A highly efficient anti-parasitic ivermectin preparation device and preparation process
By designing an ivermectin preparation device containing a preparation mechanism and a crystallization mechanism, the inconvenience of transporting and crystallization treatment of the crude ivermectin solution in the prior art is solved, and efficient stirring and crystallization processing of the ivermectin solution is achieved, and the purity and yield of the product are improved.
Patent Information
- Application Number
- CN202310436310.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-04-23
- Publication Date
- 2025-05-16
- Estimated Expiration
- 2043-04-23
AI Technical Summary
The existing high-efficiency anti-parasitic ivermectin preparation device and preparation process cannot deliver the ivermectin crude product solution in real time, and lacks a structure to replace a large number of seeds, which makes it inconvenient to add and process the ivermectin crude product and crystallization treatment.
An efficient anti-parasitic special ivermectin preparation device is designed including a preparation mechanism and a crystallization mechanism. The preparation mechanism includes a storage assembly, a feed assembly and a stirring assembly for temporary storage, quantitative delivery and stirring of the crude ivermectin solution. The crystallization mechanism includes a limiting assembly, a replacement assembly, a reaction assembly and a heating assembly for ease of seed replacement and crystallization processing.
Through this device, real-time quantitative addition and stirring of the crude ivermectin solution can be achieved, the processing efficiency of the crude ivermectin product is improved, and the crystallization processing of the crude ivermectin product is facilitated, thereby improving the purity and yield of the product.
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Figure CN116492958B_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of ivermectin preparation, and particularly relates to a high-efficiency anti-parasitic special ivermectin preparation device and a preparation process. Background Art
[0002] Ivermectin, a highly effective antiparasitic drug, is a new type of broad-spectrum, highly effective, low-toxic antibiotic antiparasitic drug. It has a good killing effect on parasites inside and outside the body, especially nematodes and arthropods, and is often used for the treatment of animals. When preparing ivermectin, toluene and avermectin are added to the reactor in a reaction kettle, and a catalyst is added under the protection of protective gas. After the protective gas is replaced with hydrogen, the heating temperature is adjusted to 65-75°C and the pressure is 0.5-0.7MPa. Avermectin reacts with hydrogen to obtain ivermectin crude product. The ivermectin crude product is dissolved in a solvent, heated and stirred until completely dissolved and kept warm to obtain a crude solution. Purified water and formamide are added to the crude solution and the flow rate is controlled. The solution is cooled to obtain a diluent. Crystal seeds are added to the diluent and crystals are grown. The diluent is cooled to a certain temperature by a temperature control method. Finally, high-purity ivermectin powder is obtained by filtration, washing and drying.
[0003] The existing high-efficiency anti-parasitic ivermectin preparation device and preparation process have the following disadvantages during preparation:
[0004] 1. It is impossible to quantitatively deliver the crude ivermectin solution in real time according to the required requirements, which is inconvenient for adding and processing the crude ivermectin;
[0005] 2. The lack of a structure for replacing a large number of crystal seeds makes it inconvenient to process the crystallization of the crude ivermectin solution. Summary of the invention
[0006] The purpose of the present invention is to solve the following problems for an existing high-efficiency anti-parasitic ivermectin preparation device and preparation process:
[0007] 1. It is impossible to quantitatively deliver the crude ivermectin solution in real time according to the required requirements, which is inconvenient for adding and processing the crude ivermectin;
[0008] 2. The lack of a structure for replacing a large number of crystal seeds makes it inconvenient to process the crystallization of the crude ivermectin solution.
[0009] The above technical purpose of the present invention is achieved through the following technical solutions: a high-efficiency anti-parasitic ivermectin preparation device and preparation process, including a preparation mechanism and a crystallization mechanism, the preparation mechanism includes a storage component, a feeding component and a stirring component, the feeding component is connected to the rear side of the top of the storage component, the stirring component is bolted to the top of the storage component, the crystallization mechanism includes a limit component, a replacement component, a reaction component and a heating component, the limit component is bolted to the bottom of the storage component, the replacement component is clamped on the inner wall of the limit component, the reaction component is clamped on the inner wall of the replacement component, and the heating component is bolted to the inner wall of the reaction component.
