Pipette and operating table
Through the dual pipette design, the problem of droplets being unable to drip or backflow is solved, ensuring that the droplets entering the detector smoothly, improving the accuracy and reliability of the detection.
Patent Information
- Application Number
- CN202310261432.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-03-17
- Publication Date
- 2025-08-26
- Estimated Expiration
- 2043-03-17
AI Technical Summary
When the existing pipette drops to be detected into the detector, there is a possibility that the droplets cannot be dripped or flow backwards after dripping, resulting in inaccurate detection.
The double pipette design is adopted. The first pipette is used to inject and measure droplets, and the second pipette is used to suck out the same volume of filling liquid, reducing the pressure in the detector, ensuring the smooth entry of the droplets and reducing backflow.
The accurate droplet in and reduction of backflow of the droplets to be detected is achieved, and the reliability and accuracy of the detection is improved.
Smart Images

Figure CN116351493B_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of laboratory instruments, and in particular to a pipette and an operating table. Background Art
[0002] When performing biological, chemical, or medical analysis on a droplet to be tested, the droplet needs to be dropped into the filling liquid in the detector. However, when using current pipettes to drop the droplet to be tested into the filling liquid, there is a possibility that the droplet to be tested cannot be dropped into the filling liquid, or that the droplet to be tested may flow back after being injected into the filling liquid. Summary of the Invention
[0003] The present application provides a pipette and an operating table for solving the problem that a droplet to be detected cannot drip into a detector or flows back after dripping.
[0004] In a first aspect, an embodiment of the present application provides a pipette, comprising:
[0005] a pipetting assembly for injecting a measuring liquid droplet into a detector;
[0006] A control component, connected to the pipetting component and used to drive the pipetting component to move;
[0007] In which, the pipetting assembly includes a first pipette and a second pipette, both of which can be extended into the detector, the first pipette is used to inject the measurement droplet into the detector, and the second pipette is used to suck out the filling liquid in the detector, and the volume of the measurement droplet injected by the first pipette is consistent with the volume of the filling liquid sucked out by the second pipette.
[0008] In the second aspect, an embodiment of the present application also provides an operating table, which includes a carrying platform and a support member, wherein the support member is connected to the carrying platform, the carrying platform is used to carry a detector, and a pipette can pass through the support member and extend into the detector, and the pipette is the pipette described above.
[0009] A first pipette and a second pipette are provided in the pipette. The first pipette and the second pipette can be extended into the detector at the same time. While the measuring liquid droplets in the first pipette are dripped into the detector, the second pipette can suck out the same volume of filling liquid, thereby reducing the pressure in the detector and allowing the droplets to enter the detector smoothly. At the same time, the possibility of the measuring liquid droplets flowing back can be reduced.
[0010] It should be understood that the foregoing general description and the following detailed description are merely illustrative and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS
[0011] Figure 1A schematic diagram of the structure of the pipette and operating table provided in an embodiment of the present application;
[0012] Figure 2 A schematic diagram of the structure of the pipetting assembly and detector provided in an embodiment of the present application;
[0013] Figure 3 A schematic diagram of the structure of the control component provided in an embodiment of the present application;
[0014] Figure 4 for Figure 3 Cross-sectional view in the AA direction;
[0015] Figure 5 A schematic diagram of the structure of a display assembly provided in an embodiment of the present application;
[0016] Figure 6 for Figure 5 Cross-sectional view in the middle BB direction;
[0017] Figure 7 for Figure 5 Cross-sectional view in CC direction;
[0018] Figure 8 for Figure 5 Cross-sectional view in the middle DD direction;
[0019] Figure 9 A schematic diagram of the structure of the operating console provided in an embodiment of the present application.
