A fully automatic labeling and purification system

Abstract

A fully automatic labeling and purification system provided by the present invention includes a cabinet, a ball washer, an activator, a labeling machine, a sealer, and a storage machine. The ball washer, activator, labeling machine, sealer, and storage machine all include a material transfer mechanism, a transfer robot, and a liquid dispensing station. The ball washer, activator, labeling machine, and sealer also include a centrifugation mechanism and an ultrasonic mechanism. The activator, labeling machine, and sealer also include a mixing mechanism. The material transfer mechanism is used to convey materials. The liquid dispensing station is used to prepare the materials. The centrifugation mechanism is used to centrifuge the prepared liquid. The ultrasonic mechanism is used to ultrasonically crush the prepared liquid. The mixing mechanism is used to shake the prepared liquid evenly. It can automatically complete the processes of material conveyance, material transfer, material preparation, centrifugation, ultrasonic dispersion, and mixing, realizing the automation of the preparation process, reducing the labor input, and making the preparation process simpler and easier.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a fully automatic labeling and purification system. Background Art

[0002] Fluorescent microsphere coating is a preparation process in biopharmaceuticals, which includes five major steps: washing the microspheres, activation, antibody labeling, blocking, and preservation. The washing process includes taking fluorescent microspheres, centrifuging, removing the supernatant and adding a complex solution, and ultrasonic dispersion. The activation process includes adding two activation solutions, mixing, centrifuging, removing the supernatant, adding a complex solution, and ultrasonic dispersion. The labeling process includes adding an antibody, mixing, centrifuging, removing the supernatant, adding a complex solution, and ultrasonic dispersion. The blocking process includes adding a protein solution, mixing, centrifuging, removing the supernatant, adding a complex solution, and ultrasonic dispersion. The preservation process includes adding a blocking solution.

[0003] Since each major step in the preparation of fluorescent microsphere coating also includes multiple small steps, and each step requires some processing time, the total preparation time accumulated for all steps takes several hours. Currently, the preparation process of fluorescent microsphere coating is basically carried out by manually putting materials, manually transferring materials, and manual on-site monitoring. Its operation process is cumbersome, requires a large amount of manpower, and increases the burden on enterprises. Summary of the Invention

[0004] The problem to be solved by the present invention is to provide a fully automatic labeling and purification system, which improves the degree of automation, reduces the input of manpower, and lowers the production cost.

[0005] To solve the above technical problems, a fully automatic labeling and purification system provided by the present invention includes a cabinet. A washing machine, an activation machine, a labeling machine, a blocking machine, and a preservation machine are sequentially arranged on the cabinet. The washing machine, the activation machine, the labeling machine, the blocking machine, and the preservation machine all include a material transfer mechanism, a transfer robot, and a liquid preparation station. The washing machine, the activation machine, the labeling machine, and the blocking machine also include a centrifugation mechanism and an ultrasonic mechanism. The activation machine, the labeling machine, and the blocking machine also include a mixing mechanism. The material transfer mechanism is used to convey materials. The liquid preparation station is used to prepare a preparation liquid by mixing the materials on the material transfer mechanism. The centrifugation mechanism is used to perform centrifugation operations on the preparation liquid. The ultrasonic mechanism is used to perform ultrasonic crushing operations on the preparation liquid. The mixing mechanism is used to shake the preparation liquid evenly. The transfer robot is used to transfer the preparation liquid between adjacent two material transfer mechanisms, and to transfer materials and the preparation liquid between the material transfer mechanism, the liquid preparation station, the ultrasonic mechanism, the centrifugation mechanism, and the mixing mechanism.

[0006] Preferably, the material transfer mechanism includes a first X-axis linear drive device arranged on the cabinet, and a number of material-carrying fixtures drivingly connected to the first X-axis linear drive device. The material-carrying fixtures are used to place large sample bottles and small sample bottles; the liquid preparation station includes a number of positioning mechanisms, liquid storage mechanisms, syringe mechanisms, and liquid transfer mechanisms. The positioning mechanisms are used to position large sample bottles and small sample bottles, the liquid storage mechanisms are used to store reconstitution solution, activation solution, antibody, protein solution, and blocking solution, the syringe mechanisms are used to place syringes, and the liquid transfer mechanisms extract and transfer materials.