[0010] By adopting the above technical scheme, a preparation mechanism and a crystallization mechanism are set up. The preparation mechanism can perform fine stirring processing on the ivermectin crude solution after being connected to the external ivermectin crude solution conveying equipment, and discharge the waste gas generated by the ivermectin after the preparation is completed. The crystallization mechanism can facilitate the replacement of crystal seeds and perform crystallization processing on the ivermectin crude solution.
[0011] The present invention is further configured as follows: the storage assembly includes a storage tank, a support ring and an exhaust fan, the support ring is bolted to the top of the storage tank, and the exhaust fan is bolted to the front side of the top of the storage tank.
[0012] By adopting the above technical scheme, by setting up a storage component, the storage tank can temporarily store the ivermectin crude solution, which is convenient for the stirring component to stir the ivermectin crude solution. The support ring can support and limit the feeding component. The exhaust fan can discharge the waste gas generated by the ivermectin crude solution in the storage tank after power is turned on and started.
[0013] The present invention is further configured as follows: the feeding assembly includes a feed pump, a storage pipe and a valve, the valve is connected to the rear side of the top of the storage tank, the storage pipe is connected to the top of the valve, and the feed pump is connected to the top of the storage pipe.
[0014] By adopting the above technical scheme, by setting up a feeding component, the feed pump can be externally connected to the ivermectin crude solution conveying equipment, and after being powered on and started, the ivermectin crude solution can be pumped into the discharge pipe. The storage pipe is a storage pipe with a glass observation window structure, which can quantitatively store the ivermectin crude solution to facilitate real-time addition of the ivermectin crude solution. The valve can open and close the storage pipe, which can facilitate the storage pipe to convey the ivermectin crude solution to the storage tank.
[0015] The present invention is further configured as follows: the stirring assembly includes a servo motor, a rotating rod and a stirring tube, the servo motor is bolted to the top of the storage tank, the rotating rod is bolted to the output end of the bottom of the servo motor, the rotating rod passes through the top of the storage tank and is rotatably connected to the top of the storage tank, and the stirring tube is connected to the surface of the rotating rod.
[0016] By adopting the above technical solution and setting a stirring assembly, the servo motor can convert electrical energy into rotational mechanical energy after being powered on and started, and then transmit the rotational mechanical energy to the rotating rod, which can drive the stirring tube to rotate with the servo motor. The stirring tube has two 90-degree elbows at both ends, and the inlets of the elbows are water pipes arranged in the same direction. When the stirring tube rotates, the inlet of the elbow at one end of the stirring tube will contact and move with the solution, and the solution will be transported into the stirring tube, and then transmitted to the elbow at the other end. The inlet of the elbow at the other end will move away from the solution, so as not to affect the solution from being delivered from the inlet of the elbow at the other end. The solution passing through the inside of the stirring tube will be squeezed by the stirring tube to increase the efficiency of solution mixing.
[0017] The present invention is further configured as follows: the limit assembly includes a limit box, a limit slide and an access slot, the limit box is bolted to the bottom of the storage tank, the limit slide is bolted to the front side of the inner wall of the limit box and the rear side of the inner wall, and the access slot is opened on the right side of the limit box.
[0018] By adopting the above technical solution, a limit assembly is set up, the limit box can support and limit the replacement assembly, the limit slide can increase the stability of the replacement assembly when sliding, and the access slot can temporarily store the replacement assembly to facilitate the replacement of the crystal seed by the replacement assembly.
