A net face acne traditional Chinese medicine composition and application and gel containing the composition

Abstract

The application discloses a kind of clean face acne traditional Chinese medicine composition and application and gel containing the composition, it is related to clean face acne product technical field.The clean face acne traditional Chinese medicine composition of the application, including the following weight parts of raw material composition: 5-60 parts of forsythia suspensa extract, 3-50 parts of rhubarb extract, 2-50 parts of sophora flavescens extract, 5-60 parts of radix lithospermi extract, 1-25 parts of sparganium extract, 5-60 parts of herba violae extract, 3-50 parts of scutellaria baicalensis georgi extract, 2-50 parts of herba taraxaci extract, 2-50 parts of red root of tree peony extract, 1-25 parts of bletilla striata extract, 1-25 parts of mentha haplocalyx extract;Meanwhile, the gel containing the composition is disclosed.The application effectively realizes bacteriostasis for traditional Chinese medicine preparation, reduces skin inflammatory response, shortens acne subsidence time;Regulate sebaceous secretion, improve skin metabolism, accelerate the subsidence of acne;Redness average value before and after use and acne volume contrast is remarkable, and curative effect is exact.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of acne-removing and acne-eliminating products, and relates to an acne-removing and acne-eliminating traditional Chinese medicine composition and a gel containing the composition. BACKGROUND

[0002] Acne is a chronic inflammatory disease of the sebaceous glands, which can even develop into a serious skin problem. Acne is also known as acne, comedones and acne vulgaris, and mainly occurs on the forehead, chest, back and face, where the skin metabolism is relatively active and the sebaceous glands are more distributed. Acne is characterized by multiple morphological skin lesions. According to the degree of skin damage, the severity of acne is divided into four levels, i.e. mild (I) only exists in some comedones; moderate (II) has inflammatory papules; moderate (III) has pustules; severe (IV) has nodules and cysts.

[0003] Because of the persistence of acne, it is not easy to eliminate and is prone to recurrence. At the same time, the severity of scars increases with the persistence of acne. Not only does it cause skin damage and permanent scars, but also causes psychological trauma and other adverse effects. Studies have shown that the impact of acne extends to all aspects of people's life, mental health, etc. In short, acne is a psychosomatic disease that seriously affects work, life and health.

[0004] At present, the treatment of acne includes retinoid drugs, antibiotics and hormone drugs, etc. Studies have shown that such drugs can cause recurrence after multiple courses of treatment. The principle is to kill the microorganisms causing inflammation or remove excess sebum or accelerate skin cell regeneration, etc. In essence, it does not fundamentally solve the problem. Traditional Chinese medicine has obvious bacteriostatic, anti-inflammatory and dampness-eliminating effects. Compared with the above-mentioned drugs, it is less likely to cause bacterial resistance and can improve human immunity. Therefore, it can be used as a key research for treating acne. Although there are existing technologies that report the use of traditional Chinese medicine ingredients in cosmetics to treat acne (such as CN104127605B, CN104825674B, etc.), there is still a lack of products with definite efficacy, stable treatment and prevention effects, and no or few adverse reactions in actual application or industrialization. Therefore, the present application aims to provide an acne-removing and acne-eliminating traditional Chinese medicine composition and a gel containing the composition. SUMMARY

[0005] The present application aims to provide an acne-removing and acne-eliminating traditional Chinese medicine composition, and discloses a gel containing the composition. The present application is a pure traditional Chinese medicine component, supplemented by a medically acceptable dressing, which has better acne-removing and acne-eliminating effects, definite efficacy, stable treatment and prevention effects, and no adverse reactions.

[0006] To achieve the above technical purposes and effects, the present application is implemented by the following technical solutions:

[0007] A kind of net complexion acne-removing traditional Chinese medicine composition, including the following weight fraction of raw material composition:

[0008] Forsythia extract 5-60 parts, rhubarb extract 3-50 parts, sophora flavescens extract 2-50 parts, radix bistortae extract 5-60 parts, radix violae extract 1-25 parts, radix violae extract 5-60 parts, radix scrophulariae extract 3-50 parts, dandelion extract 2-50 parts, red root extract 2-50 parts, white and extract 1-25 parts, mint extract 1-25 parts.

[0009] Further, the net complexion acne-removing traditional Chinese medicine composition includes the following weight fraction of raw material composition: forsythia extract 20 parts, rhubarb extract 15 parts, sophora flavescens extract 10 parts, radix bistortae extract 15 parts, radix bistortae extract 5 parts, radix violae extract 20 parts, radix scrophulariae extract 10 parts, dandelion extract 10 parts, red root extract 10 parts, white and extract 5 parts, mint extract 5 parts.

