A composition with moisturizing effect, its preparation method and application

Abstract

This invention belongs to the field of daily chemical products technology, and particularly relates to a moisturizing composition, its preparation method, and its application. The moisturizing composition comprises soybean lecithin, *Alnus macrocarpa* seed oil, *Klebsiella macrocarpa* extract, and *Alternaria rubra* extract, wherein the mass ratio of soybean lecithin, *Alnus macrocarpa* seed oil, *Klebsiella macrocarpa* extract, and *Alternaria rubra* extract is (1-5):(1-10):(0.1-3):(0.5-5). Compared with existing technologies, this invention uses multiple plant extracts as active ingredients, employing a compounding of *Alnus macrocarpa* seed oil, *Klebsiella macrocarpa* extract, and *Alternaria rubra* extract, resulting in a synergistic effect of multiple active ingredients for multi-faceted moisturizing.

Description

Technical Field

[0001] This invention belongs to the field of daily chemical products technology, and in particular relates to a composition with moisturizing effect, its preparation method and application. Background Technology

[0002] Many cosmetics that claim to have moisturizing effects provide good immediate hydration when applied to the face, but after a while, dryness and tightness may occur. Alternatively, some cosmetics may feel sticky and heavy on the face, be difficult to absorb, have unsatisfactory moisturizing effects, and have a poor user experience.

[0003] Because natural plant extracts have their own color and odor, their use in cosmetics has always been restricted. Cosmetics that use natural plant oils as raw materials use certain extracts of certain natural plants as functional additives. However, the added extracts are only an auxiliary part, providing certain auxiliary functions. The main function is still the added chemical additives.

[0004] In addition, traditional plant extraction processes can only be carried out after the plants are harvested and dried. The variable factors in the harvesting and drying conditions can seriously affect the reproducibility of the plant raw material components, making it impossible to extract all the active substances in the fresh plant cells. Moreover, it can destroy the natural synergistic effects between different compounds, thereby weakening or completely losing the desired multifunctional properties of natural compounds. Summary of the Invention

[0005] Addressing the issue of poor moisturizing effects in some existing cosmetics, this invention provides a moisturizing composition, its preparation method, and its application. This invention uses multiple plant extracts as active ingredients, combining Aldera macrophylla seed oil, giant kelp extract, and red algae extract. The synergistic effect of these active ingredients provides multi-faceted moisturizing.

[0006] The objective of this invention can be achieved through the following technical solutions:

[0007] The present invention provides a composition with moisturizing effect, which is composed of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract, wherein the mass ratio of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract is (1-5):(1-10):(0.1-3):(0.5-5).

[0008] In one embodiment of the present invention, preferably, in the composition having moisturizing effect, the mass ratio of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract is (1-5):(2-10):(1-3):(1-5).

[0009] In one embodiment of the present invention, more preferably, the composition having moisturizing effect contains soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract in a mass ratio of 1:10:1:1.

[0010] The present invention further provides a method for preparing a composition with moisturizing effects, comprising the following steps:

[0011] Step S1: Homogenize soybean lecithin, giant kelp extract, and red algae extract at high speed until they are evenly dispersed, so that the giant kelp extract and red algae extract are coated with soybean lecithin.

[0012] Step S2: Add the seed oil of Aldera macrophylla to the substance obtained in step S1 to obtain a composition with moisturizing effect.

[0013] In one embodiment of the present invention, the conditions for high-speed homogenization in step S1 are: 1-3 atmospheres, temperature of 30-65°C (e.g., 40°C, 50°C, 60°C, etc. can be selected), rotation speed of 1000-4000 r / min, and time of 20-40 min.

[0014] In step S1 of this invention, a high-speed homogenization method is used to encapsulate the extracts of giant kelp and red algae with soybean lecithin. Compared with adding the extracts of giant kelp and red algae separately, the encapsulation with soybean lecithin can promote the absorption of active substances by the skin.

[0015] The present invention further provides the application of a composition with moisturizing effects, wherein the composition with moisturizing effects is added to cosmetics or skin care products.