[0019] The present invention is further configured as follows: the replacement component includes a limit frame, a limit slot and a closing plate, the limit frame is arranged on the inner side of the limit box, the front and rear sides of the limit frame are slidably connected to the surface of the limit slide plate, the limit slot is opened on the inner wall of the limit frame, the closing plate is bolted to the right side of the limit frame, and the surface of the limit frame is in contact with the access slot.
[0020] By adopting the above technical solution, by setting up a replacement component, the limit frame can drive the reaction component to move, the limit slot can support and limit the reaction component, which is convenient for replacing the reaction component, and the closing plate can contact the access slot to increase the sealing inside the limit box.
[0021] The present invention is further configured as follows: the reaction component includes a limiting ring plate, a storage box and an installation groove, the storage box is clamped on the inner wall of the limiting slot, the installation groove is opened at the bottom of the inner wall of the storage box, the limiting ring plate is bolted to the top of the storage box surface, and the surface of the limiting ring plate is in contact with the inner wall of the limiting slot.
[0022] By adopting the above technical solution, through setting the reaction component, the limiting ring plate can increase the stability of the storage box when it is placed in the limiting card slot, the storage box can temporarily store the crystal seeds, so as to facilitate the crystallization processing of the ivermectin crude solution, and the mounting groove can support and limit the heating component, so as to facilitate the heating component to perform auxiliary heating on the crystal seeds and improve the efficiency of the crystallization processing.
[0023] The present invention is further configured as follows: the heating assembly includes a heat conducting plate, a heat conducting ring and a heater, the heat conducting plate is clamped on the inner wall of the mounting groove, the heat conducting ring is welded on both sides of the inner wall of the heat conducting plate, the heater is bolted to the bottom of the heat conducting plate, and the bottom of the heater passes through the bottom of the storage box and is bolted to the storage box.
[0024] By adopting the above technical solution, by setting up a heating component, the heater can convert electrical energy into thermal energy after being powered on and started, and then transfer the thermal energy to the heat conductive plate, the heat conductive plate can transfer the thermal energy to the heat conductive ring, and the heat conductive plate and the heat conductive ring can transfer heat to the ivermectin crude solution, thereby increasing the efficiency of the ivermectin crude solution and the seed crystallization processing.
[0025] The present invention is further configured as follows: there are five stirring tubes in total, and the stirring tubes are made of stainless steel.
[0026] By adopting the above technical solution, five stirring tubes are provided, which can greatly improve the efficiency of stirring the ivermectin crude solution, and the stirring tubes made of stainless steel have high hardness and toughness, as well as high corrosion resistance, thereby improving the service life of the stirring tubes.
[0027] A preparation process of a highly effective antiparasitic ivermectin comprises the following steps:
[0028] S1. Feeding and stirring: First, the feed pump is externally connected to the output end of the ivermectin crude solution conveying equipment, and then the preparation mechanism is powered on and started. When the ivermectin crude solution enters the storage tank, the servo motor converts electrical energy into rotational mechanical energy, and then transmits the rotational mechanical energy to the rotating rod. The rotating rod rotates with the servo motor and drives the stirring tube to rotate. The ivermectin crude solution moves with the stirring of the stirring tube and forms a vortex. At the same time, the ivermectin crude solution passes through the stirring tube when moving. After the stirring process of the ivermectin crude solution is completed, the crystallization mechanism is allowed to crystallize the ivermectin crude solution. After the crystallization process of the ivermectin crude solution is completed, the exhaust fan discharges the excess gas after the reaction in the storage tank until the preparation of ivermectin is completed;
[0029] S2. Heating and crystallizing: First, put the seed crystal into the storage box, then put the storage box into the limit card slot, and put the limit frame into the limit box along the limit slide until the closing plate contacts and closes the access slot, and then the ivermectin crude solution that has completed the stirring process is transported to the storage box, and then the crystallization mechanism is powered on and started. The heater will convert electrical energy into thermal energy after power-on, and then transfer the thermal energy to the heat conduction plate, which will transfer the heat to the heat conduction ring. The heat conduction plate and the heat conduction ring will transfer the heat to the ivermectin crude solution, and the ivermectin crude solution will gradually produce a crystallization reaction with the seed crystal due to the heat, until the ivermectin crude solution and the seed crystal completely complete the crystallization reaction, then the limit frame can be taken out from the access slot, and the prepared ivermectin can be taken out.