[0010] Further, the net complexion acne-removing traditional Chinese medicine composition includes the following weight fraction of raw material composition: forsythia extract 40 parts, rhubarb extract 30 parts, sophora flavescens extract 30 parts, radix bistortae extract 30 parts, radix bistortae extract 10 parts, radix violae extract 40 parts, radix scrophulariae extract 20 parts, dandelion extract 20 parts, red root extract 20 parts, white and extract 10 parts, mint extract 10 parts.

[0011] Further, the net complexion acne-removing traditional Chinese medicine composition includes the following weight fraction of raw material composition: forsythia extract 10 parts, rhubarb extract 8 parts, sophora flavescens extract 5 parts, radix bistortae extract 7 parts, radix bistortae extract 3 parts, radix violae extract 10 parts, radix scrophulariae extract 5 parts, dandelion extract 5 parts, red root extract 5 parts, white and extract 3 parts, mint extract 3 parts.

[0012] The net complexion acne-removing traditional Chinese medicine composition of the application uses the following raw materials:

[0013] Forsythia extract: mainly containing forsythoside, forsythoside, oleanolic acid, etc., has antibacterial effect; has significant inhibitory effect on gram-positive and gram-negative bacteria;

[0014] Rhubarb extract: rhubarb extract has the effects of purging heat and unblocking the bowels, cooling blood and detoxifying, and removing blood stasis and unblocking channels;

[0015] Sophora flavescens extract: is an effective natural anti-inflammatory agent, can relieve inflammation and pain, and has good killing and inhibitory effect on various bacteria;It also contains rich flavonoids, which have good antioxidant effect and can help reduce the damage of free radicals to the body;

[0016] Radix Lithospermi Extract: Contains various effective ingredients such as lithospermol, lithospermol, etc., has strong antibacterial and anti-inflammatory effects, can effectively inhibit bacteria such as Propionibacterium acnes that cause acne, reduce skin inflammatory reactions, and shorten the time of acne subsidence; Contains various skin beneficial ingredients such as vitamins, minerals, and flavonoids, etc., can promote skin cell metabolism, accelerate wound healing, improve skin texture, and make it more smooth and delicate; The ingredients in Radix Lithospermi Extract can regulate sebum secretion, reduce oil accumulation, and prevent pore blockage, which helps reduce acne.

[0017] Rhizoma Sparganii Extract: Rhizoma Sparganii Extract contains various effective ingredients such as sparganin, sparganol, etc., has strong antibacterial and anti-inflammatory effects, can effectively inhibit bacteria such as Propionibacterium acnes that cause acne; Various vitamins, minerals, amino acids, polysaccharides, etc. can nourish the skin, promote skin cell metabolism, and accelerate wound healing; Can regulate sebum secretion, reduce oil accumulation, and prevent pore blockage;

[0018] Herba Violae Extract: Contains various effective ingredients such as violoside, violoside, etc., has strong antibacterial and anti-inflammatory effects; Contains various skin beneficial ingredients such as flavonoids, volatile oils, etc., can nourish the skin, promote skin cell metabolism;

[0019] Radix Scrophulariae Extract: In addition to antibacterial effects, Radix Scrophulariae Extract can promote the metabolism and excretion of toxins in the body, reducing the damage of toxins to the body; Can regulate the immune system of the body, enhance the immunity of the human body;

[0020] Herba Taraxaci Extract: Has the effects of antibacterial and anti-inflammatory, enhancing immunity, promoting blood circulation and removing blood stasis, etc.; Can promote skin and underlying microcirculation, improve skin metabolism, and accelerate the subsidence of acne;

[0021] Radix Paeoniae Rubra Extract: Has the effects of antibacterial and anti-inflammatory, clearing heat and detoxifying, regulating endocrine, and protecting the skin, among which it can regulate the endocrine system of the body, promote the stability of the internal environment of the body;

[0022] Bletilla Striata Extract: Has the effects of antibacterial and anti-inflammatory, clearing heat and detoxifying, balancing oil, and moisturizing, can regulate the secretion of skin oil, balance skin oil and moisture; Moisturizing effect can make the skin more soft and elastic;

[0023] Mentha Extract: Has the effects of inhibiting inflammation, controlling oil and astringency, refreshing and soothing, and improving skin toughness; Can promote skin cell regeneration, improve skin toughness and elasticity; Effectively inhibits skin inflammatory reactions, reduces redness and pain caused by acne.

