Capsule drying and granulation integrated equipment and use method thereof

Abstract

The present invention belongs to the technical field of pharmaceutical production equipment, in particular to an integrated capsule drying and granulating equipment and a method for using the same. Aiming at the problem that in the prior art, drying and granulating are performed in different equipment, medicines are exposed to external bacteria and are affected by moisture, and some medicine powder is scattered on the surface of medicine particles, the following scheme is proposed, which comprises: a fixed table, a granulating box and a holding box are respectively provided above and below the fixed table, a feeding pipe for injecting materials is provided on both sides of the granulating box, and a fixed cylinder fixedly connected to the top of the holding box is fixedly penetrated in the fixed table; in the present invention, drying and granulating are performed in the same equipment, so that the medicine particles are prevented from being contaminated by external bacteria and being affected by moisture, and the heat in the hot air can be repeatedly utilized in the process of drying and granulating the raw materials, so as to maximize the utilization of heat energy and the drying of the medicine particles, and in addition, the medicine powder scattered on the surface of the medicine particles can be recycled in the process of drying and granulating, so as to avoid waste.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical production equipment, and in particular to a capsule drying and granulating integrated equipment and a use method thereof. Background Art

[0002] Encapsulation technology refers to the encapsulation of solids, liquids or gases in tiny and sealed capsules. When sealing the solid in the capsule, the pharmaceutical powder needs to be dried and then granulated, and then sealed into the capsule at the later stage.

[0003] However, the following problems still exist in the prior art when drying and granulating pharmaceutical raw materials:

[0004] 1. Drying and granulation need to be carried out in different equipment respectively. Therefore, when the medicine is transported between different equipment, it is easy for the medicine to come into contact with external bacteria, and the dried medicine is affected by moisture in the air and becomes damp again;

[0005] 2. During the granulation process, some powder will fall from the surface of the granules and float in the air, causing waste of powder.

[0006] In response to the above problems, the present invention document proposes a capsule drying and granulation integrated device and a method for using the same. Summary of the Invention

[0007] The present invention provides an integrated capsule drying and granulating device and a method for using the same, which solves the drawbacks in the prior art that drying and granulating are performed in different devices, the medicines are exposed to external bacteria and moisture, and some powder is spilled from the surface of the medicine particles.

[0008] The present invention provides the following technical solutions:

[0009] A capsule drying and granulation integrated device comprises: a fixed platform, a granulation box and a storage box are respectively provided above and below the fixed platform, a feeding pipe for injecting material is provided on both sides of the granulation box, and a fixed cylinder is fixedly passed through the fixed platform and fixedly connected to the top of the storage box;

[0010] An extrusion plate for extruding raw materials is slidably connected in the granulation box, two second slides are fixedly connected to the top of the extrusion plate, and the tops of the second slides slide through the granulation box, and the second slides are used to close the feed pipes respectively. A cylinder is fixedly connected to the top of the granulation box, and the output shaft of the cylinder extends into the granulation box and is fixedly connected to the top of the extrusion plate;

[0011] A granulation structure is provided in the granulation box and is used to granulate the raw materials;

[0012] A collecting structure is provided on the top of the fixed platform for collecting the medicine powder scattered on the medicine particles;

[0013] The drying structure is arranged on one side of the containing box and is used to dry the raw materials in the granulating box and the granules after granulation.

[0014] In one possible design, the granulation structure includes a plurality of second through holes arranged at the bottom of the granulation box, the bottom inner wall of the granulation box is rotatably connected to a rotating disk, and a plurality of second through holes are provided in the rotating disk that cooperate with the first through holes, one side of the granulation box is sealed and slidably penetrated by a trapezoidal pin that cooperates with the extrusion plate, the bottom of the trapezoidal pin is fixedly connected to a vertical rod, the side of the vertical rod close to the granulation box is fixedly connected to a plurality of first tension springs, and the other end of the first tension spring is fixedly connected to the granulation box, the bottom end of the vertical rod is fixedly connected to a sliding rod that slides through the granulation box, a groove is provided in the rotating disk, and the top inner wall and the bottom inner wall of the groove are both provided with guide grooves, and the top and bottom of the sliding rod are fixedly connected to the guide The guide column and the guide column slide in the guide groove, and the bottom inner wall of the holding box is rotatably connected with a rotating shaft, and the top of the rotating shaft is rotatably connected to the bottom of the granulation box. The outer wall fixed sleeve of the rotating shaft is provided with a scraper for scraping the medicine extruded in the second through hole, and the outer wall of the rotating shaft is provided with a reciprocating threaded section; the trapezoidal pin and the sliding rod are pushed downward by the extrusion plate to move outward, and the sliding rod drives the rotating disk to rotate a certain angle through the cooperation of the guide column and the guide groove. At this time, the second through hole is aligned with the first through hole. As the extrusion plate moves downward, the extrusion plate squeezes the compacted medicine raw materials through the second through hole and the first through hole to the bottom, and the rotating shaft drives the scraper to rotate to scrape the medicine particles extruded from the bottom of the granulation box, thereby preliminarily completing the granulation operation.

[0015] In one possible design, the collecting structure includes a filter box fixedly connected to one side of the top of the fixed platform, a fixed ring is slidably connected inside the filter box, a plurality of second tension springs are fixedly connected to the top of the fixed ring, the top of the second tension spring is fixedly connected to the inner wall of the filter box through a protrusion, and a dust filter is provided in the fixed ring for filtering the medicine powder; in the process of the medicine particles falling from the bottom of the granulation box onto the screen plate, a small amount of medicine powder scattered on the surface of the medicine particles enters the filter box under the action of hot air, and at this time the dust filter can filter the medicine powder to prevent the medicine powder from overflowing to the outside with the hot air.

[0016] In a possible design, the drying structure includes a hot air blower arranged on one side of the holding box, and the air outlet of the hot air blower extends into the holding box, a screen plate is rotatably connected in the holding box, a spiral guide roller for increasing the drying time of the granules is fixedly connected in the fixed cylinder, and the top end of the rotating shaft rotates and passes through the spiral guide roller, a plurality of circular holes for drying the granules are distributed on the spiral guide roller, the outer wall of the fixed cylinder is fixedly connected to a collecting concave plate, the outer wall of the collecting concave plate is fixedly connected to a closed ring, and the inner wall of the closed ring is fixedly connected to the bottom outer wall of the granulation box, the closed ring is connected to the filter box through a first air duct, and the granulation box The outer wall fixed sleeve is provided with a hollow notch ring for drying the raw materials inside the granulation box, and the hollow notch ring is connected to the filter box through a second air duct; the hot air blower blows hot air into the holding box, and the hot air enters the fixed cylinder to dry the granules on the spiral guide roller, and the hot air can also blow the scattered powder on the granules into the filter box for filtration. In addition, the hot air passes through the filter box and enters the hollow notch ring. At this time, the hot air is blown to the heat-conducting ceramic plate through the exhaust port, and the medicine raw materials in the fixed table can be preliminarily dried through the heat-conducting ceramic plate. After the hot air heats the heat-conducting ceramic plate, it is blown to the feed pipe through the short air guide pipe to preheat the medicine raw materials in the feed pipe.