[0030] In summary, the present invention has the following beneficial effects:
[0031] 1. By setting up a preparation mechanism, the storage component can temporarily store the ivermectin crude solution, the feeding component can transport the ivermectin crude solution to the storage component after being externally connected to the ivermectin crude solution conveying equipment, and the stirring component can stir and mix the ivermectin crude solution, so as to facilitate the subsequent crystallization processing of the ivermectin crude solution;
[0032] 2. By setting a crystallization mechanism, the limiting component can support and limit the replacement component, and can temporarily store the ivermectin crude solution. The replacement component can drive the reaction component to move, which is convenient for taking out and storing the reaction component from the limiting component. The reaction component can replace the crystal seeds and temporarily store the crystal seeds, which is convenient for the crystal seeds and the ivermectin crude solution to be crystallized. The heating component can heat the crystal seeds and the ivermectin crude solution in the reaction component, thereby increasing the efficiency of the crystallization processing of ivermectin and the crystal seeds. BRIEF DESCRIPTION OF THE DRAWINGS
[0033] Figure 1 It is a schematic diagram of the overall structure of the present invention;
[0034] Figure 2 It is a schematic diagram of the structure of the preparation mechanism of the present invention;
[0035] Figure 3 It is a schematic diagram of the storage assembly structure of the present invention;
[0036] Figure 4 It is a schematic diagram of the structure of the feeding group of the present invention;
[0037] Figure 5 It is a schematic diagram of the structure of the stirring assembly of the present invention;
[0038] Figure 6 It is a schematic diagram of the crystallization mechanism structure of the present invention;
[0039] Figure 7 It is a schematic diagram of the structure of the limit assembly of the present invention;
[0040] Figure 8 It is a schematic diagram of the structure of the replacement assembly of the present invention;
[0041] Fig. 9 It is a schematic diagram of the reaction assembly structure of the present invention;
[0042] Fig.10 It is a schematic diagram of the heating component structure of the present invention.
[0043] 1. Preparation mechanism; 101. Storage component; 1011. Storage tank; 1012. Support ring; 1013. Exhaust fan; 102. Feeding component; 1021. Feeding pump; 1022. Storage tube; 1023. Valve; 103. Stirring component; 1031. Servo motor; 1032. Rotating rod; 1033. Stirring tube; 2. Crystallization mechanism; 201. Limiting component; 2011. Limiting box; 2012. Limiting slide plate; 2013. Access slot; 202. Replacement component; 2021. Limiting frame; 2022. Limiting card slot; 2023. Closing plate; 203. Reaction component; 2031. Limiting ring plate; 2032. Storage box; 2033. Mounting slot; 204. Heating component; 2041. Heat conducting plate; 2042. Heat conducting ring; 2043. Heater. DETAILED DESCRIPTION
[0044] The present invention is further described in detail below in conjunction with the accompanying drawings.
[0045] Embodiment 1:
[0046] refer to Figure 1-5 A highly efficient antiparasitic ivermectin preparation device comprises a preparation mechanism 1, wherein the preparation mechanism 1 comprises a storage component 101, a feeding component 102 and a stirring component 103, wherein the feeding component 102 is connected to the rear side of the top of the storage component 101, and the stirring component 103 is bolted to the top of the storage component 101. By setting the preparation mechanism 1, the storage component 101 can temporarily store the ivermectin crude solution, and after the feeding component 102 is externally connected to the ivermectin crude solution conveying equipment, the ivermectin crude solution is conveyed into the storage component 101, and the stirring component 103 can stir and mix the ivermectin crude solution, so as to facilitate the subsequent crystallization processing of the ivermectin crude solution.