[0024] For the acne-removing traditional Chinese medicine composition of the present application, traditional Chinese medicine believes that acne is caused by the heat of the lung and stomach, and the heat and toxin block the blood and qi, and the blood stasis in the meridians and skin. Therefore, the composition is used for clearing heat and resolving toxin, and removing blood stasis. The important components play the roles of clearing heat and resolving toxin, removing blood stasis, and inhibiting the growth of propionibacterium acnes.

[0025] The monarch drug is composed of forsythia, radix scrophulariae and radix et rhizoma rhei. Forsythia has the effects of clearing heat and resolving toxin, removing swelling and knot, and dispersing wind and heat. Radix scrophulariae has the effects of clearing heat and resolving toxin, and removing blood stasis. Radix et rhizoma rhei has the effects of clearing heat and resolving toxin, removing blood stasis, and removing swelling and knot. Therefore, the three drugs have the effects of clearing heat and resolving toxin, and removing blood stasis.

[0026] The minister drug is composed of herba violae, herba pteridis and radix paeoniae rubra. Herba violae has the effects of clearing heat and resolving toxin, and removing blood stasis. Herba pteridis has the effects of clearing heat and resolving toxin, and removing blood stasis. Radix paeoniae rubra has the effects of clearing heat and resolving toxin, and removing blood stasis. Therefore, the three drugs have the effects of clearing heat and resolving toxin, and removing blood stasis.

[0027] The assistant drug is composed of rhizoma sparganii, rhizoma bletillae and radix sophorae flavescentis. Rhizoma sparganii has the effects of removing blood stasis, removing stagnation, and removing blood stasis. Rhizoma bletillae has the effects of removing blood stasis, removing stagnation, and removing blood stasis. Radix sophorae flavescentis has the effects of clearing heat and resolving toxin, and removing blood stasis. The two drugs have the effects of removing blood stasis, removing stagnation, and removing blood stasis. The two drugs are used to assist the monarch drug in removing blood stasis, removing stagnation, and removing blood stasis.

[0028] The minister drug is composed of herba violae, herba pteridis and radix paeoniae rubra. Herba violae has the effects of clearing heat and resolving toxin, and removing blood stasis. Herba pteridis has the effects of clearing heat and resolving toxin, and removing blood stasis. Radix paeoniae rubra has the effects of clearing heat and resolving toxin, and removing blood stasis. Therefore, the three drugs have the effects of clearing heat and resolving toxin, and removing blood stasis.

[0029] Another object of the present application is to disclose an acne-removing traditional Chinese medicine product, which comprises the acne-removing traditional Chinese medicine composition and a medically acceptable auxiliary.

[0030] The product includes, but is not limited to, gel, ointment, emulsion, mask, cream, and essence.

[0031] Another object of the present invention is to provide an acne-removing gel containing a traditional Chinese medicine composition for acne treatment, wherein the acne-removing gel comprises the following raw materials in parts by weight: 0.5-30% of the above-mentioned traditional Chinese medicine composition for acne treatment, 0.5-5% of 1,3-propanediol, 1-5% of glycerin, 1-5% of panthenol, 0.5-5% of butylene glycol, 0.1-5% of 1,2-hexanediol, 0.1-1% of p-hydroxyacetophenone, 0.1-2% of carbomer, 0.1-1% of raspberry ketone, 1-5% of aminomethylpropanol, 1-5% of glycolic acid, 0.5-5% of PEG-60 hydrogenated castor oil, 0.5-5% of glyceryl caprylate, 1-10% of ethylhexylglycerin, 0.1-1% of sodium benzoate, and 70-80% of water.

[0032] Furthermore, the acne-clearing gel comprises the following raw materials in parts by weight: 5% acne-clearing herbal composition, 1% 1,3-propanediol, 1.5% glycerin, 2% panthenol, 1% butylene glycol, 0.8% 1,2-hexanediol, 0.2% p-hydroxyacetophenone, 0.5% carbomer, 0.5% raspberry ketone, 3% aminomethylpropanol, 1.5% glycolic acid, 2% PEG-60 hydrogenated castor oil, 1% glyceryl caprylate, 2.5% ethylhexylglycerin, 0.5% sodium benzoate, and 77% water.