[0007] Preferably, the centrifugation mechanism includes a weight balancing mechanism and a centrifuge. The weight balancing mechanism includes two analytical balances.

[0008] Preferably, the ultrasonic mechanism includes a positioning seat for placing small sample bottles, a support frame arranged on the cabinet, a first Z-axis linear drive device arranged on the support frame, and an ultrasonic cell disruptor. The ultrasonic probe of the ultrasonic cell disruptor is drivingly connected to the first Z-axis linear drive device.

[0009] Preferably, the mixing mechanism is an oscillating mixer.

[0010] Preferably, a labeling station is arranged on one side of the preservation machine. The labeling station includes a label printer, a labeling mechanism, and a labeling positioning seat. After the transfer robot places the large sample bottle on the labeling positioning seat for positioning, the labeling mechanism pastes the label output from the label printer on the bottle body of the large sample bottle.

[0011] Preferably, the positioning mechanism includes a first Y-axis linear drive device arranged on the cabinet, and a three-jaw chuck drivingly connected to the first Y-axis linear drive device; the liquid storage mechanism includes a liquid storage box drivingly connected to the first Y-axis linear drive device; the syringe mechanism includes a second Y-axis linear drive device arranged on the cabinet, and a syringe placement fixture drivingly connected to the second Y-axis linear drive device; the liquid transfer mechanism includes a second X-axis linear drive device arranged on the cabinet, and a second Z-axis linear drive device and a third Z-axis linear drive device drivingly connected to the second X-axis linear drive device. A first pipette and a second pipette are respectively drivingly connected to the second Z-axis linear drive device and the third Z-axis linear drive device.

[0012] Preferably, the ultrasonic mechanism further includes a third Y-axis linear drive device arranged on the cabinet, and a cleaning sink drivingly connected to the third Y-axis linear drive device. The positioning seat is drivingly connected to the third Y-axis linear drive device. A clean water storage tank and a waste water storage tank are arranged inside the cabinet. The clean water in the clean water storage tank is supplied to the cleaning sink by an electric pump, and the sewage in the cleaning sink is pumped into the waste water storage tank by an electric pump.

[0013] Preferably, the labeling mechanism includes a fourth Y-axis linear driving device disposed on the cabinet, a fourth Z-axis linear driving device drivingly connected to the fourth Y-axis linear driving device, and a labeling head drivingly connected to the fourth Z-axis linear driving device; the labeling positioning seat includes a support seat disposed on the cabinet, a first roller and a second roller rotatably connected in parallel at the top of the support seat, and a driving motor disposed on the support seat and drivingly connected to the first roller.

[0014] Preferably, a lid placing platform is arranged on one side of the positioning mechanism.

[0015] The beneficial effects of the present invention are as follows: The present invention provides a full-automatic labeling and purification system. The ball washer, activator, labeler, sealer, and storage machine can respectively complete the five steps of washing the balls, activating, labeling antibodies, sealing, and storing during the fluorescence microsphere coating test. By integrating the ball washer, activator, labeler, sealer, and storage machine on one device, the processes of material transportation, material transfer, material preparation, centrifugation, ultrasonic dispersion, and mixing can be automatically completed, realizing the automation of the preparation process, reducing the labor input, and making the preparation process simpler and easier. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 Illustrates the external structure schematic diagram of the left front side view of the present invention.

[0017] Figure 2 Illustrates the external structure schematic diagram of the right front side view of the present invention.

[0018] Figure 3 Illustrates the top view of the present invention.

[0019] Figure 4 Illustrates the rear view of the present invention.

[0020] Figure 5 Illustrates the present invention Figure 1 The partial enlarged structure schematic diagram of part A in it.

[0021] Figure 6 Illustrates the present invention Figure 1 The partial enlarged structure schematic diagram of part B in it.

[0022] Figure 7 Illustrates the present invention Figure 2 The partial enlarged structure schematic diagram of part C in it.