[0047] like Figure 3As shown, the storage component 101 includes a storage tank 1011, a support ring 1012 and an exhaust fan 1013. The support ring 1012 is bolted to the top of the storage tank 1011, and the exhaust fan 1013 is bolted to the front side of the top of the storage tank 1011. By setting the storage component 101, the storage tank 1011 can temporarily store the ivermectin crude solution, which is convenient for the stirring component 103 to stir the ivermectin crude solution. The support ring 1012 can support and limit the feeding component 102. The exhaust fan 1013 can discharge the waste gas generated by the ivermectin crude solution in the storage tank 1011 after power is turned on and started.
[0048] like Figure 4 As shown, the feeding assembly 102 includes a feed pump 1021, a storage pipe 1022 and a valve 1023. The valve 1023 is connected to the rear side of the top of the storage tank 1011, the storage pipe 1022 is connected to the top of the valve 1023, and the feed pump 1021 is connected to the top of the storage pipe 1022. By setting the feeding assembly 102, the feed pump 1021 can be externally connected to the ivermectin crude solution conveying equipment, and after power-on and start-up, the ivermectin crude solution can be pumped into the discharge pipe. The storage pipe 1022 is a storage pipe with a glass observation window structure, which can quantitatively store the ivermectin crude solution to facilitate real-time addition of the ivermectin crude solution. The valve 1023 can open and close the storage pipe 1022, which can facilitate the storage pipe 1022 to convey the ivermectin crude solution to the storage tank 1011.
[0049] like Figure 5 As shown, the stirring assembly 103 includes a servo motor 1031, a rotating rod 1032 and a stirring tube 1033. The servo motor 1031 is bolted to the top of the storage tank 1011, and the rotating rod 1032 is bolted to the output end at the bottom of the servo motor 1031. The rotating rod 1032 penetrates the top of the storage tank 1011 and is rotatably connected to the top of the storage tank 1011. The stirring tube 1033 is connected to the surface of the rotating rod 1032. By setting the stirring assembly 103, the servo motor 1031 can convert electrical energy into rotational mechanical energy after being powered on and started, and then transmit the rotational mechanical energy to the rotating rod 1032. The stirring tube 1033 can be driven to rotate along with the servo motor 1031. The stirring tube 1033 has two 90-degree elbows at both ends, and the inlets of the elbows are water pipes arranged in the same direction. When the stirring tube 1033 rotates, the inlet of the elbow at one end of the stirring tube 1033 will contact and move with the solution, and the solution will be transported into the stirring tube 1033 and then transmitted to the elbow at the other end. The inlet of the elbow at the other end will move away from the solution, thereby not affecting the solution from being delivered from the inlet of the elbow at the other end. The solution passing through the stirring tube 1033 will be squeezed by the stirring tube 1033 to increase the efficiency of solution mixing.
[0050] like Figure 5 As shown, there are five stirring tubes 1033, which are made of stainless steel. By providing five stirring tubes 1033, the five stirring tubes 1033 can greatly improve the efficiency of stirring the ivermectin crude solution, and the stirring tubes 1033 made of stainless steel have higher hardness and toughness, as well as higher corrosion resistance, thereby improving the service life of the stirring tubes 1033.
[0051] Brief description of the use process: First, the feed pump 1021 is externally connected to the output end of the ivermectin crude solution conveying equipment, and then the preparation mechanism 1 is powered on and started. When the ivermectin crude solution enters the storage tank 1011, the servo motor 1031 will convert electrical energy into rotational mechanical energy, and then transfer the rotational mechanical energy to the rotating rod 1032. The rotating rod 1032 will rotate with the servo motor 1031, and drive the stirring tube 1033 to rotate. The ivermectin crude solution will move with the stirring of the stirring tube 1033 and form a vortex. At the same time, the ivermectin crude solution will pass through the stirring tube 1033 when moving. After the stirring process of the ivermectin crude solution is completed, the crystallization mechanism 2 is allowed to crystallize the ivermectin crude solution. After the crystallization process of the ivermectin crude solution is completed, the exhaust fan 1013 discharges the excess gas after the reaction in the storage tank 1011 until the preparation of ivermectin is completed.