[0033] Another objective of this invention is to provide a method for preparing an acne-removing gel containing a traditional Chinese medicine composition for acne treatment, the preparation method comprising:

[0034] S1: Prepare a traditional Chinese medicine composition for acne treatment according to the specified proportions for later use;

[0035] S2: Select 1,3-propanediol, glycerin, panthenol, butylene glycol, 1,2-hexanediol, p-hydroxyacetophenone, carbomer, raspberry ketone, aminomethylpropanol, glycolic acid, PEG-60 hydrogenated castor oil, glyceryl caprylate, ethylhexylglycerin, sodium benzoate and water in the following proportions for later use.

[0036] S3: Add the active ingredients, thickener ingredients, and regulator ingredients from the raw materials to the matrix (water) in sequence according to the process;

[0037] S4: Mix all ingredients thoroughly and stir until a homogeneous mixture is formed;

[0038] S5: Heat the mixture to a certain temperature to promote the reaction or shaping, and then cool it to room temperature or low temperature;

[0039] S6: Sterilization and packaging.

[0040] The beneficial effects of this invention are as follows:

[0041] Compared with the prior art, the acne-clearing herbal composition of the present invention is based on herbal extracts. Through synergistic effects, it can achieve antibacterial properties, reduce skin inflammation, and shorten the acne-clearing time; it can regulate sebum secretion, reduce oil accumulation, and prevent pore blockage; it can promote microcirculation in and under the skin, improve skin metabolism, and accelerate acne-clearing; and it can regulate the body's endocrine system and promote the stability of the body's internal environment.

[0042] At the same time, it is green and healthy, natural and non-irritating, effectively inhibits bacteria, and soothes skin redness, inflammation and other discomforts; it is also free of antibiotics, hormones and salicylic acid, and can improve acne problems caused by excessive sebum secretion; the curative effect is definite, the treatment and prevention effects are stable, and there are no adverse reactions.

[0043] This invention discloses an acne-removing gel containing a traditional Chinese medicine composition for acne treatment, supplemented with medically acceptable excipients. Testing showed that after 3 days of continuous use, the average redness level significantly decreased compared to the baseline (P<0.01), with a reduction rate of 13.56%; after 7 days of continuous use, the average redness level significantly decreased compared to the baseline (P<0.01), with a reduction rate of 16.26%; and after 14 days of continuous use, the average redness level significantly decreased compared to the baseline (P<0.01), with a reduction rate of 14.98%.

[0044] After 3 days of continuous use of the gel of this invention, the volume of pimples decreased significantly compared with the baseline value (P<0.01), with a reduction rate of 42.20%; after 7 days of continuous use, the volume of pimples decreased significantly compared with the baseline value (P<0.01), with a reduction rate of 68.20%; and after 14 days of continuous use, the volume of pimples decreased significantly compared with the baseline value (P<0.01), with a reduction rate of 82.75%.

[0045] After 14 days of continuous use, 88.24% of the participants found the product easily absorbed, 91.18% found it comfortable to use, 82.35% found it refreshing and non-sticky, and 91.18% found it generally pleasant to use on the skin.

[0046] 91.18% of the participants felt that the number of pimples improved significantly after using the product;

[0047] 91.18% of the test subjects felt that the product could improve the redness and swelling of acne-prone skin;

[0048] 91.18% of the participants felt that the product had a good overall acne-removing effect, 94.12% of the participants felt that the product was gentle and non-irritating, and 88.24% of the participants were generally satisfied with the product.

[0049] In summary, the product has remarkable acne-removing and skin-whitening effects when the gel is used continuously for 3 days, 7 days, and 14 days.

[0050] Of course, implementing any product of the present application does not necessarily require all the advantages described above to be achieved simultaneously. BRIEF DESCRIPTION OF DRAWINGS

[0051] Figure 1 Actual photo of acne-removing effect change of subject No. 26 for the embodiment of the present application;

[0052] Figure 2 Schematic diagram of acne volume change of subject No. 26 for the embodiment of the present application;

[0053] Figure 3 Schematic diagram of average redness change of subject No. 26 for the embodiment of the present application;

[0054] Figure 4 Actual photo of acne-removing effect change of subject No. 8 for the embodiment of the present application;

[0055] Figure 5 Schematic diagram of acne volume change of subject No. 8 for the embodiment of the present application;

[0056] Figure 6 Schematic diagram of average redness change of subject No. 8 for the embodiment of the present application;

