Pipette cylinder and pipette

Abstract

The present invention relates to a pipette cylinder and a pipette. The pipette cylinder includes: a cylinder body having a first accommodation cavity inside, and the cylinder body is provided with a first opening and a second opening that communicate the first accommodation cavity with the external environment; a hollow guide rod, at least part of which is located in the first accommodation cavity, and the hollow guide rod has a second accommodation cavity; the hollow guide rod has a third opening that communicates the second accommodation cavity with the first accommodation cavity and a fourth opening that communicates the second accommodation cavity; the outer side wall of the end of the hollow guide rod provided with the fourth opening is hermetically docked with the side wall of the second opening; the hollow guide rod is movable to switch between a closed state and an open state; the hollow guide rod has a closed portion located in the first accommodation cavity; when the hollow guide rod is in the closed state, the closed portion of the hollow guide rod closes the first opening; when the hollow guide rod is in the open state, the closed portion of the hollow guide rod disengages from the first opening. The pipette cylinder and the pipette provided by the present invention make the liquid suction port of the pipette cylinder easier to seal and simplify the structure.

Description

Technical Field

[0001] The present invention relates to the field of chemical experimental instruments, and particularly to a pipette cylinder and a pipette. Background Art

[0002] A pipette, also known as a pipetting gun, is a device used for quantitatively transferring liquids. When conducting research in analytical testing, a pipette is generally used to transfer small or trace amounts of liquid. Pipettes can be classified into gas piston pipettes and external piston pipettes according to their principles. Gas piston pipettes are mainly used for standard pipetting, and external piston pipettes are mainly used for handling special liquids such as volatile, corrosive, and viscous liquids. Currently, the pipette cylinder of an external piston pipette has problems such as poor sealing performance of the liquid suction port or a complex sealing structure. Summary of the Invention

[0003] In view of this, embodiments of the present application provide a pipette cylinder and a pipette to solve at least one problem in the background art.

[0004] To achieve the above object, the technical solution of the present application is implemented as follows:

[0005] In a first aspect, an embodiment of the present application provides a pipette cylinder, including:

[0006] A cylinder body having a first accommodation cavity therein, and the cylinder body is provided with a first opening and a second opening that communicate the first accommodation cavity with the external environment;

[0007] A hollow guide rod, at least part of which is located in the first accommodation cavity, and the hollow guide rod has a second accommodation cavity; the hollow guide rod has a third opening that communicates the second accommodation cavity with the first accommodation cavity and a fourth opening that communicates the second accommodation cavity; the outer side wall of the end of the hollow guide rod provided with the fourth opening is hermetically docked with the side wall of the second opening; the hollow guide rod can move to switch between a closed state and an open state; the hollow guide rod has a closed portion located in the first accommodation cavity; when the hollow guide rod is in the closed state, the closed portion of the hollow guide rod closes the first opening; when the hollow guide rod is in the open state, the closed portion of the hollow guide rod disengages from the first opening.

[0008] Optionally, the first opening and the second opening are arranged in opposite directions, and the arrangement direction of the first opening and the second opening is a first direction; the cylinder body has a guiding structure for guiding the relative movement of the hollow guide rod along the first direction with respect to the cylinder body, so that the hollow guide rod switches between the closed state and the open state.

[0009] Optionally, the pipette cylinder further includes a first driving component for driving the hollow guide rod to move.

[0010] Optionally, a magnetic member cooperating with the first driving assembly is provided on the hollow guide rod; the first driving assembly includes:

[0011] An electromagnet, which is matched with the magnetic member to attract the magnetic member when powered on, and drive the hollow guide rod to switch from the closed state to the open state; a reset member, which is used to push the hollow guide rod to switch from the open state to the closed state when the electromagnet is powered off.

[0012] Optionally, the pipette cylinder further includes a partition, which divides the first accommodating cavity into a first sub-cavity and a second sub-cavity in a first direction; the first sub-cavity communicates with the first opening, and the second sub-cavity communicates with the second opening; the hollow guide rod passes through the partition, the third opening of the hollow guide rod is located in the first sub-cavity, and the fourth opening is located in the second sub-cavity; both the electromagnet and the reset member are installed in the second sub-cavity.

[0013] Optionally, the guiding structure is a through hole opened on the partition, and the diameter of the through hole is greater than a preset value of the diameter of the hollow guide rod.

[0014] Optionally, the cylinder body includes:

[0015] A first cylinder body, which has the first sub-cavity, and the end plate at one end of the first cylinder body away from the first opening in the first direction is the partition;

[0016] A second cylinder body, which is fixed to one end of the first cylinder body having the partition; one end of the reset member abuts against the inner wall of the end of the second cylinder body away from the first cylinder body, and the other end abuts against the hollow guide rod;

[0017] A third cylinder body, which is fixed to the end of the second cylinder body away from the first cylinder body, and the electromagnet is accommodated in the third cylinder body; the inner cavities of the third cylinder body and the second cylinder body communicate with each other to form the second sub-cavity.

[0018] In a second aspect, an embodiment of the present application provides a pipette, including any one of the above pipette cylinders.

[0019] Optionally, the pipette further includes:

[0020] A gas operating mechanism, which has a gas transmission channel for sealingly docking the fourth opening of the second accommodating cavity; the gas operating mechanism sucks or discharges gas through the gas transmission channel, so that the first opening of the pipette cylinder sucks or discharges a preset volume of liquid.

[0021] Optionally, the gas operating mechanism includes a syringe barrel, and the syringe barrel includes:

[0022] The air cylinder body has a third accommodation cavity; one end of the air cylinder body is provided with a fifth opening communicating with the third accommodation cavity, and the fifth opening is hermetically docked with the air delivery channel;

[0023] A piston is located in the third accommodation cavity and can move relative to the air cylinder body within the third accommodation cavity.

[0024] Optionally, the gas operating mechanism further includes:

[0025] A second driving assembly for driving the movement of the piston relative to the air cylinder body.