[0017] In one possible design, a plurality of exhaust ports are provided on a side of the hollow notch ring close to the granulation box, a plurality of heat-conducting ceramic plates are provided in the granulation box, and the heat-conducting ceramic plates correspond to the exhaust ports, and two short air pipes are provided in the granulation box, and the short air pipes are located below the feed pipe and above the hollow notch ring; hot air is blown toward the heat-conducting ceramic plates through the exhaust ports. Since the heat-conducting ceramic plates are made of silicon carbide, the thermal conductivity of the heat-conducting ceramic plates is relatively high. The heat-conducting ceramic plates can be used to preliminarily dry the pharmaceutical raw materials in the fixed table, and the hot air heats the heat-conducting ceramic plates and then blows toward the feed pipe through the short air pipes to preheat the pharmaceutical raw materials in the feed pipe.

[0018] In a possible design, the holding box is provided with a discharge port on a side away from the hot air blower, and a closing plate for closing the discharge port is slidably connected to the inner wall of one side of the holding box, and the bottom of the closing plate is fixedly connected to a plurality of springs, and the bottom ends of the springs are fixedly connected to the bottom inner wall of the holding box, and the top of the closing plate touches the bottom of the sieve plate, and the bottom inner wall of the holding box is fixedly connected to a fixing plate, and one side of the fixing plate is slidably connected to a first slide, and one side of the first slide is fixedly connected to a nut, and the nut is threadedly connected to the rotating shaft through a reciprocating thread section, and the bottom of the sieve plate is fixedly connected to a fixing rod, and the side of the fixing rod close to the rotating shaft is rotatably connected to a rotating plate that cooperates with the nut. A limit plate is fixedly connected to one side of the fixed rod to limit the rotating plate, and a clearance hole is provided in the screen plate for making way for the rotating shaft; the nut moves up and down under the action of the reciprocating threaded section, and when the nut moves down and cooperates with the rotating plate, the screen plate can rotate counterclockwise, and the dried medicine particles accumulated on the screen plate are discharged to the outside along the screen plate and the discharge port to facilitate the staff to collect the medicine particles. In addition, when the screen plate rotates clockwise, the screen plate drives the fixed rod to rotate, thereby causing the rotating plate to disengage from the nut. At this time, the screen plate is reset under the elastic force of the spring, and the closing plate re-closes the discharge port, thereby preventing the medicine powder in the box from overflowing from the discharge port, and preventing hot air from being discharged to the outside through the discharge port to cause heat loss.

[0019] In a possible design, an air filter is fixedly connected to one side of the storage box, and the air filter is connected to the air outlet of the hot air blower. A pipe for filtering the hot air is provided in the air filter.

[0020] In one possible design, a pull rope is fixedly connected to the bottom of one side of the fixed ring, and the bottom end of the pull rope extends into the holding box and is fixedly connected to the top side of the sieve plate, and the bottom of the fixed platform is fixedly connected to two guide wheels for guiding the pull rope; when the sieve plate rotates clockwise to discharge, the sieve plate pulls the fixed ring downward through the pull rope, and when the sieve plate is reset, the fixed ring is also reset upward under the action of the second tension spring, and the fixed ring and the dust filter vibrate, which can shake off the powder filtered on the dust filter.

[0021] In one possible design, a horizontal plate is fixedly connected to the holding box, and the top of the horizontal plate is fixedly connected to the bottom of the fixed plate, the outer wall of the rotating shaft is fixedly connected to a plurality of trapezoidal plates for lifting dust, and the bottom of the trapezoidal plates is slidably connected to the bottom inner wall of the holding box, and the trapezoidal plates are located below the horizontal plate; when the rotating shaft rotates, the trapezoidal plates are driven to rotate rapidly, and the inclined surfaces of the trapezoidal plates can lift the powder that falls on the bottom inner wall of the holding box, so that the powder is scattered into the filter box under the action of hot air.

[0022] The method for using the capsule drying and granulation integrated equipment comprises the following steps:

[0023] S1. Inject the mixed prepared pharmaceutical raw materials into the granulation box through the feed pipe, start the hot air blower, and blow hot air into the holding box. At this time, the discharge port is closed by the closing plate, and the hot air passes through the fixed cylinder and the filter box into the hollow gap ring. At this time, the hot air is blown to the heat-conducting ceramic plate through the exhaust port. Since the heat-conducting ceramic plate is made of silicon carbide, the thermal conductivity of the heat-conducting ceramic plate is relatively high. The heat-conducting ceramic plate can preliminarily dry the pharmaceutical raw materials in the fixed table, and the hot air heats the heat-conducting ceramic plate and then blows to the feed pipe through the short air pipe to preheat the pharmaceutical raw materials in the feed pipe;

[0024] S2, start the cylinder to drive the extrusion plate to move downward, the extrusion plate drives the second slide plate to move downward, and the feed pipe can be blocked by the second slide plate. At this time, the air guide short tube preheats the pharmaceutical raw materials in the feed pipe. When the extrusion plate moves down a certain distance, the pharmaceutical raw materials are compacted. Then the extrusion plate continues to move downward, and the trapezoidal pin and the sliding rod are pushed outward by the extrusion plate. The sliding rod drives the rotating disk to rotate a certain angle through the cooperation of the guide column and the guide groove. At this time, the second through hole is aligned with the first through hole. As the extrusion plate moves downward, the extrusion plate squeezes the compacted pharmaceutical raw materials to the bottom through the second through hole and the first through hole. Then start the drive motor (not shown in the figure) to drive the rotating shaft to rotate, and the rotating shaft drives the scraper to rotate to scrape the pharmaceutical particles extruded from the bottom of the granulation box, and the granulation operation is preliminarily completed.

[0025] S3. The medicine pellets enter the fixed cylinder through the collecting concave plate. The spiral guide roller can increase the time the medicine pellets spend in the fixed cylinder. Since the spiral guide roller is provided with multiple circular holes, the upward hot air in the fixed cylinder can further dry the medicine pellets until they fall onto the sieve plate. In addition, when the medicine pellets fall onto the sieve plate from the bottom of the granulation box, a small amount of medicine powder scattered on the surface of the medicine pellets enters the filter box under the action of the hot air. At this time, the dust filter can filter the medicine powder to prevent it from being scattered to the outside with the hot air.

[0026] S4. When the shaft rotates to scrape the medicine particles, the nut moves back and forth under the action of the reciprocating threaded section. When the nut moves down and cooperates with the rotating plate, the sieve plate can rotate counterclockwise. The dried medicine particles accumulated on the sieve plate are discharged to the outside along the sieve plate and the discharge port, which is convenient for the staff to collect the medicine particles and seal the medicine particles into capsules in the subsequent process. In addition, when the sieve plate rotates clockwise, the sieve plate drives the fixed rod to rotate, thereby causing the rotating plate to disengage from the nut. At this time, the sieve plate is reset under the elastic force of the spring, and the sealing plate re-seals the discharge port, thereby preventing the medicine powder in the box from overflowing from the discharge port and preventing the hot air from being discharged to the outside through the discharge port to cause heat loss.

[0027] S5. In addition, when the sieve plate rotates clockwise to discharge, the sieve plate pulls the fixed ring downward through the pull rope. When the sieve plate is reset, the fixed ring is also reset upward under the action of the second tension spring. The fixed ring and the dust filter vibrate, which can shake off the powder filtered on the dust filter, making it easier for the staff to collect the powder through the outlet (not shown in the figure) and reuse it;

[0028] S6. When the shaft rotates, the trapezoidal plate is driven to rotate rapidly. The inclined surface of the trapezoidal plate can lift the powder that falls on the inner wall of the bottom of the storage box, so that the powder is scattered into the filter box under the action of hot air.

