Microinjection device

Abstract

The application discloses a micro-injection device, which comprises a shell and a liquid suction push rod penetrating through the shell, one end of the liquid suction push rod is located outside the shell, the other end is provided with a clamping piece for fixing an injection needle, a liquid suction assembly is further arranged in the shell, the liquid suction assembly comprises a first gear for driving the liquid suction push rod, the first gear is further connected with a zero setting part located outside the shell, a first gear rack is arranged on the rod body of the liquid suction push rod, the first gear rack is connected with the first gear through a first secondary gear meshing with the first gear rack, the zero setting part is a zero setting gear, the zero setting gear is connected with the first gear through a connecting rod, and a rotatable scale disc is arranged on the zero setting gear in a sleeving mode along the circumference of the zero setting gear. The injection needle can be conveniently clamped and fixed, the liquid suction push rod cooperates with the first gear and the zero setting part to realize accurate and quantitative liquid suction and quantitative injection, and the operation is convenient.

Description

Technical Field

[0001] This invention belongs to the field of microinjection technology, and particularly relates to a microinjection device. Background Technology

[0002] Syringes are a common medical device. In daily medical life, syringes can quickly deliver drugs to various parts of the body through blood circulation. However, in medical experiments, microinjection devices, such as microinjection needles, are often used when injecting embryos. Most microinjection devices inject liquids by blowing air. Although the structure is simple, it is difficult to achieve accurate quantitative injection. In order to achieve accurate quantitative injection, more complex pneumatic electronic devices are often used on the market. These devices are not only complicated to operate, but also very expensive. Although they can meet a certain injection accuracy, they still cannot achieve precise quantitative aspiration and injection. Summary of the Invention

[0003] The purpose of this invention is to overcome the shortcomings of the prior art by providing a microinjection device that utilizes a mechanical structure to achieve precise quantitative liquid aspiration.

[0004] The objective of this invention is achieved through the following technical solution:

[0005] A microinjection device includes a housing and a liquid-absorbing push rod penetrating the housing. One end of the liquid-absorbing push rod is located outside the housing, and the other end is provided with a clamping member for fixing an injection needle. The housing also contains a liquid-absorbing assembly, which includes a first gear for driving the liquid-absorbing push rod. The first gear is also connected to an adjusting part located outside the housing.

[0006] In one embodiment, a first rack is provided on the rod body of the liquid suction push rod. The first rack is connected to the first gear through a first set of teeth meshing with it. The adjusting part is a zero-adjustment gear. The zero-adjustment gear is connected to the first gear through a connecting rod. A rotatable scale is sleeved on the zero-adjustment gear along its circumference.

[0007] In one embodiment, the clamping member can penetrate the housing and has a hollow horn structure, and the clamping member is composed of at least two clamping parts.

[0008] In one embodiment, the system further includes an injection assembly comprising an injection pusher extending through the housing, one end of which is located outside the housing and the other end is located inside the housing and connected to a second gear that meshes with the first gear.

[0009] In one embodiment, the injection push rod is provided with a second rack, which is connected to the second gear through a second auxiliary tooth meshing with it, and the second auxiliary tooth is connected to the second gear through a movable gear set.

[0010] In one embodiment, the second gear is a ratchet, the movable gear set includes a sliding plate, the sliding plate is disposed on a slide rail inside the housing, the sliding plate is located above the ratchet, and the sliding plate is provided with parallel movable teeth and a third rack, the third rack meshes with the second auxiliary teeth, and the movable teeth correspond to the ratchet.

[0011] In one embodiment, a movable toothed disc is also mounted on the housing, the movable toothed disc is marked with an injection scale, a fixing member capable of fixing the movable toothed disc is installed next to the movable toothed disc, a pointer located outside the housing is connected to the center of the second auxiliary tooth, and a locking pin capable of blocking the pointer is also provided on the movable toothed disc.

[0012] In one embodiment, a reset spring is further provided within the housing, and one end of the injection plunger located within the housing is connected to both the reset spring and the movable plate.

[0013] In one embodiment, the end of the injection plunger is provided with a pulley, the pulley is connected to the reset spring, and the pulley is connected to the movable plate via a conveyor belt.

[0014] In one embodiment, the housing is a handheld polyhedral structure.

