Preparation device and method of mequidone injection

Abstract

This invention discloses an apparatus and method for preparing acetylmethionine injection, relating to the field of acetylmethionine injection preparation technology. It solves the problems often encountered in acetylmethionine injection preparation devices during use, such as the mixture stagnating at the bottom of the mixing tank, residue easily accumulating at the bottom edge, leading to insufficient mixing, and material adhering to the inner wall of the mixing tank, making it difficult to remove. The apparatus and method include a mixing mechanism with a stirring tank on one side, and a stirring component movably installed inside the mixing mechanism. This invention, through the cooperation of baffles and spiral plates, allows the acetylmethionine injection to be stirred and mixed simultaneously with the materials, while also transporting the materials to the top of the mixing tank via the baffles, thus turning over the materials at the bottom to the top, preventing uneven mixing.

Description

Technical Field

[0001] This invention relates to the field of acetylmethionine injection preparation, specifically to an apparatus and method for preparing acetylmethionine injection. Background Technology

[0002] Acetylmethionine is a Western medicine preparation mainly used for diseases such as swine dysentery and bacterial enteritis caused by Treponema pallidum. Its mechanism of action is to inhibit the synthesis of deoxyribonucleic acid in bacteria, thereby achieving an antibacterial effect.

[0003] Acetylmethionine is mainly available in tablet and injection forms. Due to restrictions on the use of tablets, acetylmethionine powder products have been discontinued, and acetylmethionine injection has become its main formulation. When preparing acetylmethionine injection, specialized preparation equipment is usually used.

[0004] Existing acetylmethionine injection preparation devices, especially mixing devices, often suffer from stagnation of the liquid and powder mixture at the bottom of the mixing tank, and the material tends to adhere to the inner wall of the mixing tank, making it difficult to remove. Therefore, they do not meet the current requirements. To address this, we propose an acetylmethionine injection preparation device and method. Summary of the Invention

[0005] The purpose of this invention is to provide an apparatus and method for preparing acetylmethionine injection, in order to solve the problems mentioned in the background art, such as the acetylmethionine injection preparation apparatus, especially the mixing apparatus, often stagnating at the bottom of the mixing tank, and residues easily stagnating at the edge of the bottom of the mixing tank, resulting in insufficient mixing, and the material easily adhering to the inner wall of the mixing tank, which is difficult to remove.

[0006] To achieve the above objectives, the present invention provides the following technical solution: an apparatus for preparing acetylmethionine injection, comprising a mixing mechanism, a stirring tank on one side of the mixing mechanism, a filtering mechanism on one side of the stirring tank, an adjusting tank on one side of the filtering mechanism, and a filling mechanism on one side of the adjusting tank. The mixing mechanism, stirring tank, filtering mechanism, adjusting tank, and filling mechanism are all connected by a conveying mechanism. A rotating shaft is rotatably connected to the middle of the mixing mechanism. A stirring assembly and multiple scraping and turning assemblies are movably installed inside the mixing mechanism.

[0007] The stirring assembly includes a baffle, a spiral plate, and a T-shaped spiral groove. The spiral plate is fixedly installed on the outer surface of the rotating shaft, and the baffle is fixedly installed on the outer surface of the spiral plate. The outer surface of the baffle is provided with a T-shaped spiral groove.

[0008] Each scraping and turning assembly includes a movable block, a scraping arc rod, a T-shaped movable rod, and a turning chamber. The movable block is movably installed on the inner surface of the mixing mechanism. Scraping arc rods are fixedly installed on both sides of the movable block, and the surfaces of the scraping arc rods are in contact with the inner wall surface of the mixing mechanism. A T-shaped movable rod is movably installed at one end of the movable block facing the center of the mixing mechanism. One end of the T-shaped movable rod mates with a T-shaped spiral groove. A turning chamber is provided inside the bottom end of the movable block.