[0029] It should be understood that the foregoing general description and the following detailed description are exemplary only and are not restrictive of the invention.

[0030] In the present invention, a fixing ring is slidably connected in the filter box, and a plurality of second tension springs are fixedly connected to the top of the fixing ring. A pull rope is fixedly connected to the bottom of one side of the fixing ring, and the bottom end of the pull rope is fixedly connected to one side of the top of the sieve plate. In the process of the medicine particles falling from the bottom of the granulation box onto the sieve plate, a small amount of medicine powder scattered on the surface of the medicine particles enters the filter box under the action of hot air. At this time, the dust filter can filter the medicine powder to prevent the medicine powder from overflowing to the outside with the hot air. In addition, when the sieve plate rotates clockwise to discharge the material, the sieve plate drives the dust filter to vibrate through the pull rope, and can shake off the medicine powder filtered on the dust filter, which is convenient for collecting and reusing the medicine powder in the later stage.

[0031] In the present invention, the bottom inner wall of the granulation box is rotatably connected to a rotating disk, and a plurality of second through holes matching the first through holes are provided in the rotating disk, a trapezoidal pin is sealingly and slidably penetrated on one side of the granulation box, a sliding rod is slidably penetrated on one side of the granulation box, the top and bottom of the sliding rod are fixedly connected to a guide column, and the guide column and the guide groove are slidably matched; the extrusion plate moves downward to push the trapezoidal pin and the sliding rod to move outward, and the sliding rod drives the rotating disk to rotate a certain angle, and the extrusion plate squeezes the compacted pharmaceutical raw materials through the second through hole and the first through hole to the bottom, and the pharmaceutical particles extruded from the bottom of the granulation box are scraped off by the scraper, thereby preliminarily completing the granulation operation;

[0032] In the present invention, a spiral guide roller is fixedly connected to the fixed cylinder, and a plurality of circular holes for drying the medicine particles are distributed on the spiral guide roller. The outer wall of the collecting concave plate is fixedly connected to a closed ring, and the inner wall of the closed ring is fixedly connected to the outer wall of the bottom of the granulation box. The outer wall of the granulation box is fixedly sleeved with a hollow gap ring for drying the raw materials inside the granulation box; the hot air dries the medicine particles on the spiral guide roller, and the hot air can also blow the medicine powder scattered on the medicine particles into the filter box for filtration. In addition, the hot air enters the hollow gap ring through the filter box. At this time, the hot air is blown to the heat-conducting ceramic plate through the exhaust port, and the medicine raw materials in the fixed table can be preliminarily dried through the heat-conducting ceramic plate. The hot air preheats the medicine raw materials in the feed pipe through the short air guide tube.

[0033] In the present invention, a closing plate is slidably connected to the inner wall of one side of the containing box, and a fixed plate is fixedly connected to the inner wall of the bottom of the containing box. The fixed plate is slidably connected to a nut through a first slide plate, and the nut is threadably connected to the rotating shaft through a reciprocating threaded section, and the side of the fixing rod close to the rotating shaft is rotatably connected to a rotating plate; the nut moves back and forth up and down under the action of the reciprocating threaded section, and when the nut moves down and cooperates with the rotating plate to make the sieve plate rotate counterclockwise, the dried medicine particles are discharged to the outside along the sieve plate, and the sieve plate drives the fixed rod to rotate, and the rotating plate and the nut are out of contact. At this time, the sieve plate is reset under the elastic force of the spring, and the closing plate re-closes the discharge port, thereby preventing the medicine powder in the containing box from overflowing from the discharge port, and preventing hot air from being discharged to the outside through the discharge port, causing heat loss.

[0034] In the present invention, drying and granulation are carried out in the same equipment, so that the medicine particles are prevented from being contaminated by external bacteria and being affected by moisture. In addition, the heat in the hot air can be used multiple times in the process of drying and granulating the raw materials, so as to maximize the use of thermal energy and the drying of the medicine particles. In addition, in the process of drying and granulating, the medicine powder scattered on the surface of the medicine particles can be recycled to avoid waste. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 A schematic diagram of the three-dimensional structure from a first perspective of a capsule drying and granulation integrated device provided by an embodiment of the present invention;

[0036] Figure 2 A schematic diagram of the three-dimensional structure from a second perspective of a capsule drying and granulation integrated device provided by an embodiment of the present invention;

[0037] Figure 3 A schematic diagram of a three-dimensional cross-sectional structure of a capsule drying and granulation integrated device provided by an embodiment of the present invention;

[0038] Figure 4 A schematic diagram of a three-dimensional cross-sectional structure of a granulation box of a capsule drying and granulation integrated device provided by an embodiment of the present invention, as viewed from a first perspective;

[0039] Figure 5 A schematic diagram of a three-dimensional exploded structure of a guide groove and a guide column of a capsule drying and granulation integrated device provided by an embodiment of the present invention;

[0040] Figure 6 A schematic diagram of a three-dimensional cross-sectional structure of a heat-conducting ceramic plate and a hollow notched ring of a capsule drying and granulation integrated device provided by an embodiment of the present invention;

[0041] Figure 7 A schematic three-dimensional cross-sectional view of a collecting concave plate, a fixing cylinder and a containing box of a capsule drying and granulating integrated device provided by an embodiment of the present invention;

[0042] Figure 8 A schematic diagram of a three-dimensional cross-sectional structure of a nut, a fixed rod, and a rotating plate of a capsule drying and granulating integrated device provided by an embodiment of the present invention;

[0043] Figure 9 A schematic three-dimensional cross-sectional view of a filter box of a capsule drying and granulation integrated equipment provided by an embodiment of the present invention;

[0044] Figure 10 A schematic diagram of a three-dimensional cross-sectional structure of a granulation box of a capsule drying and granulation integrated device provided by an embodiment of the present invention, viewed from a second perspective;

[0045] Figure 11 This is an enlarged structural diagram of point A of the capsule drying and granulation integrated equipment provided by the present invention;

[0046] Figure 12 This is a partial front and cross-sectional structural diagram of a containing box of a capsule drying and granulating integrated device provided in Example 2 of the present invention.

[0047] Reference numerals:

[0048] 1. Fixed table; 2. Granulating box; 3. Container; 4. Feed pipe; 5. Heat-conducting ceramic plate; 6. Extrusion plate; 7. Cylinder; 8. First through hole; 9. Rotating plate; 10. Second through hole; 11. Trapezoidal pin; 12. Vertical rod; 13. First tension spring; 14. Sliding rod; 15. Groove; 16. Guide groove; 17. Guide column; 18. Rotating shaft; 19. Scraper; 20. Fixed cylinder; 21. Collecting concave plate; 22. Spiral guide roller; 23. Hot air blower; 24. Discharge port; 25. Screen plate; 26. Closing plate; 27. Spring; 28. Fixed plate; 29. ​​First slide; 30. Reciprocating threaded section; 31. Nut; 32. Fixed rod; 33. Rotating plate; 34. Limiting plate; 35. Closing ring; 36. First air duct; 37. Filter box; 38. Fixed ring; 39. Second tension spring; 40. Dust filter; 41. Second air duct; 42. Hollow notched ring; 43. Exhaust port; 44. Pull rope; 45. Guide wheel; 46. Pipe; 47. Air filter; 48. Make way hole; 49. Short air duct; 50. Second slide; 51. Horizontal plate; 52. Trapezoidal plate. DETAILED DESCRIPTION

[0049] The embodiments of the present invention are described below with reference to the accompanying drawings.