[0020] Reference numerals:
[0021] 1-Pipette assembly;
[0022] 11- first pipette;
[0023] 111-first cavity;
[0024] 112 - first piston;
[0025] 12- Second pipette;
[0026] 121- second cavity;
[0027] 122 - second piston;
[0028] 13-Connection block;
[0029] 2- detector;
[0030] 21-Measurement droplet;
[0031] 22-filling fluid;
[0032] 23-hydrophobic layer;
[0033] 24-electrode;
[0034] 25-upper base plate;
[0035] 26-lower base plate;
[0036] 27- injection hole;
[0037] 28-suction hole;
[0038] 29-plastic frame;
[0039] 3- Control components;
[0040] 31- housing;
[0041] 311- raised portion;
[0042] 32- driving member;
[0043] 321- positioning protrusion;
[0044] 322-depression;
[0045] 33- ejector rod;
[0046] 34- moving parts;
[0047] 35- elastic member;
[0048] 36-limiting piece;
[0049] 361- positioning slot;
[0050] 362-first gear;
[0051] 37-fixed sleeve;
[0052] 4-Display component;
[0053] 41- third gear;
[0054] 42-first display area;
[0055] 43- fourth gear;
[0056] 44-fifth gear;
[0057] 45-second display area;
[0058] 46-rotation axis;
[0059] 47-rotating member;
[0060] 5-Connect components;
[0061] 51- second gear;
[0062] 52-sixth gear;
[0063] 6-carrying platform;
[0064] 7- support member;
[0065] 71-adjustment device;
[0066] 72-first communication hole;
[0067] 73- second communication hole;
[0068] 74-Support column.
[0069] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and, together with the description, serve to explain the principles of the present application. DETAILED DESCRIPTION
[0070] In order to better understand the technical solution of the present application, the embodiments of the present application are described in detail below with reference to the accompanying drawings.
[0071] It should be clear that the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of this application.
[0072] The terms used in the embodiments of the present application are for the purpose of describing specific embodiments only and are not intended to limit the present application. The singular forms "a", "an", "the" and "the" used in the embodiments of the present application and the appended claims are also intended to include plural forms unless the context clearly indicates otherwise.
[0073] It should be understood that the term "and / or" as used herein is merely a description of the relationship between associated objects, indicating that three possible relationships exist. For example, "A and / or B" can represent: A exists alone, A and B exist simultaneously, or B exists alone. Furthermore, the character " / " in this document generally indicates that the associated objects are in an "or" relationship.
[0074] It should be noted that the directional words such as "upper", "lower", "left", and "right" described in the embodiments of the present application are described based on the angles shown in the accompanying drawings and should not be understood as limiting the embodiments of the present application. In addition, in the context, it should be understood that when it is mentioned that an element is connected to another element "on" or "under", it can not only be directly connected to the other element "on" or "under", but also be indirectly connected to the other element "on" or "under" through an intermediate element.
[0075] like Figure 1As shown, an embodiment of the present application provides a pipette, including a pipette component 1 and a control component 3. The control component 3 is connected to the pipette component 1 and can drive the pipette component 1 to inject a measurement droplet 21 into a detector 2. The pipette component 1 includes a first pipette gun 11 and a second pipette gun 12. The first pipette gun 11 is provided with a measurement droplet 21. The first pipette gun 11 and the second pipette gun 12 can simultaneously extend into a filling liquid 22 in the detector 2. When the first pipette gun 11 injects the measurement droplet 21 into the detector 2, the second pipette gun 12 can aspirate the same volume of filling liquid 22.
[0076] The detector 2 includes an upper substrate 25, a lower substrate 26, and a plastic frame 29. The upper and lower substrates 25, 26 are arranged sequentially along the thickness of the detector 2. The plastic frame 29 is located between the upper and lower substrates 25, 26 and is arranged along the edge of the detector. Together with the upper and lower substrates 25, 26, it forms a storage space. The storage space is filled with a filling liquid 22. When testing a measurement droplet 21, the measurement droplet 21 needs to be injected into the filling liquid 22. The small storage space in the detector 2 results in a high pressure inside the detector 2. When the first pipette 11 injects the measurement droplet 21 into the filling liquid 22, the second pipette 12 can aspirate the same volume of filling liquid 22 as the measurement droplet 21, reducing the pressure inside the detector 2, facilitating the injection of the measurement droplet 21 into the detector 2, and reducing the possibility of the measurement droplet 21 flowing back.