[0057] Figure 7 Actual photo of acne-removing effect change of subject No. 12 for the embodiment of the present application;

[0058] Figure 8 Schematic diagram of acne volume change of subject No. 12 for the embodiment of the present application;

[0059] Figure 9 Schematic diagram of average redness change of subject No. 12 for the embodiment of the present application;

[0060] Figure 10 Actual photo of acne-removing effect change of subject No. 20 for the embodiment of the present application;

[0061] Figure 11 Schematic diagram of acne volume change of subject No. 20 for the embodiment of the present application;

[0062] Figure 12 Schematic diagram of average redness change of subject No. 20 for the embodiment of the present application; DETAILED DESCRIPTION

[0063] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the present application will be described in detail below with reference to the accompanying drawings.

[0064] The application will be described in connection with the specific embodiments below:

[0065] Example 1

[0066] A purifying acne-removing traditional Chinese medicine composition comprises the following raw materials in parts by weight:

[0067] 20 parts of forsythia suspensa extract, 15 parts of rhubarb extract, 10 parts of sophora flavescens extract, 15 parts of radix lithospermi extract, 5 parts of sparganium stoloniferum extract, 20 parts of radix violae extract, 10 parts of radix scrophulariae extract, 10 parts of herba taraxaci extract, 10 parts of radix paeoniae rubra extract, 5 parts of bletilla striata extract, and 5 parts of mentha haplocalyx extract.

[0068] Example 2

[0069] A purifying acne-removing traditional Chinese medicine composition comprises the following raw materials in parts by weight:

[0070] 40 parts of forsythia suspensa extract, 30 parts of rhubarb extract, 30 parts of sophora flavescens extract, 30 parts of radix lithospermi extract, 10 parts of sparganium stoloniferum extract, 40 parts of radix violae extract, 20 parts of radix scrophulariae extract, 20 parts of herba taraxaci extract, 20 parts of radix paeoniae rubra extract, 10 parts of bletilla striata extract, and 10 parts of mentha haplocalyx extract.

[0071] Example 3

[0072] A purifying acne-removing traditional Chinese medicine composition comprises the following raw materials in parts by weight:

[0073] 10 parts of forsythia suspensa extract, 8 parts of rhubarb extract, 5 parts of sophora flavescens extract, 7 parts of radix lithospermi extract, 3 parts of sparganium stoloniferum extract, 10 parts of radix violae extract, 5 parts of radix scrophulariae extract, 5 parts of herba taraxaci extract, 5 parts of radix paeoniae rubra extract, 3 parts of bletilla striata extract, and 3 parts of mentha haplocalyx extract.

[0074] Example 4

[0075] A purifying acne-removing traditional Chinese medicine product comprises the purifying acne-removing traditional Chinese medicine composition and a medically acceptable auxiliary;

[0076] The product includes but is not limited to gel, ointment, emulsion, mask, cream, and essence.

[0077] Example 5

[0078] A kind of acne gel containing acne-removing traditional Chinese medicine composition, the acne-removing traditional Chinese medicine composition includes the following weight fraction of raw material composition: the acne-removing traditional Chinese medicine composition 0.5-30%, 1, 3-propanediol 0.5-5%, glycerol 1-5%, panthenol 1-5%, butanediol 0.5-5%, 1, 2-hexanediol 0.1-5%, p-hydroxyacetophenone 0.1-1%, carbomer 0.1-2%, raspberry ketone 0.1-1%, aminomethyl propanol 1-5%, glycolic acid 1-5%, PEG-60 hydrogenated castor oil 0.5-5%, glyceryl caprylate 0.5-5%, ethyl hexyl glycerin 1-10%, sodium benzoate 0.1-1%, water 70-80%.

[0079] In the embodiment, the following raw material ratio and process are selected to prepare the acne-removing traditional Chinese medicine composition:

[0080] The acne-removing traditional Chinese medicine composition includes the following weight fraction of raw material composition: acne-removing traditional Chinese medicine composition 5%, 1, 3-propanediol 1%, glycerol 1.5%, panthenol 2%, butanediol 1%, 1, 2-hexanediol 0.8%, p-hydroxyacetophenone 0.2%, carbomer 0.5%, raspberry ketone 0.5%, aminomethyl propanol 3%, glycolic acid 1.5%, PEG-60 hydrogenated castor oil 2%, glyceryl caprylate 1%, ethyl hexyl glycerin 2.5%, sodium benzoate 0.5%, water 77%;

[0081] The acne-removing traditional Chinese medicine composition is prepared according to the raw material ratio of any one of embodiments 1-3, and the traditional Chinese medicine extract is prepared by using the existing mature process.