[0026] Optionally, the gas operating mechanism further includes:

[0027] A movement linkage member for realizing the linkage between the piston and the second driving assembly, and both the air cylinder and the second driving assembly are located on the same side of the movement linkage member.

[0028] Optionally, the air delivery channel is a gas conduit, and one end of the gas conduit hermetically docked to the second opening includes a nozzle matching the second opening.

[0029] Optionally, the gas conduit is arranged in a U shape, and both the fifth opening and the second opening are at one end of the U-shaped opening of the gas conduit.

[0030] Optionally, the pipette further includes a manipulator matching the pipette cylinder to drive the pipette cylinder to move to a position docked with the air delivery channel.

[0031] A pipette cylinder and a pipette provided by an embodiment of the present application, the pipette cylinder includes a cylinder body and a hollow guide rod. Among them, the cylinder body has a first accommodation cavity inside, and the cylinder body is provided with a first opening and a second opening communicating the first accommodation cavity with the external environment; the hollow guide rod has a third opening communicating the second accommodation cavity with the first accommodation cavity and a fourth opening communicating the second accommodation cavity; the outer side wall of one end of the hollow guide rod provided with the fourth opening is hermetically docked with the side wall of the second opening; the hollow guide rod is movable to switch between a closed state and an open state; the hollow guide rod has a closed portion located in the first accommodation cavity; when the hollow guide rod is in the closed state, the closed portion of the hollow guide rod closes the first opening; when the hollow guide rod is in the open state, the closed portion of the hollow guide rod disengages from the first opening. In this way, the pipette cylinder of the embodiment of the present application can realize the sealing of the first opening, that is, the liquid suction port, by the switching of the hollow guide rod between the first state and the second state, making the liquid suction port of the pipette cylinder easier to seal and simplifying the structure. Thus, the pipette cylinder and the pipette provided by the embodiment of the present application make the liquid suction port of the pipette cylinder easier to seal and simplify the structure.

[0032] Additional aspects and advantages of the present application will be given in part in the following description, become apparent in part from the following description, or be learned through the practice of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The schematic embodiments and descriptions thereof of the present application are used to explain the present application and do not constitute an improper limitation to the present application. In the drawings:

[0034] Figure 1 Schematic diagram of the pipette provided by the embodiment of the present application;

[0035] Figure 2 Cross-sectional schematic view of the pipette cylinder in the pipette provided by the embodiment of the present application Figure 1 (The hollow guide rod is in a closed state);

[0036] Figure 3 Cross-sectional schematic view of the pipette cylinder in the pipette provided by the embodiment of the present application Figure 2 (The hollow guide rod is in an open state);

[0037] Figure 4 Schematic diagram of the working state of the gas operating mechanism in the pipette provided by the embodiment of the present application Figure 1 (Outputting gas);

[0038] Figure 5 Schematic diagram of the working state of the gas operating mechanism in the pipette provided by the embodiment of the present application Figure 2 (Drawing in gas);

[0039] Figure 6 Top view of the pipette provided by the embodiment of the present application (the pipette cylinder is not shown);

[0040] Figure 7 Schematic diagram of the gas flow in the pipette provided by the embodiment of the present application;

[0041] Figure 8 Schematic diagram of the pipette cylinder installed on the gas conduit in the pipette provided by the embodiment of the present application;

[0042] Figure 9 Schematic diagram of disassembling the pipette cylinder in the pipette provided by the embodiment of the present application.

[0043] Description of the reference numerals:

[0044] 10. Pipette cylinder; 11. First opening; 12. Second opening; 131. First cylinder body; 132. Second cylinder body; 133. Third cylinder body; 134. Partition board; 14. Hollow guide rod; 141. Third opening; 142. Fourth opening; 151. Electromagnet; 152. Reset part; 161. First sealing ring; 162. Second sealing ring; 163. Third sealing ring; 164. Fourth sealing ring; 20. Gas operating mechanism; 21. Air cylinder; 211. Air cylinder body; 212. Fifth opening; 213. Piston; 22. Second driving component; 23. Frame plate; 24. Movement linkage; 25. Gas conduit; 251. Gas nozzle; 31. Demounting wrench; 32. Third driving component. Detailed implementation manners

[0045] The exemplary embodiments disclosed in the present application will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present application are shown in the drawings, it should be understood that the present application can be implemented in various forms and should not be limited by the specific implementation manners set forth herein. On the contrary, these embodiments are provided so that the present application can be more thoroughly understood and the scope of the present application disclosed can be fully communicated to those skilled in the art.

[0046] In the following description, a large number of specific details are given to provide a more thorough understanding of the present application. However, it is obvious to those skilled in the art that the present application can be implemented without one or more of these details. In other examples, in order to avoid confusion with the present application, some technical features well known to those skilled in the art are not described; that is, not all features of the actual embodiments are described here, and the well-known functions and structures are not described in detail.

[0047] In the various specific technical features described in the specific embodiments, they can be combined in any suitable manner without contradiction. For example, different embodiments and technical solutions can be formed by combining different specific technical features. To avoid unnecessary repetition, various possible combination methods of the various specific technical features in the present invention will not be described separately.

[0048] In the following description, the terms "first / second / ..." involved are only used to distinguish different objects and do not indicate that there are the same or related connections between the objects. It should be understood that unless otherwise specified, the orientation descriptions "above", "below", "outside", and "inside" involved are the orientations in the normal use state, and the "left" and "right" directions represent the left and right directions shown in the specific corresponding schematic diagrams.

[0049] It should be noted that the terms "comprise", "include" or any other variants thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements not only includes those elements but also other elements not expressly listed, or elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising a..." does not exclude the presence of additional identical elements in the process, method, article or device comprising that element.