[0052] Embodiment 2:
[0053] refer to Figure 6-10 A highly efficient antiparasitic ivermectin preparation device comprises a crystallization mechanism 2, wherein the crystallization mechanism 2 comprises a limiting component 201, a replacement component 202, a reaction component 203 and a heating component 204, wherein the limiting component 201 is bolted to the bottom of the storage component 101, the replacement component 202 is clamped to the inner wall of the limiting component 201, the reaction component 203 is clamped to the inner wall of the replacement component 202, and the heating component 204 is bolted to the inner wall of the reaction component 203. By setting the crystallization mechanism 2, the limiting component 201 can support the replacement component 202 The replacement component 202 can drive the reaction component 203 to move, so that the reaction component 203 can be taken out and stored in the limiting component 201. The reaction component 203 can replace the crystal seeds and temporarily store the crystal seeds, so that the crystal seeds and the ivermectin crude solution can be crystallized. The heating component 204 can heat the crystal seeds and the ivermectin crude solution in the reaction component 203, thereby increasing the efficiency of the crystallization processing of ivermectin and the crystal seeds.
[0054] like Figure 7As shown, the limit assembly 201 includes a limit box 2011, a limit slide 2012 and an access slot 2013. The limit box 2011 is bolted to the bottom of the storage tank 1011, the limit slide 2012 is bolted to the front side of the inner wall of the limit box 2011 and the rear side of the inner wall, and the access slot 2013 is opened on the right side of the limit box 2011. By setting the limit assembly 201, the limit box 2011 can support and limit the replacement assembly 202, the limit slide 2012 can increase the stability of the replacement assembly 202 when sliding, and the access slot 2013 can temporarily store the replacement assembly 202 to facilitate the replacement of the crystal seed by the replacement assembly 202.
[0055] like Figure 8 As shown, the replacement component 202 includes a limit frame 2021, a limit slot 2022 and a closing plate 2023. The limit frame 2021 is arranged on the inner side of the limit box 2011. The front and rear sides of the limit frame 2021 are slidably connected to the surface of the limit slide 2012. The limit slot 2022 is opened on the inner wall of the limit frame 2021. The closing plate 2023 is bolted to the right side of the limit frame 2021. The surface of the limit frame 2021 is in contact with the access slot 2013. By setting the replacement component 202, the limit frame 2021 can drive the reaction component 203 to move, the limit slot 2022 can support and limit the reaction component 203, so as to facilitate the replacement of the reaction component 203. The closing plate 2023 can be in contact with the access slot 2013 to increase the sealing inside the limit box 2011.
[0056] like Fig. 9 As shown, the reaction component 203 includes a limiting ring plate 2031, a storage box 2032 and a mounting groove 2033. The storage box 2032 is clamped on the inner wall of the limiting groove 2022. The mounting groove 2033 is opened at the bottom of the inner wall of the storage box 2032. The limiting ring plate 2031 is bolted to the top of the surface of the storage box 2032. The surface of the limiting ring plate 2031 contacts the inner wall of the limiting groove 2022. By setting the reaction component 203, the limiting ring plate 2031 can increase the stability of the storage box 2032 when it is placed in the limiting groove 2022. The storage box 2032 can temporarily store the seed crystals to facilitate the crystallization processing of the ivermectin crude solution. The mounting groove 2033 can support and limit the heating component 204, so that the heating component 204 can perform auxiliary heating on the seed crystals and improve the efficiency of the crystallization processing.