[0023] Explanation of the attached reference numerals: cabinet 10, ball washer 11, activation machine 12, marking machine 13, sealing machine 14, storage machine 15, clean water storage tank 16, waste water storage tank 17, material transfer mechanism 20, first X-axis linear drive device 21, material loading fixture 22, transfer robot 30, liquid preparation station 40, positioning mechanism 41, first Y-axis linear drive device 410, three-jaw chuck 411, lid placing platform 412, liquid storage mechanism 42, liquid storage box 420, syringe mechanism 43, second Y-axis linear drive device 430, syringe placement fixture 431, liquid transfer mechanism 44, second X-axis linear drive device 440, second Z-axis linear drive device 441, third Z-axis linear drive device 442, first liquid transfer pipette 443, second liquid transfer pipette 444, centrifugation mechanism 50, analytical balance 51, centrifuge 52, ultrasonic mechanism 60, positioning seat 61, support frame 62, first Z-axis linear drive device 63, ultrasonic cell disruptor 64, third Y-axis linear drive device 65, cleaning sink 66, mixing mechanism 70, labeling station 80, label printer 81, labeling mechanism 82, fourth Y-axis linear drive device 820, fourth Z-axis linear drive device 821, labeling head 822, labeling positioning seat 83, support seat 830, first roller 831, second roller 832, drive motor 833. Detailed implementation manners

[0024] To make the objectives, technical solutions and advantages of the embodiments of the present disclosure clearer, the technical solutions of the embodiments of the present disclosure will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present disclosure. Apparently, the described embodiments are some but not all of the embodiments of the present disclosure.

[0025] All other embodiments obtained by those of ordinary skill in the art based on the described embodiments of the present disclosure without creative efforts shall fall within the scope of protection of the present disclosure.

[0026] Refer to Figures 1 - 7 。

[0027] The present invention provides a fully automatic labeling and purification system, which includes a cabinet 10. A ball washer 11, an activator 12, a labeling machine 13, a sealer 14, and a storage machine 15 are sequentially arranged on the cabinet 10. The ball washer 11, the activator 12, the labeling machine 13, the sealer 14, and the storage machine 15 all include a material transfer mechanism 20, a transfer robot 30, and a liquid preparation station 40. The ball washer 11, the activator 12, the labeling machine 13, and the sealer 14 also include a centrifugation mechanism 50 and an ultrasonic mechanism 60. The activator 12, the labeling machine 13, and the sealer 14 also include a mixing mechanism 70. The material transfer mechanism 20 is used for conveying materials. The liquid preparation station 40 is used for preparing a prepared liquid by mixing the materials on the material transfer mechanism 20. The centrifugation mechanism 50 is used for centrifuging the prepared liquid. The ultrasonic mechanism 60 is used for ultrasonically pulverizing the prepared liquid. The mixing mechanism 70 is used for shaking the prepared liquid evenly. The transfer robot 30 is used for transferring the prepared liquid between two adjacent material transfer mechanisms 20, and realizing the transfer of materials and the prepared liquid between the material transfer mechanism 20, the liquid preparation station 40, the ultrasonic mechanism 60, the centrifugation mechanism 50, and the mixing mechanism 70.

[0028] Its working principle is as follows: the materials to be prepared are placed on the material transfer mechanism 20 for conveying. The materials on the material transfer mechanism 20 are placed on the liquid preparation station 40 by the transfer robot 30 for material preparation operation. The prepared liquid is placed on the centrifugation mechanism 50 by the transfer robot 30 for centrifugation operation. The prepared liquid is placed on the ultrasonic mechanism 60 by the transfer robot 30 for ultrasonic dispersion operation. The prepared liquid is placed on the mixing mechanism 70 by the transfer robot 30 for oscillating and shaking operation. The materials are transferred between the ball washer 11, the activator 12, the labeling machine 13, the sealer 14, and the storage machine 15 by the transfer robot 30. By integrating the ball washer, the activator, the labeling machine, the sealer, and the storage machine into one device, the processes of material conveying, material transfer, material preparation, centrifugation, ultrasonic dispersion, and mixing can be automatically completed. The five steps of ball washing, activation, antibody labeling, sealing, and storage in the fluorescence microsphere coating test process can be completed, realizing the automation of the preparation process, reducing the labor input, and making the preparation process simpler and easier.