[0050] In the description of the embodiments of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms, "connection", and "installation" should be understood in a broad sense. For example, "connection" can be a detachable connection or a non-detachable connection; it can be a direct connection or an indirect connection through an intermediate medium. In addition, "communication" can be a direct connection or an indirect connection through an intermediate medium. Here, "fixed" means that the two are connected to each other and the relative position relationship after connection remains unchanged. The directional terms mentioned in the embodiments of the present invention, such as "inside", "outside", "top", "bottom", etc., are only reference to the directions of the accompanying drawings. Therefore, the directional terms used are for better and clearer explanation and understanding of the embodiments of the present invention, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present invention.

[0051] In the embodiments of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, features defined as "first" or "second" may explicitly or implicitly include one or more of such features.

[0052] In the embodiments of the present invention, "and / or" is simply a description of the association relationship between associated objects, indicating that three possible relationships exist. For example, "A and / or B" can represent three situations: A exists alone, A and B exist simultaneously, and B exists alone. Furthermore, the character " / " in this document generally indicates that the associated objects are in an "or" relationship.

[0053] References to "one embodiment" or "some embodiments" in this specification mean that a particular feature, structure, or characteristic described in connection with that embodiment is included in one or more embodiments of the present invention. Thus, phrases such as "in one embodiment," "in some embodiments," "in other embodiments," and "in yet other embodiments" appearing in various places in this specification do not necessarily refer to the same embodiment, but rather mean "one or more, but not all, embodiments," unless otherwise specifically emphasized. The terms "including," "comprising," "having," and variations thereof mean "including but not limited to," unless otherwise specifically emphasized.

[0054] Example 1

[0055] Reference Figure 1 、 Figure 2 and Figure 3 The present embodiment is a capsule drying and granulation integrated equipment, comprising: a fixed platform 1, a granulation box 2 and a holding box 3 are respectively provided above and below the fixed platform 1, a feeding pipe 4 for injecting material is provided on both sides of the granulation box 2, a fixed cylinder 20 fixedly connected to the top of the holding box 3 is fixedly passed through the fixed platform 1; an extrusion plate 6 for extruding raw materials is slidably connected in the granulation box 2, the top of the extrusion plate 6 is fixedly connected to two second slides 50 by bolts, and the top of the second slide 50 slides through the granulation box 2, and the second slide 50 is used to close the feeding pipe 4 respectively, the top of the granulation box 2 is fixedly connected to a cylinder 7 by bolts, and the output shaft of the cylinder 7 extends into the granulation box 2 and is fixedly connected to the top of the extrusion plate 6 by bolts; a granulation structure is arranged in the granulation box 2 for granulating the raw materials; a collecting structure is arranged on the top of the fixed platform 1 for collecting the powder scattered on the granules; a drying structure is arranged on one side of the holding box 3 for drying the raw materials in the granulation box 2 and the granulated granules.

[0056] Reference Figure 3 、 Figure 4 and Figure 5The granulation structure includes a plurality of second through holes 10 arranged at the bottom of the granulation box 2, and a rotating disk 9 is rotatably connected to the bottom inner wall of the granulation box 2. A plurality of second through holes 10 cooperating with the first through holes 8 are provided in the rotating disk 9. A trapezoidal pin 11 cooperating with the extrusion plate 6 is sealed and slidably penetrated on one side of the granulation box 2. The bottom of the trapezoidal pin 11 is fixedly connected to a vertical rod 12 by bolts. A plurality of first tension springs 13 are fixedly connected to the side of the vertical rod 12 close to the granulation box 2, and the other end of the first tension spring 13 is fixedly connected to the granulation box 2. The bottom end of the vertical rod 12 is fixedly connected to a sliding rod 14 that slides through the granulation box 2 by bolts. A groove 15 is provided in the rotating disk 9, and the top inner wall and the bottom inner wall of the groove 15 are both provided with guide grooves 16. The top and bottom of the sliding rod 14 are fixedly connected to guide columns 17 by bolts, and the guide The column 17 slides in cooperation with the guide groove 16, and the bottom inner wall of the holding box 3 is rotatably connected with a rotating shaft 18. The top of the rotating shaft 18 is rotatably connected to the bottom of the granulation box 2. The outer wall of the rotating shaft 18 is fixedly sleeved with a scraper 19 for scraping the medicine extruded from the second through hole 10, and the outer wall of the rotating shaft 18 is provided with a reciprocating threaded section 30; the trapezoidal pin 11 and the sliding rod 14 are pushed outward by the extrusion plate 6 moving downward, and the sliding rod 14 drives the rotating disk 9 to rotate a certain angle through the cooperation of the guide column 17 and the guide groove 16. At this time, the second through hole 10 is aligned with the first through hole 8. As the extrusion plate 6 moves downward, the extrusion plate 6 squeezes the compacted pharmaceutical raw materials through the second through hole 10 and the first through hole 8 to the bottom, and the rotating shaft 18 drives the scraper 19 to rotate to scrape the pharmaceutical particles extruded from the bottom of the granulation box 2, thereby preliminarily completing the granulation operation.

[0057] Reference Figure 9 The collection structure includes a filter box 37 fixedly connected to one side of the top of the fixed platform 1 by bolts, and a fixing ring 38 is slidably connected inside the filter box 37. A plurality of second tension springs 39 are fixedly connected to the top of the fixing ring 38. The top of the second tension spring 39 is fixedly connected to the inner wall of the filter box 37 through a protrusion. A dust filter 40 for filtering the medicine powder is provided in the fixing ring 38; in the process of the medicine particles falling from the bottom of the granulating box 2 onto the sieve plate 25, a small amount of medicine powder scattered on the surface of the medicine particles enters the filter box 37 under the action of hot air. At this time, the dust filter 40 can filter the medicine powder to prevent the medicine powder from overflowing to the outside with the hot air.

[0058] Reference Figure 6 、 Figure 7 、 Figure 10 and Figure 11The drying structure includes a hot air blower 23 arranged on one side of the holding box 3, and the air outlet of the hot air blower 23 extends into the holding box 3, a sieve plate 25 is rotatably connected in the holding box 3, a spiral guide roller 22 for increasing the drying time of the granules is fixedly connected in the fixed cylinder 20, and the top end of the rotating shaft 18 rotates and penetrates the spiral guide roller 22, and a plurality of circular holes for drying the granules are distributed on the spiral guide roller 22, the outer wall of the fixed cylinder 20 is fixedly connected to the collecting concave plate 21 by bolts, the outer wall of the collecting concave plate 21 is fixedly connected to the closing ring 35 by bolts, and the inner wall of the closing ring 35 is fixedly connected to the outer wall of the bottom of the granulating box 2 by bolts, the closing ring 35 is connected to the filter box 37 by a first air guide pipe 36, and the outer wall of the granulating box 2 The fixed sleeve is provided with a hollow notch ring 42 for drying the raw materials inside the granulation box 2, and the hollow notch ring 42 is connected to the filter box 37 through a second air duct 41; the hot air blower 23 blows hot air into the holding box 3, and the hot air enters the fixed cylinder 20 to dry the granules on the spiral guide roller 22, and the hot air can also blow the scattered powder on the granules into the filter box 37 for filtration. In addition, the hot air passes through the filter box 37 and enters the hollow notch ring 42. At this time, the hot air is blown to the heat-conducting ceramic plate 5 through the exhaust port 43, and the medicine raw materials in the fixed table 1 can be preliminarily dried through the heat-conducting ceramic plate 5. After the hot air heats the heat-conducting ceramic plate 5, it is blown to the feed pipe 4 through the air guide short pipe 49 to preheat the medicine raw materials in the feed pipe 4.