[0009] Preferably, the scraping and turning assembly further includes a telescopic groove, a compression spring, a nickel-iron alloy plate, a sliding groove, a connecting buckle, and a pushing spring. The movable block is provided with a telescopic groove at each position where the T-shaped movable rod is installed. One end of the T-shaped movable rod is movably inserted into the telescopic groove. A compression spring is provided between the inside of the telescopic groove and the left end of the T-shaped movable rod. A nickel-iron alloy plate is movably installed on the bottom surface inside the turning chamber. A sliding groove is provided on the side of the turning chamber near the mixing mechanism. One end of the nickel-iron alloy plate is slidably installed inside the sliding groove. A pushing spring is provided between the sliding groove and the nickel-iron alloy plate. A connecting buckle is fixedly installed on the end of the movable block near the inner wall surface of the mixing mechanism.

[0010] Preferably, the mixing mechanism includes a mixing tank, a feed inlet, a feeding pipe, a motor base, a servo motor, a rotating shaft, a fixing plate, a lifting groove, and a discharge pipe. The mixing tank is fixedly installed on one side of the mixing tank. A feed inlet is fixedly installed on one side of the top of the mixing tank, and a feeding pipe is fixedly installed on the other side of the top of the mixing tank. A motor base is fixedly installed at the center of the top of the mixing tank, and a servo motor is fixedly installed at the top of the motor base. A rotating shaft is movably installed at the center of the interior of the mixing tank. The output end of the servo motor is connected to the top of the rotating shaft via a coupling. Four fixing plates are fixedly installed on the inner wall surface of the mixing tank, and each fixing plate has a lifting groove on its outer surface. A discharge pipe is located near the bottom of the rear surface of the mixing tank. Electromagnets are fixedly installed near the bottom and top of the lifting groove.

[0011] Preferably, the stirring assembly further includes through holes and a conical push rod. The surface of the spiral plate is provided with multiple through holes, and a conical push rod is fixedly installed on the top surface of the baffle near the upper opening of the T-shaped spiral groove.

[0012] Preferably, both the connecting buckle and the lifting groove are T-shaped, and the connecting buckle is movably engaged inside the lifting groove.

[0013] Preferably, the bottom surface of each movable block is provided with a through hole, and the through hole is connected to the interior of the turning chamber.

[0014] Preferably, the outside of the mixing tank is movably mounted on a cooling sleeve, and a plurality of support columns are fixedly mounted on the bottom end of the cooling sleeve.

[0015] Preferably, the outer surface of the baffle is provided with multiple leakage holes near the T-shaped spiral groove, and the leakage holes are all connected to the space inside the T-shaped spiral groove near the bottom.

[0016] A method for preparing acetylmethionine injection, the method comprising the following steps:

[0017] S1. Take 10L of benzyl alcohol, 20L of ethanol and 5L of propylene glycol and add them to a mixing tank and mix them evenly to obtain a cosolvent;

[0018] S2. Pour the solubilizer and sufficient water for injection into a mixing tank, then add 50g of stabilizer and 3kg of acetylmethionine and stir to dissolve.

[0019] S3. Filter the solution obtained by stirring through the filtration mechanism in an environment of 18-26℃, and pour the filtered solution into the conditioning tank;

[0020] S4. Adjust the pH of the filtered solution to 9.5-11.0 using ethanolamine, and then sterilize it at high temperature.

[0021] S5. After the prepared acetylmethionine injection solution undergoes a qualification test, it is filled through a filling mechanism and then packaged into a product.