[0077] like Figure 1 and Figure 2 As shown, in a possible embodiment, along the direction of the control component 3 pointing to the pipetting component 1, the length of the second pipette gun 12 is greater than the length of the first pipette gun 11. After the pipetting component 1 is extended into the detector 2, the length of the second pipette gun 12 is greater than the length of the first pipette gun 11. When the pipette component is moved out of the detector 2, the first pipette gun 11 is moved out of the detector 2 earlier than the second pipette gun 12.
[0078] When the pipette is moved out of the detector 2, there is friction between the measurement droplet 21 and the first pipette 11. If the second pipette 12 is separated from the detector 2 first, when the first pipette 11 is separated from the detector 2, the friction between the measurement droplet 21 and the first pipette 11 may cause the measurement droplet 21 to flow back. If the first pipette 11 is separated from the detector 2 first, there is friction between the filling liquid 22 and the second pipette 12, which can reduce the possibility of the measurement droplet 21 flowing back.
[0079] The detector 2 may be a microfluidic chip. From the inside out, along the thickness direction of the microfluidic chip, it includes a filling liquid 22, a hydrophobic layer 23, an electrode 24, an upper substrate 25, and a lower substrate 26. The upper substrate 25 is provided with an injection hole 27 and an aspiration hole 28. The electrode 24 and the hydrophobic layer 23 near the upper substrate 25 are also provided with injection holes 27 and aspiration holes 28. A first pipette 11 extends through the injection hole 27 into the filling liquid 22 to inject a measurement droplet 21 into the filling liquid 22. A second pipette 12 extends through the aspiration hole 28 into the filling liquid 22 to aspirate an equal volume of filling liquid 22 to the measurement droplet 21, thereby reducing the pressure within the detector 2. The length difference between the first pipette 11 and the second pipette 12 may be half the distance between the upper and lower substrates 26. This allows the first pipette 11 to exit the detector 2 before the second pipette 12 when the pipette is removed from the detector 2, thereby reducing the possibility of backflow of the measurement droplet 21.
[0080] like Figure 2 As shown, in one possible embodiment, the first pipette 11 includes a first cavity 111, and the second pipette 12 includes a second cavity 121. A first piston 112 is provided in the first cavity 111 for injecting the measurement droplet 21 into the detector 2, and a second piston 122 is provided in the second cavity 121 for aspirating the filling liquid 22 out of the detector 2. The piston rod of the first piston 112 can protrude from the first cavity 111, and is provided with a connecting block 13 for connecting to the control component 3, which can control the movement of the first piston 112 along the height direction of the pipette. The end of the first cavity 111 away from the injection port is connected to the end of the second cavity 121 away from the aspiration port, forming a closed space between the first piston 112 and the second piston 122, so that the second piston 122 can move with the first piston 112.
[0081] A sealed space is formed between the first piston 112 and the second piston 122, ensuring that the volume of the measurement droplet 21 injected by the first pipette 11 after the movement of the second piston 122 is consistent with the volume of the filling liquid 22 aspirated by the second pipette 12. This reduces the pressure within the detector 2 during the injection of the measurement droplet 21, facilitating the injection of the measurement droplet 21 into the detector 2. Hydraulic oil can be injected into the sealed space between the first piston 112 and the second piston 122 to provide energy transfer, anti-wear, system lubrication, corrosion protection, and rust prevention. This ensures smoother movement of the first and second pistons 112, 122, and increases the service life of the pipetting assembly 1.