[0016] The present invention further provides a cosmetic or skin care product with moisturizing effect, comprising the composition with moisturizing effect and cosmetic or skin care excipients, wherein the cosmetic or skin care product with moisturizing effect uses the composition with moisturizing effect as an active ingredient, and the composition with moisturizing effect has a mass fraction of 10-50% in the cosmetic or skin care product.

[0017] In one embodiment of the present invention, preferably, the composition having moisturizing effect has a mass fraction of 10-20% in cosmetics or skin care products.

[0018] In one embodiment of the present invention, the excipients for cosmetics or skin care products include one or a combination of surfactants, powder materials, thickeners, conditioning agents, moisturizers, preservatives, chelating agents, and deionized water.

[0019] Surfactants, thickeners, conditioning agents, humectants, preservatives, and chelating agents can be selected from conventional options used in the cosmetics industry. For example, surfactants can be selected from glyceryl stearate, PEG-100 stearate, cetearyl glucoside, etc.; thickeners can be selected from xanthan gum, carbomer, acrylates / C10-30 alkanol acrylate crosspolymers, etc.; conditioning agents can be selected from meadowfoam seed oil, squalane, caprylic / capric triglycerides, hydrogenated polydecene, etc.; humectants can be selected from polyols, sodium hyaluronate, betaine, trehalose, etc. Using sodium hyaluronate and glycerin together enhances the moisturizing effect and saves costs; preservatives can be selected from phenoxyethanol, p-hydroxyacetophenone, polyols (such as hexanediol), etc., among which p-hydroxyacetophenone and hexanediol combined can enhance the preservative effect; chelating agents can be selected from EDTA salts, etc.

[0020] The present invention further provides a moisturizing serum, which comprises the following components in weight percentage:

[0021]

[0022] In one embodiment of the present invention, preferably, the moisturizing serum comprises the following components in weight percentages:

[0023]

[0024]

[0025] In this invention, the moisturizing composition includes Alder seed oil, a liquid oil similar to natural human sebum with high unsaturation, which allows it to quickly penetrate the skin barrier and reach subcutaneous tissue. Giant kelp extract, primarily containing polysaccharides, carries moisture deep into the skin. Red algae extract reduces TNF-α levels, thus reducing inflammation and redness, promoting membrane protein formation, strengthening the skin's protective barrier, and preventing moisture loss. Simultaneously, the composition and ratio of unsaturated fatty acids in Alder seed oil effectively promote the absorption of oils and nutrients, forming a natural protective film on the skin to prevent moisture and nutrient loss.

[0026] In addition, the giant kelp extract in this invention also has the effects of repairing the skin barrier and protecting skin stem cells from the stimulation of pollutants, while the red algae extract also has the effects of inhibiting allergies, fighting inflammation, promoting cell proliferation, and repairing the skin barrier.

[0027] In this invention, both the giant kelp extract and the red algae extract are obtained using Zeta fraction technology. Zeta fraction technology can extract complete active ingredients from fresh plants; it is a sustainable, solvent-free extraction technology that uses magnetron pulse technology for targeted separation. The entire process requires no chemical reagents or water as a solvent. Furthermore, this invention uses Aldera macrocarpa seed oil combined with lecithin-encapsulated giant kelp extract and red algae extract to promote skin absorption of the active substances.

[0028] The raw materials used in this invention are all mild and non-irritating, suitable for sensitive skin, and the application method is simple and harmless to the skin. This invention utilizes Zeta fraction technology to extract complete active ingredients from fresh plants, without the need for added chemical reagents or water as a solvent.

[0029] In this invention, since the seed oil of *Alternanthera philoxeroides* is an oily liquid, and the extracts of giant kelp and red algae are water-soluble substances, direct combination would result in uneven mixing and poor quality stability of the composition. This invention employs a high-speed homogenization method to encapsulate the extracts of giant kelp and red algae with soybean lecithin before mixing them with the seed oil of *Alternanthera philoxeroides*, thereby improving the stability of the composition and its ability to penetrate the skin.