[0082] The preparation method includes:

[0083] S1: prepare the acne-removing traditional Chinese medicine composition according to the proportion for standby;

[0084] S2: select 1, 3-propanediol, glycerol, panthenol, butanediol, 1, 2-hexanediol, p-hydroxyacetophenone, carbomer, raspberry ketone, aminomethyl propanol, glycolic acid, PEG-60 hydrogenated castor oil, glyceryl caprylate, ethyl hexyl glycerin, sodium benzoate and water according to the proportion for standby;

[0085] S3: according to the process, the active ingredients, thickening agent ingredients and adjusting agent ingredients in the raw materials are sequentially added into the base (water);

[0086] S4: fully mix and stir the ingredients to form a homogeneous mixture;

[0087] S5: heat the mixture to a certain temperature to promote the reaction or shaping, and then cool to room temperature or low temperature;

[0088] S6: sterilize and package.

[0089] The acne-removing gel containing the net color acne-removing traditional Chinese medicine composition prepared by the embodiment of the present application has obtained the national efficacy type cosmetic record, at the same time, is sent to a detection agency for detailed detection, passes through the human skin patch project, the acne-removing efficacy project detection, and the specific detection content and results are as follows:

[0090] 1. Test design

[0091] Self-control, after the subject cleanses the face, in the standard environment (temperature 20-22 DEG C, humidity 40-60 %), sit for 30 min, 3D skin imaging analyzer Antera-3D analyzes the average value of acne volume / flushing, recorded as D0, the subject returns to test after 3 days, 7 days, 14 days of using the product, respectively recorded as D3, D7, D14, and fills in the self-evaluation questionnaire at D14;

[0092] Test time: March 31, 2023-April 24, 2023;

[0093] Environmental conditions: the test environmental conditions meet the requirements of the scheme design;

[0094] Test site: face;

[0095] Test index: average value of flushing, acne volume; test instrument: Antera-3D software analysis; time point: 4 times (D0, D3, D7, D14);

[0096] The test flow is arranged as shown in Table 1:

[0097]

[0098] Product use method:

[0099] After cleaning the skin, apply the acne-removing gel, the acne diameter area is about 1 cm, completely cover, 10-15 seconds dry, then use skin care products, 3 times a day, once in the morning, noon and evening, thick at night;

[0100] Data processing and statistical analysis

[0101] Judgment standard

[0102] Before and after using the product, if any parameter of the average value of the test area flushing and acne volume presents significant improvement, it indicates that the test material has acne-removing effect, otherwise it does not have acne-removing effect;

[0103] 2. Test results

[0104] Sample completion: a total of 34 subjects were recruited, and finally 34 subjects completed the test, including 29 females and 5 males, with an average age of 29.35±5.12 years, meeting the subject volunteer selection criteria;

[0105] The redness average value descriptive statistics results are shown in Table 2 below:

[0106]

[0107] The redness average value changes are shown in Table 3 below:

[0108]

[0109]

[0110] Redness average value: the average value of redness of the skin, the greater the value, the higher the degree of redness of the skin.

[0111] The redness average value statistical analysis results are shown in Table 4 below:

[0112]

[0113] After continuous use for 3 days, the redness average value on D3 was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 13.56%; after continuous use for 7 days, the redness average value was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 16.26%; after continuous use for 14 days, the redness average value was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 14.98%;

[0114] The acne volume descriptive statistics results are shown in Table 5 below:

[0115]

[0116]

[0117] The acne volume changes are shown in Table 6 below:

[0118]

[0119] Index explanation: acne volume: the volume of acne, the greater the value, the greater the volume of acne;

[0120] The acne volume statistical analysis results are shown in Table 7 below:

[0121]

[0122] After continuous use of the gel of the present application for 3 days, the acne volume was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 42.20%; after continuous use for 7 days, the acne volume was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 68.20%; after continuous use for 14 days, the acne volume was significantly decreased (P<0.01) compared with the base value, with a decrease rate of 82.75%;

[0123] The following statistics were compiled based on a questionnaire survey to assess the participants' satisfaction with various product indicators over a 14-day period:

[0124] After 14 days of continuous use, 88.24% of the participants found the product easily absorbed, 91.18% found it comfortable to use, 82.35% found it refreshing and non-sticky, and 91.18% found it generally pleasant to use on the skin.