[0082] like Figure 3As shown, in a possible embodiment, the control component 3 includes a shell 31, and a driving member 32 and a push rod 33 are arranged in the shell 31. One end of the push rod 33 is connected to the driving member 32, and the other end is connected to the connecting block 13 in the pipetting component 1. The driving member 32 can extend out of the shell 31. Pressing the driving member 32 can drive the push rod 33 to move downward along the height direction of the pipette, and then can drive the connecting block 13 to move downward, so that the pipetting component 1 can inject the measurement droplet 21 into the detector 2.
[0083] One end of the push rod 33 connected to the connecting block 13 can be provided with a fixed sleeve 37. The fixed sleeve 37 is mounted on the connecting block 13, allowing the push rod 33 to push the push rod downward along the height direction of the pipette. A seal is provided between the fixed sleeve 37 and the connecting block 13. The seal can be made of rubber. The fixed sleeve 37 and the connecting block 13 are fixedly connected by the seal, and the push rod 33 can drive the push rod upward along the height direction of the pipette. The portion of the driving member 32 extending from the housing 31 is convenient for the user to press, thereby driving the pipetting assembly 1 to inject the measurement droplet 21 into the detector 2. The housing 31 can reduce the impact of the external environment on the driving member 32 and the push rod 33, which can increase the service life of the control assembly 3. At the same time, the housing 31 can limit the movement direction of the movable member 34, making the movement process of the driving member 32 and the push rod 33 more stable.
[0084] like Figure 3 As shown, in a possible embodiment, the control assembly 3 further includes a moving member 34, which is mounted on the top rod 33 so that the moving member 34 can move along with the top rod 33. In the projection along the height direction of the control assembly 3, the projected area of the moving member 34 is larger than the projected area of the top rod 33. An elastic member 35 is provided on the side of the moving member 34 away from the driving member 32. The elastic member 35 can be sleeved on the top rod 33 and connected to the moving member 34. The inner wall of the housing 31 is provided with a protrusion 311 protruding toward the direction close to the top rod 33. The top rod 33 can pass through the protrusion 311 and move along the height direction of the pipette. The end of the elastic member 35 away from the moving member 34 is connected to the protrusion 311.
[0085] When the push rod 33 moves downward along the height direction of the pipette, the movable member 34 compresses the elastic member 35. When the pressure applied to the driving member 32 is released, the movable member 34 and the push rod 33 will return to their initial positions under the elastic force of the elastic member 35, thereby driving the pipetting assembly 1 to return to its initial state.
[0086] like Figure 3As shown, in a possible embodiment, the control assembly 3 further includes a limiter 36, which is located between the driving member 32 and the movable member 34, with one end connected to the driving member 32 and the other end abutting against a side of the movable member 34 away from the elastic member 35. When the movable member 34 moves downward along the height direction of the pipette along with the push rod 33, the movable member 34 separates from the limiter 36, and when the elastic member 35 pushes the movable member 34 and the push rod 33 to reset, the movable member 34 abuts against the limiter 36. The limiter 36 is also connected to the inner wall of the housing 31 and can move relative to the housing 31 along the height direction of the pipette, and is used to control the position of the movable member 34 when the pipette is in the initial state.
[0087] If the limiter 36 moves upward along the height direction of the pipette, the distance between the limiter 36 and the protrusion 311 can be increased, and the movement amplitude of the movable member 34 can be increased, which is beneficial to increasing the volume of the measurement droplet 21 that can be transferred by the first pipette gun 11. If the limiter 36 moves downward along the height direction of the pipette, the distance between the limiter 36 and the protrusion 311 can be quietly reduced, and the movement amplitude of the movable member 34 can be reduced, which is beneficial to reducing the volume of the measurement droplet 21 that can be transferred by the first pipette gun 11. Therefore, the position of the limiter 36 in the control component 3 can control the volume of the measurement droplet 21 that can be transferred by the pipette.
[0088] In a possible embodiment, a step is provided at the connection between the moving member 34 and the limiting member 36, which improves the accuracy of the abutment between the moving member 34 and the limiting member 36, and helps to reduce the possibility of shaking of the push rod 33 and the moving member 34 during movement.