[0022] S6. In step S, the mixing tank, through the cooperation of baffles and spiral plates, allows the acetylmethionine injection solution to be stirred and mixed with the prepared materials. Simultaneously, the materials are transported to the top of the mixing tank via the baffles, while materials at the bottom are moved to the top, preventing uneven mixing. Furthermore, through the cooperation of the movable block and the T-shaped movable rod, the baffle rotates, bringing the T-shaped movable rod into the T-shaped spiral groove. This allows the movable block to move up and down outside the fixed plate. When the movable block rises, the material-turning chamber is filled into the mixing tank near the bottom edge. The material is placed in the container. When the T-shaped movable rod moves to the highest position with the T-shaped spiral groove, the outer surface of the T-shaped movable rod can be pushed by the conical push rod to retract the T-shaped movable rod into the telescopic groove. At this time, the movable block loses support and falls down from the top of the outer side of the fixed plate along the lifting groove. At this time, the material located inside the turning chamber will be poured out and poured back to the position above the material inside the mixing tank, thus realizing the turning operation. Through the setting of the scraping arc rod, the movable block can scrape the inner wall surface of the mixing tank through the scraping arc rod during the lifting process to prevent the material from adhering to and remaining on the inner wall surface of the mixing tank.

[0023] Compared with the prior art, the beneficial effects of the present invention are:

[0024] 1. This invention, through the combination of baffles and spiral plates, allows acetylmethionine injection to be stirred and mixed with the prepared materials through the baffles and spiral plates. At the same time, the materials can be transported to the top of the mixing tank through the baffles, while the materials at the bottom are turned to the top, thus preventing uneven mixing.

[0025] 2. This invention utilizes the cooperation of a movable block and a T-shaped movable rod to allow the baffle to rotate while simultaneously bringing the T-shaped movable rod into the interior of the T-shaped spiral groove. This allows the movable block to move up and down on the outside of the fixed plate. When the movable block is raised, the material inside the material-turning chamber near the bottom edge of the mixing tank is loaded into it. When the T-shaped movable rod moves to its highest position along with the T-shaped spiral groove, the outer surface of the T-shaped movable rod can be pushed by a conical push rod to retract the T-shaped movable rod into the telescopic groove. At this point, the movable block loses its support and descends from the top of the outside of the fixed plate along the lifting groove.

[0026] 3. This invention utilizes the cooperation of a nickel-iron alloy plate and a push spring. The elastic potential energy of the push spring can push the nickel-iron alloy plate, ensuring that the nickel-iron alloy plate keeps the bottom of the turning chamber sealed, thus preventing the liquid inside the turning chamber from leaking. Furthermore, the electromagnet attracts the nickel-iron alloy plate, causing the movable block to slide into the sliding groove as it rises and falls. This removes the seal from the bottom of the turning chamber, allowing the liquid inside to be poured out as the movable block passes the electromagnet, thus completing the turning operation of the liquid inside the mixing tank. Attached Figure Description

[0027] Figure 1 This is a schematic diagram of the structure for preparing the assembly line production of the present invention;

[0028] Figure 2 This is a schematic diagram of a half-section of the mixing tank of the present invention;

[0029] Figure 3 This is a cross-sectional front view of the mixing tank of the present invention;

[0030] Figure 4 This is a cross-sectional side view of the mixing tank of the present invention;

[0031] Figure 5 This is a top cross-sectional view of the mixing tank of the present invention;

[0032] Figure 6 This is a partial structural diagram of part A of the present invention;

[0033] Figure 7 This is a partial structural diagram of part B of the present invention;

[0034] Figure 8The flowchart is for the preparation of this invention.

[0035] In the diagram: 1. Mixing mechanism; 101. Mixing tank; 102. Feed inlet; 103. Feeding pipe; 104. Motor base; 105. Servo motor; 106. Rotating shaft; 107. Fixing plate; 108. Lifting groove; 109. Discharge pipe; 2. Stirring assembly; 201. Baffle; 202. Spiral plate; 203. Through hole; 204. T-shaped spiral groove; 205. Conical push rod; 3. Scraping and turning assembly; 301. Movable block; 302. Scraping arc rod; 303. T-shaped movable rod; 304. Telescopic groove; 305. Compression spring; 306. Turning chamber; 307. Nickel-iron alloy plate; 308. Sliding groove; 309. Connecting buckle; 310. Push spring; 4. Mixing tank; 5. Filtering mechanism; 6. Adjusting tank; 7. Filling mechanism; 8. Electromagnet. Detailed Implementation

[0036] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.