[0050] Spatial relationship terms such as "under", "below", "lower", "beneath", "above", "upper", etc. are used herein for convenience in describing the relationship of one element or feature shown in the figures to other elements or features. It should be understood that, in addition to the orientation shown in the figures, spatial relationship terms are intended to include different orientations of the device in use and operation. For example, if the device in the figures is flipped, then an element or feature described as "under" or "beneath" or "below" other elements will be oriented "above" the other elements or features. Thus, the exemplary terms "under" and "below" can include both an upper and a lower orientation. The device may be otherwise oriented (rotated 90 degrees or other orientations) and the spatial descriptors used herein are to be interpreted accordingly.

[0051] The purpose of the terms used herein is only to describe specific embodiments and is not a limitation of the present application. As used herein, the singular forms "a", "an" and "the" are also intended to include the plural forms unless the context clearly dictates otherwise. It should also be understood that the terms "consisting of" and / or "including", when used in this specification, determine the presence of the stated features, integers, steps, operations, elements and / or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or groups. As used herein, the term "and / or" includes any and all combinations of the related listed items.

[0052] To fully understand the present application, detailed steps and structures will be presented in the following description to illustrate the technical solutions of the present application. The preferred embodiments of the present application are described in detail below. However, in addition to these detailed descriptions, the present application may have other embodiments.

[0053] To solve the technical problems in the prior art, an embodiment of the present application provides a pipette, as Figure 1 shown, the pipette includes a pipette barrel 10. As Figure 2 and Figure 3As shown, the pipetting cylinder 10 includes a cylinder body and a hollow guide rod 14. The interior of the cylinder body has a first accommodation cavity. The cylinder body is provided with a first opening 11 and a second opening 12 that communicate the first accommodation cavity with the external environment. Figure 1 The figure shows the normal working state of the pipette according to the embodiment of the present application, that is, the pipetting cylinder 10 is placed vertically, which is also convenient for the smooth discharge of the liquid.

[0054] As Figure 2 and Figure 3 As shown, at least a part of the hollow guide rod 14 is located in the first accommodation cavity. The hollow guide rod 14 has a second accommodation cavity. The hollow guide rod 14 has a third opening 141 that communicates the second accommodation cavity with the first accommodation cavity and a fourth opening 142 that communicates the second accommodation cavity. The outer side wall of the end of the hollow guide rod 14 provided with the fourth opening 142 is hermetically docked with the side wall of the second opening 12. The hollow guide rod 14 can move to switch between a closed state and an open state. The hollow guide rod 14 has a closed part located in the first accommodation cavity. When the hollow guide rod 14 is in the closed state, the closed part of the hollow guide rod 14 closes the first opening 11. When the hollow guide rod 14 is in the open state, the closed part of the hollow guide rod 14 disengages from the first opening 11.

[0055] In the present application, the first accommodation cavity is mainly used to accommodate the liquid to be transferred, and the second accommodation cavity can be used as a channel for gas to enter and exit the first accommodation cavity. The liquid in the present application is generally used in chemical experiments, and the gas can be the air in the atmosphere. In this way, the pipetting cylinder according to the embodiment of the present application can realize the sealing of the first opening 11, that is, the liquid suction port, by switching the hollow guide rod 14 between the first state and the second state; making the liquid suction port of the pipetting cylinder easier to seal and simplifying the structure. In addition, since the cross-sectional area of the second accommodation cavity of the hollow guide rod 14 can be limited to be much smaller than the cross-sectional area of the cylinder body, according to the principle of fluid mechanics, the flow rate of the gas will increase, and the liquid suction or drainage speed of the pipetting cylinder can be improved.

[0056] In the present application, the closed part can be a shaft part that matches the size of the first opening 11. For example, if the first opening 11 is a circular hole, then the closed part can be a cylinder. In order for the hollow guide rod 14 to switch between the first state and the second state, the size of the first opening 11 is larger than the size of the closed part, that is, there is a gap between the two. If the first opening 11 is a circular hole, then the diameter of the first opening 11 is larger than the diameter of the closed part. In order to achieve the sealing of the first opening 11, the gap can be relatively small, for example, the gap is less than or equal to 0.2 mm, and a sealing ring is provided. To distinguish it from others, the sealing ring here is called the first sealing ring 161, and so on. In some embodiments, for the convenience of processing, the closed part and the other parts of the hollow guide rod 14 can be integrally formed.

[0057] As Figure 2 and Figure 3 shown, the first opening 11 and the second opening 12 are arranged in opposite directions, and the arrangement direction of the first opening 11 and the second opening 12 is the first direction; a guiding structure for guiding the relative movement of the hollow guide rod 14 along the first direction with respect to the cylinder body is provided in the first accommodating cavity, so that the hollow guide rod 14 can be switched between the closed state and the open state. That is, in addition to allowing gas to enter and exit the first accommodating cavity, the hollow guide rod 14 can also play a role in opening or closing the first opening 11. The guiding structure can guide the hollow guide rod 14 to move along a preset trajectory, making the movement trajectory of the hollow guide rod 14 more precise; the preset trajectory can be a trajectory for opening or closing the first opening 11.

[0058] In some embodiments, as Figure 2 and Figure 3 shown, the pipette cylinder 10 may further include a first driving assembly for driving the hollow guide rod 14 to move along the first direction. The first driving assembly can be installed on the cylinder body and correspond to the position of the hollow guide rod 14. Through the first driving assembly, the movement of the hollow guide rod 14 can be coordinated with the liquid transfer of the cylinder body. For example, after the liquid sucked into the first accommodating cavity reaches a preset volume, the first driving assembly can drive the hollow guide rod 14 to move to close the liquid inlet and outlet, making the volume of the liquid extracted into the first accommodating cavity more precise.