[0030] In addition to moisturizing effects, the composition of this invention also has the effects of repairing the skin barrier, fighting inflammation, soothing allergies, and balancing oil secretion. Detailed Implementation

[0031] This invention provides a moisturizing serum that is effective and long-lasting. The components and proportions of the moisturizing serum provided by this invention are as follows:

[0032] Table 1. Proportions of Components in Moisturizing Serums

[0033] Components Proportion Deionized water margin Sodium hyaluronate 0.1％-1％ Trehalose 1％-10％ Hydroxyethyl cellulose 0.1％-5％ Hansheng Glue 0.1％-10％ Panthenol 1％-5％ glycerin 1％-10％ 1,2-Pentanediol 0.1％-0.8％ Soy lecithin 1％-5％ Large-leaf alfalfa seed oil 1％-10％ Giant kelp extract 0.1％-3％ Red algae extract 0.5％-5％

[0034] A moisturizing serum is prepared using the following process steps:

[0035] (1) Weigh each component according to the proportion.

[0036] (2) Add sodium hyaluronate, trehalose, hydroxyethyl cellulose, xanthan gum and deionized water into a water pot, heat to 80°C, stir until completely dissolved, and continue stirring for half an hour.

[0037] (3) After step (2) is completed, stir and cool down. When the temperature drops below 30°C, add panthenol, glycerol and 1,2-pentanediol respectively, and stir until completely dissolved.

[0038] (4) Add soybean lecithin, giant kelp extract, and red algae extract to a high-speed homogenizer and homogenize at 60°C until uniformly dispersed. The conditions for high-speed homogenization are: 2 atmospheres, rotation speed of 3000 r / min, and time of 30 min.

[0039] (5) Add the mixture obtained in step (4) to the mixture obtained in step (3), stir evenly, then add the large-leaf alder seed oil, stir evenly to obtain the essence.

[0040] This invention further provides the moisturizing effect of the serum.

[0041] The study included 90 healthy Chinese women with sensitive skin, aged 25 to 45 years (mean age 33.50 years). All participants provided informed consent in writing. Participants were willing to cooperate and understand the necessity and duration of the treatment to adhere to the protocol established by the clinical trial center. The 120 participants were divided into 12 groups of 10 each. Each group applied the serums from Examples 1, 2, 3, and Comparative Examples 1-9 to the entire face, twice daily (morning and evening) for 28 consecutive days. Skin moisture content in the stratum corneum was measured by a Corneometer CM825 on days 0, 14, and 28. Data were analyzed using SPSS 28.0. Normality was tested; if the data were normally distributed, a t-test was used; otherwise, a rank-sum test was used. Ordinal data were analyzed using the rank-sum test. The statistical significance level was defined as p < 0.05.

[0042] The present invention will now be described in detail with reference to specific embodiments.

[0043] Examples 1, 2, 3, and Comparative Examples 1-7

[0044] Examples 1, 2, and 3 and Comparative Examples 1-7 provide different moisturizing serums, and their respective ingredient compositions are shown in Table 2.

[0045] Table 2. Raw material composition ratios of Examples 1, 2, 3 and Comparative Examples 1-7

[0046]

[0047]

[0048] The preparation process flow of the serums in Examples 1, 2, and 3 and Comparative Examples 1-7 is shown below:

[0049] (1) Weigh each component according to the proportion.

[0050] (2) Add sodium hyaluronate, trehalose, hydroxyethyl cellulose, xanthan gum and deionized water into a water pot, heat to 80°C, stir until completely dissolved and continue stirring for half an hour.

[0051] (3) After step (2) is completed, stir and cool down. When the temperature drops below 30°C, add panthenol, glycerol and 1,2-pentanediol respectively, and stir until completely dissolved.

[0052] (4) Soybean lecithin (if the amount added in Table 2 is 0%, then do not add it) and giant kelp extract (if the amount added in Table 2 is 0%, then do not add it) and red algae extract (if the amount added in Table 2 is 0%, then do not add it) are homogenized at 60°C at high speed until they are evenly dispersed. The specific homogenization conditions are 2 atmospheres, 3000 r / min, and 30 min.