[0057] like Fig.10As shown, the heating component 204 includes a heat conducting plate 2041, a heat conducting ring 2042 and a heater 2043. The heat conducting plate 2041 is clamped on the inner wall of the mounting groove 2033, the heat conducting ring 2042 is welded on both sides of the inner wall of the heat conducting plate 2041, and the heater 2043 is bolted to the bottom of the heat conducting plate 2041. The bottom of the heater 2043 passes through the bottom of the storage box 2032 and is bolted to the storage box 2032. By setting the heating component 204, the heater 2043 can convert electrical energy into thermal energy after being powered on and started, and then transfer the thermal energy to the heat conducting plate 2041. The heat conducting plate 2041 can transfer the thermal energy to the heat conducting ring 2042. The heat conducting plate 2041 and the heat conducting ring 2042 can transfer the heat to the ivermectin crude solution, thereby increasing the efficiency of the ivermectin crude solution and the seed crystallization processing.
[0058] Brief description of the use process: First, put the seed crystal into the storage box 2032, then put the storage box 2032 into the limit card slot 2022, and put the limit frame 2021 into the limit box 2011 along the limit slide 2012 until the closing plate 2023 contacts and closes the access slot 2013, and then the ivermectin crude solution that has completed the stirring process is transported to the storage box 2032, and then the crystallization mechanism 2 is powered on and started, and the heater 2043 will convert the electrical energy into The heat energy is then transferred to the heat conducting plate 2041, the heat conducting plate 2041 transfers the heat to the heat conducting ring 2042, the heat conducting plate 2041 and the heat conducting ring 2042 transfer the heat to the ivermectin crude solution, the ivermectin crude solution and the seed crystals gradually produce a crystallization reaction due to the heat, until the ivermectin crude solution and the seed crystals completely complete the crystallization reaction, the limiting frame 221 can be taken out from the access slot 2013, and the prepared ivermectin can be taken out.
[0059] This specific embodiment is merely an explanation of the present invention and is not a limitation of the present invention. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed. However, as long as they are within the scope of the claims of the present invention, they are protected by the patent law.
Claims
1. A highly efficient antiparasitic ivermectin preparation device, comprising a preparation mechanism (1) and a crystallization mechanism (2), characterized in that: The preparation mechanism (1) comprises a storage component (101), a feeding component (102) and a stirring component (103); the feeding component (102) is connected to the rear side of the top of the storage component (101); the stirring component (103) is bolted to the top of the storage component (101); the crystallization mechanism (2) comprises a limiting component (201), a replacement component (202), a reaction component (203) and a heating component (204); the limiting component (201) is bolted to the bottom of the storage component (101); the replacement component (202) is clamped to the inner wall of the limiting component (201); the reaction component (203) is clamped to the inner wall of the replacement component (202); and the heating component (204) is bolted to the inner wall of the reaction component (203); The storage assembly (101) comprises a storage tank (1011), a support ring (1012) and an exhaust fan (1013), wherein the support ring (1012) is bolted to the top of the storage tank (1011), and the exhaust fan (1013) is bolted to the front side of the top of the storage tank (1011); The feeding assembly (102) comprises a feed pump (1021), a material storage pipe (1022) and a valve (1023); the valve (1023) is connected to the rear side of the top of the storage tank (1011); the material storage pipe (1022) is connected to the top of the valve (1023); and the feed pump (1021) is connected to the top of the material storage pipe (1022); The stirring assembly (103) comprises a servo motor (1031), a rotating rod (1032) and a stirring tube (1033); the servo motor (1031) is bolted to the top of the storage tank (1011); the rotating rod (1032) is bolted to the output end of the bottom of the servo motor (1031); the rotating rod (1032) penetrates the top of the storage tank (1011) and is rotatably connected to the top of the storage tank (1011); and the stirring tube (1033) is connected to the surface of the rotating rod (1032); The limiting assembly (201) comprises a limiting box (2011), a limiting slide plate (2012) and an access slot (2013); the limiting box (2011) is bolted to the bottom of the storage tank (1011); the limiting slide plate (2012) is bolted to the front side of the inner wall and the rear side of the inner wall of the limiting box (2011); and the access slot (2013) is provided on the right side of the limiting box (2011); The replacement component (202) comprises a limit frame (2021), a limit slot (2022) and a closing plate (2023); the limit frame (2021) is arranged on the inner side of the limit box (2011); the front side and the rear side of the limit frame (2021) are slidably connected to the surface of the limit slide plate (2012); the limit slot (2022) is provided on the inner wall of the limit frame (2021); the closing plate (2023) is bolted to the right side of the limit frame (2021); and the surface of the limit frame (2021) is in contact with the access slot (2013); The reaction component (203) comprises a limiting ring plate (2031), a storage box (2032) and a mounting groove (2033); the storage box (2032) is clamped on the inner wall of the limiting clamping groove (2022); the mounting groove (2033) is formed at the bottom of the inner wall of the storage box (2032); the limiting ring plate (2031) is bolted to the top of the surface of the storage box (2032); and the surface of the limiting ring plate (2031) is in contact with the inner wall of the limiting clamping groove (2022); The heating assembly (204) comprises a heat conducting plate (2041), a heat conducting ring (2042) and a heater (2043); the heat conducting plate (2041) is clamped on the inner wall of the mounting groove (2033); the heat conducting ring (2042) is welded on both sides of the inner wall of the heat conducting plate (2041); the heater (2043) is bolted to the bottom of the heat conducting plate (2041); and the bottom of the heater (2043) passes through the bottom of the storage box (2032) and is bolted to the storage box (2032); There are five stirring tubes (1033) in total, and the stirring tubes (1033) are made of stainless steel.
2. A process for preparing a highly effective antiparasitic ivermectin, using the highly effective antiparasitic ivermectin preparation device according to claim 1, characterized in that: The following steps are involved: S1. Feeding and stirring: First, the feed pump (1021) is connected to the output end of the ivermectin crude solution conveying device, and then the preparation mechanism (1) is powered on and started. When the ivermectin crude solution enters the storage tank (1011), the servo motor (1031) converts electrical energy into rotational mechanical energy, and then transmits the rotational mechanical energy to the rotating rod (1032). The rotating rod (1032) rotates with the servo motor (1031) and drives the stirring tube (1033) to rotate. The ivermectin crude solution will move with the stirring of the stirring tube (1033) and form a vortex. At the same time, the ivermectin crude solution will pass through the stirring tube (1033) when moving. After the ivermectin crude solution is stirred, the crystallization mechanism (2) is used to crystallize the ivermectin crude solution. After the ivermectin crude solution is crystallized, the exhaust fan (1013) exhausts the excess gas in the storage tank (1011) after the reaction until the preparation of ivermectin is completed. S2. Heating and crystallizing: First, a seed crystal is placed in the storage box (2032), and then the storage box (2032) is placed in the limit slot (2022), and the limit frame (2021) is placed in the limit box (2011) along the limit slide (2012) until the closing plate (223) contacts and closes the access slot (2013), and then the ivermectin crude solution that has completed the stirring process is transported to the storage box (2032), and then the crystallization mechanism (2) is powered on and started. After the power is turned on, the heater (2043) will The electrical energy is converted into thermal energy, which is then transferred to the heat conducting plate (2041). The heat conducting plate (2041) transfers the heat to the heat conducting ring (2042). The heat conducting plate (2041) and the heat conducting ring (2042) transfer the heat to the ivermectin crude solution. The ivermectin crude solution and the seed crystals gradually undergo a crystallization reaction due to the heat. After the ivermectin crude solution and the seed crystals have completely completed the crystallization reaction, the limiting frame (221) can be removed from the access slot (2013) to take out the prepared ivermectin.
Citation Information
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