[0059] Reference Figure 6 and Figure 11 , a plurality of exhaust ports 43 are provided on the side of the hollow notch ring 42 close to the granulation box 2, a plurality of heat-conducting ceramic plates 5 are provided in the granulation box 2, and the heat-conducting ceramic plates 5 correspond to the exhaust ports 43, and two air-guiding short pipes 49 are provided in the granulation box 2, and the air-guiding short pipes 49 are located below the feed pipe 4 and above the hollow notch ring 42; the hot air is blown to the heat-conducting ceramic plates 5 through the exhaust ports 43. Since the heat-conducting ceramic plates 5 are made of silicon carbide, the thermal conductivity of the heat-conducting ceramic plates 5 is relatively high. The heat-conducting ceramic plates 5 can be used to preliminarily dry the pharmaceutical raw materials in the fixed table 1, and the hot air heats the heat-conducting ceramic plates 5 and then blows to the feed pipe 4 through the air-guiding short pipes 49 to preheat the pharmaceutical raw materials in the feed pipe 4.

[0060] Reference Figure 7 and Figure 8, a discharge port 24 is provided on the side of the holding box 3 away from the hot air blower 23, and a closing plate 26 for closing the discharge port 24 is slidably connected to the inner wall of one side of the holding box 3, and a plurality of springs 27 are fixedly connected to the bottom of the closing plate 26, and the bottom end of the spring 27 is fixedly connected to the bottom inner wall of the holding box 3, and the top of the closing plate 26 touches the bottom of the sieve plate 25, and the bottom inner wall of the holding box 3 is fixedly connected to a fixing plate 28 by bolts, and a first slide plate 29 is slidably connected to one side of the fixing plate 28, and a nut 31 is fixedly connected to one side of the first slide plate 29 by bolts, and the nut 31 is threadedly connected to the rotating shaft 18 through a reciprocating threaded section 30, and the bottom of the sieve plate 25 is fixedly connected to a fixing rod 32 by bolts, and the fixing rod 32 is rotatably connected to the side of the rotating shaft 18 with a rotating plate 33 cooperating with the nut 31, and one side of the fixing rod 32 The sieve plate 25 is fixedly connected with a limit plate 34 for limiting the rotating plate 33 by bolts, and a clearance hole 48 is provided in the sieve plate 25 for making way for the rotating shaft 18; the nut 31 moves up and down under the action of the reciprocating threaded section 30, and when the nut 31 moves down and cooperates with the rotating plate 33 to make the sieve plate 25 rotate counterclockwise, the dried medicine particles accumulated on the sieve plate 25 are discharged to the outside along the sieve plate 25 and the discharge port 24 to facilitate the staff to collect the medicine particles. In addition, when the sieve plate 25 rotates clockwise, the sieve plate 25 drives the fixing rod 32 to rotate, thereby causing the rotating plate 33 to disengage from the nut 31. At this time, the sieve plate 25 is reset under the elastic force of the spring 27, and the closing plate 26 re-closes the discharge port 24, which prevents the medicine powder in the holding box 3 from overflowing from the discharge port 24 and preventing the hot air from being discharged to the outside through the discharge port 24, causing heat loss.

[0061] Reference Figure 7 An air filter 47 is fixedly connected to one side of the storage box 3 by bolts, and the air filter 47 is connected to the air outlet of the hot air blower 23. A pipe 46 for filtering the hot air is provided in the air filter 47.

[0062] Reference Figure 3 and Figure 7 A pull rope 44 is fixedly connected to the bottom of one side of the fixing ring 38, and the bottom end of the pull rope 44 extends into the holding box 3 and is fixedly connected to the top side of the sieve plate 25. The bottom of the fixed platform 1 is fixedly connected to two guide wheels 45 for guiding the pull rope 44; when the sieve plate 25 rotates clockwise for discharging, the sieve plate 25 pulls the fixing ring 38 downward through the pull rope 44. When the sieve plate 25 is reset, the fixing ring 38 is also reset upward under the action of the second tension spring 39. The fixing ring 38 and the dust filter 40 vibrate, which can shake off the powder filtered on the dust filter 40.

[0063] Example 2

[0064] Reference Figure 1 、 Figure 2 and Figure 3The present embodiment is a capsule drying and granulation integrated equipment, comprising: a fixed platform 1, a granulation box 2 and a holding box 3 are respectively provided above and below the fixed platform 1, a feeding pipe 4 for injecting material is provided on both sides of the granulation box 2, a fixed cylinder 20 fixedly connected to the top of the holding box 3 is fixedly passed through the fixed platform 1; an extrusion plate 6 for extruding raw materials is slidably connected in the granulation box 2, the top of the extrusion plate 6 is fixedly connected to two second slides 50 by bolts, and the top of the second slide 50 slides through the granulation box 2, and the second slide 50 is used to close the feeding pipe 4 respectively, the top of the granulation box 2 is fixedly connected to a cylinder 7 by bolts, and the output shaft of the cylinder 7 extends into the granulation box 2 and is fixedly connected to the top of the extrusion plate 6 by bolts; a granulation structure is arranged in the granulation box 2 for granulating the raw materials; a collecting structure is arranged on the top of the fixed platform 1 for collecting the powder scattered on the granules; a drying structure is arranged on one side of the holding box 3 for drying the raw materials in the granulation box 2 and the granulated granules.

[0065] Reference Figure 3 、 Figure 4 and Figure 5 The granulation structure includes a plurality of second through holes 10 arranged at the bottom of the granulation box 2, and a rotating disk 9 is rotatably connected to the bottom inner wall of the granulation box 2. A plurality of second through holes 10 cooperating with the first through holes 8 are provided in the rotating disk 9. A trapezoidal pin 11 cooperating with the extrusion plate 6 is sealed and slidably penetrated on one side of the granulation box 2. The bottom of the trapezoidal pin 11 is fixedly connected to a vertical rod 12 by bolts. A plurality of first tension springs 13 are fixedly connected to the side of the vertical rod 12 close to the granulation box 2, and the other end of the first tension spring 13 is fixedly connected to the granulation box 2. The bottom end of the vertical rod 12 is fixedly connected to a sliding rod 14 that slides through the granulation box 2 by bolts. A groove 15 is provided in the rotating disk 9, and the top inner wall and the bottom inner wall of the groove 15 are both provided with guide grooves 16. The top and bottom of the sliding rod 14 are fixedly connected to guide columns 17 by bolts, and the guide The column 17 slides in cooperation with the guide groove 16, and the bottom inner wall of the holding box 3 is rotatably connected with a rotating shaft 18. The top of the rotating shaft 18 is rotatably connected to the bottom of the granulation box 2. The outer wall of the rotating shaft 18 is fixedly sleeved with a scraper 19 for scraping the medicine extruded from the second through hole 10, and the outer wall of the rotating shaft 18 is provided with a reciprocating threaded section 30; the trapezoidal pin 11 and the sliding rod 14 are pushed outward by the extrusion plate 6 moving downward, and the sliding rod 14 drives the rotating disk 9 to rotate a certain angle through the cooperation of the guide column 17 and the guide groove 16. At this time, the second through hole 10 is aligned with the first through hole 8. As the extrusion plate 6 moves downward, the extrusion plate 6 squeezes the compacted pharmaceutical raw materials through the second through hole 10 and the first through hole 8 to the bottom, and the rotating shaft 18 drives the scraper 19 to rotate to scrape the pharmaceutical particles extruded from the bottom of the granulation box 2, thereby preliminarily completing the granulation operation.

