated and made of plastic.

Claims

1. A nucleic acid detection sampling device comprising a throat swab and a sampling tube, characterized in that: The pharyngeal swab comprises a rod body, a flat head part with a non-circular cross section at the front end of the rod body, a cotton head provided on the flat head part to wrap the front end and the outside of the flat head part, and a push ring provided on the rod body and located at the rear side of the flat head part; an external force drives the push ring to move forward, and the push ring pushes the cotton head to slide off the front end of the rod body; the sampling tube comprises a tube body, an inner cover and a tube cap; the lower end of the tube body is closed and the upper end is open; the inner cover is arranged in the upper end port of the tube body and is threadedly connected with the tube body; an insertion hole is formed in the inner cover and is used for allowing the cotton head end of the pharyngeal swab to pass through; a funnel-shaped elastic rubber nozzle is arranged at the lower side of the insertion hole and has a downward pointed tip; the middle and lower parts of the elastic rubber nozzle are divided into a plurality of equiangularly distributed lip petals; in a natural state, the lip petals are tightly buckled to close the lower end of the insertion hole; when the pharyngeal swab passes through the insertion hole and moves downward, the lip petals are opened to allow the cotton head and the push ring to enter the tube body; thereafter, if the rod body is pulled upward, the push ring is blocked by the lip petals and cannot move upward, the push ring and the cotton head are separated from the front end of the rod body and remain in the tube body, and the rod body is pulled out alone; the tube cap is provided with a downward extending check column at the top, the lower end of the check column is provided with a tapered check head with a downward pointed tip, and a matching matching part is arranged between the tube cap and the inner cover; in an initial state, the tube cap is sleeved on the outer part of the upper end of the tube body and is slidingly and sealingly connected with the tube body, the check head passes through the insertion hole and extends into the elastic rubber nozzle, and the lip petals remain in the buckled state; during the process of driving the tube cap to move downward to abut against the tube body, the check head opens the lip petals and moves to the lower side of the elastic rubber nozzle, the tube cap cannot slide upward based on the cooperation of the check head and the lip petals, the matching part between the tube cap and the inner cover is matched to prevent the tube cap and the inner cover from rotating relative to each other, and the tube cap can be unscrewed to be separated from the inner cover; the matching part comprises an eccentric hole and an eccentric protrusion which are inserted and matched, the eccentric hole is arranged on the inner cover and located at the outside of the insertion hole, and the eccentric protrusion is located at the lower side of the top of the tube cap; only when the eccentric protrusion and the eccentric hole are vertically opposite, the tube cap can move downward to abut against the tube body, and thereafter the eccentric protrusion falls into the eccentric hole.

2. The nucleic acid testing sampling device of claim 1, wherein: The rod body is made of stainless steel; and the push ring is made of plastic.

3. The nucleic acid detection sampling device of claim 1, wherein: The upper end of the elastic rubber nozzle is provided with a flange ring which is integrally connected with the elastic rubber nozzle; and the flange ring is fixedly connected with the lower end surface of the inner cover by adhesion.

4. The nucleic acid testing sampling device of claim 1, wherein: The tube cap is provided with a sealing ring.

5. The nucleic acid detection sampling device of claim 1, wherein: The sampling tube is provided with a preservation liquid in the tube body in an initial state.

6. The nucleic acid detection sampling device of claim 1, wherein: The outer wall of the tube cap is provided with anti-skid lines.

7. The nucleic acid testing sampling device of claim 1, wherein: The tube cap, the check column and the check head are integrally formed and made of plastic.

Images