Rotary dispensing valve device with microfluidic

Abstract

The application discloses a rotary distribution valve device with micro flow paths, which comprises a stator assembly, a rotor assembly, a sealing gasket and a flow path plate with multiple micro flow paths. The stator assembly comprises a stator shell, multiple flow path tubes and a sealing gasket. The multiple flow path tubes are arranged in the stator shell in a circle. The sealing gasket comprises an annular gasket and a plug tube. The plug tube is inserted into the flow path tube one by one. The annular gasket is provided with a first flow hole corresponding to the plug tube. Each micro flow path in the flow path plate is connected with a probe for reagent inlet and outlet. The rotor assembly is rotatably connected to the top of the stator assembly. The distribution valve is installed in the reagent box and is disposable. The distribution valve does not need to be disassembled and maintained. The distribution valve can be discarded after detection, thereby reducing the maintenance cost.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical supplies, and particularly relates to a rotary distribution valve device with a micro flow path. BACKGROUND

[0002] Currently, an integrated reagent kit (package) used by an analysis instrument generally contains multiple soft reagent bags for containing different reagents and waste liquid recovery bags for avoiding biological pollution. The reagent bags in the package control the flow direction and cutoff of the reagents through specific channels and a distribution valve device. The existing distribution valve devices are arranged on the reagent package or the instrument. (1) The distribution valve device is integrated in the reagent package: the reagent types through the distribution valve device are few, the structure is relatively simple, and the function is relatively single; (2) The distribution valve device is arranged on the main machine: an electromagnetic valve + flow path plate structure is adopted, the channels are also few, the structure is complex, and the cost is high. In an emergency, when the instrument measurement data is abnormal, the instrument needs to be disassembled, and the flow path pipeline needs to be maintained, which will cause a delay in the battle, a delay in diagnosis, and even cause an unimaginable consequence. Since the flow path pipeline (including the distribution valve device) exists in the analysis instrument, it needs to be replaced regularly, cannot be discarded after the reagents are used, has a high maintenance cost, and also brings inconvenience and increases the risk to the user. SUMMARY

[0003] The present application solves the technical problem of providing a rotary distribution valve device with a micro flow path, which can effectively solve the problem of the existing technology that needs to be replaced regularly and has a high maintenance cost.

[0004] In order to solve the above technical problems, the technical scheme adopted by the present application is as follows:

[0005] A rotary distribution valve device with a micro flow path, the rotary distribution valve device comprising a stator assembly, a rotor assembly, a sealing gasket and a flow path plate with multiple micro flow channels built-in, the stator assembly comprising a stator shell, flow path pipes and a sealing gasket, the stator shell being fixedly arranged on the flow path plate, the sealing gasket being arranged on the stator shell, the flow path pipes being provided in plurality, the plurality of flow path pipes being arranged in a circle in the stator shell, the lower ends of the plurality of flow path pipes being respectively communicated with the corresponding micro flow channels in the flow path plate, the sealing gasket comprising an annular gasket and a plurality of insertion tubes, the plurality of insertion tubes being fixedly arranged on the bottom of the annular gasket and arranged in a circle, the insertion tubes being one-to-one correspondingly inserted with the flow path pipes, the annular gasket being provided with first flow holes corresponding to the insertion tubes, each micro flow channel in the flow path plate being respectively connected with a probe for reagent inlet and outlet, the rotor assembly being rotatably connected above the stator assembly, the rotor assembly being provided with an inlet and outlet channel, when the rotor assembly is rotated to a certain angle, the inlet and outlet channel is communicated with one of the first flow holes.

[0006] As a preferred scheme of the present application, the rotor assembly comprises a rotor and a rotor fixing block, the rotor is rotatably connected above the stator assembly, the flow path plate and the stator assembly are both provided with an installation hole through which the rotor shaft can pass, the rotor is fixedly connected with the rotor fixing block through a screw, and the rotor fixing block is rotatably connected with the bottom of the flow path plate as the rotor shaft.

[0007] As a preferred scheme of the present application, the rotor comprises a flat sheet and a gear, the top surface of the gear is provided with a first cavity, the center of the first cavity is provided with a conical boss, the conical boss is provided with an inlet and outlet hole in communication with the inlet and outlet channel, the bottom surface of the gear is provided with a second cavity, and the inlet and outlet channel is sealed by the solder between the flat sheet and the second cavity.