[0037] Please see Figures 1 to 7 An embodiment of the present invention provides an apparatus for preparing acetylmethionine injection, comprising a mixing mechanism 1, a stirring tank 4 on one side of the mixing mechanism 1, a filtering mechanism 5 on one side of the stirring tank 4, an adjusting tank 6 on one side of the filtering mechanism 5, and a filling mechanism 7 on one side of the adjusting tank 6. The mixing mechanism 1, the stirring tank 4, the filtering mechanism 5, the adjusting tank 6 and the filling mechanism 7 are all connected by a conveying mechanism. A rotating shaft 106 is rotatably connected to the middle of the mixing mechanism 1. A stirring assembly 2 and four scraping and turning assemblies 3 are movably installed inside the mixing mechanism 1.

[0038] The stirring assembly 2 includes a baffle 201, a spiral plate 202 and a T-shaped spiral groove 204. The spiral plate 202 is fixedly installed on the outer surface of the rotating shaft 106, and the baffle 201 is fixedly installed on the outer surface of the spiral plate 202. The outer surface of the baffle 201 is provided with a T-shaped spiral groove 204.

[0039] Each scraping and turning assembly 3 includes a movable block 301, a scraping arc rod 302, a T-shaped movable rod 303, and a turning chamber 306. The movable block 301 is movably installed on the inner surface of the mixing mechanism 1. The scraping arc rod 302 is fixedly installed on both sides of the movable block 301. The surface of the scraping arc rod 302 is in contact with the inner wall surface of the mixing mechanism 1. The T-shaped movable rod 303 is movably installed at one end of the movable block 301 facing the center of the mixing mechanism 1. One end of the T-shaped movable rod 303 is engaged with the T-shaped spiral groove 204. The turning chamber 306 is provided inside the bottom end of the movable block 301.

[0040] The scraping and turning assembly 3 also includes a telescopic groove 304, a compression spring 305, a nickel-iron alloy plate 307, a sliding groove 308, a connecting buckle 309, and a push spring 310. The movable block 301 has a telescopic groove 304 at each position where a T-shaped movable rod 303 is installed. One end of each T-shaped movable rod 303 is movably inserted into the telescopic groove 304. A compression spring 305 is movably installed inside each telescopic groove 304. One end of the compression spring 305 is fixedly connected to the telescopic groove 304, and the other end is fixedly connected to the T-shaped movable rod 303. A nickel-iron alloy plate 307 is movably mounted on the bottom surface of the material chamber 306. A sliding groove 308 is provided on the side of the material chamber 306 near the mixing mechanism 1. One end of the nickel-iron alloy plate 307 is slidably mounted inside the sliding groove 308. A push spring 310 is provided between the sliding groove 308 and the nickel-iron alloy plate 307. One end of the push spring 310 is fixedly connected to the sliding groove 308, and the other end is fixedly connected to the nickel-iron alloy plate 307. Connecting buckles 309 are fixedly mounted on the end of the movable block 301 near the inner wall surface of the mixing mechanism 1. Through the cooperation of the nickel-iron alloy plate 307 and the push spring 310, the elastic potential energy of the push spring 310 can push the nickel-iron alloy plate 307, ensuring that the nickel-iron alloy plate 307 keeps the bottom of the material chamber 306 sealed, thus preventing liquid leakage inside the material chamber 306.