[0066] Reference Figure 9The collection structure includes a filter box 37 fixedly connected to one side of the top of the fixed platform 1 by bolts, and a fixing ring 38 is slidably connected inside the filter box 37. A plurality of second tension springs 39 are fixedly connected to the top of the fixing ring 38. The top of the second tension spring 39 is fixedly connected to the inner wall of the filter box 37 through a protrusion. A dust filter 40 for filtering the medicine powder is provided in the fixing ring 38; in the process of the medicine particles falling from the bottom of the granulating box 2 onto the sieve plate 25, a small amount of medicine powder scattered on the surface of the medicine particles enters the filter box 37 under the action of hot air. At this time, the dust filter 40 can filter the medicine powder to prevent the medicine powder from overflowing to the outside with the hot air.

[0067] Reference Figure 6 、 Figure 7 、 Figure 10 and Figure 11 The drying structure includes a hot air blower 23 arranged on one side of the holding box 3, and the air outlet of the hot air blower 23 extends into the holding box 3, a sieve plate 25 is rotatably connected in the holding box 3, a spiral guide roller 22 for increasing the drying time of the granules is fixedly connected in the fixed cylinder 20, and the top end of the rotating shaft 18 rotates and penetrates the spiral guide roller 22, and a plurality of circular holes for drying the granules are distributed on the spiral guide roller 22, the outer wall of the fixed cylinder 20 is fixedly connected to the collecting concave plate 21 by bolts, the outer wall of the collecting concave plate 21 is fixedly connected to the closing ring 35 by bolts, and the inner wall of the closing ring 35 is fixedly connected to the outer wall of the bottom of the granulating box 2 by bolts, the closing ring 35 is connected to the filter box 37 by a first air guide pipe 36, and the outer wall of the granulating box 2 The fixed sleeve is provided with a hollow notch ring 42 for drying the raw materials inside the granulation box 2, and the hollow notch ring 42 is connected to the filter box 37 through a second air duct 41; the hot air blower 23 blows hot air into the holding box 3, and the hot air enters the fixed cylinder 20 to dry the granules on the spiral guide roller 22, and the hot air can also blow the scattered powder on the granules into the filter box 37 for filtration. In addition, the hot air passes through the filter box 37 and enters the hollow notch ring 42. At this time, the hot air is blown to the heat-conducting ceramic plate 5 through the exhaust port 43, and the medicine raw materials in the fixed table 1 can be preliminarily dried through the heat-conducting ceramic plate 5. After the hot air heats the heat-conducting ceramic plate 5, it is blown to the feed pipe 4 through the air guide short pipe 49 to preheat the medicine raw materials in the feed pipe 4.

[0068] Reference Figure 6 and Figure 11, a plurality of exhaust ports 43 are provided on the side of the hollow notch ring 42 close to the granulation box 2, a plurality of heat-conducting ceramic plates 5 are provided in the granulation box 2, and the heat-conducting ceramic plates 5 correspond to the exhaust ports 43, and two air-guiding short pipes 49 are provided in the granulation box 2, and the air-guiding short pipes 49 are located below the feed pipe 4 and above the hollow notch ring 42; the hot air is blown to the heat-conducting ceramic plates 5 through the exhaust ports 43. Since the heat-conducting ceramic plates 5 are made of silicon carbide, the thermal conductivity of the heat-conducting ceramic plates 5 is relatively high. The heat-conducting ceramic plates 5 can be used to preliminarily dry the pharmaceutical raw materials in the fixed table 1, and the hot air heats the heat-conducting ceramic plates 5 and then blows to the feed pipe 4 through the air-guiding short pipes 49 to preheat the pharmaceutical raw materials in the feed pipe 4.

[0069] Reference Figure 7 and Figure 8 , a discharge port 24 is provided on the side of the holding box 3 away from the hot air blower 23, and a closing plate 26 for closing the discharge port 24 is slidably connected to the inner wall of one side of the holding box 3, and a plurality of springs 27 are fixedly connected to the bottom of the closing plate 26, and the bottom end of the spring 27 is fixedly connected to the bottom inner wall of the holding box 3, and the top of the closing plate 26 touches the bottom of the sieve plate 25, and the bottom inner wall of the holding box 3 is fixedly connected to a fixing plate 28 by bolts, and a first slide plate 29 is slidably connected to one side of the fixing plate 28, and a nut 31 is fixedly connected to one side of the first slide plate 29 by bolts, and the nut 31 is threadedly connected to the rotating shaft 18 through a reciprocating threaded section 30, and the bottom of the sieve plate 25 is fixedly connected to a fixing rod 32 by bolts, and the fixing rod 32 is rotatably connected to the side of the rotating shaft 18 with a rotating plate 33 cooperating with the nut 31, and one side of the fixing rod 32 The sieve plate 25 is fixedly connected with a limit plate 34 for limiting the rotating plate 33 by bolts, and a clearance hole 48 is provided in the sieve plate 25 for making way for the rotating shaft 18; the nut 31 moves up and down under the action of the reciprocating threaded section 30, and when the nut 31 moves down and cooperates with the rotating plate 33 to make the sieve plate 25 rotate counterclockwise, the dried medicine particles accumulated on the sieve plate 25 are discharged to the outside along the sieve plate 25 and the discharge port 24 to facilitate the staff to collect the medicine particles. In addition, when the sieve plate 25 rotates clockwise, the sieve plate 25 drives the fixing rod 32 to rotate, thereby causing the rotating plate 33 to disengage from the nut 31. At this time, the sieve plate 25 is reset under the elastic force of the spring 27, and the closing plate 26 re-closes the discharge port 24, which prevents the medicine powder in the holding box 3 from overflowing from the discharge port 24 and preventing the hot air from being discharged to the outside through the discharge port 24, causing heat loss.

[0070] Reference Figure 7 An air filter 47 is fixedly connected to one side of the storage box 3 by bolts, and the air filter 47 is connected to the air outlet of the hot air blower 23. A pipe 46 for filtering the hot air is provided in the air filter 47.

[0071] Reference Figure 3 and Figure 7A pull rope 44 is fixedly connected to the bottom of one side of the fixing ring 38, and the bottom end of the pull rope 44 extends into the holding box 3 and is fixedly connected to the top side of the sieve plate 25. The bottom of the fixed platform 1 is fixedly connected to two guide wheels 45 for guiding the pull rope 44; when the sieve plate 25 rotates clockwise for discharging, the sieve plate 25 pulls the fixing ring 38 downward through the pull rope 44. When the sieve plate 25 is reset, the fixing ring 38 is also reset upward under the action of the second tension spring 39. The fixing ring 38 and the dust filter 40 vibrate, which can shake off the powder filtered on the dust filter 40.

[0072] Reference Figure 12 A horizontal plate 51 is fixedly connected to the holding box 3 by bolts, and the top of the horizontal plate 51 is fixedly connected to the bottom of the fixed plate 28 by bolts, and the outer wall of the rotating shaft 18 is fixedly connected to a plurality of trapezoidal plates 52 for raising dust by bolts, and the bottom of the trapezoidal plates 52 is slidably connected to the bottom inner wall of the holding box 3, and the trapezoidal plates 52 are located below the horizontal plate 51; when the rotating shaft 18 rotates, the trapezoidal plates 52 are driven to rotate rapidly, and the inclined surface of the trapezoidal plates 52 can raise the powder that falls on the bottom inner wall of the holding box 3, so that the powder is scattered into the filter box 37 under the action of hot air.