[0059] In some embodiments, as Figure 2 and Figure 3 shown, a magnetic attracting member for cooperating with the first driving assembly is provided on the hollow guide rod 14; the first driving assembly may include an electromagnet 151 and a reset member 152. Among them:

[0060] The electromagnet 151 is matched with the magnetic attracting member to attract the magnetic attracting member in the energized state, and drive the hollow guide rod 14 to switch from the closed state to the open state. In some embodiments, the electromagnet 151 may be spaced apart from one end of the hollow guide rod 14 away from the first opening 11, for example, disposed at a preset distance from one end away from the first opening 11, and the magnetic attracting member is fixed to one end of the hollow guide rod 14 away from the first opening 11. In this way, it is convenient for the cooperation between the electromagnet 151 and the magnetic attracting member; the preset distance can be a distance at which the magnetic field of the electromagnet can generate an attracting effect on the magnetic attracting member. In some embodiments, the magnetic attracting member may be made of a ferromagnetic material. The ferromagnetic material in the present application refers to a material that can be magnetized, such as iron, steel, nickel, etc.

[0061] In this embodiment, as Figure 2 and Figure 3As shown, the end away from the first opening 11 is the upper end of the hollow guide rod 14 in the vertical direction, and the magnetic attraction member can be fixed to the upper end of the hollow guide rod 14. The electromagnet 151 is disposed at a preset distance from the upper end of the hollow guide rod 14. It can be that when not energized, the electromagnet 151 is spaced from the upper end of the hollow guide rod 14 by a first preset distance, and when energized, the electromagnet 151 can be in contact with the upper end of the hollow guide rod 14 or spaced from it by a second preset distance, and the second preset distance is less than the first preset distance. Figure 2 As shown, this is the case where the electromagnet 151 is not energized. Figure 3 As shown, this is the case where the electromagnet 151 is energized. Driving the movement of the hollow guide rod 14 by the electromagnet has the advantages of simple structure, small volume and low energy consumption.

[0062] As Figure 2 and Figure 3 As shown, the reset member 152 is used to push the hollow guide rod 14 to switch from the open state to the closed state when the electromagnet 151 is de-energized. That is, it pushes the closing part of the hollow guide rod 14 into the first opening 11 to close the first opening 11. In some embodiments, the reset member 152 can be an elastic member. When one end of the hollow guide rod 14 is pulled out of the first opening 11 under the magnetic attraction of the electromagnet 151, the elastic member is compressed and stores energy, and generates a return force. However, since the return force is less than the magnetic attraction of the electromagnet 151, it cannot prevent the movement of the hollow guide rod 14. When the electromagnet 151 is de-energized, the magnetic attraction of the electromagnet 151 disappears, and the return force of the elastic member takes effect, which can push the movement of the hollow guide rod 14. In some embodiments, the reset member 152 can be an elastic member such as a compression spring, so that the structure is simpler. It can be understood that the reset member 152 can also be other structures. For example, it can be reset by another electromagnetic component with an opposite magnetic attraction, or it can be reset by other power components such as a cylinder or a linear motor.

[0063] In some embodiments, as Figure 2 and Figure 3As shown, the pipetting cylinder 10 may further include a partition plate 134, which divides the first accommodating cavity into a first sub-cavity and a second sub-cavity in a first direction; the first sub-cavity communicates with the first opening 11, and the second sub-cavity communicates with the second opening 12; the hollow guide rod 14 passes through the partition plate 134, and the third opening 141 of the hollow guide rod 14 is located in the first sub-cavity, and the fourth opening 142 is located in the second sub-cavity; the electromagnet 151 and the reset member 152 are both installed in the second sub-cavity. In this way, the first sub-cavity is used to accommodate the liquid, and the second sub-cavity is used to install the electromagnet 151 and the reset member 152, and the two do not interfere with each other. Components such as the electromagnet 151 and the reset member 152 will not be affected by the transferred liquid, because the transferred liquid may have characteristics such as corrosiveness. Therefore, in addition to the cylinder body, the hollow guide rod 14 and the sealing rings inside the pipetting cylinder 10 need to be made of anti-corrosion materials such as polytetrafluoroethylene. Other parts of the pipette can be made of common materials such as glass, plastic, and metal because they are out of the possibility of contacting the liquid, without considering the anti-corrosion performance, which reduces the manufacturing cost.

[0064] In some embodiments, as Figure 2 and Figure 3 shown, the guiding structure may be a through hole formed in the partition plate 134, and the diameter of the through hole is greater than a preset value of the diameter of the hollow guide rod 14, that is, there is a gap between the two, so that the movement of the hollow guide rod 14 during the process of switching from the closed state to the open state is smoother. For the sealing of the first accommodating cavity, the gap can be relatively small, for example, the gap is less than or equal to 0.05 mm, and a second sealing ring 162 is provided. In this application, the second sealing ring 162 is provided to prevent the liquid in the first accommodating cavity from overflowing from the joint of the guiding structure and the hollow guide rod, and can also prevent gas from entering and leaving the first accommodating cavity through the second accommodating cavity of the hollow guide rod 14, making the volume of the transferred liquid more accurate.

[0065] Exemplarily, the fitting gap between the guiding structure and the hollow guide rod 14 is adapted to the fitting gap between the closed part of the hollow guide rod 14 and the first opening 11. That is, the fitting gap between the guiding structure and the hollow guide rod 14 does not affect the sealing of the first opening 11.

[0066] In some embodiments, as Figure 2 and Figure 3 shown, the cylinder body may include a first cylinder body 131, a second cylinder body 132, and a third cylinder body 133. Among them:

[0067] The first cylinder body 131 has the first sub-cavity, and the end plate at the end of the first cylinder body 131 away from the first opening 11 in the first direction is the partition plate 134. That is, the first cylinder body 131 encloses the first sub-cavity, and the end of the first cylinder body 131 away from the first opening 11 in the first direction is the upper end in the vertical direction, that is, the end plate at the upper end of the first cylinder body 131 is the above-mentioned partition plate 134. In some embodiments, the first cylinder body 131 may include a barrel body and a barrel cover combined with each other. Among them, the end plate at the upper end of the barrel cover is the partition plate 134. Since the opening sizes at the upper and lower ends of the first cylinder body 131 are much smaller than the cross-sectional size of the first accommodating cavity, by setting the first cylinder body 131 to include a barrel body and a barrel cover, and processing and assembling them separately, it is beneficial to reduce the processing difficulty and manufacturing cost.