[0125] 91.18% of the participants felt that the number of pimples improved significantly after using the product;

[0126] 91.18% of the test subjects felt that the product could improve the redness and swelling of acne-prone skin;

[0127] 91.18% of the participants felt that the product had a good overall acne-removing effect, 94.12% of the participants felt that the product was gentle and non-irritating, and 88.24% of the participants were generally satisfied with the product.

[0128] In summary, after continuous use of the gel of this invention for 3, 7, and 14 days, the product has significant acne-removing and skin-clearing effects.

[0129] Typical subject case:

[0130] Case 1:

[0131] Subject 26, such as Figure 1 As shown, Figure 1 The images shown in the middle are actual photos of subject number 26 on days 0, 3, 7, and 14.

[0132] like Figure 2 The figures shown are schematic diagrams illustrating the changes in pimple volume in subject 26 on days 0, 3, 7, and 14.

[0133] like Figure 3 The figures shown are schematic diagrams illustrating the changes in the average redness of subject number 26 on days 0, 3, 7, and 14.

[0134] Case 2:

[0135] Subject 8, such as Figure 4 As shown, Figure 4 The images shown in the middle are actual photos of subject 8 taken on days 0, 3, 7, and 14.

[0136] like Figure 5 The figures shown are schematic diagrams illustrating the changes in pimple volume in subject 8 on days 0, 3, 7, and 14.

[0137] like Figure 6 The figures shown are schematic diagrams illustrating the changes in the average redness of subject 8 on D0, D3, D7, and D14.

[0138] Case 3:

[0139] Subject 12, as shown in Figure 7 , the real photo of subject 12 at D0, D3, D7, D14, respectively; Figure 7

[0140] As shown in Figure 8 , the volume change diagram of acne of subject 12 at D0, D3, D7, D14, respectively;

[0141] As shown in Figure 9 , the average value change diagram of redness of subject 12 at D0, D3, D7, D14, respectively;

[0142] Case 5:

[0143] Subject 20, as shown in Figure 10 , the real photo of subject 20 at D0, D3, D7, D14, respectively; Figure 10

[0144] As shown in Figure 11 , the volume change diagram of acne of subject 20 at D0, D3, D7, D14, respectively;

[0145] As shown in Figure 12 , the average value change diagram of redness of subject 20 at D0, D3, D7, D14, respectively;

[0146] The acne-removing gel containing the acne-removing traditional Chinese medicine composition of the embodiment has a significant decrease (P<0.01) in the average value of redness compared with the base value after 3 days of continuous use of the gel of the present application, with a decrease rate of 13.56%; the average value of redness has a significant decrease (P<0.01) compared with the base value after 7 days of continuous use, with a decrease rate of 16.26%; the average value of redness has a significant decrease (P<0.01) compared with the base value after 14 days of continuous use, with a decrease rate of 14.98%;

[0147] The acne-removing gel containing the acne-removing traditional Chinese medicine composition of the embodiment has a significant decrease (P<0.01) in the volume of acne compared with the base value after 3 days of continuous use of the gel of the present application, with a decrease rate of 42.20%; the volume of acne has a significant decrease (P<0.01) compared with the base value after 7 days of continuous use, with a decrease rate of 68.20%; the volume of acne has a significant decrease (P<0.01) compared with the base value after 14 days of continuous use, with a decrease rate of 82.75%;

[0148] ​​The preferred embodiments of the application disclosed above are only to facilitate the elucidation of the application. The preferred embodiments do not describe all the details of the application and limit the application to the specific embodiments described. Many modifications and variations to the preferred embodiments are possible in light of the above teachings. The embodiments were chosen and described in order to explain the principles of the application and its practical application and to allow others skilled in the art to understand the application and to implement it in various embodiments. The application is limited only by the claims and their full scope and equivalents.

Claims

1. A traditional Chinese medicine composition for clearing and removing acne, characterized in that: It is composed of the following raw materials in parts by weight: 5-60 parts of Forsythia suspensa extract, 3-50 parts of Rheum palmatum extract, 2-50 parts of Sophora flavescens extract, 5-60 parts of Lithospermum erythrorhizon extract, 1-25 parts of Sparganium stoloniferum extract, 5-60 parts of Viola yedoensis extract, 3-50 parts of Scutellaria baicalensis extract, 2-50 parts of Taraxacum mongolicum extract, 2-50 parts of Paeonia lactiflora extract, 1-25 parts of Bletilla striata extract, and 1-25 parts of Mentha haplocalyx extract. ​ 2. The purifying acne traditional Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 20 parts forsythia extract, 15 parts rhubarb extract, 10 parts sophora flavescens extract, 15 parts gromwell root extract, 5 parts sparganium extract, 20 parts violet extract, 10 parts scutellaria baicalensis extract, 10 parts dandelion extract, 10 parts red peony root extract, 5 parts bletilla striata extract, and 5 parts peppermint extract.