[0008] As a preferred scheme of the present application, the periphery of the conical boss is provided with a plurality of residual liquid recovery openings, the flat sheet is provided with a residual liquid recovery groove at the corresponding position of the residual liquid recovery opening, and the rotor fixing block is provided with a residual liquid recovery channel in communication with the residual liquid recovery groove.

[0009] As a preferred scheme of the present application, the bottom surface of the rotor is provided with a wear-resistant gasket between the bottom surface of the rotor and the sealing gasket.

[0010] As a preferred scheme of the present application, the wear-resistant gasket is provided with a plurality of upper bosses and a plurality of lower bosses, the lower bosses are inserted into the first flow holes one by one, the upper bosses and the lower bosses at the same vertical position are in communication to form second flow holes, and the first flow holes and the second flow holes are in one-to-one correspondence.

[0011] As a preferred scheme of the present application, the flow path plate is provided with a light guide strip, the bottom periphery of the gear is provided with a skirt, one end of the light guide strip is located below the skirt of the gear, and the skirt is provided with a light passing hole at the corresponding position of the light guide strip.

[0012] As a preferred scheme of the present application, the light guide strip is transparent, and the gear is opaque black.

[0013] As a preferred scheme of the present application, the flow path plate is provided with a waste liquid recovery opening, and the flow path plate is provided with a micro flow channel connected with the waste liquid recovery opening.

[0014] As a preferred scheme of the present application, a filter core is arranged between the flow path tube and the micro flow channel.

[0015] The present application provides a rotating distribution valve device with a micro flow channel, which has the following beneficial effects compared with the prior art:

[0016] In use, the distribution valve device is installed in the reagent box, one probe is communicated with the waste liquid bag, and the remaining probes are connected with different reagent bags respectively, when the analysis instrument issues an instruction to extract the calibration liquid or the quality inspection liquid, the driving end of the instrument drives the rotor to rotate by a certain angle, so that the inlet and outlet channels are communicated with the first flow holes, the cannula and the flow path tube corresponding to the reagent, the reagent is extracted to the instrument interior through the sampling needle on the instrument, and instrument calibration can be carried out; when the analysis instrument issues an instruction to extract the cleaning liquid, the driving end of the instrument drives the rotor to continue to rotate by a certain angle, so that the inlet and outlet channels are communicated with the first flow holes, the cannula and the flow path tube corresponding to the reagent, the reagent is extracted to the instrument interior through the sampling needle on the instrument, and flow path cleaning can be carried out; in this way, mutual pollution between multiple reagents can be ensured; in addition, due to high integration of the flow path and short flow path, the concentration of the reagent containing gas standard can be stabilized, and the accuracy of detection can be ensured; according to the application, the distribution valve is installed in the reagent box, and the distribution valve is discarded with the reagent box after the reagent is used up, so that the instrument does not need to be disassembled and maintained, and can be discarded after detection is completed, thereby reducing maintenance cost. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the application, the drawings of the embodiments will be briefly introduced below.

[0018] Figure 1 is a structural schematic diagram of a rotary distribution valve device with a micro flow path provided by the embodiments of the application;

[0019] Figure 2 is an exploded view of a rotary distribution valve device with a micro flow path provided by the embodiments of the application;

[0020] Figure 3 is a sectional view of a rotary distribution valve device with a micro flow path provided by the embodiments of the application;

[0021] Figure 4 is a structural schematic diagram of a flow path plate;

[0022] Figure 5 is a structural schematic diagram of another view direction of a flow path plate;

[0023] Figure 6 is a structural schematic diagram of a rotor assembly;

[0024] Figure 7 is an exploded view of a rotor assembly.

[0025] Markings in the figure:

[0026] Stator assembly 1; Rotor assembly 2; Seal pad 3; Micro flow channel 4; Flow path plate 5; Stator housing 6; Flow path tube 7; Ring gasket 8; Cannula 9; First flow hole 10; Probe 11; Access channel 12; Rotor 13; Rotor fixing block 14; Screw 15; Flat sheet 16; Gear 17; First cavity 18; Conical boss 19; Access hole 20; Second cavity 21; Residual liquid recovery port 22; Residual liquid recovery groove 23; Residual liquid recovery channel 24; Wear-resistant gasket 25; Light guide strip 26; Skirt 27; Light transmission hole 28; Filter core 29; Flow path flat plate 30; Flow path groove plate 31; Raised center hole 32; Second flow hole 33; Waste liquid recovery port 34. DETAILED DESCRIPTION

[0027] The specific embodiments of the present application will be further described in conjunction with the drawings and examples. The following examples are used to illustrate the present application, but are not used to limit the scope of the present application.