[0089] like Figure 3 and Figure 4 As shown, in one possible embodiment, the limiting member 36 is threadedly connected to the housing 31. When the limiting member 36 moves along the height direction of the pipette, it needs to rotate relative to the housing 31. One of the driving member 32 and the limiting member 36 includes a positioning groove 361, and the other includes a positioning protrusion 321. The positioning groove 361 and the positioning protrusion 321 are recessed or protruded in the radial direction of the control assembly 3, and are used to limit the relative position between the driving member 32 and the limiting member 36 along the circumferential direction of the control assembly 3.
[0090] Taking the positioning groove 361 located on the limiting member 36 and the positioning protrusion 321 located on the driving member 32 as an example, one end of the limiting member 36 can extend into the driving member 32, and the inner wall of the driving member 32 where the limiting member 36 contacts the limiting member 36 is provided with a positioning protrusion 321. The side wall of the limiting member 36 adjacent to the driving member 32 is provided with a positioning groove 361, and the positioning protrusion 321 can extend into the positioning groove 361, thereby limiting the relative position of the limiting member 36 and the driving member 32 along the circumferential direction of the control assembly 3. When the driving member 32 is rotated, the limiting member 36 can be driven to rotate. A gap is provided between the limiting member 36 and the driving member 32, which can reduce the impact on the limiting member 36 when the driving member 32 is pressed, so that the limiting member 36 maintains its current position. A gap is provided between the push rod 33 and the limiting member 36, which can reduce the impact of the push rod 33 when the driving member 32 drives the limiting member 36 to rotate, reducing the possibility of the push rod 33 rotating accordingly.
[0091] like Figure 4 As shown, in a possible embodiment, a recessed portion 322 is provided on the outer surface of the driving member 32 to facilitate the user to rotate the driving member 32. Recesses or protrusions of different shapes can also be provided on the outer surface of the driving member 32 to facilitate the rotation of the driving member 32.
[0092] like Figure 5 As shown, in a possible embodiment, the pipette also includes a display component 4 and a connecting component 5. The display component 4 is used to display the position of the limiter 36, so that the amount of the measuring droplet 21 that the pipette can transfer can be known. The connecting component 5 is located between the display component 4 and the limiter component and is used to transmit the position information of the limiter component to the display component 4.
[0093] The display assembly 4 can display the amount of the measuring droplet 21 that the pipette can transfer, thereby improving the accuracy of the volume of the measuring droplet 21 transferred by the pipette. When adjusting the position of the stopper 36, the display assembly 4 can be used to indicate the amount of the measuring droplet 21 that the pipette can transfer, thereby improving the accuracy of the adjustment of the stopper 36.
[0094] like Figure 5 and Figure 6 As shown, in a possible embodiment, the limiting member 36 includes a first gear 362, which can rotate with the limiting member 36. The connecting assembly 5 includes a second gear 51, which is engaged with the first gear 362 and can rotate with the first gear 362. The display assembly 4 includes a third gear 41, which is engaged with the second gear 51 and can rotate with the second gear 51. The display assembly 4 also includes a rotating shaft 46, which is coaxially arranged with the third gear 41 and has a first display area 42 arranged on the rotating shaft 46. When the third gear 41 rotates, the rotating shaft 46 also rotates, thereby changing the reading in the first display area 42 according to the rotation of the third gear 41.
[0095] To adjust the position of the limiter 36 in the control assembly 3, the limiter 36 needs to be rotated. Consequently, the limiter 36 drives the first gear 362 to rotate. Through the second gear 51, the first gear 362 drives the third gear 41 to rotate, and the rotation shaft 46 rotates along with the third gear 41. The display assembly 4 is located within the housing 31, and a display window is provided in the display area of the rotation shaft 46. As the rotation shaft 46 rotates, the corresponding number in the display window changes, thereby indicating the volume of the measurement droplet 21 that the pipette can transfer.