3. The netian acne-removing traditional Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 40 parts forsythia extract, 30 parts rhubarb extract, 30 parts sophora flavescens extract, 30 parts gromwell root extract, 10 parts sparganium extract, 40 parts violet extract, 20 parts scutellaria baicalensis extract, 20 parts dandelion extract, 20 parts red peony root extract, 10 parts bletilla striata extract, and 10 parts peppermint extract.

4. The purifying acne traditional Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 10 parts forsythia extract, 8 parts rhubarb extract, 5 parts sophora flavescens extract, 7 parts gromwell root extract, 3 parts sparganium extract, 10 parts violet extract, 5 parts scutellaria baicalensis extract, 5 parts dandelion extract, 5 parts red peony root extract, 3 parts bletilla striata extract, and 3 parts peppermint extract.

5. The use of the acne-removing traditional Chinese medicine composition according to any one of claims 1-4 in the preparation of acne-removing products.

6. A skin clearing acne product characterized by: The product is composed of the acne-removing traditional Chinese medicine composition according to any one of claims 1-4 and medically acceptable excipients.

7. The clarifying acne product of claim 6, wherein: The products mentioned include gels, ointments, lotions, masks, creams, and serums.

8. A gel for removing acne containing a Chinese medicine composition for removing acne, characterized in that: The acne-clearing gel is composed of the following ingredients in parts by weight: 0.5-30% of the acne-clearing traditional Chinese medicine composition according to any one of claims 1-4, 0.5-5% of 1,3-propanediol, 1-5% of glycerin, 1-5% of panthenol, 0.5-5% of butylene glycol, 0.1-5% of 1,2-hexanediol, 0.1-1% of p-hydroxyacetophenone, 0.1-2% of carbomer, 0.1-1% of raspberry ketone, 1-5% of aminomethylpropanol, 1-5% of glycolic acid, 0.5-5% of PEG-60 hydrogenated castor oil, 0.5-5% of glyceryl caprylate, 1-10% of ethylhexylglycerin, 0.1-1% of sodium benzoate, and 70-80% of water.

9. The acne-removing gel containing the pure-color acne-removing traditional Chinese medicine composition according to claim 8, characterized in that: It is composed of the following ingredients in parts by weight: 5% of a traditional Chinese medicine composition for acne treatment, 1,3-propanediol, 1.5% glycerin, 2% panthenol, 1% butylene glycol, 0.8% 1,2-hexanediol, 0.2% p-hydroxyacetophenone, 0.5% carbomer, 0.5% raspberry ketone, 3% aminomethylpropanol, 1.5% glycolic acid, 2% PEG-60 hydrogenated castor oil, 1% glyceryl caprylate, 2.5% ethylhexylglycerin, 0.5% sodium benzoate, and 77% water.

10. The method for preparing the acne-removing gel containing the acne-removing traditional Chinese medicine composition of claim 9, characterized in that: The preparation method includes: S1: Prepare a traditional Chinese medicine composition for acne treatment according to the specified proportions for later use; S2: proportionally select 1,3-propanediol, glycerol, panthenol, butanediol, 1,2-hexanediol, p-hydroxyacetophenone, carbomer, raspberry ketone, aminomethyl propanol, glycolic acid, PEG-60 hydrogenated castor oil, glyceryl caprylate, ethylhexyl glycerin, sodium benzoate and water for use; S3: according to the process, sequentially add the net color acne-removing traditional Chinese medicine composition, 1,3-propanediol, glycerol, panthenol, butanediol, 1,2-hexanediol, p-hydroxyacetophenone, carbomer, raspberry ketone, aminomethyl propanol, glycolic acid, PEG-60 hydrogenated castor oil, glyceryl caprylate, ethylhexyl glycerin, sodium benzoate in water; S4: mix and stir the ingredients thoroughly to form a homogeneous mixture; S5: heat the mixture to a certain temperature to promote reaction or shaping, and then cool to room temperature or low temperature; S6: sterilization and packaging.

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