[0028] In the description of the present application, it should be understood that the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only used to facilitate the description of the present application and simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application. It should be understood that the terms "first", "second", etc. are used to describe various information in the present application, but these information should not be limited to these terms, and these terms are only used to distinguish the same type of information from each other. For example, the "first" information can also be referred to as "second" information without departing from the scope of the present application, and similarly, the "second" information can also be referred to as "first" information.

[0029] As Figures 1 to 7As shown, the preferred embodiment of the present application provides a rotary distribution valve device with micro flow path, which comprises a stator assembly 1, a rotor assembly 2, a sealing gasket 3 and a flow path plate 5 with multiple micro flow channels 4, the stator assembly 1 comprises a stator housing 6, flow path tubes 7 and the sealing gasket 3, the stator housing 6 is fixed on the flow path plate 5, the sealing gasket 3 is covered on the stator housing 6, the flow path tubes 7 are provided in plurality, the plurality of flow path tubes 7 are arranged in a circle in the stator housing 6, the lower ends of the plurality of flow path tubes 7 are respectively communicated with the corresponding micro flow channels 4 in the flow path plate 5, the sealing gasket 3 comprises an annular gasket 8 and a plurality of insertion tubes 9, the plurality of insertion tubes 9 are fixed on the bottom of the annular gasket 8 and arranged in a circle, the insertion tubes 9 are correspondingly inserted with the flow path tubes 7, the annular gasket 8 is provided with first flow holes 10 corresponding to the insertion tubes 9, each micro flow channel 4 in the flow path plate 5 is respectively connected with a probe 11 for reagent access, the rotor assembly 2 is rotatably connected above the stator assembly 1, the rotor assembly 2 is provided with an access channel 12, when the rotor assembly 2 is rotated to a certain angle, the access channel 12 is communicated with one of the first flow holes 10.

[0030] In the embodiment, the flow path plate 5 comprises a flow path flat plate 30 and a flow path groove plate 31, the stator housing 6 is fixed on the flow path flat plate 30, the flow path flat plate 30 is fixedly connected with the flow path groove plate 31, the micro flow channels 4 are sealed by the solder between the flow path flat plate 30 and the flow path groove plate 31, wherein, in order to facilitate observation, the flow path groove plate 31 is transparent.

[0031] In use, the distribution valve device is installed in a reagent box, one probe 11 is communicated with a waste liquid bag, and the remaining probes 11 are respectively connected with different reagent bags, when the analysis instrument issues an instruction to extract a certain reagent, the driving end of the instrument drives the rotor to rotate to a certain angle, so that the access channel 12 is communicated with the first flow hole 10, the insertion tube 9 and the flow path tube 7 corresponding to the reagent, the reagent is extracted to the instrument through the sampling needle on the instrument, and the detection can be performed, after the detection is completed, the instrument drives the rotor to continue to rotate to a certain angle, so that the access channel 12 is communicated with the first flow hole 10, the insertion tube 9 and the flow path tube 7 corresponding to the waste liquid bag, and the waste liquid after detection is discharged from the instrument to the waste liquid bag through the sampling needle, thereby, not only the mutual contamination between multiple reagents can be ensured, but also the waste liquid after detection can be properly treated to prevent biological pollution; in addition, due to the high integration of the flow path and the short flow path, the concentration stability of the reagent containing gas standard can be ensured, and the detection accuracy can be ensured; by using the present application, since the distribution valve is installed in the reagent box and the distribution valve is disposable, it is not necessary to disassemble the instrument and maintain, and the instrument can be discarded after detection, thereby reducing the maintenance cost.