[0029] Based on the above embodiments, the material transfer mechanism 20 includes a first X-axis linear driving device 21 disposed on the cabinet 10 and a number of loading fixtures 22 drivingly connected to the first X-axis linear driving device 21. The loading fixtures 22 are used to place large sample bottles and small sample bottles. The liquid dispensing station 40 includes a number of positioning mechanisms 41, a liquid storage mechanism 42, a syringe mechanism 43, and a liquid transfer mechanism 44. The positioning mechanism 41 is used to position the large sample bottles and small sample bottles. The liquid storage mechanism 42 is used to store the reconstitution solution, activation solution, antibody, protein solution, and blocking solution. The syringe mechanism 43 is used to place syringes. The liquid transfer mechanism 44 extracts and transfers materials. Specifically, manually place the large sample bottle filled with the fluorescent microsphere stock solution on the loading fixture 22 on the side of the bead washer 11, and place an empty small sample bottle for liquid dispensing on the loading fixture 22. The first X-axis linear driving device 21 can drive the loading fixture 22 to move left and right, thereby driving the large sample bottle and the small sample bottle to be conveyed forward. The reconstitution solution, activation solution, antibody, and protein solution are prepared in advance on the liquid storage mechanism 42. The transfer robot 30 places the large sample bottle and the small sample bottle on the positioning mechanism 41 for positioning and unscrews and places the bottle caps. The liquid transfer mechanism 44 can load syringes at the syringe mechanism 43 by itself. A new syringe needs to be replaced for each extraction of different liquids. The liquid transfer mechanism 44 can distribute the fluorescent microspheres in the large sample bottle into the small sample bottle, and can suck the reconstitution solution, activation solution, antibody, and protein solution at the liquid storage mechanism 42 and add them to the small sample bottle, and can perform the operation of removing the supernatant from the prepared liquid. After each major step is completed, the transfer robot 30 transfers the prepared small sample bottle to the loading fixture 22 of the material transfer mechanism 20 in the next step. The large sample bottle is emptied and also transferred to the loading fixture 22 of the material transfer mechanism 20 in the next step, which is convenient for using the empty large sample bottle at the storage machine 15 to refill the finally prepared product into the large sample bottle for packing.

[0030] Based on the above embodiments, the centrifugation mechanism 50 includes a weight balancing mechanism and a centrifuge 52. The weight balancing mechanism includes two analytical balances 51. Specifically, the centrifuge 52 has two symmetrically arranged material trays. The weights on both sides of the material trays need to be the same to perform rotational centrifugation. During the centrifugation operation, the transfer robot 30 places the small sample bottle filled with the prepared liquid on the analytical balance 51 and makes the weights of the small sample bottles placed on the two analytical balances 51 the same. When there is a difference in weight between the two analytical balances 51, the liquid transfer mechanism 44 takes out an appropriate amount of the prepared liquid from the small sample bottle on the heavier analytical balance 51 to make the weights on the two analytical balances 51 the same. Then, the transfer robot 30 takes the small sample bottles on the two analytical balances 51 and places them on the two material trays of the centrifuge 52 respectively, and then the centrifuge 52 performs the centrifugation operation on the prepared liquid in the small sample bottles.

[0031] Based on the above embodiments, the ultrasonic mechanism 60 includes a positioning seat 61 for placing small sample bottles, a support frame 62 provided on the cabinet 10, a first Z-axis linear driving device 63 provided on the support frame 62, and an ultrasonic cell disruptor 64. The ultrasonic probe of the ultrasonic cell disruptor 64 is drivingly connected to the first Z-axis linear driving device 63. Specifically, during the ultrasonic dispersion operation, the transfer robot 30 picks up the small sample bottle filled with the preparation liquid and places it on the positioning seat 61 for positioning. After the bottle mouth of the small sample bottle is unscrewed and aligned with the ultrasonic probe of the ultrasonic cell disruptor 64, the first Z-axis linear driving device 63 drives the ultrasonic probe of the ultrasonic cell disruptor 64 to extend into the liquid in the small sample bottle to perform ultrasonic dispersion operation on the preparation liquid.