[0096] like Figure 1 As shown, in a possible embodiment, the end of the push rod 33 away from the driving member 32 is connected to the first piston 112 through a connecting member and a push rod. The movement of the push rod 33 can drive the first piston 112 to move. The limiter 36 can limit the movement amplitude of the push rod 33, and then limit the movement amplitude of the first piston 112, thereby controlling the volume of droplets that the pipette can transfer. The number of teeth of the first gear 362 is X, the unit distance of movement of the limiter 36 is W, and the limiter 36 moves a unit distance in the height direction of the pipette, which requires the limiter 36 to rotate one circle along its circumference. The number of teeth of the second gear 51 is Y, and the diameter of the first pipette gun 11 is φ. The relationship between X, Y, W and φ is: X / Y = [π·(φ / 2) 2 ]·W.
[0097] As can be seen from the above formula, the gear ratio of the first gear 362 and the second gear 51 is consistent with the value of the volume of the measurement droplet 21 that the pipette can transfer after the limiter 36 rotates one circle. By changing the number of teeth of the first gear 362 or the second gear 51, the value displayed in the first display area 42 can be made to show the volume of the measurement droplet 21 that the pipette can transfer after the limiter 36 rotates one circle.
[0098] like Figure 5 、 Figure 7 and Figure 8As shown, in one possible embodiment, the display assembly 4 includes a fourth gear 43, which is mounted on a rotating shaft 46 and can rotate with the rotating shaft 46. The connecting assembly 5 includes a sixth gear 52, which meshes with the fourth gear 43. The display assembly 4 includes a rotating member 47, which is mounted on one end of the rotating shaft 46 and can rotate relative to the rotating shaft 46. The rotating member 47 is provided with a fifth gear 44 and a second display area 45. The fifth gear 44 meshes with the sixth gear 52 to drive the second display area 45 to rotate. A display window is also provided at a position corresponding to the second display area 45 on the housing 31. Rotation of the second display area causes the display window to display a different value. The fourth gear 43 has a number of teeth n1, and the second gear 51, the third gear 41, the fifth gear 44, and the sixth gear 52 all have a number of teeth n2, where n1 < n2.
[0099] For example, if the first display area 42 and the second display area 45 are in decimal, with the value displayed in the first display area 42 being the ones digit and the value displayed in the second display area 45 being the tens digit, and n1:n2 = 1:10, then driven by the first gear 362, the second gear 51 and the third gear 41 rotate ten teeth, causing the value in the first display area 42 to increase by ten. Driven by the rotating shaft 46, the fourth gear 43, coaxially arranged with the third gear 41, rotates one tooth, thereby driving the sixth gear 52 and the fifth gear 44 to rotate one tooth, causing the value in the second display area 45 to increase by one, thus satisfying decimal counting. The ratio of n1 and n2 can also be changed according to specific usage, thereby changing the base of the first display area 42 and the second display area 45.
[0100] like Figure 3 As shown, in one possible embodiment, the display assembly 4 is located within the housing 31. The housing 31 reduces the impact of the external environment on the fit accuracy between the various gears in the display assembly 4, thereby improving the accuracy of the display assembly 4. Display windows are provided at positions corresponding to the first display area 42 and the second display area 45 of the housing 31, making it easier for the operator to read the readings in the first display area 42 and the second display area 45 through the display windows.
[0101] like Figure 9 As shown, the embodiment of the present application further provides an operating table, through which the above-mentioned pipette injects the measurement droplet 21 into the detector 2. The operating table includes a carrying platform 6 and a support member 7, the support member 7 is connected to the carrying platform 6, and a first connecting hole 72 and a second connecting hole 73 are provided on a plane parallel to the carrying platform 6. The detector 2 is fixed to the carrying platform 6, the injection hole 27 corresponds to the first connecting hole 72, and the first pipette gun 11 can pass through the first connecting hole 72 to extend into the injection hole 27, the aspiration hole 28 corresponds to the second connecting hole 73, and the second pipette gun 12 can pass through the second connecting hole 73 to extend into the aspiration hole 28.