[0032] Exemplarily, the rotor assembly 2 comprises a rotor 13 and a rotor fixing block 14, the rotor 13 is rotatably connected above the stator assembly 1, the flow path plate 5 and the stator assembly 1 are both provided with installation holes for the rotor shaft, the rotor 13 is fixedly connected with the rotor fixing block 14 through a screw 15, and the rotor fixing block 14 is rotatably connected to the bottom of the flow path plate 5 as the rotor shaft.

[0033] Exemplarily, the rotor 13 comprises a flat sheet 16 and a gear 17, the top surface of the gear 17 is provided with a first cavity 18, the center of the first cavity 18 is provided with a conical boss 19, the conical boss 19 is provided with an inlet and outlet hole 20 communicating with the inlet and outlet channel 12, the bottom surface of the gear 17 is provided with a second cavity 21, and the inlet and outlet channel 12 is sealed by the solder between the flat sheet 16 and the second cavity 21. In specific implementation, other welding positions are arranged between the flat sheet 16 and the second cavity 21, so as to ensure the connection between the flat sheet 16 and the gear 17 and prevent falling off.

[0034] In specific implementation, in order to facilitate the assembly of the screw 15, the bottom of the flat surface is provided with a raised middle hole 32.

[0035] Exemplarily, the conical boss 19 is provided with a plurality of residual liquid recovery openings 22, the flat sheet 16 is provided with a residual liquid recovery groove 23 corresponding to the residual liquid recovery openings 22, and the rotor fixing block 14 is provided with a residual liquid recovery channel 24, which communicates with the residual liquid recovery groove 23. Such arrangement enables the residual liquid falling from the sampling needle on the instrument to slide off the conical boss 19 to the residual liquid recovery openings 22, flow along the residual liquid recovery groove 23 to the residual liquid recovery channel 24, and finally drop into the reagent box, thereby avoiding biological pollution.

[0036] Exemplarily, in order to prevent the sealing gasket 3 from being worn, a wear-resistant gasket 25 is arranged between the bottom surface of the rotor 13 and the sealing gasket 3.

[0037] Exemplarily, the wear-resistant gasket 25 is provided with a plurality of upper bosses and a plurality of lower bosses, the lower bosses are inserted into the first flow holes 10 one by one, the upper bosses and the lower bosses located at the same vertical position communicate with each other to form a second flow hole 33, and the first flow holes 10 and the second flow holes 33 communicate one by one. In this way, the rotation between the wear-resistant gasket 25 and the sealing gasket 3 can be prevented, and the contact area between the rotor assembly 2 and the wear-resistant gasket 25 is reduced by the arrangement of the upper bosses, thereby reducing friction.

[0038] In the embodiment, the tightness between the rotor assembly 2 and the wear pad 25 can be adjusted by the screw 15 to ensure that the rotor 13 is in sealing connection with the wear pad 25 when the rotor 13 rotates normally, and the pre-tightening force between the sealing pad 3 and the stator housing 6 enables the bottom plane of the wear pad 25 to be in close connection with the sealing pad 3 without leakage when the rotor rotates.

[0039] For example, the flow path plate 5 is provided with a light guide strip 26, the bottom periphery of the gear 17 is provided with a skirt 27, one end of the light guide strip 26 is located below the skirt 27 of the gear 17, and the skirt 27 is provided with a light transmission hole 28 corresponding to the light guide strip 26. In this way, the light emitted by the infrared light emitter on the sensor installed on the instrument is totally reflected by the light guide strip 26 and is received by the sensor through the light transmission hole 28, which indicates that the gear 17 has rotated to the initial zero position, and based on this, the rotation angle to other channels can be calculated by the number of steps of the gear 17, thereby ensuring the smooth detection of the reagent.

[0040] For example, in order to ensure stable transmission of the optical signal, the light guide strip 26 is transparent, and the gear 17 is opaque black.

[0041] For example, the flow path plate 5 is provided with a waste liquid recovery port 34, and the flow path plate 5 is provided with a micro flow path 4 connected with the waste liquid recovery port. In the embodiment, the probe 11 connected with the waste liquid recovery port 34 is provided with a waste liquid recovery bag, and after the instrument calibration or cleaning is completed, the waste liquid is driven by the pump body in the instrument to be transported to the waste liquid recovery port 34 through the external pipeline, and then is discharged to the waste liquid bag through the probe 11, thereby the waste liquid can be properly treated to prevent biological pollution.