[0032] Based on the above embodiments, the mixing mechanism 70 is an oscillating mixer. A tray for placing small sample bottles is arranged on the oscillating mixer. The transfer robot 30 picks up the small sample bottle and places it on the tray of the oscillating mixer. When the oscillating mixer works, it drives the preparation liquid in the small sample bottle to oscillate, so as to achieve the effect of shaking the preparation liquid evenly.

[0033] Based on the above embodiments, a labeling station 80 is provided on one side of the storage machine 15. The labeling station 80 includes a label printer 81, a labeling mechanism 82, and a labeling positioning seat 83. After the transfer robot 30 places the large sample bottle on the labeling positioning seat 83 for positioning, the labeling mechanism 82 pastes the label output from the label printer 81 onto the bottle body of the large sample bottle. Specifically, after the preparation liquid in the small sample bottle completes the final preparation operation, the liquid transfer mechanism 44 reinstalls the preparation liquid in the small sample bottle back into an empty large sample bottle. The transfer robot 30 picks up the large sample bottle filled with the preparation liquid and places it on the labeling positioning seat 83 for positioning. The label printer 81 prints out a label paper, and the labeling mechanism 82 pastes the printed label paper onto the bottle body of the large sample bottle to complete the preparation of the product.

[0034] Based on the above embodiments, the positioning mechanism 41 includes a first Y-axis linear driving device 410 disposed on the cabinet 10, and a three-jaw chuck 411 drivingly connected to the first Y-axis linear driving device 410; the liquid storage mechanism 42 includes a liquid storage box 420 drivingly connected to the first Y-axis linear driving device 410; the syringe mechanism 43 includes a second Y-axis linear driving device 430 disposed on the cabinet 10, and a syringe placement jig 431 drivingly connected to the second Y-axis linear driving device 430; the liquid transfer mechanism 44 includes a second X-axis linear driving device 440 disposed on the cabinet 10, a second Z-axis linear driving device 441 and a third Z-axis linear driving device 442 drivingly connected to the second X-axis linear driving device 440, and a first pipette 443 and a second pipette 444 are respectively drivingly connected to the second Z-axis linear driving device 441 and the third Z-axis linear driving device 442. Specifically, a plurality of liquid storage cells are provided on the liquid storage box 420 of the liquid storage mechanism 42, and different liquids are stored in each liquid storage cell. Complex solution, activation solution, antibody, protein solution, etc. can be stored according to the usage needs. The first Y-axis linear driving device 410 can drive the three-jaw chuck 411 and the liquid storage box 420 to move between the transfer robot 30 and the liquid transfer mechanism 44, so as to facilitate the transfer robot 30 to place the large sample bottle and the small sample bottle on the three-jaw chuck 411 for positioning; the second Y-axis linear driving device 430 can drive the syringe placement jig 431 to move back and forth, and syringes are placed on the syringe placement jig 431, which facilitates the transfer robot 30 to load syringes from the syringe placement jig 431; the second X-axis linear driving device 440 can drive the first pipette 443 and the second pipette 444 to move left and right, and the second Z-axis linear driving device 441 and the third Z-axis linear driving device 442 can respectively drive the first pipette 443 and the second pipette 444 to move up and down, which facilitates the liquid transfer mechanism 44 to extract the liquid in the liquid storage box 420 from the liquid storage box 420 and add the liquid to the small sample bottle. The first pipette 443 and the second pipette 444 are respectively a low-precision pipette and a high-precision pipette. The first pipette 443 is suitable for extracting a relatively large amount of liquid at one time, and the second pipette 444 is suitable for extracting a relatively small amount of liquid at one time.