[0041] The mixing mechanism 1 includes a mixing tank 101, a feed inlet 102, a feeding pipe 103, a motor base 104, a servo motor 105, a rotating shaft 106, a fixing plate 107, a lifting trough 108, and a discharge pipe 109. The mixing tank 101 is fixedly installed on one side of the mixing tank 4. The feed inlet 102 is fixedly installed on one side of the top of the mixing tank 101, and the feeding pipe 103 is fixedly installed on the other side of the top of the mixing tank 101. The motor base 104 is fixedly installed at the center of the top of the mixing tank 101. A servo motor 105 is fixedly installed at the top of the mixing tank 101. A rotating shaft 106 is movably installed at the center of the mixing tank 101. The output end of the servo motor 105 is connected to the top of the rotating shaft 106 through a coupling. Four fixing plates 107 are fixedly installed on the inner wall surface of the mixing tank 101. Each fixing plate 107 has a lifting groove 108 on its outer surface. A discharge pipe 109 is provided on the rear surface of the mixing tank 101 near the bottom. Electromagnets 8 are fixedly installed inside the lifting groove 108 near the bottom and top.

[0042] The aforementioned stirring assembly 2 also includes through holes 203 and conical push rods 205. The surface of the spiral plate 202 is provided with multiple through holes 203, and a conical push rod 205 is fixedly installed on the top surface of the baffle 201 near the upper opening of the T-shaped spiral groove 204.

[0043] Both the connecting buckle 309 and the lifting groove 108 are T-shaped, and the connecting buckle 309 is movable and snapped into the interior of the lifting groove 108.

[0044] The other end of the T-shaped movable rod 303 is movably inserted into the interior of the T-shaped spiral groove 204, and the surface of the scraper arc rod 302 is in contact with the inner wall surface of the mixing tank 101.

[0045] The bottom surface of the movable block 301 is provided with through holes, which are all connected to the interior of the turning chamber 306.

[0046] Before the device starts operating, the movable block 301 will remain at the bottom of the lifting trough 108 due to gravity. The nickel-iron alloy plate 307 will be attracted by the electromagnet 8 and open the tilting chamber 306, filling the liquid inside the mixing tank 101 into the tilting chamber 306. After the device starts operating, the servo motor 105 is first controlled to drive the rotating shaft 106 to rotate, causing the rotating shaft 106 to drive the spiral plate 202 and the baffle 201 to rotate. At this time, when the baffle 201 rotates, the T-shaped spiral groove 204 on its surface will pass through the positions of the four T-shaped movable rods 303 respectively, so that the four T-shaped movable rods 303 are inserted into the T-shaped spiral groove 204 from the bottom end of the baffle 201 at the bottom position of the lifting trough 108. Then the spiral plate 202 and the baffle 201 continue to rotate. At this time, the T-shaped movable rods 303 will be pushed by the T-shaped spiral groove 204 and drive the movable block 301 to move upward along the lifting trough 108. At this time, the nickel-iron alloy plate 307 will lose the attraction of the electromagnet 8. The material-turning chamber 306 is sealed by the push spring 310, thereby filling the liquid below the mixing tank 101 into the material-turning chamber 306 to prevent leakage. When the movable block 301 rises to the highest position of the lifting groove 108, the T-shaped movable rod 303 will move out of the T-shaped spiral groove 204 from the uppermost end of the baffle 201. The bottom end of the T-shaped movable rod 303 is supported by the baffle 201, so that the movable block 301 stops at the highest position of the lifting groove 108. When the movable block 301 stops at the uppermost position of the lifting groove 108, the nickel-iron alloy plate 307 will be attracted by the electromagnet 8 again and move towards the sliding groove 308, so that the nickel-iron alloy plate 307 no longer seals the material-turning chamber 306. At this time, the liquid inside the material-turning chamber 306 will pour out and mix into the liquid in the upper part of the mixing tank 101, thereby completing the material-turning of the liquid and turning the liquid below to the upper position of the mixing tank 101.