[0102] The carrying platform 6 can limit the position of the detector 2 , and the support member 7 can limit the position of the pipette, which is beneficial to improving the accuracy of the pipette when it is inserted into the detector 2 and facilitates the operator to inject the measurement droplet 21 into the detector 2 .
[0103] like Figure 9 As shown, in a possible embodiment, the support column 74 connecting the support member 7 and the carrying platform 6 can pass through the carrying platform 6, and an adjustment device 71 is provided on one end passing through the carrying platform 6 for adjusting the relative position between the carrying platform 6 and the support member 7.
[0104] The adjusting device 71 and the support column 74 can be connected by a threaded connection. By rotating the adjusting device 71, the position of the adjusting device on the support column 74 can be adjusted, thereby changing the distance between the supporting platform 6 and the plane where the first connecting hole 72 and the second connecting hole 73 are provided, so that the operating table can be suitable for pipettes equipped with first pipette guns 11 and second pipette guns 12 of different lengths.
[0105] An embodiment of the present application provides a pipette and an operating table. The pipette includes a pipette assembly 1 and a control assembly 3. The control assembly 3 is connected to the pipette assembly 1 and is used to drive the pipette assembly 1 to inject a measurement droplet 21 into a detector 2. The pipette assembly 1 includes a first pipette gun 11 and a second pipette gun 12. Both the first pipette gun 11 and the second pipette gun 12 can be extended into the detector 2. The first pipette gun 11 is used to inject the measurement droplet 21 into the detector 2, and the second pipette gun 12 is used to aspirate a filling liquid 22 within the detector 2, with the volume of the aspirated filling liquid 22 being consistent with the volume of the measurement droplet 21. Aspirating the filling liquid 22 by the second pipette gun 12 can reduce the pressure in the detector 2, thereby facilitating the first pipette gun 11 to inject the measurement droplet 21 into the detector 2.
[0106] The above description is merely a preferred embodiment of the present application and is not intended to limit the present application. Various modifications and variations are possible for those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.
Claims
1. A pipette, characterized in that The pipette comprises: A pipetting assembly (1) for injecting a measuring liquid droplet (21) into a detector (2); a control component (3), the control component (3) being connected to the pipetting component (1) and being used to drive the pipetting component (1) to move; The pipetting assembly (1) comprises a first pipette (11) and a second pipette (12), both of which are capable of extending into the detector (2), the first pipette (11) being used to inject a measuring droplet (21) into the detector (2), and the second pipette (12) being used to suck out a filling liquid (22) in the detector (2), and the volume of the measuring droplet (21) injected by the first pipette (11) being consistent with the volume of the filling liquid (22) sucked out by the second pipette (12); The first pipette gun (11) includes a first cavity (111) and a first piston (112), and one end of the first piston (112) protruding from the first cavity (111) is provided with a connecting block (13) for connecting with the control component (3), and the connecting block (13) can drive the first piston (112) to move relative to the first cavity (111). The second pipette gun (12) includes a second cavity (121) and a second piston (122), and the second cavity (121) is connected to the first cavity (111). There is a sealed space between the side of the first piston (112) extending into the detector (2) away from the first pipette gun (11) and the side of the second piston (122) extending into the detector (2) away from the second pipette gun (12). When the first piston (112) moves along the end close to the first pipette gun (11) extending into the detector (2), the second piston (122) moves along the end away from the second pipette gun (12) extending into the detector (2).
2. The pipette according to claim 1, characterized in that Along the direction from the control component (3) to the pipetting component (1), the length of the second pipetting gun (12) is greater than the length of the first pipetting gun (11).