[0035] Based on the above embodiments, the ultrasonic mechanism 60 further includes a third Y-axis linear driving device 65 disposed on the cabinet 10, a cleaning water tank 66 drivingly connected to the third Y-axis linear driving device 65, and a positioning seat 61 drivingly connected to the third Y-axis linear driving device 65. A fresh water storage tank 16 and a waste water storage tank 17 are arranged inside the cabinet 10. The fresh water in the fresh water storage tank 16 is supplied to the cleaning water tank 66 by an electric pump, and the sewage in the cleaning water tank 66 is pumped into the waste water storage tank 17 by an electric pump. Specifically, the third Y-axis linear driving device 65 can drive the cleaning water tank 66 and the positioning seat 61 to move back and forth. When ultrasonic dispersion is required, the third Y-axis linear driving device 65 is used to drive the positioning seat 61 to move so that the mouth of the small sample bottle on the positioning seat 61 is located below the ultrasonic probe of the ultrasonic cell crusher 64. The ultrasonic probe of the ultrasonic cell crusher 64 is driven by the first Z-axis linear driving device 63 to extend into the preparation liquid in the small sample bottle for ultrasonic dispersion. Then, the ultrasonic probe of the ultrasonic cell crusher 64 is driven by the first Z-axis linear driving device 63 to rise and reset. The third Y-axis linear driving device 65 is used to drive the cleaning water tank 66 to move so that the cleaning water tank 66 is aligned with the ultrasonic probe of the ultrasonic cell crusher 64. Then, the ultrasonic probe of the ultrasonic cell crusher 64 is driven by the first Z-axis linear driving device 63 to extend into the cleaning water tank 66, and the cleaning water in the fresh water storage tank 16 is pumped into the cleaning water tank 66 by an electric pump to wash the ultrasonic probe. At the same time, the sewage in the cleaning water tank 66 is pumped into the waste water storage tank 17 for storage by an electric pump to prevent cross-contamination when the ultrasonic probe performs ultrasonic dispersion on the preparation liquids in different small sample bottles.

[0036] Based on the above embodiments, the labeling mechanism 82 includes a fourth Y-axis linear driving device 820 disposed on the cabinet 10, a fourth Z-axis linear driving device 821 drivingly connected to the fourth Y-axis linear driving device 820, and a labeling head 822 drivingly connected to the fourth Z-axis linear driving device 821; the labeling positioning seat 83 includes a support seat 830 disposed on the cabinet 10, a first roller 831 and a second roller 832 rotatably connected in parallel at the top of the support seat 830, and a driving motor 833 disposed on the support seat 830 and drivingly connected to the first roller 831. Specifically, after the preparation liquid in the small sample bottle at the storage machine 15 is filled back into the large sample bottle, the transfer robot 30 horizontally places the large sample bottle between the tops of the first roller 831 and the second roller 832. The driving motor 833 drives the first roller 831 to rotate, thereby driving the large sample bottle to rotate between the tops of the first roller 831 and the second roller 832. After the label printer prints out the label, the fourth Y-axis linear driving device 820 can drive the labeling head 822 to move back and forth, and the fourth Z-axis linear driving device 821 can drive the labeling head 822 to move up and down. The labeling head 822 has an adsorption function, and can allow the labeling head 822 to absorb the label and paste it on the body of the large sample bottle.

[0037] Based on the above embodiments, a cap placing platform 412 is provided on one side of the positioning mechanism 41. After the transfer robot 30 unscrews the caps of the large sample bottles and small sample bottles, the caps can be placed on the cap placing platform 412.

[0038] The above embodiments are only descriptions of the preferred embodiments of the present invention and do not limit the scope of the present invention. Without departing from the design spirit of the present invention, various deformations and improvements made by those of ordinary skill in the art to the technical solutions of the present invention shall fall within the protection scope determined by the claims of the present invention.