[0047] Subsequently, the spiral plate 202 and the baffle 201 continue to rotate. At this time, the conical push rod 205 will impact the surface of the T-shaped movable rod 303. Through the impact of the inclined surface of the conical push rod 205 on the T-shaped movable rod 303, the T-shaped movable rod 303 is caused to retract into the telescopic groove 304. At this time, the bottom end of the T-shaped movable rod 303 is no longer in contact with the baffle 201, so that the movable block 301 falls along the lifting groove 108 under the action of gravity. At this time, the nickel-iron alloy plate 307 loses the attraction of the electromagnet 8 and is pushed again by the push spring 310 to seal the tipping chamber 306. Until the movable block 301 falls to the lowest position along the lifting groove 108, the T-shaped movable rod 303 will be pushed outward by the compression spring 305, so that the T-shaped movable rod 303 returns to the initial position. Until the spiral plate 202 and the baffle 201 continue to rotate until the T-shaped spiral groove 204 passes the T-shaped movable rod 303, the movable block 301 will stop at the lowest position of the lifting groove. At this time, the nickel-iron alloy plate 307 will be attracted by the electromagnet 8 again and open the tipping chamber 306 to load the liquid located at the bottom of the mixing tank 101 into the tipping chamber 306.

[0048] The outside of the mixing tank 101 is movably mounted on a cooling sleeve, and multiple support columns are fixedly installed at the bottom of the cooling sleeve.

[0049] The outer surface of the baffle 201 is provided with multiple leakage holes near the T-shaped spiral groove 204, and the leakage holes are all connected to the space inside the T-shaped spiral groove 204 near the bottom.

[0050] By adopting the above technical solution, the material entering the T-shaped spiral groove 204 can be leaked out through the leakage hole, preventing it from remaining inside the T-shaped spiral groove 204.

[0051] A method for preparing acetylmethionine injection, the method comprising the following steps:

[0052] S1. Take 10L of benzyl alcohol, 20L of ethanol and 5L of propylene glycol and add them to mixing tank 101 and mix them evenly to obtain a cosolvent.

[0053] S2. Pour the solubilizer and sufficient water for injection into the mixing tank 4, then add 50g of stabilizer and 3kg of acetylmethionine and stir to dissolve.

[0054] S3. The solution obtained by stirring is filtered through the filter mechanism 5 in an environment of 18-26℃, and the filtered solution is poured into the regulating tank 6.

[0055] S4. Adjust the pH of the filtered solution to 9.5-11.0 using ethanolamine, and then sterilize it at high temperature.

[0056] S5. After the prepared acetylmethionine injection solution undergoes a qualification test, it is filled through the filling mechanism 7 and then packaged into a product.

[0057] S6. In step S1, the mixing tank, through the cooperation of baffle 201 and spiral plate 202, allows the acetylmethionine injection solution to be stirred and mixed with the prepared materials. Simultaneously, the materials are transported to the top of the mixing tank 101 via baffle 201, causing materials at the bottom to be moved to the top, preventing uneven mixing. Furthermore, through the cooperation of movable block 301 and T-shaped movable rod 303, the baffle 201 rotates, bringing the T-shaped movable rod 303 into the T-shaped spiral groove 204. This allows the movable block 301 to move up and down outside the fixed plate 107. When the movable block 301 is raised, the material-turning chamber 306 is filled into the mixing tank 101 near the bottom edge. The material is placed in the container. When the T-shaped movable rod 303 moves to the highest position with the T-shaped spiral groove 204, the outer surface of the T-shaped movable rod 303 can be pushed by the conical push rod 205 to retract the T-shaped movable rod 303 into the telescopic groove 304. At this time, the movable block 301 loses support and falls down from the top of the outer side of the fixed plate 107 along the lifting groove 108. At this time, the material located inside the turning chamber 306 will be poured out and returned to the position above the material inside the mixing tank 101, thereby realizing the turning operation. With the setting of the scraping arc rod 302, the movable block 301 can scrape the inner wall surface of the mixing tank 101 through the scraping arc rod 302 during the lifting process to prevent the material from adhering to and remaining on the inner wall surface of the mixing tank 101.