[0073] A method for using a capsule drying and granulating integrated device comprises the following steps:

[0074] S1. Inject the mixed prepared pharmaceutical raw materials into the granulation box 2 through the feed pipe 4, start the hot air blower 23, and blow hot air into the holding box 3. At this time, the discharge port 24 is closed by the closing plate 26, and the hot air passes through the fixed cylinder 20 and the filter box 37 and enters the hollow notched ring 42. At this time, the hot air is blown to the heat-conducting ceramic plate 5 through the exhaust port 43. Since the heat-conducting ceramic plate 5 is made of silicon carbide, the thermal conductivity of the heat-conducting ceramic plate 5 is relatively high. The heat-conducting ceramic plate 5 can preliminarily dry the pharmaceutical raw materials in the fixed table 1, and the hot air heats the heat-conducting ceramic plate 5 and is blown to the feed pipe 4 through the air guide short pipe 49 to preheat the pharmaceutical raw materials in the feed pipe 4;

[0075] S2, start the cylinder 7 to drive the extrusion plate 6 to move downward, and the extrusion plate 6 drives the second slide plate 50 to move downward, and the feed pipe 4 can be blocked by the second slide plate 50. At this time, the air guide short tube 49 preheats the pharmaceutical raw materials in the feed pipe 4. When the extrusion plate 6 moves down a certain distance, the compaction of the pharmaceutical raw materials is completed. Then the extrusion plate 6 continues to move downward, and the trapezoidal pin 11 and the sliding rod 14 are pushed outward by the extrusion plate 6. The sliding rod 14 drives the rotating disk 9 to rotate a certain angle through the cooperation of the guide column 17 and the guide groove 16. At this time, the second through hole 10 is aligned with the first through hole 8. As the extrusion plate 6 moves downward, the extrusion plate 6 squeezes the compacted pharmaceutical raw materials to the bottom through the second through hole 10 and the first through hole 8. Then start the drive motor (not shown in the figure) to drive the rotating shaft 18 to rotate. The rotating shaft 18 drives the scraper 19 to rotate, and the pharmaceutical particles extruded from the bottom of the granulation box 2 are scraped off, and the granulation operation is preliminarily completed;

[0076] S3. The medicine pellets pass through the collecting concave plate 21 and enter the fixed cylinder 20. The spiral guide roller 22 can increase the time the medicine pellets spend in the fixed cylinder 20. Since the spiral guide roller 22 has a plurality of circular holes, the upward hot air in the fixed cylinder 20 can further dry the medicine pellets until they fall onto the sieve plate 25. In addition, when the medicine pellets fall from the bottom of the granulating box 2 onto the sieve plate 25, a small amount of medicine powder scattered on the surface of the medicine pellets enters the filter box 37 under the action of the hot air. At this time, the dust filter 40 can filter the medicine powder to prevent it from being scattered to the outside with the hot air.

[0077] S4. When the rotating shaft 18 rotates to scrape the medicine particles, the nut 31 moves back and forth up and down under the action of the reciprocating threaded section 30. When the nut 31 moves down and cooperates with the rotating plate 33 to make the sieve plate 25 rotate counterclockwise, the dried medicine particles accumulated on the sieve plate 25 are discharged to the outside along the sieve plate 25 and the discharge port 24, which is convenient for the staff to collect the medicine particles and seal the medicine particles into the capsule in the subsequent process. In addition, when the sieve plate 25 rotates clockwise, the sieve plate 25 drives the fixing rod 32 to rotate, thereby causing the rotating plate 33 to disengage from the nut 31. At this time, the sieve plate 25 is reset under the elastic force of the spring 27, and the closing plate 26 re-closes the discharge port 24, thereby preventing the medicine powder in the holding box 3 from overflowing from the discharge port 24 and preventing the hot air from being discharged to the outside through the discharge port 24 to cause heat loss.

[0078] S5. When the sieve plate 25 rotates clockwise to discharge the material, the sieve plate 25 pulls the fixing ring 38 downward through the pull rope 44. When the sieve plate 25 is reset, the fixing ring 38 is also reset upward under the action of the second tension spring 39. The fixing ring 38 and the dust filter 40 vibrate, which can shake off the powder filtered on the dust filter 40, making it easier for the staff to collect the powder through the outlet (not shown) and reuse it later.

[0079] S6. When the rotating shaft 18 rotates, the trapezoidal plate 52 is driven to rotate rapidly. The inclined surface of the trapezoidal plate 52 can lift the medicine powder that falls on the bottom inner wall of the containing box 3, so that the medicine powder is scattered into the filter box 37 under the action of hot air.

[0080] However, as is well known to those skilled in the art, the working principles and wiring methods of the hot air blower 23 and the cylinder 7 are conventional means or common knowledge and will not be elaborated here. Those skilled in the art can make any selections according to their needs or convenience.

[0081] The above are only specific embodiments of the present invention, but the scope of protection of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present invention should be included in the scope of protection of the present invention. The embodiments of the present invention and the features therein can be combined with each other unless there is a conflict. Therefore, the scope of protection of the present invention shall be based on the scope of protection of the claims.