[0053] (5) Add the mixture obtained in step (4) to the mixture obtained in step (3), stir evenly, and add the large-leaf alder seed oil (if the amount added in Table 2 is 0%, then do not add it), stir evenly to obtain the essence.

[0054] Comparative Example 8: Compared with Example 1, the giant kelp extract and red algae extract were replaced with 2% Centella asiatica extract, while the rest was the same as in Example 1. The preparation process is as follows:

[0055] (1) Weigh each component according to the proportion.

[0056] (2) Add sodium hyaluronate, trehalose, hydroxyethyl cellulose, xanthan gum and deionized water into a water pot, heat to 80°C, stir until completely dissolved, and continue stirring for half an hour.

[0057] (3) After step (2) is completed, stir and cool down. When the temperature drops below 30°C, add panthenol, glycerol and 1,2-pentanediol respectively, and stir until completely dissolved.

[0058] (4) Homogenize soybean lecithin and Centella asiatica extract at 60°C until they are evenly dispersed.

[0059] (5) Add the mixture obtained in step (4) to the mixture obtained in step (3), stir evenly, add the large-leaf aralia seed oil, stir evenly to obtain the essence.

[0060] Comparative Example 9: Compared with Example 3, the giant kelp extract and red algae extract were replaced with 3.5% Centella asiatica extract, otherwise the preparation process was the same as in Example 3. The preparation process is as follows:

[0061] (1) Weigh each component according to the proportion.

[0062] (2) Add sodium hyaluronate, trehalose, hydroxyethyl cellulose, xanthan gum and deionized water into a water pot, heat to 80°C, stir until completely dissolved, and continue stirring for half an hour.

[0063] (3) After step (2) is completed, stir and cool down. When the temperature drops below 30°C, add panthenol, glycerol and 1,2-pentanediol respectively, and stir until completely dissolved.

[0064] (4) Homogenize soybean lecithin and Centella asiatica extract at 60°C until they are evenly dispersed.

[0065] (5) Add the mixture obtained in step (4) to the mixture obtained in step (3), stir evenly, add the large-leaf aralia seed oil, stir evenly to obtain the essence.

[0066] The Corneometer CM825 was used to measure the moisture content of the stratum corneum. A higher measurement indicates an increase in the moisture content of the stratum corneum.

[0067] The skin stratum corneum moisture content and the rate of change of stratum corneum moisture content of the serums of Examples 1, 2, 3 and Comparative Examples 1-9 are shown in Tables 3 and 4 (the data in the tables are the average data of 10 subjects in each group).

[0068] Table 3. Moisture content of the stratum corneum of the skin

[0069]

[0070]

[0071] Table 4. Change rate of moisture content in the stratum corneum

[0072]

[0073]

[0074] As shown in Tables 3 and 4, compared with before use, after 14 days of use of the sample from Example 1, the moisture content of the stratum corneum of the skin increased significantly by 23.06%, and after 28 days of use, the moisture content of the stratum corneum of the skin increased significantly by 40.39%. Example 1, which contains both Aldera macrophylla seed oil, giant kelp extract, and red algae extract, showed better moisturizing effects than Comparative Examples 1-7, which contained only two or one of these three ingredients, demonstrating that Aldera macrophylla seed oil, giant kelp extract, and red algae extract have a synergistic effect.

[0075] In Comparative Examples 8 and 9, Centella asiatica extract can tighten the connection between the epidermis and dermis, achieving a firming and smoothing effect on the skin. However, its moisturizing effect is not as good as that of deep-sea giant kelp extract and red algae extract. Furthermore, both Centella asiatica extract and Aldera macrophylla seed oil have the effect of repairing the skin barrier, and the combination did not achieve a synergistic effect. Therefore, the use of giant kelp extract and red algae extract in Examples 1 and 3 of this application has a better moisturizing effect than the use of Centella asiatica extract in Comparative Examples 8 and 9.