[0015] The beneficial effects of this invention are as follows:

[0016] (1) It is easy to clamp and fix the injection needle, and at the same time, the liquid aspiration push rod, together with the first gear and the adjusting parts, can achieve precise quantitative liquid aspiration;

[0017] (2) By using the injection push rod in conjunction with the ratchet device and the movable toothed disc, a single precise injection of liquid can be achieved. Furthermore, the spring reset ensures that the push rod returns to its original position after reset, which facilitates the rapid completion of multiple injections of the same dose.

[0018] (3) When operating this device, parameters are adjusted by multiple sets of knobs. After the parameters are set, precise injection can be completed simply by pushing the push rod.

[0019] (4) The mechanical structure completes a series of processes from fixing the micro-injection needle, liquid aspiration and precise injection, which optimizes the quantitative inaccuracy of the mouth-blowing method and gets rid of the constraints of the pneumatic motor. Attached Figure Description

[0020] The invention will now be described in more detail with reference to embodiments and the accompanying drawings.

[0021] Figure 1 This shows a schematic diagram of the structure of the present invention in one direction;

[0022] Figure 2 A schematic diagram of the invention in another direction is shown;

[0023] In the accompanying drawings, the same parts use the same reference numerals. The drawings are not to scale.

[0024] Figure label:

[0025] 1-Housing, 2-Liquid suction push rod, 3-Clamping component, 4-First gear, 5-Adjusting component, 6-First rack, 7-First auxiliary gear, 8-Connecting rod, 9-Digital dial, 10-Injection push rod, 11-Second gear, 12-Second rack, 13-Second auxiliary gear, 14-Sliding plate, 15-Modible gear, 16-Third rack, 17-Modible gear disc, 18-Fixing component, 19-Pointer, 20-Clamping pin, 21-Reset spring, 22-Pulley, 23-Conveyor belt. Detailed Implementation

[0026] The invention will now be further described with reference to the accompanying drawings.

[0027] This invention provides a microinjection device, such as... Figure 1 and Figure 2 As shown, it includes a housing 1 and a liquid suction push rod 2 that penetrates the housing 1. One end of the liquid suction push rod 2 is located outside the housing 1, and the other end is provided with a clamping member 3 for fixing the injection needle. The housing 1 is also provided with a liquid suction assembly, which includes a first gear 4 that drives the liquid suction push rod 2. The first gear 4 is also connected to an adjusting part 5 located outside the housing 1.

[0028] Specifically, a first rack 6 is provided on the rod body of the liquid suction push rod 2. The first rack 6 is connected to the first gear 4 through a first auxiliary tooth 7 that meshes with it. The adjusting part 5 is a zero-adjustment gear. The zero-adjustment gear is connected to the first gear 4 through a connecting rod 8. A rotatable scale 9 is sleeved on the zero-adjustment gear along its circumference.

[0029] It should be noted that the injection needle is fixed by the clamp 3. After fixing the injection needle, the zero adjustment gear is adjusted so that the front end of the liquid dispensing push rod is located at the tip of the injection needle. The recording scale is adjusted, and the zero adjustment gear is rotated in the opposite direction to draw liquid in a quantitative manner as needed.

[0030] Furthermore, the clamping member 3 can penetrate the housing 1, and the clamping member 3 has a hollow horn structure. The clamping member 3 is composed of at least two clamping parts. That is, by using the liquid suction push rod 2 to push the clamping member 3, multiple clamping parts open, the gap in the middle increases, and the micro-injection needle can be inserted. Then, the liquid suction push rod 2 is released. During the process of the liquid suction push rod 2 retracting, the gap between multiple clamping parts contracts, which can fix the injection needle. The scale 9 is in a movable state when zeroing. When the liquid suction push rod 2 is pushed to the maximum extent, the zero mark on the scale 9 is aligned with the scale line of the device to achieve zeroing. Then, the zeroing gear is rotated in the opposite direction to quantitatively draw liquid.

[0031] In one embodiment, such as Figure 1 and Figure 2 As shown, it also includes an injection assembly, which includes an injection push rod 10 that penetrates the housing 1. One end of the injection push rod 10 is located outside the housing 1, and the other end is located inside the housing 1 and connected to a second gear 11 that meshes with the first gear 4. That is, after liquid aspiration is completed, the second gear 11 can be rotated by pushing the injection push rod 10, which in turn drives the first gear 4 that meshes with it. Thus, the first gear 4 can be controlled by manipulating the injection push rod 10 to complete the injection.