[0058] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from its spirit or essential characteristics. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description. Thus, all variations falling within the meaning and scope of equivalents of the claims are intended to be included within the present invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. An apparatus for preparing acetylmethionine injection, comprising a mixing mechanism (1), a stirring tank (4) on one side of the mixing mechanism (1), a filtering mechanism (5) on one side of the stirring tank (4), an adjusting tank (6) on one side of the filtering mechanism (5), and a filling mechanism (7) on one side of the adjusting tank (6), wherein the mixing mechanism (1), the stirring tank (4), the filtering mechanism (5), the adjusting tank (6), and the filling mechanism (7) are all connected by a conveying mechanism, and a rotating shaft (106) is rotatably connected to the middle of the mixing mechanism (1), characterized in that: The inside of the mixing mechanism (1) is movably installed with a stirring assembly (2) and multiple material scraping and turning assemblies (3); The stirring assembly (2) comprises a baffle (201), a spiral plate (202) and a T-shaped spiral groove (204), the outer surface of the rotating shaft (106) is fixedly installed with the spiral plate (202), the outer surface of the spiral plate (202) is fixedly installed with the baffle (201), and the outer surface of the baffle (201) is provided with the T-shaped spiral groove (204); The material scraping and turning assembly (3) comprises a movable block (301), a material scraping arc rod (302), a T-shaped movable rod (303) and a material turning cavity (306), the movable block (301) is movably installed on the inner surface of the mixing mechanism (1), both side surfaces of the movable block (301) are fixedly installed with the material scraping arc rod (302), the surfaces of the material scraping arc rods (302) are attached to the inner wall surface of the mixing mechanism (1), one end of the movable block (301) towards the center of the mixing mechanism (1) is movably installed with the T-shaped movable rod (303), one end of the T-shaped movable rod (303) is matched with the T-shaped spiral groove (204), and the bottom end of the movable block (301) is internally provided with the material turning cavity (306); The material scraping and turning assembly (3) further comprises a telescopic groove (304), a compression spring (305), a nickel-iron alloy plate (307), a sliding groove (308), a connecting buckle (309) and a pushing spring (310), the position, at which the T-shaped movable rod (303) is installed on the movable block (301), is provided with the telescopic groove (304), one end of the T-shaped movable rod (303) is movably clamped into the inside of the telescopic groove (304), the inside of the telescopic groove (304) is movably installed with the compression spring (305), the compression spring (305) is movably connected with the T-shaped movable rod (303), the bottom end surface in the inside of the material turning cavity (306) is movably installed with the nickel-iron alloy plate (307), one side of the material turning cavity (306) close to the mixing mechanism (1) is provided with the sliding groove (308), one end of the nickel-iron alloy plate (307) is slidably installed in the inside of the sliding groove (308), the sliding groove (308) and the nickel-iron alloy plate (307) are provided with the pushing spring (310), and one end of the movable block (301) close to the inner wall surface of the mixing mechanism (1) is fixedly installed with the connecting buckle (309); The mixing mechanism (1) comprises a mixing tank (101), the inner wall surface of the mixing tank (101) is fixedly installed with four fixed plates (107), the outer surface of each fixed plate (107) is provided with a lifting groove (108), and the rear surface of the mixing tank (101) is provided with a discharge pipe (109) close to the bottom end; The inside of the lifting groove (108) is fixedly installed with an electromagnet (8) close to the bottom end and the top end; The stirring assembly (2) further comprises through holes (203) and a conical push rod (205), the surface of the spiral plate (202) is provided with a plurality of through holes (203), and the top end surface of the baffle (201) is fixedly installed with the conical push rod (205) near the upper end opening of the T-shaped spiral groove (204).