Claims

1. A capsule drying and granulation integrated equipment, characterized in that: include: A fixed platform (1), wherein a granulation box (2) and a storage box (3) are respectively provided above and below the fixed platform (1), a feeding pipe (4) for injecting material is provided on both sides of the granulation box (2), and a fixed cylinder (20) fixedly connected to the top of the storage box (3) is fixedly passed through the fixed platform (1); An extrusion plate (6) for extruding raw materials is slidably connected in the granulation box (2), two second slides (50) are fixedly connected to the top of the extrusion plate (6), and the tops of the second slides (50) slide through the granulation box (2), and the second slides (50) are used to respectively close the feed pipes (4). A cylinder (7) is fixedly connected to the top of the granulation box (2), and the output shaft of the cylinder (7) extends into the granulation box (2) and is fixedly connected to the top of the extrusion plate (6); A granulation structure is provided in a granulation box (2) and is used for granulating raw materials; the granulation structure comprises a plurality of first through holes (8) provided at the bottom of the granulation box (2); a rotating disk (9) is rotatably connected to the inner wall of the bottom of the granulation box (2); a plurality of second through holes (10) matching the first through holes (8) are provided in the rotating disk (9); a trapezoidal pin (11) matching the extrusion plate (6) is sealed and slidably penetrated on one side of the granulation box (2); a vertical rod (12) is fixedly connected to the bottom of the trapezoidal pin (11); a plurality of first tension springs (13) are fixedly connected to the side of the vertical rod (12) close to the granulation box (2); and the other end of the first tension spring (13) is fixedly connected to the granulation box (2); The bottom end of the granulating box (2) is fixedly connected to a sliding rod (14) that slides through the granulating box (2), a groove (15) is provided in the rotating disk (9), the top inner wall and the bottom inner wall of the groove (15) are both provided with a guide groove (16), the top and the bottom of the sliding rod (14) are fixedly connected to a guide column (17), and the guide column (17) and the guide groove (16) are slidably matched, the bottom inner wall of the holding box (3) is rotatably connected to a rotating shaft (18), the top end of the rotating shaft (18) is rotatably connected to the bottom of the granulating box (2), the outer wall of the rotating shaft (18) is fixedly provided with a scraper (19) for scraping the medicine extruded from the second through hole (10), and the outer wall of the rotating shaft (18) is provided with a reciprocating thread section (30); A collecting structure is provided on the top of the fixed platform (1) for collecting medicine powder scattered on the medicine particles; the collecting structure comprises a filter box (37) fixedly connected to one side of the top of the fixed platform (1), a fixing ring (38) is slidably connected in the filter box (37), a plurality of second tension springs (39) are fixedly connected to the top of the fixing ring (38), the top of the second tension spring (39) is fixedly connected to the inner wall of the filter box (37) through a protrusion, and a dust filter (40) is provided in the fixing ring (38) for filtering the medicine powder; A drying structure is provided on one side of the holding box (3) and is used to dry the raw materials in the granulation box (2) and the granulated medicine granules; The drying structure includes a hot air blower (23) arranged on one side of the holding box (3), and the air outlet of the hot air blower (23) extends into the holding box (3), a screen plate (25) is rotatably connected to the holding box (3), a spiral guide roller (22) for increasing the drying time of the medicine particles is fixedly connected to the fixed cylinder (20), and the top end of the rotating shaft (18) rotates and penetrates the spiral guide roller (22), and a plurality of circular holes for drying the medicine particles are distributed on the spiral guide roller (22), and the outer wall of the fixed cylinder (20) is fixedly connected to the spiral guide roller (22). A collecting concave disc (21) is provided, the outer wall of the collecting concave disc (21) is fixedly connected to a closed ring (35), and the inner wall of the closed ring (35) is fixedly connected to the outer wall of the bottom of the pelletizing box (2), the closed ring (35) and the filter box (37) are connected via a first air guide pipe (36), the outer wall of the pelletizing box (2) is fixedly sleeved with a hollow gap ring (42) for drying the raw materials inside the pelletizing box (2), and the hollow gap ring (42) and the filter box (37) are connected via a second air guide pipe (41); The storage box (3) is provided with a discharge port (24) on a side away from the hot air blower (23), and a closing plate (26) for closing the discharge port (24) is slidably connected to the inner wall of one side of the storage box (3), and a plurality of springs (27) are fixedly connected to the bottom of the closing plate (26), and the bottom ends of the springs (27) are fixedly connected to the bottom inner wall of the storage box (3), and the top of the closing plate (26) contacts the bottom of the sieve plate (25), and a fixed plate (28) is fixedly connected to the inner wall of the bottom of the storage box (3), and a first slide plate is slidably connected to one side of the fixed plate (28). (29), a nut (31) is fixedly connected to one side of the first slide plate (29), and the nut (31) is threadedly connected to the rotating shaft (18) through a reciprocating thread section (30), a fixing rod (32) is fixedly connected to the bottom of the sieve plate (25), a rotating plate (33) that cooperates with the nut (31) is rotatably connected to the side of the fixing rod (32) close to the rotating shaft (18), a limiting plate (34) that limits the rotating plate (33) is fixedly connected to one side of the fixing rod (32), and a clearance hole (48) for making way for the rotating shaft (18) is provided in the sieve plate (25).

2. The capsule drying and granulation integrated equipment according to claim 1, characterized in that: A plurality of exhaust ports (43) are provided on a side of the hollow notch ring (42) close to the pelletizing box (2), a plurality of heat-conducting ceramic plates (5) are provided in the pelletizing box (2), and the heat-conducting ceramic plates (5) correspond to the exhaust ports (43), and two short air guide tubes (49) are provided in the pelletizing box (2), and the short air guide tubes (49) are located below the feed tube (4) and above the hollow notch ring (42).

3. The capsule drying and granulation integrated equipment according to claim 2, characterized in that: An air filter (47) is fixedly connected to one side of the storage box (3), and the air filter (47) is connected to the air outlet of the hot air blower (23). A pipe (46) for filtering hot air is provided in the air filter (47).

4. The capsule drying and granulation integrated equipment according to claim 3, characterized in that: A drawstring (44) is fixedly connected to the bottom of one side of the fixing ring (38), and the bottom end of the drawstring (44) extends into the storage box (3) and is fixedly connected to the top side of the screen plate (25). The bottom of the fixing platform (1) is fixedly connected to two guide wheels (45) for guiding the drawstring (44).

5. The capsule drying and granulation integrated equipment according to claim 4, characterized in that: A transverse plate (51) is fixedly connected to the storage box (3), and the top of the transverse plate (51) is fixedly connected to the bottom of the fixed plate (28). The outer wall of the rotating shaft (18) is fixedly connected to a plurality of trapezoidal plates (52) for raising dust, and the bottom of the trapezoidal plates (52) is slidably connected to the bottom inner wall of the storage box (3), and the trapezoidal plates (52) are located below the transverse plate (51).

6. A method for using the capsule drying and granulation integrated device according to claim 5, characterized in that: The following steps are involved: S1, injecting the mixed prepared pharmaceutical raw materials into the granulation box (2) through the feed pipe (4), starting the hot air blower (23), and blowing hot air into the storage box (3). The hot air heats the heat-conducting ceramic plate (5) and then blows toward the feed pipe (4) through the air guide short pipe (49), thereby preheating the pharmaceutical raw materials in the feed pipe (4); S2, start the cylinder (7) to drive the extrusion plate (6) to move downward, and the extrusion plate (6) drives the second slide plate (50) to move downward, and the second slide plate (50) can block the feed pipe (4). At this time, the air guide short tube (49) preheats the pharmaceutical raw materials in the feed pipe (4). When the extrusion plate (6) moves down a certain distance, the compaction of the pharmaceutical raw materials is completed. Then the extrusion plate (6) continues to move downward, and the trapezoidal pin (11) and the sliding rod (14) are pushed outward by the extrusion plate (6). Then the drive motor is started to drive the rotating shaft (18) to rotate. The rotating shaft (18) drives the scraper (19) to rotate, and the pharmaceutical particles extruded from the bottom of the granulation box (2) are scraped off, and the granulation operation is preliminarily completed; S3, the medicine particles enter the fixed cylinder (20) through the collecting concave plate (21), and the time for the medicine particles to move in the fixed cylinder (20) is increased under the action of the spiral guide roller (22). Since the spiral guide roller (22) is provided with a plurality of circular holes, the upward hot air in the fixed cylinder (20) can further dry the medicine particles until the medicine particles fall onto the sieve plate (25); S4. When the rotating shaft (18) rotates to scrape off the medicine particles, the nut (31) moves back and forth up and down under the action of the reciprocating thread section (30). When the nut (31) moves downward and cooperates with the rotating plate (33), the sieve plate (25) can rotate counterclockwise. The dried medicine particles accumulated on the sieve plate (25) are discharged to the outside along the sieve plate (25) and the discharge port (24) to facilitate the collection of the medicine particles by the staff, and the medicine particles are subsequently sealed into capsules; S5. When the sieve plate (25) rotates clockwise to discharge the material, the sieve plate (25) pulls the fixing ring (38) downward through the pull rope (44). When the sieve plate (25) is reset, the fixing ring (38) is also reset upward under the action of the second tension spring (39), and the fixing ring (38) and the dust filter (40) vibrate. S6. When the rotating shaft (18) rotates, the trapezoidal plate (52) is driven to rotate rapidly. The inclined surface of the trapezoidal plate (52) can lift the powder that falls on the inner wall of the bottom of the containing box (3), so that the powder is dispersed into the filter box (37) under the action of hot air.

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