[0068] The second cylinder body 132 is fixed to the end of the first cylinder body 131 having the partition plate 134, that is, the second cylinder body 132 is fixed to the upper end of the first cylinder body 131. The inner wall of the end of the second cylinder body 132 away from the first cylinder body 131 abuts against the reset member 152; that is, one end of the reset member 152 abuts against the inner wall of the end of the second cylinder body 132, and the other end abuts against the hollow guide rod 14. In this way, when the hollow guide rod 14 moves upward, the second cylinder body 132 remains stationary, the upper end of the reset member 152 is fixed, and the lower end moves upward with the upward movement of the hollow guide rod 14. Therefore, the reset member 152 is compressed and stores energy. In some embodiments, the hollow guide rod 14 may include a step that abuts against the reset member 152. Through the second cylinder body, the upper end of the reset member 152 can be fixed by abutting against the inner wall of the upper end of the second cylinder body, simplifying the fixing structure.

[0069] The third cylinder body 133 is fixed to the end of the second cylinder body 132 away from the first cylinder body 131, and the electromagnet 151 is accommodated in the third cylinder body 133; the inner cavities of the third cylinder body 133 and the second cylinder body 132 communicate with each other to form the second sub-cavity. Exemplarily, through holes are provided in the top wall of the second cylinder body 132 and the bottom wall of the third cylinder body 133, so that the inner cavities of the second cylinder body 132 and the third cylinder body 133 communicate with each other to form the second sub-cavity. Exemplarily, the electromagnet 151 accommodated in the third cylinder body 133 is provided with a through hole for gas circulation in the middle, so that the fourth opening 142 of the hollow guide rod 14 can communicate with the second opening 12. Exemplarily, the inner cavity of the second sub-cavity is relatively large, while the opening of the second sub-cavity communicating with the outside or the first sub-cavity is relatively small. By forming the second sub-cavity by combining the second cylinder body 132 and the third cylinder body 133, it is beneficial to reduce the processing difficulty and manufacturing cost. For the sealing of the second sub-cavity, a third sealing ring 163 is provided at the installation place of the second cylinder body 132 and the third cylinder body 133.

[0070] In some embodiments, the cross-sections of the first cylinder 131, the second cylinder 132, and the third cylinder 133 can all be circular, and the cross-section of the hollow guide rod 14 can also be circular. In this way, it can be processed by processing equipment such as lathes that are good at processing rotating bodies, and higher processing efficiency and lower costs can be obtained. In some embodiments, for the stability of the structure and the convenience of processing, the axis of the hollow guide rod 14 is consistent with the axes of the first cylinder 131, the second cylinder 132, and the third cylinder 133. Exemplarily, for a relatively large magnetic suction force, the cross-section of the electromagnet 151 can also be circular, and the axis of the electromagnet 151 is consistent with the axis of the hollow guide rod 14. In some embodiments, the circular electromagnet 151 can be provided with a through hole concentric with the outer circular surface of the electromagnet 151, so that the fourth opening 142 of the hollow guide rod 14 can communicate with the second opening 12, and the structure of the electromagnet 151 is more stable. Moreover, since the provided through hole is concentric with the outer circular surface of the electromagnet, it is beneficial to the processing by processing equipment such as lathes that use the axis of the part as the positioning reference, and higher processing efficiency and lower costs can be obtained.

[0071] In this application, the cylinder includes internal structures such as a partition 134 and the top wall of the second cylinder, and the opening sizes of the first opening 11 and the second opening 12 are relatively small. Therefore, whether it is cutting processing or casting processing, there are great difficulties. Therefore, decomposing the cylinder into the first cylinder 131, the second cylinder 132, and the third cylinder 133 is beneficial to simplifying the processing difficulty and reducing the manufacturing cost.

[0072] In some embodiments, the pipette further includes a gas operation mechanism 20. As Figure 1 shown, the gas operation mechanism 20 has a gas transmission channel that is hermetically docked to the fourth opening 142 of the second accommodation cavity; the gas operation mechanism 20 sucks or discharges gas through the gas transmission channel, so that the first opening 11 of the pipette cylinder 10 sucks or discharges a preset volume of liquid.

[0073] In this application, the preset volume of liquid is the volume of the liquid to be transferred. In order to make the volume of the transferred liquid more accurate, it can be achieved by controlling the gas operation mechanism 20 to suck or discharge a preset volume of gas. In this application, the preset volume of gas and the preset volume of liquid may be the same or slightly different. However, for a pipette with a determined structure and size, the corresponding relationship between the two is relatively stable and is a positive correlation. Therefore, the volume of the transferred liquid can be accurately controlled by controlling the volume of the gas.

[0074] In some embodiments, the gas operating mechanism 20 can extract or output gas according to a control instruction. It is an automated mechanism that does not require manual operation, enabling the volume of the transferred liquid to be controlled more precisely. Different precision-level devices can be selected as needed to adapt to pipetting operations with different precision requirements. Additionally, the automation of the gas operating mechanism 20 is generally not limited by the strength of human hands, enabling the transfer of large-volume liquids and multiple transfers, which can improve the efficiency of liquid transfer.

[0075] In this application, the control instruction can be issued by a control component (not shown in the figure). The control component sends the control instruction to the gas operating mechanism 20 based on the volume information of the liquid to be aspirated or discharged in the pipette cylinder 10 received. The control component is electrically connected to the gas operating mechanism 20. In this application, the liquid volume information is issued by the user. The user can directly input it through a key or can be linked with other devices and input by other devices. If it is batch processing, it can also be input through a program, etc. In some embodiments, the liquid volume information can also be directly input by the user through voice. The control component can be provided with a corresponding voice recognition component. In this way, inputting the liquid volume information is more convenient. And voice input can also be input remotely, which is suitable for the transfer of some toxic liquids.