[0032] Furthermore, such as Figure 1 and Figure 2 As shown, the injection push rod 10 is provided with a second rack 12. The second rack 12 is connected to the second gear 11 through a second auxiliary tooth 13 that meshes with it. The second auxiliary tooth 13 is connected to the second gear 11 through a set of movable teeth 15. The second gear 11 is a ratchet. The set of movable teeth 15 includes a sliding plate 14. The sliding plate 14 is disposed on a slide rail inside the housing 1. The sliding plate 14 is located above the ratchet. The sliding plate 14 is provided with parallel movable teeth 15 and a third rack 16. The third rack 16 meshes with the second auxiliary tooth 13. The movable teeth 15 correspond to the ratchet.

[0033] It should be noted that a second rack 12 is provided on the injection push rod 10, and the second rack 12 meshes with the second auxiliary gear 13. That is, when the injection push rod 10 is pushed, the second auxiliary gear 13 can be driven to rotate. During the rotation of the second auxiliary gear 13, the third rack 16 located above and meshing with the second auxiliary gear 13 also moves, that is, it drives the sliding plate 14 to move along the slide rail of the housing 1. The movable tooth 15, which is arranged parallel to the third rack 16, is arranged on the sliding plate 14. As the sliding plate 14 moves, since the second gear 11 is a ratchet, when the injection push rod 10 moves into the housing 1, the movable tooth 15 can drive the ratchet to rotate. When the ratchet rotates, it drives the first gear 4 meshing with it to rotate, and then drives the liquid suction push rod 2 to move towards the injection needle through the first auxiliary gear 7, thereby completing the injection operation. When the injection push rod 10 gradually moves away from the housing 1, the movable tooth 15 also moves with the sliding plate 14, but cannot drive the ratchet to rotate.

[0034] Furthermore, such as Figure 1 and Figure 2 As shown, a movable toothed disc 17 is also installed on the housing 1. The movable toothed disc 17 is marked with an injection scale. A fixing member 18 that can fix the movable toothed disc 17 is installed next to the movable toothed disc 17. The center of the second auxiliary tooth 13 is connected to a pointer 19 located outside the housing 1. A locking pin 20 that can block the pointer 19 is also provided on the movable toothed disc 17.

[0035] It should be noted that the movable toothed disc 17 mounted on the housing 1 does not mesh with other components. It has evenly divided injection graduations along its circumference. A pointer 19 located outside the housing 1 is connected to the center of the second auxiliary tooth 13. The pointer 19 passes through the movable toothed disc 17, meaning that as the second auxiliary tooth 13 rotates, the pointer 19 also rotates with it. A retaining pin 20 is mounted on the movable toothed disc 17, and a fixing member 18 is also provided beside it. This allows for adjustment of the angle between the retaining pin 20 and the pointer 19 during injection, according to the needs of a single injection. After adjustment, the fixing member 18 secures the movable toothed disc 17, thereby pushing the injection pusher 1. At 0 o'clock, the second set of teeth 13 rotates, driving the pointer 19 to rotate. When the pointer 19 rotates to the clasp 20, it is blocked by the clasp 20. The operator can also receive feedback at the same time, and can know that a quantitative injection has been completed. In the field of microinjection, the injection operation is very troublesome. If the mouth blowing method is used, although the operation is relatively simple, it is difficult to control the injection volume accurately, which is difficult to meet the application scenarios such as experimental comparison. Pneumatic electronic instruments are not only expensive, but their operation is also relatively troublesome. After completing the quantitative liquid aspiration, the required injection volume is adjusted before injection, and a quantitative injection can be completed by pushing the injection push rod 10, which is very convenient and improves injection efficiency.

[0036] Specifically, such as Figure 1 As shown, the fixing member 18 has a caliper structure and is mounted on the housing 1. The two ends of the fixing member 18 are fitted with the gap between two adjacent teeth in the movable toothed disc 17, which ensures accurate quantitative injection.

[0037] In one embodiment, it further includes a reset spring 21 disposed in the housing 1, one end of the injection push rod 10 located in the housing 1 is connected to the reset spring 21 and the movable plate respectively, and the end of the injection push rod 10 is provided with a pulley 22, which is connected to the reset spring 21 and the pulley 22 is connected to the movable plate through the conveyor belt 23.