2. The acetylmeth-quinone injection preparation device according to claim 1, characterized in that: The mixing tank (101) is fixedly installed on one side of the stirring tank (4), one side of the top end of the mixing tank (101) is fixedly installed with the feeding port (102), the other side of the top end of the mixing tank (101) is fixedly installed with the feeding pipe (103), the center position of the top end of the mixing tank (101) is fixedly installed with the motor seat (104), the top end of the motor seat (104) is fixedly installed with the servo motor (105), and the center position of the inside of the mixing tank (101) is movably installed with the rotating shaft (106). The output end of the servo motor (105) is connected with the top end of the rotating shaft (106) through a shaft coupling.

3. The acetylmeth-quinone injection preparation device according to claim 2, characterized in that: The connecting buckle (309) and the lifting groove (108) are both T-shaped, and the connecting buckle (309) is movably clamped into the inside of the lifting groove (108).

4. The acetylmeth-quinone injection preparation device according to claim 3, characterized in that: The bottom end surface of the movable block (301) is provided with a through hole, and the through hole is in through connection with the inside of the turnover cavity (306).

5. The acetylmeth-quinone injection preparation device according to claim 4, characterized by: The outside of the mixing tank (101) is movably installed in a cooling sleeve, and a plurality of supporting columns are fixedly installed at the bottom end of the cooling sleeve.

6. The acetylmeth-quinone injection preparation device according to claim 5, characterized by: A plurality of liquid leakage holes are arranged on the outer surface of the baffle (201) near the T-shaped spiral groove (204), and the liquid leakage holes are connected with the space near the lower part of the inside of the T-shaped spiral groove (204).

7. A process for the preparation of an acequinate injection solution as claimed in claim 6, characterized in that: The method comprises the following steps: S1, take 10L of benzyl alcohol, 20L of ethanol and 5L of propylene glycol into the mixing tank (101) and mix uniformly to obtain a cosolvent; S2, pour the cosolvent and enough water for injection into the stirring tank (4), and then add 50g of stabilizer and 3kg of acetylmethylquinoline and stir to dissolve; S3, filter the stirring solution in an environment of 18-26℃ through the filtering mechanism (5), and pour the filtered solution into the adjusting tank (6); S4, adjust the PH value of the filtered solution by using ethanolamine, adjust the PH value to 9.5-11.0, and sterilize in a high-temperature environment; S5, the prepared acetylmethylquinoline injection is first detected for qualification, then filled through the filling mechanism (7), and then packaged into products; S6. In step S1, the mixing tank, through the cooperation of baffle (201) and spiral plate (202), allows the acetylmethionine injection solution to be stirred and mixed with the prepared materials through the baffle (201) and spiral plate (202). At the same time, the materials can be transported to the top position of the mixing tank (101) through the baffle (201), and the materials at the bottom position can be turned to the top position to prevent uneven mixing. Through the cooperation of movable block (301) and T-shaped movable rod (303), the baffle (201) can bring the T-shaped movable rod (303) into the interior of T-shaped spiral groove (204) while rotating, so that the movable block (301) can move up and down outside the fixed plate (107). When the movable block (301) is raised, the interior of the material turning chamber (306) will be filled into the interior of the mixing tank (101) near the bottom edge. When the T-shaped movable rod (303) moves to the highest position with the T-shaped spiral groove (204), the outer surface of the T-shaped movable rod (303) can be pushed by the conical push rod (205) to make the T-shaped movable rod (303) retract into the telescopic groove (304). At this time, the movable block (301) loses support and falls down from the top of the outside of the fixed plate (107) along the lifting groove (108). At this time, the material located inside the turning chamber (306) will be poured out and poured back to the position above the material inside the mixing tank (101), thereby realizing the turning operation. By setting the scraping arc rod (302), the movable block (301) can scrape the inner wall surface of the mixing tank (101) through the scraping arc rod (302) during the lifting process to prevent the material from adhering to and remaining on the inner wall surface of the mixing tank (101).

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