[0076] In some embodiments, as Figure 1 shown, the gas operating mechanism 20 and the pipette cylinder 10 can be detachably connected. In this way, the pipette of this embodiment can perform long-distance liquid sealed transfer. Also, it is convenient to clean the pipette cylinder 10 because the transferred liquid is mostly for chemical experiments and needs to be cleaned thoroughly after each transfer. It can be understood that when long-distance liquid transfer is not required, the gas operating mechanism 20 and the pipette cylinder 10 can also be fixedly connected.

[0077] In some embodiments, as Figure 4 and Figure 5 shown, the gas operating mechanism 20 can include a cylinder 21, and the cylinder 21 includes a cylinder body 211 and a piston 213. Among them,

[0078] the cylinder body 211 has a third accommodation cavity; one end of the cylinder body 211 is provided with a fifth opening 212 communicating with the third accommodation cavity, and the fifth opening 212 is hermetically docked with the gas transmission channel, see Figure 7 .

[0079] The piston 213 is located in the third accommodation cavity and can move relative to the cylinder body 211 in the third accommodation cavity.

[0080] In some embodiments, the movement of the piston 213 relative to the cylinder body 211 may be a linear movement. Through the linear movement of the piston 213, the cylinder 21 can extract gas from the pipetting cylinder 10 or output gas to the pipetting cylinder 10. The principle of the cylinder 21 is somewhat similar to that of an ordinary inflator. However, the nozzle 251 of an ordinary inflator only inflates and does not extract gas. The cylinder 21 of this embodiment not only inflates but also extracts gas, and has better airtightness, which is beneficial to extracting or outputting an accurate volume of gas.

[0081] In some embodiments, the gas operating mechanism 20 further includes a second driving component 22. The second driving component 22 is used to drive the movement of the piston 213 relative to the cylinder body 211. Exemplarily, the gas operating mechanism 20 extracts gas from the pipetting cylinder 10 or outputs gas to the pipetting cylinder 10, and causes the first opening 11 of the pipetting cylinder 10 to suck or discharge a preset volume of liquid. Its accuracy is mainly achieved by the second driving component 22. The second driving component 22 can calculate the volume of gas that needs to be extracted or output according to the volume of liquid to be transferred, so as to determine the moving distance of the second driving component 22 driving the piston 213. Exemplarily, to determine the moving distance of the piston 213, it can be calculated and determined through the inner diameter of the cylinder body 211 or the outer diameter of the piston 213. In some embodiments, the second driving component 22 can select a device that can accurately control the moving distance of the piston 213. For example, a stepper motor or a servo motor, etc.

[0082] In some embodiments, as Figure 6 and Figure 7 shown, the gas operating mechanism 20 may further include a motion linkage 24. The motion linkage 24 is used to realize the linkage between the piston 213 and the second driving component 22. Both the cylinder 21 and the second driving component 22 are located on the same side of the motion linkage. From Figure 4 and Figure 5 it can be seen that the cylinder 21 and the second driving component 22 are arranged in a U shape. In this way, the height of the gas operating mechanism 20 in the vertical direction is reduced, which is convenient for the integration of automated equipment.

[0083] In some embodiments, the gas operating mechanism 20 may further include a frame plate 23. The gas cylinder 21 and the second drive assembly 22 are both fixed to the frame plate 23; illustratively, on the one hand, the frame plate 23 is used to fix the relative positions of the gas cylinder 21 and the second drive assembly 22, so that the second drive assembly 22 can be better transmitted. On the other hand, the frame plate 23 can also be fixed to the ground, wall or workbench to fix the pipette or the gas operating mechanism 20 in the pipette, which is conducive to the stability of the pipetting process. It can be understood that the shape of the frame plate 23 may not be plate-shaped in other embodiments of the present application, as long as it can fix the gas cylinder 21 and the second drive assembly 22.

[0084] like Figure 4 and Figure 5 As shown, the second drive assembly 22 includes a power output shaft that drives the piston 213 to move, and the motion trajectory of the power output shaft is a straight line. That is, the motion trajectory of the power output shaft of the second drive assembly 22 is the same as the trajectory of the piston 213 of the cylinder 21, both of which are straight lines. This is conducive to simplifying the structure of the mechanism, reducing energy loss in motion trajectory conversion, and improving the efficiency of the mechanism. In some embodiments, the second drive assembly 22 can be a fixed-axis screw stepper motor. Correspondingly, the control component can be a single-chip microcomputer, a programmable logic controller (PLC), etc., or it can be a driver program provided by the fixed-axis screw stepper motor. Physically, the control component can be a separate component separated from the gas operating mechanism 20, or it can be fixed to the gas operating mechanism 20, or it can be a part of the gas operating mechanism 20 itself. For example, the driver program provided by the fixed-axis screw stepper motor can be the control component.

[0085] like Figures 4 - 6 As shown, the movement direction of the piston 213 is parallel to the movement direction of the power output shaft. The power output shaft of the second drive assembly 22 is connected to the piston 213 via the motion linkage 24 to drive the piston 213. Specifically, the motion linkage 24 is a strip-shaped plate with one end fixed to the piston 213 and the other end fixed to the power output shaft of the second drive assembly 22, thereby linking the piston 213 with the power output shaft. In this way, the second drive assembly 22 can drive the piston 213 with a simple structure. It is understood that the motion linkage 24 can also have other shapes.