3. The pipette according to claim 1, characterized in that The control assembly (3) comprises a housing (31), a driving member (32) and a push rod (33), wherein at least a portion of the driving member (32) is capable of protruding from the housing (31), one end of the push rod (33) is connected to the driving member (32), and the other end is connected to the pipetting assembly (1), and is capable of moving along the height direction of the pipette with the driving member (32).
4. The pipette according to claim 3, characterized in that The control assembly (3) further comprises a moving member (34) and an elastic member (35). The moving member (34) is mounted on the push rod (33) and is capable of moving with the push rod (33). The elastic member (35) is located on a side of the moving member (34) away from the driving member (32), and one end away from the moving member (34) is connected to the housing (31).
5. The pipette according to claim 4, characterized in that The control assembly (3) further comprises a limiting member (36), the limiting member (36) being connected to the inner wall of the housing (31) and being capable of moving along the height direction of the pipette, the side of the moving member (34) away from the elastic member (35) being capable of abutting against the side of the limiting member (36) away from the driving member (32), and the limiting member (36) being capable of limiting the movement distance of the moving member (34).
6. The pipette according to claim 5, characterized in that One of the limiting member (36) and the driving member (32) includes a positioning groove (361), and the other includes a positioning protrusion (321), wherein the positioning protrusion (321) can extend into the positioning groove (361) and is used to limit the relative position between the driving member (32) and the limiting member (36) along the circumference of the limiting member (36); The limiting member (36) is threadedly connected to the housing (31). When the driving member (32) rotates, the limiting member (36) can rotate along with the driving member and move along the height direction of the pipette.
7. The pipette according to claim 5, characterized in that The pipette further comprises a display component (4) and a connection component (5), wherein the display component (4) is connected to the limiting member (36) via the connection component (5) and is used for displaying the position of the limiting member (36).
8. The pipette according to claim 7, characterized in that The limiting member (36) includes a first gear (362), the connecting assembly (5) includes a second gear (51), and the display assembly (4) includes a third gear (41). The third gear (41) is engaged with the first gear (362) through the second gear (51), and the first gear (362) can drive the third gear (41) to rotate. The display assembly (4) further comprises a first display area (42), which is coaxially arranged with the third gear (41) and can rotate with the third gear (41) to display the position of the limiting member (36).
9. The pipette according to claim 8, characterized in that The display component (4) includes a fourth gear (43), a fifth gear (44) and a second display area (45); the connecting component (5) includes a sixth gear (52); the fourth gear (43) is coaxially arranged with the third gear (41) and can rotate with the third gear (41); the fourth gear (43) and the fifth gear (44) are both engaged with the sixth gear (52); the fourth gear (43) drives the fifth gear (44) to rotate through the sixth gear (52); the number of teeth of the fourth gear (43) is n1, and the number of teeth of the second gear (51), the third gear (41), the fifth gear (44) and the sixth gear (52) are all n2, wherein n1<n2; The second display area (45) is connected to the fifth gear (44) and can rotate along with the fifth gear (44).
10. The pipette according to claim 8, characterized in that The push rod (33) is connected to the first pipette (11) and is used to drive the first piston (112) of the first pipette (11) to move so as to push out the measuring droplet (21). The number of teeth of the first gear (362) is X, the number of teeth of the second gear (51) is Y, the unit distance of movement of the limiter (36) along the height direction of the pipette is W, and the diameter of the first pipette (11) is φ, wherein the relationship between X, Y, W and φ is: X / Y=[π·(φ / 2) 2 ]·W.
11. An operating table, characterized in that: The operating table includes a carrying platform (6) and a support member (7), wherein the support member (7) is connected to the carrying platform (6), and the carrying platform (6) is used to carry the detector (2). The pipette can pass through the support member (7) and extend into the detector (2), and the pipette is the pipette according to any one of claims 1 to 10.
12. The operating table according to claim 11, characterized in that: The support member (7) comprises an adjusting device (71), which is located on a side of the carrying platform (6) away from the detector (2) and is used to adjust the relative position of the carrying platform (6) and the support member (7).
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