[0038] Specifically, such as Figure 1 and Figure 2As shown, the front end of the injection push rod 10 is provided with a pulley 22, which is connected to the reset spring 21. When the injection push rod 10 is pushed forward, the reset spring 21 separates and generates elastic force. At the same time, there is also a similar reset spring 21 on its side that generates elastic force. That is, after the injection push rod 10 is released, the reset spring 21 pushes the pulley 22 backward. During the pushing process, the transmission belt connected to the injection push rod 10 also drives the sliding plate 14 to return. At this time, the movable tooth 15 moves with the sliding plate 14, but cannot drive the ratchet to rotate.

[0039] It should be noted that the reset spring 21 is made of a rigid spring. The reset spring 21 pushes the injection plunger 10, causing the injection plunger 10 to return to its pre-injection position. During this process, the pointer 19 connected to the second auxiliary tooth 13 also rotates back to its initial position. That is, when conducting experiments such as mouse experiments, since it is necessary to control the target substance during injection, the operator only needs to press the injection plunger 10 multiple times to complete multiple quantitative injections. This is very convenient and quick for microinjection experiments.

[0040] In one embodiment, such as Figure 1 and Figure 2 As shown, the housing 1 has a handheld polyhedral structure for easy gripping.

[0041] In the description of this invention, it should be understood that the terms "upper", "lower", "bottom", "top", "front", "rear", "inner", "outer", "left", "right", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0042] While the invention has been described herein with reference to specific embodiments, it should be understood that these embodiments are merely examples of the principles and applications of the invention. Therefore, it should be understood that many modifications can be made to the exemplary embodiments, and other arrangements can be designed without departing from the spirit and scope of the invention as defined by the appended claims. It should be understood that different dependent claims and features described herein can be combined in ways different from those described in the original claims. It is also understood that features described in conjunction with individual embodiments can be used in other described embodiments.

Claims

1. A microinjection device, characterized in that, The device includes a housing and a liquid-absorbing push rod that penetrates the housing. One end of the liquid-absorbing push rod is located outside the housing, and the other end is provided with a clamping member for fixing an injection needle. The housing also contains a liquid-absorbing assembly, which includes a first gear that drives the liquid-absorbing push rod. The first gear is also connected to an adjusting part located outside the housing. It also includes an injection assembly, which includes an injection push rod that passes through the housing, one end of which is located outside the housing and the other end is located inside the housing and connected to a second gear that meshes with the first gear; The injection push rod is provided with a second rack, which is connected to the second gear through a second auxiliary tooth meshing with it. The second auxiliary tooth is connected to the second gear through a movable gear set. The second gear is a ratchet, and the movable gear set includes a sliding plate. The sliding plate is disposed on a slide rail inside the housing. The sliding plate is located above the ratchet, and the sliding plate is provided with parallel movable teeth and a third rack. The third rack meshes with the second auxiliary teeth, and the movable teeth correspond to the ratchet.

2. The microinjection device according to claim 1, characterized in that, The liquid suction push rod is provided with a first rack, which is connected to the first gear through a first set of teeth meshing with it. The adjusting part is a zero-adjustment gear, which is connected to the first gear through a connecting rod. A rotatable scale is fitted on the zero-adjustment gear along its circumference.

3. The microinjection device according to claim 1, characterized in that, The clamping member can penetrate the housing and has a hollow horn structure. The clamping member is composed of at least two clamping parts.

4. The microinjection device according to claim 1, characterized in that, The housing is also equipped with a movable toothed disc, which is marked with injection scale. A fixing member capable of fixing the movable toothed disc is installed next to it. The center of the second auxiliary tooth is connected to a pointer located outside the housing, and the movable toothed disc is also equipped with a locking pin capable of blocking the pointer.

5. A microinjection device according to claim 1, characterized in that, It also includes a reset spring disposed within the housing, and one end of the injection plunger located within the housing is connected to the reset spring and the movable plate, respectively.

6. A microinjection device according to claim 5, characterized in that, The injection plunger is equipped with a pulley at its end, the pulley is connected to the reset spring, and the pulley is connected to the movable plate via a conveyor belt.

7. A microinjection device according to claim 1, characterized in that, The shell is a handheld polyhedral structure.

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