[0086] In some embodiments, as Figures 6 - 8As shown, the gas transmission channel may be a gas conduit 25. One end of the gas conduit 25 that is hermetically docked to the second opening 12 includes a nozzle 251 that matches the second opening 12. Through the gas conduit 25, it is convenient for the gas operating mechanism 20 and the pipette cylinder 10 to communicate. That is to say, the second opening 12 and the fifth opening 212 are communicated through the intermediary of the gas conduit 25, and the communication is more convenient. Moreover, in this embodiment, the pipette cylinder 10 is detachably connected to the gas operating mechanism 20. Through the gas conduit 25, it is also more convenient for the detachable connection between the gas operating mechanism 20 and the pipette cylinder 10. It can be understood that the gas transmission channel may not be a conduit. For example, the second opening 12 and the fifth opening 212 may be directly communicated, and the second opening 12 and / or the fifth opening 212 may complete the communication of the two openings through a protruding part, and the gas transmission channel may be a pipeline inside the protruding part.

[0087] It should be noted that whether the gas operating mechanism 20 and the pipette cylinder 10 are fixedly connected or detachably connected has no necessary relationship with whether the fifth opening 212 and the second opening 12 are directly communicated or communicated through an intermediary. For example, the fifth opening 212 and the second opening 12 may be directly communicated and may also be detachably connected, but the disassembly is not as convenient as the way of communicating through an intermediary.

[0088] In this application, the nozzle 251 is used to insert into the second opening 12. The gas conduit 25 is provided with the nozzle 251, which can make the communication between the second opening 12 and the fifth opening 212 more convenient, and can also make the connection between the two more firm, and the gas transmission process more stable. It can be understood that the nozzle 251 can also be connected to the second opening 12 by sleeving.

[0089] In some embodiments, the nozzle 251 may be inserted into the second opening 12 of the pipette cylinder 10 to a preset depth. The preset depth is a depth that makes the connection between the two more firm and stable. For example, the preset depth may be more than twice the diameter of the nozzle 251. In some embodiments, there may be an interference fit between the nozzle 251 and the second opening 12 of the pipette cylinder 10, that is, a certain pressure needs to be applied to insert the nozzle 251 into the second opening 12 to the preset depth. In some embodiments, a fourth sealing ring 164 may be provided between the nozzle 251 and the second opening 12 of the pipette cylinder 10.

[0090] In some embodiments, such as Figure 7As shown, the gas conduit is arranged in a U shape, and both the fifth opening 212 and the second opening 12 are at one end of the U-shaped opening of the gas conduit. Specifically, in the normal working direction of the pipette, the gas conduit 25 passes through the frame plate 23 from below the frame plate 23, then extends a preset distance in the horizontal direction and then passes through the frame plate 23 downward. One end that passes through the frame plate 23 downward includes the nozzle 251. Since the air cylinder 21 has a preset height in the vertical direction and the fifth opening 212 is located at the bottom end of the air cylinder 21, by passing through the frame plate 23 upward and then passing through it again, the height of the nozzle 251 in the vertical direction can be increased, so that the pipette cylinder 10 is closer to the frame plate 23 in the height direction, thereby reducing the total height of the entire pipette in the vertical direction and making the structure of the pipette more compact. After the gas conduit 25 is provided, the gas flow of the gas operating mechanism 20 can be seen in Figure 7 . Since the mass of the gas is relatively small, although the direction changes multiple times, it will not affect the liquid transfer of the pipette. Figure 8 What is shown is the situation where the gas operating mechanism 20 outputs gas. If the gas operating mechanism 20 extracts gas, the direction of gas flow is opposite.

[0091] In some embodiments, as Figure 8 and Figure 9 shown, the gas operating mechanism 20 may further include a disassembly mechanism for separating the pipette cylinder 10 from the gas operating mechanism 20. The disassembly mechanism includes a disassembly wrench 31 and a third drive assembly 32. Among them:

[0092] The disassembly wrench 31 can move along the direction in which the air delivery channel is connected to the second opening 12 to push the pipette cylinder 10 so that the pipette cylinder 10 is separated from the gas operating mechanism 20. In some embodiments, the disassembly wrench 31 is sleeved on the nozzle 251 and can move along the direction in which the nozzle 251 is inserted into the second opening 12 to push and press the pipette cylinder 10 so that the pipette cylinder 10 is disconnected from the nozzle 251; that is, the disassembly wrench 31 can push the pipette cylinder 10 away along the direction in which the nozzle 251 is inserted into the second opening 12. The installation of the pipette cylinder 10 on the gas operating mechanism 20 and the disassembly process can be seen in Figure 8 and Figure 9。In some embodiments, a through hole may be formed in the portion of the disassembly wrench 31 sleeved on the nozzle 251 to sleeved on the nozzle 251. The diameter of the through hole is greater than the diameter of the nozzle 251, so that the wrench can slide freely on the nozzle 251. By forming the through hole and sleeving it on the nozzle 251, the axis of the through hole of the disassembly wrench 31 is aligned with the axis of the nozzle 251, that is, aligned with the axis of the second opening 12, making the force on the disassembly wrench 31 more balanced, which is beneficial to reducing the damage of the disassembly wrench 31. In addition, the above-mentioned matching method also avoids adding an additional guiding structure for guiding the movement of the disassembly wrench 31 on the gas operating mechanism 20, which is beneficial to simplifying the structure.

[0093] Exemplarily, the third driving assembly 32 is used to drive the movement of the disassembly wrench 31. Through the third driving assembly 32, the disassembly of the pipette cylinder 10, that is, the separation of the pipette cylinder 10 from the gas operating mechanism 20, can be made faster. In some embodiments, the third driving assembly 32 may be fixed to the frame plate 23 and includes an output shaft capable of linear movement, and the moving direction of the output shaft may be parallel to the disassembly movement direction of the disassembly wrench 31. A through hole may also be formed in the opposite end of the portion of the disassembly wrench 31 sleeved on the nozzle 251, and it is sleeved and fixed on the output shaft of the third driving assembly 32. In some embodiments, the disassembly wrench 31 may be clamped and fixed by two nuts, and an external thread matching the nut is machined on the output shaft of the third driving assembly 32. In some embodiments, the third driving assembly 32 may be a telescopic cylinder.