[0076] Eight-week-old female C57 mice were randomly divided into an experimental group (Examples 1-3 and Comparative Examples 1-9) and a control group (compared to the experimental group, the control group had its serum replaced with physiological saline), with five mice in each group. Hair was removed from the nape of the neck of all mice in each group. Medical tape was applied tightly to the skin on the back of the shaved mice and then quickly removed. Each mouse underwent modeling stimulation twice daily, with each stimulation involving five repetitions of the "tape application-removal" process. The interval between the two stimulations was approximately 8 hours, and the modeling process continued for 5 days. After modeling, the mice's skin showed redness but no bleeding. Sterile gauze was cut into 1cm*1cm squares. Serum (experimental group) and physiological saline (control group) were drawn up with syringes and transferred to the gauze. The gauze was applied to the site of mechanical barrier damage on the mouse skin and gently patted for 3 minutes until absorbed. This treatment (either the serum of the experimental group or the physiological saline of the control group) continued for 14 days. After the last administration, the water content and oil content of the skin on the back of the mice were measured using a skin moisture meter. The same test site was measured three times, and the average value was taken.

[0077] Table 5. Changes in skin moisture and lipid content in mice of each group.

[0078]

[0079]

[0080] The data in Table 5 are the average values ​​for each group of 5 mice. Because the skin has self-repairing capabilities, the water and oil content of the control group was also increased. Compared with the control group, the skin water and oil content of mice in Examples 1-3 and Comparative Examples 1-9 were significantly increased, suggesting that this serum can enhance skin water and oil content. The increased oil content indicates that the skin is less prone to sensitivity. Its effect may be related to the good moisturizing properties of the composition, which can maintain a certain level of hydration in areas of damaged skin barrier and promote skin barrier repair.

[0081] The above description of the embodiments is provided to enable those skilled in the art to understand and use the invention. It will be apparent to those skilled in the art that various modifications can be made to these embodiments, and the general principles described herein can be applied to other embodiments without inventive effort. Therefore, the present invention is not limited to the above embodiments, and any improvements and modifications made by those skilled in the art based on the disclosure of the present invention without departing from the scope of the invention should be within the protection scope of the present invention.

Claims

1. A composition having moisturizing effects, characterized in that, It is composed of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract, wherein the mass ratio of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract is (1-5):(2-10):(1-3):(1-5). Among them, the extracts of giant kelp and red algae are encapsulated in soybean lecithin.

2. The composition with moisturizing effect according to claim 1, characterized in that, In the composition with moisturizing effect, the mass ratio of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract is 1:10:1:

1.

3. A method for preparing the composition with moisturizing effect according to claim 1 or 2, characterized in that, Includes the following steps: Step S1: Homogenize soybean lecithin, giant kelp extract, and red algae extract at high speed until they are evenly dispersed, so that the giant kelp extract and red algae extract are coated with soybean lecithin. Step S2: Add the seed oil of Aldera macrophylla to the substance obtained in step S1 to obtain a composition with moisturizing effect.

4. The method for preparing the composition with moisturizing effect according to claim 3, characterized in that, In step S1, the conditions for high-speed homogenization are: 1-3 atmospheres, temperature 30-65℃, rotation speed 1000-4000 r / min, and time 20-40 min.

5. The use of the moisturizing composition according to claim 1 or 2 in the preparation of cosmetics.

6. A cosmetic product with moisturizing effects, characterized in that, The product includes the moisturizing composition as described in claim 1 or 2, and cosmetic excipients, wherein the moisturizing cosmetic uses the moisturizing composition as an active ingredient, and the moisturizing composition has a mass fraction of 10-50% in the cosmetic.

7. The moisturizing cosmetic according to claim 6, characterized in that, The composition with moisturizing effect has a mass fraction of 10-20% in the cosmetic.

8. A moisturizing serum, characterized in that, Moisturizing serums contain the following components by weight percentage: The mass ratio of soybean lecithin, Aldera macrophylla seed oil, giant kelp extract, and red algae extract is (1-5):(2-10):(1-3):(1-5); the giant kelp extract and red algae extract are encapsulated by soybean lecithin.

9. The moisturizing serum according to claim 8, characterized in that, Moisturizing serums contain the following components by weight percentage:

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