[0042] For example, the flow path tube 7 and the micro flow path are provided with a filter core 29. The filter core can filter out solid substances in the reagent to prevent blockage.

[0043] In the description of the present application, it should be noted that unless otherwise specified and limited, the terms "connected", "connected" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0044] The above is only the preferred embodiment of the present application, and it should be noted that for those skilled in the art, without departing from the technical principles of the present application, a number of improvements and replacements can be made, which should also be considered as the protection scope of the present application.

Claims

1. A rotary dispensing valve device with micro flow paths provided in a cartridge, the rotary dispensing valve device being disposable with the cartridge, the rotary dispensing valve device being discarded with the cartridge after the reagents are used up, characterized in that, The rotating distribution valve device comprises a stator assembly, a rotor assembly, a sealing gasket and a flow path plate with multiple micro flow channels built-in, the stator assembly comprises a stator housing, flow path tubes and a sealing gasket, the stator housing is fixed on the flow path plate, the sealing gasket is covered on the stator housing, the flow path tubes are provided in multiple, the multiple flow path tubes are arranged in a circle in the stator housing, the lower ends of the multiple flow path tubes are communicated with the corresponding micro flow channels in the flow path plate respectively, the sealing gasket comprises an annular gasket and a plug, the bottom surface of the annular gasket is abutted with the upper end surface of the flow path tube, the plug is provided in multiple, the multiple plugs are fixed on the bottom of the annular gasket and arranged in a circle, the plug is inserted into the flow path tube one by one, the first flow holes corresponding to the plugs are arranged on the annular gasket, each micro flow channel in the flow path plate is connected with a probe for reagent access, the rotor assembly is rotatably connected above the stator assembly, the rotor assembly is provided with an access channel, when the rotor assembly is rotated to a certain angle, the access channel is communicated with one of the first flow holes.

2. A rotary distribution valve device with micro flow paths according to claim 1, characterized in that, The rotor assembly comprises a rotor and a rotor fixing block, the rotor is rotatably connected above the stator assembly, the flow path plate and the stator assembly are both provided with an installation hole through which the rotor shaft can pass, the rotor is fixedly connected with the rotor fixing block through a screw, the rotor fixing block is rotatably connected to the bottom of the flow path plate as the rotor shaft.

3. A rotary distribution valve device with micro flow paths according to claim 2, characterized in that The rotor comprises a flat sheet and a gear, the top surface of the gear is provided with a first cavity, the center of the first cavity is provided with a conical boss, the conical boss is provided with an access hole communicated with the access channel, the bottom surface of the gear is provided with a second cavity, the access channel is sealed by the solder between the flat sheet and the second cavity.

4. The rotary distribution valve device with micro flow paths according to claim 3, characterized by Multiple residual liquid recovery ports are arranged around the conical boss, residual liquid recovery grooves are arranged on the flat sheet corresponding to the residual liquid recovery ports, a residual liquid recovery channel is arranged on the rotor fixing block, the residual liquid recovery channel is communicated with the residual liquid recovery grooves.

5. The rotary distribution valve device with micro flow paths according to claim 3, characterized by A wear-resistant gasket is arranged between the bottom surface of the rotor and the sealing gasket.

6. A rotary dispensing valve device with microfluidic channels according to claim 5, wherein, The wear-resistant gasket is provided with multiple upper bosses and multiple lower bosses, the lower bosses are inserted into the first flow holes one by one, the upper bosses and the lower bosses located at the same vertical position are communicated to form second flow holes, the first flow holes and the second flow holes are communicated one by one.

7. The rotary distribution valve device with micro flow paths according to claim 5, characterized by A light guide strip is arranged on the flow path plate, a skirt is arranged on the bottom outer periphery of the gear, one end of the light guide strip is located below the skirt of the gear, a light transmission hole is arranged on the skirt corresponding to the light guide strip.

8. A rotary distribution valve device with micro flow paths according to claim 7, characterized in that The light guide strip is transparent, and the gear is opaque black.

9. The rotary distribution valve device with micro flow paths according to claim 1, characterized by A waste liquid recovery port is arranged on the flow path plate, and a micro flow channel connected with the waste liquid recovery port is arranged in the flow path plate.

10. The rotary distribution valve device with micro flow paths according to claim 1, characterized by A filter core is arranged between the flow path tube and the micro flow channel.

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