[0094] In some embodiments, the pipette may further include a manipulator (not shown in the figure) matching the pipette cylinder 10 to drive the pipette cylinder 10 to move to a position where it is docked with the gas transmission channel. That is, the pipette cylinder 10 is driven to move so that the second opening 12 is hermetically docked with the nozzle 251.

[0095] In some embodiments, the manipulator may drive the movement of the pipette cylinder 10 by clamping the pipette cylinder 10 and then driving the pipette cylinder 10 to move. In some embodiments, the manipulator may also clamp and hold the pipette cylinder 10 and keep it fixed when disassembling the pipette cylinder 10 to prevent the pipette cylinder 10 from falling downward after being pushed away by the disassembly wrench 31.

[0096] It should be understood that the above embodiments are all exemplary and do not cover all possible implementation manners included in the claims. Without departing from the scope of the present disclosure, various deformations and changes can also be made on the basis of the above embodiments. Similarly, the technical features of the above embodiments can also be arbitrarily combined to form additional embodiments of the present invention that may not be explicitly described. Therefore, the above embodiments only represent several implementation manners of the present invention and do not limit the protection scope of the present invention patent.

Claims

1. A pipette cylinder, characterized in that, Comprising: A cylinder body having a first accommodation cavity therein, and the cylinder body is provided with a first opening and a second opening that communicate the first accommodation cavity with the external environment; A hollow guide rod, at least part of which is located in the first accommodation cavity, and the hollow guide rod has a second accommodation cavity; the hollow guide rod has a third opening that communicates the second accommodation cavity with the first accommodation cavity and a fourth opening that communicates the second accommodation cavity; the outer side wall of the end of the hollow guide rod provided with the fourth opening is hermetically docked with the side wall of the second opening; The hollow guide rod is movable to switch between a closed state and an open state; the hollow guide rod has a closed portion located in the first accommodation cavity; when the hollow guide rod is in the closed state, the closed portion of the hollow guide rod closes the first opening; when the hollow guide rod is in the open state, the closed portion of the hollow guide rod disengages from the first opening; The first opening and the second opening are arranged opposite to each other, and the arrangement direction of the first opening and the second opening is a first direction; the cylinder body has a guiding structure for guiding the relative movement of the hollow guide rod along the first direction with respect to the cylinder body, so that the hollow guide rod switches between the closed state and the open state; The pipette cylinder further includes a first driving assembly for driving the hollow guide rod to move; A magnetic attracting member cooperating with the first driving assembly is provided on the hollow guide rod; the first driving assembly includes an electromagnet and a reset member; The pipette cylinder further includes a partition plate that divides the first accommodation cavity into a first sub-cavity and a second sub-cavity in the first direction; The first sub-cavity communicates with the first opening, and the second sub-cavity communicates with the second opening; The hollow guide rod passes through the partition plate, the third opening of the hollow guide rod is located in the first sub-cavity, and the fourth opening is located in the second sub-cavity; Both the electromagnet and the reset member are installed in the second sub-cavity; The cylinder body includes: A first cylinder body having the first sub-cavity, and the end plate at the end of the first cylinder body away from the first opening in the first direction is the partition plate; A second cylinder body fixed to the end of the first cylinder body having the partition plate; one end of the reset member abuts against the inner end wall of the end of the second cylinder body away from the first cylinder body, and the other end abuts against the hollow guide rod; A third cylinder body fixed to the end of the second cylinder body away from the first cylinder body, and the electromagnet is accommodated in the third cylinder body; the inner cavities of the third cylinder body and the second cylinder body communicate with each other to form the second sub-cavity.

2. The pipetting cylinder according to claim 1, wherein, The electromagnet matches the magnetic attracting member to attract the magnetic attracting member in the energized state, and drives the hollow guide rod to switch from the closed state to the open state; the reset member is used to push the hollow guide rod to switch from the open state to the closed state when the electromagnet is de-energized.

3. The pipetting cylinder according to claim 2, characterized in that, The guiding structure is a through hole opened on the partition plate, and the diameter of the through hole is greater than a preset value of the diameter of the hollow guide rod.

4. A pipette, characterized in that, Comprising: The pipette cylinder according to any one of claims 1 to 3.

5. The pipette according to claim 4, characterized in that, The pipette further includes: A gas operating mechanism having a gas transmission channel that seals and docks with a fourth opening of the second accommodating chamber; the gas operating mechanism sucks or discharges gas through the gas transmission channel so that a first opening of the pipette cylinder sucks or discharges a preset volume of liquid.

6. The pipette according to claim 5, characterized in that, The gas operating mechanism includes a cylinder, and the cylinder includes: A cylinder body having a third accommodating chamber; one end of the cylinder body is provided with a fifth opening communicating with the third accommodating chamber, and the fifth opening is hermetically docked with the gas transmission channel; A piston located in the third accommodating chamber and capable of moving relative to the cylinder body within the third accommodating chamber.

7. The pipette according to claim 6, characterized in that, The gas operating mechanism further includes: A second driving assembly for driving the piston to move relative to the cylinder body.

8. The pipette according to claim 7, characterized in that, The gas operating mechanism further includes: A motion linkage member for realizing the linkage between the piston and the second driving assembly, and both the cylinder and the second driving assembly are located on the same side of the motion linkage member.

9. The pipette according to any one of claims 6-8, characterized in that, The gas transmission channel is a gas conduit, and one end of the gas conduit hermetically docked to the second opening includes a gas nozzle matching the second opening.

10. The pipette according to claim 9, characterized in that, The gas conduit is arranged in a U shape, and both the fifth opening and the second opening are at one end of the U-shaped opening of the gas conduit.

11. The pipette according to claim 9, characterized in that, The pipette further includes a manipulator matching the pipette cylinder to drive the pipette cylinder to move to a position docked with the gas transmission channel.

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