Claims

1. A fully automatic labeling and purification system, comprising a cabinet, characterized in that, a ball washer, an activator, a marker, a sealer, and a storage machine are sequentially arranged on the cabinet. The ball washer, activator, marker, sealer, and storage machine all include a material transfer mechanism, a transfer robot, and a liquid dispensing station. The ball washer, activator, marker, and sealer also include a centrifugation mechanism and an ultrasonic mechanism. The activator, marker, and sealer also include a mixing mechanism. The material transfer mechanism is used for conveying materials. The material transfer mechanism includes a first X-axis linear driving device arranged on the cabinet and a plurality of loading fixtures drivingly connected to the first X-axis linear driving device. The loading fixtures are used for placing large sample bottles and small sample bottles. The liquid dispensing station is used for dispensing the materials on the material transfer mechanism to generate a dispensing liquid. The liquid dispensing station includes a plurality of positioning mechanisms, a liquid storage mechanism, a syringe mechanism, and a liquid transfer mechanism. The positioning mechanism is used for positioning the large sample bottles and small sample bottles. The liquid storage mechanism is used for storing a complex solution, an activation solution, an antibody, a protein solution, and a sealing solution. The syringe mechanism is used for placing syringes. The liquid transfer mechanism extracts and transfers the materials. The centrifugation mechanism is used for centrifuging the dispensing liquid. The ultrasonic mechanism is used for ultrasonically pulverizing the dispensing liquid. The mixing mechanism is used for shaking the dispensing liquid evenly. The transfer robot is used for transferring the dispensing liquid between two adjacent material transfer mechanisms and realizing the transfer of materials and dispensing liquid between the material transfer mechanism, the liquid dispensing station, the ultrasonic mechanism, the centrifugation mechanism, and the mixing mechanism.

2. A fully automatic labeling and purification system according to claim 1, characterized in that, the centrifugation mechanism includes a counterweight mechanism and a centrifuge, and the counterweight mechanism includes two analytical balances.

3. A fully automatic labeling and purification system according to claim 2, characterized in that, the ultrasonic mechanism includes a positioning seat for placing small sample bottles, a support frame arranged on the cabinet, a first Z-axis linear driving device arranged on the support frame, and an ultrasonic cell crusher. The ultrasonic probe of the ultrasonic cell crusher is drivingly connected to the first Z-axis linear driving device.

4. A fully automatic labeling and purification system according to claim 3, characterized in that, the mixing mechanism is an oscillating mixer.

5. A fully automatic labeling and purification system according to claim 4, characterized in that, a labeling station is arranged on one side of the storage machine. The labeling station includes a label printer, a labeling mechanism, and a labeling positioning seat. After the transfer robot places the large sample bottle on the labeling positioning seat for positioning, the labeling mechanism pastes the label output from the label printer on the bottle body of the large sample bottle.

6. A fully automatic labeling and purification system according to claim 5, characterized in that, The positioning mechanism includes a first Y-axis linear driving device disposed on the cabinet, and a three-jaw chuck drivingly connected to the first Y-axis linear driving device; the liquid storage mechanism includes a liquid storage box drivingly connected to the first Y-axis linear driving device; the syringe mechanism includes a second Y-axis linear driving device disposed on the cabinet, and a syringe placement jig drivingly connected to the second Y-axis linear driving device; the liquid transfer mechanism includes a second X-axis linear driving device disposed on the cabinet, a second Z-axis linear driving device and a third Z-axis linear driving device drivingly connected to the second X-axis linear driving device, and a first liquid transfer gun and a second liquid transfer gun are respectively drivingly connected to the second Z-axis linear driving device and the third Z-axis linear driving device.

7. A full-automatic labeling and purification system according to claim 6, wherein, the ultrasonic mechanism further includes a third Y-axis linear driving device disposed on the cabinet, a cleaning water tank drivingly connected to the third Y-axis linear driving device, the positioning seat is drivingly connected to the third Y-axis linear driving device, a fresh water storage tank and a waste water storage tank are disposed inside the cabinet, fresh water in the fresh water storage tank is supplied to the cleaning water tank by an electric pump, and sewage in the cleaning water tank is pumped into the waste water storage tank by an electric pump.

8. A full-automatic labeling and purification system according to claim 7, wherein, the labeling mechanism includes a fourth Y-axis linear driving device disposed on the cabinet, a fourth Z-axis linear driving device drivingly connected to the fourth Y-axis linear driving device, and a labeling head drivingly connected to the fourth Z-axis linear driving device; the labeling positioning seat includes a support seat disposed on the cabinet, a first roller and a second roller rotatably connected in parallel at the top of the support seat, and a driving motor disposed on the support seat and drivingly connected to the first roller.

9. A full-automatic labeling and purification system according to claim 8, wherein, a cover placing platform is disposed on one side of the positioning mechanism.

Images